JPH0394660A - Powdery nutrition composition - Google Patents
Powdery nutrition compositionInfo
- Publication number
- JPH0394660A JPH0394660A JP1232102A JP23210289A JPH0394660A JP H0394660 A JPH0394660 A JP H0394660A JP 1232102 A JP1232102 A JP 1232102A JP 23210289 A JP23210289 A JP 23210289A JP H0394660 A JPH0394660 A JP H0394660A
- Authority
- JP
- Japan
- Prior art keywords
- powdered
- composition
- emulsion
- oil
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 55
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 29
- 230000035764 nutrition Effects 0.000 title abstract description 3
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims abstract description 25
- 150000002632 lipids Chemical class 0.000 claims abstract description 15
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 14
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000001384 succinic acid Substances 0.000 claims abstract description 12
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 11
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 11
- 235000013343 vitamin Nutrition 0.000 claims abstract description 11
- 239000011782 vitamin Substances 0.000 claims abstract description 11
- 229940088594 vitamin Drugs 0.000 claims abstract description 11
- 229930003231 vitamin Natural products 0.000 claims abstract description 11
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 9
- 239000011707 mineral Substances 0.000 claims abstract description 9
- 238000000354 decomposition reaction Methods 0.000 claims abstract description 8
- 239000000843 powder Substances 0.000 claims description 11
- 150000001720 carbohydrates Chemical class 0.000 claims description 9
- 235000014633 carbohydrates Nutrition 0.000 claims description 9
- 239000006185 dispersion Substances 0.000 abstract description 22
- 239000000839 emulsion Substances 0.000 abstract description 22
- 150000003722 vitamin derivatives Chemical class 0.000 abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 18
- 239000003921 oil Substances 0.000 description 15
- 235000019198 oils Nutrition 0.000 description 15
- 239000003925 fat Substances 0.000 description 12
- 235000019197 fats Nutrition 0.000 description 11
- 239000007788 liquid Substances 0.000 description 11
- 239000000047 product Substances 0.000 description 10
- 238000002156 mixing Methods 0.000 description 9
- 235000014113 dietary fatty acids Nutrition 0.000 description 8
- 229930195729 fatty acid Natural products 0.000 description 8
- 239000000194 fatty acid Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 235000018102 proteins Nutrition 0.000 description 8
- 235000021056 liquid food Nutrition 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 230000001804 emulsifying effect Effects 0.000 description 5
- -1 fatty acid ester Chemical class 0.000 description 5
- 150000004665 fatty acids Chemical class 0.000 description 5
- 239000004615 ingredient Substances 0.000 description 5
- 235000015097 nutrients Nutrition 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 239000003761 preservation solution Substances 0.000 description 4
- 235000015872 dietary supplement Nutrition 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 238000000265 homogenisation Methods 0.000 description 3
- 229920001353 Dextrin Polymers 0.000 description 2
- 239000004375 Dextrin Substances 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 2
- 235000019864 coconut oil Nutrition 0.000 description 2
- 239000003240 coconut oil Substances 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 235000005687 corn oil Nutrition 0.000 description 2
- 239000002285 corn oil Substances 0.000 description 2
- 235000019425 dextrin Nutrition 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000004945 emulsification Methods 0.000 description 2
- 235000021323 fish oil Nutrition 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 235000014593 oils and fats Nutrition 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 238000001694 spray drying Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 102000011632 Caseins Human genes 0.000 description 1
- 108010076119 Caseins Proteins 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 108010028690 Fish Proteins Proteins 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 108010070551 Meat Proteins Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 108010011756 Milk Proteins Proteins 0.000 description 1
- 102000014171 Milk Proteins Human genes 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 235000019484 Rapeseed oil Nutrition 0.000 description 1
- 108010073771 Soybean Proteins Proteins 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 1
- 239000010775 animal oil Substances 0.000 description 1
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 description 1
- 235000015278 beef Nutrition 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 229940021722 caseins Drugs 0.000 description 1
- 210000000991 chicken egg Anatomy 0.000 description 1
- 150000001860 citric acid derivatives Chemical class 0.000 description 1
- 150000002016 disaccharides Chemical class 0.000 description 1
- 239000008344 egg yolk phospholipid Substances 0.000 description 1
- 229940068998 egg yolk phospholipid Drugs 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000012041 food component Nutrition 0.000 description 1
- 239000013022 formulation composition Substances 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000010699 lard oil Substances 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 229960004488 linolenic acid Drugs 0.000 description 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 description 1
- 150000004667 medium chain fatty acids Chemical class 0.000 description 1
- 235000021239 milk protein Nutrition 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 210000004798 organs belonging to the digestive system Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 230000006920 protein precipitation Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000019710 soybean protein Nutrition 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野】
本発明は新規な粉末栄養組成物、さらに詳しくは、通常
の食事を摂取することのできない小児や老人、あるいは
手術前や手術後の患者などの栄養補給に用いられる粉末
栄養組戊物に関するものである。[Detailed Description of the Invention] [Field of Industrial Application] The present invention provides a novel powdered nutritional composition, more specifically, for use in children and the elderly who are unable to take regular meals, or patients before or after surgery. This invention relates to a powdered nutritional composition used for nutritional supplementation.
