JPH01153622A - Composition for oral cavity - Google Patents
Composition for oral cavityInfo
- Publication number
- JPH01153622A JPH01153622A JP62313261A JP31326187A JPH01153622A JP H01153622 A JPH01153622 A JP H01153622A JP 62313261 A JP62313261 A JP 62313261A JP 31326187 A JP31326187 A JP 31326187A JP H01153622 A JPH01153622 A JP H01153622A
- Authority
- JP
- Japan
- Prior art keywords
- copper
- oleoresin
- oil
- alkali metal
- oleorange
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 18
- 210000000214 mouth Anatomy 0.000 title description 4
- 239000005749 Copper compound Substances 0.000 claims abstract description 16
- 150000001880 copper compounds Chemical class 0.000 claims abstract description 16
- OCUCCJIRFHNWBP-IYEMJOQQSA-L Copper gluconate Chemical compound [Cu+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O OCUCCJIRFHNWBP-IYEMJOQQSA-L 0.000 claims abstract description 15
- 229940108925 copper gluconate Drugs 0.000 claims abstract description 15
- -1 alkali metal salt Chemical class 0.000 claims abstract description 14
- 229910052783 alkali metal Inorganic materials 0.000 claims abstract description 12
- FWBOFUGDKHMVPI-UHFFFAOYSA-K dicopper;2-oxidopropane-1,2,3-tricarboxylate Chemical compound [Cu+2].[Cu+2].[O-]C(=O)CC([O-])(C([O-])=O)CC([O-])=O FWBOFUGDKHMVPI-UHFFFAOYSA-K 0.000 claims abstract description 10
- 240000002943 Elettaria cardamomum Species 0.000 claims abstract description 5
- 235000019502 Orange oil Nutrition 0.000 claims abstract description 5
- 235000005300 cardamomo Nutrition 0.000 claims abstract description 5
- 239000010502 orange oil Substances 0.000 claims abstract description 5
- 244000147568 Laurus nobilis Species 0.000 claims abstract description 4
- 235000017858 Laurus nobilis Nutrition 0.000 claims abstract description 4
- 235000019501 Lemon oil Nutrition 0.000 claims abstract description 4
- 235000005212 Terminalia tomentosa Nutrition 0.000 claims abstract description 4
- 239000010501 lemon oil Substances 0.000 claims abstract description 4
- 239000008601 oleoresin Substances 0.000 claims description 18
- RUVINXPYWBROJD-ONEGZZNKSA-N trans-anethole Chemical compound COC1=CC=C(\C=C\C)C=C1 RUVINXPYWBROJD-ONEGZZNKSA-N 0.000 claims description 8
- 240000004160 Capsicum annuum Species 0.000 claims description 4
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 claims description 4
- 235000007265 Myrrhis odorata Nutrition 0.000 claims description 4
- 240000004760 Pimpinella anisum Species 0.000 claims description 4
- 235000012550 Pimpinella anisum Nutrition 0.000 claims description 4
- 229940011037 anethole Drugs 0.000 claims description 4
- 239000001926 citrus aurantium l. subsp. bergamia wright et arn. oil Substances 0.000 claims description 4
- RUVINXPYWBROJD-UHFFFAOYSA-N para-methoxyphenyl Natural products COC1=CC=C(C=CC)C=C1 RUVINXPYWBROJD-UHFFFAOYSA-N 0.000 claims description 4
- IMACFCSSMIZSPP-UHFFFAOYSA-N phenacyl chloride Chemical compound ClCC(=O)C1=CC=CC=C1 IMACFCSSMIZSPP-UHFFFAOYSA-N 0.000 claims description 4
- 240000006927 Foeniculum vulgare Species 0.000 claims description 3
- 235000004204 Foeniculum vulgare Nutrition 0.000 claims description 3
- 239000001279 citrus aurantifolia swingle expressed oil Substances 0.000 claims description 3
- 235000019606 astringent taste Nutrition 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 6
- 239000002324 mouth wash Substances 0.000 abstract description 5
- 229940051866 mouthwash Drugs 0.000 abstract description 5
- 239000000796 flavoring agent Substances 0.000 abstract description 4
- 235000019634 flavors Nutrition 0.000 abstract description 3
- 239000004615 ingredient Substances 0.000 abstract description 2
- 239000000551 dentifrice Substances 0.000 abstract 2
- 244000270834 Myristica fragrans Species 0.000 abstract 1
- 235000009421 Myristica fragrans Nutrition 0.000 abstract 1
- 239000001702 nutmeg Substances 0.000 abstract 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 10
