JPH0471520B2 - - Google Patents

Info

Publication number
JPH0471520B2
JPH0471520B2 JP26750090A JP26750090A JPH0471520B2 JP H0471520 B2 JPH0471520 B2 JP H0471520B2 JP 26750090 A JP26750090 A JP 26750090A JP 26750090 A JP26750090 A JP 26750090A JP H0471520 B2 JPH0471520 B2 JP H0471520B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP26750090A
Other versions
JPH03236794A (en
Inventor
Rarusu Oeshutoberuku Gunnaa
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH40982A priority Critical patent/CH652145A5/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of JPH03236794A publication Critical patent/JPH03236794A/ja
Publication of JPH0471520B2 publication Critical patent/JPH0471520B2/ja
Anticipated expiration legal-status Critical
Application status is Expired - Lifetime legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material Not used, see subgroups
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • C12N5/166Animal cells resulting from interspecies fusion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses, e.g. hepatitis E virus
    • C07K16/1018Orthomyxoviridae, e.g. influenza virus
JP26750090A 1982-01-22 1990-10-03 Expired - Lifetime JPH0471520B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH40982A CH652145A5 (de) 1982-01-22 1982-01-22 Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.

Publications (2)

Publication Number Publication Date
JPH03236794A JPH03236794A (en) 1991-10-22
JPH0471520B2 true JPH0471520B2 (ja) 1992-11-13

Family

ID=4186382

Family Applications (3)

Application Number Title Priority Date Filing Date
JP58009241A Expired - Lifetime JPH0365148B2 (ja) 1982-01-22 1983-01-21
JP26750090A Expired - Lifetime JPH0471520B2 (ja) 1982-01-22 1990-10-03
JP3157731A Expired - Lifetime JPH0789909B2 (ja) 1982-01-22 1991-05-30 ハイブリドーマセルラインの製造法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP58009241A Expired - Lifetime JPH0365148B2 (ja) 1982-01-22 1983-01-21

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP3157731A Expired - Lifetime JPH0789909B2 (ja) 1982-01-22 1991-05-30 ハイブリドーマセルラインの製造法

Country Status (17)

Country Link
US (1) US4634664A (ja)
JP (3) JPH0365148B2 (ja)
AT (1) AT388932B (ja)
CH (1) CH652145A5 (ja)
CY (1) CY1488A (ja)
DE (1) DE3301249C2 (ja)
DK (1) DK23183A (ja)
FI (1) FI83538C (ja)
FR (1) FR2522679B1 (ja)
GB (1) GB2113715B (ja)
HK (1) HK52589A (ja)
IL (1) IL67721A (ja)
IT (1) IT1160468B (ja)
KE (1) KE3884A (ja)
MY (1) MY8700169A (ja)
SE (1) SE502344C2 (ja)
SG (1) SG28189G (ja)

