JPH07258054A - Mouse wash liquid combined with tea extract - Google Patents

Abstract

PURPOSE:To obtain a mouse wash liquid combined with a tea extract, capable of preventing oxidation of tea leaf components and tubidity or precipitation, and having an excellent stabilizing activity, by adding a surfactant and an organic acid to a solution combined with a tea extract containing catechines extracted from the tea leaves as effective ingredients. CONSTITUTION:To a solution combined with a tea extract containing catechines extracted from tea as effective ingredients, an noionic surfactant such as a polyoxyethylene sorbitan fatty acid ester, etc., and citric acid or an organic acid such as vitamin C, etc., are added to adjust the solution at a weak acid of pH 4-6. This mouse wash solution combined with the tesa extract is stored under sealing in a bag container filled with nitrogen, having an aluminum foil which can seal a volume of liquid for about one time use, and having a hole for pouring out in one portion which can be open up as a slit like opening by cutting. It can be used for a long period of time under suitable conditions and is useful for preventing periodontal diseases and foul breath.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a mouthwash containing tea extract containing catechins extracted from tea leaves (hereinafter referred to as tea catechin) as an active ingredient.

[0002]

2. Description of the Related Art Halitosis is caused by physiological and pathological halitosis, and the latter includes systemic and local halitosis. About 80% of the cause of halitosis is this local halitosis, and it has been clarified by recent studies that the cause is periodontal disease derived from oral bacteria. As a known technique for preventing bad breath, research utilizing a chemical reaction by flavonoid which is a tea leaf extract has been used recently. It tries to react flavonoids with the contents of the stomach by swallowing, but the administration of such drinkable fungicides and antibiotics indiscriminately kills the bacteria resident in the oral cavity. However, there has been a problem that useful oral bacteria are also killed and, in addition, useful intestinal bacteria may be affected.

On the other hand, it has not been shown to prevent periodontal disease by suppressing the growth of periodontopathic bacteria in the oral cavity, thereby preventing halitosis. Therefore, the present inventor, in order to prevent the occurrence or recurrence of periodontal disease, and at the same time, because periodontal disease is the largest cause of halitosis, to prevent halitosis, the oral bacteria that causes it. In order to develop an effective method to suppress the growth of tea, we focus on the fact that the tea that we drink daily has antibacterial properties, and extract it from water or hot water extracts of tea or hydrophilic organic solvent extracts such as ethanol. Using the obtained catechins as active ingredients, we succeeded in obtaining mouthwashes such as anti-periodontal disease and breath freshening agents (JP-A-3-2).
18320).

[0004]

However, since catechins are polyphenols, they are easily oxidized and deteriorated, and it is difficult to sell them as they are.
In addition, catechins are bound to other contained substances to cause turbidity or precipitation, which is unstable, which causes a problem of causing discomfort to the user. Therefore, in the present invention, in view of the above problems, the tea extract-containing mouthwash derived from tea catechin can be used for a long period of time in a suitable state so as to prevent the oxidation of tea catechin, and to make it cloudy or precipitate. It is intended to be provided as a mouthwash containing a tea extract capable of preventing the occurrence of

[0005]

Means for Solving the Problems In the present invention, a surfactant and an organic acid are added to a tea extract formulation liquid containing tea catechin as an active ingredient to prevent precipitation of tea leaf components and formulate tea extract. We succeeded in stabilizing the mouthwash.

The tea extract-containing liquid containing tea catechin as an active ingredient is obtained by filtering, for example, a water or hot water extract of tea or a hydrophilic organic solvent extract such as ethanol with an ultrafiltration membrane or silicon earth. Can be obtained by removing the polymer compound. The ultrafiltration membrane is a filtration membrane that separates a high molecular compound having a molecular weight of about 10,000 or more by using a polyolefin-based, polysulfone-based, polyimide-based organic material membrane and an inorganic membrane made by surrounding various inorganic materials as a base material. Is desirable.

By adding the above-mentioned surfactant, the tea extract-containing solution exhibits solubilization, prevents the occurrence of turbidity or precipitation, and makes a stable and transparent solution. Examples of the surfactant include nonionic surfactants such as polyoxyethylene sorbitan fatty acid ester, polyoxyethylene hydrogenated castor oil, and polyglycerin fatty acid ester, anionic surfactant, cationic surfactant, or amphoteric surfactant. Although an activator can be used, a nonionic surfactant is preferable from the viewpoint of solubility and safety. Above all, HL
A B value of 10 to 18 is preferable from the viewpoint of hydrophilicity. The amount of the surfactant blended is preferably about 1 to 5 times or about 0.5 to 2.0% by weight of the catechins and fragrances to be added. If it is less than this range, the solubilization of the water-insoluble matter contained in the fragrance and tea components will be poor, and if it is more than this range, the bitterness of the surfactant will appear, which is not preferable.

By adding the above-mentioned organic acid, it is possible to prevent the oxidation of tea catechin and the like contained in the blended liquid by making the blended liquid of tea extract acidic. The acidity of the tea extract-containing mouthwash is preferably adjusted to a low acidity (PH4 to 6), particularly around PH5. When the acidity is stronger than PH4, the acidity is too strong and dangerous for human use. On the contrary, when the acidity is weaker than PH6, the antioxidant effect of tea catechin is impaired. As the organic acid, citric acid, tartaric acid, vitamin C, malic acid, succinic acid and the like can be used.

As a combination of the above-mentioned surfactant and the above-mentioned organic acid, from the viewpoint of prevention of precipitation, taste and price, polyoxyethylene sorbitan fatty acid ester and citric acid, polyoxyethylene sorbitan fatty acid ester and vitamin C. And are preferred.

