JPS55139396A - Monacolin j, new type of physiologically actice substance, and its preparation - Google Patents
Monacolin j, new type of physiologically actice substance, and its preparationInfo
- Publication number
- JPS55139396A JPS55139396A JP4424979A JP4424979A JPS55139396A JP S55139396 A JPS55139396 A JP S55139396A JP 4424979 A JP4424979 A JP 4424979A JP 4424979 A JP4424979 A JP 4424979A JP S55139396 A JPS55139396 A JP S55139396A
- Authority
- JP
- Japan
- Prior art keywords
- monacolin
- preparation
- physiologically
- substance
- actice
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000126 substance Substances 0.000 title abstract 2
- 229930185723 monacolin Natural products 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 238000004458 analytical method Methods 0.000 abstract 2
- ZDFOBOYQVYMVCW-IRUSZSJRSA-N monacolin J Chemical compound C([C@@H]1[C@H]2[C@@H](O)C[C@H](C=C2C=C[C@@H]1C)C)C[C@@H]1C[C@@H](O)CC(=O)O1 ZDFOBOYQVYMVCW-IRUSZSJRSA-N 0.000 abstract 2
- ZDFOBOYQVYMVCW-UHFFFAOYSA-N monocolin J Natural products CC1C=CC2=CC(C)CC(O)C2C1CCC1CC(O)CC(=O)O1 ZDFOBOYQVYMVCW-UHFFFAOYSA-N 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000031003 Monascus ruber Species 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 239000003208 petroleum Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000004809 thin layer chromatography Methods 0.000 abstract 1
Landscapes
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Compounds Of Unknown Constitution (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4424979A JPS55139396A (en) | 1979-04-13 | 1979-04-13 | Monacolin j, new type of physiologically actice substance, and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4424979A JPS55139396A (en) | 1979-04-13 | 1979-04-13 | Monacolin j, new type of physiologically actice substance, and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55139396A true JPS55139396A (en) | 1980-10-31 |
| JPS6113798B2 JPS6113798B2 (enrdf_load_stackoverflow) | 1986-04-15 |
Family
ID=12686252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4424979A Granted JPS55139396A (en) | 1979-04-13 | 1979-04-13 | Monacolin j, new type of physiologically actice substance, and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55139396A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0314435A2 (en) | 1987-10-27 | 1989-05-03 | Sankyo Company Limited | Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition, processes for their preparation and compositions containing them |
| WO2010043748A1 (es) | 2008-10-15 | 2010-04-22 | Neuron Biopharma, S.A. | Biosíntesis de derivados de monacolina j |
-
1979
- 1979-04-13 JP JP4424979A patent/JPS55139396A/ja active Granted
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0314435A2 (en) | 1987-10-27 | 1989-05-03 | Sankyo Company Limited | Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition, processes for their preparation and compositions containing them |
| WO2010043748A1 (es) | 2008-10-15 | 2010-04-22 | Neuron Biopharma, S.A. | Biosíntesis de derivados de monacolina j |
| ES2343049A1 (es) * | 2008-10-15 | 2010-07-21 | Neuron Biopharma, S.A. | Biosintesis de derivados de monacolina j. |
| ES2343049B1 (es) * | 2008-10-15 | 2011-06-10 | Neuron Biopharma, S.A. | Biosintesis de derivados de monacolina j. |
| EP2380571A4 (en) * | 2008-10-15 | 2012-07-11 | Neuron Biopharma Sa | BIOSYNTHESIS OF MONACOLINE J DERIVATIVES |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6113798B2 (enrdf_load_stackoverflow) | 1986-04-15 |
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