JP7494421B2 - Granule-blended effervescent tablet - Google Patents

Description

The present invention relates to effervescent tablets that contain granules with a specific particle size and bulk density and have a specific carbon dioxide generating power.

It has been common to add bath additives to bath water for the purpose of giving a fragrance or color to the bath water to make the bather feel refreshed, activating the metabolism to improve poor circulation, and obtaining a warm bath effect. For example, various forms such as powder, liquid, bath salt, and tablet have been put to practical use. These bath additives contain ingredients such as moisturizers and inorganic salts to impart a warm bath effect and a skin care effect, and also contain fragrances and opacifiers to enhance the relaxing effect when used. The scent during bathing relieves mental and physical tension and makes the mood refreshed, so many studies on scent control have been reported in the past (e.g., Patent Documents 1 to 3, etc.). In addition, in order to produce an appearance, it has been reported that the bath water is colored by adding a pigment, and that mica or titanium mica is added to make the bath water pearly (e.g., Patent Document 4, etc.), and that titanium oxide is added to make the bath water opaque to imitate a natural hot spring (e.g., Patent Document 5, etc.).
On the other hand, the ingredients added to bath additives to impart a warming effect or skin care effect are designed to dissolve easily in the bath water when added, making it difficult for bathers to visually confirm the ingredients in the bath water. As a result, bathers are only able to experience the warming effect or skin care effect of the ingredients while bathing.

JP 2008-019175 A JP 2009-167116 A JP 2004-083731 A Japanese Patent Application Laid-Open No. 08-291048 JP 2020-007241 A

The present invention aims to provide an effervescent tablet that allows bathers to feel the effects of the ingredients not only physically, but also both visually and physically by making the ingredients visible in the bathwater, by formulating bath additives that contain ingredients that are blended to provide a warm bath effect or skin care effect.

As a result of extensive research into solving the above problems, the inventors discovered that by setting the particle size and bulk density of the granules within a specific range, and further setting the carbon dioxide gas generating capacity (the amount of carbon dioxide gas generated during use divided by the dissolution time of the effervescent tablet) to a specific amount or more, the granules rise to the surface of the bath water together with the effervescence of carbon dioxide gas and diffuse widely, thereby completing the present invention.

Specifically, the present invention relates to the following items.
1. An effervescent tablet comprising granules having a particle size of 0.5 mm or more and a bulk density of 0.7 g/mL or less, and having a carbon dioxide gas generating capacity of 1.0 mL/sec or more during use.
2. The effervescent tablet according to 1., further comprising a carbonate and an organic acid.
3. The effervescent tablet according to 1. or 2., which is an effervescent tablet for use as a bath additive.

The effervescent tablet of the present invention has the effect that when it is dropped into water, etc., the granules rise to the water surface as the carbon dioxide gas generated effervesces and are dispersed widely.
In addition, when the effervescent tablet of the present invention is used as a bath additive, the granules rise to the surface of the bath water along with the effervescence of carbon dioxide gas and spread widely, allowing the bather to visually confirm the ingredients contained in the granules. In other words, the effect of the ingredients can be felt not only physically but also visually.
As a result, the effervescent tablet for bath additives of the present invention is useful in that it provides a presentation effect that allows the user to feel both physically and visually a relaxing effect in addition to a warm bath effect and a skin care effect.

The effervescent tablet and the effervescent tablet for bath additives of the present invention will be described in detail below.
<Granules>
The effervescent tablet of the present invention contains granules having a particle size of 0.5 mm or more and a bulk density of 0.7 g/mL or less.
The particle size of the granules in the present invention may be 0.5 mm or more by sieving, preferably 1.0 mm or more, and more preferably 1.4 mm or more. The particle size is preferably 4 mm or less, more preferably 3 mm or less, and even more preferably 2.5 mm or less. If the particle size is smaller than 0.5 mm, many granules will not rise to the water surface when the effervescent tablet of the present invention is put into water.
The bulk density of the granules in the present invention means what is generally called "loose bulk density", and is calculated by filling a container (100 mL) with granules "loosely" to the top without tapping, and dividing the weight of the filled granules by 100. The bulk density of the granules in the present invention may be 0.7 g/mL or less, preferably 0.5 g/mL or less, and more preferably 0.4 g/mL or less. The bulk density is preferably 0.2 g/mL or more, more preferably 0.3 g/mL or more, and even more preferably 0.4 g/mL or more.

