JPH05154185A - Blood sample preserving bag - Google Patents
Blood sample preserving bagInfo
- Publication number
- JPH05154185A JPH05154185A JP3350293A JP35029391A JPH05154185A JP H05154185 A JPH05154185 A JP H05154185A JP 3350293 A JP3350293 A JP 3350293A JP 35029391 A JP35029391 A JP 35029391A JP H05154185 A JPH05154185 A JP H05154185A
- Authority
- JP
- Japan
- Prior art keywords
- blood
- tube
- dispensing
- bag
- bag body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008280 blood Substances 0.000 title claims abstract description 44
- 210000004369 blood Anatomy 0.000 title claims abstract description 44
- 238000005070 sampling Methods 0.000 claims abstract description 10
- 229920003002 synthetic resin Polymers 0.000 claims abstract description 6
- 239000000057 synthetic resin Substances 0.000 claims abstract description 6
- 238000012360 testing method Methods 0.000 abstract description 12
- 238000010186 staining Methods 0.000 abstract 1
- 229920001971 elastomer Polymers 0.000 description 7
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 239000003146 anticoagulant agent Substances 0.000 description 3
- 229940127219 anticoagulant drug Drugs 0.000 description 3
- 238000010241 blood sampling Methods 0.000 description 3
- 239000000806 elastomer Substances 0.000 description 3
- -1 poly (ethylene butylene) Polymers 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- 239000012503 blood component Substances 0.000 description 2
- 239000000306 component Substances 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 1
- 229930024421 Adenine Natural products 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 229920002633 Kraton (polymer) Polymers 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 229920006311 Urethane elastomer Polymers 0.000 description 1
- 229960000643 adenine Drugs 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229920002050 silicone resin Polymers 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
Landscapes
- Sampling And Sample Adjustment (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は、供血者より採取した血
液を保管し、例えば試験管等の血液検査器具に分注する
ために使用する保存バッグに関するものである。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a storage bag used for storing blood collected from a donor and dispensing it into blood test instruments such as test tubes.
【０００２】[0002]
【従来技術および発明が解決しようとする課題】本願出
願人は、血液サンプルの保存バッグとして、特願平３−
１６８６７０号に記載の保存バッグを提案した。該保存
バッグはバッグ本体の上端部にサンプリングポ−トを装
着し、該サンプリングポ−トからバッグ本体内に採取し
た血液サンプルを、シリンジにより採血し、続いてシリ
ンジの針を取り外して、シリンジ筒の先端より、あらか
じめ準備した試験管に分注していた。2. Description of the Related Art The applicant of the present invention has proposed a Japanese Patent Application No.
The storage bag described in 168670 was proposed. The storage bag has a sampling port attached to the upper end of the bag body, and a blood sample collected in the bag body from the sampling port is sampled by a syringe, and subsequently, the needle of the syringe is removed to remove the syringe cylinder. It was dispensed from the tip to the test tube prepared in advance.
【０００３】このような保存バッグでは、血液サンプル
を試験管に分注する作業に手間がかかり、またこの間に
採血者、検査担当者の手が汚染される可能性があり必ず
しも好ましくなかった。そこで本発明者は以上の課題を
解決するために鋭意検討を重ねた結果次の発明に到達し
た。[0003] Such a storage bag is not always preferable because it takes a lot of time to dispense a blood sample into a test tube and the hands of a blood sampler and a person in charge of inspection may be contaminated during this time. Therefore, the present inventor has arrived at the next invention as a result of extensive studies to solve the above problems.
【０００４】[0004]
【課題を解決するための手段】本発明は、可撓性合成樹
脂よりなるバッグ本体２と該バッグ本体２の上端部に、
採血針３をその先端に接続し途中にサンプリングポ−ト
４及び連通部材５を配置した採血チュ−ブ６が装着さ
れ、分注ノズル７をその先端に接続し途中に連通部材８
を配置した分注チュ−ブ９を装着した保存バッグ１を提
供するものである。According to the present invention, a bag body 2 made of a flexible synthetic resin and an upper end portion of the bag body 2 are provided.
