JPH0824314A - Transfusion bag - Google Patents

Abstract

PURPOSE:To provide a transfusion bag which is segmented into plural cells by heat sealing, is capable of separating and storing different medicines in the respective cells of which fused parts are not easily peeled before transfusion operation and which is capable of easily mixing these medicines by complete peeling a heat sealed part at the time of mixing the medicinal liquids in transfusion. CONSTITUTION:This transfusion bag is provided with mouth members 3, 4 for packing or taking out of the medicinal liquids respectively at the top and bottom of a bag-shaped container formed out of a synthetic resin film. This bag-shaped container is provided with the weak sealing part 6 having diamond pattern-shaped and parallel pattern-shaped knurling patterns respectively formed on both outside surfaces thereof in its central part.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention divides a bag-shaped container formed of a thermoplastic synthetic resin film between inner wall surfaces thereof to form weak seal portions having a special knurl pattern on both outer wall surfaces thereof. Thus, the liquid medicine is divided into upper and lower chambers and can be held without being leaked and mixed with each other until the drug solutions contained in the respective chambers are mixed and used for infusion. A liquid transfusing bag capable of easily and aseptically mixing chemical liquids in a plurality of chambers with each other by increasing the internal pressure of at least one partitioned chamber and peeling off the weak seal portion, and providing the liquid transfusion bag It is a thing.

[0002]

2. Description of the Related Art Immediately before infusion of an infusion drug solution, when a plurality of types of drug solutions are mixed to prepare the infusion drug solution, the purpose is to prevent contamination of foreign substances, invasion of various bacteria, etc. during the mixing and preparation work. Hygiene is required, and the inner wall surface of the bag-shaped container made of a synthetic resin film is fused and partitioned, divided into multiple chambers, each chamber is filled with a chemical solution for mixing, and infusion is required. There is known an infusion bag in which the fusion-bonded portion of the partition is sometimes destroyed and the bag-shaped container is made into one chamber so that a plurality of types of drug solutions can be mixed in an aseptic environment.

In the case of the infusion bag of such a type, the fusion-bonded portion of the infusion bag is necessary because it is necessary to surely place the respective mixing medicinal liquids until the separated medicinal liquids are mixed and infused. It should not be easily peeled off in the necessary normal handling steps such as washing, dispensing, sterilization, etc., but when it is intended to be used for the original purpose of infusion by mixing chemicals. Is required to have the property of not breaking the infusion bag itself, that is, the wall of the bag-shaped container, and peeling or breaking only the fused portion.

Various types of infusion bags have been proposed to meet such requirements (for example, Japanese Patent Laid-Open Nos. 63-19149, 1-240469, and 2-4671). JP-A-6-39018
However, in the prior art, a bag-shaped container formed by mixing two types of synthetic resins having low compatibility is used as a means for forming the fusion-bonded portion, and the inner surface of the container is subjected to normal thermal bonding. Typical examples include an easy peel type that does not achieve high adhesive strength by doing so, and a type in which another film is laminated on the inner surface of the infusion bag as a layer having a function of fusing and peeling.

However, the various types of the above-mentioned proposals have a problem in selecting the material used for the container.
That is, it is intended to adjust the fusion strength to a predetermined low adhesive strength range, but it is difficult to always provide a stable peel strength, and the infusion bag is washed and dispensed before the operation of mixing and infusion of a chemical solution. Alternatively, a slight increase in pressure generated in the infusion bag during sterilization or the like often causes partial peeling of the fusion-bonded portion, so that there is a problem that the drug solution is already mixed before the infusion operation.

Further, there is a problem in the fusion method. That is, when a heat seal bar composed of two flat plates is used for forming the fusion-bonded portion, the entire fusion-bonded portion is planarly widened and simultaneously fused by pressure contact with the entire flat plate. Therefore, it is easy to close air bubbles in the fused portion, and there is no escape area for expansion and contraction of the film that occurs during the fusion, and shrinkage wrinkles occur in the fused portion, resulting in uniform heat sealing as the entire fused portion. The state cannot be obtained, and as a result, there is a risk of untimely mixing of the chemicals. Further, when the fusion liquid is mixed, the peel strength tends to vary when the fusion-bonding portion is opened, and stable peel strength cannot be obtained, which causes inconvenience in the chemical mixing operation and deteriorates the appearance of the infusion bag. There was a drawback.

