JPH0767837A - Cornea endothelium photographing device - Google Patents

Cornea endothelium photographing device

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Publication number
JPH0767837A
JPH0767837A JP5241986A JP24198693A JPH0767837A JP H0767837 A JPH0767837 A JP H0767837A JP 5241986 A JP5241986 A JP 5241986A JP 24198693 A JP24198693 A JP 24198693A JP H0767837 A JPH0767837 A JP H0767837A
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Japan
Prior art keywords
light
slit
receiving element
light receiving
reflected light
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Pending
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JP5241986A
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Japanese (ja)
Inventor
Kuniomi Abe
Yoshizo Ikegami
Masahiko Konagaya
正彦 小長谷
吉藏 池上
國臣 阿部
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Konan:Kk
株式会社コーナン
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Application filed by Konan:Kk, 株式会社コーナン filed Critical Konan:Kk
Priority to JP5241986A priority Critical patent/JPH0767837A/en
Priority claimed from US08/296,031 external-priority patent/US5471261A/en
Publication of JPH0767837A publication Critical patent/JPH0767837A/en
Application status is Pending legal-status Critical

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Abstract

PURPOSE:To provide a cornea endoshelium photographing device constituted so that an endothelium reflected light being much than an epithelium reflected light and a photographing adaptive position can be detected, when the eyeball surface is subjected to slit illumination and focusing is executed be using a cornea reflected light, at the time of enlarging and photographing a cornea endothelium cell of an eye to be examined. CONSTITUTION:When the eyeball surface 2 is subjected to slit illumination, and based on an illuminating light, an endothelium image of a part to be examined is formed in a focused state on the image receiving surface 22 of a television camera 23 through an enlarging/photographing optical system, a focusing detection photodetector 18 is set to a position for photodetecting an endothelium reflected light or an epithelium reflected light of a slit light on an optical axis 141 passing through an objective lens 15. A photodecting state of the slit light of this photodetector 18 is set so that a cornea endothelium reflected light can be detected surely, and a photographing adaptive position is detected at the time of advancing a photographing system 3 by a slit diaphragm 17 in front of the element and a detection slit diaphragm 7 in front of an illumination lamp 4, and raising the amplification gain of the element by catching a rise of an epithelium reflecting signal in the element concerned 18, etc.

Description

【発明の詳細な説明】 DETAILED DESCRIPTION OF THE INVENTION

【0001】 [0001]

【産業上の利用分野】この発明は、被検者の眼球の角膜内皮細胞を拡大観察乃至拡大写真撮影するための角膜内皮撮影装置に関する。 BACKGROUND OF THE INVENTION This invention relates to corneal endothelium photographing device for magnifying observation to enlarge photographed corneal endothelium of an eye of a subject.

【0002】 [0002]

【従来の技術】コンタクトレンズの影響を見るためや、 And to see the impact of the Prior Art Contact lenses,
白内障手術の術前術後の診療に角膜内皮細胞の状態を観察する必要があり、従来から、被検者の眼球の角膜内皮細胞の拡大観察乃至拡大写真撮影のため、被検者の眼球面に対し顕微鏡の対物レンズを非接触型又は接触型として、スリット照明光を眼軸に対し斜方向から被観察部に向け照射し、その角膜からの反射光を拡大して観察したり、スリット照明光の角膜内皮からの反射光の位置を検出することより所謂三角測量法の原理で角膜内皮にピントの合う撮影適合位置を検出し、被検部の角膜内皮細胞をテレビカメラ等により撮影するようにした装置が用いられている。 Must observe the state of the corneal endothelial cells Preoperative Postoperative care cataract surgery, conventionally, for magnifying observation to magnified photograph of the corneal endothelium of an eye of a subject, the eye surface of the subject as a non-contact type or contact type microscope objective lens with respect to the slit illumination light is irradiated toward the object of observation from an oblique direction with respect to the axial, or observed by enlarging the reflected light from the cornea, slit illumination the principle of the so-called triangulation method from detecting the position of the reflected light from the corneal endothelium optical detecting the photographing matching position where focus is achieved in the corneal endothelium, to shoot the corneal endothelial cells of the subject part by a TV camera or the like devices are used you.

【0003】ところが、これらの従来の装置では、テレビカメラを付設した顕微鏡架台をジョイスティック等の操作部材を用いて手動で本体である上記架台を前後方向に移動せしめて角膜内皮の合焦を行っていたが、被検部をスリット照明してその角膜反射光を用いて合焦するに際し、上皮反射が強くて内皮反射が弱くその差が大きいため、内皮反射光検出が困難で角膜内皮の合焦がしにくいという問題があった。 [0003] However, in these prior art devices, have been manually focusing corneal endothelium moved the frame is the main body in the longitudinal direction by using the operation member such as a joystick microscope stand that attaching a television camera It was, but upon focused by using the corneal reflection light by the slit illuminating the object part, strong epithelial reflected due to the large the difference weak endothelium reflection, burnt if the corneal endothelium is difficult endothelial reflected light detection there is a problem that hard to have. そのため、被検部の角膜内皮細胞に合焦せしめるまで相当の手間と習熟を必要とした。 Therefore, it required the skill and considerable time until allowed to focus on the corneal endothelial cells of the subject part.

【0004】本発明は、上記の点に鑑みてなされたものであって、手間や習熟を必要とせず、被検者頭部をアゴ台に固定した後、被検者に被検眼で固視標を固視せしめて機械を作動させるだけで、手動の場合は勿論自動的にも、容易且つ確実に角膜内皮反射光を検出して撮影適合位置を検出し、被検部の角膜内皮細胞の拡大観察乃至拡大撮影を行うことのできる装置を提供することを目的とする。 [0004] The present invention was made in view of the above, without the need for labor and skill, after fixing the jaw base to the subject head fixation in the subject's eye to the subject only to operate the machine allowed fixation the target, of course automatically even in the case of manual, easily and reliably detect the shooting matching position by detecting the corneal endothelial reflected light, the corneal endothelial cells of the subject part and to provide an apparatus capable of performing magnifying observation to magnified photography.