[従来の技術]
従来、通常の食事を摂取することのできない小児や老人
、あるいは手術前や手術後の患者などに対する栄養補給
の方法としては、経口栄養組戒物や経管栄養組或物を用
いる経腸的栄養補給法及び経静脈栄養組戒物を用いる避
腸的栄養補給法が知られている。[Prior Art] Traditionally, oral feeding formulas and tube feeding formulas have been used as a method of nutritional support for children and the elderly who are unable to consume regular meals, as well as patients before and after surgery. Enteral feeding methods using parenteral nutritional supplements and enteral feeding methods using parenteral nutritional supplements are known.
前者の経腸的栄養補給法において用いられる栄養組戊物
は、栄養成分のバランスがとれ、かつ高カロリーである
とともに、消化吸収が良好で、下痢や腹部膨張感を起こ
さないことが必要であることから、通常天然食品やその
分解物などの種々の栄養剤を混合し、タンパク質、糖質
、脂質、ビタミン、ミネラルなどを含有する高カロリー
で栄養的にバランスのとれたものに調合されている。The nutritional composition used in the former enteral feeding method must have well-balanced nutritional components and high calorie content, be easily digested and absorbed, and not cause diarrhea or abdominal distension. Therefore, it is usually mixed with various nutrients such as natural foods and their decomposed products to form a high-calorie, nutritionally balanced product containing proteins, carbohydrates, lipids, vitamins, minerals, etc. .
このような栄養組成物の中で粉末状のものは、例えば脂
質にあらかじめ乳化剤を溶解させておき、このものとタ
ンパク質、炭水化物などを水に加え、乳化させてから熱
風乾燥することにより調製することができる。前記のタ
ンパク質と乳化剤は乳化液の乳化安定化に関与し、特に
乳化剤は粉末栄養組戊物を水に加えて液状にした場合、
その液の乳化安定性に大きく関与する。Among such nutritional compositions, powdered ones can be prepared by, for example, dissolving an emulsifier in lipids in advance, adding the emulsifier, proteins, carbohydrates, etc. to water, emulsifying the composition, and then drying with hot air. I can do it. The above proteins and emulsifiers are involved in stabilizing the emulsion, especially when the powdered nutritional composition is added to water and made into a liquid.
It is greatly involved in the emulsion stability of the liquid.
ところで、このような粉末栄養組.rlt物は患者など
に投与するために通常温湯に加え、液状にしたのち、そ
の調製液を経口やチューブ又はカテーテルを通して、静
匡点滴と同じ要領で経腸的に投与される。したがって、
該調製液は患者などへの投与が終了するまで、数時間室
温にて放置されたり、低温で2日間程度保存される場合
がある。このため、該調製液は、その調製時点や室温又
は低温で保存した際に脂質のクリーミング、オイルオ7
及びタンパク質の沈殿などか起こらないように均質な乳
化分散状態を保持することが必要である。By the way, this kind of powdered nutritional group. In order to administer RLT products to patients, they are usually added to warm water to make a liquid, and then the prepared liquid is administered enterally orally or through a tube or catheter in the same manner as a static drip. therefore,
The preparation may be left at room temperature for several hours or stored at a low temperature for about 2 days until administration to the patient is completed. For this reason, the preparation liquid may undergo lipid creaming, oil odor removal, etc. at the time of preparation or when stored at room temperature or low temperature.
It is also necessary to maintain a homogeneous emulsified dispersion state to prevent precipitation of proteins.