Further, in the present invention, the tea extract compounding liquid is stabilized by sealing the tea extract compounding liquid in a storage container and further filling with nitrogen to prevent oxidation of tea catechin and the like in the compounding liquid. It was also successfully saved in.

Preferably, the storage container is a bag-shaped container having an oxygen-impermeable coating in which a liquid amount for a single use is sealed, and a spout capable of opening in a narrow mouth by being divided at one end thereof. If the tea extract blended liquid is hermetically stored using a container having, it is possible not only to more reliably prevent the oxidation of tea catechin during storage but also to use it by making it into a single-use disposable form. It is also possible to prevent the oxidation of tea catechin and the like. In addition, since it has a spout that can be divided and opened in a narrow mouth, the tea extract-containing liquid is easy to drink. This storage container is, for example, an oxygen-impermeable metal film or sheet, for example, a plastic film or sheet deposited on the inside of an aluminum film or sheet,
The laminated body can be formed into a bag shape by adhering and laminating it by a fixing means such as adhesion or pressure bonding.

[0012]

【Example】

[Method for extracting tea catechin] 1 kg of green tea at 60 ° C, 15 L
After extracting for 25 minutes with water at the temperature of 25 minutes, squeezing lightly and collecting the juice, and concentrating it to 2.2 times, this is applied with a polysulfone-based organic material ultrafiltration membrane (using HTU3520 manufactured by Nitto Denko) The polymer compound was removed by an ultrafiltration method to obtain a 5.2 L tea extract containing 77 g of catechins.

[Stabilization Method] Tween-20 (trade name: manufactured by ICI) as polyoxyethylene sorbitan fatty acid ester, citric acid and the like were added to the green tea extract obtained by the above method, for example as follows. When the tea extract-containing mouthrinse is mixed with and treated, the tea extract-containing mouthwash can be stabilized. Total tea extract 1.5%, ethanol 8%, glycerin
8%, Tween-20 1.5%, citric acid 1%, parapen
0.01%, water 79.99% The composition of the mouthwash can be changed depending on the taste, such as the concentration of tea catechin.

[Vessel for mouthwash containing tea extract] FIG. 1 (A)
(C) are containers 1, 10, 20 for preferably hermetically storing a tea extract compounded liquid containing catechins obtained from the above tea as an active ingredient and a surfactant and an organic acid.
Are shown respectively. Container 1 shown in FIG. 1 (A)
Is an aluminum film or sheet 2 on which a plastic film or sheet 3 is vapor-deposited and laminated, and this laminated body is formed into a bag shape having a shape like a triangular pyramid in appearance. Mouth opening 4
Is provided.

The container 10 shown in FIG. 1B is also the container 1 described above.
Similarly to the above, a laminated body in which a plastic film or sheet 12 is vapor-deposited on an aluminum film or sheet 11 is formed into a bag shape having a shape of a rectangular parallelepiped, and the upper portion is fixed over a suitable vertical width with one side leaving an appropriate width. However, a spout 13 similar to the spout 4 is provided near the upper end of the one side end that is not fixed. In addition, the container 20 shown in FIG. 1C also has a plastic film or sheet 22 on an aluminum film or sheet 21 like the container 1 described above.
The vapor-deposited laminated body is formed into a bag shape having a shape such that an upper protruding portion of an appropriate width is provided on one side upper end edge of the rectangular parallelepiped, and one side of the upper protruding portion similar to the spout 4 is formed. Outlet 2
3 is provided. In addition, these containers 1, 10, 2
It is desirable that 0 is in a single-use disposable form in order to prevent deterioration of the tea extract-containing liquid. Therefore, it is desirable that the capacity of the container is a liquid amount for one-time use, for example, about 10 ml.

[0016]

EFFECTS OF THE INVENTION According to the present invention, it is possible to prevent deterioration of the mouthwash containing tea extract, and to prevent turbidity or precipitation. Therefore, the mouthwash containing tea extract containing tea catechin as an active ingredient can be used in a suitable state for a long period of time.

[Brief description of drawings]

1 (A) to 1 (C) are cross-sectional views showing different examples of a tea extract-containing mouthwash liquid container.

[Explanation of symbols]

 1,10,20 Containers 2,11,21 Aluminum film or sheet 3,12,22 Plastic film or sheet 4,13,23 Spout

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Iwa Sakane, Goddess Sagara-cho, Haibara-gun, Shizuoka prefecture, 21 Goddess of Ito-en Central Research Institute (72) Toshio Kawasaki, Goddess, 21 Sagara-cho, Hara-gun, Shizuoka prefecture (72) Inventor Yasuo Sugawara 3-28-13, Shiroyamadai, Hashimoto-shi, Wakayama (72) Inventor Takashi Sasaoka 1-10-40-1014 Shimo-rokumanji-cho, Higashiosaka-shi, Osaka

Claims (4)

[Claims] 1. A mouthwash containing a tea extract, which is obtained by adding a surfactant and an organic acid to a tea extract containing a catechin obtained from tea as an active ingredient. 2. A tea extract-containing liquid containing catechins as an active ingredient, which is obtained by filtering a water or hot water extract or a hydrophilic organic solvent extract of tea with an ultrafiltration membrane or silicon earth, and a surfactant. Mouth rinsing solution containing tea extract, which is obtained by adding lactic acid and organic acid. 3. A tea extract-containing mouthrinse liquid obtained by sealing a storage container with a tea extract-containing liquid obtained by adding the surfactant according to claim 1 or 2 and an organic acid and filling it with nitrogen. 4. A bag-shaped container having an oxygen-impermeable coating in which a liquid amount for single-use use is sealed, the container having a spout capable of opening in a narrow mouth by being divided at one end thereof. A tea extract-containing mouthwash containing catechins obtained from tea as an active ingredient, and a tea extract-containing solution containing a surfactant and an organic acid, which is hermetically stored.