JPH02184626A - Blood platelet coagulation inhibiting agent - Google Patents

Blood platelet coagulation inhibiting agent

Info

Publication number
JPH02184626A
JPH02184626A JP342889A JP342889A JPH02184626A JP H02184626 A JPH02184626 A JP H02184626A JP 342889 A JP342889 A JP 342889A JP 342889 A JP342889 A JP 342889A JP H02184626 A JPH02184626 A JP H02184626A
Authority
JP
Grant status
Application
Patent type
Prior art keywords
tea
component
gallate
leaves
extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP342889A
Inventor
Isao Mukai
Chuichi Takeo
Hiroko Tsutsumisaka
Original Assignee
Itouen:Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Abstract

PURPOSE: To obtain a blood platelet coagulation inhibiting agent having blood platelet coagulation inhibiting activity and high safety and suitable to be applied for a long period to prevent thrombosis, atheromatous arteriosclerosis, etc., by using epigallocatechin gallate or epicatechin gallate as an active component.
CONSTITUTION: The objective agent contains, as an active component, epigallocatechin gallate or epicatechin gallate separated from a soluble extract of tea leaves (e.g. green tea, oolong tea or black tea) or from purified soluble extract. The active component is prepared most preferably by adding about 20-40l of hot water to 1kg of tea leaves, decocting for about 10-30min, optionally pressing the leaves and freeze-drying the obtained juice. The tea leaf extract prepared by the above method contains about 30% of the active component. Tea catechins are produced by extracting tea leaves with hot water or a hydrophilic organic solvent in the same manner as above, extracting and removing natural polymers from the extract and further extracting with an organic solvent.
COPYRIGHT: (C)1990,JPO&Japio
JP342889A 1989-01-10 1989-01-10 Blood platelet coagulation inhibiting agent Pending JPH02184626A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP342889A JPH02184626A (en) 1989-01-10 1989-01-10 Blood platelet coagulation inhibiting agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP342889A JPH02184626A (en) 1989-01-10 1989-01-10 Blood platelet coagulation inhibiting agent

Publications (1)

Publication Number Publication Date
JPH02184626A true true JPH02184626A (en) 1990-07-19

Family

ID=11557107

Family Applications (1)

Application Number Title Priority Date Filing Date
JP342889A Pending JPH02184626A (en) 1989-01-10 1989-01-10 Blood platelet coagulation inhibiting agent

Country Status (1)

Country Link
JP (1) JPH02184626A (en)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04352726A (en) * 1990-08-17 1992-12-07 Nikko Kyodo Co Ltd Arterial sclerosis-preventing agent and functional food having arterial sclerosis-preventing activity
FR2709965A1 (en) * 1993-09-13 1995-03-24 Hur Kye Sung pharmaceutical compositions having antithrombotic activity and process for their preparation.
US6114019A (en) * 1996-06-28 2000-09-05 International Business Machines Corporation Circuit board assemblies having filled vias free from bleed-out
EP1103550A1 (en) * 1999-11-16 2001-05-30 F. Hoffmann-La Roche Ag Process for concentrating catechin solutions using membranes
US6524630B2 (en) * 2000-03-22 2003-02-25 Mars, Incorporated Use of cocoa procyanidins combined with acelylsalicyclic acid as an anti-platelet therapy
US6696485B1 (en) 1996-04-02 2004-02-24 Mars, Incorporated Procyanidin and cyclo-oxygenase modulator compositions
JP2005162685A (en) * 2003-12-04 2005-06-23 Taiyo Kagaku Co Ltd Antithrombotic composition
JP2005179251A (en) * 2003-12-19 2005-07-07 Taiyo Kagaku Co Ltd Composition for inhibiting platelet aggregation
JP2005296000A (en) * 2004-03-15 2005-10-27 Shirako:Kk New health food and drink containing marine alga
US7112714B2 (en) * 2004-11-01 2006-09-26 Leber Claudia K Topical wound dressing and method of making same
US7115656B2 (en) 1996-04-02 2006-10-03 Mars, Incorporated Compositions for, and methods of, anti-platelet therapy
JPWO2007020917A1 (en) * 2005-08-18 2009-02-26 国立大学法人徳島大学 Utrophin production of enhancing sustainable agent and processed foods using the same
WO2009059928A1 (en) 2007-11-05 2009-05-14 Unilever Plc Process for purifying compounds from tea
US7608288B2 (en) * 2002-03-25 2009-10-27 Council Of Scientific & Industrial Research Caffeine fraction obtained from tea leaves and a method for inducing Agrobacterium tumefaciens-mediated genetic transformation in plants using said caffeine fraction
US8088424B2 (en) 2007-11-05 2012-01-03 Conopco, Inc., Process for manufacturing tea products
US8273395B2 (en) 2007-11-05 2012-09-25 Conopco, Inc. Process for manufacturing tea products
US9078455B2 (en) 2010-03-25 2015-07-14 Conopco, Inc. Process for manufacturing tea products