[発明か解決しようとする課題]
本発明者らは、このような事情のもとで、先に乳化剤と
して、重合度か3〜lOのポリグリセリンと脂肪酸との
エステルであって、そのエステル結合の数が1〜10の
ポリグリセリン脂肪酸エステルを用いた経管栄養組成物
を見い出したか(特開昭60−193928号公報)、
本発明は、水に加え液状にした場合に、より乳化分散安
定性に優れる、タンパク質及び/又はその分解物、糖質
、脂質、ビタミン及ひミネラルを主成分とする粉末栄養
組或物を提供することを目的としてなされたものである
。[Problem to be solved by the invention] Under these circumstances, the present inventors first developed an ester of polyglycerin with a polymerization degree of 3 to 1O and a fatty acid as an emulsifier, and the ester bond thereof. have discovered a tube feeding composition using a polyglycerin fatty acid ester having a number of 1 to 10 (Japanese Patent Application Laid-Open No. 193928/1983);
The present invention provides a powdered nutritional composition containing protein and/or its decomposition products, carbohydrates, lipids, vitamins, and minerals as main components, which has superior emulsification and dispersion stability when added to water and made into a liquid form. It was done for the purpose of
[課題を解決するための手段]
本発明者らは、前記の好ましい性質を有する粉末栄養組
戊物を開発すべく鋭意研究を重ねた結果、乳化剤として
コハク酸モノグリセリドを特定の割合で含有する粉末m
或物が、水に加えて液状にした場合、従来製品よりも脂
質の乳化安定性及びタンバタ質の分散安定性に優れ、そ
の目的を達成しうろことを見い出し、この知見に基づい
て本発明を完成するに至った。[Means for Solving the Problem] As a result of intensive research to develop a powdered nutritional composition having the above-mentioned preferable properties, the present inventors have developed a powder containing succinic acid monoglyceride as an emulsifier in a specific proportion. m
We have discovered that when a certain substance is added to water and made into a liquid, it has superior emulsion stability of lipids and dispersion stability of tambata compared to conventional products, achieving the objective.Based on this knowledge, we have developed the present invention. It was completed.
すなわち、本発明は、タンパク質及び/又はその分解物
、糖質、脂質、ビタミン及びミ不ラルを主成分とする粉
末栄養組戊物において、乳化剤としてコハク酸モノグリ
セリド0,02〜5.00重量%を含有することをn@
とする粉末栄養組戒物を提供するものである。That is, the present invention provides a powdered nutritional composition containing proteins and/or their decomposition products, carbohydrates, lipids, vitamins, and minerals as main components, in which 0.02 to 5.00% by weight of succinic acid monoglyceride is used as an emulsifier. Contains n@
It provides powdered nutritional supplements.
以下、本発明を詳細に説明する。The present invention will be explained in detail below.
本発明組或物において用いられるコハク酸モノグリセリ
ドは、グリセリンと炭素数12〜20の脂肪酸との脂肪
酸モノグリセリドを、さらにコハク酸でエステル化した
ものであって、単独で用いてもよいし、他の乳化剤、例
えば卵黄リン脂質、モノグリセリド、ショ糖脂肪酸エス
テル、ポリグリセリン脂肪酸エステル、コハク酸以外の
有機酸モノグリセリドなとと組み合わせて用いてもよい
。The succinic acid monoglyceride used in the composition of the present invention is obtained by further esterifying a fatty acid monoglyceride of glycerin and a fatty acid having 12 to 20 carbon atoms with succinic acid, and may be used alone or with other fatty acids. It may be used in combination with emulsifiers such as egg yolk phospholipids, monoglycerides, sucrose fatty acid esters, polyglycerin fatty acid esters, and organic acid monoglycerides other than succinic acid.
このコハク酸モノグリセリドは、粉末組成物中に0.0
2〜5.OO重量%、好ましくは0.50〜3.00重
量%の割合で含有していることが必要である。この含有
量が0.02重量%未満では乳化分散安定性の向上効果
が十分に発揮されないし、5.00重量%を超えるとそ
の量の割には該効果の向上があまり認められない。This succinic monoglyceride is present in the powder composition at 0.0
2-5. It is necessary to contain 0% by weight, preferably 0.50 to 3.00% by weight. If this content is less than 0.02% by weight, the effect of improving emulsion dispersion stability will not be sufficiently exhibited, and if it exceeds 5.00% by weight, the improvement in this effect will not be recognized much considering the amount.