【0005】 [0005]

【課題を解決するための手段】上記目的を達成するために、本発明の角膜内皮撮影装置においては、被検眼の眼球面をスリット照明する照明系と、眼球面を照射したスリット照明光に基づき被検部の拡大像を結像させるための拡大撮影光学系と、該拡大撮影光学系の結像面に角膜内皮像が合焦状態で結像するとき少くとも対物レンズを介してスリット光の角膜内皮反射光又は角膜上皮反射光を受光する位置に設定された合焦検知用受光素子と、合焦検知用受光素子におけるスリット光の受光状態を制御して角膜内皮反射光の検出能力を向上させるための受光状態制御手段と、これらの装置本体を、角膜内皮合焦位置に来るように被検眼方向に移動させる手段とから構成されている。 To achieve the above object, according to the solution to ## in the corneal endothelium photographing apparatus of the present invention includes an illumination system for slit illumination eye surface of the eye, based on slit illumination light irradiating the eyeball surface an enlarged image taking optical system for forming an enlarged image of the object part, the slit light via at least an objective lens when a cornea endothelium image on the imaging surface of the enlarged photographing optical system is imaged in focus state a focus detection light receiving element is set to a position for receiving the corneal endothelial reflected light or cornea epithelium reflected light, by controlling the light receiving state of the slit light in the focus detecting light-receiving element improved detection capability of corneal endothelium reflected light a light receiving state control means for, these apparatus body, to come to the corneal endothelium focusing position is composed of a means for moving the eye direction.

【0006】上記装置の合焦検知用受光素子における受光状態制御手段としては、該合焦検知用受光素子の前方に、スリット照明光による角膜反射像の長手方向に長いスリット状絞りを配置することが得策である。 [0006] As the light receiving state control means in focus detection light receiving element of the device, in front of 該合 focus detection light receiving element, placing a long slit-like aperture in the longitudinal direction of the image of corneal reflection by the slit illuminating light There is a good idea.

【0007】また、合焦検知用受光素子における受光状態制御手段としては、該合焦検知用受光素子が先に検出する上皮反射光検出信号で、上記照明系のスリット照明の光量を上げるようにしたり、同じく該上皮反射検出信号で、該合焦検知用受光素子の受光感度を上げるようにして角膜内皮反射光の検出能力を向上させることも効果的である。 Further, as the light receiving state control means in the focus detecting light receiving element, epithelial reflected light detection signal 該合 focus detection light receiving element is detected first, so as to increase the quantity of slit illumination of the illumination system or, like in epithelial reflected detection signals, it is also effective for improving the detection capability of corneal endothelium reflected light so as to increase the light receiving sensitivity of 該合 focus detection light receiving element.

【0008】また、合焦検知用受光素子における受光状態制御手段として、該合焦検知用受光素子の前方に、スリット照明光による角膜反射像の長手方向を圧縮する光学系を配置することもできる。 Further, as the light receiving state control means in the focus detecting light receiving element, in front of 該合 focus detection light receiving element may be disposed an optical system for compressing the longitudinal direction of the image of corneal reflection by the slit illuminating light .

【0009】さらに、合焦検知用受光素子における受光状態制御手段としては、上記スリット照明光学系において、撮影用のスリット状絞りと別個に、該撮影用スリット状絞りより狭巾の検出用スリット状絞りを設けることも有効である。 Furthermore, as the light receiving state control means in the focus detecting light receiving element, in the slit illumination optical system, separately from the diaphragm slit for imaging, detecting slit-like Semahaba from the imaging slit-shaped aperture it is also effective to provide the aperture.

【0010】 [0010]

【作用】この装置では、照明系によりスリット照明された眼球面からの反射光に基づき、拡大撮影光学系により被検部の内皮の拡大像が結像される。 SUMMARY OF In this apparatus, based on the reflected light from the eyeball surface which is slit illuminated by the illumination system, the magnified image of the endothelium of the object part is imaged by the enlarged image taking optical system. この場合、図2の所謂三角測量法を用いた受光素子による角膜の合焦原理図が示すように、手動又は自動的に撮影系を被検眼方向に前進せしめて撮影系と被検眼との相対的移動Emがあると、照明光軸12より投影レンズ13を通して被検者の角膜2に投影された上下に長いスリット照明光は、角膜上皮 In this case, as the focus principle diagram of the cornea by the light receiving element using a so-called triangulation method of FIG 2, manually or automatically shooting system brought forward the eye direction imaging system relative to the eye specifically the mobile Em is a long slit illumination light vertically projected on the cornea 2 of the subject through the projection lens 13 from the illumination optical axis 12, the corneal epithelium
2a面の反射部位2ar'で反射して対物レンズ15を介してスリット状の上皮反射光2ar が角膜反射光の動きを表わす矢印Crm 方向に移動するとともに、上皮を通過した照明光は照明光軸12上で角膜内皮2b面の反射部位2br'で反射して同じく対物レンズ15を介してスリット状の内皮反射光2br が、上記スリット状の上皮反射光2ar に続いて(小間隙をおいて)隣接状態で上記Crm 方向に移動する。 Reflected by the reflecting portion 2ar 'of 2a surface through the objective lens 15 with a slit-like epithelial reflected light 2ar moves in the arrow Crm direction representing the movement of the cornea reflection light, illumination light passing through the epithelium illumination optical axis 12 on the reflective to also slit-like endothelial reflected light 2br through the objective lens 15 by the reflecting portion 2br 'of the corneal endothelium 2b surface with, following the slit-like epithelial reflected light 2ar (at a small clearance) It moves in the Crm direction adjacent state. そして、テレビカメラ23の受像面(CCD受光面: Then, the image-receiving surface of the TV camera 23 (CCD light-receiving surface:
図1参照)22に角膜内皮像が合焦状態で結像するときに図2の内皮反射光2br(又は上皮反射光2ar)が位置する場所へ設定された受光素子18に対し、上記内皮反射光2br Corneal endothelium images at focus state with respect to the light receiving element 18 that endothelial reflected light 2br in FIG. 2 (or epithelial reflected light 2ar) is set to the location that is located at the time of imaging in Figure 1 reference) 22, the endothelium reflection light 2br
(又は上皮反射光2ar)が入射すると、被検眼の角膜内皮はテレビカメラの受光面に合焦状態となり、テレビカメラ23より図示しないモニターを介して拡大された角膜内皮細胞像を観察乃至写真撮影することができる。 (Or epithelial reflected light 2ar) when the incident, corneal endothelium of the eye becomes focused state to the light receiving surface of the television camera, observation or photographing of corneal endothelium images that are magnified through a monitor (not shown) from the TV camera 23 can do.