The effervescent tablet of the present invention is preferably formulated with a component that imparts a desired effect to the granules contained therein. In particular, the effervescent tablet for bath additives of the present invention is preferably formulated with a component that imparts a warm bath effect or a skin care effect to the granules, and in particular, it is preferably formulated with herbal medicines.
Examples of herbal medicines to be blended in the granules contained in the effervescent tablet for bath additives of the present invention include chamomile, chinese laurel, camphor, fennel, chinese laurel, cinnamon, ginger, tangerine, cnidium rhizome, calamus, angelica, spruce, dokudami, chili pepper, white birch, burdock, carrot, garlic, clove, rosemary, yuzu, and thyme. These may be blended as herbal extracts, or the herbal extracts may be dried and blended. The blending amount is preferably in the range of 0.001 to 50% by weight, more preferably 0.1 to 10% by weight, based on the total weight of the granules.

The granules of the present invention can be obtained, for example, by dry granulation using various ingredients such as inorganic salts, binders and dyes in addition to ingredients such as herbal medicines, more specifically, optional ingredients that can be incorporated into the effervescent tablet of the present invention as described below.
Examples of inorganic salts that can be blended include chlorides such as sodium chloride, potassium chloride, and ammonium chloride; carbonates such as sodium sesquicarbonate, sodium carbonate, sodium hydrogen carbonate, calcium carbonate, potassium carbonate, magnesium carbonate, and heavy magnesium carbonate; sulfates such as sodium sulfate, aluminum sulfate, iron sulfate, aluminum potassium sulfate, sodium thiosulfate, calcium thiosulfate, potassium thiosulfate, and sodium hyposulfite; nitrates such as sodium nitrate, potassium nitrate, and calcium nitrate; phosphates such as sodium phosphate and calcium hydrogen phosphate; sulfides such as calcium silicate, magnesium silicate, calcium sulfide, calcium bisulfide, potassium sulfide, sodium sulfide, ammonium sulfide, barium sulfide, zinc sulfide, tin sulfide, antimony sulfide, iron sulfide, carbon disulfide, and phosphorus sulfide; hydroxides such as sodium hydroxide and calcium hydroxide; borax, boric acid, calcium oxide, potassium bromide, and potassium permanganate. Among the above inorganic salts, sodium carbonate, sodium hydrogen carbonate, and sodium sulfate are preferred.
The binder that can be added is preferably a polymer binder, and more preferably a water-soluble polymer binder. Examples of such polymer binders include cationic polymers, carboxymethylcellulose and its salts, hydroxyethylcellulose and its salts, alginic acid and its salts, polyphosphoric acid and its salts, polyacrylic acid and its salts, pyrophosphoric acid and its salts, crystalline cellulose, gum arabic, xanthan gum, guar gum, locust bean gum, gelatin, styrene polymer emulsion, dextrin, polyethylene glycol, liquid paraffin, casein, polyoxyethylene polyoxypropylene glycol, polyethylene glycol monostearate, etc., and one or more of these polymer binders can be used. The amount of the polymer binder added is preferably in the range of 1 to 80% by weight, more preferably in the range of 10 to 70% by weight, and even more preferably in the range of 20 to 60% by weight, based on the total weight of the granules.

When the effervescent tablet of the present invention is dropped into water, the granules rise to the water surface with the foaming of the carbon dioxide gas generated and spread widely. Therefore, in order to obtain a visual effect, it is preferable to blend a colorant with the granules. Examples of colorants that can be blended include legal colorants such as Blue No. 1, Blue No. 2, Red No. 102, Red No. 106, Red No. 227, Red No. 230 (1), Yellow No. 4, Yellow No. 5, Yellow No. 202 (1), Green No. 3, Green No. 201, Green No. 204, and Orange No. 205, as well as natural colorants such as chlorophyll, riboflavin, annatto, and anthocyanin.

<Carbon dioxide generation during use>
The effervescent tablet of the present invention has a carbon dioxide gas generating capacity of 1.0 mL/sec or more, calculated from the amount of carbon dioxide gas generated during use and the dissolution time of the effervescent tablet. This carbon dioxide gas generating capacity is preferably 1.5 mL/sec or more, more preferably 2.0 mL/sec or more, and even more preferably 2.5 mL/sec or more.
The carbon dioxide gas generating capacity in the present invention is calculated by the following formula.
[a formula]
Carbon dioxide generation capacity = amount of carbon dioxide generated (mL) ÷ dissolution time of effervescent tablet (seconds)
The amount of carbon dioxide gas generated (mL) and the dissolution time (seconds) of the effervescent tablet refer to values measured by the following procedure.
One 45 g effervescent tablet compressed with a tablet press is placed in a cylindrical metal wire basket (diameter 10 cm x height 10 cm) and this is immersed in 200 L of hot water at 40°C (bathtub: approximately 0.68 m x 1.1 m x height 0.46 m). A funnel is placed just above the top of the metal wire basket in the water and all of the generated gas (carbon dioxide) is collected in a measuring cylinder to measure the amount of carbon dioxide generated and the time (seconds) for the effervescent tablet to dissolve.
The amount of carbon dioxide gas generated during use is preferably 350 mL or more, and more preferably 400 mL or more.