Families Citing this family (151)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1247538A (en) * 1982-05-21 1988-12-27 Mark C. Glassy Human-human hybridomas for solid tumors
US4613576A (en) * 1983-03-09 1986-09-23 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies to cancer cells
EP0148644A3 (en) * 1984-01-06 1987-06-03 Cetus Corporation A novel fusion partner and its products
US4634666A (en) * 1984-01-06 1987-01-06 The Board Of Trustees Of The Leland Stanford Junior University Human-murine hybridoma fusion partner
US4764465A (en) * 1984-04-26 1988-08-16 Cetus Corporation Human monoclonal antibody against group A red blood cells
JPH0720885B2 (ja) * 1985-09-27 1995-03-08 帝人株式会社 単純ヘルペスウイルス感染症の予防又は治療剤
WO1986002092A1 (en) * 1984-09-28 1986-04-10 Teijin Limited Mouse human hybridoma producing antivirus human antibody, process for its preparation, and antivirus human monoclonal antibody
JPS6187630A (en) * 1984-10-08 1986-05-06 Teijin Ltd Human monoclonal antibody to simple herpes virus, and its preparation
US4693975A (en) * 1984-11-20 1987-09-15 The Wistar Institute Human hybridroma fusion partner for production of human monoclonal antibodies
JPH0361428B2 (ja) * 1984-12-28 1991-09-19 Teijin Ltd
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
CH670098B (ja) * 1985-05-23 1989-05-12
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
EP0261233A4 (en) * 1986-04-01 1988-08-29 Genelabs Inc Immortalized virus-specific tissue cells.
AU7281787A (en) * 1986-04-01 1987-10-20 Genelabs Incorporated Immortalized cells which produce tissue-specific products
US5565354A (en) * 1986-09-05 1996-10-15 Sandoz Ltd. Production of human monoclonal antibodies specific for hepatitis B surface antigen
US5646041A (en) * 1987-02-12 1997-07-08 Harfeldt; Elisabeth Monoclonal antibody to herpes simplex virus and cell line producing same
US5001065A (en) * 1987-05-27 1991-03-19 Cetus Corporation Human cell line and triomas, antibodies, and transformants derived therefrom
JPH01101896A (en) * 1987-10-14 1989-04-19 Teijin Ltd Human-monoclonal antibody to fungi of genus candida and production thereof
US5215913A (en) * 1987-11-30 1993-06-01 Roger Williams General Hospital IgG-1 human monoclonal antibody reactive with an HIV-1 antigen and methods of use
IT1226477B (it) * 1988-07-04 1991-01-16 Genetik Mab S R L Linee cellulari n omas quale un mezzo per immortalare cellule produttrici di sostanze di qualunque specie animale.
US5770429A (en) * 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US7041871B1 (en) 1995-10-10 2006-05-09 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
JP2535455B2 (ja) * 1991-02-07 1996-09-18 帝人株式会社 サイトメガロウイルスに対するヒト・モノクロ―ナル抗体を産生するハイブリド―マ
ES2199216T3 (es) * 1991-07-15 2004-02-16 The Wellcome Foundation Limited Produccion de anticuerpos.
JPH05276984A (ja) * 1991-09-05 1993-10-26 Teijin Ltd カンジダに対するヒト・モノクローナル抗体を産生するハイブリドーマ
JPH05260961A (ja) * 1992-05-21 1993-10-12 Teijin Ltd サイトメガロウイルスに対するヒト・モノクローナル抗体を産生するハイブリドーマ
PL302438A1 (en) * 1992-06-26 1994-07-25 Aetsrn Human anti-rh(d) monoclonal antibodies and cellular lines producing them
EP0583980A1 (en) * 1992-08-20 1994-02-23 Eli Lilly And Company Method for generating monoclonal antibodies from rabbits
WO1994011495A1 (en) * 1992-11-06 1994-05-26 Sandoz, Ltd. Production of human monoclonal antibodies active against hepatitis b surface antigen
US5750106A (en) * 1993-01-28 1998-05-12 Novartis Ag Human monoclonal antibodies to cytomegalovirus
US6046310A (en) * 1996-03-13 2000-04-04 Protein Design Labs., Inc. FAS ligand fusion proteins and their uses
AT443141T (de) 1997-02-07 2009-10-15 Us Gov Health & Human Serv Aktivitätsabhänginger neurotropischer faktor iii(adnf iii)
US7964192B1 (en) 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
US6197582B1 (en) * 1998-03-18 2001-03-06 The Trustees Of Columbia University In The City Of New York Development of human monoclonal antibodies and uses thereof
SG147275A1 (en) 1999-06-01 2008-11-28 Elan Pharma Int Ltd Prevention and treatment of amyloidogenic disease
EP1230269A2 (en) * 1999-11-03 2002-08-14 Maxygen, Inc. Antibody diversity generation
US7060802B1 (en) * 2000-09-18 2006-06-13 The Trustees Of Columbia University In The City Of New York Tumor-associated marker
PE05742002A1 (es) 2000-12-06 2002-07-02 Wyeth Corp Anticuerpos humanizados que reconocen el peptido amiloideo beta
US7179892B2 (en) 2000-12-06 2007-02-20 Neuralab Limited Humanized antibodies that recognize beta amyloid peptide
DK1456360T3 (da) 2001-04-19 2015-08-31 Scripps Research Inst Fremgangsmåder og sammensætning til fremstiling af ortogonale TRNA-aminoacyl-TRNA-syntetasepar
US7084257B2 (en) * 2001-10-05 2006-08-01 Amgen Inc. Fully human antibody Fab fragments with human interferon-gamma neutralizing activity
US20030086929A1 (en) * 2001-10-11 2003-05-08 Tso J. Yun Treatment of prostate cancer by inhibitors of ATP synthase
AT541047T (de) 2002-08-01 2012-01-15 Univ California Therapeutische monoklonale antikörper zur neutralisierung von botulinum neurotoxinen
MX2007001679A (es) 2004-08-09 2007-05-23 Elan Pharm Inc Prevencion y tratamiento de la enfermedad sinucleinopatica y amiloidogenica.
TW200509968A (en) 2002-11-01 2005-03-16 Elan Pharm Inc Prevention and treatment of synucleinopathic disease
US8506959B2 (en) 2002-11-01 2013-08-13 Neotope Biosciences Limited Prevention and treatment of synucleinopathic and amyloidogenic disease
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
US20050025763A1 (en) 2003-05-08 2005-02-03 Protein Design Laboratories, Inc. Therapeutic use of anti-CS1 antibodies
US7709610B2 (en) 2003-05-08 2010-05-04 Facet Biotech Corporation Therapeutic use of anti-CS1 antibodies
US7358331B2 (en) 2003-05-19 2008-04-15 Elan Pharmaceuticals, Inc. Truncated fragments of alpha-synuclein in Lewy body disease