- 239000000606 toothpaste Substances 0.000 description 9
- 229940034610 toothpaste Drugs 0.000 description 7
- 235000011187 glycerol Nutrition 0.000 description 5
- 206010006326 Breath odour Diseases 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- ULDHMXUKGWMISQ-UHFFFAOYSA-N carvone Chemical compound CC(=C)C1CC=C(C)C(=O)C1 ULDHMXUKGWMISQ-UHFFFAOYSA-N 0.000 description 4
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 4
- 208000032139 Halitosis Diseases 0.000 description 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000001525 mentha piperita l. herb oil Substances 0.000 description 3
- 229940041616 menthol Drugs 0.000 description 3
- 235000019477 peppermint oil Nutrition 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 239000005973 Carvone Substances 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 239000000679 carrageenan Substances 0.000 description 2
- 235000010418 carrageenan Nutrition 0.000 description 2
- 229920001525 carrageenan Polymers 0.000 description 2
- 229940113118 carrageenan Drugs 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- RBLGLDWTCZMLRW-UHFFFAOYSA-K dicalcium;phosphate;dihydrate Chemical compound O.O.[Ca+2].[Ca+2].[O-]P([O-])([O-])=O RBLGLDWTCZMLRW-UHFFFAOYSA-K 0.000 description 2
- 239000001683 mentha spicata herb oil Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 2
- 235000019721 spearmint oil Nutrition 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 2
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 1
- 244000215068 Acacia senegal Species 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 108010001682 Dextranase Proteins 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- AYRXSINWFIIFAE-SCLMCMATSA-N Isomaltose Natural products OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)[C@@H](O)[C@@H](O)[C@@H]1O AYRXSINWFIIFAE-SCLMCMATSA-N 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940112822 chewing gum Drugs 0.000 description 1
- 235000015218 chewing gum Nutrition 0.000 description 1
- 229940061607 dibasic sodium phosphate Drugs 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- DLRVVLDZNNYCBX-RTPHMHGBSA-N isomaltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-RTPHMHGBSA-N 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 230000007505 plaque formation Effects 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 229940085605 saccharin sodium Drugs 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 239000007909 solid dosage form Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
Description
【発明の詳細な説明】
産東上例■朋光更
本発明はグルコン酸銅及びそのアルカリ金属塩並びにク
エン酸銅及びそのアルカリ金属塩から選ばれる銅化合物
の配合により、優れた口臭予防及び除去効果を有すると
共に、かかる銅化合物の配合に基づく収れん性を改善し
た口腔用組成物に関する。[Detailed description of the invention] Santo upper example ■ Tomomitsu Sara The present invention has excellent halitosis prevention and removal effects by blending a copper compound selected from copper gluconate and its alkali metal salts, and copper citrate and its alkali metal salts. The present invention relates to an oral cavity composition which has improved astringency based on the combination of such a copper compound.
従来の び 日が しようとする司 占従来、グ
ルコン酸銅、クエン酸銅等の銅化合物に抗菌効果、口臭
除去効果、歯垢形成阻止効果があることが知られており
、銅化合物を配合した口腔用組成物も種々提案されてい
る（米国特許筒３．０４４，９３９号、同第３，５６５
，９３３号、同第３，６５．５，８．６８号、同第４，
１１２，０６６号、特開昭５６．７１６９６１９号、同
第５６−１６９６２０号、同第６１−、．１．４３３１
７号、同第６２−１４２，１０９号、同第６２−．１６
４６１．．４号公報）。Traditionally, copper compounds such as copper gluconate and copper citrate are known to have antibacterial effects, bad breath removal effects, and plaque formation inhibiting effects. Various oral compositions have also been proposed (U.S. Pat. Nos. 3,044,939 and 3,565).
, No. 933, No. 3, 65.5, 8.68, No. 4,
No. 112,066, JP-A-56-7169619, JP-A No. 56-169620, JP-A No. 61-, . 1.4331
No. 7, No. 62-142, 109, No. 62-. 16
461. ．． Publication No. 4).
しかしながら、これらの銅化合物を配合した口腔用組成
物は、銅に由来する収れん性があり、使用感が悪いとい
う問題がある。However, oral compositions containing these copper compounds have astringent properties derived from the copper, and have a problem of poor usability.