The effervescent tablet of the present invention preferably contains a carbonate and an organic acid.
<Carbonates>
The carbonate may be any that reacts with an organic acid during use to generate carbon dioxide gas, and examples of the carbonate include sodium hydrogen carbonate, sodium carbonate, sodium sesquicarbonate, calcium carbonate, potassium carbonate, magnesium carbonate, heavy magnesium carbonate, etc., and one or more of these may be used. Among these, sodium hydrogen carbonate and sodium carbonate are preferred.
In the effervescent tablet of the present invention, the amount of carbonate is preferably in the range of 20% by weight or more and 75% by weight or less, more preferably in the range of 25% by weight or more and 70% by weight or less, and even more preferably in the range of 30% by weight or more and 65% by weight or less, based on the total weight of the effervescent tablet.

<Organic Acid>
The organic acid may be any acid that reacts with a carbonate to generate carbon dioxide gas, but taking into consideration the form of use as a bath additive, examples include one or more acids selected from fumaric acid, citric acid, malic acid, tartaric acid, succinic acid, maleic acid, phthalic acid, glutaric acid, adipic acid, benzoic acid, salicylic acid, and oxalic acid, etc. Among these, succinic acid, fumaric acid, malic acid, and citric acid are preferred.
In the effervescent tablet of the present invention, the amount of organic acid is preferably in the range of 10% by weight or more and 55% by weight or less, more preferably in the range of 15% by weight or more and 50% by weight or less, and even more preferably less than 45% by weight, based on the total weight of the effervescent tablet.

<Tableting>
The effervescent tablet of the present invention can be produced, for example, by mixing granules, carbonates, organic acids, etc., and tableting using a known tablet press. A known tablet press is a device that fills a powder mixture in a die and compresses it between a lower punch and an upper punch to form it. Tablet presses include a single-shot tablet press in which a pair of upper and lower punches move up and down in one die to compress, and a rotary tablet press in which dies are embedded at equal intervals on the periphery of a horizontally rotating turntable, and a series of operations of filling, compression, and discharge are continuously performed while the turntable rotates. Examples of known tablet presses include a single-shot tablet press manufactured by Shiga Seisakusho Co., Ltd., and a rotary tablet press manufactured by Kikusui Seisakusho Co., Ltd. In addition, tablets can be produced by single-shot tableting using a punch and die that matches the weight of the tablet to be produced and a hydraulic pump, such as those manufactured by Labonect Co., Ltd. or Riken Kiki Co., Ltd. The tableting method is not particularly limited, and the tablet can be produced by a direct powder tableting method (direct compression method) or a granule tableting method (indirect compression method). The order of mixing the components and the method of mixing can be appropriately selected.
The size of the tablet when using a tablet press is preferably 80 mm or less in diameter (length of one side in the case of a polygonal shape), more preferably 60 mm or less, and more preferably 10 mm or more, and more preferably 30 mm or more. The thickness of the tablet is preferably 20 mm or less, more preferably 17 mm or less, and more preferably 5 mm or more, more preferably 8 mm or more, and even more preferably 10 mm or more. The shape of the tablet is not particularly limited, but is selected from cylindrical, block, spherical, hemispherical, polygonal, etc., and is preferably cylindrical.

When the effervescent tablet of the present invention is used as a bath additive, in addition to the granules containing the above-mentioned ingredients such as herbal medicines, carbonates, and organic acids, one or more optional ingredients that are various ingredients known in the field of bath additives can be added as necessary. The following are examples of optional ingredients that can be added when the effervescent tablet of the present invention is used as a bath additive, but it goes without saying that the ingredients are not limited to those described here.