ES2632216T3 (es) 2003-05-19 2017-09-11 Prothena Biosciences Limited Fragmentos truncados de la alfa-sinucleína en la enfermedad de cuerpos de Lewy
EP1633312A4 (en) 2003-06-16 2012-09-26 Medimmune Llc Influenza hemagglutinin and neuraminidase variants
BRPI0411475A (pt) 2003-06-18 2006-07-25 Scripps Research Inst adições de código genético de aminoácido reativo não natural
PT2118300E (pt) 2007-02-23 2015-09-22 Univ California Prevenção e tratamento da doença sinucleinopática e amiloidogénica
EP2118300B1 (en) 2007-02-23 2015-05-27 Prothena Biosciences Limited Prevention and treatment of synucleinopathic and amyloidogenic disease
US7935790B2 (en) * 2004-10-04 2011-05-03 Cell Singaling Technology, Inc. Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
US7973134B2 (en) * 2004-07-07 2011-07-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways
CA2568020C (en) 2004-05-25 2015-04-07 Medimmune Vaccines, Inc. Influenza hemagglutinin and neuraminidase variants
US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
BRPI0607374A2 (pt) 2005-01-27 2009-09-01 Childrens Hosp & Res Ct Oakland vacinas de vesìculas baseadas em gna1870 para proteção de amplo espectro contra doenças causadas por neisseria meningitidis
US7700738B2 (en) 2005-01-27 2010-04-20 The Regents Of The University Of California Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
ES2527503T3 (es) 2005-03-08 2015-01-26 Medimmune, Llc Virus influenza reordenantes
DE602006014691D1 (de) * 2005-08-02 2010-07-15 Xbiotech Inc DIAGNOSE, BEHANDLUNG UND PRÄVENTION VON GEFÄSSERKRANKUNGEN MITTELS IL-1alpha-AUTOANTIKÖRPERN
WO2007027906A2 (en) * 2005-08-31 2007-03-08 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
US20090258442A1 (en) * 2006-08-31 2009-10-15 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
US20100151495A9 (en) * 2005-08-31 2010-06-17 Cell Signaling Technolgy, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
DOP2006000277A (es) 2005-12-12 2007-08-31 Bayer Pharmaceuticals Corp Anticuerpos anti mn y métodos para su utilización
WO2007117410A2 (en) 2006-03-31 2007-10-18 Medarex, Inc. Transgenic animals expressing chimeric antibodies for use in preparing human antibodies
US8173425B2 (en) * 2006-04-13 2012-05-08 N{dot over (a)}omasa Yamamoto Fusion partner cells
US20090298093A1 (en) * 2006-04-27 2009-12-03 Roberto Polakiewicz Reagents for the Detection of Protein Phosphorylation in ATM & ATR Kinase Signaling Pathways
US20110008282A1 (en) * 2006-05-15 2011-01-13 Xbiotech, Inc. IL-1alpha immunization induces autoantibodies protective against atherosclerosis
US20100040574A1 (en) * 2006-05-22 2010-02-18 Xbiotech Inc. TREATMENT OF CANCER WITH ANTI-IL-1alpha ANTIBODIES
EP1983002A3 (en) 2007-04-19 2009-03-11 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
JP2009543579A (ja) 2006-07-19 2009-12-10 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア 抗炎症反応のための標的としてのWSX−1/p28
US7939636B2 (en) * 2006-08-11 2011-05-10 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in c-Src signaling pathways
US8652782B2 (en) 2006-09-12 2014-02-18 Longhorn Vaccines & Diagnostics, Llc Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids
US8097419B2 (en) 2006-09-12 2012-01-17 Longhorn Vaccines & Diagnostics Llc Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009
US9481912B2 (en) 2006-09-12 2016-11-01 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and identifying nucleic acid sequences in biological samples
US8440185B2 (en) * 2006-12-26 2013-05-14 The Johns Hopkins University Compositions and methods for the treatment of immunologic disorders
WO2008083239A2 (en) * 2006-12-27 2008-07-10 The Johns Hopkins University Compositions and methods for stimulating an immune response
US20090142342A1 (en) * 2006-12-27 2009-06-04 Johns Hopkins University B7-h4 receptor agonist compositions and methods for treating inflammation and auto-immune diseases
US7989173B2 (en) * 2006-12-27 2011-08-02 The Johns Hopkins University Detection and diagnosis of inflammatory disorders
US20090081659A1 (en) 2007-03-07 2009-03-26 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
EP1975184A3 (en) 2007-03-26 2008-11-26 Cell Signaling Technology, Inc. Serine or threonine phosphorylation sites
US20080238709A1 (en) * 2007-03-28 2008-10-02 Faramarz Vaziri One-way communication apparatus with dynamic key generation
EP1983003A3 (en) 2007-04-19 2009-03-11 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
US7977462B2 (en) 2007-04-19 2011-07-12 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
US20090053831A1 (en) 2007-05-01 2009-02-26 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
AU2008284015B2 (en) 2007-08-03 2014-05-15 Musc Foundation For Research Development Human monoclonal antibodies and methods for producing the same
EP2532676B1 (en) 2007-08-15 2017-03-22 Bayer Pharma Aktiengesellschaft Protease-regulated antibody
US10004799B2 (en) 2007-08-27 2018-06-26 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
EP2185196B1 (en) 2007-08-27 2014-06-11 Longhorn Vaccines & Diagnostics, LLC Immunogenic compositions and methods
CA2701168A1 (en) 2007-10-01 2009-07-09 Longhorn Vaccines & Diagnostics, Llc Biological specimen collection and transport system and methods of use
US8080645B2 (en) 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
US9683256B2 (en) 2007-10-01 2017-06-20 Longhorn Vaccines And Diagnostics, Llc Biological specimen collection and transport system
US20110020941A1 (en) 2007-10-05 2011-01-27 National Institute for Bioprocessing Research and Training Limited Glycosylation markers for pancreatitis, sepsis and pancreatic cancer
US20090099340A1 (en) * 2007-10-12 2009-04-16 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
US20090203043A1 (en) 2007-11-21 2009-08-13 Peter Hornbeck Protein phosphorylation by basophilic serine/threonine kinases in insulin signaling pathways
