JP7477806B2 - Mixed injection management system, mixed injection management program, and mixed injection management method - Google Patents

Description

The present invention relates to a mixed injection management system, a mixed injection management program, and a mixed injection management method that support the mixed injection of drugs such as anticancer drugs.

There is a known injection mixing device that performs an injection mixing operation in which a drug such as an anticancer drug contained in a drug container such as an ampule or vial is taken with a syringe and the drug is injected into an infusion bag containing an infusion (see, for example, Patent Document 1). With this type of injection mixing device, the injection mixing operation is performed inside a safety cabinet set to negative pressure in order to prevent exposure to the drug such as the anticancer drug.

JP 2012-250016 A

However, if the amount of medicine to be collected in a mixing operation is not an integer multiple of the amount of medicine contained in the medicine container, some medicine will remain in the medicine container after the mixing operation. Therefore, in order to make effective use of the remaining medicine remaining in the medicine container, it is possible to use the remaining medicine in another mixing operation in which the same type of medicine is to be collected.

However, it is generally not permitted to take containers containing residual drugs, such as anticancer drugs, out of a safety cabinet. Therefore, in a situation where multiple safety cabinets are installed, residual drugs generated during a mixed injection operation performed in one safety cabinet cannot be used in a mixed injection operation performed in another safety cabinet, and the residual drugs may go to waste.

The object of the present invention is to provide a mixed injection management system, a mixed injection management program, and a mixed injection management method that can support the efficient use of medicines stored in medicine containers.

The mixed injection management system according to the present invention includes a distribution processing unit that distributes multiple preparation data related to the mixed injection work of collecting medicine and injecting it into an infusion container to multiple mixed injection work units where the mixed injection work is performed based on remaining medicine generated in a preceding mixed injection work, and a presentation processing unit that presents information regarding the distribution result by the distribution processing unit.

The mixed injection management program of the present invention is a mixed injection management program for causing one or more processors to execute a sorting step of sorting multiple preparation data related to the mixed injection work of collecting medicine and injecting it into an infusion container to multiple mixed injection work units where the mixed injection work is performed based on remaining medicine generated in a preceding mixed injection work, and a presentation step of presenting information regarding the sorting result in the sorting step.

The mixed injection management method according to the present invention includes a sorting step of sorting a plurality of preparation data related to the mixed injection work of collecting medicines and injecting them into an infusion container to a plurality of mixed injection work units where the mixed injection work is performed based on the remaining medicines generated in the preceding mixed injection work, and a presentation step of presenting information regarding the sorting results in the sorting step.

The present invention provides a mixed injection management system, a mixed injection management program, and a mixed injection management method that can support the efficient use of medicines stored in medicine containers.

FIG. 1 is a block diagram showing an example of a mixed injection management system according to an embodiment of the present invention. FIG. 2 is a block diagram showing a system configuration of a mixed injection assistance device according to an embodiment of the present invention. FIG. 3 is a perspective view showing the external configuration of the mixed injection support device according to the embodiment of the present invention. FIG. 4 is a diagram showing a state in which a safety cabinet used in the mixed injection support device according to the embodiment of the present invention is used. FIG. 5 is a block diagram showing a system configuration of the automatic co-infusion device according to the embodiment of the present invention. FIG. 6 is a perspective view showing the external configuration of the automatic co-infusion device according to the embodiment of the present invention. FIG. 7 is a perspective view of the automatic co-infusion device according to the embodiment of the present invention with the main door open. FIG. 8 is a flowchart showing an example of a procedure of a mixed injection management process executed in the mixed injection management system according to the embodiment of the present invention. FIG. 9 is a flowchart showing an example of a procedure of a distribution process executed in the mixed injection management system according to the embodiment of the present invention. FIG. 10 is a diagram showing an example of a distribution screen displayed in the mixed injection management system according to the embodiment of the present invention. FIG. 11 is a diagram showing an example of a distribution screen displayed in the mixed injection management system according to the embodiment of the present invention. FIG. 12 is a diagram showing an example of a distribution screen displayed in the mixed injection management system according to the embodiment of the present invention. FIG. 13 is a diagram showing an example of a remaining medicine screen displayed in the mixed injection management system according to the embodiment of the present invention. FIG. 14 is a diagram showing an example of a remaining medicine screen displayed in the mixed injection management system according to the embodiment of the present invention. FIG. 15 is a diagram showing an example of a remaining medicine screen displayed in the mixed injection management system according to the embodiment of the present invention. FIG. 16 is a block diagram showing a system configuration of a mixed injection assistance device according to an embodiment of the present invention. FIG. 17 is a perspective view showing the external configuration of a mixed injection assistance device according to an embodiment of the present invention. FIG. 18 is a perspective view showing an external configuration of the medicine management unit according to the embodiment of the present invention. FIG. 19 is a plan view showing the external configuration of the medicine management unit according to the embodiment of the present invention. FIG. 20 is a flowchart showing an example of a procedure for a remaining medicine storage process executed in the mixed injection management system according to the embodiment of the present invention. FIG. 21 is a diagram showing an example of remaining drug management information used in the mixed injection management system according to the embodiment of the present invention. FIG. 22A is a diagram for explaining a reporting method in the medicine management unit according to an embodiment of the present invention. FIG. 22B is a diagram for explaining a reporting method in the medicine management unit according to an embodiment of the present invention. FIG. 22C is a diagram for explaining a reporting method in the medicine management unit according to an embodiment of the present invention. FIG. 22D is a diagram for explaining a reporting method in the medicine management unit according to an embodiment of the present invention. FIG. 23 is a flowchart showing an example of a procedure for a remaining medicine utilization process executed in the mixed injection management system according to the embodiment of the present invention. FIG. 24 is a flowchart showing an example of a procedure for a remaining medicine utilization process executed in the mixed injection management system according to the embodiment of the present invention. FIG. 25A is a diagram showing an example of a guidance screen displayed in the mixed injection management system according to an embodiment of the present invention. FIG. 25B is a diagram showing an example of a guidance screen displayed in the mixed injection management system according to an embodiment of the present invention. FIG. 26A is a diagram showing an example of a registration screen displayed in the mixed injection management system according to an embodiment of the present invention. FIG. 26B is a diagram showing an example of a registration screen displayed in the mixed injection management system according to an embodiment of the present invention. FIG. 27 is a diagram showing an example of a setting screen displayed in the mixed injection management system according to the embodiment of the present invention. FIG. 28 is a diagram showing an example of a form output by the mixed injection management system according to the embodiment of the present invention. FIG. 29 is a diagram showing an example of an output screen displayed in the mixed injection management system according to the embodiment of the present invention.

The following describes an embodiment of the present invention with reference to the attached drawings to facilitate understanding of the present invention. Note that the following embodiment is an example of the present invention and does not limit the technical scope of the present invention.

As shown in FIG. 1, a mixed injection management system 1 according to an embodiment of the present invention includes a mixed injection management device 2, one or more client terminals 3, one or more mixed injection support devices 4, and one or more automatic mixed injection devices 5. Here, the mixed injection management system 1 is an example of a mixed injection management system according to the present invention. The mixed injection management device 2 alone may be regarded as the mixed injection management system according to the present invention. Also, the mixed injection support device 4 alone may be regarded as the mixed injection management system according to the present invention.

The mixed injection management device 2, the client terminal 3, the mixed injection support device 4, and the automatic mixed injection device 5 are connected to each other via a communication network N1 such as a LAN or the Internet, wirelessly or by wire, so as to be able to communicate with each other. In addition, a higher-level system 6, such as an electronic medical record system or a prescription input terminal, which inputs prescription data to the mixed injection management device 2, is connected to the mixed injection management device 2 via the communication network N1. For example, the prescription data includes the date of prescription issuance, patient ID, patient name, patient date of birth, drug information (drug code, drug name, dosage, etc.), method of taking (oral administration, external use, etc.), usage information (three times a day after each meal, etc.), medical treatment type (outpatient, hospitalization, etc.), medical department, ward, and hospital room. It is also possible that the mixed injection management device 2 can read prescription data from a prescription, or that the mixed injection management device 2 can input prescription data by a user operation.

[Mixed injection management device 2]
The mixed injection management device 2 is a personal computer including a control unit 21, a storage unit 22, a communication I/F 23, a display unit 24, an operation unit 25, and a drive device 26. The mixed injection management device 2 is disposed inside or outside a medical institution in which the mixed injection management system 1 is used.

The control unit 21 has control devices such as a CPU, a ROM, a RAM, and an EEPROM (registered trademark, the same applies below). The CPU is a processor that executes various arithmetic processes. The ROM is a non-volatile storage unit in which information such as a control program for causing the CPU to execute various processes is stored in advance. The RAM is a volatile storage unit, and the EEPROM is a non-volatile storage unit. The RAM and the EEPROM are used as temporary storage memories (work areas) for the various processes executed by the CPU. The control unit 21 then uses the CPU to execute various processes in accordance with various control programs (for example, a mixed injection management program described below) that are stored in advance in the ROM, the EEPROM, or the storage unit 22.

The storage unit 22 is a storage unit such as a HDD (Hard Disk Drive) or SSD (Solid State Drive) that stores various data. Specifically, a mixed injection management program for causing a computer such as the control unit 21 to execute the mixed injection management process (see FIG. 8) described below is stored in advance in the storage unit 22. Note that the present invention may be understood as an invention of the mixed injection management program for causing a computer such as the control unit 21 to execute the mixed injection management process, or a computer-readable recording medium on which the mixed injection management program is recorded. The present invention may also be understood as an invention of a mixed injection management method for executing each processing procedure of the mixed injection management process in the mixed injection management device 2, etc.

In addition, the storage unit 22 also stores various databases, such as a pharmaceutical master, a patient master, and a user master. Furthermore, the storage unit 22 also stores a drug database in addition to the pharmaceutical master.

The pharmaceutical master contains information about each pharmaceutical, such as the pharmaceutical ID, pharmaceutical code, pharmaceutical name, YJ code, JAN code (or RSS code), vial code, classification (dosage form: powder, tablet, liquid, topical medication, etc.), tablet shape (capsule, spherical tablet, flat tablet (disk-shaped tablet), etc.), tablet color, tablet size, specific gravity, pharmaceutical type (ordinary medicine, poison, narcotic, highly toxic drug, antipsychotic, therapeutic drug, etc.), compounding variations, excipients, and precautions.

The user master contains information about users, such as the pharmacy name, pharmacist name, pharmacist ID, password, user group, and processing authority. The patient master contains information about patients, such as the patient ID, name, sex, age, medical history, prescription drug history, family information, medical department, ward, and room.

In the drug database, information such as drug code, drug name, JAN code, RSS code, medicine bottle code, dosage form, unit, specific gravity, drug type, compounding variation, excipient drug, cautions, allergy information, package insert information, etc. are stored in association with each drug. In particular, in the drug database, for tablets, information such as tablet identification information (e.g., information for identifying the drug type of the tablet) formed on the tablet and tablet shape is stored. The drug database is read from a recording medium such as a CD or DVD by the drive device 26, for example, or received from an external device via the communication network N1, and stored in the storage unit 22. The drug database is used in the mixed injection management system 1 when importing information into various masters such as the drug master, or when referring to information on the package insert of each drug. The control unit 21 may be configured to be able to read the drug database from an external device or website via the communication network N1 as necessary. The drug database is used for updating the drug master, etc.

The communication I/F 23 is a communication interface having a network card or the like that performs wireless or wired data communication according to a predetermined communication protocol between the client terminal 3, the co-infusion support device 4, the automatic co-infusion device 5, and other external devices via the communication network N1.

The display unit 24 is a display unit such as a liquid crystal monitor that displays various information and operation screens in accordance with control instructions from the control unit 21. The operation unit 25 is an operation unit such as a keyboard, mouse, and touch panel that accepts user operations, and inputs operation signals corresponding to user operations to the control unit 21. The operation unit 25 accepts various operation inputs, such as a prescription data selection operation on the display screen displayed on the display unit 24, and a prescription data issuance operation that requests the start of dispensing of the prescription data.

The drive device 26 is capable of reading the mixed injection management program from a computer-readable recording medium 261 on which the mixed injection management program is recorded. The recording medium 261 is a CD, DVD, BD, USB memory, or the like, and the drive device 26 is a CD drive, DVD drive, BD drive, USB port, or the like. In the mixed injection management device 2, the control unit 21 uses the drive device 26 to store the mixed injection management program read from the recording medium 261 in the memory unit 22.

In the mixed injection management device 2 configured in this manner, the control unit 21 executes various processes in accordance with the mixed injection management program. The control unit 21 also has a function of generating prescription data (hereinafter referred to as preparation data) indicating the contents of the mixed injection work described below based on the prescription data, and inputting the preparation data to the mixed injection assistance device 4 and the automatic mixed injection device 5. As a result, the mixed injection assistance device 4 and the automatic mixed injection device 5 execute the mixed injection assistance process and automatic mixed injection process described below based on the preparation data.

For example, the preparation data includes patient information (patient ID, patient name, height, weight, body surface area, etc.), preparation date, preparation time, drug information (drug code, drug name, etc.), dosage (amount of drug dispensed), regimen identification information, etc. The regimen identification information is information capable of identifying regimen information, such as a therapy name (regimen name), a therapy ID, or a regimen ID. The preparation data may also include information such as doctor information, type of drug container (ampule containing drug solution, vial containing drug solution, or vial containing powdered drug), preparation content information (type and number of drug containers, syringes, and needles used in the mixed injection work), and preparation procedure information (work content, dissolved drug, solvent, amount of dissolved drug, amount of solvent, amount extracted), administration date, prescription category, medical department, and ward. The preparation data may also be the prescription data itself.

The control unit 21 displays the results of the mixed injection management process executed based on the preparation data on the client terminal 3, etc. Details of the mixed injection management process executed by the control unit 21 will be described later.

[Client Terminal 3]
The client terminal 3 is a personal computer including a control unit 31, a storage unit 32, a communication I/F 33, a display unit 34, and an operation unit 35. Each of the client terminals 3 is an operation terminal that is disposed in a medical institution in which the mixed injection management system 1 is used and is operated by a user such as a pharmacist.

The control unit 31 has control devices such as a CPU, a ROM, a RAM, and an EEPROM. The CPU is a processor that executes various arithmetic operations. The ROM is a non-volatile storage unit in which information such as control programs for causing the CPU to execute various processes is stored in advance. The RAM is a volatile storage unit, and the EEPROM is a non-volatile storage unit. The RAM and the EEPROM are used as temporary storage memories (work areas) for the various processes executed by the CPU. The control unit 31 then uses the CPU to execute various processes in accordance with the various control programs stored in advance in the ROM, the EEPROM, or the storage unit 32.

The storage unit 32 is a non-volatile storage unit such as a hard disk or SSD in which various application programs and various data executed by the control unit 31 are stored. Specifically, application programs such as an operating system (OS) and browser software are stored in the storage unit 32. The browser software is application software for displaying various operation screens and the like on the display unit 34 by accessing the mixed injection management device 2 via the communication network N1, and for transmitting input operations on the operation screen using the operation unit 35 to the mixed injection management device 2. Specifically, when address information such as a URL (Universal Resource Locator) corresponding to the mixed injection management device 2 is input to a predetermined position on the operation screen displayed by the browser software, the control unit 31 accesses the mixed injection management device 2 based on the address information.

The communication I/F 33 is a communication interface having a network card or the like that performs wireless or wired data communication according to a predetermined communication protocol between an external device such as the mixed injection management device 2 via the communication network N1.

The display unit 34 is a display unit such as a liquid crystal display or an organic EL display that displays various information according to control instructions from the control unit 31. The operation unit 35 is an operation unit that is operated by a user to input various information to the client terminal 3. Specifically, the operation unit 35 includes a keyboard, a mouse (pointing device), and a touch panel that accept input operations on various operation screens displayed on the display unit 34.

In the mixed injection management system 1, the mixed injection management device 2 and the client terminal 3 constitute a server-client system, and the mixed injection management device 2 executes various processes in response to user operations of the client terminal 3. For example, the control unit 21 of the mixed injection management device 2 transmits data described in a page description language such as HTML to the client terminal 3, thereby displaying various screens on the display unit 34 of the client terminal 3. The control unit 31 of the client terminal 3 transmits an operation signal to the mixed injection management device 2 in response to an operation input to the operation unit 35.

It is also possible that a part or all of the mixed injection management program is installed in one or more of the mixed injection management device 2, the client terminal 3, and the mixed injection assistance device 4, and the mixed injection management process (see FIG. 8) described below is executed by the mixed injection management device 2, the client terminal 3, the mixed injection assistance device 4, etc. in cooperation with each other.

[Mixed injection support device 4]
Next, the configuration of the mixed injection support device 4 will be described with reference to Figures 2 to 4. As shown in Figures 2 and 3, the mixed injection support device 4 includes a control unit 41, an operation display unit 42, a first reading unit 43, a printer 44, a foot switch unit 45, a second reading unit 46, and a weighing unit 47. The mixed injection support device 4 is used to improve the efficiency of mixed injection work performed by an operator such as a doctor or a pharmacist.

The co-infusion work is a work of injecting a drug (medicine, formulation) such as an anticancer drug indicated in the preparation data from one or more drug containers that contain a predetermined amount of the drug into an infusion container. Specifically, in the co-infusion work, the worker may perform a work of aspirating a drug solution from a drug container with a syringe and injecting it into an infusion bag that contains a dissolving solution such as saline. In addition, in the co-infusion work, the worker may perform a work of aspirating a dissolving solution such as saline from an infusion bag with a syringe and injecting it into a drug container that contains a powdered medicine to dissolve the powdered medicine, and then aspirating the dissolved drug solution with a syringe and injecting it into the infusion bag.

As shown in FIG. 3, the second reading unit 46 and the weighing unit 47 are disposed in the work room 101 of the safety cabinet 100 where the worker performs the co-injection work. On the other hand, the control unit 41, the operation display unit 42, the first reading unit 43, the printer 44, and the foot switch unit 45 are disposed outside the work room of the safety cabinet 100. Note that the operation display unit 42, the printer 44, etc. may be provided in the work room 101 of the safety cabinet 100.

The safety cabinet 100 or the work room 101 is an example of a mixing work section of the present invention. The safety cabinet 100 or the work room 101 is also an example of a manual work section of the present invention.

The safety cabinet 100 includes a work chamber 101 separated by a transparent glass door 102 on the front. The glass door 102 is supported at a position where an opening 103 is formed below, and workers can access the work chamber 101 from the opening 103. The safety cabinet 100 is also provided with an air purifier 104 having a HEPA filter for purifying the air in the work chamber 101 and discharging it.

As shown in FIG. 4, the worker inserts both hands into the work chamber 101 through the open portion 103 and performs the mixing operation of the medicines while visually checking the inside of the work chamber 101. When mixing non-toxic medicines (medicines, preparations) in the mixing support device 4, a clean bench or the like may be used instead of the safety cabinet 100. The work chamber of the clean bench is also an example of the mixing operation section of the present invention.

The second reading unit 46 provided in the safety cabinet 100 is a code reading device capable of reading code information such as a one-dimensional code or a two-dimensional code attached to a drug container of the drug used in the mixed injection operation. The two-dimensional code is, for example, a QR code (registered trademark). The code information includes identification information for identifying the type of the drug. The code information read by the second reading unit 46 is input to the control unit 41.

