JPH0638834B2 - Infusion container - Google Patents

Description

TECHNICAL FIELD The present invention relates to an infusion container used in the medical field, and in particular, a kit capable of dissolving a powdered drug in a solution or a diluent by a simple operation immediately before use. Regarding the product.

[Prior Art] A kit product in which a drug and a medical device are combined is used for the purpose of reducing the burden at the time of preparation of medication at a medical institution, preventing bacterial contamination and foreign material contamination, and the like.

The infusion solution used for drip injection is prepared by dissolving the powdered drug in a container such as a vial in a diluting solution such as sugar solution or physiological saline at the time of use. The simplicity of is desired.

A conventional infusion container as a kit product generally holds a drug container whose mouth is sealed with a pierceable stopper in a holding container,
This is connected to a flexible liquid container through an appropriate communication means. For example, as the communication means, a puncture needle is attached to the vial side and a breaking member is attached to the flexible liquid container side to make a puncture. A needle that pierces the rubber stopper of the drug container and then bends the breaking member by hand to connect both containers (Special Table Sho 61
No. 501,129), or a double-ended needle is used as a communication means, and both the drug container and the liquid container are pierced to communicate the two containers (JP-A-2-
1277).

[Problems to be Solved by the Invention] However, in the above-mentioned conventional example using the breaking member, it takes time to bend the breaking member, and if the opening by bending is not sufficient, the amount of liquid passing is small and the time required for dissolution is low. This is not preferable because it has the required drawbacks, and the fragments of the breaking member may fall off and enter the infusion solution. Further, in the conventional example using a double-ended needle, one of the double-ended needles pierces the stopper of the drug container first, and then the specially designed braking means for controlling the communication sequence so as to pierce the closing membrane of the flexible liquid container. The operation of such a braking means cannot be intuitively seen from the outside, and therefore the operation may be interrupted in an emergency.

The present invention has been made to solve the above-mentioned problems of the prior art, and can securely seal the liquid container before use, and at the time of use, the drug container and the flexible liquid container can be intuitively and easily operated. It is an object of the present invention to provide an infusion container capable of reliably communicating with and.

[Means for Solving the Problem] An infusion solution container of the present invention includes a holding member for movably holding an agent container whose mouth is sealed by a pierceable stopper in an axial direction, and a flexible liquid container. The communication means, which comprises a communication means for communicating the inside of the drug container and the inside of the flexible liquid container, the communication means, a communication pipe having an enlarged diameter portion with an expanded inner diameter in an axially intermediate portion,
A frictional stopper member for closing the opening of the communication tube on the drug container side, and a cap-like movement which is externally inserted from the drug container side of the communication tube and has a puncture needle axially protruding from the top surface toward the stopper of the drug container. It is composed of members. Then, the cap-shaped moving member is in a state in which the friction plug member located on the drug container side from the expanded diameter portion of the communication tube abuts on the tail end of the puncture needle and is prevented from moving to the flexible liquid container side. , The first position where the puncture needle can pierce the mouth stopper of the drug container that moves to the flexible liquid container side, and the mouth of the pierced drug container is on the top surface of the cap-shaped moving member. By contacting and further moving to the side of the flexible liquid container, the tail end of the puncture needle pushes the friction plug member so that the second position where the friction plug member is dropped into the expanded diameter portion of the communicating tube can be taken. Has become.

The friction plug member means a plug member such as a rubber plug that utilizes frictional resistance.

The tail end of the puncture needle is preferably formed in a flange shape having a diameter substantially equal to the inner diameter of the communication tube, and the friction plug member is pushed by this flange portion.

The drug container and its holding member may be separate from the liquid container and the communication means, and a cap may be placed over the communication means to form separate kit products.

[Operation] In the infusion solution container according to the present invention having the above-described configuration, the friction stopper member is located closer to the medicine container side than the expanded diameter portion of the communication tube before use, and the inside of the communication tube and the flexible liquid container communicated therewith. The friction plug member is in contact with the tail end of the puncture needle to prevent the cap-shaped moving member from moving toward the flexible liquid container.

Therefore, when the drug container held by the holding member is moved to the flexible liquid container side, the puncture needle is first pierced by the stopper at the mouth of the drug container.

When it is further moved and the mouth of the drug container comes into contact with the top surface of the cap-shaped moving member, the pushing force directly reaches the friction stopper member via the puncture needle inside the cap-shaped moving member. The friction plug member begins to move to the flexible liquid container side, and is finally dropped into the expanded diameter portion of the communication pipe.