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04352726A (en) * 1990-08-17 1992-12-07 Nikko Kyodo Co Ltd Arterial sclerosis-preventing agent and functional food having arterial sclerosis-preventing activity
FR2709965A1 (en) * 1993-09-13 1995-03-24 Hur Kye Sung pharmaceutical compositions having antithrombotic activity and process for their preparation.
JPH07258103A (en) * 1993-09-13 1995-10-09 Hu Kye Sung Antithrombotic agent and production thereof
US6696485B1 (en) 1996-04-02 2004-02-24 Mars, Incorporated Procyanidin and cyclo-oxygenase modulator compositions
US7115656B2 (en) 1996-04-02 2006-10-03 Mars, Incorporated Compositions for, and methods of, anti-platelet therapy
US6114019A (en) * 1996-06-28 2000-09-05 International Business Machines Corporation Circuit board assemblies having filled vias free from bleed-out
EP1103550A1 (en) * 1999-11-16 2001-05-30 F. Hoffmann-La Roche Ag Process for concentrating catechin solutions using membranes
US6524630B2 (en) * 2000-03-22 2003-02-25 Mars, Incorporated Use of cocoa procyanidins combined with acelylsalicyclic acid as an anti-platelet therapy
US7608288B2 (en) * 2002-03-25 2009-10-27 Council Of Scientific & Industrial Research Caffeine fraction obtained from tea leaves and a method for inducing Agrobacterium tumefaciens-mediated genetic transformation in plants using said caffeine fraction
US7879371B2 (en) 2002-03-25 2011-02-01 Council Of Scientific & Industrial Research Caffeine fraction obtained from tea leaves and a method for inducing Agrobacterium tumefaciens-mediated genetic transformation in plants using said caffeine fraction
JP2005162685A (en) * 2003-12-04 2005-06-23 Taiyo Kagaku Co Ltd Antithrombotic composition
JP2005179251A (en) * 2003-12-19 2005-07-07 Taiyo Kagaku Co Ltd Composition for inhibiting platelet aggregation
JP2005296000A (en) * 2004-03-15 2005-10-27 Shirako:Kk New health food and drink containing marine alga
US7112714B2 (en) * 2004-11-01 2006-09-26 Leber Claudia K Topical wound dressing and method of making same
JPWO2007020917A1 (en) * 2005-08-18 2009-02-26 国立大学法人徳島大学 Utrophin production of enhancing sustainable agent and processed foods using the same
WO2009059928A1 (en) 2007-11-05 2009-05-14 Unilever Plc Process for purifying compounds from tea
US8088424B2 (en) 2007-11-05 2012-01-03 Conopco, Inc., Process for manufacturing tea products
US8273395B2 (en) 2007-11-05 2012-09-25 Conopco, Inc. Process for manufacturing tea products
US9078455B2 (en) 2010-03-25 2015-07-14 Conopco, Inc. Process for manufacturing tea products

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