JP7522726B2 - ピロールイミダゾール（ポリ）アミドの製造方法 - Google Patents

ピロールイミダゾール（ポリ）アミドの製造方法 Download PDF

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JP7522726B2
JP7522726B2 JP2021509028A JP2021509028A JP7522726B2 JP 7522726 B2 JP7522726 B2 JP 7522726B2 JP 2021509028 A JP2021509028 A JP 2021509028A JP 2021509028 A JP2021509028 A JP 2021509028A JP 7522726 B2 JP7522726 B2 JP 7522726B2
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JPWO2020195889A1 (https=
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貴彦 村田
昇平 山本
章 西山
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Kaneka Corp
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Kaneka Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • C07D207/408—Radicals containing only hydrogen and carbon atoms attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
JP2021509028A 2019-03-28 2020-03-12 ピロールイミダゾール（ポリ）アミドの製造方法 Active JP7522726B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019063936 2019-03-28
JP2019063936 2019-03-28
PCT/JP2020/010792 WO2020195889A1 (ja) 2019-03-28 2020-03-12 ピロールイミダゾール（ポリ）アミドの製造方法

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JPWO2020195889A1 JPWO2020195889A1 (https=) 2020-10-01
JP7522726B2 true JP7522726B2 (ja) 2024-07-25

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JP2021509028A Active JP7522726B2 (ja) 2019-03-28 2020-03-12 ピロールイミダゾール（ポリ）アミドの製造方法

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US (1) US12454526B2 (https=)
JP (1) JP7522726B2 (https=)
WO (1) WO2020195889A1 (https=)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000503324A (ja) 1996-02-26 2000-03-21 カリフォルニア インスティテュート オブ テクノロジー 固体支持体上でのポリピロール及びポリイミダゾールカルボキサミドの合成方法
JP2012510512A (ja) 2008-12-03 2012-05-10 マサチューセッツ インスティテュート オブ テクノロジー 記憶を推進するためのｈｄａｃ２の阻害

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555692B1 (en) 1996-02-26 2003-04-29 California Institute Of Technology Preparation and use of bifunctional molecules having DNA sequence binding specificity
AU6255298A (en) 1996-02-26 1998-09-09 California Institute Of Technology Design, synthesis and use of specific polyamide dna-binding ligands
US6143901A (en) 1996-07-31 2000-11-07 Genesoft, Inc. Complex formation between dsDNA and pyrrole imidazole polyamides
WO1998037066A1 (en) 1996-02-26 1998-08-27 California Institute Of Technology Improved polyamides for binding in the minor groove of double stranded dna
US6506906B1 (en) 1996-02-26 2003-01-14 California Institute Of Technology Preparation and use of bifunctional molecules having DNA sequence binding specificity
US6635417B1 (en) 1996-07-31 2003-10-21 California Institute Of Technology Complex formation between DSDNA and oligomer of cyclic heterocycles
CN1260006A (zh) 1996-02-26 2000-07-12 加利福尼亚州技术学院 双链dna和杂环低聚物之间复合物的形成
EP1023288A1 (en) 1996-02-26 2000-08-02 California Institute Of Technology Stereochemical control of the dna binding affinity, sequence specificity, and orientation-preference of chiral hairpin polyamides in the minor groove
US5998140A (en) 1996-07-31 1999-12-07 The Scripps Research Institute Complex formation between dsDNA and oligomer of cyclic heterocycles
US6660255B1 (en) 1996-08-01 2003-12-09 California Institute Of Technology Inhibition of gene transcription by polyamide DNA-binding ligands
AU766025B2 (en) 1997-02-10 2003-10-09 Cti, Inc. Segmented scintillation detector for photon interaction coordinates

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000503324A (ja) 1996-02-26 2000-03-21 カリフォルニア インスティテュート オブ テクノロジー 固体支持体上でのポリピロール及びポリイミダゾールカルボキサミドの合成方法
JP2012510512A (ja) 2008-12-03 2012-05-10 マサチューセッツ インスティテュート オブ テクノロジー 記憶を推進するためのｈｄａｃ２の阻害

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
NNADI, C. I. et al.，Journal of Chemical Information and Modeling，2018年，Vol. 58，pp. 464-471
TRIPATHI, S. et al.，Bioorganic & Medicinal Chemistry Letters，2005年，Vol. 15，pp. 5045-5048
WETZLER, M. et al.，Organic Letters，2010年，Vol. 12，pp. 3488-3490
有機合成用縮合剤 第２版，富士フイルム 和光純薬株式会社，2018年，第1-16頁

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JPWO2020195889A1 (https=) 2020-10-01
WO2020195889A1 (ja) 2020-10-01
US12454526B2 (en) 2025-10-28
US20220153727A1 (en) 2022-05-19

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