を すやこめの−び
本発明者らは、優れた口臭予防及び除去効果を有し、し
かも銅化合物の配合に基づく収れん性の改善された使用
感のよい口腔用組成物につき種々検討を行なった結果、
グルコン酸銅及びそのアルカリ金属塩並びにクエン酸銅
及びそのアルカリ金属塩から選ばれる１種又は２種以上
の銅化合物と、カルダモンオレオレジン、ローレルオレ
オレジン、ナツメグオレオレジン、ピメントオレオレジ
ン、フェンネルオレオレジン、アニスオレオレジン、ベ
ルガモツトオイル、アネトール、オレンジオイル、レモ
ンオイル、ライムオイルから選ばれる１種又は２種以上
の成分とを併用した場合、グルコン酸銅、クエン酸銅、
それらのアルカリ金属塩の配合により生じる口腔用組成
物の収れん性が確実 。The present inventors have conducted various studies on an oral composition that has excellent halitosis prevention and removal effects, has improved astringency based on the combination of a copper compound, and is comfortable to use. As a result,
One or more copper compounds selected from copper gluconate and its alkali metal salts and copper citrate and its alkali metal salts, and cardamom oleoresin, laurel oleoresin, nutmeg oleoresin, pimento oleoresin, and fennel oleoresin. , anise oleoresin, bergamot oil, anethole, orange oil, lemon oil, lime oil, when used in combination with one or more ingredients selected from copper gluconate, copper citrate,
The astringency of the oral composition produced by the combination of these alkali metal salts is ensured.
に改善され、優れた使用感を与えることを知見し、本発
明をなすに至ったものである。The present invention has been made based on the findings that the material has been improved to provide an excellent feeling of use.
以下、本発明につき更に詳しく説明する。The present invention will be explained in more detail below.
本発明に係る口腔用組成物は、上述したように銅化合物
としてグルコン酸銅及びそのアルカリ金属塩並びにクエ
ン酸銅及びそのアルカリ金属塩から選ばれる１種又は２
種以上の銅化合物を配合するものである。As mentioned above, the oral composition according to the present invention contains one or two copper compounds selected from copper gluconate and its alkali metal salts, and copper citrate and its alkali metal salts.
This method contains more than one type of copper compound.
上記銅化合物の配合量は０．００００１〜２％（重量％
、以下同じ）、特に０．００１〜５％とすることができ
、本発明によれば銅化合物を比較的多く配合しても良好
な使用感を有する。The content of the above copper compound is 0.00001 to 2% (wt%
, hereinafter the same), particularly from 0.001 to 5%, and according to the present invention, even if a relatively large amount of the copper compound is blended, a good usability can be obtained.
本発明は上述した銅化合物の収れん性を改善するため、
オレオレジンとしてカルダモンオレオレジン、ローレル
オレオレジン、ナツメグオレオレジン、ピメントオレオ
レジン、フェンネルオレオレジン、アニスオレオレジン
、アクセント香料としてベルガモツトオイル、アネトー
ル、オレンジオイル、レモンオイル、ライムオイルの１
種又は２種以上を配合する。The present invention improves the astringency of the above-mentioned copper compound,
As oleoresin, cardamom oleoresin, laurel oleoresin, nutmeg oleoresin, pimento oleoresin, fennel oleoresin, anise oleoresin; as accent fragrance, one of bergamot oil, anethole, orange oil, lemon oil, and lime oil.
Mix one species or two or more species.
これらの香味成分の配合量は、組成物全体の１０−５〜
１％、特に０．０００５〜０．２％とすることができる
。The blending amount of these flavor components is 10-5 to 10-5 of the total composition.
1%, especially 0.0005-0.2%.
なお、本発明の口腔用組成物には上記香味成分に加えて
他の香料を配合することは差支えない。Note that, in addition to the above-mentioned flavor components, other flavoring agents may be added to the oral cavity composition of the present invention.
本発明に係る口腔用組成物は、練歯磨、潤製歯磨、液状
歯磨等の歯磨類、マウスウォッシュ、トローチ、うがい
用錠剤、チューインガムなど、種々の用途に応じ、ペー
スト状、液状、粉粒状、固型状等の剤型に調製し得るが
、特に歯磨類、マウスウォッシュとして好ましく用いる
ことができる。The oral composition according to the present invention can be used in various forms such as paste, liquid, powder, granule, etc., such as toothpaste, moisturized toothpaste, liquid toothpaste, mouthwash, troche, gargling tablet, chewing gum, etc. Although it can be prepared into a solid dosage form, it can be particularly preferably used as a toothpaste or mouthwash.