本発明組戒物は、タンパク質及び/又はその分解物、糖
質、脂質、ビタミン及びミ不ラルを主成分とするもので
あって、人体に必要な栄養分を十分に供給することがで
きる。The composition of the present invention is mainly composed of protein and/or its decomposition products, carbohydrates, lipids, vitamins, and minerals, and can sufficiently supply nutrients necessary for the human body.
本発明組成物に用いられるタンパク質やその分解物とし
ては、消化しやすく、栄養の高いもの、例えば鶏卵タン
パク質、乳タンパク質、大豆タンパク質、魚夕冫パク質
、肉タンパク質、カゼイン類及びこれらの酵素分解物な
どが挙げられる。これらの夕冫バク質やその分解物は1
種用いてもよいし、2種以上を組み合わせて用いてもよ
く、その配合量は粉末組戊物に対し、通常10〜40重
量%の範囲で選ばれる。The proteins and their decomposition products used in the composition of the present invention include those that are easily digestible and highly nutritious, such as chicken egg protein, milk protein, soybean protein, fish protein, meat protein, caseins, and enzymatic decomposition thereof. Examples include things. These evening bacteria and their decomposition products are 1
A seed may be used or two or more types may be used in combination, and the blending amount is usually selected within the range of 10 to 40% by weight based on the powder composition.
本発明組成物において用いられる糖質としては、例えば
デンプン、デキストリン、あるいはブドウ糖や果糖など
の単糖類、マルトースや乳糖などの二糖類などが挙げら
れる。これらの糖質は1種用いてもよいし、2種以上を
組み合わせて用いてもよく、その配合量は粉末組成物に
対し、通常50〜80重量%の範囲で選はれる。Examples of carbohydrates used in the composition of the present invention include starch, dextrin, monosaccharides such as glucose and fructose, and disaccharides such as maltose and lactose. One type of these carbohydrates may be used, or two or more types may be used in combination, and the blending amount thereof is usually selected within the range of 50 to 80% by weight based on the powder composition.
本発明組或物において用いられる脂質としては、例えば
リノール酸、リノレン酸などの脂肪酸、大豆油、コーン
油、ナタ不油、ヤシ油、ラード、牛脂、魚油などの動植
物油脂、中鎖脂肪酸トリグリセリドなどの加工油脂など
が挙げられる。これらの脂質はl種用いてもよいし、2
ffl以上を組み合わせて用いてもよく、その配合量は
、通常粉末組戒物に対し、5〜35重量%の範囲で選ば
れる。Examples of the lipids used in the composition of the present invention include fatty acids such as linoleic acid and linolenic acid, animal and vegetable oils and fats such as soybean oil, corn oil, rapeseed oil, coconut oil, lard, beef tallow, and fish oil, and medium-chain fatty acid triglycerides. Examples include processed oils and fats. These lipids may be used in one type, or two types may be used.
ffl or more may be used in combination, and the blending amount thereof is usually selected in the range of 5 to 35% by weight based on the powder composition.
微量成分であるビタミン類及びミネラル類は栄養上必要
な量を適宜添加される。まl;、本発明組戊物には、必
要に応じ、リン酸塩、クエン酸塩なとの乳化安定剤、果
汁、フレーバー類などを添加してもよい。Vitamins and minerals, which are trace components, are added in nutritionally necessary amounts as appropriate. Also, emulsion stabilizers such as phosphates and citrates, fruit juice, flavors, etc. may be added to the composition of the present invention, if necessary.
本発明の粉末栄養組戊物は、前記配合材料を水に加え乳
化したのち、この乳化液を噴霧乾燥法などにより乾燥し
て、粉末状にすることにより調製することができる。こ
の際、コノ)ク酸モノグリセリドは、あらかじめ脂質に
溶解させておいて用いてもよいし、水に溶解させて用い
てもよい。The powdered nutritional composition of the present invention can be prepared by adding the above ingredients to water and emulsifying the mixture, and then drying the emulsion by spray drying or the like to form a powder. At this time, cono)citric acid monoglyceride may be used after being dissolved in lipid beforehand, or may be used after being dissolved in water.
