JPH09225037A - Dispenser for guide wire - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a dispenser for a guide wire, which enables smoothly moving in or out of the guide wire with a small resistance in the insertion or withdrawal of the guide wire and, moreover, facilitates the injection of water for wetting the guide wire. SOLUTION: There are arranged a dispenser body 1 comprising a tube and a guide wire supply part 2 comprising a tube and a connector part 3. The connector part 3 has a curved lumen part 6 and a linear lumen part 7 branched off at an intermediate point of the curved lumen part 6 while extending along a tangent line of the long axis of the curved lumen part 6. Both ends of the dispenser body 1 are linked respectively to both ends of the curved lumen part 6 of the connector part 3 to make the lumens of the dispenser body communicate with one another while the rear end of the guide wire supply part 2 is linked to the tip of the linear lumen part 7 of the connector part 3.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a dispenser for a guide wire. More specifically, according to the present invention, a guide wire coated with a hydrophilic coating can be stored in a state of being immersed in water, a long guide wire can be stored, and the guide wire can be smoothly taken in and out with little resistance. The present invention relates to a dispenser for a guide wire that can be used.

[0002]

2. Description of the Related Art In recent years, with the progress of medical technology, interventional radiology for performing treatment and diagnosis via a catheter under a real-time display image has been widely used. In interventional radiology, a guide wire is first inserted into the body cavity through a puncture needle, and then the catheter is pushed over the guide wire and pushed to the target affected area, in order to improve the slipperiness of the guide wire in the body cavity. In addition, it is common practice to apply a hydrophilic coating to the guide wire. As the hydrophilic coating material, for example, polyvinyl alcohol, polyvinylpyrrolidone, maleic acid-based polymer, polyacrylamide and the like, which are generally considered to be hydrophilic polymers, are often used. In order for the guide wire coated with these hydrophilic coatings to exhibit the original slipperiness, it is naturally necessary to immerse the surface sufficiently in water to form a sufficient water film on the surface of the guide wire. In the early days of guide wire dispensers, a straightener equipped with a guide wire supply port was provided at the tip of a main body tube having a length sufficient to accommodate a long guide wire, and a liquid supply port was provided at the end. . Although such a guide wire dispenser is usually made of a slippery material such as polyethylene, the main body tube is long and difficult to handle, the material is poorly wet with water, and water easily collects even when water is injected. Since it has no structure, even if water is injected with a syringe from the liquid supply port, it is easy to drain water when the syringe is removed, and the syringe is difficult to handle. Therefore, the doctor often needed to transfer the guidewire to a wide container and immerse it in water before using the guidewire. However, according to such a method, it is naturally easy to get filthy, which may cause infection, and it is troublesome. For this,
A more hygienic and less hassle-free guide wire dispenser has been developed. FIG. 1 is a plan view of an aspect of a conventional guide wire dispenser. The guide wire dispenser of this aspect includes a dispenser body 1 made of a tube having a lumen, a guide wire supply part 2 made of a tube having a lumen, and a connector part 3, the connector part being a linear lumen part a4 and a linear shape. A linear lumen part b5 that branches from the middle of the lumen part a and extends parallel to the long axis of the linear lumen part a, and the tip of the linear lumen part b of the connector part and the linear lumen part a. Connect both ends of the dispenser body to one end in the direction opposite to the linear lumen portion b so that the lumen of the dispenser body communicates annularly, and connect the other end of the linear lumen portion a of the connector portion to the rear end of the guide wire supply portion. Are connected so that the lumens of the guide wire supply section communicate with each other. This guide wire dispenser is intended to reduce the guide wire insertion / extraction resistance by linearizing the portion from the guide wire supply part to the dispenser body, but it is necessary to sufficiently lower the insertion / extraction resistance. ,
It was difficult to smoothly insert and remove the guide wire. Further, since the liquid supply port is usually provided in the connector part, there is a problem that when water is injected, water leaks from the tip end port of the guide wire supply part and does not reach the guide wire dispenser body.

[0003]

SUMMARY OF THE INVENTION According to the present invention, the resistance of inserting and withdrawing the guide wire is small, the guide wire can be smoothly taken in and out, and further, water for wetting the guide wire can be easily injected. The purpose of the present invention is to provide a guide wire dispenser that can be used.