【0011】本装置の撮影位置検出に際して、合焦検知用受光素子18で角膜内皮反射光が検出されるとき、撮影系の前進に伴って、矢視Cで見ると、受光素子18の前を上皮反射光2ar に続いて内皮反射光2br が横切って受光素子18から上皮反射と内皮反射の受光信号が得られるが、上皮反射に較べて隔段に弱い内皮反射は、合焦検知用受光素子18の前面に、スリット照明光による角膜反射像の長手方向に長いスリット状絞りを配置すると、図3 [0011] In the photographing position detection of the device, when the corneal endothelial reflected light at the focus detection light receiving element 18 is detected, with the advancement of the imaging system, when viewed in arrow C, and before the light-receiving element 18 While receiving signals following the epithelium reflected light 2ar epithelial reflected endothelial reflected from the light receiving element 18 across endothelial reflected light 2br obtain a weak endothelium reflected 隔段 compared to epithelium reflection is focused detection light receiving element 18 in front of, placing a long slit-like aperture in the longitudinal direction of the image of corneal reflection by the slit illumination light, 3
に示すように、受光素子前にスリット状絞りの無い場合に比べて内皮反射の山のピークが明瞭となり、近接した上皮反射との分離を良くすることができ、角膜内皮反射光を確実に検出することができる。 As shown in, the peak of the mountain endothelium reflection as compared with the case before the light-receiving element without the slit diaphragm-like becomes clear, it is possible to improve the separation between adjacent epithelial reflected reliably detect corneal endothelial reflected light can do.

【0012】また、合焦検知用受光素子18で、上皮反射光2ar に続いて内皮反射光2br が検出されるとき、該受光素子18で時間的に先に検出する明るい上皮反射受光信号の立上りをとらえ、これをトリガーに、照明ランプ電圧UPのスイッチングや照明光学系内の絞り開放などによりスリット照明光量を上げ明るくしたり、或いは、受光素子18のアンプのゲイン切替をスイッチングすることにより、受光素子18における内皮反射受光信号のゲインを上げることができ(図4参照)、角膜内皮反射光を確実に検出することができる。 Further, in the focus detection light receiving element 18, when following the epithelium reflected light 2ar endothelial reflected light 2br is detected, rising bright epithelial reflected light signal detected earlier in time by the light receiving element 18 the captured, to trigger this, or brighten up the slit illumination light amount due open aperture in the switching and illumination optical system illuminating lamp voltage UP, or by switching the gain switching amplifier of the light receiving element 18, the light receiving can increase the gain of the endothelium reflection light receiving signal in the element 18 (see FIG. 4), it is possible to reliably detect the corneal endothelial reflected light.

【0013】一方、上記合焦検知用受光素子18の前方に、スリット照明光による角膜反射像の長手方向を圧縮する光学系(例えばシリンドリカルレンズ)を配置することにより、スリット状の角膜反射像の全体を受光素子で無駄なく受けることができ、該受光素子18における角膜内皮反射光の検出能力を上げることができる。 Meanwhile, in front of the focus detection light receiving element 18, by arranging the optical system (e.g., a cylindrical lens) for compressing the longitudinal direction of the image of corneal reflection by the slit illumination light, the slit-like cornea reflection image the whole can be received without waste by the light receiving element, it is possible to enhance the detection capability of the corneal endothelial reflected light at the light receiving element 18.

