JPS57156433A - Preparation of optical active malic acid or its salt - Google Patents

Preparation of optical active malic acid or its salt

Info

Publication number
JPS57156433A
JPS57156433A JP4021981A JP4021981A JPS57156433A JP S57156433 A JPS57156433 A JP S57156433A JP 4021981 A JP4021981 A JP 4021981A JP 4021981 A JP4021981 A JP 4021981A JP S57156433 A JPS57156433 A JP S57156433A
Authority
JP
Japan
Prior art keywords
malate
crystal
optical active
added
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4021981A
Other languages
Japanese (ja)
Other versions
JPH0134213B2 (en
Inventor
Kaoru Harada
Masayo Matsuyama
Yoshiharu Kataoka
Hiroji Mizumoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FUSO KAGAKU KOGYO
FUSO KAGAKU KOGYO KK
FUSOU KAGAKU KOGYO KK
Original Assignee
FUSO KAGAKU KOGYO
FUSO KAGAKU KOGYO KK
FUSOU KAGAKU KOGYO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FUSO KAGAKU KOGYO, FUSO KAGAKU KOGYO KK, FUSOU KAGAKU KOGYO KK filed Critical FUSO KAGAKU KOGYO
Priority to JP4021981A priority Critical patent/JPS57156433A/en
Publication of JPS57156433A publication Critical patent/JPS57156433A/en
Publication of JPH0134213B2 publication Critical patent/JPH0134213B2/ja
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To obtain the titled high-purity compound without requiring complex operations, by adding a small amount of an optical active l or d-malate crystal to a supersaturated solution of a dl-malate, by crystallizing preferentially the same optical active malate crystal that was added to the solution.
CONSTITUTION: A small amount of optical active l or d-malate crystal is added to a supersaturated solution of a dl-malate, the same optical active malate that was added to the solution is crystallized preferentially, and the separating out crystal is collected. To the mother liquor from which the crystal is collected, a small amount of d or l-malate crystal related to the crystal through optical isomer is added, so that the same optical active malate crystal that was added to the liquor is obtained. The resolution operation can be repeated by adding a proper amount of dl-malate to the mother liquor. The dl-malate is preferably not precipitated as a racemic modification in the supersaturated solution, and an organic acid(salt) except malate is preferably added.
COPYRIGHT: (C)1982,JPO&Japio
JP4021981A 1981-03-19 1981-03-19 Preparation of optical active malic acid or its salt Granted JPS57156433A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4021981A JPS57156433A (en) 1981-03-19 1981-03-19 Preparation of optical active malic acid or its salt

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4021981A JPS57156433A (en) 1981-03-19 1981-03-19 Preparation of optical active malic acid or its salt

Publications (2)

Publication Number Publication Date
JPS57156433A true JPS57156433A (en) 1982-09-27
JPH0134213B2 JPH0134213B2 (en) 1989-07-18

Family

ID=12574651

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4021981A Granted JPS57156433A (en) 1981-03-19 1981-03-19 Preparation of optical active malic acid or its salt

Country Status (1)

Country Link
JP (1) JPS57156433A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4927841A (en) * 1972-07-08 1974-03-12

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4927841A (en) * 1972-07-08 1974-03-12

Also Published As

Publication number Publication date
JPH0134213B2 (en) 1989-07-18

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