JPH07102209B2 - Laser device for blood collection - Google Patents

Laser device for blood collection

Info

Publication number
JPH07102209B2
JPH07102209B2 JP3106530A JP10653091A JPH07102209B2 JP H07102209 B2 JPH07102209 B2 JP H07102209B2 JP 3106530 A JP3106530 A JP 3106530A JP 10653091 A JP10653091 A JP 10653091A JP H07102209 B2 JPH07102209 B2 JP H07102209B2
Authority
JP
Japan
Prior art keywords
blood
laser beam
laser
laser device
finger
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP3106530A
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Japanese (ja)
Other versions
JPH04314428A (en
Inventor
アレキサンドロビッチ ゴルベフ ニコライ
ゲナリエヴィッチ ポルシュキン ヴァレリィ
ミハイロビッチ テン アンドレイ
ヤロスラボビッチ ニキルイ エルネスト
良夫 肥田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Futec Inc
Original Assignee
Futec Inc
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Filing date
Publication date
Application filed by Futec Inc filed Critical Futec Inc
Priority to JP3106530A priority Critical patent/JPH07102209B2/en
Publication of JPH04314428A publication Critical patent/JPH04314428A/en
Publication of JPH07102209B2 publication Critical patent/JPH07102209B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/14—Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
    • A61B5/1405—Devices for taking blood samples
    • A61B5/1411—Devices for taking blood samples by percutaneous method, e.g. by lancet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15134—Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids
    • A61B5/15136—Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids by use of radiation, e.g. laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Otolaryngology (AREA)
  • Electromagnetism (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Radiation-Therapy Devices (AREA)
  • Lasers (AREA)

Description

【発明の詳細な説明】Detailed Description of the Invention

【０００１】[0001]

【産業上の利用分野】この発明は皮膚表面から血液を採
取する際に用いる、採血用レーザ装置に関するものであ
る。 BACKGROUND OF THE INVENTION The present invention collects blood from the skin surface.
The present invention relates to a laser device for blood collection used when collecting blood.
It

【０００２】[0002]

【従来の技術】従来、血液を採取するにあたっては注射
器の注射針で腕や耳たぶの皮膚を突き刺し、その後注射
器で血液を吸い上げる方法を採っている。2. Description of the Related Art Conventionally, when collecting blood, a method has been adopted in which the skin of an arm or an ear lobe is pierced with an injection needle of a syringe and then blood is sucked up with the syringe.

【０００３】[0003]

【発明が解決しようとする課題】しかしながらそのよう
な方法では、直接注射針を皮膚に突き刺すので、衛生上
多大な注意を必要とする。特に最近では注射針に付着し
ていたウィルス等が原因となって、エイズやＢ型肝炎に
感染した事例も数多く報告されており、注射器、注射針
の保存、取扱いには格別の注意を要する。また注射針を
皮膚に突き刺すので激痛が伴い、しかも突き刺した状態
で血液を吸い上げるので、痛みがその間中続く。また注
射器を扱う者個々人の技倆差によってそのような採取作
業の巧拙があることも否めなかった。However, in such a method, since the injection needle is directly pierced into the skin, great care is required in hygiene. In particular, recently, many cases of AIDS and hepatitis B infection due to viruses attached to the injection needles have been reported, and special care must be taken when storing and handling syringes and needles. Also, because the injection needle pierces the skin, it causes severe pain, and since the blood is sucked up while the needle is pierced, the pain continues throughout. In addition, it cannot be denied that there is a skill in such collection work due to the skill difference of each person who handles the syringe.

【０００４】[0004]

【課題を解決するための手段】この発明は上述のような
問題点に鑑みてなされたものであって、皮膚に器物が全
く接触することなく血液を採取できる装置を提供して問
題の解決を図るものであり、具体的にはレーザビームを
採取対象地点にピンポイント照射する如く構成されたも
のである。 SUMMARY OF THE INVENTION The present invention has been made in view of the above-mentioned problems, and provides a device capable of collecting blood without contacting the skin with an object at all, thereby solving the problem. The laser beam
It is configured to irradiate the target point with pinpoint
Of.

