JP7803493B2 - 白血球濃縮分離デバイス、血液採取容器及び白血球の分離方法 - Google Patents

白血球濃縮分離デバイス、血液採取容器及び白血球の分離方法

Info

Publication number
JP7803493B2
JP7803493B2 JP2022507279A JP2022507279A JP7803493B2 JP 7803493 B2 JP7803493 B2 JP 7803493B2 JP 2022507279 A JP2022507279 A JP 2022507279A JP 2022507279 A JP2022507279 A JP 2022507279A JP 7803493 B2 JP7803493 B2 JP 7803493B2
Authority
JP
Japan
Prior art keywords
blood
collection container
blood collection
container body
blood cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022507279A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2021182575A1 (https=
Inventor
邦哉 駒井
浩信 五十川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sekisui Medical Co Ltd
Original Assignee
Sekisui Medical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sekisui Medical Co Ltd filed Critical Sekisui Medical Co Ltd
Publication of JPWO2021182575A1 publication Critical patent/JPWO2021182575A1/ja
Application granted granted Critical
Publication of JP7803493B2 publication Critical patent/JP7803493B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B01L3/50215—Test tubes specially adapted for centrifugation purposes using a float to separate phases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0631—Purification arrangements, e.g. solid phase extraction [SPE]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2022507279A 2020-03-11 2021-03-11 白血球濃縮分離デバイス、血液採取容器及び白血球の分離方法 Active JP7803493B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020042080 2020-03-11
JP2020042080 2020-03-11
PCT/JP2021/009804 WO2021182575A1 (ja) 2020-03-11 2021-03-11 白血球濃縮分離デバイス、血液採取容器及び白血球の分離方法

Publications (2)

Publication Number Publication Date
JPWO2021182575A1 JPWO2021182575A1 (https=) 2021-09-16
JP7803493B2 true JP7803493B2 (ja) 2026-01-21

Family

ID=77671614

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022507279A Active JP7803493B2 (ja) 2020-03-11 2021-03-11 白血球濃縮分離デバイス、血液採取容器及び白血球の分離方法

Country Status (7)

Country Link
US (1) US20230090675A1 (https=)
EP (1) EP4119943A4 (https=)
JP (1) JP7803493B2 (https=)
KR (1) KR20220151158A (https=)
CN (1) CN115280145A (https=)
CA (1) CA3170079A1 (https=)
WO (1) WO2021182575A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2024004522A (es) * 2021-10-15 2024-05-08 Becton Dickinson Co Mezcla con aditivos para la recogida de muestras de sangre.
CN116429734A (zh) * 2022-01-04 2023-07-14 南京医科大学 一种分离人外周血白细胞并检测活性氧的方法
KR20240168912A (ko) * 2022-03-25 2024-12-02 세키스이 메디칼 가부시키가이샤 순환 종양 세포 분리 키트, 순환 종양 세포 분리 용기 및 순환 종양 세포의 분리 방법
JP7586593B2 (ja) * 2022-09-29 2024-11-19 積水メディカル株式会社 血液保存用組成物及び血液採取容器
WO2024204675A1 (ja) * 2023-03-29 2024-10-03 積水メディカル株式会社 血液採取容器及び血漿の分離方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004344874A (ja) 2002-11-19 2004-12-09 Sekisui Chem Co Ltd 血漿もしくは血清分離膜、及び血漿もしくは血清分離膜を用いたフィルタ装置
JP2017523385A (ja) 2014-04-16 2017-08-17 ゼネラル・エレクトリック・カンパニイ ガンマ線照射安定化デキストラン溶液及び使用方法
WO2019131613A1 (ja) 2017-12-27 2019-07-04 積水メディカル株式会社 血清または血漿分離用組成物、血液採取容器、及び血清または血漿の分離方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54238Y2 (https=) * 1973-02-12 1979-01-08
JPS5854130B2 (ja) * 1978-03-17 1983-12-02 旭化成株式会社 白血球分離法
JPS603367B2 (ja) * 1979-10-09 1985-01-28 旭化成株式会社 白血球分離法および白血球分離材
JPS5737259A (en) * 1980-08-14 1982-03-01 Sherwood Medical Ind Inc Covering of stopper for anticoagulation
JPS5754860A (en) * 1980-09-17 1982-04-01 Fuerante Antonio Blood density separation
US4487700A (en) * 1983-02-18 1984-12-11 Technicon Instruments Corporation Method and apparatus for separating lymphocytes from anticoagulated blood
US4751001A (en) * 1984-09-24 1988-06-14 Becton Dickinson And Company Blood partitioning apparatus
US4640785A (en) * 1984-12-24 1987-02-03 Becton Dickinson And Company Separation of lymphocytes and monocytes from blood samples
US5397479A (en) * 1993-04-26 1995-03-14 International Remote Imaging Systems, Inc. Composition and method for enrichment of white blood cells from whole human blood
US5702884A (en) * 1996-03-12 1997-12-30 Johnson & Johnson Clinical Diagnostics, Inc. Whole blood sample preparation for polymerase chain reaction using ammonium chloride and a carboxylic acid or metal carboxylate for selective red blood cell lysis
AU4101697A (en) * 1996-11-22 1998-05-28 Robert A. Levine Process for enhancing the aggregation and/or agglutination of erythrocytes prior to centrifugation
JP4385084B2 (ja) * 2002-03-26 2009-12-16 川澄化学工業株式会社 血液成分の分離方法及び血液成分の分離装置
US7927810B2 (en) * 2002-11-19 2011-04-19 Katsuya Togawa Plasma or serum separation membrane and filter apparatus including the plasma or serum separation membrane
ES2763364T3 (es) 2009-05-15 2020-05-28 Becton Dickinson Co Dispositivo de separación de fase de densidad
KR20140034200A (ko) * 2011-04-29 2014-03-19 세븐쓰 센스 바이오시스템즈, 인크. 혈액 스폿들 또는 다른 신체 유체들을 수집 및/또는 조작하기 위한 시스템들 및 방법들
US9095798B2 (en) * 2011-08-19 2015-08-04 Microaire Surgical Instruments, Llc Centrifuge separation method and apparatus using a medium density fluid
EP2848935A4 (en) * 2012-05-10 2015-12-09 Konica Minolta Inc PROCESS FOR REMOVING RED BLOOD BODIES AND CENTRIFUGAL TUBES FOR BLOOD TREATMENT
CN106461635B (zh) * 2014-06-12 2019-12-03 立佳有限公司 由加入血浆分离胶凝剂的血液稀释保存容器进行的稀释血浆分离法
US10111610B2 (en) * 2014-11-04 2018-10-30 Wainamics, Inc. Microscale plasma separator
WO2016178931A1 (en) * 2015-05-01 2016-11-10 Mesotex, Inc. Process for separating nucleated cells from non-nucleated red blood cells
US11536635B2 (en) * 2015-06-16 2022-12-27 Tascom Co., Ltd. Biological material, measuring instrument
US10859563B2 (en) * 2015-12-01 2020-12-08 General Electric Company Erythrocyte aggregation and leukocyte isolation
JP2017129429A (ja) * 2016-01-19 2017-07-27 稲田　捷也 多白血球血漿の調整方法
JP6889535B2 (ja) * 2016-10-05 2021-06-18 デンカ株式会社 赤血球の凝集方法及び分離方法並びに赤血球凝集用試薬
US11448641B2 (en) * 2017-11-28 2022-09-20 Canon Virginia, Inc. Methods and devices for separation of blood components