[0004]

Means for Solving the Problems As a result of intensive studies to solve the above problems, the present inventors have found that a dispenser main body is more suitable than a straight line from the guide wire supply portion to the dispenser main body. It has been found that the resistance to insertion and withdrawal of the guide wire can be effectively reduced by forming the connecting portion with the connector portion into a stepless shape, and the present invention has been completed based on this finding. That is, the present invention comprises (1) a dispenser main body made of a tube having a lumen, a guide wire supply part made of a tube having a lumen, and a connector part, and the connector part is a linear lumen part a and the linear lumen part a. A linear lumen part b that branches from the middle of the linear lumen part a and extends parallel to the major axis of the linear lumen part a, and the ends of the linear lumen part a of the connector part are connected to both ends of the dispenser body, respectively. It is characterized in that the lumen of the main body is connected in an annular shape, and the rear end of the guide wire supply part is connected to the tip of the linear lumen part b of the connector part so that the lumen of the guide wire supply part is connected. Guide wire dispenser, (2) Dispenser book consisting of tube with lumen , A guide wire supply part consisting of a tube having a lumen and a connector part, the connector part branching from the middle of the curved lumen part and the curved lumen part and along the tangent of the long axis of the curved lumen part. A linear lumen portion that extends, and connect both ends of the dispenser body to both ends of the curved lumen portion of the connector part so that the lumen of the dispenser body communicates annularly and the tip of the linear lumen part of the connector part A guide wire dispenser, characterized in that the rear end of the guide wire supply part is connected so that the lumen of the guide wire supply part is in communication, and (3) the lumen is connected to the middle part of the dispenser body. Item (1) or item (1) with a liquid supply port
A dispenser for a guide wire according to the item (2) is provided. Further, as a preferred embodiment of the present invention,
(4) The guide wire dispenser according to item (1), (2) or (3), wherein the material of the tube of the dispenser body is a fluororesin.

[0005]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, the present invention will be described in detail with reference to the drawings. FIG. 2 is a plan view of one embodiment of the guide wire dispenser of the present invention. The guide wire dispenser of this aspect includes a dispenser body 1 made of a tube having a lumen, a guide wire supply unit 2 made of a tube having a lumen, and a connector unit 3.
The connector part has a linear lumen part a4 and a linear lumen part b5 branching from the middle of the linear lumen part a and extending parallel to the major axis of the linear lumen part a. The both ends of the dispenser body are connected to both ends of the linear lumen portion a so that the lumen of the dispenser body communicates in an annular shape, and the rear end of the guide wire supply portion is connected to the tip of the linear lumen portion b of the connector portion. Connect so that the lumens of the department communicate with each other. In this way, by connecting both ends of the dispenser body to both ends of the linear lumen portion a of the connector part so that the lumen of the dispenser body is communicated in a ring shape without steps, it is branched from one end of the linear lumen part a of the connector part. Compared with a conventional guide wire dispenser in which both ends of the dispenser body are connected to the linear lumen portion b at both ends, the guide wire insertion and withdrawal resistance can be greatly reduced, and the guide wire can be smoothly taken in and out. . FIG.
It is a top view of other modes of a dispenser for guidewires of the present invention. The guide wire dispenser of this aspect includes a dispenser main body 1 made of a tube having a lumen, a guide wire supply part 2 made of a tube having a lumen, and a connector part 3, the connector part having a curved lumen part 6 and a curved shape. A straight lumen portion 7 that branches from the middle of the lumen portion and extends along the tangent to the long axis of the curved lumen portion, and connects both ends of the dispenser body to both ends of the curved lumen portion of the connector portion. So that the lumen of the dispenser body communicates in an annular shape, and the rear end of the guide wire supply part is connected to the tip of the linear lumen part of the connector part so that the lumen of the guide wire supply part communicates. In this way, the curved lumen part is provided in the connector part,
By connecting both ends of the dispenser body to the both ends and communicating the lumen of the dispenser body in a complete ring shape, the guide wire insertion and withdrawal resistance can be further reduced, and the guide wire can be smoothly taken in and out.

