JPS5159884A - - Google Patents

Info

Publication number
JPS5159884A
JPS5159884A JP49133281A JP13328174A JPS5159884A JP S5159884 A JPS5159884 A JP S5159884A JP 49133281 A JP49133281 A JP 49133281A JP 13328174 A JP13328174 A JP 13328174A JP S5159884 A JPS5159884 A JP S5159884A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP49133281A
Other languages
Japanese (ja)
Other versions
JPS6028826B2 (en
Inventor
Toshihiro Ishiguro
Yasushi Mino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP49133281A priority Critical patent/JPS6028826B2/en
Priority to DE19752551355 priority patent/DE2551355A1/en
Priority to GB4724075A priority patent/GB1477088A/en
Priority to NL7513425A priority patent/NL7513425A/en
Priority to BE161968A priority patent/BE835689A/en
Priority to ES442762A priority patent/ES442762A1/en
Priority to FR7535204A priority patent/FR2291757A1/en
Priority to CA239,892A priority patent/CA1074311A/en
Publication of JPS5159884A publication Critical patent/JPS5159884A/ja
Priority to US05/793,356 priority patent/US4091220A/en
Priority to US05/882,891 priority patent/US4153794A/en
Publication of JPS6028826B2 publication Critical patent/JPS6028826B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
JP49133281A 1974-11-19 1974-11-19 Method for producing benzylamine derivatives Expired JPS6028826B2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP49133281A JPS6028826B2 (en) 1974-11-19 1974-11-19 Method for producing benzylamine derivatives
DE19752551355 DE2551355A1 (en) 1974-11-19 1975-11-15 N-BENZYLPIPERAZINE
GB4724075A GB1477088A (en) 1974-11-19 1975-11-17 N-benzylpiperazines
NL7513425A NL7513425A (en) 1974-11-19 1975-11-17 PROCESS FOR THE PREPARATION OF NEW BENZYLAMINE DERIVATIVES.
ES442762A ES442762A1 (en) 1974-11-19 1975-11-18 N-benzylpiperazines
BE161968A BE835689A (en) 1974-11-19 1975-11-18 N-BENZYLPIPERAZINES
FR7535204A FR2291757A1 (en) 1974-11-19 1975-11-18 N-BENZYLPIPERAZINES
CA239,892A CA1074311A (en) 1974-11-19 1975-11-18 N-benzlpiperazines
US05/793,356 US4091220A (en) 1974-11-19 1977-05-03 Morpholinocarbonyl alkyl N-benzylpiperazines
US05/882,891 US4153794A (en) 1974-11-19 1978-03-01 N-Benzylpiperazines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49133281A JPS6028826B2 (en) 1974-11-19 1974-11-19 Method for producing benzylamine derivatives

Publications (2)

Publication Number Publication Date
JPS5159884A true JPS5159884A (en) 1976-05-25
JPS6028826B2 JPS6028826B2 (en) 1985-07-06

Family

ID=15100960

Family Applications (1)

Application Number Title Priority Date Filing Date
JP49133281A Expired JPS6028826B2 (en) 1974-11-19 1974-11-19 Method for producing benzylamine derivatives

Country Status (8)

Country Link
JP (1) JPS6028826B2 (en)
BE (1) BE835689A (en)
CA (1) CA1074311A (en)
DE (1) DE2551355A1 (en)
ES (1) ES442762A1 (en)
FR (1) FR2291757A1 (en)
GB (1) GB1477088A (en)
NL (1) NL7513425A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4618677A (en) * 1984-05-31 1986-10-21 Boehringer Ingelheim Limited Substituted phenylalkyl-(piperazinyl or homopiperazinyl)alkyl-thiols and -thiocarbamates useful for the treatment of immunological, inflammatory, and allergic disorders
US4722926A (en) * 1984-11-05 1988-02-02 Boehringer Ingelheim Limited Substituted phenylalkyl-(piperazinyl or homopiperazinyl)alkyl thiols and thiocarbamates useful for the treatment of immunological, inflammatory, and allergic disorders
US6124299A (en) * 1997-02-24 2000-09-26 Zymogenetics, Inc. Calcitonin mimetics
US6268367B1 (en) 1998-02-23 2001-07-31 Zymogenetics, Inc. Piperazine derivatives for treating bone deficit conditions

Also Published As

Publication number Publication date
DE2551355A1 (en) 1976-05-20
FR2291757B1 (en) 1979-09-21
NL7513425A (en) 1976-05-21
GB1477088A (en) 1977-06-22
FR2291757A1 (en) 1976-06-18
JPS6028826B2 (en) 1985-07-06
CA1074311A (en) 1980-03-25
ES442762A1 (en) 1977-04-16
BE835689A (en) 1976-05-18

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