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004344874A (ja) 2002-11-19 2004-12-09 Sekisui Chem Co Ltd 血漿もしくは血清分離膜、及び血漿もしくは血清分離膜を用いたフィルタ装置
JP2017523385A (ja) 2014-04-16 2017-08-17 ゼネラル・エレクトリック・カンパニイ ガンマ線照射安定化デキストラン溶液及び使用方法
WO2019131613A1 (ja) 2017-12-27 2019-07-04 積水メディカル株式会社 血清または血漿分離用組成物、血液採取容器、及び血清または血漿の分離方法

Also Published As

Publication number Publication date
EP4119943A4 (en) 2024-04-10
JPWO2021182575A1 (https=) 2021-09-16
US20230090675A1 (en) 2023-03-23
CN115280145A (zh) 2022-11-01
KR20220151158A (ko) 2022-11-14
EP4119943A1 (en) 2023-01-18
WO2021182575A1 (ja) 2021-09-16
CA3170079A1 (en) 2021-09-16

Similar Documents

Publication Publication Date Title
JP7803493B2 (ja) 白血球濃縮分離デバイス、血液採取容器及び白血球の分離方法
JP6901194B1 (ja) 血液採取容器及び血漿の分離方法
US11719689B2 (en) Composition for separating blood serum or blood plasma, blood collection container, and method for separating blood serum or blood plasma
JP2023110819A (ja) 血液採取容器、血漿の分離方法、細胞外遊離核酸の分離方法及び細胞外小胞の分離方法
JP7601359B2 (ja) 血液採取容器、血漿の分離方法、細胞外遊離核酸の分離方法及び細胞外小胞の分離方法
US20250073703A1 (en) Blood collection container, method for separating plasma, method for separating extracellular free nucleic acid, and method for separating extracellular vesicle
JP7513343B2 (ja) 単核球含有血漿分離用組成物及び血液採取容器
JP7355473B1 (ja) 循環腫瘍細胞分離キット、循環腫瘍細胞分離容器及び循環腫瘍細胞の分離方法
JP7768638B1 (ja) 血液採取容器、血漿の分離方法、細胞外遊離核酸の分離方法及び細胞外小胞の分離方法
JP7609510B1 (ja) 血液採取容器及び単核球の分離方法
CA3157473C (en) Blood collection container and plasma separation method
JP7779617B1 (ja) 血液採取容器及び血漿の分離方法
US20250331750A1 (en) Separating gel for blood collection tubes
WO2026054038A1 (ja) 血球分離用水溶液、血液採取容器及び単核球の分離方法
WO2024204675A1 (ja) 血液採取容器及び血漿の分離方法

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20230530

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20230623

A625 Written request for application examination (by other person)

Free format text: JAPANESE INTERMEDIATE CODE: A625

Effective date: 20231201

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20241224

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250128

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250430

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20250819

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250904

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20251209

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20251224

R150 Certificate of patent or registration of utility model

Ref document number: 7803493

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150