In order to prevent the entrapment of air bubbles and the occurrence of shrinkage wrinkles,
The method of using two heat-sealing bars that have been knurled in a twill pattern and applying heat and pressure has the advantage of obtaining strong heat-sealing strength, and is also useful for manufacturing the infusion bag itself, such as the periphery of the infusion bag. Although it is used, stress concentration based on the twill pattern occurs at multiple points on both sides of the entire heat-sealed part, and in the case of twill patterns that fit with each other, the contact area of the heat-seal part also increases, As a result, the adhesive strength is extremely improved as described above, so that a weak seal having a releasability cannot be obtained as in the object of the present invention.

[0008]

SUMMARY OF THE INVENTION The object of the present invention is to solve the above-mentioned problems in the production of a conventional compartmentalized infusion bag, and to clean, dispense, or sterilize before use for infusion. Even if a slight internal pressure is applied during the process, there is no danger of unnecessary partial peeling of the partition seal on the inner wall surface of the infusion bag. It is an object of the present invention to provide an infusion bag having a weak seal portion, in which the entire seal portion is completely peeled off and the variation of the peeling strength is reduced, and the sealability and the peelability are well balanced.

[0009]

As a result of intensive studies by the present inventors in order to solve the above-mentioned problems, as a result of heating from the outer surface of the container at the time of forming a partition seal part on the inner wall surface of the bag-shaped container, The present invention has been completed based on the knowledge that a solution can be obtained by applying pressure while holding two heated and pressed plates, each of which has been knurled in a specific shape, in a specific positional relationship.

That is, the gist of the present invention is as follows. (First) At least one of the upper and lower ends of a bag-shaped container formed of a synthetic resin film is provided with a mouth member for filling or withdrawing a chemical solution, and the inner surface of the bag-shaped container is weakly sealed to form liquid-tight upper and lower parts. An infusion bag divided into chambers, wherein each outer surface of the weak seal portion is formed with a knurled pattern having a twill shape and a knurled pattern having a flat shape facing each other. Two linear concave-convex structure groups at intervals intersect, which is a mesh pattern formed by the convex structure groups, and the flat knurled pattern is composed of linear concave-convex structure groups at equal intervals and is related to the flat shape. An infusion bag in which each concave structure is formed so as to face the front and back of each convex structure of the one concavo-convex structure group having the above-mentioned cross-section shape. (2) The infusion bag according to the above 1, wherein the parallel linear uneven structure group having a flat knurl pattern has an inclination angle of 30 to 60 degrees with respect to the central axis of the infusion bag. (Third) The infusion bag according to the above-mentioned first, wherein each of the flat concave structure and the cross convex structure which face each other has a triangular cross section. (4) The infusion solution bag according to claim 3, wherein each of the cross-sections of each of the concave structures having the twill shape and the flat shape has a triangular shape with a sheared triangle.

The contents of the present invention will be described in detail below. The synthetic resin film used in the infusion bag according to the present invention may be any of various known synthetic resin films conventionally used in infusion bags, and is not particularly limited. , High-density polyethylene, low-density polyethylene, linear low-density polyethylene, ethylene-vinyl acetate copolymer, in terms of water resistance, moldability, mechanical strength, etc.
Polypropylene, polyvinyl chloride and the like can be preferably used. In addition to a single film, the film forming the infusion bag is preferably a multilayer film in consideration of various functions such as seal part forming property, heat resistance, and rigidity adjusting function. The present invention is to form a weak seal portion for partitioning a plurality of chambers in an infusion bag using such a single or multilayer film.

The weak seal referred to in the present invention is not easily peeled off during various handling of the infusion bag until the infusion work is performed, and the mixing chemical liquid enclosed in each partitioned chamber can be stored as it is. It is a seal, and when mixing the chemicals just before starting the infusion work, if the internal pressure of the compartment is intentionally increased to a predetermined value or more by manual pressure, etc., uniform and stable peeling can be achieved over the entire seal portion on the inner wall surface of the infusion bag. A seal that can be made to mean a seal that is necessary for forming the infusion bag itself, such as the outer periphery of the infusion bag, and that has a fusion strength that is considerably lower than the peel strength of the seal portion that cannot be peeled off. The specific seal strength or the range thereof is appropriately set depending on the shape and size of the infusion bag, the amount of the mixing liquid medicine, and the like.