【０００５】但し、レーザビームの皮膚への照射につい
ては安全性に留意しなければならなず、しかもその目的
からして血液の凝固を防止しなければならない。例えば
手術において使われるレーザメスに用いられている炭酸
ガスレーザは、取扱いを誤ると壊疽を引き起こす虞れが
あり、またその波長も約１０μｍであるため血液が凝固
してしまう。However, regarding the irradiation of the skin with the laser beam, attention must be paid to the safety, and for that purpose, coagulation of blood must be prevented. For example, the carbon dioxide gas laser used in the laser scalpel used in surgery may cause gangrene if handled improperly, and its wavelength is about 10 μm, so that blood coagulates.

【０００６】そこでこの発明では、血液の主成分である
ヘモグロビン及び水等の吸収係数を考慮し、波長を１．
５〜３．０μｍとし、さらに血液採取という目的とそれ
に伴う安全はとに鑑み、レーザパルス幅が１００〜３０
０μｓｅｃ．、レーザエネルギーがパルスあたり１〜
１．５Ｊのレーザビームを採取対象表面である皮膚に対
してピンポイント照射する如く構成されたことを特徴と
するものである。 Therefore, in the present invention, considering the absorption coefficients of hemoglobin and water, which are the main components of blood, the wavelength is set to 1.
The laser pulse width is 100 to 30 in view of the purpose of blood collection and the safety associated therewith.
0 μsec. , Laser energy is 1 ~ per pulse
A 1.5 J laser beam is applied to the skin, which is the surface to be sampled.
It is characterized by being configured to perform pinpoint irradiation
To do.

【０００７】レーサビームの照射径は、当然のことなが
ら血液を採取するのに必要最小限であることが要求され
る。この点に鑑みれば、皮膚表面における照射径が０．
５〜３ｍｍとなるように設定することが望ましい。As a matter of course, the irradiation diameter of the laser beam is required to be the minimum necessary for collecting blood. In view of this point, the irradiation diameter on the skin surface is 0.
It is desirable to set it to be 5 to 3 mm.

【０００８】[0008]

【作用】この発明に係る採血用レーザ装置によって具体
的に血液を採取する手順について説明すると、例えば指
先の腹の部分に向けて、上記各範囲内でレーザビームを
照射する。すると照射点に極めて微小な傷がつき、そこ
から血液が滲み出る。その後は例えば指の背と腹を押え
るなどして指に適当な圧力を加えて、ガラス板やガラス
容器などに血液の滴を垂らせばよい。従って、傷口が他
物に接触することは全くない。The procedure for specifically collecting blood with the blood sampling laser device according to the present invention will be described . For example, a laser beam is irradiated within the above range toward the belly part of the fingertip. Then, an extremely small scratch is made on the irradiation point, and blood oozes from there. After that, for example, by pressing the back and belly of the finger, a suitable pressure is applied to the finger, and a drop of blood may be dripped on the glass plate or the glass container. Therefore, the wound never touches other objects.

【０００９】而して照射するレーザビームは波長が１．
５〜３．０μｍであるから、血液は凝固することはな
い。即ち、レーザビームが血液に照射されると、その波
長によっては血液の諸成分が光エネルギーを吸収してそ
の相互作用によって血液が凝固してしまう。特に凝固に
あたってはヘモグロビンと水の吸収が大きな影響を与え
る。図２はヘモグロビンと水の波長に対する吸収係数を
グラフに表わしたものであるが、波長が１．５〜３．０
μｍの範囲のレーザビームは水の吸収係数は比較的よ
く、一方ヘモグロビンの吸収係数は低い。そのためこの
範囲のレーザビームを皮膚に照射した場合、皮膚表面組
織の水分にエネルギーの大半が吸収されて皮膚表面組織
に穴があけられる一方、透過したビームではもはや血液
中の成分との相互作用が弱くなっているので、血液が凝
固することはないのである。The laser beam thus irradiated has a wavelength of 1.
Since it is 5 to 3.0 μm, blood does not coagulate. That is , when the blood is irradiated with the laser beam, various components of the blood absorb light energy depending on the wavelength, and the blood coagulates due to the interaction. Especially, in coagulation, absorption of hemoglobin and water has a great influence. FIG. 2 is a graph showing the absorption coefficient with respect to the wavelengths of hemoglobin and water.
Laser beams in the μm range have a relatively good absorption coefficient for water, while hemoglobin has a low absorption coefficient. Therefore, when the skin is irradiated with a laser beam in this range, most of the energy is absorbed by the water of the skin surface tissue and a hole is made in the skin surface tissue, while the transmitted beam no longer interacts with components in blood. Since it is weak, the blood will not clot.

