JPH06165649A - Spongy konjaku composition - Google Patents

Abstract

PURPOSE:To provide a spongy konjaku composition containing specific compound(s), useful as a cleansing material not injuring the skin, keeping away from sundry germs and prevented from their proliferation because of having antifungal/antibacterial effect, thus usable in a clean state at all times. CONSTITUTION:The composition, a porous product obtained by freezing, thawing and then drying konjaku jelly, incorporated with (A) 0.05-3 pts.wt. of a compound of formula I [R is H or KNCONH(CH2)CH3; R2 is thiazolyl or NHCOOCH3 ] (e.g. 2-carbomethoxyaminobenzimidazole) and/or 0.1-5 pts.wt. of a compound of formula II (M is monovalent or divalent metal atom; (n is 1 or 2) @9146/28}e.g. bis(2-pyridylthio-1-oxido)zinc]. This composition can be obtained, for example, by incorporating devil's tongue root powder with the compound(s) of the formula I and/or formula II in the form of powder or dispersion followed by addition of a coagulating agent such as water or calcium hydroxide and then molding the resultant pasty kneaded product which is then frozen, thawed and dried, successively.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a sponge-like konjac composition having antibacterial and antifungal effects.

[0002]

2. Description of the Related Art Sponge-shaped konjac is a paste made by adding water or warm water to konjac flour, which is obtained by drying a thin slice of konjac potato and milling it into fine powder, and adding a coagulant such as calcium hydroxide to it. It is obtained by coagulating into plate-like konjac, then once frozen to separate water and konjac components, returned to normal temperature and thawed. The sponge-like konjac thus obtained has a softer feel than polyurethane, synthetic rubber, or a chimpanzee, and thus has been conventionally used as a cleaning tool that does not damage the skin.

[0003]

However, the above-mentioned spongy konjac is often stored in a water-containing state after use, and as time goes by, mold develops on its surface, or the water contained contains bacteria. There was a problem that it would rot and give off a bad smell. Sponge-like konjac in such a state is extremely unusable for practical use because it significantly deteriorates the feeling of use, and its improvement has been desired in advance.

The present invention has been made in view of such circumstances, and it is difficult to attract various bacteria in the air or water,
Moreover, it is an object of the present invention to provide an antibacterial and antifungal sponge-like konjac composition which has an effect of suppressing the growth of various bacteria and can be always used in a clean state.

[0005]

In order to achieve the above-mentioned object, the gist of the present invention is to provide a porous body obtained by freezing, thawing and drying konjac, and
0.05 to 3.0 parts by weight of the compound, and / or 0.1 to 5.0 parts by weight of the following (B) compound are included. For example, a paste-like kneaded product obtained by adding a coagulant such as water or calcium hydroxide to a mixture prepared by adding an appropriate amount of the following powder of the compound (A) and / or (B) compound, a dispersion liquid, etc. to the milling of konjac potato The paste-form kneaded product is molded into an appropriate shape, then once frozen, returned to room temperature, thawed, and dried to obtain the sponge-like konjac composition of the present invention. (A) A compound represented by the following general formula (1).

[Chemical 3] (Where R ₁ is hydrogen or -NHCONH (CH ₂ ).
₃ CH ₃ group, R ₂ is thiazolyl group or —NHC00C
H represents a ₃ group) (B) a compound represented by the following general formula (2).

[Chemical 4] (Where M is a monovalent or divalent metal atom, and n is 1 or 2)

Specific examples of the compound (A) include 2- (4-thiazolyl) benzimidazole represented by the following formula:

[Chemical 5] 2-carbomethoxyamino benzimidazole represented by the following formula,

[Chemical 6] Or methyl-1-butylcarbamoyl-2-benzimidazole carbamate represented by the following formula,

[Chemical 7] Etc.

Specific examples of the compound (B) include bis (2-pyridylthio-1-oxide) zinc, bis (2-pyridylthio-1-oxide) manganese and bis (2-pyridylthio-1-oxide). Iron, bis (2-pyridylthio-1-oxide) nickel, bis (2-pyridylthio-1-oxide) barium, bis (2-pyridylthio-1-oxide) copper, bis (2-pyridylthio-)
1-oxide) magnesium, 2-pyridylthio-1-
Sodium oxide, 2-pyridylthio-1-oxide potassium, 2-pyridylthio-1-oxide lithium and the like can be mentioned.