The weak seal portion according to the present invention requires a relatively high seal strength, but when peeling, a relatively easy sealing state is achieved without affecting other seal portions of the container. Most preferably, setting the seal strength in a desired range is usually a difficult technique as described in the above-mentioned prior art, but the present invention solves this problem by forming a special knurled pattern on both outer surfaces of the seal portion. This is solved by adding a structure group and combining them.

As a material for an infusion bag having such a special knurled concave-convex structure group and capable of forming a weak seal portion, a material having a relatively high rigidity is difficult to use due to the formation of the concave-convex structure. , High density, low density or linear low density polyethylene, polyvinyl chloride other than ethylene-vinyl acetate copolymer are preferred, but low density polyethylene,
A multilayer polyethylene film whose outer wall surface is high-density polyethylene and whose inner wall surface is low-density polyethylene or linear low-density polyethylene is particularly preferably used.

The outer surface of the weak seal portion according to the present invention has a flat knurled pattern composed of linear concave-convex structure groups on one side and two sets of linear concave-convex structure groups on the other side intersect. However, it has a knurled pattern having a mesh-like mesh shape formed by the convex structure group. That is, one surface has a flat mesh shape composed of a group of simple concavities and convexities, while the other surface has a mesh-shaped twill shape in which a convex structure surrounds a concave structure. Further, the flat-shaped concave structure group is back-to-back with a set of twill-shaped convex structure groups, and the former convex-structure group is back-to-back with each gap portion of the latter convex structure group. . It should be noted that concave portions and convex portions forming the twill shape are alternately present in each of the above-mentioned gap portions related to the twill shape.

The back-to-back portion of the flat-shaped concave structure group and the set of twill-shaped convex structure groups has a heating and pressing plate having a convex structure group capable of forming the flat-shaped concave structure group, and the twill. It is a portion that is sealed while being deformed into an uneven shape when sandwiched and pressed by a heating and pressing plate having a concave structure group capable of forming an eye-shaped convex structure group, and is a portion having a relatively high sealing strength. On the other hand, the back-to-back portion of the flat-shaped convex structure group and the twill-shaped gap portion has a heating / pressurizing plate having a concave structure group capable of forming the flat-shaped convex structure group and the twill-shaped gap structure. The gap portion, that is, the portion where the convex structure and the concave structure are alternately present, is the portion that is sealed when sandwiched and pressed by the heating and pressing plate. Since the sealing pressure is not constant, the sealing strength is not constant. The part is relatively easy to peel off. Due to this relationship, a weak seal suitable for the purpose of the present invention can be formed.

The reason why the mesh structure formed by the convex structure group is selected and adopted as the twill shape according to the present invention is that when the mesh groove line is formed by the concave structure group, A heating and pressing plate having a mesh shape consisting of a group of convex structures necessary to form such a mesh-like groove is required, but there is a flat heating shape pressing plate that can be fitted and can be opposed to this. This is because it is not possible to form a flat shape in the seal portion. Also, when both sides are flat and concave and convex are formed back to back, the seal portion of the film is not formed in a mesh shape but becomes a parallel linear seal shape, and once a sealing failure occurs. A non-fused portion is likely to be formed in a straight line, which may cause liquid leakage. Actually, the weak seal having such an outer surface shape relationship has a problem in terms of liquid leakage resistance at the compartment seal portion.

Further, when it is attempted to form a mesh-shaped twill shape having a convex structure on both sides, the heating and pressing plates for forming the twill shape are pressed against each other, and a stable strength having a required strength is obtained. The sealed state cannot be obtained. On the other hand, when both sides are formed into a mesh-shaped twill shape having a concave structure, the stress concentration at the time of pressing between the twill-shape forming heating and pressing plates is too high, and the seal does not have the necessary peelability. I can only get it.

In the present invention, due to the combination of the flat shape and the twill shape as described above, it is taken into consideration that liquid leakage does not occur along the uneven group of flat shapes after the seal portion is formed. When it is parallel to the central axis of the bag, the flat-shaped concavo-convex structure group has the shortest length, and is easily affected by a partial sealing failure.
On the contrary, when it is perpendicular to the central axis, the peel strength at the time of infusion may be too high, and it is difficult to obtain the original weakly sealed state. As a result of various studies on this point, it has been found that in the present invention, it is preferable to adjust the direction of the flat linear concavo-convex structure group within a range of 30 to 60 degrees with respect to the central axis of the infusion bag. If it is less than 30 degrees or more than 60 degrees, the above-mentioned problem is likely to occur.