【００１０】しかもレーザビームを照射している時間が
１００〜３００μｓｅｃ．、と極く一瞬の間であるか
ら、痛みは殆ど感じられないものである。Moreover, the time during which the laser beam is applied is 100 to 300 μsec. Since it is only for a moment, the pain is hardly felt.

【００１１】[0011]

【実施例】以下、本発明の実施例について説明すると、
図１は実施例に係るレーザ装置及び当該レーザ装置を使
用して指先の腹にレーザビームを照射している様子を示
しており、１はその内部に固体レーザを有する共振器で
あり、２は該共振器１を内蔵した本体であって、電源並
びに制御装置は別体のコントローラ３に設けられてい
る。前記本体２におけるレーザビームの出力側にはレン
ズフード４が設けられ、このレンズフード４の内側に集
光レンズ５が設けられ、共振器１から出力されるレーザ
ビームはこの集光レンズ５によって集光される。本実施
例で用いた固体レーザ材料は、ＧＳＡＧ：Ｃｒ３＋Ｅｒ
３＋である。EXAMPLES Examples of the present invention will be described below.
FIG. 1 shows a laser device according to an embodiment and a laser device using the same.
Application shows that the laser beam is applied to the finger pad.
And it is, 1 is a resonator having a solid laser therein, 2 is a main body with a built-in the resonator 1, the power supply and control device is provided in the controller 3 separate. A lens hood 4 is provided on the output side of the laser beam in the main body 2, and a condenser lens 5 is provided inside the lens hood 4, and the laser beam output from the resonator 1 is collected by the condenser lens 5. Be illuminated. The solid-state laser material used in this example is GSAG: Cr 3+ Er.
3+ .

【００１２】本実施例にかかるレーザ装置は以上の構成
であり、例えば指先から血液の採取を行うには、適宜の
台６の上に、その腹の部分を集光レンズ５に向けて被採
血者の指７を置く。この場合、レーザ装置の集光レンズ
５から発振されるレーザビームの照射ターゲットを固定
するために、台６の上面に適宜の係止体８を設定してお
くと便利である。即ちこの係止体８は、丁度人の指先が
少し入り込むようにその内側が湾曲しており、その上縁
部外方近傍にレーザビームが集光するように台６の上面
に固定されている。このようにすれば、被採血者の指の
大きさが異なっていても、常にほぼ一定の位置、一定の
大きさで指先にレーザビームをピンポイント照射するこ
とができる。[0012] The laser device according to this embodiment is the above construction, for example, to carry out the collection of blood from the fingertip, onto the appropriate base 6, the blood toward the portion of the belly condenser lens 5 Person's finger 7 is placed. In this case, in order to fix the irradiation target of the laser beam oscillated from the condenser lens 5 of the laser device, it is convenient to set an appropriate locking body 8 on the upper surface of the table 6. That is, the inside of the locking body 8 is curved so that a person's fingertip may be slightly inserted therein, and the locking body 8 is fixed to the upper surface of the base 6 so that the laser beam is focused near the outside of the upper edge of the locking body 8. . By doing so, even if the size of the finger of the blood sampling subject is different, the laser beam can be always applied to the fingertip at the substantially constant position and the constant size.