また、本発明の粉末栄養組放物は、あらかじめ粉末油脂
をつくり、これとその他の粉末材料を粉一粉混合して調
製するのが有利である。すなわち、脂質、コハク酸モノ
グリセリドとタンパク質及び糖質の一部とを用い、これ
らを水に加えて乳化処理したのち、噴霧乾燥などで乾燥
して粉末油脂を得る。この場合、コハク酸モノグリセリ
ドは本発明組戊物に含有される全量が用いられる。この
ようにして得られた粉末油脂は、水に加えて液状にした
場合に、乳化分散安定性が良好で、室温に数時間、ある
いは低温で2日間程度放置した場合においても均質な乳
化分散状態を示す。この粉末油脂と残りの粉末配合材料
とを粉一粉混合することにより、本発明の粉末栄養組成
物が得られる。Moreover, it is advantageous for the powdered nutritional composition of the present invention to be prepared by preparing a powdered fat or oil in advance and mixing it with other powdered ingredients. That is, using lipids, succinic acid monoglyceride, proteins, and a portion of carbohydrates, these are added to water and emulsified, and then dried by spray drying or the like to obtain powdered fats and oils. In this case, the entire amount of succinic acid monoglyceride contained in the composition of the present invention is used. The powdered oil obtained in this way has good emulsion dispersion stability when added to water and made into a liquid, and maintains a homogeneous emulsion dispersion state even when left at room temperature for several hours or at low temperature for about 2 days. shows. The powdered nutritional composition of the present invention can be obtained by thoroughly mixing this powdered fat and oil with the remaining powdered ingredients.
本発明の粉末栄養組戊物は、使用時に固形分濃度が通常
5〜40重量%、好ましくは20〜25重量%になるよ
うに、水や温湯に加えて乳化液を調製したのち、経口や
チューブなどにより、胃、腸などの消化器官に簡便かつ
迅速に供給することができる。The powdered nutritional composition of the present invention is prepared by adding it to water or hot water to prepare an emulsion so that the solid content concentration is usually 5 to 40% by weight, preferably 20 to 25% by weight, and then administered orally. It can be easily and quickly supplied to digestive organs such as the stomach and intestines using a tube or the like.
[実施例】
次に、実施例により本発明をさらに詳細に説明するが、
本発明はこれらの例によってなんら限定されるものでは
ない。[Example] Next, the present invention will be explained in more detail with reference to Examples.
The present invention is not limited in any way by these examples.
実施例1
第1表の配合組成(I)の材料100重量部に対し、水
2150重量部を加え、70゜Cに昇温した。この際、
コハク酸モノグリセリドは、あらかじめ大豆油、中鎖脂
肪酸トリグリセリドに溶解させたのち加えた。Example 1 2150 parts by weight of water was added to 100 parts by weight of the material of composition (I) in Table 1, and the temperature was raised to 70°C. On this occasion,
Succinic acid monoglyceride was dissolved in soybean oil and medium chain fatty acid triglyceride in advance and then added.
この混合液を75℃で15分間予備乳化したのち、1段
目200kg/cm2、2段目5 0 kg/ cm”
の2段階均質化法で均質処理して乳化液を得、次いでこ
の乳化液を噴霧乾燥機で乾燥し、粉末油脂を得 I二
。After pre-emulsifying this mixture at 75°C for 15 minutes, the first stage was 200 kg/cm2 and the second stage was 50 kg/cm.
A two-step homogenization method is used to obtain an emulsion, and this emulsion is then dried in a spray dryer to obtain a powdered fat or oil.
.
次に、この粉末油脂20重量部に対し、第1表の配合組
成(n)の粉末材料80重量部を粉一粉混合により配合
して、粉末栄養組戊物を調製した。Next, 80 parts by weight of the powder material having the formulation composition (n) in Table 1 was blended with 20 parts by weight of this powdered oil and fat by powder-to-powder mixing to prepare a powdered nutritional composition.
なお、ビタミンミックスとミ不ラルミックスは第2表に
示す割合で配合したものを用いた。In addition, the vitamin mix and miraru mix were used in the proportions shown in Table 2.
このようにして得られた粉末栄養組成物1009に、温
湯を全量で445mlになるように加えて撹拌し、乳化
分散液を調製した。このものはlkcal/mQの人工
流動食として用いることができた。Warm water was added to the thus obtained powdered nutritional composition 1009 to a total amount of 445 ml and stirred to prepare an emulsified dispersion. This product could be used as an artificial liquid food with lkcal/mQ.