The weighing unit 47, which is also provided in the safety cabinet 100, is an electronic balance used for various measurements in the co-injection work. The weighing results by the weighing unit 47 are input to the control unit 41 in real time. The weighing unit 47 also inputs stability information indicating whether the weighing results are stable or not to the control unit 41. This allows the control unit 41 to obtain the weighing results by the weighing unit 47 and information such as whether the weighing results are stable or not. The control unit 41 may be configured to actively read out the weighing results by the weighing unit 47 and information such as whether the weighing results are stable or not.

The control unit 41 is connected to the mixed injection management device 2 wirelessly or wired via the communication network N1 so as to be able to communicate with the mixed injection management device 2. The control unit 41 can acquire the preparation data from the mixed injection management device 2.

The control unit 41 is a computer having a CPU 411, a RAM 412, a storage unit 413, and the like. The CPU 411 is a processor that executes various arithmetic processing. The RAM 412 is a volatile storage unit, and is used as a temporary storage memory (work area) for various processing executed by the CPU 411. The storage unit 413 is a non-volatile storage unit such as an HDD or SSD that stores information such as control programs for causing the CPU 411 to execute various processing. The control unit 41 uses the CPU 411 and the RAM 412 to execute various processing in accordance with various control programs pre-stored in the storage unit 413.

The storage unit 413 includes storage areas such as a data area, a program area, and a master area. The storage unit 413 may include multiple storage media such as a HDD and a semiconductor memory, and the data area, the program area, and the master area may be distributed across multiple storage media.

The preparation data acquired from the mixed injection management device 2 is accumulated and stored in the data area. The control unit 41 can also newly register or edit the preparation data in response to a user operation. The data area also stores history data indicating the contents of the mixed injection work performed by an operator according to the preparation data in association with the preparation data. For example, the history data includes the operator of the mixed injection work, the start time of the work, the end time of the work, and images taken during the mixed injection work.

The program area stores a control program for causing the control unit 41 to execute a mixed injection support process, which will be described later. The program area also stores application programs such as an operating system (OS) and browser software.

The master area stores various master information such as a drug master, a patient master, a ward master, a doctor master, and a pharmacist master. For example, the drug master includes information such as a drug ID, drug name, drug code, medicine bottle code, classification (dosage form: powder, tablet, liquid, topical medicine, etc.), specific gravity, drug type (ordinary medicine, anticancer drug, poison, narcotic, powerful drug, antipsychotic, therapeutic drug, etc.), compounding changes, excipient drug, precautions, type of drug container (ampule, vial), drug capacity per drug container (predetermined amount), and drug container weight. The drug ID is an identification code such as a YJ code, a JAN code, or an RSS code.

The operation display unit 42 includes a display unit such as a liquid crystal display or an organic EL display that displays various information in accordance with control instructions from the control unit 41, and an operation unit that is operated by the user to input various information to the control unit 41.

Specifically, the operation unit of the operation display unit 42 is a touch panel that accepts touch operations on various operation screens displayed on the display unit. The operation display unit 42 may be a tablet terminal or the like. The operation unit may also include a keyboard and a mouse (pointing device) that accept input operations on the various operation screens displayed on the display unit. Furthermore, the operation unit may also include a voice input device that accepts input of various information by voice recognition.

The first reading unit 43 is a code reading device capable of reading code information such as a one-dimensional code or a two-dimensional code printed on a preparation receipt (prescription instruction sheet) corresponding to the preparation data. The code information includes identification information for identifying the preparation data. The code information read by the first reading unit 43 is input to the control unit 41. The control unit 41 then identifies the preparation data to be subjected to the current mixing operation based on the code information read from the preparation receipt using the first reading unit 43. Specifically, the control unit 41 reads the identification information of the preparation data from the code information, and selects the preparation data corresponding to the identification information from the data area of the storage unit 413. Note that the control unit 41 may acquire the preparation data from the code information.

The printer 44 is used by the control unit 41 to print various information. For example, it is used to print the preparation slip corresponding to the preparation data executed by the control unit 41, or to print history data of the co-injection work executed according to the preparation data. The printer 44 is also used to print a remaining medicine authentication label that includes the contents of the remaining medicine (remaining medicine) generated in the co-injection work, a one-dimensional code or a two-dimensional code indicating the contents of the remaining medicine, etc.

The foot switch unit 45 is an operation unit for an operator to input operations to the control unit 41 while performing the mixed injection work. The foot switch unit 45 includes a first foot switch 451, a second foot switch 452, and a third foot switch 453. The first foot switch 451 and the second foot switch 452 are used for operations such as selecting an item to be operated, and the third foot switch 453 is used for operations such as deciding on an item to be operated.

In addition, in the mixing operation, the worker selects the necessary work steps from, for example, the drug authentication step, the tare weight step, the dissolving liquid extraction step, the dissolving liquid measurement step, the dissolving liquid photography step, the dissolving step, the drug solution extraction step, the drug solution measurement step, the drug solution photography step, and the mixing operation step, and executes them in sequence.

The drug authentication process is a process for authenticating the drug used in the mixed injection operation, and is, for example, a process for reading the identification information of the drug using the second reading unit 46. The tare process is a process for pre-weighing only the weight of the equipment, such as a syringe, used in the mixed injection operation, and is, for example, a process for placing the syringe on the weighing unit 47.

The dissolving liquid extraction process is a process of extracting a required amount of dissolving liquid, such as physiological saline, from an infusion bag using a syringe. The dissolving liquid measurement process is a process for measuring the weight of the syringe from which the dissolving liquid has been extracted, and is a process for placing the syringe on the weighing unit 47. In the dissolving liquid measurement process, the control unit 41 measures the difference between the weight of the syringe placed on the weighing unit 47 and the weight of the syringe set by the tare weight as the weight of the dissolving liquid. The dissolving liquid photographing process is a process for photographing the syringe from which the dissolving liquid has been extracted, using an imaging unit (not shown). The dissolving process is a process for dissolving a drug when the drug is a powder, and is a process for injecting the dissolving liquid extracted by the syringe into a drug container.

The liquid medicine extraction process is a process of extracting a required amount of liquid medicine from a medicine container with a syringe. The liquid medicine measurement process is a process for measuring the weight of the syringe from which the liquid medicine has been extracted, and is a process for placing the syringe on the weighing unit 47. Note that in the liquid medicine measurement process, the control unit 41 also measures the weight of the liquid medicine as the difference between the weight of the syringe placed on the weighing unit 47 and the weight of the syringe set by the tare weight. The liquid medicine photography process is a process for photographing the syringe from which the liquid medicine has been extracted with the photography unit. The co-infusion process is a process for injecting the liquid medicine in the syringe into the infusion bag.

The control unit 41 executes a mixing support process based on a control program stored in the memory unit 413. In the mixing support process, the control unit 41 sequentially displays the work steps required for the mixing work on the operation display unit 42 based on the preparation data that is the subject of the mixing work. This allows the worker to proceed with the work steps in order according to the display.

[Automatic co-injection device 5]
Next, the configuration of the automatic co-infusion device 5 will be described with reference to Figures 5 to 7. As shown in Figure 5, the automatic co-infusion device 5 includes a control unit 51, a medicine loading unit 54, and a co-infusion processing unit 55. In the automatic co-infusion device 5, the control unit 51 controls the operation of the co-infusion processing unit 55, thereby performing an automatic co-infusion process in which a medicine (medicine, formulation) such as an anticancer drug indicated in the preparation data is injected from one or more medicine containers containing a predetermined amount of the medicine into an infusion container.

The control unit 51 includes a first control unit 52 and a second control unit 53 that are connected to each other so as to be able to communicate bidirectionally via a communication network such as a LAN or the Internet (for example, the communication network N1). The first control unit 52 is provided on the drug loading unit 54 side, and the second control unit 53 is provided on the mixed injection processing unit 55 side. The first control unit 52 is connected to the mixed injection management device 2 via the communication network N1, and the preparation data is input to the first control unit 52 from the mixed injection management device 2.

The first control unit 52 is a personal computer including a CPU 521, a ROM 522, a RAM 523, a data storage unit 524, and an operation unit 525. The first control unit 52 is connected to various electrical components provided in the medicine loading unit 54, such as a display 541, a barcode reader 542, and an air purifier 543, which will be described later.

The CPU 521 is a processor that executes processing according to various control programs. The ROM 522 is a non-volatile memory in which programs such as BIOS executed by the CPU 521 are pre-stored. The RAM 523 is a volatile or non-volatile memory used for the expansion of various control programs by the CPU 521 and for temporary storage of data.

The data storage unit 524 is a hard disk or the like that stores various application programs and various data executed by the CPU 521. Specifically, the preparation data input from the mixed injection management device 2 is stored in the data storage unit 524. In addition, the data storage unit 524 stores various databases such as a drug master, a patient master, a doctor master, a prescription classification master, a medical department master, and a ward master. For example, the drug master includes information such as a drug code, a drug name, a JAN code (or RSS), a medicine bottle code, a classification (dosage form: powdered medicine, tablet, liquid medicine, external medicine, etc.), a specific gravity, a drug type (ordinary medicine, anticancer drug, poison, narcotic drug, powerful drug, antipsychotic drug, therapeutic drug, etc.), a compounding change, an excipient drug, a caution, a type of medicine container (ampule, vial bottle), and a medicine capacity (predetermined amount) of a medicine container unit. Hereinafter, information indicating the medicine capacity (predetermined amount) of a medicine container unit is referred to as predetermined amount information. In addition, in the pharmaceutical master, if there are multiple types of pharmaceutical containers for the same pharmaceutical, the default amount information corresponding to each pharmaceutical container is stored.

The operation unit 525 includes various operation means such as a keyboard, mouse, or touch panel that accepts various user operations in the first control unit 52.

The second control unit 53 is a personal computer including a CPU 531, a ROM 532, a RAM 533, a data storage unit 534, an operation unit 535, etc. The second control unit 53 is connected to various electrical components such as a first robot arm 551, a second robot arm 552, and a container transport unit 553, which are provided in the mixed injection processing unit 55.

The CPU 531 is a processor that executes processing according to various control programs. The ROM 532 is a non-volatile memory in which programs such as the BIOS executed by the CPU 531 are pre-stored. The RAM 533 is a volatile or non-volatile memory used for the expansion of various control programs by the CPU 531 and for temporary storage of data.

The data storage unit 534 is a hard disk or the like that stores various application programs and various data executed by the CPU 531. For example, the data storage unit 534 stores in advance a control program for controlling the co-injection processing unit 55, etc.

The operation unit 535 includes various operation means such as a keyboard, mouse, or touch panel that accepts various user operations in the second control unit 53.

6 and 7, the drug loading section 54 is a clean bench equipped with a display 541, a barcode reader 542, and an air purifier 543. As shown in FIG. 7, the drug loading section 54 and the mixed injection processing section 55 are connected to each other via a communication opening 201 formed on the side of the mixed injection processing section 55.

The display 541 is a display means such as a liquid crystal display or an organic electroluminescence display that displays various information in response to control instructions from the first control unit 52. Specifically, the display 541 displays preparation data that is the subject of the automatic co-infusion process in the automatic co-infusion device 5. The barcode reader 542 reads a barcode written on a prescription or preparation instructions, and inputs the contents of the barcode into the first control unit 52. The air purifier 543 supplies air into the medicine loading unit 54 through a specified filter.

6, the user performs preparation work for the automatic co-infusion process to be executed by the automatic co-infusion device 5 while inserting their hands into the drug loading section 54. Specifically, the preparation work includes, for example, a loading work of placing drug containers (ampoules, vials, etc.), a syringe, and an infusion bag in predetermined positions of the container 202, and loading the container 202 into the co-infusion processing section 55.

The container 202 is then supplied to the co-infusion processing unit 55 through the communication opening 201 after the user sets the medicine container, the syringe, and the infusion bag.

As shown in FIG. 6, a main door 200 is provided on the front side of the mixed injection processing unit 55. The main door 200 is opened and closed to access the mixed injection processing chamber 203, for example, when cleaning the mixed injection processing chamber 203 provided in the mixed injection processing unit 55.

The mixed injection processing unit 55 is provided with a waste storage chamber 204 in which waste such as the drug containers and syringes used in the automatic mixed injection processing in the mixed injection processing chamber 203 is stored.

As shown in FIG. 7, the mixed injection processing chamber 203 is provided with a first robot arm 551, a second robot arm 552, a container transport unit 553, and the like, which are all jointed. The mixed injection processing chamber 203 is also provided with an ampoule cutter, a stirring device, a loading shelf, a medicine reading unit, a weighing scale, a mixed injection communication port 205, a dust cover, multiple cameras, a germicidal lamp, and the like.

The automatic co-injection device 5 or the co-injection processing chamber 203 is an example of the co-injection work unit of the present invention. The automatic co-injection device 5 or the co-injection processing chamber 203 is also an example of the automatic work unit of the present invention.

In the automatic co-infusion device 5, the co-infusion work is performed by the dual-arm first robot arm 551 and the second robot arm 552. Specifically, the second control unit 53 controls the first robot arm 551 and the second robot arm 552 to cause the first robot arm 551 and the second robot arm 552 to perform the co-infusion work. Note that the co-infusion processing unit 55 may have, for example, a configuration having one robot arm, a configuration including three or more robot arms, or a configuration without using a robot arm, as long as it has a structure capable of performing the automatic co-infusion process.

The mixed injection processing unit 55 is also provided with a container transport unit 553 that transports the container 202 supplied from the communication opening 201. The drug container (ampule, vial, etc.) and syringe placed in the container 202 are transported to the mixed injection processing chamber 203 by the container transport unit 553. The infusion bag placed in the container 202 is transported by the container transport unit 553 and held in a state where the mixed injection port of the infusion bag is positioned at the mixed injection communication port 205.

The ampoule cutter is capable of breaking off the top of the ampoule.

The stirring device is capable of stirring the vial. When powdered medicine is contained in the vial, the stirring device is used to inject an infusion or medicine into the vial to dissolve the powdered medicine and produce a mixed medicine.

The placement shelf is used to temporarily place the medicine container and the syringe during the automatic co-infusion process executed by the automatic co-infusion device 5. The placement shelf is also used as a standby position for the medicine container when medicine remains inside the medicine container after the automatic co-infusion process is executed. Of course, the standby position may be provided at a position separate from the placement shelf.

The drug reading unit is capable of reading barcodes that indicate information about the contained drug and are written on labels attached to the drug containers, such as the ampules and vials.

The weighing scale is used to measure the weight of the syringe in the automatic co-infusion process executed by the automatic co-infusion device 5, and the measurement result by the weighing scale is input to the second control unit 53. As a result, the second control unit 53 can obtain the amount of drug solution aspirated from the drug container, for example, by calculating the difference between the weight of the syringe after the drug has been aspirated from the drug container and the known weight of the syringe itself.

As shown in FIG. 7, the mixed injection communication port 205 is formed on the side wall of the mixed injection processing chamber 203. The infusion bag is held in a state where only the mixed injection port of the infusion bag is located inside the mixed injection processing chamber 203 through the mixed injection communication port 205.

The germicidal lamp is turned on, for example, three hours before the start of the automatic mixed injection process, to sterilize the inside of the mixed injection process chamber 203.

The mixed injection processing unit 55 is also provided with an exhaust system that sucks the air in the mixed injection processing chamber 203 through a slit 206 (see FIG. 7) formed in the lower part of the side wall of the mixed injection processing chamber 203 and exhausts it from an exhaust fan (not shown) provided above the mixed injection processing chamber 203. The mixed injection processing unit 55 is also provided with an air supply system that cleans the outside air from an air intake port formed in the ceiling part of the mixed injection processing chamber 203 and guides it to the mixed injection processing chamber 203, etc.

In the automatic co-infusion process executed by the automatic co-infusion device 5, the first robot arm 551 and the second robot arm 552, etc. are controlled by the second control unit 53, and a drug such as an anticancer drug indicated in the preparation data is injected into the infusion bag from one or more drug containers containing a predetermined amount of the drug.

However, if the amount of medicine to be collected in the mixed injection work is not an integral multiple of the amount of medicine contained in the medicine container, the medicine will remain in the medicine container after the mixed injection work. Therefore, in order to effectively utilize the remaining medicine remaining in the medicine container, it is possible to use the remaining medicine in another mixed injection work in which the same type of medicine is to be collected. However, it is generally not permitted to take a medicine container containing remaining medicine such as an anticancer drug out of a safety cabinet. Therefore, in a situation where multiple safety cabinets are installed, the remaining medicine generated in the mixed injection work performed in one safety cabinet cannot be used in the mixed injection work performed in another safety cabinet, and the remaining medicine may be wasted. In response to this, the mixed injection management system 1 according to this embodiment can support the efficient use of medicines contained in the medicine container.

In this embodiment, three mixing work units, two of the safety cabinets 100 and one of the automatic mixing device 5, are provided as mixing work units for performing mixing work, and each of the safety cabinets 100 is provided with the mixing support device 4. Hereinafter, one of the two safety cabinets may be referred to as "safety cabinet 1" and the other as "safety cabinet 2". The automatic mixing device 5 may be referred to as "chemoro". "Safety cabinet 1" and "safety cabinet 2" are examples of manual work units in which the mixing work is performed by a person, and "chemoro" is an example of an automatic work unit in which the mixing work is performed by a robot.

In the mixed injection management device 2, the control unit 21 is capable of executing a mixed injection management process that distributes multiple pieces of preparation data corresponding to the mixed injection work to be performed to the three mixed injection work units.

As shown in FIG. 1, the control unit 21 of the mixed injection management device 2 includes an allocation processing unit 211, a presentation processing unit 212, a remaining amount calculation processing unit 213, and a remaining amount management processing unit 214. Specifically, the control unit 21 functions as the allocation processing unit 211, the presentation processing unit 212, the remaining amount calculation processing unit 213, and the remaining amount management processing unit 214 by executing various processes according to the mixed injection management program stored in the memory unit 22.

The allocation processing unit 211 allocates a plurality of preparation data related to a mixing operation in which a drug is collected from one or more drug containers containing a predetermined amount of drug and injected into an infusion container to a plurality of independent mixing operation units in which the mixing operation is performed, based on information on the remaining drug generated in the preceding mixing operation (e.g., the presence or absence, type, amount, usable period, etc. of the remaining drug). Note that, in the mixed injection management device 2, the information on the remaining drug that the allocation processing unit 211 takes into consideration when allocating the preparation data is not limited to the information on the remaining drug generated in the mixing operation based on each of the preparation data to be allocated. For example, the allocation processing unit 211 may receive remaining drug management information described later from the mixed injection support device 4 and allocate the preparation data taking into consideration the remaining drug management information. Specifically, when allocating the preparation data, the allocation processing unit 211 may allocate preparation data that can use the remaining drug already stored in the mixing operation unit to the mixing operation unit based on the remaining drug management information.

For example, the allocation processing unit 211 allocates multiple preparation data for which mixing work is to be performed on the same day or the next day to the three mixing work units (i.e., "Safety Cabinet 1," "Safety Cabinet 2," and "Chemoro") based on the remaining drugs generated in the preceding mixing work.