<Inorganic salts (excluding carbonates)>
Examples of inorganic salts include chlorides such as sodium chloride, potassium chloride, and ammonium chloride, sulfates such as sodium sulfate, aluminum sulfate, iron sulfate, aluminum potassium sulfate, sodium thiosulfate, calcium thiosulfate, potassium thiosulfate, and sodium hyposulfite, nitrates such as sodium nitrate, potassium nitrate, and calcium nitrate, phosphates such as sodium phosphate and calcium hydrogen phosphate, sulfides such as calcium silicate, magnesium silicate, calcium sulfide, calcium bisulfide, potassium sulfide, sodium sulfide, ammonium sulfide, barium sulfide, zinc sulfide, tin sulfide, antimony sulfide, iron sulfide, carbon disulfide, and phosphorus sulfide, hydroxides such as sodium hydroxide and calcium hydroxide, borax, boric acid, calcium oxide, potassium bromide, and potassium permanganate. Among the above inorganic salts, phosphates such as sodium chloride, sodium sulfate, aluminum potassium sulfate, and sodium phosphate, and calcium silicate are preferred, and in particular, when the effervescent tablet of the present invention is used as a bath additive, it is preferable to contain sodium sulfate and calcium silicate, and in particular, it is preferable to contain sodium sulfate.
When sodium sulfate is blended into the effervescent tablet of the present invention, the blending amount is preferably in the range of 10% by weight or more and 35% by weight or less based on the total weight of the effervescent tablet.

<Oily ingredients>
Examples of such oils and fats include natural oils and fats such as rice bran oil, jojoba oil, olive oil, soybean oil, etc.; hydrocarbons such as vaseline, squalane, squalene, etc.; alcohols such as stearyl alcohol, cetyl alcohol, etc.; fatty acids such as myristic acid, lauric acid, palmitic acid, etc.; synthetic oils and fats such as monoglycerides, triglycerides, etc.; silicones, etc. These can also be contained as moisturizing components.
<Polymer substances>
Examples of such polymers include cationic polymers, carboxymethylcellulose and its salts, hydroxyethylcellulose and its salts, alginic acid and its salts, polyphosphoric acid and its salts, polyacrylic acid and its salts, pyrophosphoric acid and its salts, crystalline cellulose, gum arabic, xanthan gum, guar gum, locust bean gum, gelatin, styrene polymer emulsion, dextrin, polyethylene glycol, liquid paraffin, casein, polyoxyethylene polyoxypropylene glycol, polyethylene glycol monostearate, etc. Among the above polymeric substances, when the effervescent tablet of the present invention is used as a bath additive, it is preferable to contain liquid paraffin, dextrin, and polyethylene glycol, which are also suitable as formulation aids.

<Fragrance ingredients and essential oil ingredients>
Mint, eucalyptus, lemon, verbena, citronella, cajaput, salvia, thyme, clove, rosemary, hyssop, jasmine, chamomile, neroli, mugwort, perilla, marjoram, laurel, juniper berry, nutmeg, ginger, onion, garlic, lavender, bergamot, clary sage, peppermint, basil, rose, petitgrain, cinnamon, mace, citral, citronellal, borneol, linalool, geraniol, nerol, rhodinol, orange, artemisia, camphor, menthol, cineole, eugenol, hydroxycitronellal, sandalwood, costus, labdanum, amber, musk, alpha-pinene, limonene, methyl salicylate "Perfume" contains essential oils such as chili, sophora rhizome, white atractylodes, valerian, kaempferia, magnolia, cnidium, spruce, angelica, ginger, peony, phellodendron bark, scutellaria, Chinese radish, cinnamon, carrot, poria, dokkatsu, calamus, Chinese laurel, daisy, angelica, fennel, tangerine, and chamomile, amyl nitrite, trimethylcyclohexanol, allyl sulfide, nonyl alcohol, decyl alcohol, phenylethyl alcohol, methyl carbonate, ethyl carbonate, phenylacetic acid ester, guaiacol, indole, cresol, thiophenol, p-dichlorobenzene, p-methylquinoline, isoquinoline, pyridine, abscisse oil acetic acid, and acetate. and Flavor Materials of Natural Origin, Steffen Arctander, Allured Pub. Co. (1960), "Encyclopedia of Fragrance", edited by the Japan Fragrance Association, Asakura Shoten (1989), "Flower oils and Floral Compounds in Perfumery", Danute Pajaujis Anonis, Allured Pub. Co. (1993), "Perfume and Flavor Chemicals (aroma chemicals)", Vols. I and II, Steffen Arctander, Allured Pub. Co. (1994), "Fundamentals of Fragrance and Fragrance Blending", edited by Nakajima Mototaka, Sangyo Tosho (1995), "Synthetic Fragrances: Chemistry and Product Knowledge", written by Indo Genichi, Chemical Daily Co. (1996), and "Encyclopedia of Fragrances", edited by Tanidagai Mitsukatsu, Maruzen (2005). These fragrance components and essential oil components can be used alone or in any combination of two or more types to be used as blended fragrances. Furthermore, they can be appropriately mixed with solvents, fragrance stabilizers, etc. and used as fragrance compositions.