この場合口腔用組成物の他の成分として□は、その目的
等に□より通常使用される適宜な成分を配合することが
できる。例えば練歯磨の場合であれば、□ 研磨剤、
粘結剤、保湿剤、界面活性剤、甘味剤、防腐剤、各種有
効成分などが配合され得る。In this case, as other components of the oral composition, □ can be blended with appropriate components that are commonly used for the purpose. For example, in the case of toothpaste, □ abrasive,
Binder, humectant, surfactant, sweetener, preservative, various active ingredients, etc. may be added.
ｌ匪例羞果
本発明の口腔用組成物は、グルコン酸銅、クエン酸銅又
はそれらのアルカリ金属塩の配合により優れた口臭予防
、除去効果を有すると共に、これら銅化合物による収れ
ん性が抑制され、良好な使用感を有するものである。The oral composition of the present invention has excellent halitosis prevention and removal effects due to the combination of copper gluconate, copper citrate, or their alkali metal salts, and the astringency caused by these copper compounds is suppressed. , it has a good usability.
次に実験例を示し、本発明の効果を具体的に示す。Next, experimental examples will be shown to concretely demonstrate the effects of the present invention.
〔実験例１〕
下記処方の練歯磨を調製し、専門パネラ−１０名により
これらの練歯磨で歯を磨いた後の収れん性を下記基準に
従って評価した。結果を第１表に示す。なお、結果は下
記各評点に評価した人数で示す。[Experimental Example 1] Toothpastes having the following formulations were prepared, and ten expert panelists evaluated the astringency of these toothpastes after brushing their teeth according to the following criteria. The results are shown in Table 1. The results are shown in terms of the number of people who rated each score below.
豊豊鼻笈友
第２リン酸カルシウム・２水和物 ５０％グリセ
リン ２０
カルボキシメチルセルロースナトリウム １ソジウム
ラウリルサルフエート １サツカリンナトリ
ウム ０．１Ω−メントール
０．５カルボン ０
．５
グルコン酸銅 ０．１計
１００．０％皿−嘉
非常に収れん性あり ：＋３
収れん性あり ：＋２
やや収れん性あり ：＋１
収れん性なし 二 〇
第 １ 表
〔実験例２〕
下記処方のマウスウォッシュを調製し、１ｏ名のパネラ
−により洗口した後の収れん性を実験例１と同様に評価
した。結果を第２表に示す。Toyohana Yoyu dicalcium phosphate dihydrate 50% glycerin 20 Sodium carboxymethyl cellulose 1 Sodium lauryl sulfate 1 Sodium saccharin 0.1Ω-menthol
0.5 carvone 0
．． 5 Copper gluconate 0.1 total
100.0% plate - Very astringent: +3 Astringent: +2 Slightly astringent: +1 No astringent The astringency after mouth rinsing with a panelist was evaluated in the same manner as in Experimental Example 1. The results are shown in Table 2.
マウスウォッシュ処方
エタノール ２０％
グリセリン １゜
ポリオキシエチレン硬化ヒマシ油 １サツカリ
ンナトリウム ０．０５ペパーミン
ト油 ０．３グルコン酸銅
０．０５計
１００．０％第 ２ 表
以下に実施例を挙げて本発明を具体的に説明するが、本
発明は下記実施例に制限されるものではない。Mouthwash formula ethanol 20% glycerin 1° polyoxyethylene hydrogenated castor oil 1 saccharin sodium 0.05 peppermint oil 0.3 copper gluconate
0.05 total
100.0% The present invention will be specifically explained with reference to Examples below in Table 2, but the present invention is not limited to the following Examples.
なお、以下の例において％はいずれも重量％である。In addition, in the following examples, all percentages are percentages by weight.