In this state, the friction plug member is free to move in the axial direction, so that the tail end of the puncture needle is opened and the inside of the drug container and the inside of the flexible liquid container are communicated with each other.

[Examples] Next, the infusion solution container of the present invention will be described based on the examples shown in the accompanying drawings.

FIG. 1 is a cross-sectional view showing an entire infusion container according to an embodiment of the present invention, 10 is a flexible liquid container for containing a dissolving liquid or a diluting liquid (hereinafter referred to as a dissolving liquid), and 20 is a drug container. A holding container holding the vial 30 and a connecting portion 40 connecting them.

The liquid container 10 is a transparent flexible bag body made of a soft resin such as polyvinyl chloride resin, polyolefin resin, ethylene-vinyl acetate copolymer, and the like. The upper end is fused to the lower end of the connecting portion 40 and communicates with the inside of the connecting portion 40.

FIG. 2 is a cross-sectional view showing the state of the holding container 20 and the connecting portion 40 before use, that is, the state during transportation or storage.

The holding container 20 includes an outer cylinder 24 and an inner cylinder 26.
The liquid container side end of 4 is screwed into the base of the connecting portion 40,
An inner cylinder 26 is fitted to the other end so as to be able to move out. Outer cylinder 24
The collar 25 at the end of is used to put a finger when pushing the inner cylinder 26. Two ridges 27, 28 are provided around the inner cylinder 26.
Is formed, and the protrusions 27 and 28 are fitted into the circumferential groove 29 formed on the inner surface of the outer cylinder 24, whereby the inner cylinder 2 is formed.
6 can be fixed in two positions. Inner cylinder 2
The outer end of 6 is closed by a screw lid 32, and the vial 30 is inserted from here. At the position of the inner end of the inner cylinder 26, a vial fixing rubber ring 34 is inserted in contact with the inner surface of the outer cylinder 24. The rubber ring 34 fixes the vial 30 and maintains airtightness, and Two
6 prevents rattling when moving. Reference numeral 36 denotes a suspender, which is fixed to the screw lid 32 at a position of 36a, and its end portion 36b is in contact with the end portion of the outer cylinder 24 so that the inner cylinder 26 does not move when not in use. At this time, as shown in FIGS. 3 and 4, the slits 37a, 37b can be opened and can be suspended at an appropriate place by a hook (not shown) at the portion 36b.

On the other hand, the connecting portion 40 includes a communication pipe 42 connected to the upper end opening of the flexible liquid container 10, a rubber stopper 44 as a friction stopper member for closing the medicine container side opening of the communication pipe 42, and a medicine of the communication pipe. Cap-shaped moving member 46 that is externally inserted from the container-side opening
It is formed by. The communication pipe 42 has an enlarged diameter portion 42a having an enlarged inner diameter at an axially intermediate portion, and the rubber plug 44 has an enlarged diameter portion 4a.
The communication pipe 42 is located outside of 2a and seals the communication pipe 42, and the cap-shaped moving member 46 further covers the end portion of the communication pipe 42.
The cap-shaped moving member 46 is integrally provided with a puncture needle 48 that axially penetrates the top surface 46a toward the stopper of the vial mouth, and the tail end thereof has a flange shape having substantially the same diameter as the rubber stopper 44. It comes into contact with the top surface of the rubber plug 44. Also,
Protrusions 42b and 42c are provided on the outer circumference of the connecting pipe 42, and engage with the circumferential grooves 46b and 46c formed on the inner surface of the cap-shaped moving member 46 so that the cap-shaped moving member 46 is at two-stage positions. It is supposed to be fixed.

Next, the operation during use will be described with reference to FIGS. 2, 3, and 4.

First, in the first position of the cap-shaped moving member 46, that is, in the state where the rubber plug 44 is outside the enlarged diameter portion 42a of the communication tube 42 and seals the communication tube 42, the tail end of the puncture needle 48 is made of rubber. Since it is in contact with the stopper 44, the movement of the cap-shaped moving member 46 to the liquid container 10 side is prevented.
In this state, the suspending tool 36 is removed, and when the finger of the collar 25 of the outer cylinder 24 is put in and the portion of the screw lid 32 is pushed in, the mouth portion 31 of the vial 30 is formed of a rubber film at the center, so that the puncture needle is used. Four
The tip blade of No. 8 penetrates this to reach the state of FIG. In this state, since the mouth portion 31 of the vial 30 is in contact with the top surface 46a of the cap-shaped moving member 46, when the vial 30 is further pushed, this action force is directly exerted on the rubber stopper 44 via the tail end of the puncture needle 48. And the rubber plug 44 overcomes the frictional force between the rubber plug 44 and the connecting pipe 42, and the rubber plug 44 moves to the expanded diameter portion 42a of the communicating pipe 4.
Will be dropped into.