【0014】さらに、上記スリット照明光学系において、撮影用のスリット状絞りと別個に、該撮影用スリット状絞りより狭巾の撮影位置検出用のスリット状絞りを使用すると、従来の撮影用と検出用とを兼用したスリット状絞りに比較してより狭い巾のスリット状絞りを撮影位置検出用に用いることができ、図2の矢視Cによる受光素子と角膜反射光との関係を表わした図5(a),(b) が示すように撮影用スリット光により照明した撮影時には、スリット状絞りで巾を狭めてある受光素子の受光エリア18a に比し充分広い巾の角膜反射光2ar, 2brが得られ従来より広い視野で撮影することができる一方、検出用スリット光により照明した検出時には、上記受光素子の受光エリア18a より狭い目の巾の角膜反射光2ar, 2br Furthermore, in the slit illumination optical system, separately from the diaphragm slit for photography, using a slit-shaped aperture for capturing the position detection of Semahaba from the imaging slit-shaped aperture, detection and conventional for photographing compared with the slit-like aperture and also serves as a use to be able to use a slit-like aperture of narrower width for shooting position detection, showing the relationship between the light receiving element and the cornea reflection light by the arrow C in FIG. 2 FIG. 5 (a), (b) at the time of shooting illuminated by the photographing slit light shows, sufficiently wide width of the cornea reflection light 2ar than the light receiving area 18a of the light receiving element that is narrowing the width by a slit-shaped aperture, 2br while it is possible to shoot a wide field of view than conventionally obtained, upon detection that illuminated by detecting slit light receiving area 18a narrower eye width of the corneal reflection light 2ar of the light receiving element, 2br
が得られ、従来より位置精度良く角膜内皮反射を検出して撮影位置を検出することがてきる。 Is obtained, Tekiru is possible to detect the imaging position to detect the position accurately corneal endothelial reflected conventionally. なお、図5での矢印は、撮影系を被検眼方向に前進せしめるときの角膜反射光2ar, 2brの移動方向を示しており、また、図5における角膜上皮反射光の像2ar 及び角膜内皮反射光の像2b The arrows in Figure 5, the corneal reflected light 2ar when allowed to advance the imaging system onto the eye direction indicates a moving direction of the 2br, also the image 2ar and corneal endothelial reflected corneal epithelial reflected light in FIG. 5 image 2b of the light
r は、本当は、生体からの反射で図6に示すように不明瞭な輪郭をしているが、図5では説明をしやすくする目的で簡略化して表示している。 r is truth, although the unclear contours as shown in FIG. 6 by the reflection from the living body, are displayed in a simplified manner in order to facilitate the explanation in FIG.

【0015】 [0015]

【実施例】本発明の実施例を添付の図面に基いて説明する。 Examples of EXAMPLES The invention will be described with reference to the accompanying drawings. 図1は、上記実施例の光路図を示す。 Figure 1 shows an optical path diagram of the embodiment.

【0016】図1において、被検眼1の眼球面2をスリット照射する照明系と、眼球面2に対面して眼球面を照射したスリット照明光に基づきテレビカメラ23により被検部の拡大観察乃至拡大写真撮影を行えるようにした拡大撮影光学系とからなり、且つ、該拡大撮影光学系の光路の一部を延長して被検部の角膜内皮反射(又は角膜上皮反射)を検出して撮影適合位置を検出するための合焦検知用受光素子18を備えた撮影系3が示されており、該撮影系3は、被検眼1の眼軸方向に図示しない駆動手段によって移動させられる。 [0016] In FIG 1, an illumination system which irradiates slit eyeball surface 2 of the eye 1, enlarged observation to the test region by the TV camera 23 based on slit illumination light facing the eyeball surface 2 is irradiated with the eyeball surface consists was allow an enlarged photograph enlarged photographic optical system, and, corneal endothelial reflected object part by extending a portion of the optical path of the enlarged image taking optical system (or the corneal epithelium reflection) detected and photographed matching position and photographing system 3 having a focusing detection light receiving element 18 for detecting the indicated, the imaging system 3 is moved by a driving means (not shown) in the axial direction of the eye 1.

【0017】眼球面2の被検部の照明光源として、拡大撮影光学系のフォーカシング時に用いる照明ランプ4 [0017] As the illumination light source of the subject portion of the eyeball surface 2, the illumination lamp 4 used at the time of focusing of the enlarged image taking optical system
と、角膜内皮細胞の拡大写真撮影時に用いるストロボ放電管8とが、それぞれの発する光が照明光軸12より投影レンズ13を介して被検眼1の被観察面である角膜2を、 When the strobe discharge tube 8 to be used during expansion photography of the corneal endothelial cells, corneal 2 each emit light is the observed surface of the eye 1 via the projection lens 13 from the illumination optical axis 12,
眼軸に対して斜方向から所定角度で照射するように、ストロボ放電管8は照明光軸12上の所定位置に、また、照明ランプ4は照明光軸12上のハーフミラー11を介して照明光軸12と直角方向の光軸上に設けられている。 So as to emit at a predetermined angle from an oblique direction with respect to axial, the strobe discharge tube 8 at a predetermined position on the illumination optical axis 12, also the illumination lamp 4 through the half mirror 11 on the illumination optical axis 12 Lighting It is provided on the optical axis 12 and perpendicular to the optical axis.

【0018】そして、照明ランプ4の発する光は集光レンズ5による集束位置に、後述する合焦検知用受光素子 [0018] Then, light emitted from the illumination lamp 4 in the focusing position of the condenser lens 5, a focusing detection light receiving element which will be described later
18前面のスリット絞り17に対応した狭い所定巾の検出用スリット絞り7が設けられる一方、ストロボ放電管8の発する光は集光レンズ9による集束位置に、広い視野で撮影できるようにするための所定の稍広巾の撮影用スリット絞り10が設けられ且つ、検出用スリット7の手前の照明ランプ4の光軸上に可視光カットフィルター6が設けられて、赤外線反射・可視光透過の上記ハーフミラー 18 while detecting slit aperture 7 of narrow predetermined width corresponding to the front of the slit diaphragm 17 is provided, the light emitted by the strobe discharge tube 8 for focusing position of the condenser lens 9, to allow imaging with a wide field of view predetermined 稍広 width imaging slit aperture 10 is provided and the visible light cut filter 6 is provided on the optical axis in front of the illuminating lamp 4 of the detection slit 7, the half mirror infrared reflecting and visible light transmission
11で照明ランプ4の光の赤外光のみが反射して眼球面2 11 only infrared light of the light of the illuminating lamp 4 is reflected by the eyeball surface 2
に投影される一方、ストロボ放電管8の可視光は該ハーフミラー11を透過して眼球面2に投影されるようになっている。 While it projected in visible light of the strobe discharge tube 8 is adapted to be projected into the eye surface 2 passes through the half mirror 11.