〔実施例１〕 練歯磨
リン酸処理水酸化アルミニウム ４５％カルボキ
シメチルセルロースナトリウム ０．５カラギーナン
０．５プロピレンゲリコール
３ソルビツト（６０％）
１０グリセリン（８５％）１５
ソジウムラウリルサルフェート １サツカリン
ナトリウム ０．１グルコン酸銅
０．１０−レルオレオレジン
０．００１オレンジオイル
０．０２ペパーミント油
０・５スペアミント油
０．４ノ
水 残
計 １００．０％
〔実施例２〕 液状歯磨
グリセリン ３０％
カラギーナン ２カツプリン
グシユガー ３サツカリンナトリウム
０．１ソジウムラウリルサルフエー
ト ｌクエン酸銅 ０．
１アニスオレオレジン ０．０５Ω
−メントール ０．３カルボン
０．２
水 残
計 １００．０％
〔実施例３〕 洗口剤
エタノール １５％
グリセリン １゜
サッカリンナトリウム ０．０２スペア
ミントオイル ０．４ベルガモツトオ
イル ０．０１ナツメグオレオレジン
０．００１グルコン酸銅
０．０２水
残計 １００．０％
〔実施例４〕 トローチ
アラビアゴム ６％ブドウ
糖 ４０
イソマルトース ３５ゼラチン
３
デキストラナーゼ ０．１グルコ
ン酸銅 ０．ｏルモンオイ
ル ０．１ピメントオレオ
レジン ０．００１Ω−メントール
０．１計
１００，０％
〔実施例５〕 うがい用錠剤
炭酸水素ナトリウム ５０％第２リン
酸ナトリウム １゜ポリエチレングリコ
ール ５クエン酸 ２゜
グルコン酸銅 ０．１アネ
トール ０・１ペパーミント油
０．４出願人 ラ イ オ ン
株式会社
代理人 弁理士 小 島 隆 司[Example 1] Toothpaste Phosphated Aluminum Hydroxide 45% Sodium Carboxymethyl Cellulose 0.5 Carrageenan
0.5 Propylene Gelicol 3 Sorbit (60%)
10 Glycerin (85%) 15 Sodium lauryl sulfate 1 Sodium saccharin 0.1 Copper gluconate
0.10-reloleoresin 0.001 orange oil
0.02 peppermint oil
0.5 spearmint oil
0.4 water Balance 100.0% [Example 2] Liquid toothpaste glycerin 30% Carrageenan 2 Copper juice 3 Sodium saccharin 0.1 Sodium lauryl sulfate 1 Copper citrate 0.
1 Anise oleoresin 0.05Ω
- Menthol 0.3 Carvone 0.2 Water Total balance 100.0% [Example 3] Mouthwash ethanol 15% Glycerin 1° Sodium saccharin 0.02 Spearmint oil 0.4 Bergamot oil 0.01 Nutmeg oleoresin 0. 001 Copper gluconate
0.02 water
Remaining total 100.0% [Example 4] Lozenge gum arabic 6% glucose 40 isomaltose 35 gelatin 3 dextranase 0.1 copper gluconate 0. o Lumon Oil 0.1 Pimento Oleoresin 0.001Ω-Menthol
0.1 total
100.0% [Example 5] Gargle tablet sodium bicarbonate 50% dibasic sodium phosphate 1° polyethylene glycol 5 citric acid 2° copper gluconate 0.1 anethole 0.1 peppermint oil
0.4 Applicant Lion Co., Ltd. Agent Patent Attorney Takashi Kojima
Claims (1)
酸銅及びそのアルカリ金属塩から選ばれる１種又は２種
以上の銅化合物と、カルダモンオレオレジン、ローレル
オレオレジン、ナツメグオレオレジン、ピメントオレオ
レジン、フェンネルオレオレジン、アニスオレオレジン
、ベルガモットオイル、アネトール、オレンジオイル、
レモンオイル、ライムオイルから選ばれる１種又は２種
以上の成分とを併用してなることを特徴とする口腔用組
成物。1. One or more copper compounds selected from copper gluconate and its alkali metal salts and copper citrate and its alkali metal salts, and cardamom oleoresin, laurel oleoresin, nutmeg oleoresin, pimento oleoresin, and fennel. Oleoresin, anise oleoresin, bergamot oil, anethole, orange oil,
An oral composition characterized by containing one or more components selected from lemon oil and lime oil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62313261A JP2580648B2 (en) | 1987-12-11 | 1987-12-11 | Oral composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62313261A JP2580648B2 (en) | 1987-12-11 | 1987-12-11 | Oral composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01153622A true JPH01153622A (en) | 1989-06-15 |
| JP2580648B2 JP2580648B2 (en) | 1997-02-12 |
Family
ID=18039077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62313261A Expired - Fee Related JP2580648B2 (en) | 1987-12-11 | 1987-12-11 | Oral composition |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2580648B2 (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006306846A (en) * | 2005-03-28 | 2006-11-09 | Taisho Pharmaceut Co Ltd | Copper compound-incorporated composition |
