JPH07505621A - 外科手術中における腫瘍組織の検出および探知法 - Google Patents

外科手術中における腫瘍組織の検出および探知法

Info

Publication number
JPH07505621A
JPH07505621A JP5516829A JP51682993A JPH07505621A JP H07505621 A JPH07505621 A JP H07505621A JP 5516829 A JP5516829 A JP 5516829A JP 51682993 A JP51682993 A JP 51682993A JP H07505621 A JPH07505621 A JP H07505621A
Authority
JP
Japan
Prior art keywords
group
peptide
formula
labeled
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5516829A
Other languages
English (en)
Japanese (ja)
Inventor
エンシング、ゲールト・ヤーコプ
パーネク、カーレル・ヤン
ドゥーデンス、バーレルト・ヤン
Original Assignee
マリンクロッド・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マリンクロッド・インコーポレイテッド filed Critical マリンクロッド・インコーポレイテッド
Publication of JPH07505621A publication Critical patent/JPH07505621A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP5516829A 1992-03-25 1993-03-24 外科手術中における腫瘍組織の検出および探知法 Pending JPH07505621A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP92200848.7 1992-03-25
EP92200848 1992-03-25
PCT/US1993/002772 WO1993018797A1 (fr) 1992-03-25 1993-03-24 Procede pour detecter et localiser de façon peroperatoire des tissus tumoraux

Publications (1)

Publication Number Publication Date
JPH07505621A true JPH07505621A (ja) 1995-06-22

Family

ID=8210503

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5516829A Pending JPH07505621A (ja) 1992-03-25 1993-03-24 外科手術中における腫瘍組織の検出および探知法

Country Status (5)

Country Link
EP (1) EP0636032A1 (fr)
JP (1) JPH07505621A (fr)
AU (1) AU3967593A (fr)
CA (1) CA2131315A1 (fr)
WO (1) WO1993018797A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2183421A1 (fr) * 1994-02-18 1995-08-24 John Mertens Composes peptidiques marques
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
AUPO066096A0 (en) * 1996-06-26 1996-07-18 Peptide Delivery Systems Pty Ltd Oral delivery of peptides
HUP0001316A3 (en) * 1997-02-03 2001-10-29 Mallinckrodt Inc Method for the detection and localization of malignant human tumours
EP1115429A1 (fr) * 1998-09-25 2001-07-18 Mallinckrodt Inc. Radioligand recepteur de la somatostatine, a absorption amelioree
US6331703B1 (en) 1999-03-12 2001-12-18 Ethicon Endo-Surgery, Inc. Guidance method for radiation detection
US6167297A (en) * 1999-05-05 2000-12-26 Benaron; David A. Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
US7259234B2 (en) 2003-05-15 2007-08-21 Trustees Of Tufts College Stable analogs of peptide and polypeptide therapeutics
WO2005018682A2 (fr) 2003-08-20 2005-03-03 The Regents Of The University Of California Analogues de somatostatine a activite inhibitrice de liberation d'hormone de croissance
US8318668B2 (en) 2005-09-08 2012-11-27 Trustees Of Tufts College Stabilized GLP-1 analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
EP0436005B1 (fr) * 1989-07-20 1995-03-29 Sandoz Ltd. Derives de polypeptide etiquetes

Also Published As

Publication number Publication date
CA2131315A1 (fr) 1993-09-30
AU3967593A (en) 1993-10-21
WO1993018797A1 (fr) 1993-09-30
EP0636032A1 (fr) 1995-02-01

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