JP7515940B2 - 被検出物質の検出方法、検出キットおよび検出システム、ならびに、検出キットの製造方法 - Google Patents

被検出物質の検出方法、検出キットおよび検出システム、ならびに、検出キットの製造方法 Download PDF

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JP7515940B2
JP7515940B2 JP2023518698A JP2023518698A JP7515940B2 JP 7515940 B2 JP7515940 B2 JP 7515940B2 JP 2023518698 A JP2023518698 A JP 2023518698A JP 2023518698 A JP2023518698 A JP 2023518698A JP 7515940 B2 JP7515940 B2 JP 7515940B2
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志保 床波
琢也 飯田
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University Public Corporation Osaka
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50851—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G01N15/075—Investigating concentration of particle suspensions by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G01N15/0656—Investigating concentration of particle suspensions using electric, e.g. electrostatic methods or magnetic methods
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B01L2300/1872—Infrared light
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0442—Moving fluids with specific forces or mechanical means specific forces thermal energy, e.g. vaporisation, bubble jet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0442—Moving fluids with specific forces or mechanical means specific forces thermal energy, e.g. vaporisation, bubble jet
    • B01L2400/0445—Natural or forced convection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0038—Investigating nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6421—Measuring at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
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    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles

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  • Immunology (AREA)
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  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
JP2023518698A 2021-05-07 2022-05-02 被検出物質の検出方法、検出キットおよび検出システム、ならびに、検出キットの製造方法 Active JP7515940B2 (ja)

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PCT/JP2022/019532 WO2022234849A1 (ja) 2021-05-07 2022-05-02 被検出物質の検出方法、検出キットおよび検出システム、ならびに、検出キットの製造方法

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Citations (10)

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JP2005283556A (ja) 2004-03-05 2005-10-13 Canon Inc 標的物質認識素子、検出方法及び装置
WO2012077756A1 (ja) 2010-12-08 2012-06-14 公立大学法人大阪府立大学 金属ナノ粒子集積構造体を利用した被検出物質の検出装置および方法
US20140293731A1 (en) 2013-03-27 2014-10-02 Nanotemper Technologies Gmbh Method and apparatus for contactless mixing of liquids
WO2014192937A1 (ja) 2013-05-30 2014-12-04 公立大学法人大阪府立大学 被検出物質の検出装置および方法
US20150316480A1 (en) 2014-05-05 2015-11-05 Nanotemper Technologies Gmbh Thermophoresis measurements in nanoliterdroplets
WO2017090087A1 (ja) 2015-11-24 2017-06-01 株式会社日立ハイテクノロジーズ 生体試料分析装置および生体試料分析方法
WO2018159706A1 (ja) 2017-02-28 2018-09-07 公立大学法人大阪府立大学 微小物体の集積装置、および、それに用いられる集積容器ならびに微小物体の集積方法
WO2018207937A1 (ja) 2017-05-12 2018-11-15 公立大学法人大阪府立大学 インピーダンス測定システムおよびインピーダンス測定方法ならびに被検出物質の検出システム
JP2018194550A (ja) 2017-05-12 2018-12-06 公立大学法人大阪府立大学 被検出物質の検出キットおよびそれを備えた検出システム、ならびに、被検出物質の検出キットの製造方法
WO2020218347A1 (ja) 2019-04-25 2020-10-29 公立大学法人大阪 微小物体の集積方法および微小物体の集積システム

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WO2017127570A1 (en) * 2016-01-20 2017-07-27 Triv Tech, Llc Point-of-care nucleic acid amplification and detection
JP6375578B2 (ja) 2016-05-11 2018-08-22 公立大学法人大阪府立大学 微小物体の捕集装置および捕集キットならびに微小物体の捕集方法

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JP2005283556A (ja) 2004-03-05 2005-10-13 Canon Inc 標的物質認識素子、検出方法及び装置
WO2012077756A1 (ja) 2010-12-08 2012-06-14 公立大学法人大阪府立大学 金属ナノ粒子集積構造体を利用した被検出物質の検出装置および方法
US20140293731A1 (en) 2013-03-27 2014-10-02 Nanotemper Technologies Gmbh Method and apparatus for contactless mixing of liquids
WO2014192937A1 (ja) 2013-05-30 2014-12-04 公立大学法人大阪府立大学 被検出物質の検出装置および方法
US20150316480A1 (en) 2014-05-05 2015-11-05 Nanotemper Technologies Gmbh Thermophoresis measurements in nanoliterdroplets
WO2017090087A1 (ja) 2015-11-24 2017-06-01 株式会社日立ハイテクノロジーズ 生体試料分析装置および生体試料分析方法
WO2018159706A1 (ja) 2017-02-28 2018-09-07 公立大学法人大阪府立大学 微小物体の集積装置、および、それに用いられる集積容器ならびに微小物体の集積方法
WO2018207937A1 (ja) 2017-05-12 2018-11-15 公立大学法人大阪府立大学 インピーダンス測定システムおよびインピーダンス測定方法ならびに被検出物質の検出システム
JP2018194550A (ja) 2017-05-12 2018-12-06 公立大学法人大阪府立大学 被検出物質の検出キットおよびそれを備えた検出システム、ならびに、被検出物質の検出キットの製造方法
WO2020218347A1 (ja) 2019-04-25 2020-10-29 公立大学法人大阪 微小物体の集積方法および微小物体の集積システム

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Damage-free light-induced assembly of intestinal bacteria with a bubble-mimetic substrate，COMMUNICATIONS BIOLOGY，2021年03月22日，4:385，pp. 1-7, pp. S1-S10，doi: 10.1038/s42003-021-01807-w
プラズモニック・ナノボウル基板によるナノ粒子の光濃縮検出，第８２回応用物理学会秋季学術講演会講演予稿集，公益社団法人応用物理学会，2020年02月28日，12p-N107-11

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US20240241026A1 (en) 2024-07-18
JPWO2022234849A1 (https=) 2022-11-10

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