US20090169549A1 (en) * 2007-12-19 2009-07-02 The Board Of Regents Of The University Of Texas System Conformational isomers of alpha-synuclein, antibodies thereto and methods of their manufacture and use
US20090220991A1 (en) * 2008-02-29 2009-09-03 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
WO2009126306A2 (en) 2008-04-10 2009-10-15 Cell Signaling Technology, Inc. Compositions and methods for detecting egfr mutations in cancer
EP3085773A3 (en) * 2008-05-30 2016-11-23 XBiotech, Inc Uses of il-1 alpha antibodies
CN102112878A (zh) * 2008-06-06 2011-06-29 SC World株式会社 用于检测流感病毒的装置
WO2010006144A2 (en) 2008-07-11 2010-01-14 Medlmmune, Llc. Influenza hemagglutinin and neuraminidase variants
AU2009291536B2 (en) * 2008-09-12 2012-08-16 Xbiotech, Inc. Targeting pathogenic monocytes
US20100260752A1 (en) 2009-01-23 2010-10-14 Biosynexus Incorporated Opsonic and protective antibodies specific for lipoteichoic acid of gram positive bacteria
CN102361649A (zh) 2009-02-12 2012-02-22 米迪缪尼有限公司 流感血凝素和神经氨酸酶变体
WO2010129609A2 (en) 2009-05-07 2010-11-11 The Regents Of The University Of California Antibodies and methods of use thereof
US9005616B2 (en) 2009-08-31 2015-04-14 Amplimmune, Inc. Methods and compositions for the inhibition of transplant rejection
US20110311547A1 (en) 2010-06-18 2011-12-22 Xbiotech, Inc. Arthritis Treatment
SG187853A1 (en) 2010-08-23 2013-03-28 Xbiotech Inc Treatment for neoplastic diseases
US9228026B2 (en) 2010-12-06 2016-01-05 Seattle Genetics, Inc. Humanized antibodies to LIV-1 and use of same to treat cancer
ES2697056T3 (es) 2011-04-01 2019-01-21 Xbiotech Inc Tratamiento para patologías dermatológicas
JP6204915B2 (ja) 2011-09-23 2017-09-27 エックスバイオテク,インコーポレイテッドXbiotech,Inc. 悪液質治療
US9598462B2 (en) 2012-01-26 2017-03-21 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
US20130309223A1 (en) 2012-05-18 2013-11-21 Seattle Genetics, Inc. CD33 Antibodies And Use Of Same To Treat Cancer
UA105278C2 (ru) 2012-09-06 2014-04-25 Інститут Біології Клітини Нан України Способ получения каталитически активных антител (абзимов) с сиалидазной активностью
US9545441B2 (en) 2012-09-18 2017-01-17 Xbiotech, Inc. Treatment of diabetes
ES2701406T3 (es) 2012-10-08 2019-02-22 Prothena Biosciences Ltd Anticuerpos que reconocen alfa-sinucleína
EP2970453A4 (en) 2013-03-13 2016-12-07 Prothena Biosciences Ltd Tau immunotherapy
EP3016683A4 (en) 2013-07-05 2017-02-22 University of Washington through its Center for Commercialization Soluble mic neutralizing monoclonal antibody for treating cancer
WO2015004632A1 (en) 2013-07-12 2015-01-15 Neotope Biosciences Limited Antibodies that recognize iapp
WO2015004633A1 (en) 2013-07-12 2015-01-15 Neotope Biosciences Limited Antibodies that recognize islet-amyloid polypeptide (iapp)
TW201623331A (en) 2014-03-12 2016-07-01 Prothena Biosciences Ltd Anti-MCAM antibodies and associated methods of use
KR20160127825A (ko) 2014-03-12 2016-11-04 프로테나 바이오사이언시즈 리미티드 항-mcam 항체 및 관련된 사용 방법
WO2015136471A1 (en) 2014-03-12 2015-09-17 Prothena Biosciences Limited Anti-laminin4 antibodies specific for lg1-3
US10059761B2 (en) 2014-03-12 2018-08-28 Prothena Biosciences Limited Anti-Laminin4 antibodies specific for LG4-5
US20170174777A1 (en) 2014-04-08 2017-06-22 Prothena Bioscience Limited Blood-Brain Barrier Shuttles Containing Antibodies Recognizing Alpha-Synuclein
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
US20160075772A1 (en) 2014-09-12 2016-03-17 Regeneron Pharmaceuticals, Inc. Treatment of Fibrodysplasia Ossificans Progressiva
CN107208076A (zh) 2014-10-17 2017-09-26 科达制药 丁酰胆碱酯酶两性离子聚合物缀合物
WO2018007924A2 (en) 2016-07-02 2018-01-11 Prothena Biosciences Limited Anti-transthyretin antibodies
WO2018007922A2 (en) 2016-07-02 2018-01-11 Prothena Biosciences Limited Anti-transthyretin antibodies
TW201636372A (en) 2015-01-28 2016-10-16 Prothena Biosciences Ltd Anti-transthyretin antibodies
TW201632554A (en) 2015-01-28 2016-09-16 Prothena Biosciences Ltd Anti-transthyretin antibodies
WO2018007923A2 (en) 2016-07-02 2018-01-11 Prothena Biosciences Limited Anti-transthyretin antibodies
TW201636371A (en) 2015-01-28 2016-10-16 Prothena Biosciences Ltd Anti-transthyretin antibodies
EP3288976A1 (en) 2015-04-29 2018-03-07 Regeneron Pharmaceuticals, Inc. Treatment of fibrodysplasia ossificans progressiva
US9976136B2 (en) 2015-05-14 2018-05-22 Longhorn Vaccines And Diagnostics, Llc Rapid methods for the extraction of nucleic acids from biological samples
WO2017046774A2 (en) 2015-09-16 2017-03-23 Prothena Biosciences Limited Use of anti-mcam antibodies for treatment or prophylaxis of giant cell arteritis, polymyalgia rheumatica or takayasu's arteritis
JP2018530540A (ja) 2015-09-16 2018-10-18 プロセナ バイオサイエンシーズ リミテッド 巨細胞動脈炎、リウマチ性多発筋痛症又は高安動脈炎の処置又は予防のための抗mcam抗体の使用
WO2017149513A1 (en) 2016-03-03 2017-09-08 Prothena Biosciences Limited Anti-mcam antibodies and associated methods of use
WO2017153953A1 (en) 2016-03-09 2017-09-14 Prothena Biosciences Limited Use of anti-mcam antibodies for treatment or prophylaxis of granulomatous lung diseases
WO2017153955A1 (en) 2016-03-09 2017-09-14 Prothena Biosciences Limited Use of anti-mcam antibodies for treatment or prophylaxis of granulomatous lung diseases
CN109219615A (zh) 2016-05-02 2019-01-15 普罗塞纳生物科学有限公司 识别tau的抗体
CA3022765A1 (en) 2016-05-02 2017-11-09 Prothena Biosciences Limited Antibodies recognizing tau
WO2017208210A1 (en) 2016-06-03 2017-12-07 Prothena Biosciences Limited Anti-mcam antibodies and associated methods of use
KR20190025689A (ko) 2016-07-06 2019-03-11 프로테나 바이오사이언시즈 리미티드 전체 및 s129 인산화된 알파-시누클레인을 검출하기 위한 검정
WO2019018744A1 (en) 2017-07-21 2019-01-24 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Neisseria meningitidis immunogenic compositions
WO2019086331A2 (en) 2017-11-02 2019-05-09 Bayer Aktiengesellschaft Bispecific antibodies binding alk-1 and bmpr-2