The size of the dispenser main body of the guide wire dispenser of the present invention is not particularly limited and can be appropriately selected according to the diameter and length of the guide wire to be used. For example, the inner diameter of the tube is 0.8-7m
m, outer diameter can be 1-8 mm, total length is 300-
It can be 800 mm. Of the commonly used guide wires, the longest one has a total length of about 4,500 mm. The material of the dispenser body is not particularly limited, and examples thereof include polyethylene, polypropylene, polystyrene,
Polyester, nylon, fluororesin, polycarbonate, etc. can be used, but among them, fluororesin has a small resistance when inserting and extracting the guide wire, and can guide and remove the guide wire smoothly. Can be used particularly preferably. Examples of the fluororesin include polytetrafluoroethylene, polychlorotrifluoroethylene, tetrafluoroethylene-hexafluoropropylene copolymer, tetrafluoroethylene-perfluoroalkyl vinyl ether copolymer, tetrafluoroethylene-hexafluoropropylene-perpolymer. Fluoroalkyl vinyl ether copolymer,
Examples thereof include ethylene-chlorotrifluoroethylene copolymer, ethylene-tetrafluoroethylene copolymer, polyvinylidene fluoride and polyvinyl fluoride. Among these fluororesins, polytetrafluoroethylene and tetrafluoroethylene-perfluoroalkyl vinyl ether copolymers are particularly preferable in that the resistance to insertion and extraction of the guide wire is reduced. In the dispenser for a guide wire of the present invention, the dispenser body is preferably made of a transparent material. When the dispenser body is transparent, it is possible to observe the remaining state of air when water is injected from the outside. The inner surface of the dispenser body is preferably in a rough state having fine irregularities rather than being smooth. If the inner surface of the dispenser body is too smooth, the guide wire having a hydrophilic coating may stick to it and make it difficult to move. The guide wire dispenser of the present invention includes a tubular guide wire supply unit 2 that communicates with the dispenser body. FIG. 4 is a cross-sectional view and a perspective view of the guide wire supply unit and the connector of the catheter. The guide wire supply part 2 has a guide wire supply port 8 at its tip, and its rear end is connected to the tip of the linear lumen part of the connector part and communicates with the dispenser body through the connector part. The inner diameter of the guide wire supply port is preferably substantially the same as the outer diameter of the guide wire 9 used. By matching the inner diameter of the guide wire supply port and the outer diameter of the guide wire to be used, they are compatible,
It is possible to smoothly move the guide wire and prevent water leakage from the guide wire supply port. The guide wire supplied from the guide wire supply port is fed into the catheter 11 via the connector 10 of the catheter.

In the dispenser for guide wire of the present invention, the dispenser body can be provided with a liquid supply port communicating with the lumen. It is preferable that the liquid supply port is provided at an intermediate portion of the dispenser body and occupies a position substantially facing the connector portion in the guide wire dispenser. FIG. 5 is a plan view of one embodiment of the guide wire dispenser of the present invention having a liquid supply port. Liquid supply port 12
By providing the connector at a position almost opposite to the connector portion, even if water is rapidly injected, the water does not jump out from the guide wire supply port or the guide wire itself does not jump out due to the flow of water. Air in the dispenser body can be prevented from remaining. In the guide wire dispenser of the present invention, after housing the guide wire having a hydrophilic coating, water can be injected from the liquid supply port to immerse the guide wire in the guide wire. After filling the dispenser with water, the guide wire can be stored from the guide wire supply unit. The water used is preferably sterilized physiological saline, distilled water or the like. By configuring the dispenser body with a transparent material, it is possible to observe the injection state of water from the outside and prevent air from remaining. The liquid supply port is preferably a luer lock or a luer taper. By making the liquid supply port a luer lock or a luer taper, water can be easily injected using a syringe. After injecting water into the dispenser body, the liquid supply port is closed and sealed. There is no particular limitation on the method of sealing the liquid supply port. For example, the liquid supply port can be closed with a stopper, a stopcock can be attached to the liquid supply port, or a check valve can be provided at the liquid supply port. You can In the dispenser for a guide wire of the present invention, a degassing port can be provided in the dispenser body if necessary. The deaeration port is sealed with a hydrophobic porous body that allows air to pass through, but does not allow water to pass, and the air inside the dispenser body is removed through the deaeration port. It is preferable to prevent water leakage. As the hydrophobic porous body that seals the deaeration port, for example, a porous body membrane in which pores are formed in a membrane of a hydrophobic material or a woven fabric having a fine weave of woven hydrophobic fibers can be used. it can. Alternatively, the dispenser body itself may be made of a hydrophobic material, and a deaeration port may be provided by opening pores in the dispenser body with a laser, a neutron beam, or the like.