| JP2012153617A (en) * | 2011-01-24 | 2012-08-16 | Kao Corp | Cold sense enhancing agent |
| WO2014010657A1 (en) * | 2012-07-12 | 2014-01-16 | 花王株式会社 | Processed nutmeg product and method for producing same |
| WO2016136719A1 (en) * | 2015-02-26 | 2016-09-01 | ライオン株式会社 | Toothpaste composition |
| KR20210013686A (en) | 2018-05-29 | 2021-02-05 | 라이온 가부시키가이샤 | Oral composition |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56169619A (en) * | 1980-04-29 | 1981-12-26 | Blendax Werke Schneider Co | Tooth paste composition |
| JPS56169620A (en) * | 1980-04-29 | 1981-12-26 | Blendax Werke Schneider Co | Tooth paste composition |
| JPS61143317A (en) * | 1984-12-15 | 1986-07-01 | Sunstar Inc | Antimicrobial agent composition |
| JPS62142109A (en) * | 1985-12-14 | 1987-06-25 | Lotte Co Ltd | Composition for removing foul breath and method therefor |
| JPS62164614A (en) * | 1986-01-07 | 1987-07-21 | ブレンダツクス−ヴエルケ エル シユナイダ− ゲゼルシヤフト ミツト ベシユレンクテル ハフツンク ウント コンパニ− | Oral sanitary composition |
| JPS62198611A (en) * | 1986-02-27 | 1987-09-02 | Lion Corp | Composition for oral cavity application |
-
1987
- 1987-12-11 JP JP62313261A patent/JP2580648B2/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56169619A (en) * | 1980-04-29 | 1981-12-26 | Blendax Werke Schneider Co | Tooth paste composition |
| JPS56169620A (en) * | 1980-04-29 | 1981-12-26 | Blendax Werke Schneider Co | Tooth paste composition |
| JPS61143317A (en) * | 1984-12-15 | 1986-07-01 | Sunstar Inc | Antimicrobial agent composition |
| JPS62142109A (en) * | 1985-12-14 | 1987-06-25 | Lotte Co Ltd | Composition for removing foul breath and method therefor |
| JPS62164614A (en) * | 1986-01-07 | 1987-07-21 | ブレンダツクス−ヴエルケ エル シユナイダ− ゲゼルシヤフト ミツト ベシユレンクテル ハフツンク ウント コンパニ− | Oral sanitary composition |
| JPS62198611A (en) * | 1986-02-27 | 1987-09-02 | Lion Corp | Composition for oral cavity application |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006306846A (en) * | 2005-03-28 | 2006-11-09 | Taisho Pharmaceut Co Ltd | Copper compound-incorporated composition |
| JP2012153617A (en) * | 2011-01-24 | 2012-08-16 | Kao Corp | Cold sense enhancing agent |
| WO2014010657A1 (en) * | 2012-07-12 | 2014-01-16 | 花王株式会社 | Processed nutmeg product and method for producing same |
| CN104508070A (en) * | 2012-07-12 | 2015-04-08 | 花王株式会社 | Processed nutmeg product and method for producing same |
| US9918930B2 (en) | 2012-07-12 | 2018-03-20 | Kao Corporation | Processed nutmeg product and method for producing same |
| WO2016136719A1 (en) * | 2015-02-26 | 2016-09-01 | ライオン株式会社 | Toothpaste composition |
| CN107249547A (en) * | 2015-02-26 | 2017-10-13 | 狮王株式会社 | Dentrifice composition |
| KR20170122743A (en) | 2015-02-26 | 2017-11-06 | 라이온 가부시키가이샤 | Toothpaste composition |
| JPWO2016136719A1 (en) * | 2015-02-26 | 2017-12-07 | ライオン株式会社 | Dentifrice composition |
| KR20210013686A (en) | 2018-05-29 | 2021-02-05 | 라이온 가부시키가이샤 | Oral composition |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2580648B2 (en) | 1997-02-12 |
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