<Herbal medicines>
The effervescent tablet of the present invention may contain herbal medicines in the portion other than the granules. The herbal medicines that can be contained are the same as those that can be contained in the granules.
<Enzymes>
Examples of such enzymes include trypsin, α-chymotrypsin, bromelain, papain, protease, proctase, serratiopeptidase, lysozyme, and pepsin.
<Pigments and minerals>
Examples of the pigments and minerals include titanium oxide, talc, clay, kaolin, red iron oxide, yellow iron oxide, mica, titanium dioxide, zinc oxide, bentonite, zeolite, silicic anhydride, metasilicic acid, neutral clay, and coated particles (granules) thereof. Among the above pigments and minerals, when the tablet of the present invention is used as a bath additive, it is preferable to contain titanium oxide, which is also suitable as a formulation auxiliary.
<Dyes>
Examples of legal pigments include Blue No. 1, Blue No. 2, Red No. 102, Red No. 106, Red No. 227, Red No. 230 (1), Yellow No. 4, Yellow No. 5, Yellow No. 202 (1), Green No. 3, Green No. 201, Green No. 204, Orange No. 205, etc., as well as natural pigments such as chlorophyll, riboflavin, annatto, and anthocyanin.
<Vitamins and their derivatives>
Examples of such ingredients include vitamin A, vitamin B, vitamin C, vitamin D, vitamin E, vitamin F, vitamin H, pantothenic acid, nicotinic acid or a derivative thereof, vitamin E nicotinate, tocopherol acetate, sodium ascorbate, etc. These may also be contained as moisturizing ingredients.

<Seaweed extracts>
Examples of such extracts include those obtained from green algae such as Ulva pertusa, Millet, Usubaonori, Hitsugina, Porphyra japonica, Laverwort, Heliwazuta, Hanemochi, and Nagamiru, brown algae such as Sea fan, Amigusa arborescens, Mozuku, Iroro, Matsumo, Iwahige, Habanori, Urushigusa, Ecklonia japonica, Laminaria japonica, Wakame, Tororokobu, Hijiki, Eisenia bicolor, Sargassum, and Umitorano, and red algae such as Marubaamanori, Asakusa nori, Susabinori, Umizomen, Hirakusa, Makusa, Triassic alga, Hanafunori, Fukurofunori, Tosakanori, Togekirinsai, Akabaginnansou, Kotojitsunomata, Tsunomata, Ayanishiki, Makuri, Egonori, Gracilaria gracilis, and Ibarano. These can also be contained as moisturizing ingredients.
<Plant extracts>
Examples of the extracts include aloe extract, green tea extract, loofah water, chamomile extract, licorice extract, comfrey extract, eucalyptus extract, royal jelly extract, lemon extract, rosehip extract, peach leaf extract, etc. There is no particular limitation on the extraction method. These can also be contained as moisturizing ingredients or fragrance ingredients.

<Cooling substances>
Examples of the menthol include menthol derivatives such as menthol, camphor, and thymol, monocyclic compounds, bicyclic alcohols, tricyclic alcohols, tricyclic amides, and peppermint oil.
<Moisturizing ingredients>
Examples of such ceramides include ceramide, ceramide derivatives, and ceramide analogues; organic acid salts such as sodium lactate, disodium tartrate, sodium pyrrolidone carboxylate, and disodium glutamate; polyhydric alcohols such as isoprene glycol, propylene glycol, 1,3-butylene glycol, glycerin, xylose, xylitol, and sorbitol; water-soluble polymers such as polyvinyl alcohol, sodium alginate, and polyvinylpyrrolidone, mucopolysaccharides such as chondroitin sulfate and hyaluronic acid, collagen and its derivatives, proteins, keratin, fibroin, and hydrolysates thereof; fatty acid esters such as isopropyl myristate and isopropyl palmitate, shea butter, squalane, placenta, arbutin, casein, silk, and honey.

<Solvent>
Purified water, ion-exchanged water, alcohols such as ethanol, propanol, and benzyl alcohol, polyhydric alcohols such as ethylene glycol, diethylene glycol, dipropylene glycol, glycerin, and 1,3-butanediol, ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monopropyl ether, diethylene glycol monobutyl ether, diethylene glycol monoisobutyl ether, triethylene glycol monobutyl ether, propylene glycol monomethyl ether, propylene glycol dimethyl ether, dipropylene glycol Examples of the glycol ethers include glycol ethers such as propylene glycol monomethyl ether, tripropylene glycol monomethyl ether, tripropylene glycol monobutyl ether, propylene glycol monopropyl ether, dipropylene glycol monopropyl ether, propylene glycol monobutyl ether, propylene glycol-tert-butyl ether, dipropylene glycol monobutyl ether, dipropylene glycol dimethyl ether, phenyl carbitol, phenyl cellosolve, and benzyl carbitol; paraffins such as n-paraffin; esters such as diethyl phthalate, benzyl benzoate, triethyl citrate, and isopropyl myristate; and others such as 3-methyl-4-methoxybutanol, N-methylpyrrolidone, and propylene carbonate.

