JP7569389B2 - 液体クロマトグラフの制御方法および液体クロマトグラフ - Google Patents

液体クロマトグラフの制御方法および液体クロマトグラフ Download PDF

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Publication number
JP7569389B2
JP7569389B2 JP2022572089A JP2022572089A JP7569389B2 JP 7569389 B2 JP7569389 B2 JP 7569389B2 JP 2022572089 A JP2022572089 A JP 2022572089A JP 2022572089 A JP2022572089 A JP 2022572089A JP 7569389 B2 JP7569389 B2 JP 7569389B2
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Prior art keywords
pressure
flow path
sample injection
analysis flow
pump
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JP2022572089A
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Japanese (ja)
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JPWO2022138136A5 (https=
JPWO2022138136A1 (https=
Inventor
伸也 伊藤
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Hitachi High Tech Corp
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Hitachi High Tech Corp
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/163—Pressure or speed conditioning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/326—Control of physical parameters of the fluid carrier of pressure or speed pumps
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8658—Optimising operation parameters

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2022572089A 2020-12-24 2021-12-07 液体クロマトグラフの制御方法および液体クロマトグラフ Active JP7569389B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020215049 2020-12-24
JP2020215049 2020-12-24
PCT/JP2021/044920 WO2022138136A1 (ja) 2020-12-24 2021-12-07 液体クロマトグラフの制御方法および液体クロマトグラフ

Publications (3)

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JPWO2022138136A1 JPWO2022138136A1 (https=) 2022-06-30
JPWO2022138136A5 JPWO2022138136A5 (https=) 2023-07-24
JP7569389B2 true JP7569389B2 (ja) 2024-10-17

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JP2022572089A Active JP7569389B2 (ja) 2020-12-24 2021-12-07 液体クロマトグラフの制御方法および液体クロマトグラフ

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Country Link
US (1) US12360087B2 (https=)
EP (1) EP4270000A4 (https=)
JP (1) JP7569389B2 (https=)
CN (1) CN116569035A (https=)
WO (1) WO2022138136A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026070108A1 (ja) * 2024-09-27 2026-04-02 株式会社日立ハイテク 自動分析装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020094817A (ja) 2018-12-10 2020-06-18 株式会社日立ハイテク 液体クロマトグラフ質量分析装置
JP2020524282A (ja) 2017-06-19 2020-08-13 ウオーターズ・テクノロジーズ・コーポレイシヨン 科学機器システムにおける平衡化及び安定性を判定する技術

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4422942A (en) * 1981-09-09 1983-12-27 Isco, Inc. Method for liquid chromatography
JPH07103151B2 (ja) * 1990-06-28 1995-11-08 日本碍子株式会社 アフィニティクロマトグラフィーによる抗体の精製方法
CN110075568A (zh) 2012-08-24 2019-08-02 通用电气健康护理生物科学股份公司 控制液相色谱系统的系统和方法
DE102017126893A1 (de) 2017-11-15 2019-05-16 Agilent Technologies, Inc. - A Delaware Corporation - Analysemethode mit Erwartungskorridor als Bewertungsgrundlage für Analyseergebnis
JP7186113B2 (ja) * 2019-03-01 2022-12-08 株式会社日立ハイテク 送液ポンプ、液体クロマトグラフ装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020524282A (ja) 2017-06-19 2020-08-13 ウオーターズ・テクノロジーズ・コーポレイシヨン 科学機器システムにおける平衡化及び安定性を判定する技術
JP2020094817A (ja) 2018-12-10 2020-06-18 株式会社日立ハイテク 液体クロマトグラフ質量分析装置

Also Published As

Publication number Publication date
EP4270000A4 (en) 2024-11-27
US12360087B2 (en) 2025-07-15
EP4270000A1 (en) 2023-11-01
CN116569035A (zh) 2023-08-08
US20240019407A1 (en) 2024-01-18
WO2022138136A1 (ja) 2022-06-30
JPWO2022138136A1 (https=) 2022-06-30

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