JPS57140780A - Preparation of dibenzoxepine derivative - Google Patents
Preparation of dibenzoxepine derivativeInfo
- Publication number
- JPS57140780A JPS57140780A JP1121082A JP1121082A JPS57140780A JP S57140780 A JPS57140780 A JP S57140780A JP 1121082 A JP1121082 A JP 1121082A JP 1121082 A JP1121082 A JP 1121082A JP S57140780 A JPS57140780 A JP S57140780A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- agent
- formula
- derivative
- oxepin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The 6,11-dihydrodibenz[b,e]oxepin-11-one derivative of formulaI(R is H, halogen or lower alkoxy; R1 is H or lower alkyl).
EXAMPLE: 6,11-Dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid methyl ester.
USE: Antiphlogistic agent, analgesic and antipyretic agent, and blood platelet coagulation inhibiting agent.
PROCESS: The compound of formulaIis prepared by treating the compound of formula II with thallium trinitrate in an alcoholic solvent in the presence of an acid catalyst (e.g. perchloric acid, nitric acid, etc.), and if necessary, hydrolyzing the product. The reaction is carried out at 0W60°C for 1W20 hours. The compound of formula II is also a novel substance, and can be obtained by oxidizing the compound of formula III with an oxidizing agent (e.g. chromic anhydride).
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1121082A JPS57140780A (en) | 1982-01-27 | 1982-01-27 | Preparation of dibenzoxepine derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1121082A JPS57140780A (en) | 1982-01-27 | 1982-01-27 | Preparation of dibenzoxepine derivative |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10812974A Division JPS602308B2 (en) | 1974-09-19 | 1974-09-19 | Method for producing dibenzoxepine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS57140780A true JPS57140780A (en) | 1982-08-31 |
Family
ID=11771633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1121082A Pending JPS57140780A (en) | 1982-01-27 | 1982-01-27 | Preparation of dibenzoxepine derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57140780A (en) |
-
1982
- 1982-01-27 JP JP1121082A patent/JPS57140780A/en active Pending
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