Specifically, the allocation processing unit 211 preferentially allocates preparation data for a second mixing operation that uses the same type of drug as the residual drug generated in the preceding first mixing operation to the same mixing operation unit as the first mixing operation. For example, if two mixing operations using drug A are scheduled to be performed on the same day, and the first mixing operation is scheduled to be performed in "safety cabinet 2," the allocation processing unit 211 preferentially allocates preparation data corresponding to the second mixing operation to "safety cabinet 2." This allows the residual drug generated in the first mixing operation to be used in the second mixing operation without the residual drug being taken outside the mixing operation unit, making it possible to effectively utilize the residual drug.

The allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units based on predetermined allocation conditions, in addition to the remaining medicines generated in the preceding mixing work.

For example, the allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units based on the time of execution of the mixing work corresponding to each of the preparation data, as an example of the allocation condition. For example, the allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units so that multiple mixing works performed at the same or close time are not concentrated in the same mixing work unit. This makes it possible to prevent mixing works from concentrating on a specific mixing work unit and causing delays in the mixing work that should be performed in that mixing work unit.

The allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units based on the administration time of the drug collected in the mixing work, as an example of the allocation condition. For example, the allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units so that the mixing work of each of the preparation data scheduled to be administered at the same or close time is not concentrated in the same mixing work unit. This makes it possible to prevent mixing work from being concentrated in a specific mixing work unit, resulting in delays in the mixing work that should be performed in that mixing work unit.

The allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units based on the working time required for the mixing work, as an example of the allocation condition. For example, the allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units so that mixing work that requires a long working time is not concentrated in the same mixing work unit. This makes it possible to prevent mixing work from being concentrated in a specific mixing work unit and causing delays in the mixing work that should be performed in that mixing work unit.

The allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units based on the number of times that the drug is taken from the drug container in the mixing work, as an example of the allocation condition. For example, the allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units so that mixing work involving a large number of times that the drug is taken from the drug container (i.e., mixing work requiring a long working time) is not concentrated in the same mixing work unit. This makes it possible to prevent mixing work requiring a long working time from concentrating in a specific mixing work unit, resulting in delays in the mixing work that should be performed in that mixing work unit.

The allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units based on the presence or absence of use of the remaining drug in the mixing work, as an example of the allocation condition. For example, the allocation processing unit 211 may preferentially allocate preparation data corresponding to a mixing work using a remaining drug generated in a preceding mixing work to a specific mixing work unit. The allocation processing unit 211 may also allocate preparation data corresponding to a mixing work not using a remaining drug generated in a preceding mixing work to an arbitrary mixing work unit. This allows the mixing work using a remaining drug generated in a preceding mixing work to be preferentially allocated to the automatic mixing device 5 or to a specific safety cabinet 100 (for example, the safety cabinet 100 assigned to an experienced pharmacist).

The allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units based on the type of drug collected in the mixing work, as an example of the allocation condition. For example, the allocation processing unit 211 may preferentially allocate preparation data corresponding to mixing work using powdered medicine (i.e., mixing work requiring mixing work) to the automatic mixing device 5. This allows the automatic mixing device 5 to perform mixing work that requires time and effort, such as mixing work, and reduces the time and effort required by the operator (pharmacist) for the mixing work. The allocation processing unit 211 may preferentially allocate preparation data corresponding to mixing work using drugs with a high risk of exposure to the automatic mixing device 5. This can increase safety in the mixing work.

In addition, the allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units based on the drug price of the drug collected in the mixing work as an example of the allocation condition. For example, the allocation processing unit 211 may preferentially allocate preparation data corresponding to a mixing work using a drug with a high drug price to the same mixing work unit as the preceding mixing work in which the same type of remaining drug is generated. The allocation processing unit 211 may then allocate preparation data corresponding to a mixing work using a drug with a low drug price to any mixing work unit. This allows drugs with a low drug price and little need for effective use of the remaining drug to be allocated to any mixing work unit, thereby preventing mixing work from concentrating on a specific mixing work unit and delaying the mixing work to be performed in that mixing work unit. In addition, the allocation processing unit 211 may preferentially allocate preparation data corresponding to a mixing work using a drug with a high drug price to the automatic mixing device 5. This allows expensive medicines to be collected with high accuracy and without error by the automatic co-injection device 5, preventing expensive medicines from being wasted due to errors, etc.

The allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units based on the price of a closed system drug transfer system (CSTD) used in the mixing work as an example of the allocation condition. The closed system drug transfer system may be used to prevent some drugs such as anticancer drugs that have a high risk of exposure from leaking into the work room 101 of the safety cabinet 100 when the drugs are collected with a syringe in the safety cabinet 100. On the other hand, since the mixing work in the automatic mixing device 5 is performed by a robot, the closed system drug transfer system is not necessary. Therefore, the allocation processing unit 211 may determine the allocation destination for preparation data corresponding to the mixing work using some drugs such as anticancer drugs that have a high risk of exposure by comparing the cost required to perform the mixing work in the safety cabinet 100 using the closed system drug transfer system with the cost required to perform the mixing work in the automatic mixing device 5.

The allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units based on the usable period of the remaining medicine generated in the mixing work as an example of the allocation condition. The usable period is the period during which the remaining medicine can be used (collected or administered) after the remaining medicine is generated. The usable period may be set individually for each medicine. For example, in a mixing work performed at 9:00, if a medicine with the usable period set to 5 hours remains as a remaining medicine, the allocation processing unit 211 may determine the allocation destination by regarding the preparation data whose administration time is later than 14:00 as preparation data corresponding to a mixing work that does not use the remaining medicine. For example, when a dissolving liquid such as saline is injected into a medicine container containing a powdered medicine, the powdered medicine is dissolved and then collected with a syringe, it may be required to use the dissolved medicine promptly. Therefore, for such powdered medicine, the usable period may be set to a shorter time than for liquid medicine.

The allocation processing unit 211 may allocate each of the preparation data to the multiple mixing work units so that the cost required for the mixing work corresponding to the multiple preparation data (for example, the cost calculated based on the drug price) is minimized. This makes it possible to suppress the cost required for the mixing work. The cost may include the price of the closed drug transport system used in the mixing work in addition to the drug price. If the cost is incurred per drug container regardless of whether the drug in the drug container is used up or not, the drug price is calculated by multiplying the unit price of the drug container used (opened) in the mixing work by the number of bottles. If the cost is incurred according to the amount of drug actually consumed (collected or discarded) from the drug in the drug container, the drug price is calculated by multiplying the drug price per unit amount by the amount of drug actually consumed in the mixing work.

The allocation processing unit 211 may also allocate each of the preparation data to the multiple mixing work units so as to minimize the number of times that the drug is collected from the drug container in the mixing work corresponding to the multiple preparation data. For example, consider a case where there are two drug containers containing 0.5 bottles of remaining drug, and a mixing work using 0.9 bottles of the same type of drug is performed. In this case, if the remaining drug is used, two collection operations are required, but if a new drug container is used, only one collection operation is required. In such a case, the allocation processing unit 211 may determine the allocation destination of the preparation data corresponding to the mixing work, assuming that the remaining drug is not used in the mixing work. This minimizes the number of times that the drug is collected from the drug container, and therefore it is possible to suppress a decrease in the efficiency of the mixing work caused by the use of the remaining drug.

The allocation processing unit 211 may execute a grouping process (S131 in FIG. 9), a first allocation process (S132 in FIG. 9), and a second allocation process (S133 in FIG. 9). In the grouping process, one or more preparation data corresponding to a mixing operation that generates the remaining drug and one or more preparation data corresponding to a mixing operation that uses the remaining drug are grouped into one preparation data group. In the first allocation process, the preparation data belonging to the preparation data group is allocated to the multiple mixing operation units on a preparation data group basis. In the second allocation process, the preparation data that does not belong to the preparation data group after the first allocation process is allocated to the multiple mixing operation units.

The allocation processing unit 211 may preferentially allocate to the automatic mixing device 5 preparation data that matches the automatic operation conditions indicating the conditions for allocation to the automatic mixing device 5. For example, the allocation processing unit 211 may preferentially allocate to the automatic mixing device 5 preparation data corresponding to a mixing operation that requires a long working time as an example of the automatic operation conditions. The allocation processing unit 211 may preferentially allocate to the automatic mixing device 5 preparation data corresponding to a mixing operation that requires a large number of times to collect medicine from a medicine container as an example of the automatic operation conditions. The allocation processing unit 211 may preferentially allocate to the automatic mixing device 5 preparation data corresponding to a mixing operation that uses a remaining medicine generated in a preceding mixing operation as an example of the automatic operation conditions. The allocation processing unit 211 may preferentially allocate to the automatic mixing device 5 preparation data corresponding to a mixing operation that uses a powdered medicine (i.e., a mixing operation that requires a stirring operation) as an example of the automatic operation conditions. Furthermore, the allocation processing unit 211 may preferentially allocate preparation data corresponding to a mixing operation using a drug with a high drug price to the automatic mixing device 5 as an example of the automatic operation condition. Furthermore, the allocation processing unit 211 may preferentially allocate preparation data corresponding to a mixing operation using a drug such as some anticancer drugs that have a high risk of exposure to the automatic mixing device 5 as an example of the automatic operation condition.

The allocation processing unit 211 may preferentially allocate to the safety cabinet 100 preparation data that matches a manual work condition indicating a condition for allocation to the safety cabinet 100. For example, the allocation processing unit 211 may preferentially allocate to the safety cabinet 100 preparation data corresponding to a mixing work in which the work time is short, as an example of the manual work condition. The allocation processing unit 211 may preferentially allocate to the safety cabinet 100 preparation data corresponding to a mixing work in which the number of times a drug is taken from a drug container is small, as an example of the manual work condition. The allocation processing unit 211 may preferentially allocate to the safety cabinet 100 preparation data corresponding to a mixing work in which the residual drug generated in a preceding mixing work is not used, as an example of the manual work condition. The allocation processing unit 211 may preferentially allocate to the safety cabinet 100 preparation data corresponding to a mixing work in which the residual drug generated in a preceding mixing work is not used, as an example of the manual work condition. The allocation processing unit 211 may preferentially allocate to the safety cabinet 100 preparation data corresponding to a mixing work in which a powdered drug is not used (i.e., a mixing work that does not require a stirring work), as an example of the manual work condition. Furthermore, the allocation processing unit 211 may preferentially allocate preparation data corresponding to a mixing operation using a drug with a low drug price to the safety cabinet 100 as an example of the manual work condition. Furthermore, the allocation processing unit 211 may preferentially allocate preparation data corresponding to a mixing operation using a drug with a low risk of exposure to the safety cabinet 100 as an example of the manual work condition.

The presentation processing unit 212 presents information regarding the results of allocation by the allocation processing unit 211. For example, the presentation processing unit 212 displays a list of the preparation data allocated to each of the three mixing work units, as in the allocation screen P1 shown in FIG. 11. The presentation processing unit 212 may be capable of printing out the same content as that displayed on the allocation screen P1 using a printing device or the like connected to the communication network N1.

The presentation processing unit 212 may present the preparation data allocated by the allocation processing unit 211 in such a way that the preparation data corresponding to the mixing work that generates residual medicine and the preparation data corresponding to the mixing work that does not generate residual medicine can be distinguished from each other. This makes it easy to distinguish, for example, preparation data corresponding to the mixing work that does not generate residual medicine (i.e., preparation data that does not affect the amount of residual medicine remaining even if the allocation destination is changed to another mixing work unit) when the user changes the allocation destination of the preparation data allocated by the allocation processing unit 211 to another mixing work unit.

The presentation processing unit 212 may present the preparation data allocated by the allocation processing unit 211 in such a way that the preparation data corresponding to the mixing work using the remaining drug generated in the preceding mixing work and the preparation data corresponding to the mixing work not using the remaining drug generated in the preceding mixing work can be distinguished from each other. This allows the worker (pharmacist) performing the mixing work to easily confirm whether or not the remaining drug should be used.

The presentation processing unit 212 may also present the difference between the total amount of medicine required if the remaining medicine is used according to the allocation result by the allocation processing unit 211 and the total amount of medicine required if the remaining medicine is not used.

The presentation processing unit 212 may also present an amount corresponding to the remaining medicine that will ultimately be wasted if a mixed injection operation corresponding to the multiple preparation data is performed according to the allocation result by the allocation processing unit 211.

The remaining amount calculation processing unit 213 calculates the remaining amount of the remaining drug generated in the mixing operation corresponding to the preparation data based on the dosage of the drug indicated in the preparation data and the preset amount of the drug container in which the drug is contained. For example, if the dosage of the drug indicated in the preparation data is 90 mg and the preset amount of the drug container in which the drug is contained is 100 mg, the remaining amount of the remaining drug calculated by the remaining amount calculation processing unit 213 is 10 mg. Also, for example, if the dosage of the drug indicated in the preparation data is 3800 mg and the preset amount of the drug container in which the drug is contained is 1000 mg, the remaining amount of the remaining drug calculated by the remaining amount calculation processing unit 213 is 200 mg.

The remaining amount management processing unit 214 manages the type and amount of remaining medicine remaining in one or more medicine containers in each of the mixed injection work units based on the calculation result of the remaining amount calculation processing unit 213. The remaining amount management processing unit 214 can receive remaining medicine management information (described below) from each of the mixed injection support devices 4 and manage the type and amount of remaining medicine in the entire mixed injection management system 1 based on the remaining medicine management information.

The presentation processing unit 212 is capable of presenting the current remaining amount of each drug based on the information on the type and remaining amount of the remaining drug managed by the remaining amount management processing unit 214 (see FIG. 13).

Below, an example of the procedure of the mixed injection management process executed by the control unit 21 of the mixed injection management device 2 will be described with reference to Figures 8 and 9. Here, steps S11, S12, S13, etc. shown in Figures 8 and 9 indicate identification codes of the procedure of the mixed injection management process executed by the control unit 21.

In addition, another embodiment is also conceivable in which the mixed injection management device 2 has multiple control units, and the mixed injection management process is executed by the multiple control units. Furthermore, a part or all of the process executed by the control unit 21 may be executed by an electronic circuit such as an ASIC or DSP. Also, a part or all of the process executed by the control unit 21 may be executed by a control unit of another device (for example, the control unit 41 of the mixed injection support device 4, the first control unit 52 of the automatic mixed injection device 5, the second control unit 53 of the automatic mixed injection device 5, etc.).

[Mixed injection management processing]
<Step S11>
8, the control unit 21 displays a distribution screen P1 as shown in FIG. 10 on the display unit 24 of the mixed injection management device 2 in response to a user operation on the operation unit 25 of the mixed injection management device 2. The control unit 21 may display the distribution screen P1 on the display unit 34 of the client terminal 3 in response to a user operation on the operation unit 35 of the client terminal 3.

As shown in FIG. 10, the allocation screen P1 includes a prescription selection area A11, a condition setting area A12, multiple mixed injection work area A13, a drug price display area A14, and a CSTD price display area A15.

The prescription selection area A11 is an area for selecting preparation data (prescription) to be allocated in the allocation process (S13) described later. The condition setting area A12 is an area for setting allocation conditions in the allocation process. The mixed injection work area A13 is an area provided for each mixed injection work area to which the data is allocated in the allocation process. The drug price display area A14 is an area for displaying the difference between the total drug price required when the remaining drugs are used according to the allocation result in the allocation process and the total drug price required when the remaining drugs are not used. The CSTD price display area A15 is an area for displaying the number and price of closed system drug transfer systems (CSTDs) required when the mixed injection work is performed according to the allocation result in the allocation process.

The user can select the preparation data to be the target of the allocation process by performing an operation on the prescription selection area A11 through the operation unit 25. For example, when the user wants to execute the allocation process for the preparation data corresponding to the mixing work of medicines to be administered to an inpatient and an outpatient on the next day, the user selects the next day's date while checking both the check box corresponding to the inpatient and the check box corresponding to the outpatient. As a result, the corresponding preparation data is displayed in a list in the prescription selection area A11. Specifically, the preparation data image D11 corresponding to the corresponding preparation data is displayed in the prescription selection area A11. That is, the control unit 21 extracts one or more of the preparation data from the multiple preparation data stored in the storage unit 22 in response to the user's operation on the prescription selection area A11. Then, the control unit 21 displays the preparation data image D11 corresponding to the extracted preparation data in the prescription selection area A11.

The preparation data image D11 displays, for example, a serial number, information indicating the corresponding patient and regimen, the name of the drug used, and the dosage of the drug. Note that, when multiple types of drugs (e.g., multiple types of anticancer drugs) are collected in a mixing operation corresponding to one preparation data, the preparation data image D11 may display the names of each of the multiple types of drugs.

When any of the preparation data images D11 displayed in the prescription selection area A11 is operated (e.g., clicked) by the user, the control unit 21 changes the display mode of the operated preparation data image D11. For example, the control unit 21 changes the background color of the preparation data image D11 from white, which indicates the non-selected state, to green, which indicates the selected state. Note that the method of changing the display mode by the control unit 21 described here is merely an example. Instead of changing the background color, the control unit 21 may, for example, change the color of the characters, change the thickness of the characters or lines, flash the characters or images in different patterns, display the characters inverted, or add specific characters, symbols, images, etc. The same applies to the following description.

The allocation screen P1 includes a select all key K12 and a cancel all key K13. When the select all key K12 is operated, the control unit 21 changes all of the preparation data images D11 displayed in the prescription selection area A11 to a selected state. When the cancel all key K13 is operated, the control unit 21 changes all of the preparation data images D11 displayed in the prescription selection area A11 to a non-selected state.

The user can set the allocation conditions for the allocation process by operating the condition setting area A12 through the operation unit 25. In the example shown in FIG. 10, the condition setting area A12 displays three setting items: "Safety Cabinet," "Chemoro," and "Remaining Drug Use."

The "Safety Cabinet" and "Chemoro" items are items for setting the allocation destination in the allocation process. For example, as shown in FIG. 10, when "Safety Cabinet" is set to "2 units" and "Chemoro" is set to "Yes", the allocation screen P1 displays three co-infusion work areas A13 corresponding to two safety cabinets 100 and one automatic co-infusion device 5.

The "use of remaining medicine" item is an item for setting whether or not to use the remaining medicine generated in the preceding mixing work in the mixing work corresponding to the preparation data to be allocated in the allocation process. For example, if the remaining medicine is used in the busy morning hours, the mixing work will take more time, and there may be a shortage of manpower. Therefore, it is conceivable that the remaining medicine generated in the preceding mixing work is left unused in the mixing work performed in the morning, and the remaining medicine generated in the preceding mixing work (including the remaining medicine generated in the mixing work performed in the morning) is used in the mixing work performed in the afternoon. In this case, first, with "use of remaining medicine" set to "no," the allocation process is executed with the preparation data corresponding to the mixing work performed in the morning as the allocation target, and then, with "use of remaining medicine" set to "yes," the allocation process is executed with the preparation data corresponding to the mixing work performed in the afternoon as the allocation target.