In the present invention, one of the twill-shaped convex structures is a flat-shaped concave structure as described above, and the gap between the twill-shaped convex structures is back-to-back with the flat-shaped concave structure. However, it is preferable that the concave and convex cross-sectional structures of both heating plates be triangular in order to improve the pressure applied by the heating and pressing plates when back-to-back for forming the seal. Of course, the triangular shape here is not only composed of straight lines, but also slightly rounded and swelled,
On the contrary, it is meant to include things like a triangle that is shriveled,
It does not mean only exact triangles. Therefore, for example, a shape close to a semi-ellipse is also included.

Further, in the case where the cross-sectional shapes of the flat and twill-shaped concave and convex structure portions are made triangular as described above, the twill and flat concave structures are referred to as shear triangular shapes. By doing so, the triangular convex structure portion of the heating and pressing plate becomes a shearing triangular shape, and when the film is sandwiched by this heating and pressing plate, the film pressing force at the apex of the convex structure decreases and the sealing strength is Although weakened, there is an advantage that the deformed force exerted on the film by the sharp apex of the triangular convex portion of the heated film is reduced and the damage of the film is reduced. It is also convenient because a weak seal can be easily obtained.

[0022]

[Function] The two outer surfaces of the partition seal portion of the infusion bag are specified by two kinds of specially shaped knurled patterns, and by having a specific positional relationship with each other, the fitting between the heating and pressing plates becomes appropriate, and the partition chamber The seal strength required for storage can be obtained, and the easily peelable seal can be formed when the chemicals are mixed.

[0023]

【Example】

(Embodiment 1) A description will be given below with reference to the drawings. FIG. 1 is a plan view showing an embodiment of the infusion solution bag of the present invention. In FIG. 1, reference numeral 1 denotes the entire infusion bag, and mouth members 3 and 4 for filling or taking out a liquid medicine are provided above and below a bag-shaped container 2 formed of a synthetic resin film, respectively, and an inner surface of a bag portion 5 is provided. By forming a weak seal portion 6 by sealing in a substantially strip shape, the bag portion 5 is partitioned in a liquid-tight manner to separate the first storage chamber 7 and the second storage chamber 7 from each other.
It is partitioned into a storage room 8.

The shape or structure of both surfaces of the weak seal portion 6 will be described in detail. FIG. 2 is a partially cutaway plan view of the first surface of the weak seal portion 6 in which a flat knurled pattern is formed. The linear convex strip 6a having a triangular cross section has the same triangular cross section. The linear concave portions 6b are formed at equal intervals, and it is not preferable that they are parallel or close to the central axis AA of the infusion bag, or at right angles or close to them. It is most preferable that the angle θ formed by the extension line 6d of the convex 6a and AA is in the range of 30 to 60 degrees from the viewpoint of liquid leakage resistance of the weak seal portion and peeling workability.

The first surface of the weak seal portion 6 is shown in FIG.
The second surface on which the twilled knurled pattern is formed is shown in order to clearly show the relationship between the first surface and the first surface.
Rotate the second surface 180 degrees with the edge 9 of the surface as the axis of rotation,
FIG. 3 is a diagram showing the first and second surfaces side by side, and the lower surface is the first surface and the upper surface is the second surface. The second surface 10a is a ridge having a triangular cross section, and 10b is a concave section having a triangular cross section formed in a portion surrounded by the ridges 10a forming a mesh shape. The shape and structure of this second surface is the same as the convex shape 10
a is arranged at a large number of equal intervals, and two sets of linear concave and convex groups each having a concave shape in each gap intersect each other, and only the intersecting portions of the concave stripes are left in the mesh portion of the convex mesh shape. . Note that among the ridges 10a in FIG. 3, the ridges intersecting the ridges 6b are back-to-back with the ridges 6b shown in FIG. 2, and the recesses 10b in FIG. 3 are the ridges 6a shown in FIG. And back to back.

FIG. 4 is a perspective / partially enlarged view of the twill-shaped surface of FIG. 3, in which the projections 10a are arranged vertically and horizontally to form a net-like shape, and the recesses 10b are formed in each mesh. FIG. 5 is a perspective / partially enlarged view of the flat surface of FIG. 2 or FIG. 3, in which the ridges 6a and the ridges 6b are formed in parallel. Among the ridges 10a shown in FIG. 4, the ridge groups arranged in one direction are back-to-back with the ridges 6b shown in FIG. 5, and the recesses 10b in FIG. 4 are back-to-back with the ridges 6a shown in FIG.

