JPS57156433A - Preparation of optical active malic acid or its salt - Google Patents
Preparation of optical active malic acid or its saltInfo
- Publication number
- JPS57156433A JPS57156433A JP4021981A JP4021981A JPS57156433A JP S57156433 A JPS57156433 A JP S57156433A JP 4021981 A JP4021981 A JP 4021981A JP 4021981 A JP4021981 A JP 4021981A JP S57156433 A JPS57156433 A JP S57156433A
- Authority
- JP
- Japan
- Prior art keywords
- malate
- crystal
- optical active
- added
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the titled high-purity compound without requiring complex operations, by adding a small amount of an optical active l or d-malate crystal to a supersaturated solution of a dl-malate, by crystallizing preferentially the same optical active malate crystal that was added to the solution.
CONSTITUTION: A small amount of optical active l or d-malate crystal is added to a supersaturated solution of a dl-malate, the same optical active malate that was added to the solution is crystallized preferentially, and the separating out crystal is collected. To the mother liquor from which the crystal is collected, a small amount of d or l-malate crystal related to the crystal through optical isomer is added, so that the same optical active malate crystal that was added to the liquor is obtained. The resolution operation can be repeated by adding a proper amount of dl-malate to the mother liquor. The dl-malate is preferably not precipitated as a racemic modification in the supersaturated solution, and an organic acid(salt) except malate is preferably added.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4021981A JPS57156433A (en) | 1981-03-19 | 1981-03-19 | Preparation of optical active malic acid or its salt |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4021981A JPS57156433A (en) | 1981-03-19 | 1981-03-19 | Preparation of optical active malic acid or its salt |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57156433A true JPS57156433A (en) | 1982-09-27 |
JPH0134213B2 JPH0134213B2 (en) | 1989-07-18 |
Family
ID=12574651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4021981A Granted JPS57156433A (en) | 1981-03-19 | 1981-03-19 | Preparation of optical active malic acid or its salt |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57156433A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4927841A (en) * | 1972-07-08 | 1974-03-12 |
-
1981
- 1981-03-19 JP JP4021981A patent/JPS57156433A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4927841A (en) * | 1972-07-08 | 1974-03-12 |
Also Published As
Publication number | Publication date |
---|---|
JPH0134213B2 (en) | 1989-07-18 |
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