JPH10229995A - Device for suppressing inflammation - Google Patents

Abstract

PROBLEM TO BE SOLVED: To effectively suppress inflammation (itching) by installing a heating means attaining to a specific range of temperature and warming the affected part by bringing the heating means into contact with the inflammatory part. SOLUTION: In controlling itching due to an insect bite, atopic dermatitis, etc., a pen type inflammation suppressing device is employed using a heating wire. This inflammation suppressing device is so constituted as to contain a power source 1, temperature controller 2 for freely adjusting temperature, radiating panel 3 which uses an aluminum plate and which is silver plated on the surface, and a heating element 5 utilizing a chemical reaction such as a disposable body warmer. In addition, for the purpose of long-term use, an adhesive tape is fitted on the surface of the heating element 5, making it possible to stick the element to the skin; also, in avoiding a low temperature burn incident to a long-term use, the device is constituted such that a spacer is interposed between the heating element and the skin. The heating element may be a steam generating device instead, which may control skin dryness by jetting steam.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an inflammation suppressing device used to reduce inflammation (itch) associated with insect bites and atopic dermatitis.

[0002]

2. Description of the Related Art In recent years, environmental degradation due to air pollution and the like has been remarkable, and cases of causing new diseases to the human body are increasing.

[0003] In addition, when a mosquito bites outdoors in the summer, it is very likely that everyone experiences itching.

[0004] When such itching occurs, inflammation (itch) has been conventionally suppressed by directly applying to the affected area of the inflammation (itch) using various agents such as ammonia, L-menthol and antihistamines and steroids. Was.

[0005]

However, the above-mentioned conventional anti-inflammatory (itch) inhibitors have not been suitable for use on allergic skin. It was also unsuitable for those who felt uncomfortable with the stickiness and fragrance of the affected area.

The present invention has been made in view of the above-mentioned problems of the prior art, and has as its object to provide a new type of inflammation (itch) suppressing apparatus which can be applied not only to insect bites but also to medical use and has little skin irritation. I do. And it aims at being applicable also to the person who is uncomfortable with the stickiness and aroma of skin.

[0007]

The inflammation suppressing device of the present invention is characterized by suppressing inflammation (itch) by heat.

[0008] Further, heat generation methods include chemical reaction, catalytic combustion,
It is a heating wire, characterized in that the temperature control can be freely adjusted within a range of 40-50 ° C. and that it can be moisturized by steam.

According to the present invention, novel inflammation (itch) can be suppressed by the above constitution. Furthermore, it can be used for allergic dermatitis by freely selecting a drug. Further, the inflammation (itch) suppressing device of the present invention can be used for patients with atopic dermatitis, and can reduce skin dryness associated with atopic dermatitis due to the moisturizing effect of water vapor.

Further, in the present invention, inflammation (itch) can be suppressed without using any drug, and inflammation (itch) can be reduced without an unpleasant fragrance.

[0011]

Embodiments of the present invention will be described below.

(Embodiment 1) First, the present method will be described. It has been empirically discovered that this heat-induced inflammation (itch) suppression effect is significantly reduced by treating the insect bite at 45-50 ° C. Therefore, the effect of suppressing the itching by the heat treatment was actually examined. In the experiment, the hair on the back of the rabbit was shaved with a razor, and the exposed skin of the rabbit was bitten by the mosquito by forcibly putting it in an environment where 100 mosquitoes / m ^{3 were} present, thereby producing an inflamed model affected area. The inflamed portion of the model was heated to 45 ° C. with an electric heating device, and the area was measured from the vertical and horizontal diameters of the inflamed site every 10 seconds, and the regression was used to determine the effect. FIG. 1 shows the result. Thirty seconds after the heating, the area of the inflamed site was reduced to about half.

(Example 2) It has been empirically discovered that the effect of suppressing inflammation (itch) due to heat can be remarkably reduced by treating an insect bite at 45-50 ° C. Then, the mechanism was actually investigated about the effect. The amount of histamine generated in the affected part of the insect bite was examined using liquid chromatography, and how it changed with or without heat treatment was examined. As shown in FIG. 2, it was found that the amount of histamine was reduced depending on the heat treatment time. This method
After shaving the rat's hair and exposing the skin, mosquito bites the exposed part and the affected part expands and itching starts.
It was investigated how the amount of histamine changes by the heat treatment. Whether the rat began to feel itching was determined by whether the rat began to bite the affected area with the mouth.

