JPH0646990B2 - Endometrial embryo transfer needle - Google Patents

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an embryo transfer needle used for in vitro fertilization-embryo transfer, in which an early embryo obtained by in vitro fertilization is transferred into the uterine cavity.

[0002]

2. Description of the Related Art In vitro fertilization for transplanting an early embryo obtained by in vitro fertilization into the uterine cavity for infertility patients.
Embryo transfer is known.

FIG. 4 shows a front longitudinal section of the uterus and ovaries.
In the normal case, sperm enter from the vagina 27, pass through the fallopian canal 25, and within the fallopian tube 24, fertilize with an egg generated from the ovary 23 to become an early embryo. This early embryo moves from the fallopian tube 24 to the uterus 20 while repeating cleavage. The embryo that has moved to the uterus 20 implants on the endometrium 21 and grows into a fetus.

[0004] In vitro fertilization-embryo transfer, when the above-mentioned normal process is not carried out for some reason, instead of normal fertilization, an egg and a sperm are fertilized in vitro to form an early embryo. It is to be transplanted into the uterine cavity.

FIG. 5 shows conventional embryo transfer. As shown in FIG. 5, in the conventional embryo transfer, the early embryo is transferred to the uterine cavity 22 by the injector 10 having the transfer needle 1 attached thereto. The vagina 27 is opened by the speculum 11 so that the implantation needle 1 can be easily inserted into the uterine cavity 22.

[0006]

In the conventional embryo transfer shown in FIG. 5, only the early embryo is transferred into the uterine cavity 22,
Whether or not the transplanted early embryo is implanted in a predetermined part of the endometrium 21 is influenced by the condition of the early embryo and the condition of the endometrium 21. In this conventional embryo transfer, there is a 10-20% probability that the early embryo transferred into the uterine cavity 22 will be implanted in the endometrium 21.
That was not a very high probability.

[0007]

The needle for endometrial embryo transfer according to the present invention transfers an early embryo fertilized in vitro into the uterine cavity in order to increase the probability of embryo implantation in conventional embryo transfer. In in vitro fertilization-embryo transfer, an embryo to be transferred is directly transferred to a predetermined site on the endometrium to be implanted.

Therefore, the endometrial embryo transfer needle according to the present invention comprises an elastic inner needle having a curved front end portion and a rear end having a socket that can be connected to an injector, and the outer needle of the inner needle. A tubular outer needle having an inner diameter substantially equal to the diameter and accommodating the inner needle is provided, and when the outer needle moves in the retracting direction, the tip portion of the inner needle is It is stored inside, and when the inner needle moves in the forward direction, the curved distal end portion of the inner needle is configured to project from the outer needle.

[0009]

EXAMPLE FIG. 1 is a diagram showing an example of embryo transfer using the endometrial embryo transfer needle according to the present invention. In FIG. 1, the uterus 20 is shown in a lateral longitudinal section.

Inserting the transplant needle 1 into the uterine cavity 22 through the vagina 27 opened by the colposcope 11 is similar to the conventional embryo transfer method. The insertion position of the transplantation needle 1 is confirmed by a CT scanner or the like. Then, the tip portion 3 of the inner needle 2 of the transplantation needle 1 is inserted into a predetermined part of the endometrium 21. Thereafter, the early embryo is injected from the injector 10 into the endometrium 21 and is implanted in the endometrium 21.

A transplantation needle 1 used for this endometrial embryo transfer
Is composed of an inner needle 2 made of ethylene tetrafluoride or the like and excellent in elasticity and slidability, and a substantially linear solid outer needle 5 made of polyethylene or the like. The inner needle 2 has a tip portion 3
Is curved in a predetermined shape such as an arc or an elliptical arc,
At the rear end is formed a socket 4 which can be connected to the injector 10. Further, the distal end of the inner needle 2 is formed obliquely so as not to be excessively damaged when entering the uterine tissue. Further, the outer needle 5 has a through hole formed therein, through which the inner needle 2 can be inserted, a tip end 6 thereof is rounded, and a rear end thereof is formed with a base portion 7 for facilitating insertion operation.

FIG. 2 shows an implanting needle 1 according to the invention.
(A) shows the state in which the inner needle 2 is advanced, that is, the tip portion 3 is projected from the tip 6 of the outer needle 5. Further, (B) shows the state in which the inner needle 2 is retracted, that is, the tip portion 3 is stored inside the outer needle 5. When inserting the implanting needle 1 into the uterine cavity, the state shown in FIG. Although the tip portion 3 of the inner needle 2 is curved, since it has elasticity, it deforms when the tip portion 3 is stored in the outer needle 5. When the embryo is transplanted into the endometrium, the tip portion 3 of the inner needle 2 is projected from the outer needle 5 as shown in (A). The tip portion 3 has an original curved shape due to elasticity. The tip portion 3 of the inner needle 2
When projecting, the inner needle 2 may be projected by pressing the base portion 7 of the outer needle 5.

FIG. 3 shows a modification of the implantation needle 1.
(A) shows that the curvature of the tip portion 3 of the inner needle 2 is larger than that shown in FIG. Further, (B) shows the tip portion 3 of the inner needle 2 in a substantially S shape. The shape of the tip portion 3 of the inner needle 2 is the shape of the endometrium of the patient to whom the embryo transfer is applied,
An optimal shape may be used depending on the state.

In these transplantation needles, if the outer needle is made of polyethylene or the like having plasticity, the transplantation needle can be curved in an arch according to the shape of the uterine cavity or the like during embryo transfer. It can be done easily.

[0015]

INDUSTRIAL APPLICABILITY According to the endometrial endometrial embryo transfer needle of the present invention, since the early embryo to be transplanted is located at a predetermined site of the endometrium, the probability that the early embryo will be implanted in the endometrium is high. Very high.

[Brief description of drawings]

FIG. 1 is a side elevational cross-sectional view of a uterus for explaining an example of use of a needle for endometrial embryo transfer according to the present invention.

FIG. 2 (A) is a view showing a state in which the inner needle of the implantation needle according to the present invention is projected. (B) It is a figure which shows the state which stored the inner needle of the implantation needle by this invention.

FIG. 3 (A) is a view showing a first modification of the implantation needle according to the present invention. (B) It is a figure which shows the 2nd modification of the implantation needle by this invention.

FIG. 4 is a front longitudinal sectional view in which a part of the uterus is omitted.

FIG. 5 is a lateral longitudinal sectional view of a uterus for explaining an example of use of a conventional needle for embryo transfer.

[Explanation of symbols]

 1 Transplantation needle 2 Inner needle 3 Tip part 6 Outer needle 20 Uterus 21 Endometrium 22 Uterine cavity

Claims (1)

[Claims] 1. An elastic inner needle having a curved distal end portion and a socket at the rear end that can be connected to an injector, and an inner needle having an inner diameter substantially equal to the outer diameter of the inner needle and storing the inner needle. A tubular outer needle is provided, and when the inner needle moves in the backward direction, the tip portion of the inner needle is stored inside the outer needle, and when the inner needle moves in the forward direction. A needle for endometrial embryo transfer, wherein the curved tip portion of the inner needle projects from the outer needle.