<Surfactant>
Examples of such surfactants include nonionic surfactants such as polyoxyethylene alkyl ethers, polyoxyethylene hydrogenated castor oil, polyoxyethylene polyoxypropylene copolymers, polyoxyethylene fatty acid esters, and sorbitan fatty acid esters; anionic surfactants such as fatty acid esters such as soap bases, sodium α-olefin sulfonate, sodium lauryl sulfate, polyoxyethylene sodium lauryl sulfate, and sodium coconut oil fatty acid methyl taurate; amphoteric surfactants such as alkyl betaines, alkylamidopropyl betaines, and 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaines; and cationic surfactants such as alkylamine salts and quaternary ammonium salts.

<Anti-fading agent>
Examples include amino acids such as glycine, alanine, glutamic acid, and the like; salicylic acid and its salts.
<pH Adjuster>
Examples include disodium hydrogen phosphate, trisodium phosphate, disodium hydrogen citrate, and trisodium citrate.
<Fungicide>
Examples of such active ingredients include isopropylmethylphenol, triclosan, dichloroisocyanuric acid, silver zeolite, cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, chlorhexidine chloride, hinokitiol, phenol, glycyrrhizinate and derivatives thereof.
＜Other＞
Examples of such sugars include glucose, sucrose, trehalose, phytocollage, isoflavones, paraoxybenzoic acid esters, vegetable or fruit extracts, and deep sea water.
The content of the above-mentioned optional components may be appropriately set within a range that does not impair the effects of the present invention. In addition, the tablet of the present invention may be covered with a known water-soluble film or the like, if necessary, depending on the application.

The present invention will be specifically described in the following examples, but the present invention is not limited to these examples.

<Reference test 1: Granule condition confirmation test>
[Reference test granule 1]
The following five types of granules A, D, and E were crushed with a hammer, granule B was cut with scissors, and granule C was crushed in a sieve. These were then classified by sieving into four particle sizes (a: 2.0 mm or more and less than 2.36 mm, b: 1.4 mm or more and less than 2.0 mm, d: 0.5 mm or more and less than 1.0 mm, e: less than 0.5 mm) and designated as reference test granule 1.
Granule A: flake-shaped L-menthol Granule B: petal-shaped solid bath additive (commercially available)
Granule C: freeze-dried instant coffee (commercially available)
Granule D: Rock salt Granule E: Rice grains The above-mentioned Reference Test Granule 1 was "loosely" filled to the brim in a container (100 mL) without tapping, and the weight of the filled granules was measured. This measurement was divided by 100 to calculate the bulk density.
[Reference test sample 1]
Thirty tablets of the above-mentioned Reference Test Granule 1, 30 parts by weight of sodium bicarbonate, 6.6 parts by weight of sodium carbonate, 25.7 parts by weight of sodium sulfate, 35 parts by weight of succinic acid, 2 parts by weight of binder, and 0.7 parts by weight of others (flavors, colorants, etc.) were compressed into tablets using a single-punch tablet press (manufactured by Shiga Seisakusho) at a pressure of approximately 98 kN (approximately 10 t) to prepare a cylindrical Reference Test Sample 1 having a diameter of 50 mm, a thickness of approximately 15 mm, and a total weight of 45 g.

[Test method]
One tablet of 45 g of Reference Test Sample 1 compressed by a tablet press was dropped into 200 L of hot water at 40° C. (bathtub: approximately 0.68 m×1.1 m×height 0.46 m), and while all of Reference Test Sample 1 was dissolved, the number of granules that floated to the surface of the bath water was counted, and the floating rate (%) of the granules was calculated. The test was performed three times, and the average value of the floating rate (%) of the granules was evaluated by the following evaluation method.
[Evaluation method]
○: The floating rate (%) of the granules is 50% or more. ×: The floating rate (%) of the granules is less than 50%. Table 1 shows the average particle size, bulk density, and average floating rate (%) of the granules for reference test granule 1, as well as the evaluation results.

The results in Table 1 confirm that in order for the granules contained in effervescent tablets to float to the surface of the bath water, it is important that the particle size and bulk density of the granules are within a specific range.