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2757169A1 (de) * 1977-12-22 1979-07-05 Hoechst Ag Verfahren zur gewinnung insulin produzierender tierischer zellen
ZA8006506B (en) * 1979-11-01 1981-09-30 Bio Response Inc A method for production of monoclonal antibodies
GB2079313A (en) * 1980-07-07 1982-01-20 Nat Res Dev Improvements in or relating to rat myeloma cell lines
EP0043718B1 (en) * 1980-07-07 1984-11-28 National Research Development Corporation Improvements in or relating to cell lines
WO1982001461A1 (en) * 1980-07-18 1982-05-13 Leland Stanford Junior Univ Human hybridomas,precursors and products
JPS586475B2 (ja) * 1980-08-23 1983-02-04 Hayashibara Seibutsu Kagaku Kenkyusho Kk
JPS6045849B2 (ja) * 1980-08-25 1985-10-12 Hayashibara Takeshi
JPS585671B2 (ja) * 1980-08-27 1983-02-01 Hayashibara Seibutsu Kagaku Kenkyusho Kk
JPS5756877B2 (ja) * 1980-08-27 1982-12-01 Hayashibara Seibutsu Kagaku Kenkyusho Kk
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4529694A (en) * 1982-04-16 1985-07-16 The Children's Medical Center Corporation Cell fusion

