JPS5549376A - Cephalosporin analog - Google Patents
Cephalosporin analogInfo
- Publication number
- JPS5549376A JPS5549376A JP12240378A JP12240378A JPS5549376A JP S5549376 A JPS5549376 A JP S5549376A JP 12240378 A JP12240378 A JP 12240378A JP 12240378 A JP12240378 A JP 12240378A JP S5549376 A JPS5549376 A JP S5549376A
- Authority
- JP
- Japan
- Prior art keywords
- azide
- formula
- alkyl
- cephalosporins
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
NEW MATERIAL:Cephalosporin analogs of formula I (X is amino, azide, phthalyl imino; R1 is H, halogen, hydroxyl, lower alkoxy, aryloxy; R2 is the same as R1 or lower alkyl, azide, nitrile; R3 is H, alkyl, aryl) and their salts.
EXAMPLE: (±) cis, 2-t-Butyloxyacrbonyl-7-azide-1-azabicyclo[4, 2, 0]octo-2-ene- 8-one.
USE: Synthetic intermediatedes of cephalosporins; the introduction of various kinds of acyl groups into the amino group of the compound of formula I in which X is primary amino gives cephalosporins having antibacterial activity.
PREPARATION: According to reaction equations, from compounds of formula II and III are obtained compounds of formula Ia where X is azide, phthalylimino, R1 is H, R2 is H, lower alkyl, R3 is alkyl, aryl, aralkyl.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12240378A JPS5549376A (en) | 1978-10-04 | 1978-10-04 | Cephalosporin analog |
NO790955A NO790955L (en) | 1978-03-25 | 1979-03-21 | CEPHALOSPORINE ANALOGUE CARBACEFEM COMPOUNDS AND PROCEDURES FOR MANUFACTURE THEREOF |
SE7902598A SE7902598L (en) | 1978-03-25 | 1979-03-22 | CEPHALOSPORINE ANALOGES |
AU45367/79A AU528675B2 (en) | 1978-03-25 | 1979-03-23 | Cephalosporin analogs |
CA324,178A CA1133903A (en) | 1978-03-25 | 1979-03-23 | Cephalosporin analogs |
DK119979A DK119979A (en) | 1978-03-25 | 1979-03-23 | CEPHALOSPORINE ANALOG AND METHOD OF MANUFACTURE |
FR7907414A FR2420537B1 (en) | 1978-03-25 | 1979-03-23 | PRODUCTS SIMILAR TO CEPHALOSPORIN AND THEIR PREPARATION PROCESS |
ES478919A ES478919A1 (en) | 1978-03-25 | 1979-03-23 | A procedure for the production of cefalosporine analogs. (Machine-translation by Google Translate, not legally binding) |
US06/023,645 US4291164A (en) | 1978-03-20 | 1979-03-23 | Cephalosporin analogs and methods for production thereof |
NL7902316A NL7902316A (en) | 1978-03-25 | 1979-03-23 | CEPHALOSPORIN DERIVATIVES. |
AR275946A AR226681A1 (en) | 1978-03-25 | 1979-03-26 | PROCEDURE FOR PRODUCING ANALOGS OF CEPHALOSPORIN |
CH278979A CH642369A5 (en) | 1978-03-25 | 1979-03-26 | CEPHALOSPORIN ANALOGS. |
IT21290/79A IT1115153B (en) | 1978-03-25 | 1979-03-26 | Cephalosporin analogues and procedure for their preparation |
DE2911786A DE2911786C2 (en) | 1978-03-25 | 1979-03-26 | Carbacephem derivatives and their uses |
GB7910506A GB2017102B (en) | 1978-03-25 | 1979-03-26 | Cephalosporin analogues |
ES486993A ES486993A1 (en) | 1978-03-25 | 1979-12-17 | A procedure for the production of cefalosporine analogs. (Machine-translation by Google Translate, not legally binding) |
ES486995A ES486995A1 (en) | 1978-03-25 | 1979-12-17 | A procedure for the preparation of a b-lactama (Machine-translation by Google Translate, not legally binding) |
ES486996A ES486996A1 (en) | 1978-03-25 | 1979-12-17 | A procedure for the production of cefalosporine analogs. (Machine-translation by Google Translate, not legally binding) |
ES486997A ES486997A1 (en) | 1978-03-25 | 1979-12-17 | A procedure for the production of cefalosporine analogs. (Machine-translation by Google Translate, not legally binding) |
ES486994A ES486994A1 (en) | 1978-03-25 | 1979-12-17 | A procedure for the production of cefalosporine analogs. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12240378A JPS5549376A (en) | 1978-10-04 | 1978-10-04 | Cephalosporin analog |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5549376A true JPS5549376A (en) | 1980-04-09 |
Family
ID=14834922
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12240378A Pending JPS5549376A (en) | 1978-03-20 | 1978-10-04 | Cephalosporin analog |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5549376A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5630976A (en) * | 1979-08-24 | 1981-03-28 | Kyowa Hakko Kogyo Co Ltd | Optically active cephalosporin analog |
-
1978
- 1978-10-04 JP JP12240378A patent/JPS5549376A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5630976A (en) * | 1979-08-24 | 1981-03-28 | Kyowa Hakko Kogyo Co Ltd | Optically active cephalosporin analog |
JPS6350356B2 (en) * | 1979-08-24 | 1988-10-07 | Kyowa Hakko Kogyo Kk |
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