この乳化分散液は、良好な乳化分散状態を示しI;。ま
た室温で8時間、及び5°Cで2日間放置した場合でも
良好な乳化分散状態を示し、これらの保存液は調製直後
のものと栄養的及び品質的に全く差がなく、人工流動食
として用いることができtこ 。This emulsified dispersion liquid exhibited a good emulsified dispersion state. In addition, even when left at room temperature for 8 hours and at 5°C for 2 days, a good emulsification and dispersion state was observed, and these preservation solutions were nutritionally and qualitatively the same as those immediately after preparation, and could be used as artificial liquid foods. It can be used.
(以下余白)
第
1
表
実施例2〜4、比較例1〜4
第3表に示す乳化剤を用いて実施例1と同様にして粉末
油脂及び粉末栄養組戊物を得、同様な試験を行い、その
結果を第4表に示した。(Leaves below) Table 1 Examples 2 to 4, Comparative Examples 1 to 4 Powdered fats and oils and powdered nutritional compositions were obtained in the same manner as in Example 1 using the emulsifiers shown in Table 3, and the same tests were conducted. The results are shown in Table 4.
なお、実施例及び比較例の乳化剤の配合量による全配合
量が100gになるようにするための調整は、デキスト
リンの量を調整することによって行った。It should be noted that adjustments were made so that the total amount of emulsifiers in Examples and Comparative Examples was 100 g by adjusting the amount of dextrin.
第3表の結果から、本発明に係る乳化剤を使用した実施
例のものは、粉末油脂及び粉末栄養組戊物の乳化液にお
いて乳化安定性が著しく優れていることが明らかである
。From the results in Table 3, it is clear that the examples using the emulsifier according to the present invention have extremely excellent emulsion stability in emulsions of powdered oils and fats and powdered nutritional compositions.
(以下余白)
実施例5
第4表の配合組戊(1)の材料100重量部に対し、水
2150重量部を加え、70℃に昇温しI;。この際、
コハク酸モノグリセリドは、あらかじめ、ラード、ヤシ
油の配合油に溶解させたのち加えた。(Left below) Example 5 2150 parts by weight of water was added to 100 parts by weight of the material of formulation (1) in Table 4, and the temperature was raised to 70°C. On this occasion,
Succinic acid monoglyceride was dissolved in advance in a blended oil of lard and coconut oil, and then added.
この混合液を75℃で15分間予備乳化したのち、1段
目3 0 0 kg/ cm2、2段目5 0 kg/
cm2の2段階均質化法で均質処理して乳化液を得、
次いでこの乳化液を噴霧乾燥機で乾燥し、粉末油脂を得
た。After pre-emulsifying this mixture at 75°C for 15 minutes, 300 kg/cm2 in the first stage and 50 kg/cm2 in the second stage.
cm2 homogenized using a two-step homogenization method to obtain an emulsion;
Next, this emulsion was dried with a spray dryer to obtain a powdered fat or oil.
次に、この粉末油脂に第4表に示す配合組戊(II)の
材料を、この表に示す割合で粉一粉混合により配合し、
粉末栄養組成物を調製した。なおビタミンミックスとミ
不ラルミックスは第2表に示す割合で配合しt;ものを
用いた。Next, the ingredients of the blending composition (II) shown in Table 4 are blended into this powdered oil and fat in the proportions shown in this table by powder-to-powder mixing,
A powdered nutritional composition was prepared. The vitamin mix and mineral mix were mixed in the proportions shown in Table 2.
このようにして得られた粉末栄養i或物100gに温湯
を全量で405m(lになるように加え、撹拌して乳化
分散液を調製した。このものはlkcan/mQの人工
流動食として用いることができた。To 100 g of the powdered nutrient I thus obtained, warm water was added to make a total of 405 ml (l) and stirred to prepare an emulsified dispersion. This was used as an artificial liquid food for lkcan/mQ. was completed.
この乳化分散液を室温で8時間、及び5℃で2日間放置
した場合、良好な乳化分散状態を保ち、これらの保存液
は、調製直後のものと品質的に全く差がなく、人工流動
食として用いることができIこ 。When this emulsified dispersion was left at room temperature for 8 hours and at 5°C for 2 days, it maintained a good emulsified dispersion state, and these preserved solutions showed no difference in quality from those immediately after preparation, and were used as artificial liquid food. It can be used as a.