A blood collection tube 6 having a blood sampling needle 3 connected to its tip and a sampling port 4 and a communication member 5 arranged in the middle is attached, and a dispensing nozzle 7 is connected to the tip thereof and a communication member 8 in the middle thereof.
The present invention provides a storage bag 1 equipped with a dispensing tube 9 in which is arranged.
【０００５】[0005]
【作用】血液を作業者の手を汚すことなく、採血から試
験管への分注に至るまで、クロ−ズドシステムで保存し
移送することができる。The blood can be stored and transferred by the closed system from blood collection to pipetting into a test tube without soiling the hands of workers.
【０００６】[0006]
【実施例】図１は、本発明の保存バッグ１の概略図であ
る。保存バッグ１は可撓性合成樹脂からなるバッグ本体
２とこの上端に装着される採血針３をその先端に接続し
途中にサンプリングポ−ト４及び連通部材５を配置した
採血チュ−ブ６と、分注ノズル７をその先端に接続し途
中に連通部材８を配置した分注チュ−ブ９とから構成さ
れる。1 is a schematic view of a storage bag 1 of the present invention. The storage bag 1 includes a bag main body 2 made of a flexible synthetic resin, a blood sampling needle 3 attached to the upper end of the bag main body 2, a blood sampling tube 6 having a sampling port 4 and a communication member 5 arranged in the middle thereof. , And a dispensing tube 9 in which a dispensing nozzle 7 is connected to the tip of the dispensing nozzle 7 and a communication member 8 is disposed in the middle thereof.
【０００７】前記バッグ本体２を構成する可撓性合成樹
脂は、全血１ｍｌ当り０．１０ｍｌ／２４ｈｒ・ａｔｍ
以上の酸素透過性を有するもの、例えば、軟質塩化ビニ
ル樹脂、軟質塩化ビニル系エラスト−（例えば、商品
名：エスメディカＶＨ：積水化学製）、スチレン系エラ
ストマ−［（例えば、ポリ（エチレンブチレン）ポリス
チレンブロック共重合体（例えば、商品名：クレイトン
Ｇ：シエル化学製、商品名：タフテック：旭化成工業
製）］、ポリプロピレン、エチレン・酢酸ビニル共重合
体（ＥＶＡ）の架橋処理品、オレフィン系エラストマ−
（商品名：ＭＫ−レジン：大日本プラスチック製）、ウ
レタン系エラストマ−（（商品名：ドミナス：日本ポリ
ウレタン製）、ポリエチレンテレフタレ−トまたはその
共重合体、シリコ−ン樹脂等の合成樹脂が使用される。
酸素透過性を上記の範囲に限定したのは血液成分の代謝
による酵素、炭酸ガスを取り入れ、放出を適正レベル以
上にする目的である。The flexible synthetic resin constituting the bag body 2 is 0.10 ml / 24 hr.atm per 1 ml of whole blood.
Those having the above oxygen permeability, for example, soft vinyl chloride resin, soft vinyl chloride elastomer (for example, trade name: Smedica VH: Sekisui Chemical Co., Ltd.), styrene elastomer [(for example, poly (ethylene butylene) Polystyrene block copolymer (for example, trade name: Kraton G: manufactured by Ciel Chemical Co., trade name: Tuftec: manufactured by Asahi Chemical Industry Co., Ltd.)], polypropylene, ethylene / vinyl acetate copolymer (EVA) cross-linked product, olefin elastomer
(Product name: MK-resin: Dainippon Plastics), urethane elastomer ((Product name: Dominus: Nippon Polyurethane), polyethylene terephthalate or its copolymer, synthetic resin such as silicone resin) used.
