JP7786383B2 - 生物体操作方法および生物体操作装置 - Google Patents

生物体操作方法および生物体操作装置

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Publication number
JP7786383B2
JP7786383B2 JP2022552087A JP2022552087A JP7786383B2 JP 7786383 B2 JP7786383 B2 JP 7786383B2 JP 2022552087 A JP2022552087 A JP 2022552087A JP 2022552087 A JP2022552087 A JP 2022552087A JP 7786383 B2 JP7786383 B2 JP 7786383B2
Authority
JP
Japan
Prior art keywords
bubble
nozzle
unit
gas
flow path
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022552087A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2022065459A5 (https=
JPWO2022065459A1 (https=
Inventor
真樹 森山
直也 石澤
遼 小林
太一 中村
修平 田中
世莉 林
牧子 田窪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nikon Corp
Original Assignee
Nikon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nikon Corp filed Critical Nikon Corp
Publication of JPWO2022065459A1 publication Critical patent/JPWO2022065459A1/ja
Publication of JPWO2022065459A5 publication Critical patent/JPWO2022065459A5/ja
Priority to JP2025228369A priority Critical patent/JP2026041874A/ja
Application granted granted Critical
Publication of JP7786383B2 publication Critical patent/JP7786383B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0469—Buoyancy
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2022552087A 2020-09-24 2021-09-24 生物体操作方法および生物体操作装置 Active JP7786383B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025228369A JP2026041874A (ja) 2020-09-24 2025-12-04 生物体操作方法および生物体操作装置

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020160261 2020-09-24
JP2020160261 2020-09-24
PCT/JP2021/035201 WO2022065459A1 (ja) 2020-09-24 2021-09-24 生物体操作方法および生物体操作装置

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025228369A Division JP2026041874A (ja) 2020-09-24 2025-12-04 生物体操作方法および生物体操作装置

Publications (3)

Publication Number Publication Date
JPWO2022065459A1 JPWO2022065459A1 (https=) 2022-03-31
JPWO2022065459A5 JPWO2022065459A5 (https=) 2024-07-05
JP7786383B2 true JP7786383B2 (ja) 2025-12-16

Family

ID=80846677

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022552087A Active JP7786383B2 (ja) 2020-09-24 2021-09-24 生物体操作方法および生物体操作装置
JP2025228369A Pending JP2026041874A (ja) 2020-09-24 2025-12-04 生物体操作方法および生物体操作装置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025228369A Pending JP2026041874A (ja) 2020-09-24 2025-12-04 生物体操作方法および生物体操作装置

Country Status (5)

Country Link
US (1) US20230347346A1 (https=)
EP (1) EP4223864A1 (https=)
JP (2) JP7786383B2 (https=)
CN (1) CN116670264A (https=)
WO (1) WO2022065459A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538287A (ja) 2002-08-15 2005-12-15 エムイーエムエスフロー・アンパルトセルスカブ マイクロ液体処理装置とその使用方法
WO2015098919A1 (ja) 2013-12-27 2015-07-02 積水化学工業株式会社 細胞の剥離方法、細胞支持用基材、並びに、細胞の培養方法
JP7331921B2 (ja) 2019-03-25 2023-08-23 株式会社ニコン 細胞操作システム及び細胞操作方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0715440Y2 (ja) * 1989-09-21 1995-04-12 株式会社ツムラ 反応容器
JP3326881B2 (ja) 1993-06-25 2002-09-24 株式会社ニコン 走査型光学顕微鏡
JP3814869B2 (ja) 1996-05-14 2006-08-30 株式会社ニコン 共焦点レーザ走査顕微鏡
US6694197B1 (en) * 2000-04-24 2004-02-17 Pharmacopeia Drug Discovery Inc. Single channel reformatter
US8920751B2 (en) * 2011-07-08 2014-12-30 Life Technologies Corporation Automated enrichment for nucleic acid sequencing
JP6676300B2 (ja) * 2015-07-28 2020-04-08 ヤマハ発動機株式会社 対象物移動方法及び装置
JP6787274B2 (ja) 2017-08-09 2020-11-18 横河電機株式会社 細胞吸引支援システム

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538287A (ja) 2002-08-15 2005-12-15 エムイーエムエスフロー・アンパルトセルスカブ マイクロ液体処理装置とその使用方法
WO2015098919A1 (ja) 2013-12-27 2015-07-02 積水化学工業株式会社 細胞の剥離方法、細胞支持用基材、並びに、細胞の培養方法
JP7331921B2 (ja) 2019-03-25 2023-08-23 株式会社ニコン 細胞操作システム及び細胞操作方法
JP7643495B2 (ja) 2019-03-25 2025-03-11 株式会社ニコン 生物体操作装置及び生物体操作方法
JP2025074131A (ja) 2019-03-25 2025-05-13 株式会社ニコン 細胞操作方法

Also Published As

Publication number Publication date
JP2026041874A (ja) 2026-03-10
CN116670264A (zh) 2023-08-29
EP4223864A1 (en) 2023-08-09
US20230347346A1 (en) 2023-11-02
WO2022065459A1 (ja) 2022-03-31
JPWO2022065459A1 (https=) 2022-03-31

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