FIG. 6 is a sectional view taken along the line X--X of the weak seal portion 6 of FIG. 2. The upper surface is a flat surface, the convex stripes 6a and the concave stripes 6b are formed, and the lower surface is a twill shape. The surface is formed with the convex stripes 10a and the concave portions 10b, and the convex shape 6 on the upper surface is formed.
a is a recessed portion 10b on the lower surface, and a recessed ridge 6b on the upper surface is formed so as to face back to the protruding ridge 10a. The two opposing films are heat-bonded to each other to form the weak sealing surface 11. The deformation of the weak sealing surface is affected by the uneven structure of the upper surface and the lower surface, and is affected by the heating pressure. In the case of a normally usable weak sealing surface, it is a substantially flat surface. However, the present invention is not limited by the shape of this weak sealing surface.

FIG. 7 is an end view of the weak seal portion 6 of FIG. 2 taken along the line YY of the portion close to the line XX. The position of the concavo-convex structure is slightly displaced, but the end view is shown in FIG. The upper surface is a flat surface, and the ridges 6a and the ridges 6 are
b, the lower surface is a twill-shaped surface, there are convex stripes 10a and concave portions 10b, and the convex shape 6a on the upper surface is the concave portion 10b on the lower surface.
The concave stripes 6b on the upper surface and the convex stripes 10a on the lower surface are formed so as to face each other and back to back. 11 is a weak sealing surface.

FIG. 8 is a cross-sectional end view showing a state in which the heat and pressure plates 12 and 13 are sandwiched and pressed from above and below to form the weak seal part 6.
The concave portion 12b and the convex portion 12a corresponding to the upper convex portion 6a and the concave portion 6b are formed, and the heat press plate 13 has the concave portion 1 corresponding to the lower convex portion 10a and the concave portion b of the weak seal portion 6.
3b and the convex portion 13a are formed. That is, the surfaces of these heating and pressing plates have a flat shape and a twill shape in which the irregularities are reversed, corresponding to the flat shape and the twill shape of the weak seal portion according to the present invention. In addition, 11 is a weak sealing surface.

(Embodiment 2) FIG. 9 is a sectional view of the concave portion 10b having a triangular cross section in FIG.
The case where the concave portion 10c has a triangular truncated shape is shown.
0c is a net-like mesh formed by the ridges 10a. FIG. 10 shows a case where the bottom portion (triangular apex) of the concave portion 6b having a triangular cross section in FIG. 5 is cut to form a claw triangular concave portion 6c. In order to make the concave portion 10b of the weak seal portion shown in FIG. 4 like 10c of FIG. 9 and the concave portion 6b shown in FIG. 5 like 6c of FIG. It is necessary to make the convex shape of the heating / pressurizing plate or the triangular shape of the convex portion into a shearing triangular shape, and by cutting off the apex of the triangle in this way, it was fitted with the concave stripe of the triangular shape in cross section of the other heating / pressurizing plate. In this case, a gap is formed between the concavities and convexities, and the film is not subjected to an excessive deformation stress.

Example 3 Thickness 250 mμ, Folding Diameter 190
A heating / pressurizing plate was used for an infusion bag made of a linear low-density polyethylene tubular film having a diameter of 3 mm and provided with upper and lower mouth members 3 and 4, and a temperature of 123 ° C. and a pressing force of 6
A weak seal portion 6 having a width of 10 mm was formed at Kgf / cm ² and a pressing time of 3.25 seconds. As for the seal pattern, the knurled pattern on one surface is the twill shape shown in FIG. 3 and the other surface is the twill shape shown in the same figure. The angle was 45 degrees.

(Examples 4 to 7) Example 4 was carried out in the same manner as in Example 1 except that the angles of the flat and twill shapes with respect to the central axis were the angles shown in Table 1.

Comparative Examples 1 to 3 The same procedure as in Example 1 was carried out except that the knurled patterns of the heating and pressing plate were changed to the combinations shown in Table 1.