(Example 3) An examination was made as to how this itching suppressing effect changes with temperature.
The effect of the treatment at each temperature was determined by the amount of histamine after heating for 30 seconds.

As a result, the treatment at 50 ° C. was most effective as shown in FIG. However, from 45 ° C, it is almost effectively equivalent, and 4 ° C to avoid low temperature burns.
5 ° C. is considered appropriate.

Example 4 A chemical reaction utilizing the reaction heat of the reaction between paulownia ash and oxygen in the air used as a heat source in an ordinary disposable hand warmer, an electrical reaction using a heating wire, and a combustion catalytic reaction. It was used. The temperature of each heat source can be freely adjusted within a range of 40 ° C. to 50 ° C. The temperature was set to 45 ° C., and the effects of each heat source were compared. As shown in FIG. 4, the one using a heating wire was the most effective. This is because the method using the heating wire is easy to control the temperature and the heat supply is constant.

(Example 5) A heat generating apparatus having the structure shown in FIGS. 5-7 was prepared. FIG. 5 uses a heating wire and is characterized by a pen shape. Further, a temperature controller 2 is provided inside, so that the temperature can be freely adjusted according to the degree of symptoms. The radiator plate 3 is made of an aluminum plate and silver-plated on the surface. Next, FIG. 6 shows a heat generating device 5 using a chemical reaction, which has the same configuration as a so-called disposable hand warmer.
It can be attached to the skin. However, in order to avoid long-term use, the heat generating portion is prevented from directly touching the skin by using a spacer 7 between the heat generating portion and the skin to avoid a low-temperature burn. Finally, the heat generating device 5 of FIG. This has the effect of suppressing skin dryness to reduce itching other than insect bites, for example, due to atopic dermatitis.

When the invented device was pressed against the affected part of a mosquito by the inventor himself, an experiment was conducted. As a result, itching was suppressed very quickly, the swelling was regressed, and the itching was not reproduced.

[0019]

The inflammation (itch) suppressing device of the present invention can be used as an anti-itch. Since the present invention does not use any skin irritating agent, irritation to the skin and the like can be reduced. Further, by using a heat source utilizing a chemical reaction, the effect can be maintained and irritation to the skin can be reduced. In addition, the inflammation (itch) suppressing device of the present invention can contribute to alleviation of symptoms of atopic dermatitis by combination with a moisturizing water vapor.

[Brief description of the drawings]

FIG. 1 is a diagram showing the effect of suppressing inflammation (itch) by heat.

FIG. 2 is a graph showing that the effect of suppressing inflammation (itch) due to heat was examined based on the amount of histamine.

FIG. 3 is a diagram showing the effect of suppressing inflammation (itch) due to heat (temperature dependence).

FIG. 4 is a graph showing the effect of suppressing inflammation (itching) by heating element.

FIG. 5 is a configuration diagram of a pen-type itching control device using a heating wire exhibiting the effects of the present invention.

FIG. 6 is a configuration diagram of a seal-type itching suppressing device utilizing heat generated by a chemical reaction that exhibits the effects of the present invention.

FIG. 7 is a configuration diagram of an itch suppressing device provided with a steam generating device exhibiting the effects of the present invention.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Power supply 2 Temperature controller 3 Heat sink 4 Outer frame 5 Heating element 6 Adhesive tape 7 Spacer 8 Moisturizing tank 9 Steam generator 10 Steam generating nozzle

Continued on the front page (72) Inventor Makoto Takeya 1006 Kazuma Kadoma, Kadoma City, Osaka Matsushita Electric Industrial Co., Ltd.

Claims (6)

[Claims] 1. A heat generating means for generating a temperature of 45-50 ° C., wherein said heat generating means is brought into contact with a site where inflammation has occurred, whereby the affected area is heated by heat and the inflammation is suppressed. Inflammation suppression device. 2. The inflammation suppression apparatus according to claim 1, wherein at least one of a chemical reaction, a heating wire, catalytic combustion, and combustion with a liquid or gaseous fuel is used as the heat generating means. 3. The inflammation suppressing apparatus according to claim 1, wherein the heat generation temperature of the heat generating means can be freely adjusted within a range of 40 to 55 ° C. 4. The inflammation suppressing device according to claim 1, wherein the heat generating means is provided with a steam generating device at 40-55 ° C. 5. The apparatus according to claim 4, wherein various anti-inflammatory agents and humectants are mixed in the water vapor. 6. The inflammation suppressing device according to claim 1, wherein the inflammation suppressing device is a pen type, a band type, and a seal, and can be used for a large part including the affected part directly and the affected part.