When the above-mentioned (A) compound and / or (B) compound is compounded in the sponge-like konjac composition of the present invention, it is prepared in advance with the powder of the above-mentioned (A) compound and / or (B) compound. Was done (A)
A dispersion liquid of the compound and the compound (B) can be added. In this case, the compounding amount of the compound (A) is 0.05 to 3.0 parts by weight, preferably 0.3 to 1.0 part by weight, as the remaining amount of the compounding relative to 100 parts by weight of the spongy konjac composition. That is, if the compounding residual amount of this compound exceeds 3.0 parts by weight, there is a possibility that safety problems such as strong skin irritation may occur, and if it is less than 0.05 parts by weight, This is because the antifungal effect is lowered and the object of the present invention is not achieved.

The compounding amount of the compound (B) is 0.1 to 5.0 parts by weight, preferably 0.5 to 2.0 parts by weight based on 100 parts by weight of the spongy konjac composition.
Parts by weight. That is, if the compounding residual amount of this compound exceeds 5.0 parts by weight, problems of skin irritation, deterioration of the quality of the spongy konjac composition itself, and the like occur, and conversely, if it is less than 0.1 parts by weight, This is because the antibacterial and antifungal effects are lowered and the object of the present invention is not achieved.

When the spongy konjac composition of the present invention is produced as described above, other additives, regulators, or reinforcing materials such as fibers may be added.

[0011]

EXAMPLES Hereinafter, the present invention will be specifically described with reference to Examples, but prior to this, a method for testing mold and bacteria will be described.

[0012] For the mold test, Aspergillus niger (ATCC 6275), Penicillium citrinum (ATCC 9849), Rhizopus niglycans (SN 32), Cladosporium herbalum (IAMF517), Ketomium globo are prescribed in the mold test. Sum (ATCC
5205 of 5 strains of 6205), Aspergillus niger (ATCC9642), Aspergillus flavus (ATCC9643), Aspergillus vesicorol (ATCC11730), Penicillium funiculosum (ATCC11797), and Ketium globomum (ATCC6205). Use different strains. In addition, four types of strains, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Bacillus subtilis, are used for the bacterial test.

(A) Mold test by agar plating method According to the paint test according to JIS Z 2911, the above 5
Each type of mold is used. First, potato dextrose agar medium is aseptically dispensed into a Petri dish having a diameter of 9 cm to be solidified. Then, the spongy konjac (sample) of each of the examples described below was placed in the center of the Petri dish, and a mixed spore suspension of 5 types of mold fungi was sprayed uniformly on the medium surface and the sample surface, and then the Petri dish was added. Put the lid on the plate. The petri dish is kept at a relative humidity of 95% and a humidity of 28 ± 2 ° C. for 7 to 10 days for culturing.

(B) Bacterial test by agar plate culture method After the above-mentioned four kinds of bacterial strains were preliminarily heat-sterilized,
Inoculate an ordinary agar medium cooled to an appropriate temperature and stir well. Next, this is dispensed into a Petri dish having a diameter of 9 cm to be solidified, and then a sponge-like konjac of each Example described later is placed in the center thereof and the lid is covered. The petri dish is kept at a temperature of 30 ± 1 ° C. for 3 to 5 days to perform culture.

(C) Mold test by the improved agar plate method Each of the above 5 kinds of mold strains is used. Similar to the test method of (a) above, 30 × 30 × 2 was placed on the spongy konjac of each example placed on an agar plate in a Petri dish.
Place a film agar film of mm potato dextrose.
Next, the mold spore suspensions of the five types of mold fungi were uniformly sprayed on the base layer agar, the sample surface and the film agar film, and the Petri dish was covered with a lid, and the temperature was 28 ± 2 ° C. for 7 to 10 days. Incubate.