<Reference test 2: Foaming condition confirmation test>
[Reference test granules 2]
The particle size b (1.4 mm or more and less than 2.0 mm) of granule B used in the above "Reference test 1: Granule condition confirmation test" was designated as reference test granule 2 (bulk specific gravity: 0.26 g/mL).
[Reference test sample 2]
(Formulation 1)
Thirty tablets of the above-mentioned Reference Test Granule 2, 30 parts by weight of sodium bicarbonate, 6.6 parts by weight of sodium carbonate, 25.7 parts by weight of sodium sulfate, 35 parts by weight of succinic acid, 2 parts by weight of binder, and 0.7 parts by weight of others (flavors, colorants, etc.) were compressed into tablets using a single-punch tablet press (manufactured by Shiga Seisakusho) at a pressure of about 98 kN (about 10 t) to prepare a cylindrical Reference Test Sample 2 (Formulation 1) having a diameter of 50 mm, a thickness of about 15 mm, and a total weight of 45 g.
(Formulation 2)
Thirty tablets of the above-mentioned Reference Test Granule 2, 50 parts by weight of sodium bicarbonate, 6.6 parts by weight of sodium carbonate, 15.7 parts by weight of sodium sulfate, 25 parts by weight of succinic acid, 2 parts by weight of binder, and 0.7 parts by weight of others (flavors, colorants, etc.) were compressed into tablets using a single-punch tablet press (manufactured by Shiga Seisakusho) at a pressure of about 98 kN (about 10 t) to prepare a cylindrical Reference Test Sample 2 (Formulation 2) having a diameter of 50 mm, a thickness of about 15 mm, and a total weight of 45 g.
(Formulation 3)
Thirty tablets of the above-mentioned Reference Test Granule 2, 30 parts by weight of sodium bicarbonate, 6.6 parts by weight of sodium carbonate, 53.7 parts by weight of sodium sulfate, 7 parts by weight of succinic acid, 2 parts by weight of binder, and 0.7 parts by weight of others (flavors, colorants, etc.) were compressed into tablets using a single-punch tablet press (manufactured by Shiga Seisakusho) at a pressure of about 98 kN (about 10 t) to prepare a cylindrical Reference Test Sample 2 (Formulation 3) having a diameter of 50 mm, a thickness of about 15 mm, and a total weight of 45 g.

[Test method]
(Amount of carbon dioxide generated, dissolution time of effervescent tablets)
One tablet of 45 g of Reference Test Sample 2 compressed with a tablet press was placed in a cylindrical metal wire basket (diameter 10 cm x height 10 cm) and this was then immersed in 200 L of hot water at 40°C (bathtub: approximately 0.68 m x 1.1 m x height 0.46 m). A funnel was placed just above the top surface of the metal wire basket in the water to capture all of the generated gas (carbon dioxide) in a measuring cylinder, and the amount of carbon dioxide generated (mL) and the time (seconds) until the entire amount of Reference Test Sample 2 was dissolved were measured.
(carbon dioxide generation capacity)
The carbon dioxide gas generating capacity was calculated using the following formula.
[a formula]
Carbon dioxide gas generating capacity = the above "amount of carbon dioxide gas generated (mL)" ÷ the above "dissolution time of the effervescent tablet (seconds)"
(surfacing rate)
One tablet of 45 g of Reference Test Sample 2 compressed by a tablet press was dropped into 200 L of hot water at 40° C., the number of granules that floated to the surface of the bath water was counted, and the floating rate (%) of the granules was calculated. The test was performed three times, and the average value of the floating rate (%) of the granules was evaluated by the following evaluation method.
[Evaluation method]
A: The floating rate (%) of granules is 50% or more.
×: The floating rate (%) of the granules is less than 50%. Table 2 shows the amounts of sodium bicarbonate and succinic acid in reference test sample 2, the amount of carbon dioxide gas generated (mL), the dissolution time (seconds) of the effervescent tablet, the carbon dioxide gas generating power, and the average floating rate (%) of the granules, as well as the evaluation results.

The results in Table 2 confirm that in order for the granules contained in the effervescent tablet to rise to the surface of the bath water, a certain level of carbon dioxide gas generation power, calculated from the amount of carbon dioxide gas generated by the effervescent tablet and the dissolution time of the effervescent tablet, is required.