【００１３】而してそのようにして被採血者の指７にレ
ーザビームを照射すると、当該照射地点には微小な傷が
でき、血液が滲み出てくる。その後図３に示したよう
に、指７の背と腹を押せばさらに血液が滲み出る。この
状態で図３に示したようにガラス板のような適宜の受け
体９の上に落下させれば、当該受け体９に被採血者の血
液が採取できる。このようなプロセスから明らかなよう
に、被採血者の指７の傷口は他物と全く接触することは
なく、極めて衛生的である。またレーザビ−ムの照射時
間が１００〜３００μｓｅｃ．と極く一瞬であるから、
痛みも殆どない。またレーザビームの照射そのものは至
極単純な作業であるから、作業者の技倆に左右されるこ
とはなく、誰が行なっても均一な採血を実施することが
可能となっている。Thus, when the finger 7 of the blood sampler is irradiated with the laser beam in this manner, a minute scratch is formed at the irradiation point, and blood oozes out. After that, as shown in FIG. 3, when the back and belly of the finger 7 are pressed, blood further exudes. In this state, if it is dropped onto an appropriate receiving body 9 such as a glass plate as shown in FIG. 3, the blood of the blood collecting person can be collected in the receiving body 9. As is clear from such a process, the wound of the finger 7 of the blood sampling subject does not come into contact with anything else, and is extremely hygienic. The irradiation time of the laser beam is 100 to 300 μsec. Because it is a very instant,
Almost no pain. Also, since the irradiation of the laser beam itself is an extremely simple operation, it is not affected by the skill of the operator, and uniform blood collection can be performed by anyone.
It is possible .

【００１４】なお図４に示したように、レーザビームの
照射後指７の背と腹を押せば血液が滴状になって滲み出
るので、この状態のままスポイト等の適当な液体吸引器
で吸い取ってもよい。この場合にも傷口は血液を介して
間接的に該液体吸引器と接触しているだけである。従っ
て、従来の注射器による採血方法に比べて衛生的であ
る。As shown in FIG. 4, when the back and abdomen of the finger 7 are pressed after the laser beam is irradiated, the blood becomes droplets and oozes out. Therefore, in this state, suck it with an appropriate liquid suction device such as a dropper. May be. Also in this case, the wound only indirectly contacts the liquid suction device via blood. Therefore, it is more hygienic than the conventional blood sampling method using a syringe.

【００１５】[0015]

【発明の効果】この発明にかかる採血用レーザ装置を用
いれば、血液採取の過程で、傷口が他物と全く接触する
ことなく血液を採取することができ、極めて衛生的であ
る。しかも痛みが殆ど伴わない。また採血する者の個人
の技倆差に左右されずに均一的に血液採取を行なうこと
ができる。The laser device for blood collection according to the present invention is used.
If so , blood can be collected without any contact between the wound and other objects during the blood collection process, which is extremely hygienic. Moreover, there is almost no pain. Further, it is possible to collect blood uniformly without being influenced by the skill difference of the person who collects blood.

【図面の簡単な説明】[Brief description of drawings]

【図１】この発明の実施例を用いてレーザビームを被採
血者の指に照射している様子を示す説明図である。FIG. 1 is an explanatory view showing how a finger of a blood sampling subject is irradiated with a laser beam using an embodiment of the present invention.

【図２】血液中のヘモグロビン及び水の光波長に対する
吸収特性を表わしたグラフである。FIG. 2 is a graph showing absorption characteristics with respect to light wavelengths of hemoglobin and water in blood.

【図３】実施例を用いてピンポイント照射した後、指の
背と腹に圧力を加えて受け体に血液を垂らしている様子
を示す斜視図である。FIG. 3 is a perspective view showing a state in which pressure is applied to the back and abdomen of a finger and blood is dripped on a receiver after pinpoint irradiation is performed using an example .

【図４】実施例を用いてピンポイント照射した後、指の
背と腹に圧力を加えて血液を滲み出させている様子を示
す斜視図である。FIG. 4 is a perspective view showing a state in which pressure is applied to the back and abdomen of a finger to exude blood after pinpoint irradiation using the example .