【0019】また、上記照明系の照明光軸12と被検眼の眼軸2 1を挾んで反対側には、眼球面2に対する照明ランプ4又はストロボ放電管8による斜めのスリット状照明光線の角膜からの反射光を受けて被観察部の角膜内皮細胞像を、テレビカメラ23の受像面(CCD受光面)22に結像せしめて拡大観察乃至拡大写真撮影するための拡大撮影光学系が設けられ、テレビカメラ23の受像面22に角膜内皮像が合焦状態で結像するときに、該光学系の光路の一部を延長した位置に設定された合焦検知用受光素子 Further, on the opposite side of the axial 2 1 of the eye and the illumination optical axis 12 of the illumination system, the cornea of the oblique slit-shaped illumination light by the illumination lamp 4 or the strobe discharge tube 8 to the eyeball surface 2 the corneal endothelial cell image of the observed section receives the reflected light from the enlarged photographic optical system for magnifying observation to enlarge photographed allowed imaging is provided on the image receiving surface (CCD light-receiving surface) 22 of the TV camera 23 when the corneal endothelium image on the image receiving surface 22 of the TV camera 23 is imaged by the focus state, focus is set to the extended position a part of the optical path of the optical system focusing detection light receiving element
18が、撮影系3の前進に伴って該焦受光素子の前面を移動する角膜内皮反射光(又は角膜上皮反射光)を検知するようになっている。 18 is adapted to detect a corneal endothelial reflected light (or corneal epithelial reflected light) that moves the front of the focal light receiving element in accordance with the forward movement of the imaging system 3.

【0020】すなわち、被検眼1の眼軸2 1を挾んで照明系の照明光軸12と対称位置にある拡大撮影光学系の光軸 [0020] That is, the optical axis of the enlarged image taking optical system in the illumination optical axis 12 and symmetrical position of the illumination system across the axial 2 1 of the eye 1
14 1上の所定位置に、眼球面側に対物レンズ15が、また該対物レンズ15と所定距離をおいてハーフミラー(赤外光透過・可視光反射)16が、該光軸14 1と所定角度交叉して眼球面からの前記照明光の反射光による像光線を上記眼軸2 1の略軸線上の所定位置に直交するように折曲げるべく配置され、該ハーフミラー16により反射した像光線は光軸14 2上を中間結像面に位置する視野絞り19及び拡大レンズ20を通って上記眼軸2 1方向と45°交叉したミラー21により拡大像光線のうちストロボ光による撮影用スリット光の可視光は全反射して、折曲げられた光軸14 14 in position on the 1, the objective lens 15 on the eyeball surface side and the objective lens 15 and the half mirror at a predetermined distance (infrared transmission and visible light reflection) 16, optical axis 14 1 and a predetermined an image light by the reflected light of the illumination light from the angle crossed to the eyeball surface is arranged to bending so as to be perpendicular to the predetermined position of the substantially axial line of the axial 2 1, the image light reflected by the half mirror 16 photographing slit light by the strobe light out of the enlarged image rays by the optical axis 14 2 top through the field stop 19 and the magnifying lens 20 is located on an intermediate image plane the axial 2 1 direction 45 ° crossover mirrors 21 of visible light is totally reflected, folded optical axis 14
3上に設けられたテレビカメラ23の受像面(CCD受光面)22に入射する一方、撮影位置検出用スリット光の赤外光は上記光軸14 1上の光路を延長して上記対物レンズ 3 While entering the image receiving surface (CCD light-receiving surface) 22 of the TV camera 23 provided on the photographing position of the detection slit light infrared light the optical axis 14 1 on the objective lens by extending the optical path of the
15による角膜反射像光線の結像位置に設けられた合焦検知用受光素子18に入射するようになっている。 It is incident on the focusing detection light receiving elements 18 provided at an imaging position of the corneal reflection image light by 15. そして、 And,
対物レンズ15及び拡大レンズ20によりテレビカメラ23の受像面22に角膜内皮像が合焦状態で結像するときに、スリット状の内皮反射光は合焦検知用受光素子18前方の角膜反射像の長手方向に長いスリット絞り17により近接する上皮反射との分離を良くして(図3参照)入射するとともに、上記照明ランプ4の発する光の集束位置のスリット絞り7により巾を挾くして受光素子18の受光エリア The objective lens 15 and the magnifying lens 20 when the cornea endothelium image on the image receiving surface 22 of the TV camera 23 is imaged by the focus state, the slit-like endothelial reflected light focusing detection light receiving element 18 in front of the cornea reflection image and better separation of the epithelium reflection closer to the longitudinal long slit diaphragm 17 together (see FIG. 3) enters, 挾 the width by slit diaphragm 7 of the converging position of the light emitted by the illumination lamp 4 comb receiving element 18 light-receiving area of
18a に入射する検出用スリット光により(図4参照)、 By detecting slit light incident on 18a (see FIG. 4),
該受光素子18で位置精度良く確実に角膜内皮反射光を検出して装置の撮影適合位置を検出することができる。 Shooting matching position of the detection to the equipment location accuracy reliably corneal endothelial reflected light at the light receiving element 18 can be detected.