At the second position of the cap-shaped moving member 46, the rubber stopper 44 is free in the expanded diameter portion 42a, so that a gap is created around the expanded portion 42a, and at this stage, the inside of the vial 30 and the liquid container 10 are separated from each other. It will be communicated.

In this state, by pressing or bending the flexible liquid container 10, the dissolution liquid in the liquid container 10 is sent into or returned from the vial 30 to obtain the vial 30.
The powdered drug in can be dissolved. After dissolution, the tube is attached to the outlet 12 of the liquid container 10 and used as an infusion solution.

FIG. 5 is a sectional view showing another embodiment of the holding container 20 and the connecting portion 40, which is almost the same as the above embodiment except that the shape of the cap-shaped moving member 50 is different. Therefore, the same members are given the same reference numerals and the description thereof is omitted.

The cap-shaped moving member 50 of this embodiment has a shape in which the periphery of the flange portion 52 at the tail end of the puncture needle 48 is in contact with the inner surface of the communication tube 42 and rises to be connected to the top surface 46a.
The cap-shaped moving member 50 facilitates molding and can completely prevent liquid leakage from the communication pipe 42 after dropping the rubber plug 44.

In addition, in the above embodiment, the end portion of the holding container 20 is attached to the screw lid 32.
Although the screw lid 32 and the inner cylinder 26 may be integrally formed, the vial 30 may be inserted from the inside. Further, the holding member of the medicine container is the holding container 20.
It is not necessary to form it as a container body that wraps the entire drug container as described above, and any structure that can hold the drug container movably in the axial direction may be used.

[Effects of the Invention] As described above, the infusion container of the present invention has a piercing sequence based on the balance between the frictional resistance of the friction plug member and human power, without using a complicated communicating means for controlling the piercing sequence. Since the control is performed, the user can reliably connect the medicine container and the flexible liquid container by simply pushing the medicine container into the medicine container. Further, since the friction plug member is structured to be dropped into the expanded diameter portion of the communicating tube, unlike the case of being pierced by the puncture needle, the closing part on the liquid container side when not in use can be formed robustly and pierced. There is also no fear that the rubber dust generated at times will be mixed into the infusion solution.

[Brief description of drawings]

FIG. 1 is a sectional view showing an entire embodiment of the infusion container according to the present invention, FIG. 2 is a partial sectional view of the same embodiment when it is not used, and FIGS. 3 and 4 show the use of the same embodiment. FIG. 5 is a partial sectional view showing a mode of time, and FIG. 5 is a partial sectional view showing another embodiment of the present invention. DESCRIPTION OF SYMBOLS 10 ... Flexible liquid container 20 ... Holding container (holding member) 30 ... Drug container (vial) 31 ... Mouth part of drug container (vial) 40 ... Communication part 42 ... Communication pipe 42a ... Expanding part 44 of communication pipe 44 ... Friction plug member (rubber plug) 46 ... Cap-shaped moving member 46a ... Top surface of cap-shaped moving member 48 ... Puncture needle

Claims (1)

[Claims] 1. A holding member for holding a drug container whose mouth is sealed by a pierceable plug so as to be movable in the axial direction, a flexible liquid container, and the inside of the drug container and the flexible liquid container. An infusion container comprising a communication means for communicating the inside, wherein the communication means has a communication pipe having an enlarged diameter portion with an expanded inner diameter in an axial middle portion, and a friction plug member for sealing the medicine container side opening of the communication pipe. And a cap-shaped moving member that is externally inserted from the drug container side of the communication tube and has a puncture needle that axially protrudes from the top surface toward the stopper of the drug container, wherein the cap-shaped moving member is the communication tube. In the state in which the friction plug member located closer to the drug container than the expanded diameter portion of the needle abuts the tail end of the puncture needle and is prevented from moving toward the flexible liquid container, the puncture needle is The first position where the mouth stopper of the drug container moving to the container side can be pierced, and When the mouth of the drug container comes into contact with the top surface of the cap-shaped moving member and further moves toward the flexible liquid container, the tail end of the puncture needle pushes the friction plug member to connect the friction plug member to the communicating pipe. An infusion container characterized in that it can take a second position where it is dropped into the expanded diameter part of the.