【符号の説明】[Explanation of symbols]

１ 共振器 ２ 本体 ３ コントローラ ４ レンズフード ５ 集光レンズ ６ 台 ７ 指 ８ 係止体 ９ 受け体 1 Resonator 2 Main body 3 Controller 4 Lens hood 5 Condensing lens 6 units 7 Finger 8 Locking body 9 Receiving body

フロントページの続き (72)発明者 アンドレイ ミハイロビッチ テン レスコバ 21−28，モスコウ 127543 ソ ビエト社会主義連邦共和国 (72)発明者 エルネスト ヤロスラボビッチ ニキルイ クルスコイ ４−３−153，モスコウ 117311 ソビエト社会主義連邦共和国 (72)発明者 肥田 良夫 東京都世田谷区南烏山四丁目21番３号 株 式会社ヒューテック内Front page continuation (72) Inventor Andrei Mikhailovich Ten Rescova 21-28, Moskov 127543 Soviet Socialist Federal Republic (72) Inventor Ernesto Yaroslavovich Nikirui Kurskoy 4-3-153, Moskov 117311 Soviet Socialist Federal Republic (72) Inventor Yoshio Hida 4-21-3 Minamikarasuyama, Setagaya-ku, Tokyo Inside Hutech Co., Ltd.

Claims (1)

【特許請求の範囲】[Claims] 【請求項１】 血液採取に用いるレーザ装置であって、
採取対象表面に対して、波長が１．５〜３．０μｍ、レ
ーザパルス幅が１００〜３００μｓｅｃ．、レーザエネ
ルギーが１〜１．５Ｊ／パルスのレーザビームをピンポ
イント照射する如く構成されたことを特徴とする、採血
用レーザ装置。 1. A laser device for collecting blood, comprising:
With respect to the surface to be sampled , the wavelength is 1.5 to 3.0 μm and the laser pulse width is 100 to 300 μsec. , The laser energy is ping-pong a laser beam of 1~1.5J / pulse
Blood collection, characterized by being configured to irradiate
Laser device.
JP3106530A 1991-04-12 1991-04-12 Laser device for blood collection Expired - Lifetime JPH07102209B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3106530A JPH07102209B2 (en) 1991-04-12 1991-04-12 Laser device for blood collection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3106530A JPH07102209B2 (en) 1991-04-12 1991-04-12 Laser device for blood collection

Publications (2)

Publication Number Publication Date
JPH04314428A JPH04314428A (en) 1992-11-05
JPH07102209B2 true JPH07102209B2 (en) 1995-11-08

Family

ID=14435949

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3106530A Expired - Lifetime JPH07102209B2 (en) 1991-04-12 1991-04-12 Laser device for blood collection

Country Status (1)

Country Link
JP (1) JPH07102209B2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6315772B1 (en) 1993-09-24 2001-11-13 Transmedica International, Inc. Laser assisted pharmaceutical delivery and fluid removal
US5643252A (en) * 1992-10-28 1997-07-01 Venisect, Inc. Laser perforator
US5993439A (en) * 1994-08-29 1999-11-30 Cell Robotics, Inc. Lens shield for laser skin perforation
WO1998004201A1 (en) * 1996-07-26 1998-02-05 Venisect, Inc. Laser with matte crystal element and container unit
US6027496A (en) * 1997-03-25 2000-02-22 Abbott Laboratories Removal of stratum corneum by means of light
US6245386B1 (en) 2000-04-26 2001-06-12 Callaway Golf Company Method and system for finishing a golf ball
CA2627603A1 (en) 2006-03-22 2007-09-27 Matsushita Electric Industrial Co., Ltd. Biosensor and apparatus for measuring concentration of components
TW200911205A (en) 2007-04-29 2009-03-16 Arkray Inc Analyzing system
US20100292608A1 (en) 2007-04-29 2010-11-18 Arkray, Inc. Analysis instrument
WO2008136474A1 (en) 2007-04-29 2008-11-13 Arkray, Inc. Analysis device
WO2009008267A1 (en) * 2007-07-11 2009-01-15 Konica Minolta Opto, Inc. Bodily fluid collection device and bodily fluid collection method
JP5168280B2 (en) * 2007-07-17 2013-03-21 コニカミノルタアドバンストレイヤー株式会社 Body fluid collecting auxiliary member and body fluid collecting apparatus

Also Published As

Publication number Publication date
JPH04314428A (en) 1992-11-05

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