【0021】なお、この際、合焦検知用受光素子18からの最初に来る上皮反射受光信号の立上りをとらえて、照明ランプ4の電圧UPのスイッチングによりスリット照明光量を上げることにより、暗くて検出しにくい内皮反射光を明るくして上皮反射と内皮反射の強度差を無くして内皮反射光を確実に検出できるようにしたり、また、同じく上皮反射受光信号の立上りをとらえ受光素子18のアンプのゲイン切替をスイッチングして受光素子の感度を高めて内皮反射光を確実に検出できるようにすることも可能であり、さらに、受光素子18の前方にシリンドリカルレンズを配置してスリット状の角膜反射像の全体を受光素子で無駄なく受けて角膜内皮反射検出を効率よく行うことも可能であるなど、合焦検知用受光素子におけるスリット光の受光状 [0021] At this time, captures the rise of first come epithelium reflected light reception signal from the focus detection light receiving element 18, by increasing the slit illumination light amount by the switching of the voltage UP of the illuminating lamp 4, dark detection or to brighten hardly endothelial reflected light by eliminating the intensity difference epithelial reflected endothelial reflected to reliably detect endothelium reflected light, also, the amplifier gain of the light receiving element 18 also captures the rise of epithelial reflected light reception signal it is also possible to switch by switching to enhance the sensitivity of the light receiving element to be reliably detected endothelium reflected light, further, the image of corneal reflection slit by arranging the cylindrical lenses in front of the light receiving element 18 including the entire it is possible to efficiently perform the corneal endothelium reflection detection receives without waste by the light receiving element, like receiving the slit light in the focus detecting light receiving element を種々の手段を用いて制御して角膜内皮反射光の検出能力を向上させ、確実に角膜内皮反射光を検出するようにして装置の撮影適合位置を検出することができる。 The controlled using various means to improve the detection capability of the corneal endothelial reflected light, it is possible to reliably detect the shooting matching position of the to apparatus to detect the corneal endothelial reflected light.

【0022】上記撮影系3の撮影適合位置への設定、すなわちテレビカメラ23の受像面22における角膜内皮像の合焦に当っては、手動の場合はジョイスティック等の操作部材を用いて撮影系3を搭載した架台を被検眼方向に移動せしめて、上記合焦検知用受光素子18からの合焦信号を用いて表示ランプやブザーにより、装置の撮影適合位置設定を容易に行うことができる一方、撮影系3を搭載した架台を図示しない前眼部撮影装置でアライメント光が前眼部像の所定領域に入った信号など任意の信号で、待機位置から被検眼方向に前進せしめて、上記合焦検知用受光素子で上皮反射を検出した後内皮反射を検出するとき架台の前進を停止せしめるようにして、撮影適合位置を自動的に検出できるようにすることができる。 The setting of the shooting matching position of the imaging system 3, i.e. TV hitting the focus of the corneal endothelium image in the image receiving plane 22 of the camera 23, the imaging system 3 for manual using the operation member such as a joystick equipped with a gantry in moved the eye direction, the display lamp or buzzer with a focusing signal from the focusing detection light receiving element 18, while it is possible to perform photographing fit positioning of the device easily, in any signal such as entering a signal in a predetermined region of the alignment light front eye part image in the eye part imaging apparatus before not shown equipped with stand the imaging system 3, and caused to advance from the standby position to the examinee's eye direction, the focusing as allowed to stop the advancement of the gantry when detecting endothelial reflected after detecting epithelial reflected detection light receiving element, it is possible to allow automatically detect shooting matching position.

【0023】 [0023]

【発明の効果】請求項1記載の本発明の角膜内皮撮影装置によれば、被検眼の角膜内皮細胞を撮影するに当り、 Effects of the Invention] According to the corneal endothelium photographing apparatus of the present invention according to claim 1, hit the shooting corneal endothelium of the eye,
装置本体に搭載した合焦検知用受光素子におけるスリット光の受光状態を制御して、角膜上皮反射光に比べ隔段に弱い角膜内皮反射光を該受光素子で確実に検出することができ、装置の撮影適合位置を手動のみならず自動的にも容易且つ確実に検出して撮影を行うことができる。 By controlling the light receiving state of the slit light in focus detection light receiving element mounted on the apparatus main body can be reliably detected by the light receiving element weak corneal endothelial reflected light 隔段 than in corneal epithelial reflected light device shooting matching position of can be performed manually not only automatically be easily and reliably detected and photographed.

【0024】請求項2記載の発明によれば、合焦検知用受光素子で被検眼の角膜反射光を検出して合焦を検知する場合、角膜内皮反射光を近接した上皮反射光から分離を良くして確実に検出させることができる。 According to the second aspect of the present invention, if in-focus detection light receiving element detects the cornea reflection light of the eye for detecting the focus, the isolated epithelial reflected light proximate the corneal endothelial reflected light it can be reliably detected well.

【0025】請求項3記載の発明によれば、合焦検知用受光素子で被検眼の角膜反射光を検出して合焦を検知する場合、暗くて検出しにくい内皮反射光を明るくして、 According to the invention of claim 3, wherein, if in-focus detection light receiving element detects the cornea reflection light of the eye for detecting the focus, to brighten the dark and difficult to detect endothelium reflected light,
上皮反射と内皮反射の強度差を少くし、角膜反射光を確実に検出させることができる。 The intensity difference of the epithelium reflection and endothelium reflection small comb, it is possible to reliably detect the corneal reflection light.

【0026】請求項4記載の発明によれば、合焦検知用受光素子で被検眼の角膜反射光を検出して合焦を検知する場合、暗くて検出しにくい内皮反射光を受光感度を高くした受光素子で受けるようにして上皮反射と内皮反射の検出信号差を少くし、角膜内皮反射光を確実に検出させることができる。 According to the fourth aspect of the present invention, a high light receiving sensitivity case, dark and difficult to detect endothelium reflected light to detect the focus by detecting the corneal reflection light of the eye in the focus detecting light receiving element small comb detection signal difference as received by the light receiving element epithelium reflection and endothelium reflection, the corneal endothelial reflected light can be reliably detected that.