Evaluation of the above-mentioned tests (a) and (b) ◯: Growth inhibition zone is remarkable Δ: Growth inhibition zone is slightly observed ×: No growth inhibition zone

Evaluation of the above test (C) ◯: There is a zone of inhibition on the base plate agar and no growth of mold or bacteria on the spongy konjac upper film agar △: No zone of inhibition is formed on the base plate agar, but sponge-like Almost no growth of mold or bacteria on the konjac upper film agar ×: No inhibition zone was formed on the base plate agar and growth of mold or bacteria was found on the spongy konjac upper film agar

[0018]

【Example】

Examples 1 to 7 Cut konjac potatoes, dry until the water content becomes about 15% to make coarse powder, and further pulverize this to make finely crushed konjac raw material 30 to 60 times in weight ratio. after kneading by adding water, as shown in the following table 1 2- (4-thiazolyl) benzoimidazole Mita tetrazole 50% dispersion of bis (2-pyridylthio) zinc-1,1 ^'- dioxide 50% dispersion Was blended so that the blending residual amount was a predetermined weight% per final sponge-like konjac to obtain paste-like konjac. To this paste-like konjac, calcium hydroxide was added as a coagulant and placed in a mold to obtain a molded product, which was heated in hot water and then pulled out of the hot water and cut into plates. The plate-like konjac obtained in this manner was once frozen to separate the water and the konjac component in the konjac, and then the mixture was returned to room temperature and thawed and dried to produce a sponge-like konjac composition. Table 1 shows the results of the mold test and the bacterial test described above for this spongy konjac composition.

Except without blending dioxide in the same manner as in the above embodiment sponge-like konjac composition - [0019] Comparative Example 1 2- (4-thiazolyl) benzoimidazole Mita tetrazole and bis (2-pyridylthio) zinc-1,1 ^' It was manufactured, and similarly subjected to a mold test and a bacteria test, and the results are shown in Table 1.

[Table 1]

As shown in Table 1, JIS Z 2911
In the mold test (a) by bis (2-pyridylthio), both the JIS and MIL standard molds
Zinc-1,1 ^'- Examples 4-7 were blended dioxide
The spongy konjac composition has a high mold resistance and is 2
The mold resistance of the spongy konjac compositions of Examples 1 to 3 containing only-(4-thiazolyl) benzimidazole was not recognized. In addition, bacteria test (b)
In even-bis (2-pyridylthio) zinc-1,1 ^', particularly for Staphylococcus aureus and Escherichia coli - Antibacterial effect of dioxide blended is large.

As described above, in the mold test (a) according to JIS Z 2911, the spongy konjac compositions of Examples 1 to 3 containing only 2- (4-thiazolyl) benzimidazole showed good results. However, according to the modified mold test (C) by the agar plate method, Comparative Example 1
No mold resistance is observed at all, but 2-
It has been confirmed that the composition containing (4-thiazolyl) benzimidazole has mold resistance, and that it is confirmed that a sponge-like konjac composition having a mildew-proofing effect can be obtained by mixing only this compound. It was

From the test results of Examples 6 and 7,
2- (4-thiazolyl) benzimidazole and bis (2-pyridylthio) zinc-1,1 ^'- sponge konjac compositions formulated in combination with both dioxides, best antimicrobial, possible to obtain the antifungal effect There was found.

[0023] In the above embodiment, as examples of the compounds to be blended in the present invention, 2- (4-thiazolyl) benzimidazole and bis (2-Birijiruchio) zinc -1,1 ^'- When using dioxide The compounds (A) and (B) represented by the general formulas (1) and (2) are almost the same as those of the above-mentioned Examples shown in Table 1 in the mold resistance and bacterial resistance. It was confirmed that the same effect was exhibited.

[0024]

As described above, since the spongy konjac composition of the present invention has excellent resistance to mold and bacteria, even if it is allowed to stand in a water-containing state, the surface of the mold will be mildew. It can be used in a hygienic condition at all times without the occurrence of odors or the contained water spoiling by bacteria and giving off a bad odor. Furthermore, the sponge-like konjac composition of the present invention is a very practical composition that does not irritate the skin and can be safely used as a cleaning tool or the like.

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Claims (1)

[Claims] 1. A porous body obtained by freezing, thawing and drying konjac, the following compound (A) 0.05 to 3.0:
Parts by weight, and / or the following (B) compound 0.1 to
A sponge-like konjac composition comprising 5.0 parts by weight. (A) A compound represented by the following general formula (1). [Chemical 1] (Where R ₁ is hydrogen or -NHCONH (CH ₂ ).
₃ CH ₃ group, R ₂ is thiazolyl group or —NHC00C
H represents a ₃ group) (B) a compound represented by the following general formula (2). [Chemical 2] (Where M is a monovalent or divalent metal atom, and n is 1 or 2)