JPS57120580A - Dibenzoxazepinone derivative - Google Patents
Dibenzoxazepinone derivativeInfo
- Publication number
- JPS57120580A JPS57120580A JP598681A JP598681A JPS57120580A JP S57120580 A JPS57120580 A JP S57120580A JP 598681 A JP598681 A JP 598681A JP 598681 A JP598681 A JP 598681A JP S57120580 A JPS57120580 A JP S57120580A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- lower alkyl
- formulai
- dibenzoxazepinone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
NEW MATERIAL:A dibenzoxazepinone derivative of formulaI(R1 is at least one substitutent selected from H, haglogen, lower alkyoxy and straight-chained lower alkyl group of at least one carbon atom; R2 is H, lower alkyl; R3, R4 are lower alkyl or incorporate together with a nitrogen atom to form a heterocyclic ring; A is lower alkylene) or its salt.
EXAMPLE: 10-{2-( Dimethylamino )ethyl}-8-ethoxycarbonyl-dibenzo[b,f][1,4] oxazipin-11(10H)-one.
USE: It is used as a medicine, because of its high antiulcerative action and low toxicity.
PREPARATION: The reaction of a compound of formula II with another compound of formula III (X is halogen) in an inert solvent such as dimethylformamide gives the compound of formulaI. The compound of formula II is novel, which is synthesized by reaction of an alkali salt of a compound of formula IV with a substituted nitrobenzene, followed by catalytic reduction and ring closure with heat of the product.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP598681A JPS57120580A (en) | 1981-01-20 | 1981-01-20 | Dibenzoxazepinone derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP598681A JPS57120580A (en) | 1981-01-20 | 1981-01-20 | Dibenzoxazepinone derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57120580A true JPS57120580A (en) | 1982-07-27 |
JPH0157112B2 JPH0157112B2 (en) | 1989-12-04 |
Family
ID=11626119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP598681A Granted JPS57120580A (en) | 1981-01-20 | 1981-01-20 | Dibenzoxazepinone derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57120580A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11649218B2 (en) * | 2018-03-09 | 2023-05-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | C-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same |
-
1981
- 1981-01-20 JP JP598681A patent/JPS57120580A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11649218B2 (en) * | 2018-03-09 | 2023-05-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | C-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same |
Also Published As
Publication number | Publication date |
---|---|
JPH0157112B2 (en) | 1989-12-04 |
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