The oxygen permeability is limited to the above range for the purpose of taking in enzymes and carbon dioxide gas by metabolism of blood components and releasing them at an appropriate level or higher.
【０００８】また、前記バッグ本体２の内部には、血液
および血液成分の保存性を向上させるために、例えば、
ＡＣＤ液（アデニン、クエン酸、ブドウ糖を主成分とす
る）、ＣＰＤ液（クエン酸、ブドウ糖を主成分とす
る）、４％クエン酸ナトリウム水溶液等の抗凝固剤が封
入されている。前記バッグ本体２の容量は、２０ｍｌか
ら８０ｍｌに形成するのが良い。２０ｍｌ以下では、検
査に十分な血液量が確保できず、８０ｍｌ以上では検査
に必要な血液量以上を採血することになり、血液のロス
になるからである。前記サンプリンポ−ト４は、検査用
血液を注入あるいはサンプリングするために使用され
る。In order to improve the preservability of blood and blood components inside the bag body 2, for example,
An anticoagulant such as an ACD solution (containing adenine, citric acid, glucose as a main component), a CPD solution (containing citric acid, glucose as a main component), a 4% sodium citrate aqueous solution, etc. is enclosed. The capacity of the bag body 2 is preferably 20 ml to 80 ml. This is because if the volume is 20 ml or less, a sufficient blood volume for the test cannot be secured, and if it is 80 ml or more, the blood volume more than the blood volume required for the test is collected, resulting in blood loss. The sample port 4 is used for injecting or sampling test blood.
【０００９】前記サンプリンポ−ト４は、検査用血液を
注入あるいはサンプリングするために使用される。また
採血チュ−ブ６と分注チュ−ブ８の途中には必要に応じ
て、クランプ１２、１３が装着されている。The sample port 4 is used for injecting or sampling test blood. If necessary, clamps 12 and 13 are attached in the middle of the blood collection tube 6 and the dispensing tube 8.
【００１０】前記サンプリングポ−ト４は通常使用され
ているいわゆる混注部が使用される。例えば針の穿刺部
に混注ゴムボタン４ａを埋設したものが使用されるが、
特に本発明では、混注ゴムボタン４ａに針を複数回穿刺
して使用する場合もあるので、針を穿刺した後も、混注
ゴムボタン４ａの針の穿刺穴が塞がりやすいように、混
注ゴムボタン４ａを超音波ウェルダ−により圧縮嵌合し
たものが好適である。As the sampling port 4, a so-called mixed injection section which is normally used is used. For example, a needle with a mixed injection rubber button 4a embedded in the puncture portion is used.
Particularly, in the present invention, the mixed injection rubber button 4a may be used by puncturing the needle a plurality of times. Therefore, even after the needle is punctured, the mixed injection rubber button 4a may be easily closed so that the puncture hole of the needle of the mixed injection rubber button 4a is closed. It is preferable that the above is compressed and fitted by an ultrasonic welder.
【００１１】前記採血針３は、供血者に穿刺して固定し
やすいように翼付のものが良い。前記連通部材５、８
は、例えば、チュ−ブ５ａの中に、大径部５ｂと小径部
５ｃからなる連通ピ−スを配置して、大径部と小径部の
薄肉部５ｄを折って開通することにより、血液の流通を
可能にしたものである。次に、本発明の保存バッグの使
用方法を説明する。The blood collecting needle 3 preferably has a wing so that the blood donor can easily puncture and fix the blood donor. The communication members 5, 8
For example, by arranging a communication piece consisting of a large diameter portion 5b and a small diameter portion 5c in the tube 5a and breaking the thin wall portion 5d of the large diameter portion and the small diameter portion to open the blood, The distribution of Next, a method of using the storage bag of the present invention will be described.