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DK23183D0 (da) 1983-01-20
HK52589A (en) 1989-07-07
DE3301249A1 (de) 1983-09-22
CH652145A5 (de) 1985-10-31
IT8319234D0 (it) 1983-01-21
IL67721D0 (en) 1983-05-15
IL67721A (en) 1986-04-29
JPH0789909B2 (ja) 1995-10-04
SE8300290D0 (sv) 1983-01-20
DE3301249C2 (ja) 1990-04-05
FI830190A0 (fi) 1983-01-20
GB8301384D0 (en) 1983-02-23
SE502344C2 (sv) 1995-10-09
FR2522679A1 (fr) 1983-09-09
DK23183A (da) 1983-07-23
JPS58128323A (en) 1983-07-30
MY8700169A (en) 1987-12-31
FI830190A (ja)
SE8300290L (sv) 1983-07-23
SG28189G (en) 1989-08-11
FR2522679B1 (fr) 1986-05-09
US4634664A (en) 1987-01-06
FI83538B (fi) 1991-04-15
FI830190L (fi) 1983-07-23
ATA19583A (de) 1989-02-15
AT388932B (de) 1989-09-25
IT1160468B (it) 1987-03-11
GB2113715A (en) 1983-08-10
JPH0365148B2 (ja) 1991-10-09
JPH0690753A (ja) 1994-04-05
GB2113715B (en) 1986-06-04
FI83538C (fi) 1991-07-25
KE3884A (en) 1989-08-11
CY1488A (en) 1989-12-08
FI830190D0 (ja)
JPH03236794A (en) 1991-10-22

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