[0008]

EXAMPLES The present invention will be described in more detail with reference to the following Examples, which should not be construed as limiting the present invention. The guide wire used in the examples is made of stainless steel and coated with polyvinylpyrrolidone, and has a diameter of 0.85 mm and a total length of 2,600 mm.
Was used. In addition, the material of the tube for the dispenser examined was polyethylene (PE), nylon 6 (N
Y6), tetrafluoroethylene-perfluoroalkyl vinyl ether copolymer (PFA), tetrafluoroethylene-hexafluoropropylene copolymer (FE
P) and polytetrafluoroethylene (PTFE). Example 1 (insertion length of guide wire) The guide wire insertability was examined using a guide wire dispenser having a shape shown in FIG. The material of the tube of the dispenser body used was polyethylene, nylon 6, tetrafluoroethylene-perfluoroalkyl vinyl ether copolymer, tetrafluoroethylene-hexafluoropropylene copolymer and polytetrafluoroethylene, and the outer diameter of the tube x The inner diameter is 6 × 4 mm and the total length is 540 mm. The material of the connector is polyethylene, the length of the linear lumen part a is 50 mm, and the length of the linear lumen part b is 20 mm. Also, the material of the guide wire supply part is polyethylene,
The length is 45 mm. Fill the inside of the dispenser for the guide wire with distilled water from the liquid supply port provided in the connector part, and insert the guide wire into the tube at a temperature of 22 ° C. I asked. The measurement was repeated 3 times, and the average value was obtained. When the material of the tube was tetrafluoroethylene-perfluoroalkyl vinyl ether copolymer, the insertion length was 2,535 mm, and when it was polytetrafluoroethylene, the insertion length was 2,153 mm. The results are shown in Table 1 including the case of other materials. Example 2 (guidewire insertion length) The guidewire insertability was examined using a guidewire dispenser having the shape shown in FIG. 3. The material of the tube of the dispenser body used was polyethylene, nylon 6, tetrafluoroethylene-perfluoroalkyl vinyl ether copolymer, tetrafluoroethylene-hexafluoropropylene copolymer and polytetrafluoroethylene, and the outer diameter of the tube x The inner diameter is 6 × 4 mm and the total length is 540 mm. Connector material is ABS
The length of the curved lumen portion is 100 mm, and the length of the linear lumen portion is 60 mm. Also,
The material of the guide wire supply part is polyethylene and the length is 50 mm. Fill the inside of the dispenser for the guide wire with distilled water from the liquid supply port provided in the connector part, and insert the guide wire into the tube at a temperature of 22 ° C. I asked. The measurement was repeated 3 times, and the average value was obtained. When the material of the tube was tetrafluoroethylene-perfluoroalkylvinylether copolymer, the insertion length was 2,550 mm, and when it was polytetrafluoroethylene, the insertion length was 2,468 mm. The results are shown in Table 1 including the case of other materials. Comparative Example 1 (Guidewire Insertion Length) The guidewire insertability was examined using a conventional guidewire dispenser having the shape shown in FIG. The material of the tube of the dispenser used was polyethylene, and the tube had an outer diameter x inner diameter of 6 x 4 mm and a total length of 5
40 mm. The material of the connector is polyethylene, the length of the linear lumen part a is 50 mm, and the length of the linear lumen part b is 20 mm. The material of the guide wire supply part is polyethylene, and the length is 45
mm. Fill the inside of the guide wire dispenser with distilled water from the liquid supply port provided in the connector part, and insert the guide wire into the tube at a temperature of 22 ° C.
An insertion length that allows the guide wire to be smoothly inserted and removed was calculated. The measurement was repeated 3 times, and the average value was found to be 1,652 mm.

[0009]

[Table 1]