【0027】請求項5記載の発明によれば、合焦検知用受光素子で被検眼の角膜反射光を検出して合焦を検知する場合、スリット状の角膜反射像の全体を受光素子で無駄なく受けることができ、合焦受光素子における角膜内皮反射光の検出能力を上げることができる。 According to the invention of claim 5, wherein, if in-focus detection light receiving element detects the cornea reflection light of the eye for detecting the focus, wasting the whole of the slit of the cornea reflection image at a light receiving element can be received without, it is possible to enhance the detection capability of the corneal endothelial reflected light at focusing the light receiving element.

【0028】請求項6記載の発明によれば、スリット照明光学系で、撮影用と別個に検出用のスリット状絞りを持つことにより、スリット照明の巾方向の寸法をその目的によって使い分け、角膜内皮反射光を精度良く検出して、広い視野で撮影することができる。 According to the sixth aspect of the present invention, a slit illumination optical system, by having a slit-shaped aperture for separately detecting and for photography, selectively using the width dimension of the slit illumination by the object, the corneal endothelium the reflected light is accurately detected, it can be taken in a wide field of view.

【図面の簡単な説明】 BRIEF DESCRIPTION OF THE DRAWINGS

【図1】本発明の実施例の光路図、 [1] optical path diagram of the embodiment of the present invention,

【図2】図1における合焦の原理を示す斜視図、 Figure 2 is a perspective view showing the principle of focusing in Figure 1,

【図3】受光素子前面のスリット状絞りの有無による上皮反射と内皮反射の分離状況を示す曲線図、 [Figure 3] curves illustrating separation conditions of the epithelium reflection and endothelium reflection by the presence or absence of the slit-shaped aperture of the light-receiving element front,

【図4】受光素子における上皮反射受光信号の立上りをとらえて受光素子をゲインUPしたときの受光信号の曲線図、 [4] curves of the light receiving signal when the gain UP the light receiving element captures the rise of epithelial reflected light signal in the light receiving element,

【図5】スリット照明光学系の検出用、撮影用の絞り変換時の受光素子の受光エリアと角膜反射光との関係を示す模式図、 [5] for the detection of the slit illumination optical system, schematically showing the relationship between the light receiving area and the cornea reflection light of the light receiving element at the time of stop conversion for photography,

【図6】撮影時の実際の角膜反射光図である。 FIG. 6 is a fact of the corneal reflection light view at the time of shooting.

【符号の説明】 DESCRIPTION OF SYMBOLS

1…眼球、 2…眼球面(角膜)、 3…撮影系、 4 1 ... eyeball, 2 ... eye surface (cornea), 3 ... imaging system, 4
…照明ランプ、7…検出用スリット絞り、 8…ストロボ放電管、 10…撮影用スリット絞り、11…赤外光反射・可視光透過ミラー、 12…照明光軸、 13…投影レンズ、14 1 , 14 2 , 14 3 …拡大撮影光軸、 15…対物レンズ、 16…赤外光透過・可視光反射ミラー、 17…スリット絞り、 18…合焦検知用受光素子、 20…拡大レンズ、 21…ミラー、 22…CCD受光面(受像面)、 ... lighting lamps, 7 ... throttle detection slit, 8 ... flash discharge tube, 10 ... photographic stop slit, 11 ... infrared reflecting and visible light-transparent mirror, 12 ... illumination optical axis, 13 ... projection lens, 14 1, 14 2, 14 3 ... enlarged photographing optical axis, 15 ... objective lens, 16 ... infrared light transmission and visible light reflecting mirrors, 17 ... slit diaphragm, 18 ... focus detection light receiving element, 20 ... magnifying lens, 21 ... mirror , 22 ... CCD light-receiving surface (image-receiving surface),
23…テレビカメラ。 23 ... TV camera.

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【手続補正書】 [Procedure amendment]

【提出日】平成5年10月8日 [Filing date] 1993 October 8

【手続補正1】 [Amendment 1]

【補正対象書類名】明細書 [Correction target document name] specification

【補正対象項目名】0003 [Correction target item name] 0003

【補正方法】変更 [Correction method] change

【補正内容】 [Correction contents]

【0003】 [0003]

【発明が解決しようとする課題】ところが、これらの従来の装置では、テレビカメラを付設した顕微鏡架台をジョイスティック等の操作部材を用いて手動で本体である上記架台を前後方向に移動せしめて角膜内皮の合焦を行っていたが、被検部をスリット照明してその角膜反射光を用いて合焦するに際し、上皮反射が強くて内皮反射が弱くその差が大きいため、内皮反射光検出が困難で角膜内皮の合焦がしにくいという問題があった。 [SUMMARY OF THE INVENTION However, in these prior art devices, the corneal endothelium manually moved the frame is the main body in the longitudinal direction by using the operation member such as a joystick microscope stand that attaching a television camera the While focusing has been performed, when focused by using the corneal reflection light by the slit illuminating the object part, due to the large the difference weaker endothelial reflected strong epithelial reflection, difficult endothelial reflected light detection in there is a problem that it is difficult scorched case of corneal endothelium. そのため、 for that reason,
被検部の角膜内皮細胞に合焦せしめるまで相当の手間と習熟を必要とした。 It required the skill and considerable time until allowed to focus on the corneal endothelial cells of the subject part.