【００１２】［採血］ 採血チュ−ブ６下部にチュ−ブル−プ１４を作成し、
クランプ１２を閉じて、連通部材５を切断する。 供血者に採血針３を穿刺し、クランプ１２を開けて血
液をバッグ本体２内に採取し、バッグ本体２内の血液を
抗凝固剤と撹拌混合して、室温（２５°Ｃ）で保存す
る。[Blood collection] A tube group 14 is formed under the blood collection tube 6,
The clamp 12 is closed and the communication member 5 is cut. The donor is punctured with the blood collection needle 3, the clamp 12 is opened to collect the blood in the bag body 2, the blood in the bag body 2 is stirred and mixed with the anticoagulant, and stored at room temperature (25 ° C). .
【００１３】［分注］ 抗凝固剤と混合した血液を収納した保存バッグ１を上
下左右に振とうし、バッグ本体２内の血液をよく混ぜ
る。 クランプ１３を閉じた後、連通部材８を切断し、図２
に示すように分注ノズル７を試験管１５の側壁に付けて
静かに血液を流す（この分注操作は、試験管内の検査液
がＦｉｃｏｌｌ−Ｃｏｎｒａｙ液等の重層の場合、特に
有効である）。[Dispensing] The storage bag 1 containing the blood mixed with the anticoagulant is shaken vertically and horizontally to mix the blood in the bag body 2 well. After closing the clamp 13, the communication member 8 is cut,
As shown in, the dispensing nozzle 7 is attached to the side wall of the test tube 15 to gently flow the blood (this dispensing operation is particularly effective when the test solution in the test tube is a multi-layered Ficoll-Conray solution or the like). .
【００１４】[0014]
【発明の効果】本発明の保存バッグを用いると、採血か
ら分注までの間、手を汚すことなく操作できるので衛生
的である。The storage bag of the present invention is hygienic because it can be operated from blood collection to dispensing without soiling the hands.
【図１】本発明の保存バッグの概略図FIG. 1 is a schematic view of a storage bag of the present invention.
【図２】保存バッグの使用状態図[Figure 2] Usage diagram of storage bag
１ 保存バッグ ２ バッグ本体 ３ 採血針 ４ サンプリングポ−ト ５ 連通部材 ６ 採血チュ−ブ ７ 分注ノズル ８ 連通部材 ９ 分注チュ−ブ 1 Storage bag 2 Bag body 3 Blood collection needle 4 Sampling port 5 Communication member 6 Blood collection tube 7 Dispensing nozzle 8 Communication member 9 Dispensing tube
Claims (1)
該バッグ本体２の上端部に、採血針３をその先端に接続
し途中にサンプリングポ−ト４及び連通部材５を配置し
た採血チュ−ブ６が装着され、分注ノズル７をその先端
に接続し途中に連通部材８を配置した分注チュ−ブ９を
装着したことを特徴とする血液サンプル保存バッグ１
（以下「保存バッグ１」）。1. A bag body 2 made of a flexible synthetic resin, and a blood collection tube in which a blood collection needle 3 is connected to the tip of the bag body 2 at the upper end thereof and a sampling port 4 and a communication member 5 are arranged in the middle thereof. A blood sample storage bag 1 having a tube 6 attached thereto, a dispensing nozzle 7 connected to a tip thereof, and a dispensing tube 9 having a communicating member 8 disposed in the middle thereof.
(Hereafter, "storage bag 1").
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3350293A JP2740992B2 (en) | 1991-12-09 | 1991-12-09 | Blood sample storage bag |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3350293A JP2740992B2 (en) | 1991-12-09 | 1991-12-09 | Blood sample storage bag |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH05154185A true JPH05154185A (en) | 1993-06-22 |
| JP2740992B2 JP2740992B2 (en) | 1998-04-15 |
Family
ID=18409517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3350293A Expired - Lifetime JP2740992B2 (en) | 1991-12-09 | 1991-12-09 | Blood sample storage bag |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2740992B2 (en) |
-
1991
- 1991-12-09 JP JP3350293A patent/JP2740992B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2740992B2 (en) | 1998-04-15 |
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