(以下余白)
第
4
表
実施例6
第5表に示す配合組戊(I)の材料100重量部に対し
て、水2150重量部を加え、70゜Cに昇温した。こ
の際、クエン酸モノグリセリドはあらかじめコーン油、
魚油の配合油に溶解させたのち加え、またコハク酸モノ
グリセリドは水に加え、溶解させた。(The following is a blank space) Table 4 Example 6 To 100 parts by weight of the material of formulation (I) shown in Table 5, 2150 parts by weight of water was added and the temperature was raised to 70°C. At this time, citric acid monoglyceride is added in advance to corn oil,
Fish oil was added after being dissolved in blended oil, and succinic acid monoglyceride was added to water and dissolved.
この混合液を70゜Cで15分間予備乳化したのち、1
段目2 5 0 kg/ cm”、2段目5 0 kg
7 cm2の2段階均質化法で均質処理して乳化液を得
、次いでこの乳化液をrIx霧乾燥機で乾燥し、粉末油
脂を得 Iこ 。After pre-emulsifying this mixture at 70°C for 15 minutes,
2nd stage 50 kg/cm”, 2nd stage 50 kg
The emulsion was homogenized using a two-step homogenization method using 7 cm2, and then the emulsion was dried using an rIx fog dryer to obtain a powdered fat or oil.
次にこの粉末油脂に、第5表に示す配合組戊(I[)の
材料をこの表に示す割合で粉一粉混合により配合し、粉
末栄養組成物を調製した。なお、ビタミンミックスとミ
不ラルミンクスは第2表に示す割合で配合しt;ものを
用いた。Next, the ingredients of the formulation (I[) shown in Table 5 were mixed into this powdered oil and fat in the proportions shown in this table by powder-to-powder mixing to prepare a powdered nutritional composition. Incidentally, the vitamin mix and miraruminx were mixed in the proportions shown in Table 2.
このようにして得られI;粉末栄養組戊物1009に温
湯を全量で433mQになるように加え、撹拌して乳化
分散液を調製した。このものはlkcxll/nilの
人工流動食として用いることかできtこ。Warm water was added to the powdered nutritional composition 1009 thus obtained so that the total amount was 433 mQ, and the mixture was stirred to prepare an emulsified dispersion. This can be used as an artificial liquid food for lkcxll/nil.
この乳化分散液を室温で8時間及び5°Cで2日間放置
した場合、良好な乳化分散状態を保ち、これらの保存液
は、調製直後のものと品質的に全く差がなく、人工流動
食として用いることができlこ 。When this emulsified dispersion was left at room temperature for 8 hours and at 5°C for 2 days, it maintained a good emulsified dispersion state, and these preserved solutions showed no difference in quality from those immediately after preparation, and were used as artificial liquid food. It can be used as a.
また、前記粉末油脂を用いて、同様に乳化分散液を調製
し、この液を保存した場合にも良好な乳化分散状態を示
した。Further, when an emulsified dispersion liquid was prepared in the same manner using the powdered oil and fat, and this liquid was stored, a good emulsified dispersion state was exhibited.
(以下余白)
第
5
表
[発明の効果]
本発明の粉末栄養組戊物は、特定の乳化剤を用いること
により、従来のものにはみられない良好な乳化分散安定
性を示し、本発明は、
(1)本発明の粉末栄養組成物の乳化液は、均質な乳化
液分散状態を示し、室温に数時間、あるいは低温で2日
間程度保存した場合においても均質な乳化分欣状態を示
すことから、経腸的な投与方法において、これらの保存
液を栄養分の均一な状態で投与することができる利点、
及び
(2)前記保存液は、脂質粒子が凝集することなく、そ
の大きさか細かい状態のまま維持されているため、保存
液の栄養分の消化吸収は良好で、患者に投与した場合に
下痢が起こりにくく、十分な栄養補給が可能である利点
を有している。(The following is a blank space) Table 5 [Effects of the Invention] By using a specific emulsifier, the powdered nutritional composition of the present invention exhibits good emulsion dispersion stability that is not seen in conventional compositions. (1) The emulsion of the powdered nutritional composition of the present invention exhibits a homogeneous emulsion dispersion state, and exhibits a homogeneous emulsion dispersion state even when stored at room temperature for several hours or at low temperature for about 2 days. Therefore, in the enteral administration method, the advantage is that these preservation solutions can be administered in a uniform state of nutrients,
and (2) the lipid particles in the preservation solution do not aggregate and maintain their size or fineness, so the nutrients in the preservation solution are easily digested and absorbed, and when administered to a patient, diarrhea does not occur. It has the advantage that it is difficult to eat and can provide sufficient nutrition.
