JPS5489086A - Preparation of coenzyme q10 - Google Patents

Preparation of coenzyme q10

Info

Publication number
JPS5489086A
JPS5489086A JP15820277A JP15820277A JPS5489086A JP S5489086 A JPS5489086 A JP S5489086A JP 15820277 A JP15820277 A JP 15820277A JP 15820277 A JP15820277 A JP 15820277A JP S5489086 A JPS5489086 A JP S5489086A
Authority
JP
Japan
Prior art keywords
coenzyme
acid
precursor
substance
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15820277A
Other languages
Japanese (ja)
Other versions
JPS5937949B2 (en
Inventor
Akira Furuya
Kazumi Araki
Hajime Koda
Masahiro Sugimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP52158202A priority Critical patent/JPS5937949B2/en
Publication of JPS5489086A publication Critical patent/JPS5489086A/en
Publication of JPS5937949B2 publication Critical patent/JPS5937949B2/en
Expired legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To increase the production of coenzyme Q10 in the fermentative production of coenzyme Q10, by adding a precursor of coenzyme Q10 to the cultivation medium.
CONSTITUTION: Coenzyme Q10-producing bacteria, e.g. Paracoccus denitrificans ATCC 19367, are cultured in a medium containing a precursor for the biosynthesis of coenzyme Q10, its metabolism-relating substance, or a natural substance containing the same, and the coenzyme Q10 is separated from the bacterial cells. The precursor or the metablism-relating substance is, e.g. L-tyrosine, L-phenylalanine, procatechuic acid, p-coumaric acid, p-hydroxybenzoic acid, trans-cinnamic acid, shikimic acid, methionine, mevalonic acid, isoprenyl alcohol, vaniline, etc., and the natural substance is, e.g. castings of silk worm, extract of tobacco leaves, etc. The amount of the additive in the medium is 0.1-2W/V%, pref. 0.5-1W/V%.
COPYRIGHT: (C)1979,JPO&Japio
JP52158202A 1977-12-27 1977-12-27 Production method of coenzyme Q↓1↓0 Expired JPS5937949B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP52158202A JPS5937949B2 (en) 1977-12-27 1977-12-27 Production method of coenzyme Q↓1↓0

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52158202A JPS5937949B2 (en) 1977-12-27 1977-12-27 Production method of coenzyme Q↓1↓0

Publications (2)

Publication Number Publication Date
JPS5489086A true JPS5489086A (en) 1979-07-14
JPS5937949B2 JPS5937949B2 (en) 1984-09-12

Family

ID=15666500

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52158202A Expired JPS5937949B2 (en) 1977-12-27 1977-12-27 Production method of coenzyme Q↓1↓0

Country Status (1)

Country Link
JP (1) JPS5937949B2 (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55111793A (en) * 1979-02-21 1980-08-28 Mitsubishi Gas Chem Co Inc Production of coenzyme q10
JPS5739789A (en) * 1980-08-22 1982-03-05 Nisshin Flour Milling Co Ltd Preparation of coenzyme q10
JPS57102192A (en) * 1980-12-17 1982-06-25 Dainippon Ink & Chem Inc Preparation of coenzyme q10
JPS58146285A (en) * 1982-02-22 1983-08-31 Kyowa Hakko Kogyo Co Ltd Preparation of coenyzme q10
JPS63102691A (en) * 1987-09-11 1988-05-07 Nisshin Flour Milling Co Ltd Production of coenzyme q12
CN100389201C (en) * 2006-02-09 2008-05-21 东北林业大学 Method of processing coenzyme Q10 raw materials
KR100907296B1 (en) * 2007-10-17 2009-07-13 한국생산기술연구원 Rodotorula sp. JSU150-13 with high productivity of coenzyme Q10, and the producing method of Coenzyme Q10 using the strain

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55111793A (en) * 1979-02-21 1980-08-28 Mitsubishi Gas Chem Co Inc Production of coenzyme q10
JPS5714155B2 (en) * 1979-02-21 1982-03-23
JPS5739789A (en) * 1980-08-22 1982-03-05 Nisshin Flour Milling Co Ltd Preparation of coenzyme q10
JPS6310997B2 (en) * 1980-08-22 1988-03-10 Nisshin Flour Milling Co
JPS57102192A (en) * 1980-12-17 1982-06-25 Dainippon Ink & Chem Inc Preparation of coenzyme q10
JPH0255037B2 (en) * 1980-12-17 1990-11-26 Dainippon Inki Kagaku Kogyo Kk
JPS58146285A (en) * 1982-02-22 1983-08-31 Kyowa Hakko Kogyo Co Ltd Preparation of coenyzme q10
JPH0369517B2 (en) * 1982-02-22 1991-11-01 Kyowa Hakko Kogyo Kk
JPS63102691A (en) * 1987-09-11 1988-05-07 Nisshin Flour Milling Co Ltd Production of coenzyme q12
JPH0371119B2 (en) * 1987-09-11 1991-11-12 Nisshin Flour Milling Co
CN100389201C (en) * 2006-02-09 2008-05-21 东北林业大学 Method of processing coenzyme Q10 raw materials
KR100907296B1 (en) * 2007-10-17 2009-07-13 한국생산기술연구원 Rodotorula sp. JSU150-13 with high productivity of coenzyme Q10, and the producing method of Coenzyme Q10 using the strain

Also Published As

Publication number Publication date
JPS5937949B2 (en) 1984-09-12

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