<Step S12>
In step S12, the control unit 21 judges whether or not a predetermined sorting start operation has been performed. For example, the control unit 21 judges that the sorting start operation has been performed when a sorting start key K11 included in the sorting screen P1 has been operated. If the control unit 21 judges that the sorting start operation has been performed (S12: Yes), the control unit 21 shifts the process to step S13, and if the control unit 21 judges that the sorting start operation has not been performed (S12: No), the control unit 21 shifts the process to step S15.

<Step S13>
In step S13, the control unit 21 performs the allocation process based on the allocation conditions set in the condition setting area A12, with the preparation data selected in the prescription selection area A11 (i.e., the preparation data corresponding to the preparation data image D11 in the selected state) as the allocation target. An example of the allocation process will be described below with reference to Fig. 9. Note that, here, the case where "use of remaining medicine" is set to "Yes" in the allocation conditions will be described.

<Step S131>
In step S131 shown in Fig. 9, the control unit 21 performs a grouping process. Specifically, the control unit 21 groups, among the preparation data to be allocated, one or more preparation data corresponding to a mixing operation that generates a remaining drug and one or more preparation data corresponding to a mixing operation that uses the remaining drug into one preparation data group.

In the grouping process, the control unit 21 first calculates, for each preparation data to be allocated, the remaining amount of the remaining medicine that occurs when the remaining medicine is not used in the mixing operation corresponding to the preparation data. Specifically, the control unit 21 calculates the remaining amount based on the dose of the medicine indicated in the preparation data and the preset amount of the medicine container used in the mixing operation. For example, if the dose of the medicine indicated in the preparation data is 140 mg and the preset amount of the medicine container containing the medicine is 100 mg, all the medicine is collected from the first medicine container (full amount collected), and 40 mg of the medicine is collected from the second medicine container (fractional amount collected). Therefore, the remaining amount of the remaining medicine calculated by the remaining amount calculation processing unit 213 is 60 mg. In addition, if the dosage of the drug indicated in the preparation data is an integer multiple of the preset amount of the drug container used in the mixing operation, only the entire amount is collected (i.e., the entire preset amount of drug is collected from the drug container), and no fractional amount is collected (i.e., only an amount of drug less than the preset amount is collected from the drug container), so no residual drug is generated in the mixing operation corresponding to the preparation data.

The control unit 21 then determines, for each of the preparation data corresponding to a mixing task that generates residual chemicals, whether or not there is a preceding mixing task that generates the same type of residual chemicals (i.e., a mixing task performed earlier). In this way, the control unit 21 correlates the preparation data corresponding to the mixing task that generates residual chemicals with the preparation data corresponding to the mixing task that can use the residual chemicals, and finally groups the multiple preparation data that are correlated with each other into one preparation data group.

As an example, the following describes a specific processing method when grouping processing is performed on the following preparation data. Note that the same type of medicine is used in the mixing work corresponding to the following preparation data. Also, it is assumed that a medicine container with the above-mentioned default amount of 100 mg is used in the mixing work corresponding to the following preparation data. Also, it is assumed that the following preparation data is arranged in order of the earliest time the mixing work was performed.

(Preparation Data A) Dose 140 mg
(Preparation Data B) Dose 200 mg
(Preparation Data C) Dose 160 mg
(Preparation Data D) Dose 210 mg
(Preparation Data E) Dose 150 mg
(Preparation Data F) Dose 100 mg
(Preparation Data G) Dose 130 mg

First, the control unit 21 calculates the remaining amount of remaining medicine that will occur in the mixed injection work corresponding to each of the preparation data when the remaining medicine is not used. The calculation result is as follows.

(Preparation data A) Remaining amount: 60 mg (Number of drug containers used: 2)
(Preparation data B) Remaining amount 0 mg (Number of drug containers used: 2)
(Preparation Data C) Remaining amount: 40 mg (Number of drug containers used: 2)
(Preparation data D) Remaining amount: 90 mg (Number of drug containers used: 3)
(Preparation Data E) Remaining amount: 50 mg (Number of drug containers used: 2)
(Preparation data F) Remaining amount 0 mg (Number of drug containers used: 1)
(Preparation data G) Remaining amount 70 mg (Number of drug containers used: 2)

Next, the control unit 21 judges whether or not there is a preceding mixing operation (i.e., a mixing operation performed earlier) that generates the same type of remaining drug for each of the preparation data (here, preparation data A, C, D, E, and G) corresponding to the mixing operation that generates the remaining drug. As a result, it is found that the mixing operation corresponding to preparation data C may be able to use the remaining drug generated in the mixing operation corresponding to preparation data A. It is also found that the mixing operation corresponding to preparation data D may be able to use the remaining drug generated in the mixing operation corresponding to preparation data A and C. It is also found that the mixing operation corresponding to preparation data E may be able to use the remaining drug generated in the mixing operation corresponding to preparation data A, C, and D. It is also found that the mixing operation corresponding to preparation data G may be able to use the remaining drug generated in the mixing operation corresponding to preparation data A, C, D, and E.

Now, looking at preparation data C, the mixing operation (dose 160 mg) corresponding to preparation data C can use the remaining medicine (60 mg remaining) generated in the mixing operation corresponding to preparation data A. Therefore, the control unit 21 correlates preparation data A and preparation data C. If the remaining medicine is used, no remaining medicine is generated in the mixing operation corresponding to preparation data C. In other words, when the mixing operation corresponding to preparation data C is completed, the remaining amount of the remaining medicine becomes 0 mg. Therefore, the control unit 21 groups dispensing data A and dispensing data C into one preparation data group. The total number of medicine containers required for the mixing operation corresponding to the preparation data group is three, which is one less than the total number (four) required when the remaining medicine is not used.

Next, looking at preparation data D, when the mixing operation corresponding to preparation data D begins, the remaining amount of the remaining medicine is 0 mg. Therefore, the remaining medicine cannot be used in the mixing operation corresponding to preparation data D. Then, when the mixing operation corresponding to preparation data D is completed, the remaining amount of the remaining medicine is 90 mg.

Next, looking at preparation data E, when the co-injection work corresponding to preparation data E is started, the remaining amount of the remaining medicine is 90 mg. Therefore, in the co-injection work corresponding to preparation data E, the remaining medicine (90 mg) generated in the co-injection work corresponding to preparation data D can be used. Therefore, the control unit 21 correlates preparation data D and preparation data E. Then, when the co-injection work corresponding to preparation data E is completed, the remaining amount of the remaining medicine is 40 mg.

Next, looking at preparation data G, when the mixed injection work corresponding to preparation data G is started, the remaining amount of the remaining medicine is 40 mg. Therefore, in the mixed injection work corresponding to preparation data G, the remaining medicine (40 mg) generated in the mixed injection work corresponding to preparation data E can be used. Therefore, the control unit 21 correlates the preparation data E and the preparation data G. Then, when the mixed injection work corresponding to preparation data G is completed, the remaining amount of the remaining medicine is 10 mg. This remaining medicine will not be used in the subsequent mixed injection work. Therefore, the control unit 21 groups the correlated preparation data D, preparation data E, and preparation data G into one preparation data group. The total number of medicine containers required for the mixed injection work corresponding to the preparation data group is 5, which is 2 less than the total number of use (7) when the remaining medicine is not used.

In this way, two preparation data groups are generated from the above preparation data A to G.

<Step S132>
In step S132, the control unit 21 performs a first allocation process. Specifically, the control unit 21 allocates the preparation data belonging to the preparation data group to the multiple mixed injection work units in units of the preparation data group. The allocation destination of the preparation data belonging to the preparation data group may be determined, for example, so that the same number of preparation data is allocated to the multiple mixed injection work units as much as possible, or may be determined based on the allocation condition. For example, when the allocation condition is that the preparation data corresponding to the mixed injection work using the remaining medicine is preferentially allocated to a specific mixed injection work unit, the control unit 21 preferentially allocates the preparation data belonging to each of the preparation data groups to the specific mixed injection work unit.

<Step S133>
In step S133, the control unit 21 performs a second allocation process. Specifically, the control unit 21 allocates preparation data that does not belong to the preparation data group to the multiple mixed injection work units. The allocation destination of the preparation data that does not belong to the preparation data group may be determined, for example, so that the same number of preparation data is allocated to the multiple mixed injection work units as much as possible, or may be determined based on the allocation condition.

In this way, the preparation data selected in the prescription selection area A11 (i.e., the preparation data corresponding to the preparation data image D11 in the selected state) is distributed to multiple mixed injection work units based on the distribution conditions set in the condition setting area A12. When the distribution process is completed, the control unit 21 transitions the process to step S14 in FIG. 8.

<Step S14>
In step S14, the control unit 21 displays the allocation result by the allocation process executed in step S13 on the display unit 24. Specifically, as shown in FIG. 11, the control unit 21 displays a preparation data image D12 corresponding to the preparation data allocated to the mixed injection work unit in the corresponding mixed injection work unit area A13 for each mixed injection work unit to which the data is allocated in the allocation process. In the example shown in FIG. 11, of the 38 preparation data selected in the prescription selection area A11, 16 preparation data are allocated to "safety cabinet 1", another 16 preparation data are allocated to "safety cabinet 2", and the remaining 6 preparation data are allocated to "chemoro".

The preparation data image D12 displays, for example, the administration time of the corresponding drug, information indicating the corresponding patient and regimen, the name of the drug used, and the dose of the drug. In each of the mixed injection work areas A13, the preparation data images D12 are displayed, for example, arranged in order according to the administration time.

The control unit 21 displays, among the preparation data images D12 displayed in the mixing work area A13, the preparation data images D12 corresponding to mixing work using residual medicine generated in the preceding mixing work, with a background color of, for example, yellow. This allows the worker (pharmacist) performing the mixing work to easily understand which mixing work requires the use of residual medicine. The control unit 21 displays, for example, the background color of the preparation data images D12 corresponding to mixing work that does not use residual medicine generated in the preceding mixing work and generates residual medicine, with a background color of, for example, white. The control unit 21 displays, for example, the background color of the preparation data images D12 corresponding to mixing work that does not use residual medicine generated in the preceding mixing work and generates no residual medicine, with a background color of, for example, gray.

The control unit 21 also displays, as an example of information related to the allocation result of the allocation process, in the drug price display area A14, the difference between the total drug price required when the remaining drug is used according to the allocation result of the allocation process and the total drug price required when the remaining drug is not used. The control unit 21 also displays the difference calculated for each mixing work unit at the bottom of each mixing work unit area A13.

The control unit 21 also displays, in the CSTD amount display area A15, the number and amount of closed system drug transfer systems (CSTDs) required when a mixing operation is performed according to the allocation result in the allocation process, as an example of information related to the allocation result of the allocation process. The control unit 21 also displays, at the bottom of each mixing operation area A13, the number and amount of the closed system drug transfer systems (CSTDs) calculated for each mixing operation unit.

<Step S15>
In step S15, the control unit 21 judges whether or not a predetermined display switching operation has been performed. For example, the control unit 21 judges that the display switching operation has been performed when a display switching key K14 included in the sorting screen P1 has been operated. If the control unit 21 judges that the display switching operation has been performed (S15: Yes), the control unit 21 shifts the process to step S16, and if the control unit 21 judges that the display switching operation has not been performed (S15: No), the control unit 21 shifts the process to step S17.

<Step S16>
In step S16, the control unit 21 updates the amount information displayed in the drug price display area A14. Specifically, the control unit 21 displays, in the drug price display area A14, an amount corresponding to the remaining drug that will ultimately be wasted if a mixed injection operation is performed according to the allocation result in the allocation process (hereinafter referred to as the remaining drug amount), as an example of information related to the allocation result by the allocation process. If the display switch key K14 is operated again while the remaining drug amount is displayed in the drug price display area A14, the control unit 21 displays the difference again in the drug price display area A14.

<Step S17>
In step S17, the control unit 21 judges whether a predetermined prepared operation has been performed. For example, when the prepared key K16 included in the sorting screen P1 is operated while one or more of the prepared data images D12 are selected, the control unit 21 judges that the prepared operation has been performed. The prepared operation is performed, for example, whenever a mixed injection operation corresponding to the prepared data image D12 is completed. When the control unit 21 judges that the prepared operation has been performed (S17: Yes), the control unit 21 shifts the process to step S18, and when the control unit 21 judges that the display switching operation has not been performed (S17: No), the control unit 21 shifts the process to step S19.

<Step S18>
In step S18, the control unit 21 updates the remaining medicine information. The remaining medicine information is information about the remaining medicine remaining in the multiple mixed injection work units, and is stored in, for example, the memory unit 22. The remaining medicine information includes various information such as the type of the remaining medicine, the remaining amount, the opening date and time, and the location (mixed injection work unit). The control unit 21 calculates the remaining amount of the remaining medicine generated in the mixed injection work corresponding to the preparation data image D12 selected when the prepared operation was performed, for example, based on the preparation data corresponding to the preparation data image D12 and the current remaining medicine information. Then, the control unit 21 updates the remaining medicine information based on the calculation result.

The control unit 21 changes the outline of the preparation data image D12 that was selected when the prepared operation was performed to, for example, a thick red line. This allows the user to easily distinguish between the preparation data image D12 for which the mixing operation has been completed and the preparation data image D12 for which the mixing operation has not been completed. The example in FIG. 12 shows a state in which all mixing operations corresponding to preparation data with administration times earlier than 12 o'clock have been completed.

The control unit 21 may also print the remaining medicine authentication label to be affixed to a medicine container in which remaining medicine has occurred. This allows an operator to easily grasp the contents of the remaining medicine in the medicine container by affixing the remaining medicine authentication label to the medicine container or the location where the medicine container is placed. Note that printing of the remaining medicine authentication label is not limited to step S18, and may be performed at a preset timing, or may be performed at any timing in response to a print request operation by the operator.

<Step S19>
In step S19, the control unit 21 judges whether or not a predetermined remaining medicine check operation has been performed. For example, the control unit 21 judges that the remaining medicine check operation has been performed when the remaining medicine check key K15 included in the allocation screen P1 has been operated. If the control unit 21 judges that the remaining medicine check operation has been performed (S19: Yes), the control unit 21 shifts the process to step S20, and if the control unit 21 judges that the remaining medicine check operation has not been performed (S19: No), the control unit 21 shifts the process to step S21.

<Step S20>
In step S20, the control unit 21 displays a remaining medicine screen P2 as shown in Fig. 13 on the display unit 24 based on the remaining medicine information. The remaining medicine screen P2 includes an entire display area A21 and a plurality of mixed injection work areas A22.

The overall display area A21 is an area for displaying the total remaining amount of medicine remaining in each of the mixing work units, calculated by adding up the remaining amount by type of medicine. In the overall display area A21, information such as the name of the medicine (e.g., "One Taxotere", "Bitterza", etc.), mg value, mL value, and number of bottles, for each type of medicine, is displayed. The mg value and the mL value indicate the total remaining amount of the medicine. The number indicates the total number of medicine containers in which the medicine remains. For example, if 20 mg of medicine A remains in a medicine container with a preset amount of 100 mg, and 110 mg of medicine A remains in a medicine container with a preset amount of 200 mg, the mg value for medicine A will be 130, and the number will be 2.

The mixing work area A22 is an area for displaying information about the remaining medicines remaining in the corresponding mixing work area. The mixing work area A22 includes an upper area A221 and a lower area A222.

The upper area A221 of the mixing work area A22 is an area for displaying information about the remaining medicine remaining in the corresponding mixing work area for each medicine container of the same type. For each medicine container of the same type, information such as the medicine container name (e.g., "One Taxotere 20 mg", "Bitaza 100 mg", etc.), mg value, mL value, and number of bottles is displayed in the upper area A221. The mg value and the mL value indicate the total remaining amount of medicine in one or more medicine containers of the same type in the corresponding mixing work area. The number indicates the number of one or more medicine containers of the same type in which the medicine remains.

When the user selects one or more of the drugs displayed in the overall display area A21, the control unit 21 displays only information related to the drug selected by the user in the mixed injection work area A22, as shown in FIG. 14. This allows the user to easily grasp, for example, how many drug containers in which the desired drug remains are located in each mixed injection work area.

When one or more of the drug containers displayed in the upper area A221 are selected by the user, the control unit 21 displays detailed information about the drug container selected by the user in the lower area A222, as shown in FIG. 15. In the lower area A222, information such as a serial number, a remaining amount image, a mg value, a mL value, and a start date and time is displayed for each drug container. The remaining amount image is an image that shows a schematic representation of the remaining amount of drug in the drug container. The mg value and the mL value are numerical values that indicate the remaining amount of drug in the drug container. The start date and time is the date and time when a mixing operation using the drug container was first performed.

Although omitted in the flowchart shown in FIG. 8, when the close key K21 included in the remaining medicine screen P2 is operated, the control unit 21 closes the remaining medicine screen P2 and redisplays the allocation screen P1 on the display unit 24.

<Step S21>
In step S21, the control unit 21 judges whether or not a predetermined ending operation has been performed. For example, the control unit 21 judges that the ending operation has been performed when a close key K18 included in the allocation screen P1 has been operated. Then, when the control unit 21 judges that the ending operation has been performed (S21: Yes), it ends the mixed injection management process, and when the control unit 21 judges that the ending operation has not been performed (S21: No), it returns the process to step S12.

Although omitted in the flowchart shown in FIG. 8, for example, when the clear key K17 included in the sorting screen P1 is operated in the state shown in FIG. 11 or FIG. 12, the control unit 21 returns the sorting screen P1 to the state shown in FIG. 10.

Although omitted in the flowchart shown in FIG. 8, when a statistics key K19 included in the allocation screen P1 is operated, the control unit 21 displays a statistics screen (not shown) on the display unit 24. The statistics screen displays statistical information regarding the co-injection work performed during a specific period (e.g., the past month, the past year, a month specified by the user, etc.).

The statistical screen may display, for example, for each drug container of the same type, the difference between the number of drug containers actually used in the mixing work performed during the specific period and the number of drug containers that would be required if the remaining drug was not used at all. Based on the difference in drug containers, the statistical screen may also display the difference in drug price between the number of drug containers actually used and the number of drug containers that would be required if the remaining drug was not used at all. This makes it easy to confirm the financial effect of using the remaining drug during the specific period. The statistical screen P3 may also display the difference for each doctor who ordered the mixing work. This makes it easy to confirm the financial effect for each doctor.

As described above, in the mixed injection management system 1 according to this embodiment, preparation data corresponding to a mixed injection task that generates residual medicine and preparation data corresponding to a mixed injection task that uses the residual medicine are distributed to the same mixed injection work section. Therefore, residual medicine generated in one mixed injection task can be used in another mixed injection task without taking the medicine container in which the medicine remains outside the mixed injection work section. Therefore, the mixed injection management system 1 according to this embodiment can support efficient use of medicines contained in medicine containers.

The present invention is not limited to anticancer drugs, but is also effective for allocating preparation data for any drug that should be mixed under sterile conditions, particularly when expensive drugs are used in the mixing process.

[Modification]
In another embodiment, the control unit 21 may transmit each of the preparation data to the co-infusion support device 4 or the automatic co-infusion device 5 based on the allocation result by the allocation processing unit 211. For example, the control unit 21 may transmit the preparation data allocated to "safety cabinet 1" to the co-infusion support device 4 corresponding to "safety cabinet 1", transmit the preparation data allocated to "safety cabinet 2" to the co-infusion support device 4 corresponding to "safety cabinet 2", and transmit the preparation data allocated to "chemolo" to the automatic co-infusion device 5. Then, in the co-infusion support device 4, the co-infusion support process may be executed based on the preparation data received from the co-infusion management device 2. In addition, in the automatic co-infusion device 5, the automatic co-infusion process may be executed based on the preparation data received from the co-infusion management device 2.