From the results shown in Table 1, polyethylene was used as the tube material of the dispenser body, and both ends of the dispenser body were connected to the tip of the linear lumen portion a of the connector portion and one end of the linear lumen portion b, respectively. In the conventional guide wire dispenser of Comparative Example 1 in which the lumen is annularly communicated and the other end of the linear lumen portion a of the connector part is connected to the rear end of the guide wire supply part, the guide wire can be smoothly taken in and out. In contrast to the short insertion length that can be obtained, in the guide wire dispenser of the first and second embodiments of the present invention, the insertion length is long even when the same polyethylene material is used as the tube material of the dispenser body. I understand. Also, when using tubes of the same material,
The guide wire dispenser of Example 2 having the connector portion having the curved lumen portion has a longer insertion length than the guide wire dispenser of the embodiment 1 having the connector portion having the linear lumen portion, It can be seen that forming the lumen portion into a curved shape is effective in reducing the resistance of inserting and withdrawing the guide wire. Further, in the guide wire dispenser having the same connector shape, the insertion length becomes the longest when the material of the tube is a tetrafluoroethylene-perfluoroalkylvinylether copolymer. Example 3 (Water injection into dispenser) The material of the dispenser body was tetrafluoroethylene-
The guide wire dispenser used in Example 2, which is a perfluoroalkyl vinyl ether copolymer, was equipped with a connector part without a liquid supply port, and a liquid supply port with a check valve [manufactured by Vernay] was attached to the middle part of the dispenser body. A guide wire dispenser having the structure shown in FIG. 5 was prepared. In this dispenser for guide wire, 20
Distilled water was injected at a flow rate of ml for 5 seconds, and the amount of distilled water filled in the guide wire dispenser was measured. When the measurement was repeated three times, the ratios to the complete filling were 91%, 92% and 98%, respectively, and the average value was 94%. Comparative Example 2 (Water Injection into Dispenser) Using the conventional guide wire dispenser used in Comparative Example 1, 2 times per second from the liquid supply port provided in the connector part.
Distilled water was injected at a flow rate of 0 ml for 5 seconds, and the amount of distilled water filled in the guide wire dispenser was measured. When the measurement was repeated 3 times, the ratios to the complete filling were 60%, 66% and 51%, and the average value was 59%. From the results of Example 3 and Comparative Example 2, the guide wire dispenser of the present invention in which the liquid supply port is provided in the middle portion of the dispenser body has a higher air flow rate than the conventional guide wire dispenser. It can be seen that the remaining amount is extremely small and the water injection is excellent.

[0011]

According to the dispenser for a guide wire of the present invention, the resistance for inserting and withdrawing the guide wire is small, and the guide wire can be smoothly taken in and out. Further, by providing the liquid supply port at a position facing the connector portion of the dispenser body, water for wetting the guide wire can be easily injected.

[Brief description of drawings]

FIG. 1 is a plan view of one mode of a conventional guide wire dispenser.

FIG. 2 is a plan view of one embodiment of the guide wire dispenser of the present invention.

FIG. 3 is a plan view of another embodiment of the guide wire dispenser of the present invention.

FIG. 4 is a cross-sectional view and perspective view of a guide wire supply unit and a connector of a catheter.

FIG. 5 is a plan view of one embodiment of the guide wire dispenser of the present invention having a liquid supply port.

[Explanation of symbols]

 1 Dispenser main body 2 Guide wire supply part 3 Connector part 4 Straight lumen part a 5 Straight lumen part b 6 Curved lumen part 7 Straight lumen part 8 Guide wire supply port 9 Guide wire 10 Connector 11 Catheter 12 Liquid supply port

Claims (3)

[Claims] 1. A dispenser body made of a tube having a lumen, a guide wire supply part made of a tube having a lumen, and a connector part, wherein the connector part is divided from a straight lumen part a and an intermediate part of the straight lumen part a. A linear lumen part b that branches and extends parallel to the long axis of the linear lumen part a, and connects both ends of the dispenser body to both ends of the linear lumen part a of the connector part to form a lumen of the dispenser body. A guide wire characterized in that the rear end of the guide wire supply part is connected to the tip of the linear lumen part b of the connector part so as to communicate with the lumen of the guide wire supply part so as to communicate in an annular shape. dispenser. 2. A dispenser body composed of a tube having a lumen, a guide wire supply part composed of a tube having a lumen, and a connector part, wherein the connector part is branched from a middle of the curved lumen part and the curved lumen part. And a linear lumen portion extending along a tangent to the long axis of the curved lumen portion, and connecting both ends of the dispenser body to both ends of the curved lumen portion of the connector portion so that the lumen of the dispenser body communicates in an annular shape. The guide wire dispenser is characterized in that the rear end of the guide wire supply part is connected to the tip of the linear lumen part of the connector part so that the lumen of the guide wire supply part is in communication. 3. The dispenser for a guide wire according to claim 1, wherein a liquid supply port communicating with the lumen is provided in an intermediate portion of the dispenser body.