<Granule floating confirmation test for granule-containing effervescent tablets>
Example 1
Granules of Example 1 having a particle size of 1.0 mm or more and less than 1.4 mm and a bulk density of 0.58 g/mL were prepared by dry granulation using 57.6 parts by weight of carbonates (sodium bicarbonate and sodium carbonate), 12.0 parts by weight of sulfates such as sodium sulfate, 29.6 parts by weight of binder, and 0.8 parts by weight of others (flavors, colorants, etc.).
52.8 parts by weight of sodium bicarbonate, 7.6 parts by weight of sodium carbonate, 20.7 parts by weight of sodium sulfate, 15.5 parts by weight of succinic acid, 2.0 parts by weight of binder, and 1.4 parts by weight of others (flavors, colorants, etc.) were added to 30 granules of Example 1 above and mixed uniformly. The mixture was compressed at a pressure of about 98 kN (about 10 t) using a single-punch tablet press to produce cylindrical effervescent tablets of Example 1 having a diameter of 50 mm, a thickness of about 15 mm, and a total weight of 45 g.

<Examples 2 to 8, Comparative Examples 1 to 5>
The effervescent tablets of Examples 2 to 8 and Comparative Examples 1 to 5 were prepared in the same manner as in Example 1 using the blend amounts shown in Table 3 (the numbers in Table 3 represent weight percentages).
Using the obtained effervescent tablets (Examples 1 to 8, Comparative Examples 1 to 5), the test was carried out three times in the same manner as in the above "Reference Test 2: Effervescent Condition Verification Test", and evaluation was carried out based on the amount of carbon dioxide gas generated (mL), the dissolution time of the effervescent tablets (seconds), the carbon dioxide gas generating power, the floating rate of the granules (%), and the average value of the floating rate of the granules (%). For the dissolution time of the effervescent tablets (seconds), the dissolution time of the entire amount of the effervescent tablets was measured.
The tableting formulation amounts, granule particle sizes and bulk gravities, respective amounts of carbon dioxide gas generated (mL), dissolution times (seconds) of the effervescent tableting, carbon dioxide gas generating power, and granule floating rates (%) for Examples 1 to 8 and Comparative Examples 1 to 5 are shown in Table 3 for Examples 1 to 8 and Table 4 for Comparative Examples 1 to 5.
In addition, the granule particle sizes a to e in Tables 3 and 4 refer to the following ranges.
Particle diameter a: 2.0 mm or more and less than 2.36 mm Particle diameter b: 1.4 mm or more and less than 2.0 mm Particle diameter c: 1.0 mm or more and less than 1.4 mm Particle diameter d: 0.5 mm or more and less than 1.0 mm Particle diameter e: less than 0.5 mm

As shown in Table 3, it was confirmed that effervescent tablets containing granules with a particle size of 0.5 mm or more and a bulk density of 0.7 g/mL or less have a carbon dioxide gas generating capacity of 1.0 mL/sec or more during use, and as the carbon dioxide gas effervesces, 50% or more of the granules float and spread to the bath water surface. In particular, it was revealed that the granule floating rate (%) is dramatically improved when the carbon dioxide gas generating capacity is 2.0 mL/sec or more (Examples 2, 4, 7, and 8).
On the other hand, as shown in Table 4, it was confirmed that even in effervescent tableting containing granules with a particle size of 0.5 mm or more and a bulk density of 0.7 g/mL or less, if the carbon dioxide gas generating power during use is lower than 1.0 mL/sec (Comparative Examples 1 to 4), the granule floating rate (%) does not reach 30%. It was also revealed that, even if the effervescent tableting has a carbon dioxide gas generating power during use of 1.0 mL/sec or more, if the particle size of the blended granules is less than 0.5 mm (Comparative Example 5), the granules do not float at all.

The effervescent tablet of the present invention has the effect that, when it is dropped into water, the granules rise to the water surface together with the effervescence of the generated carbon dioxide gas and are dispersed widely.
In addition, when the effervescent tablet of the present invention is used as a bath additive, the granules rise to the surface of the bath water as the carbon dioxide gas effervesces and spread widely, allowing the bather to visually confirm the presence of the ingredients contained in the granules, thereby enabling the bather to not only feel the effects of the ingredients but also to feel them visually.
In other words, the effervescent tablet for bath additives of the present invention is useful because it provides a relaxing effect that can be felt both physically and visually in addition to the warm bath effect and skin care effect.

Claims (3)

The composition contains granules having a particle size of 0.5 mm or more and a bulk density of 0.7 g/mL or less,
An effervescent tablet for bath additives, characterized in that the carbon dioxide gas generating capacity during use is 1.0 mL/sec or more. The composition contains granules having a particle size of 1.0 mm or more and a bulk density of 0.7 g/mL or less,
An effervescent tablet characterized in that the carbon dioxide gas generating capacity during use is 1.0 mL/sec or more. The effervescent tablet according to claim 1 or 2 , further comprising a carbonate and an organic acid.