Claims (1)
タミン及びミネラルを主成分とする粉末栄養組成物にお
いて、乳化剤としてコハク酸モノグリセリド0.02〜
5.00重量%を含有することを特徴とする粉末栄養組
成物。1. In powdered nutritional compositions containing protein and/or its decomposition products, carbohydrates, lipids, vitamins, and minerals as main components, succinic acid monoglyceride 0.02 to 0.02 as an emulsifier.
A powder nutritional composition characterized in that it contains 5.00% by weight.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1232102A JPH0394660A (en) | 1989-09-07 | 1989-09-07 | Powdery nutrition composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1232102A JPH0394660A (en) | 1989-09-07 | 1989-09-07 | Powdery nutrition composition |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH0394660A true JPH0394660A (en) | 1991-04-19 |
Family
ID=16934039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1232102A Pending JPH0394660A (en) | 1989-09-07 | 1989-09-07 | Powdery nutrition composition |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH0394660A (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08231411A (en) * | 1995-01-13 | 1996-09-10 | Clintec Nutrition Co | Method for feeding nutrition to aged patient |
US5732237A (en) * | 1993-12-24 | 1998-03-24 | Fujitsu Ten Limited | Security system for audio equipment where identification data from a compact disc is stored in memory |
US6569445B2 (en) | 2000-12-05 | 2003-05-27 | Pbm Pharmaceuticals, Inc. | Food bars containing nutritional supplements and anti-constipation and regularity maintaining-agents |
WO2007071261A2 (en) * | 2005-12-21 | 2007-06-28 | Palsgaard A/S | Carboxylic acid esters of mono- and di-glycerides as a dispersing agent |
WO2007087805A1 (en) * | 2006-02-03 | 2007-08-09 | Palsgaard A/S | Carboxylic acid esters of mono- and di-glycerides as a dispersing agent |
US9439885B2 (en) | 2008-06-03 | 2016-09-13 | Mead Johnson Nutrition Company | Method for inhibiting the growth of bacteria |
JPWO2018179953A1 (en) * | 2017-03-30 | 2020-02-06 | テルモ株式会社 | High calorie nutrition composition and package |
-
1989
- 1989-09-07 JP JP1232102A patent/JPH0394660A/en active Pending
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5732237A (en) * | 1993-12-24 | 1998-03-24 | Fujitsu Ten Limited | Security system for audio equipment where identification data from a compact disc is stored in memory |
US5835015A (en) * | 1993-12-24 | 1998-11-10 | Fujitsu Ten Limited | Security system for audio equipment |
US5864528A (en) * | 1993-12-24 | 1999-01-26 | Fujitsu Ten Limited | Security system for audio equipment |
JPH08231411A (en) * | 1995-01-13 | 1996-09-10 | Clintec Nutrition Co | Method for feeding nutrition to aged patient |
US6569445B2 (en) | 2000-12-05 | 2003-05-27 | Pbm Pharmaceuticals, Inc. | Food bars containing nutritional supplements and anti-constipation and regularity maintaining-agents |
WO2007071261A2 (en) * | 2005-12-21 | 2007-06-28 | Palsgaard A/S | Carboxylic acid esters of mono- and di-glycerides as a dispersing agent |
WO2007071261A3 (en) * | 2005-12-21 | 2008-06-05 | Palsgaard As | Carboxylic acid esters of mono- and di-glycerides as a dispersing agent |
WO2007087805A1 (en) * | 2006-02-03 | 2007-08-09 | Palsgaard A/S | Carboxylic acid esters of mono- and di-glycerides as a dispersing agent |
US9439885B2 (en) | 2008-06-03 | 2016-09-13 | Mead Johnson Nutrition Company | Method for inhibiting the growth of bacteria |
JPWO2018179953A1 (en) * | 2017-03-30 | 2020-02-06 | テルモ株式会社 | High calorie nutrition composition and package |
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