The results of Examples and Comparative Examples are as shown in Table 1 above. Bubbles were visually inspected after the seal portion was formed, and the conductivity of the liquid was measured by putting a chemical solution inside the bag and sealing the seal portion. The stability of the peel strength is visually determined, and the state in which air is blown into the bag from one of the mouth members to peel the seal portion is visually determined. The presence / absence of air bubbles, the presence / absence of liquid conductivity, and the stability of peeling are the uniformity of peeling from the start to the end of peeling. Good), △ (partially defective), ×
It was displayed and evaluated as (Bad).

[0035]

[Table 1]

[0036]

EFFECTS OF THE INVENTION The outer surfaces of the weakly sealed portion of the infusion bag, which is divided by a weak seal at the center of the bag-shaped container, are specified by two kinds of specially shaped knurled patterns so as to establish a specific positional relationship with each other. That is, that is, the knurled pattern on one surface has a mesh shape of a mesh structure formed by convex stripes, and the knurled pattern on the other surface has a flat shape composed of a group of uneven structures, and they are arranged in a specific back-to-back relationship. As a result, a weak seal portion for the purpose of the present invention is formed in which no air bubbles remain on the inner surface of the seal portion and the appearance is good, and high seal strength and easy peeling can be given to the seal portion. Therefore, it is possible to smoothly manage the infusion bag before the infusion work and mix the liquid medicines during the infusion work.

[Brief description of drawings]

FIG. 1 is a plan view showing an embodiment of an infusion bag of the present invention.

FIG. 2 is a partially cutaway plan view of the first surface of the weak seal portion 6.

FIG. 3 is a view showing the first and second surfaces of the weak seal portion 6 side by side.

FIG. 4 is a perspective view and a partially enlarged view of the twilled surface in FIG.

5 is a perspective view and a partially enlarged view of the flat surface in FIG.

6 is an end view of the weak seal portion 6 of FIG. 2 taken along line XX.

7 is a sectional view of the weak seal portion 6 of FIG. 2 taken along line YY.

FIG. 8 is a cross-sectional end view in a state of being sandwiched and pressed by heating and pressing plates 12 and 13 for forming a weak seal portion 6.

FIG. 9 is a perspective view and a partially enlarged view of a bottom portion (triangular apex) of a recess 10b having a triangular cross section in FIG. 4 to obtain a sheared triangular recess 10c.

FIG. 10 is a perspective view and a partially enlarged view of a concave portion 6c having a triangular cross section in FIG.

[Explanation of symbols]

 1 Infusion bag 2 Bag-like container 3 Mouth member 4 Mouth member 5 Bag part 6 Partially cutaway plan view of weak seal part 6a Convex 6b Recess 6c Recess 6d Extension line of convex 6a 7 First storage chamber 8th 2 storage chamber 9 weak seal part edge 10a convex line 10b concave part 10c concave part 11 weak sealing surface 12 heating and pressing plate (upper) 12a convex part 12b concave part 13 heating and pressing plate (lower) 13a convex part 13b concave part

 ─────────────────────────────────────────────────── ─── Continuation of front page (72) Inventor Nobuyuki Tanaka 3-2 Chidori-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa Akira Kawasaki Plastic Research Laboratory

Claims (4)

[Claims] 1. A bag member made of a synthetic resin film is provided with a mouth member for filling or withdrawing a chemical solution on at least one of the upper and lower ends of the bag container, and the inner surface of the bag container is weakly sealed to be liquid-tight in upper and lower parts. An infusion bag divided into a plurality of chambers, wherein each outer surface of the weak seal portion is formed with a knurled pattern in a twill shape and a flat shape in opposition to each other, and the knurled pattern in a twill shape is Two equally-spaced linear concave-convex structure groups intersect each other, which is a mesh pattern formed by the convex structure groups,
The flat knurled pattern is composed of linear concave-convex structure groups at equal intervals, and each concave structure related to the flat shape is formed so as to face front and back with each convex structure of the one concave-convex structure group related to the cross-shaped shape. An infusion bag characterized by being used. 2. A group of parallel linear concave-convex structures having a flat knurled pattern in the range of 30 to 60 with respect to the central axis of the infusion bag.
The infusion bag according to claim 1, having an inclination angle of degrees. 3. The infusion bag according to claim 1, wherein each of the flat-shaped concave structure and the cross-shaped convex structure which face each other has a triangular cross-section. 4. The infusion bag according to claim 3, wherein each cross-section of each of the concave structures having the cross-shaped shape and the flat-shaped shape has a triangular shape with a sheared triangle.