In addition, in this embodiment, when it is determined in step S17 of FIG. 8 that the prepared operation has been performed, the remaining medicine information is updated in step S18. In other embodiments, however, the remaining medicine information may be updated when a work completion notification signal indicating that the mixing operation has been completed is received from the mixing assistance device 4 or the automatic mixing device 5. The work completion notification signal includes, for example, preparation data identification information for identifying the preparation data corresponding to the completed mixing operation.

In another embodiment, the allocation screen P1 or the remaining medicine screen P2 may be displayed on the operation display unit 42 of the co-infusion support device 4 or the display 541 of the automatic co-infusion device 5. A user operation on the allocation screen P1 or the remaining medicine screen P2 may be performed through the operation display unit 42 of the co-infusion support device 4 or the operation unit 525 of the automatic co-infusion device 5.

In addition, in this embodiment, as described above, the remaining amount calculation processing unit 213 calculates the remaining amount of the remaining drug generated in the mixed injection work corresponding to the preparation data based on the dosage of the drug indicated in the preparation data and the predetermined amount of the drug container in which the drug is contained. However, depending on the type of the drug container, a drug may always be contained in an amount greater than the predetermined amount. For example, a drug container with a predetermined amount of 100 mg may always contain 105 mg of drug. Therefore, when using such a drug container, a function for correcting the predetermined amount may be provided in the mixed injection management system 1 so that the drug contained in the drug container can be used without waste. For example, a correction coefficient (for example, "1.05") for correcting the predetermined amount may be stored in the memory unit 22 or the like for each type of drug container. The correction coefficient may be set or changed according to a user operation. The remaining amount calculation processing unit 213 may correct the predetermined amount of the medicine container containing the medicine by multiplying it by the correction coefficient, and calculate the remaining amount of the medicine remaining in the mixing operation corresponding to the preparation data based on the dose of the medicine indicated in the preparation data and the corrected predetermined amount. When the mixing operation is performed by a robot in the automatic mixing device 5, a more accurate amount of medicine can be collected from the medicine container compared to when the mixing operation is performed by a person in the safety cabinet 100. Therefore, the remaining amount calculation processing unit 213 may change the correction coefficient when calculating the remaining amount of the medicine remaining in the mixing operation performed in the automatic mixing device 5 and when calculating the remaining amount of the medicine remaining in the mixing operation performed in the safety cabinet 100. For example, the remaining amount calculation processing unit 213 may make the correction coefficient smaller in the latter case than in the former case.

In particular, in the case of a mixed injection operation performed in the safety cabinet 100, since the mixed injection operation is performed by a person, an excess amount of medicine may be collected that is greater than the amount that should be collected. If this happens, the actual remaining amount will be less than the remaining amount calculated by the remaining amount calculation processing unit 213. In order to deal with such a situation, the mixed injection management system 1 may be provided with a function for correcting the remaining amount calculated by the remaining amount calculation processing unit 213. For example, the control unit 21 may correct the remaining amount calculated by the remaining amount calculation processing unit 213 by multiplying it by a predetermined correction coefficient that is less than 1. The correction coefficient may be set or changed in response to a user operation.

In another embodiment, the control unit 21 may present information on whether the remaining medicine generated in each of the mixing operations should be discarded or left, based on the allocation result in the allocation process. For example, the control unit 21 judges whether the remaining medicine generated in each of the mixing operations is likely to be used in the subsequent mixing operations. For example, the control unit 21 may judge that the remaining medicine is unlikely to be used in the subsequent mixing operations when there is no subsequent mixing operations that use the same type of medicine as the remaining medicine. Then, the control unit 21 may change the display mode of the preparation data image D12 corresponding to the mixing operations in which the remaining medicine is generated, which is unlikely to be used in the subsequent mixing operations, to a specific display mode (for example, adding a character, symbol, or image indicating that the remaining medicine should be discarded). This allows the operator (pharmacist) of the mixing operation to immediately discard the remaining medicine that is unlikely to be used in the subsequent mixing operation. This makes it possible to prevent unnecessary remaining medicine from being stored in the safety cabinet 100 and to prevent the occurrence of a mix-up of medicine containers.

In another embodiment, the control unit 21 may display each of the preparation data images D12 displayed in the mixed injection work area A13 of the sorting screen P1 in a different display mode for each preparation data group to which the corresponding preparation data belongs. For example, the control unit 21 may add a number, symbol, or image to each preparation data image D12 for identifying the preparation data group to which each preparation data image D12 belongs.

In another embodiment, the preparation data automatically allocated in the allocation process may be reassigned to another mixed injection work section in response to a user operation. For example, the control unit 21 may change the allocation destination of the preparation data corresponding to the preparation data image D12 in response to a drag-and-drop operation on the preparation data image D12 displayed in the mixed injection work section area A13 of the allocation screen P1. In addition, when the preparation data corresponding to the preparation data image D12 belongs to any of the preparation data groups, the allocation destination of multiple preparation data belonging to the preparation data group may be changed collectively to the same mixed injection work section in response to the drag-and-drop operation.

In another embodiment, the remaining medicine information may be configured to be changeable by the user as needed. For example, the control unit 21 may update information such as the remaining amount and location of the remaining medicine contained in the remaining medicine information in response to a user operation on the remaining medicine screen P2. This allows the user to update the remaining medicine information to correct information as needed, for example, when medicine is spilled during the mixing operation, or when the mixing operation is performed in a mixing operation unit other than the mixing operation unit assigned in the allocation process.

In another embodiment, the destination mixing work area in the sorting process may be a safety cabinet that is not provided with a mixing support device 4.

In another embodiment, the destination mixing work area in the sorting process may be only the mixing work area where mixing work is performed by a person (i.e., the safety cabinet 100).

In another embodiment, the destination mixing work unit in the allocation process may be only the mixing work unit where the mixing work is performed by a robot (i.e., the automatic mixing device 5).

In addition, in this embodiment, the case where there are multiple mixing work units to which the allocation process is to be performed has been described, but it is also possible that there is only one mixing work unit to which the allocation process is to be performed. In this case, all preparation data selected as the allocation target in the allocation process is assigned to one mixing work unit, and the drug price display area A14 displays the difference between the total drug price required when the remaining drug is used and the total drug price required when the remaining drug is not used. The difference changes depending on the setting content of the setting item "remaining drug use" in the condition setting area A12. For example, in the mixing work performed in the morning, the remaining drug generated in the preceding mixing work is left unused, and in the mixing work performed in the afternoon, the remaining drug generated in the preceding mixing work (including the remaining drug generated in the mixing work performed in the morning) is used. In this case, first, the first allocation process is performed with the preparation data corresponding to the mixed injection work performed in the morning set to "no use" and then the second allocation process is performed with the preparation data corresponding to the mixed injection work performed in the afternoon set to "yes". In this case, if the mixed injection work using the same type of drug is concentrated in the morning, the remaining drug generated in the morning cannot be used up in the mixed injection work performed in the afternoon, and most of the remaining drug will be wasted. Therefore, the user may limit the preparation data for which "remaining drug use" is set to "no" to the preparation data administered between 9:00 and 10:00, for example, and re-execute the allocation process to check the amount displayed in the drug price display area A14. If the remaining drug generated in the mixed injection work corresponding to the preparation data administered between 9:00 and 10:00 is used in the mixed injection work corresponding to the preparation data administered between 11:00 and 12:00, the remaining drug that will ultimately be wasted will be reduced, and the amount displayed in the drug price display area A14 will change. In this way, the mixed injection management system 1 according to this embodiment can support efficient use of medicines contained in medicine containers even when there is only one mixed injection work unit to which the allocation process is assigned.

[Other embodiments]
As described above, after the mixed injection work based on the preparation data input to the mixed injection support device 4 is performed, if a drug remains in the drug container used in the mixed injection work, the drug container may be stored in the work chamber 101 until it is used next. Hereinafter, a case will be described in which the mixed injection support device 4 includes a drug storage unit 300 on which a plurality of drug containers can be placed. Note that the same reference numerals are used for components that are the same as those described in the embodiment of the mixed injection support device 4. In addition, in the mixed injection management system 1 including the mixed injection support device 4 according to this embodiment, the mixed injection management process (see FIG. 8) does not need to be performed by the mixed injection management device 2.

As shown in FIG. 16, the medicine storage unit 300 is communicably connected to the control unit 41 of the co-infusion support device 4. For example, the medicine storage unit 300 is connected to the co-infusion support device 4 so as to be capable of short-range wireless communication, or is connected to the co-infusion support device 4 via a communication cable. The co-infusion support device 4 may also include a plurality of the medicine storage units 300, each of which may be communicably connected to the co-infusion support device 4. In this case, the co-infusion support device 4 can identify each of the medicine storage units 300 by a unit number that is preset for each medicine storage unit 300. The medicine storage unit 300 is supplied with power from the co-infusion support device 4 or a commercial AC power source.

As shown in FIG. 17, the medicine storage unit 300 is placed in a position within the safety cabinet 100 that is accessible to an operator who performs the co-injection operation in the safety cabinet 100. Note that FIG. 17 shows a state in which a plurality of medicine containers 400 are placed on the medicine storage unit 300. The medicine storage unit 300 has a circular shape in a plan view, and the size of the medicine storage unit 300 is, for example, an outer diameter of 300 mm and a height of 190 mm.

18 and 19, the medicine storage unit 300 includes an upper stage mounting section 310, a lower stage mounting section 320, and a pivot support section 330. Each of the upper stage mounting section 310 and the lower stage mounting section 320 includes a plurality of medicine mounting sections 301 on which medicine containers can be mounted. As shown in FIG. 19, the medicine mounting sections 301 are arranged in a ring shape in each of the upper stage mounting section 310 and the lower stage mounting section 320. The medicine mounting section 301 has a recess on which the medicine container is mounted, and the recess is inclined outward from the bottom to the top. That is, the medicine mounting section 301 has a shape that allows the medicine container to be inclined outward when the medicine container is mounted. This makes it easy to mount and remove the medicine container on the medicine mounting section 301. The bottom surface of the recess of the medicine placement section 301 is, for example, a plane parallel to the horizontal plane or a plane perpendicular to the inclination of the recess.

The rotation support part 330 supports the upper stage placement part 310 and the lower stage placement part 320 so that they can rotate as a unit. Specifically, in this embodiment, the upper stage placement part 310 and the lower stage placement part 320 in the medicine storage unit 300 can rotate within a preset range of 360 degrees or less. This allows an operator to rotate the upper stage placement part 310 and the lower stage placement part 320 to access any of the medicine placement parts 301. Note that the upper stage placement part 310 and the lower stage placement part 320 may each be supported so that they can rotate individually. It is also possible that the rotation support part 330 includes a drive part such as a stepping motor or a DC motor that rotates the upper stage placement part 310 and the lower stage placement part 320. In this case, the control unit 41 can control the drive unit of the rotation support unit 330 in response to a user operation to rotate the upper placement unit 310 and the lower placement unit 320. In addition, if the rotation positions of the upper placement unit 310 and the lower placement unit 320 of the medicine storage unit 300 can be detected, the control unit 41 can rotate the upper placement unit 310 and the lower placement unit 320 to a position close to the operator when placing the medicine container on the medicine placement unit 301 or removing it. Note that the medicine storage unit 300 may not include the rotation support unit 330 and may not be circular in plan view. For example, the medicine storage unit 300 may be configured to include a plurality of the medicine placement units 301 arranged side by side along a straight line, an arc, or an L-shape.

Each of the medicine placement units 301 is provided with a placement detection unit 311 and a status display unit 312. Each of the medicine placement units 301 is assigned a shelf number for identifying the medicine placement unit 301, and the control unit 41 can identify each of the medicine placement units 301.

Each of the placement detection units 311 is an optical sensor, a mechanical sensor, or the like used to detect whether or not the drug container is placed on the drug placement unit 301 corresponding to the placement detection unit 311. The detection result by each of the placement detection units 311 is input to the control unit 41 of the co-infusion support device 4.

Each of the status display units 312 is used to indicate the state of the medicine placement unit 301 corresponding to that status display unit 312. The display contents of each of the status display units 312 are controlled by the control unit 41 of the co-infusion support device 4. Specifically, each of the status display units 312 includes a light-emitting element (LED) capable of emitting light in multiple colors, and indicates the state of the medicine placement unit 301 by the light-emitting color and light-emitting mode of the light-emitting element. In this embodiment, an example will be described in which the status display unit 312 includes an LED capable of emitting light in two colors, red and blue.

The status display unit 312 is disposed inside the upper placement unit 310 and the lower placement unit 320, and the surface 310A of the upper placement unit 310 and the surface 320A of the lower placement unit 320 are formed of a transparent, semi-transparent, or highly transmittance material. As a result, the light of the status display unit 312 passes through the surface 310A of the upper placement unit 310 or the surface 320A of the lower placement unit 320 and can be seen from the outside. The status display unit 312 may be exposed to the surface 310A of the upper placement unit 310 and the surface 320A of the lower placement unit 320. Furthermore, the status display unit 312 may be an annular light-emitting unit provided along the outer periphery of the medicine placement unit 301.

Specifically, the storage unit 413 stores correspondence information indicating the correspondence between the light emission color and light emission mode of the status display unit 312 and the state of the medicine placement unit 301, and the control unit 41 controls the status display unit 312 based on the correspondence information. For example, the control unit 41 turns off the status display unit 312 when the medicine container is not placed on the medicine placement unit 301. In addition, the control unit 41 turns on the status display unit 312 in blue when a valid medicine container whose expiration date has not yet arrived is placed on the medicine placement unit 301, and turns on the status display unit 312 in red when an invalid medicine container whose expiration date has arrived is placed on the medicine placement unit 301. The expiration date is, for example, the date by which the medicine in the medicine container should be used, and is the timing after a preset period (for example, 6 hours) has elapsed since the medicine container was opened. In addition, the control unit 41 causes the status display unit 312 to flash blue when the medicine placement unit 301 is the current placement destination of the medicine container, or when the medicine placement unit 301 is the current target for removing the medicine container. Furthermore, the control unit 41 causes the status display unit 312 to flash red when there is an error in placing the medicine container on the medicine placement unit 301 or an error in removing the medicine container.

Then, in the mixed injection support device 4, the control unit 41 executes a remaining medicine storage process and a remaining medicine utilization process to support management of the medicine containers using the medicine storage unit 300. Here, FIG. 20 is a flowchart showing an example of the remaining medicine storage process, and FIG. 23 is a flowchart showing an example of the remaining medicine utilization process. Note that either or both of the remaining medicine storage process and the remaining medicine utilization process may be executed by the control unit 21 of the mixed injection management device 2, and the mixed injection support device 4 may be used as an operation display terminal that accepts user operations or displays various screens based on information received from the mixed injection management device 2.

[Remaining medicine storage processing]
First, an example of the remaining medicine storage process will be described with reference to FIG.

<Step S31>
In step S31, the control unit 41 judges whether or not the mixing operation performed by the operator is completed based on the preparation data. Specifically, the control unit 41 judges that the mixing operation is completed when an end operation of the mixing operation is performed on the foot switch unit 45. Here, if it is judged that the mixing operation is completed (S31: Yes), the process proceeds to step S32, and if it is judged that the mixing operation is not completed (S31: No), the process proceeds to step S35.

<Step S32>
In step S32, the control unit 41 judges whether or not a residual medicine has been generated in the medicine container used in the mixed injection work. For example, the control unit 41 judges whether or not a residual medicine has been generated based on the preparation data. In addition, when the medicine container stored in the medicine storage unit 300 is used in the mixed injection work, the control unit 41 judges whether or not a residual medicine has been generated based on the remaining medicine management information described below and the preparation data. Furthermore, the control unit 41 may judge that a residual medicine has been generated when an operation input indicating that a residual medicine has been generated is performed by a user operation. Here, if it is judged that a residual medicine has been generated (S32: Yes), the process proceeds to step S33, and if it is judged that no residual medicine has been generated (S32: No), the process proceeds to step S35. In addition, when the control unit 41 judges that a residual medicine has been generated, the printer 44 prints the remaining medicine authentication label including the contents of the remaining medicine. In addition, the judgment of whether or not a residual medicine has been generated in the medicine container used in the mixed injection work and the printing of the remaining medicine authentication label may be performed before the end of the mixed injection work. In addition, in step S32, even if residual medicine remains in the medicine container used in the mixed injection operation, if the number of times the syringe has pierced the medicine container in the mixed injection operation reaches a preset number (e.g., twice) or more, the control unit 41 may determine that no residual medicine remains in the medicine container. Therefore, in the mixed injection support process, the control unit 41 executes a counting process of counting the number of times the syringe has pierced the medicine container, for example, when displaying a guide for a suction process of suctioning medicine from the medicine container.

<Step S33>
In step S33, the control unit 41 specifies, as a destination for the current medicine container, a medicine placing unit 301 on which the medicine container is not placed among the medicine placing units 301, based on the remaining medicine management information stored in the storage unit 413. When remaining medicine is generated for a plurality of the medicine containers, a destination is specified for each of the medicine containers.

Here, FIG. 21 is a diagram showing an example of the remaining medicine management information according to this embodiment. As shown in FIG. 21, the remaining medicine management information includes information such as the storage location number of the medicine storage unit 300 where the medicine is placed, medicine identification information, storage date and time, and remaining liquid amount. The remaining medicine management information is updated in step S38 or step S47 described later. The control unit 41 when executing the process for storing the remaining medicine management information in the storage unit 413 is an example of a storage processing unit in the present invention. The medicine identification information is a medicine code that can identify the type of remaining medicine. The storage date and time is information indicating the date and time when the medicine container was stored as a remaining medicine, but for example, the start date and time or end date and time of a mixing operation based on the preparation data is substituted. The remaining liquid amount is information indicating the amount of remaining medicine determined to occur in step S32. The control unit 41 may be capable of printing out a form indicating the contents of the remaining medicine management information using a printing device connected to the communication network N1.

The storage location number is a combination of a unit number, which is identification information of the medicine storage unit 300, and a shelf number, which is identification information of the medicine placement section 301 in the medicine storage unit 300. Specifically, in the medicine storage unit 300 according to this embodiment, as shown in FIG. 19, six medicine placement sections 301 are provided in the upper placement section 310, and twelve medicine placement sections 301 are provided in the lower placement section 320. In this embodiment, as shown in FIG. 22A etc., the medicine placement sections 301 in the lower placement section 320 are each set with shelf numbers "1" to "12", and the medicine placement sections 301 in the upper placement section 310 are each set with shelf numbers "21" to "26".

The control unit 41 may specify the placement destination of the drug container based on preset conditions in step S33. For example, the control unit 41 may specify the placement destination of the drug container this time so that the placement of the drug containers stored in the drug storage unit 300 is as even as possible, or so that the placement of the drug containers stored in the drug storage unit 300 is as concentrated as possible. The control unit 41 may specify the placement destination of the drug container in order from the drug placement unit 301 with the smallest shelf number, or from the drug placement unit 301 with the largest shelf number. Furthermore, the control unit 41 may specify the placement destination of the drug container from among the drug placement units 301 on which the drug container is not placed, in response to a selection operation by an operator.