Claims (6)

    【特許請求の範囲】 [The claims]
  1. 【請求項1】被検眼の眼球面をスリット照明する照明系と、眼球面を照射したスリット照明光に基づき被検部の拡大像を結像させるための拡大撮影光学系と、該拡大撮影光学系の結像面に角膜内皮像が合焦状態で結像するとき少くとも対物レンズを介してスリット光の角膜内皮反射光又は角膜上皮反射光を受光する位置に設定された合焦検知用受光素子と、合焦検知用受光素子におけるスリット光の受光状態を制御して角膜内皮反射光の検出能力を向上させるための受光状態制御手段と、上記装置本体を角膜内皮合焦位置に来るように被検眼方向に移動させる手段とからなることを特徴とする角膜内皮撮影装置。 1. A an illumination system of the eye surface of an eye to slit illumination, the enlarged image taking optical system for forming an enlarged image of the object part on the basis of the slit illumination light irradiating the ocular surface, the enlarged image taking optical at least the light receiving focus detection which is set in a position for receiving the corneal endothelial reflected light or cornea epithelium reflected light of the slit light via the objective lens when a cornea endothelium image on the imaging plane of the system is imaged in a focused state an element, a light receiving state control means for controlling the light receiving state of the slit light to improve the detection capability of the corneal endothelial reflected light at the focus detection light-receiving element, the device body to come to the corneal endothelium focusing position corneal endothelium photographing apparatus characterized by comprising a means for moving the eye direction.
  2. 【請求項2】合焦検知用受光素子における受光状態制御手段は、該合焦検知用受光素子の前方に配置されたスリット照明光による角膜反射像の長手方向に長いスリット状の絞りである請求項1記載の角膜内皮撮影装置。 Receiving state control means in 2. A focus detection light receiving element, claims a diaphragm longitudinally long slit-like image of corneal reflection by the slit illumination light is disposed in front of 該合 focus detection light receiving element corneal endothelium imaging device according to item 1, wherein.
  3. 【請求項3】合焦検知用受光素子における受光状態制御手段は、該合焦検知用受光素子による上皮反射光検出信号で、上記照明系のスリット照明光量を上げるようにした請求項1記載の角膜内皮撮影装置。 Receiving state control means in 3. focus detection light receiving element, epithelial reflected light detection signal by 該合 focus detection light receiving element, according to claim 1, wherein was set to raise the slit illumination light amount of the illumination system corneal endothelium photographing device.
  4. 【請求項4】合焦検知用受光素子における受光状態制御手段は、該合焦検知用受光素子による上皮反射光検出信号で、合焦検知用受光素子の受光感度を上げるようにした請求項1記載の角膜内皮撮影装置。 Receiving state control means in 4. focus detection light receiving element, epithelial reflected light detection signal by 該合 focus detection light receiving element, according to claim 1 which is to raise the light sensitivity of the focus detection light receiving element corneal endothelium imaging apparatus according.
  5. 【請求項5】合焦検知用受光素子における受光状態制御手段は、該合焦検知用受光素子の前方に配置されたスリット照明光による角膜反射像の長手方向を圧縮する光学系である請求項1記載の角膜内皮撮影装置。 Receiving state control means in 5. focus detection light receiving element Claim an optical system for compressing the longitudinal direction of the image of corneal reflection by the slit illumination light is disposed in front of 該合 focus detection light receiving element 1 corneal endothelium imaging apparatus according.
  6. 【請求項6】合焦検知用受光素子における受光状態制御手段は、上記スリット照明光学系において撮影用のスリット状絞りと別個に設けた該撮影用スリット状絞りより狭巾の検出用スリット状絞りである請求項1記載の角膜内皮撮影装置。 Receiving state control means in 6. focus detection light receiving element, said at slit illumination system diaphragm slit for imaging and separately the imaging slit-shaped aperture from Semahaba detection slit-shaped aperture provided corneal endothelium photographing apparatus according to claim 1, wherein it is.
JP5241986A 1993-09-02 1993-09-02 Cornea endothelium photographing device Pending JPH0767837A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5241986A JPH0767837A (en) 1993-09-02 1993-09-02 Cornea endothelium photographing device

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP5241986A JPH0767837A (en) 1993-09-02 1993-09-02 Cornea endothelium photographing device
US08/296,031 US5471261A (en) 1993-09-02 1994-08-25 Apparatus for obtaining images of cornea endothelium
EP19940113392 EP0641541B1 (en) 1993-09-02 1994-08-26 Apparatus for obtaining images of cornea endothelium
DE1994619089 DE69419089T2 (en) 1993-09-02 1994-08-26 Instrument for displaying images of the endothelium of the cornea
DE1994619089 DE69419089D1 (en) 1993-09-02 1994-08-26 Instrument for displaying images of the endothelium of the cornea

Publications (1)

Publication Number Publication Date
JPH0767837A true JPH0767837A (en) 1995-03-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP5241986A Pending JPH0767837A (en) 1993-09-02 1993-09-02 Cornea endothelium photographing device

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Country Link
JP (1) JPH0767837A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008505673A (en) * 2004-07-08 2008-02-28 コストルツィオーニ ストルメンチ オフタルミチ シー.エス.オー. エス.アール.エル. Reflection microscope for examination of corneal endothelium and method of operating the microscope
JP2017060809A (en) * 2016-11-18 2017-03-30 株式会社トプコン Ophthalmologic apparatus

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008505673A (en) * 2004-07-08 2008-02-28 コストルツィオーニ ストルメンチ オフタルミチ シー.エス.オー. エス.アール.エル. Reflection microscope for examination of corneal endothelium and method of operating the microscope
JP2017060809A (en) * 2016-11-18 2017-03-30 株式会社トプコン Ophthalmologic apparatus

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