<Step S34>
In step S34, the control unit 41 executes a process for notifying the medicine placing unit 301 which is to be the current placement destination of the medicine container. Specifically, the control unit 41 drives the status display unit 312 of the medicine placing unit 301 identified as the placement destination in step S33 to flash blue, indicating that the medicine container is the current placement destination.

Furthermore, the control unit 41 may repeat a sequential lighting process of sequentially lighting each of the status display units 312 in red from a reference position P20 preset in the medicine storage unit 300 toward the medicine placement unit 301 identified as the placement destination of the medicine container. This allows the operator to easily identify the medicine placement unit 301 that is the placement destination of the medicine container.

FIGS. 22A to 22D are diagrams showing an example of the sequential lighting process. First, as shown in FIG. 22A, consider the case where the shelf number of the medicine placement unit 301 specified as the placement destination of the medicine container is "1". In this case, the status display unit 312 of the medicine placement unit 301 with shelf number "1" flashes blue. Furthermore, the sequential lighting process is repeated from the reference position P20 toward the medicine placement unit 301 with shelf number "1", in which the status display units 312 of the medicine placement units 301 with shelf numbers "12" to "2" are sequentially lit red, and the position of the medicine placement unit 301 as the placement destination is guided.

As shown in FIG. 22B, consider the case where the shelf number of the medicine placement unit 301 identified as the placement destination of the medicine container is "12". In this case, the status display unit 312 of the medicine placement unit 301 with shelf number "12" flashes blue. Also, a sequential lighting process is repeated from the reference position P20 toward the medicine placement unit 301 with shelf number "12", in which the status display units 312 of the medicine placement units 301 with shelf numbers "1" to "11" are sequentially lit, and the position of the medicine placement unit 301 to be placed is guided.

As shown in FIG. 22C, consider the case where the shelf number of the medicine placement unit 301 specified as the placement destination of the medicine container is "4". In this case, the status display unit 312 of the medicine placement unit 301 with shelf number "4" flashes blue. Also, a sequential lighting process is repeated from the reference position P20 toward the medicine placement unit 301 with shelf number "4", in which the status display units 312 of the medicine placement units 301 with shelf numbers "1" to "3" are sequentially lit in red, and a sequential lighting process is repeated in which the status display units 312 of the medicine placement units 301 with shelf numbers "12" to "5" are sequentially lit. That is, the position of the medicine placement unit 301 to be placed is guided by branching left and right from the reference position P20.

As shown in FIG. 22D, consider the case where the shelf number of the medicine placement unit 301 specified as the placement destination of the medicine container is "8". In this case, the status display unit 312 of the medicine placement unit 301 with shelf number "8" flashes blue. Also, a sequential lighting process is repeated from the reference position P20 toward the medicine placement unit 301 with shelf number "8", in which the status display units 312 of the medicine placement units 301 with shelf numbers "1" to "7" are sequentially lit in red, and a sequential lighting process is repeated in which the status display units 312 of the medicine placement units 301 with shelf numbers "12" to "9" are sequentially lit. That is, the position of the medicine placement unit 301 to be placed is guided by branching left and right from the reference position P20.

It is also possible that the drug storage unit 300 is provided with a position detection unit capable of detecting the rotational positions of the upper placement unit 310 and the lower placement unit 320 of the drug storage unit 300. In this case, it is considered that the control unit 41 sets the position closest to the operator as the reference position P20 and sequentially lights up the status display units 312 of the other drug placement units 301 in red from the reference position P20 toward the drug placement unit 301 as the placement destination in step S33. It is also possible that the control unit 41, when identifying the placement destination drug placement unit 301 in step S33, identifies the drug placement unit 301 that is closest to the operator among the drug placement units 301 on which the drug container is not placed, as the placement destination of the current drug container, based on the detection result by the position detection unit. 22A to 22D, the control unit 41 may display an image indicating the reference position P20 and the position of the destination medicine loading part 301 on the operation display unit 42. In this way, for example, if the reference position P20 is marked on the medicine storage unit 300, the operator can easily grasp the position of the destination medicine loading part 301.

<Step S35>
In step S35, the control unit 41 judges whether the medicine container is placed on the medicine placing unit 301. Specifically, the control unit 41 judges whether the medicine container is placed on the medicine placing unit 301 based on the detection result by the placement detection unit 311 of each of the medicine placing units 301. Here, if it is judged that the medicine container is placed on the medicine placing unit 301 (S34: Yes), the process proceeds to step S35, and if it is not judged that the medicine container is placed on the medicine placing unit 301 (S35: No), the process returns to step S31. Note that, as another embodiment, the process may wait at step S35 until it is judged that the medicine container is placed on the medicine placing unit 301 (S35: No).

<Step S36>
In step S36, the control unit 41 judges whether the placement destination of the medicine container is correct. Specifically, when the medicine placement unit 301 of the current placement destination is specified in step S33, the control unit 41 judges that the placement destination of the medicine container is correct when the medicine container is placed on the medicine placement unit 301. Also, when the medicine placement unit 301 of the current placement destination is not specified in step S33, and the medicine container is placed on the medicine placement unit 301 in which the medicine management information has registered that the medicine container is not placed, the control unit 41 judges that the placement destination of the medicine container is incorrect. Here, when it is judged that the placement destination of the medicine container is correct (S36: Yes), the process proceeds to step S37, and when it is judged that the placement destination of the medicine container is incorrect (S36: No), the process proceeds to step S361.

<Step S361>
In step S361, the control unit 41 notifies the placement error of the medicine container, and returns the process to step S31. Specifically, the control unit 41 drives the status display unit 312 of the medicine placement unit 301 on which the medicine container is placed to flash red, which corresponds to the placement error. Furthermore, the control unit 41 causes the operation display unit 42 to display a message indicating the placement error of the medicine container. This allows the operator to easily grasp the placement error of the medicine container.

<Step S37>
In step S37, the control unit 41 executes a process for notifying the medicine placing unit 301 on which the medicine container is placed. Specifically, the control unit 41 drives the status display unit 312 of the medicine placing unit 301 on which the medicine container is placed to light up in blue, which corresponds to the placement state of the medicine container.

<Step S38>
In step S38, the control unit 41 updates the remaining medicine management information. Specifically, the control unit 41 records the storage location number, medicine identification information, storage date and time, and remaining liquid amount for the medicine container determined to have remaining medicine in step S32 in the remaining medicine management information. Note that, when the medicine container is used in a plurality of the co-infusion operations, for example, the start date and time or the end date and time of the first co-infusion operation is recorded as the storage date and time.

In the above steps S33 to S36, the control unit 41 identifies the medicine placement unit 301 on which the medicine container is to be placed and determines whether or not the medicine container should be placed on the medicine placement unit 301. On the other hand, a configuration in which the operator can arbitrarily select the placement destination of the medicine container is also conceivable. Specifically, instead of steps S33 to S36, the control unit 41 can detect the placement of the medicine container on the medicine placement unit 301 and specify the detected medicine placement unit 301 as the placement destination of the medicine container. This allows the operator to place the medicine container at an arbitrary position without searching for the medicine placement unit 301 specified by the control unit 41. In addition, when the operator operates the foot switch unit 45 to select the medicine placement unit 301 in step S33, the control unit 41 can specify the medicine placement unit 301 as the placement destination of the medicine container.

[Remaining medicine utilization]
Next, the remaining medicine utilization process will be described with reference to FIG.

<Step S41>
In step S41, the control unit 41 judges whether the remaining medicine can be used in the mixed injection work based on the preparation data selected as the processing target in the mixed injection support process based on the remaining medicine management information. Here, the control unit 41 when executing such a process is an example of a judgment processing unit in the present invention. Here, if it is judged that the remaining medicine can be used in the mixed injection work (S41: Yes), the process proceeds to step S42, and if it is judged that the remaining medicine cannot be used in the mixed injection work (S41: No), the process proceeds to step S44.

<Step S42>
In step S42, the control unit 41 judges whether or not a remaining drug that can be used in the mixing operation based on the preparation data selected as a processing target in the mixing support process has been selected. Specifically, the control unit 41 displays a list of remaining drugs that can be used in the mixing operation based on the preparation data selected as a processing target in the mixing support process on the operation display unit 42 based on the remaining drug management information, and accepts the selection operation of the remaining drug by the operator. Here, if it is determined that the remaining drug to be used has been selected (S42: Yes), the process proceeds to step S43, and if it is determined that the remaining drug to be used has not been selected (S42: No), the process proceeds to step S44.

<Step S43>
In step S43, the control unit 41 executes a process for notifying the storage location where the medicine container to be used this time is stored. Specifically, the control unit 41 drives the status display unit 312 of the medicine placement unit 301 in which the medicine container selected in step S32 is accommodated to flash blue, indicating that the medicine container is the subject of removal this time. In the following, the medicine container to be used this time among the medicine containers stored in the medicine storage unit 300 may be referred to as a remaining medicine container.

The control unit 41 may repeat a sequential lighting process of sequentially lighting each of the status display units 312 in red from a reference position P20 preset in the medicine storage unit 300 toward the medicine placement unit 301 where the medicine container to be removed is stored. This allows the operator to easily identify the medicine placement unit 301 of the medicine container to be removed. In addition, the control unit 41 may display, in the mixing support process, that the remaining medicine container will be used as the medicine container on a guidance screen that displays the contents of the mixing work (preparation procedure). The control unit 41 may display, on the operation display unit 42, an image showing the reference position P20 and the position of the medicine placement unit 301 to be removed.

<Step S44>
In step S44, the control unit 41 judges whether or not the medicine container has been removed from the medicine placement unit 301. Specifically, the control unit 41 judges whether or not the medicine container has been removed based on the detection result by the placement detection unit 311 of each of the medicine placement units 301. If it is judged that the medicine container has been removed (S44: Yes), the process proceeds to step S45, and if it is not judged that the medicine container has been removed (S44: No), the process proceeds to step S48. Note that, as another embodiment, the process may wait at step S44 until it is judged that the medicine container has been removed (S44: No).

<Step S45>
In step S45, the control unit 41 judges whether the removed medicine container is correct. Specifically, when the remaining medicine to be used is selected in step S42, the control unit 41 judges that the removed medicine container is correct if the medicine placement unit 301 corresponding to the placement detection unit 311 that detected the removal of the medicine container is registered in the remaining medicine management information as the placement destination of the remaining medicine container to be removed. The control unit 41 may also judge that the removed medicine container is correct if the one-dimensional code or two-dimensional code of the remaining medicine authentication label attached to the remaining medicine container to be removed is read by the first reading unit 43 or the second reading unit 46. Furthermore, when the medicine container to be used as the remaining medicine is not selected in step S423 and the medicine container is removed from the medicine placement unit 301 in which the medicine container is registered in the medicine management information as being placed, the control unit 41 judges that the removed medicine container is incorrect. Here, if it is determined that the removed medicine container is correct (S45: Yes), the process proceeds to step S46, and if it is determined that the removed medicine container is incorrect (S45: No), the process proceeds to step S451.

<Step S451>
In step S451, the control unit 41 notifies the removal error of the medicine container, and shifts the process to the step S48. Specifically, the control unit 41 drives the status display unit 312 of the medicine placement unit 301 from which the medicine container has been removed to flash red, corresponding to the removal error. Furthermore, the control unit 41 causes the operation display unit 42 to display a message indicating the removal error of the medicine container. This allows the operator to easily recognize the erroneous removal of the medicine container.

<Step S46>
In step S46, the control unit 41 executes a process for notifying the medicine placing unit 301 from which the remaining medicine container has been removed. Specifically, the control unit 41 turns off the status display unit 312 of the medicine placing unit 301 from which the remaining medicine container has been removed.

<Step S47>
In step S47, the control unit 41 updates the remaining medicine management information. Specifically, the control unit 41 deletes the storage location number, medicine identification information, storage date and time, and remaining liquid amount for the medicine container selected to be used as the remaining medicine in step S42 from the medicine management information.

<Step S48>
In step S48, the control unit 41 judges whether or not a medicine container whose expiration date has passed is stored in the medicine storage unit 300 based on the remaining medicine management information. Specifically, a usable period after opening of a medicine is preset for each type of medicine in the medicine master or the like, and the control unit 41 can judge whether or not the expiration date has passed based on the usable period in the medicine master and the storage date and time in the remaining medicine management information. Here, if it is judged that a medicine container whose expiration date has passed is stored (S48: Yes), the process proceeds to step S49, and if it is judged that a medicine container whose expiration date has passed is not stored (S48: No), the process returns to the step S41.

<Step S49>
In step S49, the control unit 41 notifies a request to remove the medicine container whose expiration date has arrived. Specifically, the control unit 41 drives the status display unit 312 of the medicine placement unit 301 in which the medicine container whose expiration date has arrived is stored, to flash red to indicate that the medicine container is to be removed. Furthermore, the control unit 41 displays a message on the operation display unit 42 to prompt the user to remove the medicine container whose expiration date has arrived.

Note that the management of the expiration date of the remaining medicine in steps S48 to S49 may be performed only when the following conditions (A) to (C) are met. (A) A remaining medicine authentication label including a one-dimensional code or a two-dimensional code indicating the contents of the remaining medicine is printed by the printer 44 at the start of the mixing operation, for example. (B) In the remaining medicine storage process, the removal of the medicine container from the medicine placement unit 301 is monitored. (C) When the medicine container is placed on the medicine placement unit 301, the one-dimensional code or the two-dimensional code is read by the first reading unit 43. In addition, when the removal of the medicine container is guided in step S42, the control unit 41 may determine that the removal has been completed normally and leave a record when the one-dimensional code or the two-dimensional code of the medicine container is read by the first reading unit 43.

The control unit 41 may also be capable of accepting an operation to start removing any of the drug containers in response to an arbitrary selection operation by an operator. In this case, the control unit 41 may notify a request to remove the drug container arbitrarily selected by the operator, as in step S49, and when the drug container is removed, may determine that the drug container removed in step S45 is correct. Furthermore, the control unit 41 may also notify a request to remove all of the drug containers when an operation to end work is performed by an operator or when a preset work end time arrives.

As described above, in the co-infusion support device 4, the placement location of the drug container in the drug storage unit 300 is managed, and the drug placement section 301 where the drug container is placed or the drug placement section 301 from which the drug container should be removed is notified as necessary, thereby improving the efficiency of the placement and removal of the drug container.

In the mixed injection management system 1, a plurality of the mixed injection support devices 4 may be connected, and the drug storage unit 300 may be provided in one or more of the mixed injection support devices 4. Therefore, the storage location number information may include a device number, which is identification information of the mixed injection support device 4. In addition, the remaining drug management information may be mutually referenced between the mixed injection support devices 4, the remaining drug management information may be stored and shared in a specific mixed injection support device 4, and the remaining drug management information may be synchronized between the mixed injection support devices 4. In this case, in step S33, the control unit 41 may specify not only the drug storage unit 300 of the mixed injection support device 4 in which the control unit 41 is mounted, but also the drug placement unit 301 of the drug storage unit 300 of another mixed injection support device 4 as a placement destination. In addition, when it is determined in step S41 whether the remaining medicine is available, the remaining medicine in the medicine container stored in the medicine storage unit 300 of not only the mixing support device 4 equipped with the control unit 41 but also the other mixing support device 4 may be taken into consideration. When the remaining medicine to be used is selected in step S42, not only the mixing support device 4 equipped with the control unit 41 but also the medicine container stored in the medicine storage unit 300 of the other mixing support device 4 may be selectable. In addition, when the medicine container stored in the medicine storage unit 300 of the other mixing support device 4 is selected, the control unit 41 may display the location of the medicine container on the operation display unit 42 or the like based on the medicine management information corresponding to the other mixing support device 4 in step S43.

Furthermore, it is also conceivable that the remaining drug information and the remaining drug management information can be mutually referenced between the co-injection assistance device 4 and the co-injection management device 2. In this case, the control unit 41 may be capable of taking into consideration the remaining drug stored in the automatic co-injection device 5 in the steps S41 to S43. For example, in the step S41, when the automatic co-injection device 5 has remaining drug that can be used in the co-injection work based on the preparation data, it is determined that the remaining drug is usable, and in the step S42, it is conceivable that the remaining drug stored in the automatic co-injection device 5 can be selected. In this case, in the step S43, the operation display unit 42 or the like displays that the remaining drug to be used is stored in the automatic co-injection device 5.

[Select whether or not to use remaining medicine]
In the remaining medicine use process (see FIG. 23), a configuration has been described in which a usable remaining medicine is selected when it is determined that the remaining medicine can be used in the mixed injection work based on the preparation data, and the storage location where the remaining medicine is stored is notified (S41 to S43). On the other hand, a configuration is conceivable in which the mixed injection support device 4 has a remaining medicine use/non-use selection function that allows the operator to select whether or not to use the remaining medicine when starting the mixed injection work for the preparation data that is the processing target in the mixed injection support process.

Specifically, in the co-injection support process, the control unit 41 sequentially displays on the operation display unit 42 guide screens including information regarding the work steps required for the co-injection work. For example, the work steps include the work steps required from the drug authentication step, tare step, dissolving liquid extraction step, dissolving liquid measuring step, dissolving liquid photographing step, dissolving step, drug solution extraction step, drug solution measuring step, drug solution photographing step, and co-injection step, as described above. Note that the drug authentication step is a step that is performed at least before the drug solution extraction step, and in the drug authentication step, if the drug indicated by the drug code read from the drug container by the second reading unit 46 matches the drug that is to be subjected to the drug solution extraction step, it is determined that the drug is correct.

The control unit 41 executes the remaining medicine utilization process together with the co-infusion support process, and in the remaining medicine utilization process, if the remaining medicine can be used in the co-infusion work based on the preparation data selected as the processing target of the co-infusion support process, the operator can select whether or not to use the remaining medicine. Here, FIG. 24 is a flowchart showing another example of the remaining medicine utilization process, and the control unit 41 when executing the remaining medicine utilization process is an example of a selection processing unit in the present invention.

As shown in FIG. 24, when the control unit 41 determines in step S41 that the remaining medicine can be used in the mixed injection work based on the preparation data selected as the processing target of the mixed injection support process (S41: Yes), it executes the subsequent step S411. Also, in the remaining medicine utilization process shown in FIG. 24, the step S42 is omitted.

<Step S411>
In step S411, the control unit 41 causes the operation display unit 42 to display a guide screen P11 for allowing the operator to select whether or not to use the remaining drug. Here, Fig. 25A is a diagram showing a display example of the guide screen P11.

As shown in FIG. 25A, the guidance screen P11 includes display areas A111 to A113. Specifically, the control unit 41 displays a message indicating that the remaining drug is available for use in the display area A111. The control unit 41 also displays, in the display area A112, a drug name or drug code that can identify the type of remaining drug. Furthermore, the control unit 41 displays various operation keys in the display area A113, including an operation key K111 for selecting whether to use the remaining drug and an operation key K112 for selecting whether to not use the remaining drug.

Incidentally, in the co-injection work, the amount of work (work efficiency) may differ depending on whether or not the remaining drug is used. Specifically, when only a drug container containing less remaining drug than the amount corresponding to the drug dose indicated in the preparation data is stored in the drug storage unit 300 in the safety cabinet 100, it is necessary to use the remaining drug in the remaining drug container after using the remaining drug in that drug container. Therefore, the worker must perform the work of aspirating the drug with a syringe from the drug container containing the remaining drug and the work of aspirating the drug from the other drug container, which takes longer than when aspirating the drug with a syringe from only one drug container.

The control unit 41 may therefore display information such as the amount of work (work efficiency) when the remaining drug is used and when it is not used, or the difference in the amount of work, on the guidance screen P11 of the operation display unit 42. This allows the worker to determine whether or not to use the remaining drug, taking into account the amount of work (work efficiency).

Specifically, the control unit 41 may determine the number of drug containers to be used when the remaining drug in storage is used and when it is not used based on the preparation data and the remaining drug management information. Specifically, when a drug container containing a remaining drug in an amount corresponding to the dosage of the drug indicated in the preparation data is stored in the drug storage unit 300 in the safety cabinet 100, the control unit 41 may determine that the number of drug containers to be used is the same when the remaining drug in storage is used and when a new unused drug container is used, and the amount of work (work efficiency) is the same. On the other hand, when a drug container containing a remaining drug in an amount corresponding to the dosage of the drug indicated in the preparation data is not stored in the drug storage unit 300 in the safety cabinet 100, the control unit 41 collects and uses the drug from multiple drug containers stored in the drug storage unit 300, or collects and uses the drug from both the drug container stored in the drug storage unit 300 and the new unused drug container. Therefore, in such a case, it may be determined that the number of drug containers to be used increases compared to when only new unused drug containers are used, and the amount of work (work efficiency) decreases.

Therefore, for example, the control unit 41 may display information such as the number of needle pricks by the syringe required for the mixed injection work in each case of using the remaining drug and not using the remaining drug, or whether the number of needle pricks changes depending on whether the remaining drug is used or not, based on the preparation data and the remaining drug management information. The number of needle pricks can be counted based on various preparation procedures stored in advance in the memory unit 413. Specifically, when the mixed injection work is performed using one drug container, two needle pricks are required: one when removing the drug from the drug container and one when injecting the drug into the infusion bag. On the other hand, when the mixed injection work is performed using two drug containers, two needle pricks are required each when removing the drug from the drug container and when injecting the drug into the infusion bag, so a total of four needle pricks are required. The information displayed on the guidance screen P11 may be, for example, the number of drug containers used in each of the cases where the remaining drug is used and where the remaining drug is not used, as long as the information allows the difference in the amount of work (work efficiency) between when the remaining drug is used and when the remaining drug is not used to be understood.

<Step S412>
Next, in step S412, the control unit 41 judges whether or not the operator has selected to use the remaining drug on the guidance screen P11. Specifically, in this embodiment, the control unit 41 judges that the operator has selected to use the remaining drug when the operation key K111 has been operated, and judges that the operator has selected not to use the remaining drug when the operation key K112 has been operated.

If it is determined that the remaining chemicals have been selected not to be used (S412: No), the process proceeds to step S44. Note that when the remaining chemicals have been selected not to be used, the control unit 41 may display a message or the like to reconfirm that the remaining chemicals will not be used, and allow the operator to reselect whether or not to use the remaining chemicals depending on the operator's operation in response to the message.

On the other hand, if it is determined that the remaining medicine has been selected for use (S412: Yes), the process proceeds to step S43. Then, the control unit 41 executes a process for notifying the user of the storage location of the medicine container that contains the remaining medicine to be used in step S43 (S43). The control unit 41 may also display the storage location of the medicine container in step S43 when the guidance screen P11 is displayed in step S411.

In addition, in step S43, the control unit 41 notifies the storage positions in the drug storage unit 300 of only those drug containers that contain at least the amount of drug required for the mixing operation among the drug containers that contain remaining drug that can be used in the mixing operation based on the preparation data selected as the processing target in the mixing support process. Here, in step S43, when there are multiple drug containers that contain remaining drug that can be used in the mixing operation based on the preparation data and contain the amount of drug required for the mixing operation, the control unit 41 may display the storage positions of drug containers that meet a preset selection condition from the multiple drug containers. For example, the selection condition is that the storage date and time stored in the remaining drug management information is the oldest, or that the amount of remaining liquid stored in the remaining drug management information is closest to the amount of drug required for the mixing operation.

In another embodiment, in step S43, the control unit 41 may notify the storage positions in the drug storage unit 300 of all drug containers that contain remaining drug that can be used in the mixed injection work based on the preparation data selected as the processing target in the mixed injection support process. That is, it is conceivable that the storage positions in the drug storage unit 300 of all drug containers that contain the same drug are notified, regardless of whether or not the amount of drug required for the mixed injection work is contained therein.

Furthermore, it is considered that the control unit 41 can set in advance the conditions of the drug containers whose storage positions are to be notified in step S43 in response to a user operation. For example, the control unit 41 accepts a selection of a notification mode by a user operation from a first notification mode in which the storage positions are notified only for drug containers that contain the amount of drug required for the mixing operation as described above, and a second notification mode in which the storage positions are notified for all drug containers that contain remaining drug that can be used in the mixing operation, and executes the notification in step S43 in the selected notification mode.

The control unit 41 may be capable of setting the notification mode in the initial setting of the co-injection support device 4, but may also be capable of switching the notification mode in response to a user operation while the guidance screen P11 is displayed. Furthermore, the control unit 41 may be capable of executing notification in the first notification mode when a drug container containing the amount of drug required for the co-injection work is present, and executing notification in the second notification mode when a drug container containing the amount of drug required for the co-injection work is not present.

In the remaining medicine use process (see FIG. 24), it is determined that the remaining medicine can be used in the mixed injection work based on the preparation data, and when it is determined that the remaining medicine can be used, the use of the remaining medicine is selected according to the operation of the operator. On the other hand, it is also possible that the operator knows the storage location in the medicine storage unit 300 of the medicine container containing the usable remaining medicine, or the medicine storage unit 300 is not provided in the mixed injection management system 1. Therefore, it is considered that the control unit 41 determines that the use of the remaining medicine is selected even if the one-dimensional code or two-dimensional code of the remaining medicine authentication label attached to the remaining medicine container is read by the first reading unit 43 or the second reading unit 46 in step S412. In this case, it is considered that the control unit 41 omits steps S43 to S46 in the remaining medicine use process (see FIG. 24) and shifts the process to step S47. That is, when the one-dimensional code or two-dimensional code on the remaining medicine authentication label is read in step S412, the control unit 41 can determine that the selection operation to use the remaining medicine and the authentication of the medicine container in step S45 were performed simultaneously.

In addition, when preparation data to be used in the mixing operation is selected, the control unit 41 may execute a process for confirming the state of the medicine containers, etc., used in the mixing operation, separately from the medicine authentication process, at the start of the mixing support process. The process for confirming the state of the medicine containers, etc., used in the mixing operation is executed after the preparation data is selected, at least before the remaining medicine use process (see FIG. 24) is started. Specifically, in the process for confirming the state of the medicine containers, the control unit 41 may determine that the state of the medicine containers is normal when the identification information of one or more medicine containers and infusion bags used in the mixing operation based on the preparation data is read by the first reading unit 43 or the second reading unit 46. In this case, the control unit 41 may determine that an operation to use the remaining medicine in the remaining medicine container has been performed in the mixing operation when the one-dimensional code or two-dimensional code of the remaining medicine authentication label attached to the remaining medicine container is read by the first reading unit 43 or the second reading unit 46 as the identification information of the medicine container used in the mixing operation. In this case, the control unit 41 may skip steps S41, S411, S412, and S43 to S46 in the remaining medicine utilization process (see FIG. 24) and move the process to step S47.

In the mixing operation, the drug solution extraction process may be performed to extract each of a plurality of types of drug from a drug container. That is, a plurality of drug solution extraction processes may be performed sequentially, and residual drug may be generated in a plurality of drug containers. In this case, the control unit 41 may execute the steps S41, S411, S412, and S43 at the timing when the drug solution extraction process for each drug starts in the remaining drug utilization process (see FIG. 24). In addition, when the preparation data to be the subject of the mixing operation is selected, the control unit 41 may collectively determine whether or not the residual drug can be used for each drug used in the mixing operation, and may collectively accept the operator's operation to select whether or not to use the residual drug for the drug determined to be usable at that time.

[Manual remaining liquid level registration function]
In step S38 of the remaining medicine storage process (see FIG. 20), a case has been described in which the remaining medicine management information is updated based on the preparation data in step S32, or based on the determination result of whether or not there is any remaining medicine based on the preparation data and the remaining medicine management information. That is, in step S38, the amount of remaining liquid registered in the remaining medicine management information may be automatically calculated by the control unit 41 based on the preparation data or the remaining medicine management information.

On the other hand, the co-infusion support device 4 may have a remaining liquid amount manual registration function that allows information such as the remaining liquid amount to be registered in the remaining medicine management information to be registered in response to manual operation by an operator. Specifically, when it is determined in step S32 that a remaining medicine will be generated (S32: Yes), the control unit 41 may execute a manual registration process that allows information such as the remaining liquid amount of the remaining medicine to be registered in response to a user operation before executing step S38. Note that the control unit 41 when executing the manual registration process is an example of a registration processing unit in the present invention. Specifically, in the manual registration process, the control unit 41 causes the operation display unit 42 to display a guide screen P12 that includes information such as a message indicating that a remaining medicine has been generated. Here, FIG. 25B is a diagram showing an example of the display on the guide screen P12.

As shown in FIG. 25B, the guidance screen P12 displays a display area A114 in which a message is displayed indicating that a remaining drug has occurred. In particular, the display area A114 displays information based on the remaining drug management information, such as whether or not a drug container containing the same drug as the remaining drug is stored in the drug storage unit 300 as the remaining drug, the number of bottles stored, and the total amount of remaining liquid stored. For example, the number displayed in the display area A114 is the number including the number of drug containers containing the currently occurring remaining drug, and the amount of remaining liquid displayed in the display area A114 is the amount of remaining liquid including the amount of remaining liquid of the currently occurring remaining drug.

In addition, on the guidance screen P12, the display area A113 displays an operation key K113 for selecting to store the remaining medicine generated, an operation key K114 for selecting to discard the remaining medicine generated without storing it, an operation key K115 for confirming the contents of the remaining medicine, and an operation key K116 for starting to input information such as the remaining liquid amount of the remaining medicine generated.

Then, when the operation key K113 is operated, the control unit 41 stores the information of the remaining medicine generated in the remaining medicine management information in the step S38. When the operation key K114 is operated, the remaining medicine storage process is terminated and the process is returned to step S31. When the operation key K115 is operated, the control unit 41 causes the operation display unit 42 to display the remaining medicine management information for the medicine container containing the same medicine as the remaining medicine. Furthermore, when the operation key K116 is operated, the control unit 41 causes the operation display unit 42 to display a registration screen P21 in which information such as the remaining liquid amount of the remaining medicine generated can be input. Here, FIG. 26A and FIG. 26B are diagrams showing an example of the registration screen P21. Specifically, FIG. 26A is a diagram showing an example of the registration screen P21 when the medicine initially contained in the medicine container is a liquid, and is a diagram showing an example of the registration screen P21 when the medicine initially contained in the medicine container is a powder. In another embodiment, a screen that combines the guidance screen P12 and the registration screen P21 may be displayed.

As shown in FIG. 26A, the registration screen P21 in the case where the medicine is a liquid displays the management number, medicine identification information, remaining amount, start date and time (storage start date and time), etc., included in the remaining medicine management information. In addition, the remaining medicine management information stores information such as the management number, medicine identification information, remaining amount, start date and time (storage start date and time), use date and time, mixing operation unit identification number, unit number of the medicine storage unit 300, storage location of the medicine container in the medicine storage unit 300, branch number of the management number, processing category (storing, taking out), medicine code, dissolving liquid code, dissolution amount, default amount, concentration, number of needle pricks, prescription number, Rp number, order number, etc., in association with each medicine container. The registration screen P21 may display other information such as a storage location number indicating the storage location of the medicine container. The management number is an identification number automatically assigned by the control unit 41 to identify each medicine container in the remaining medicine management information. The medicine identification information is identification information such as a medicine name or medicine code for identifying the medicine type of the remaining medicine. The remaining amount is information indicating the amount of medicine remaining in the medicine container. The start date and time is time information such as the start date and time of use when the medicine container was opened.

As shown in FIG. 26B, when the medicine is a powder, the registration screen P21 displays the item of the amount of dissolution in addition to the case where the medicine is a liquid. The amount of dissolution is information indicating the amount of liquid after dissolving the medicine, and is the amount of liquid of the solvent such as an infusion.

Furthermore, the registration screen P21 displays an input field A121 for inputting the remaining amount of the medicine, and an operation key K123 for registering the information displayed on the registration screen P21 as the remaining medicine management information. The control unit 41 can accept an operation to increase or decrease the value of the remaining amount in response to the operation of the numerical change keys K121 and K122 displayed near the input field A121. The control unit 41 can also accept the input of the remaining amount by text input or voice input after the operator selects the input field A121. After that, when the operation key K123 is operated, the control unit 41 registers the information displayed on the registration screen P21 as the remaining medicine management information. When a cancel operation is performed on the registration screen P21, the control unit 41 cancels the change of the remaining amount, closes the registration screen P21, and displays the guide screen P12. It is possible that the control unit 41 can only accept a change to the remaining liquid amount in the input field A121 on the registration screen P21, and prohibit a change to other information by, for example, graying out the other information. However, in another embodiment, the control unit 41 may also be able to accept a change to other information on the registration screen P21 other than the remaining liquid amount.

Here, the control unit 41 displays the registration screen P21 in a state where the remaining liquid amount automatically calculated based on the preparation data or the remaining medicine management information, etc., is entered into the input field A121. This makes it possible to omit the operator from inputting the numerical value if there is no change to the numerical value entered into the input field A121.

In particular, the amount of medicine contained in an unused medicine container used in the mixing operation may be greater than the preset amount set as the amount of medicine contained in the medicine container. In this case, if the amount of remaining liquid is automatically calculated based on the preparation data and the preset amount, a difference may occur between the amount of remaining liquid and the amount of remaining liquid actually remaining in the medicine container, and the medicine contained in the medicine container may not be used up in the remaining liquid utilization process. Therefore, it is considered that the control unit 41 calculates the amount of remaining liquid taking into account the actual amount of medicine contained in each medicine container.

Specifically, the control unit 41 may be capable of setting information on the actual amount of liquid contained in each medicine container in response to a user operation, separate from the preset amount of medicine registered in the medicine master stored in the storage unit 41. FIG. 27 is a diagram showing an example of a setting screen P31 of the medicine master. As shown in FIG. 27, an input field A131 corresponding to the amount of water is displayed on the setting screen P31, and the control unit 41 may set the value inputted into the input field A131 by a user operation as the actual amount of liquid. Specifically, when a registration key K131 displayed on the setting screen P31 is operated, the control unit 41 registers the information displayed on the setting screen P31 in the medicine master, or updates the medicine master based on the information displayed on the setting screen P31.

When an unused medicine container is used in the mixing operation and residual medicine is generated, the control unit 41 calculates the amount of residual liquid based on the preparation data by subtracting the amount of medicine used in the mixing operation corresponding to the preparation data from the actual amount set in the medicine master, and displays the amount of residual liquid in the input field A121. As a result, the amount of residual liquid to be stored is calculated taking into account the actual amount, so that the medicine in the medicine container stored as residual medicine can be used up as much as possible without waste. For example, even if it is determined that the amount of residual liquid calculated based on the preset amount is not sufficient to perform mixing operation using the medicine with that amount of residual liquid, it may be determined that the amount of residual liquid calculated based on the actual amount of storage can be used to perform mixing operation. Note that, when residual medicine is generated in the mixing operation using a medicine container stored in the medicine storage unit 300, the control unit 41 calculates the amount of residual liquid in the medicine container registered in the residual medicine management information minus the amount of medicine used in the mixing operation corresponding to the preparation data, and displays the amount of residual liquid in the input field A121.

Here, an example is described in which the control unit 41 can register information such as the amount of remaining liquid to be registered in the remaining medicine management information in response to manual operation by an operator when the mixing operation based on the preparation data is completed (S31: Yes). On the other hand, in the mixing operation, the drug solution extraction process may be performed for each of multiple types of drugs, in which the drug is extracted from the drug container. That is, multiple drug solution extraction processes may be performed sequentially, and residual drugs may occur in multiple drug containers. In this case, the control unit 41 may execute the manual registration process each time the drug solution extraction process for each drug is completed, and register information such as the amount of remaining liquid of the drug that is the target of the drug solution extraction process in response to manual operation by an operator. In addition, the control unit 41 may execute the manual registration process when the mixing operation is completed or when all the drug solution extraction processes are completed, and register information such as the amount of remaining liquid of each drug collectively in response to manual operation by an operator.

[Report output function]
In general, for drugs such as anticancer drugs, one drug container is administered to one patient, and one drug container is not administered to multiple patients. In contrast, as described above, in a configuration in which the remaining drug in a drug container generated in a certain mixed injection operation can be used in another mixed injection operation, the drug in the same drug container is administered to patients corresponding to multiple preparation data. Here, if any of the multiple patients to whom the drug is administered suffers a health hazard, the same health hazard may also suffer from other patients to whom the drug contained in the same drug container as the drug is administered. Therefore, it is considered that the control unit 41 has a form output function that can output the history of the mixed injection operation in which the drug container was used as a form for each drug container based on the history data of the mixed injection operation.

Specifically, the control unit 41 stores various information such as the identification information of each drug container in the mixing operation, the date and time of use, the amount taken from each drug container, the contents of the preparation data, patient information of the preparation data, and the identification information of the preparer who is the operator of the mixing operation, as history data of the mixing operation in the storage unit 413. Note that the information stored as the history data is not limited to these, as long as it is possible to identify preparation data in which the same drug container was used in the mixing operation.

Then, the control unit 41 outputs, in response to a user operation, a form P41 showing the history of the mixing work performed using each drug container based on the history data of the mixing work performed during a specified specific period, by a method such as display output or print output. Specifically, the control unit 41 outputs, based on the history data, a form P41 showing the history of the mixing work performed using the drug container only for drug containers used in mixing work based on different preparation data.

Here, FIG. 28 is a diagram showing an example of the printed form P41. As shown in FIG. 28, the form P41 shows various information for each drug container, such as the drug container's management number, drug name, date and time of use, amount taken, order number, patient name, preparer, etc. This makes it possible to use the form P41 as it is as a confirmation form for dividing and using remaining medicine (multiple use confirmation form).

[Proficiency Level Reference Allocation Function]
As described above, the distribution processing unit 211 can distribute each of the preparation data to the multiple mixing work units based on the distribution conditions. Here, the distribution processing unit 211 can have a proficiency-based distribution function that distributes each of the preparation data to the multiple mixing work units based on the mixing work proficiency of the worker working in the safety cabinet 2 as an example of the distribution condition. More specifically, the distribution processing unit 211 can distribute each of the preparation data to the multiple mixing work units based on the proficiency so that the difference in the required time for the mixing work performed by each of the mixing work units is minimized. Note that the control unit 21 can switch between enabling and disabling the proficiency-based distribution function in response to a user operation.

Specifically, the control unit 21 can register in advance worker information indicating a worker who performs the mixing work in the mixing work unit such as the safety cabinet 2 in response to a user operation, and the worker information is stored in the storage unit 22. The control unit 21 may also be able to set the worker information as the allocation condition. The worker information may be information included in the user master.

In addition, in the user master stored in the memory unit 22, the proficiency of each pharmacist who will be the operator of the mixed injection work can be registered. In particular, the control unit 21 can automatically update the proficiency of each operator, which is used as an index of the allocation condition, according to the performance of the mixed injection work of each operator. The proficiency is updated at a specific time set in advance, such as the start time or end time of business of the medical institution in which the mixed injection management system 1 is used. As a result, the proficiency is appropriately updated according to the performance of the mixed injection work for the operator, and the preparation data is appropriately allocated based on the proficiency. The control unit 41 may be able to arbitrarily change the proficiency in response to a user operation.

For example, the control unit 21 counts the number of times each of the pharmacists has performed the mixing operation, and may have a learning function that automatically updates the pharmacist's proficiency level so that the proficiency level increases as the number of times the operation is performed increases. More specifically, the control unit 21 may increase the proficiency level each time the number of times the operation is performed reaches a preset number. The control unit 21 can learn the number of times the operation is performed by acquiring information such as historical data on the mixing operation performed by each of the pharmacists from the mixing support device 4.

The control unit 21 may also update the proficiency level so that the lower the average time required for the mixing work from the start time and end time of the mixing work performed by each of the pharmacists, the higher the proficiency level. Furthermore, the control unit 21 may update the proficiency level in consideration of the relationship between the difficulty of the mixing work, such as the number of drug containers used in the mixing work or the number of needle pricks, and the time required for the mixing work. For example, the control unit 21 may update the proficiency level so that the proficiency level is higher when the difficulty is high compared to when the difficulty is low, even if the required time or the average value is the same. The control unit 21 can obtain information such as the average time required for the mixing work by each of the pharmacists by acquiring information such as history data of the mixing work by each of the pharmacists from the mixing support device 4.

Furthermore, the proficiency of each pharmacist may be updated based on accuracy information that is an index of accuracy, such as drug authentication errors, weighing errors, the number of times photography was canceled, and the number of NGs, that occurred during the mixing support process. Specifically, it is considered that the proficiency is updated so that the proficiency level decreases as the number of drug authentication errors, weighing errors, the number of times photography was canceled, and the number of NGs increases. The number of NGs is, for example, the number of times an audit conducted by an auditor other than the operator results in a NG. Note that the control unit 21 can obtain the accuracy information of each pharmacist by obtaining information such as history data of the mixing work by each pharmacist from the mixing support device 4.

The allocation processing unit 211 of the control unit 21 allocates the multiple preparation data to the multiple mixing work units based on the proficiency of the workers registered in the worker information as the workers working in each of the mixing work units. Specifically, the allocation processing unit 211 can allocate the preparation data to the multiple mixing work units based on the proficiency so that the total time required for the mixing work in the multiple mixing work units is as equal as possible.

For example, the proficiency level is a coefficient that is set in stages within a preset range, and a standard mixing operation time corresponding to each drug or regimen is preset in the pharmaceutical master. The coefficient is a value that decreases as the proficiency level increases, and may be one of five levels: "1.0", "1.2", "1.4", "1.6", and "1.8". The allocation processing unit 211 may allocate the preparation data so that the sum of the values obtained by multiplying the proficiency level by the standard mixing operation time corresponding to each drug included in the preparation data after allocation is as equal as possible. This makes it possible to allocate the preparation data to the multiple mixing operation units based on the proficiency so that the total time required for mixing operation in the multiple mixing operation units is as equal as possible.

In addition, in the mixed injection management device 2, it is considered that the control unit 21 can select an arbitrary sorting mode from a plurality of sorting modes preset as a sorting operation mode when sorting the preparation data in response to a user operation, and perform sorting. Specifically, here, an example will be described in which three sorting modes, namely, an order-based sorting mode, a medicine-saving sorting mode, and an AI sorting mode, can be selected as the sorting mode.

The order allocation mode is a mode in which the multiple preparation data are sequentially allocated to the multiple mixing work units in the input order (order order) of the preparation data. That is, in the order allocation mode, the preparation data is allocated so that the number of mixing operations in each mixing work unit is approximately the same.

The drug saving allocation mode is a mode in which the preparation data are allocated to the mixing work units so that the remaining drug generated in the mixing work can be utilized as much as possible. For example, in the drug saving allocation mode, the preparation data are allocated to the mixing work units so that the mixing work based on the preparation data using the same drug is performed in the same mixing work unit.

The AI allocation mode is a mode in which the preparation data is allocated to the mixing work units so that the total time required for the mixing work in the mixing work units is as equal as possible. In other words, the AI allocation mode is a mode in which the preparation data is allocated to the mixing work units so that the time required for the mixing work in all the mixing work units to be completed is minimized. For example, in the AI allocation mode, the preparation data is allocated to the mixing work units so that the sum of the values obtained by multiplying the standard mixing work time corresponding to each drug included in the preparation data after allocation by the proficiency is as equal as possible (the difference is minimized) in each mixing work unit. In addition, the AI allocation mode may be a mode in which preparation data in which a mixing work using residual drugs is performed and preparation data in which residual drugs are generated during the mixing work, among the plurality of preparation data, are highly difficult to perform, such as the mixing work units in which the workers with high proficiency are in charge.

The allocation processing unit 211 of the control unit 21 may have a simulation function for simulating preparation time and drug prices based on the allocation results of each of the preparation data based on the allocation operation mode. Specifically, the control unit 21 selects preparation data to be allocated from among the preparation data to be processed in one or more periods of the past, present, and future in response to a user operation. In addition, the allocation processing unit 211 can set allocation conditions such as the number of the co-infusion work units, the number of the automatic co-infusion devices 5, and whether or not remaining drugs are used in response to a user operation. Then, the allocation processing unit 211 allocates the preparation data selected as the allocation target based on the allocation conditions.

Then, the presentation processing unit 212 of the control unit 21 calculates the preparation time and drug price, etc. based on the allocation result of each of the preparation data, and displays and outputs as a simulation result on the display unit 24 or the display unit 34, or prints and outputs using a printer connected to the communication network N1. Here, FIG. 29 is a diagram showing an example of the display of the output screen P51 of the simulation result. As shown in FIG. 29, the output screen P51 displays the period of the preparation data selected as the target for allocation, the number of prescriptions indicating the number of the preparation data, and the time required for the simulation process.

The output screen P51 also displays the "number of dispensed drugs" indicating the total number of times drugs are mixed in the mixing operation based on the multiple preparation data selected as the allocation target, the "number of used drugs" indicating the number of drug containers used, the "dispensed drug price" indicating the total price of drugs corresponding to the number of dispensed drugs, the "used drug price" indicating the total price of drugs corresponding to the number of used drugs, and the "difference price" indicating the difference between the dispensed drug price and the used drug price. Note that in the mixed injection management system 1, when residual drugs generated in a preceding mixing operation are used in a subsequent mixing operation, the difference price may be suppressed, and the difference price increases as the number of times the residual drugs are used increases.

Furthermore, the output screen P51 displays information on the required time when the mixing work is performed based on the multiple preparation data selected as the allocation target. Specifically, "Preparation time (shortest day)" indicating the required time on the day when the required time is the shortest during the period of the preparation data to be allocated, "Preparation time (maximum day)" indicating the required time on the day when the required time is the longest during the period of the preparation data, and "Preparation time (average day)" indicating the average required time per day during the period of the preparation data are displayed. In the mixing management system 1, when the remaining medicine generated in the preceding mixing work is used in the subsequent mixing work, the difference price may be suppressed, and the difference price increases as the number of times the remaining medicine is used increases.

In this way, if the output screen P51 is configured to be output, the operator can easily determine the allocation operation mode that provides the desired effect from among the multiple allocation operation modes by referring to the output screen P51. Also, the output screen P51 displays a display area A151 including multiple operation keys for selecting the allocation operation mode when allocating the preparation data. Then, the control unit 21 can set the allocation operation mode when allocating the preparation data according to a user operation of the display area A151 on the output screen P51. Also, the control unit 21 may be able to change the period of the preparation data that is the subject of the simulation process on the output screen P51 according to a user operation, and execute the simulation process based on the changed period. Note that, although the case where the simulation results when allocating in each of the allocation operation modes are output simultaneously has been described here, only the simulation results when allocating in the preselected allocation operation mode may be output.

As described above, the allocation processing unit 211 may preferentially allocate preparation data for a second mixing operation that uses the same type of drug as the remaining drug generated in the preceding first mixing operation to the same mixing operation unit as the first mixing operation. On the other hand, for example, if the mixed injection management system 1 is set to not use the remaining drug, the allocation processing unit 211 will execute the allocation processing of the preparation data taking into account the proficiency. Similarly, if the mixed injection management system 1 is a system that cannot use the remaining drug generated in the preceding first mixing operation in the second mixing operation to be executed thereafter, the allocation processing unit 211 may execute the allocation processing of the preparation data taking into account the proficiency.

In addition, in the mixed injection management system 1 according to this embodiment, the allocation of preparation data that is the subject of mixed injection work performed using a syringe has been described. On the other hand, it is also possible to allocate prescription data or dispensing data that is the subject of dispensing work such as picking work or weighing work that is performed without using a syringe according to the proficiency of the worker.

In the mixed injection management system 1, the preparation data to be the subject of the mixed injection work in the mixed injection support device 4 or the automatic mixed injection device 5 may be arbitrarily selectable in the mixed injection support device 4 or the automatic mixed injection device 5. In this case, for example, the operator can select the preparation data to be the subject of the mixed injection work in the mixed injection support device 4 or the automatic mixed injection device 5 while referring to the printout of the allocation result presented by the presentation processing unit 212, and perform the mixed injection work. However, the allocation processing unit 211 may limit the selection of the preparation data by the mixed injection support device 4 or the automatic mixed injection device 5 corresponding to each of the mixed injection work units to the preparation data allocated to the mixed injection work unit according to the allocation result by the allocation processing unit 211. That is, when the mixed injection work unit selects the preparation data, if the preparation data is not allocated to the mixed injection work unit, the allocation processing unit 211 may display a message indicating that, or prohibit the selection of the preparation data.

On the other hand, the allocation processing unit 211 may transmit each of the preparation data to the mixing support device 4 or the automatic mixing support device 5 corresponding to the mixing work unit to which the preparation data is allocated, as preparation data to be subjected to the mixing work in the mixing work unit, according to the allocation result by the allocation processing unit 211. This allows the worker to use the mixing support device 4 to sequentially perform only the mixing work for the preparation data allocated to the mixing support device 4. Furthermore, the automatic mixing support device 5 can automatically perform the mixing work in sequence based on the allocation result.

Incidentally, in the automatic co-injection device 5, similarly to the co-injection work performed in the safety cabinet 100, it is possible to use the remaining medicine generated in the preceding first automatic co-injection process in a second automatic co-injection process using the same type of medicine as the remaining medicine. In this case, in the automatic co-injection device 5, the medicine container containing the remaining medicine is stored in the above-mentioned shelf or the like in the automatic co-injection device 5 until it is next used. Incidentally, the co-injection processing chamber 203 of the automatic co-injection device 5 is provided with a lighting device such as a fluorescent lamp that illuminates the co-injection processing chamber 203, and the control unit 51 can control the turning on and off of the lighting device. For example, it is possible that the control unit 51 turns on the lighting device when the automatic co-injection process is performed by the automatic co-injection device 5 or when the power supply of the automatic co-injection device 5 is ON. On the other hand, when a medicine container containing the remaining medicine is stored in the co-injection processing chamber 203, it is possible that the remaining medicine is a light-shielding target drug such as an anticancer drug (e.g., dacarbacine) that requires light shielding. However, if the lighting device in the mixed injection processing chamber 203 is in a lit state, the light-shielding target drug cannot be stored in the mixed injection processing chamber 203 as the remaining drug and used in the subsequent automatic mixed injection processing. Therefore, when the remaining drug contained in the drug container stored in the mixed injection processing chamber 203 is a light-shielding target drug, the control unit 51 may turn off the lighting device until the remaining drug is used or until the drug container is discarded. This makes it possible to use the remaining drug in the subsequent automatic mixed injection processing even if the remaining drug is a light-shielding target drug. In particular, when the light-shielding target drug is stored in a syringe or the like that does not have light-shielding properties and stored on the above-mentioned shelf, the turning off process of the lighting device is preferable. In addition, the lighting device may be controlled to be turned off while the light-shielding target drug is stored in the mixed injection processing chamber 203, not limited to the remaining drug. In addition, if the lighting device of the mixed injection processing chamber 203 is turned off while the automatic mixed injection processing is being performed, it is considered that this will interfere with the photography by the camera installed in the mixed injection processing chamber 203. Therefore, it is also possible that the camera is an infrared compatible camera, or that the control unit 51 turns on the lighting device only when photography is being performed by the camera.

In addition, after the injection process of injecting the medicine in the syringe into the infusion bag in the automatic co-infusion device 5 is performed, the medicine or infusion may be attached to the mouth of the infusion bag. Therefore, after the injection process is performed, the control unit 51 may control the first robot arm 551 or the second robot arm 552 to perform a wiping process of wiping the mouth of the infusion bag with a wiping member such as a cotton ball soaked in a disinfectant such as alcohol. In this case, when the automatic co-infusion process is performed in the automatic co-infusion device 5, a tray on which the wiping member is placed is loaded by the user along with the medicine container, the infusion bag, the syringe, etc. used in the automatic co-infusion process. However, if the wiping member is placed on the tray in an exposed state, if the automatic co-infusion process using the tray is not performed immediately after the tray is loaded into the automatic co-infusion device 5, the disinfectant that has permeated the wiping member may dry out and decrease before the wiping member is used. Therefore, when the wiping member is placed on the tray, it is considered that the wiping member is placed on the tray in a state in which it is contained in a sealed sealed container. Then, when the automatic co-infusion process is performed, the control unit 51 controls the first robot arm 551 or the second robot arm 552, etc. to open the sealed container, remove the wiping member contained in the sealed container, and perform the wiping process. Note that the method of opening the sealed container by the first robot arm 551 or the second robot arm 552, etc. is not particularly limited, but for example, it is considered that the sealed container is held by either one of the first robot arm 551 or the second robot arm 552, and a part of the sealed container (a lid member such as a sealing film) is peeled off by the other, so that the wiping process is exposed and can be taken out. In addition, for example, the sealed container may be held by either the first robot arm 551 or the second robot arm 552, and the other may break through a part of the sealed container (a lid member such as a sealing film) to expose the wiping member and make it removable. Note that the object to be wiped by the wiping member is not limited to the infusion bag, and the same applies when a wiping process is performed in which the mouth of the medicine container is wiped by the wiping member.

[Notes on the invention]
The following will describe the technical ideas of the invention extracted from the above-described embodiment. It is also possible to select and combine the respective configurations and processing functions described below in any desired manner.

<Appendix 1>
A distribution processing unit that distributes a plurality of preparation data related to a mixed injection operation of collecting medicine and injecting it into an infusion container to a plurality of mixed injection operation units where the mixed injection operation is performed based on remaining medicine generated in a preceding mixed injection operation;
a presentation processing unit that presents information regarding a result of the allocation by the allocation processing unit;
A mixed injection management system equipped with

<Appendix 2>
The allocation processing unit preferentially allocates preparation data relating to a second mixed injection operation using the same type of drug as the remaining drug generated in the preceding first mixed injection operation to the same mixed injection operation unit as the first mixed injection operation.
2. The mixed injection management system according to claim 1.

<Appendix 3>
The distribution processing unit distributes each of the preparation data to the plurality of mixed injection work units based on a predetermined distribution condition in addition to the remaining medicine.
The mixed injection management system according to claim 1 or 2.

<Appendix 4>
The allocation conditions include at least one of conditions regarding the time of execution of the mixing work corresponding to each of the preparation data, the time of administration of the medicine collected in the mixing work, the work time required for the mixing work, the number of times the medicine is collected from the medicine container in the mixing work, whether or not the remaining medicine is used in the mixing work, the type of medicine collected in the mixing work, the drug price of the medicine collected in the mixing work, the price of the closed drug transport system used in the mixing work, and the usable period of the remaining medicine generated in the mixing work.
4. The mixed injection management system according to claim 3.

<Appendix 5>
The allocation processing unit can allocate each of the preparation data to the multiple mixed injection work units so as to minimize the cost required for the mixed injection work corresponding to the multiple preparation data.
The mixed injection management system according to any one of appendix 1 to 4.

<Appendix 6>
The allocation conditions include the proficiency of the workers who perform the mixed injection work in each of the mixed injection work units.
5. The mixed injection management system according to claim 3 or 4.

<Appendix 7>
The allocation processing unit can allocate each of the preparation data to the multiple mixed injection work units so as to minimize the difference in the required time for the mixed injection work performed in each of the mixed injection work units based on the proficiency of the worker performing the mixed injection work in each of the mixed injection work units.
7. The mixed injection management system according to claim 6.

<Appendix 8>
The allocation processing unit is capable of allocating each of the preparation data to the plurality of mixed injection work units so as to minimize the number of times that the medicine is collected from the medicine container in the mixed injection work corresponding to the plurality of preparation data.
The mixed injection management system according to any one of appendix 1 to 7.

<Appendix 9>
The distribution processing unit executes a grouping process of grouping one or more preparation data corresponding to a mixing operation in which the remaining drug is generated and one or more preparation data corresponding to a mixing operation in which the remaining drug is used as one preparation data group, a first distribution process of distributing the preparation data belonging to the preparation data group to the multiple mixing operation units in units of the preparation data group, and a second distribution process of distributing the preparation data not belonging to the preparation data group after the first distribution process to the multiple mixing operation units.
The mixed injection management system according to any one of appendix 1 to 8.

<Appendix 10>
When the remaining drug that can be used in the mixed injection work exists, a display screen is displayed on which the user can select whether or not to use the remaining drug, and a selection processing unit is provided that can select whether or not to use the remaining drug in response to a user operation on the display screen.
The mixed injection management system according to any one of appendix 1 to 9.

<Appendix 11>
The selection processing unit is capable of displaying information on the amount of work in a case where the remaining drug is used and a case where the remaining drug is not used, or information suggesting a difference in the amount of work, on the display screen.
The mixed injection management system according to claim 10.

<Appendix 12>
A memory processing unit that stores remaining drug management information including the amount of remaining drug remaining in the mixed injection work in a memory unit;
A determination processing unit that determines whether or not there is a remaining drug that can be used in the mixed injection work based on the remaining drug management information stored in the memory unit;
a registration processing unit capable of registering the amount of the remaining medicine in the remaining medicine management information in response to a user operation;
The mixed injection management system according to any one of appendices 1 to 11, comprising:

<Appendix 13>
The plurality of mixing work units includes one or more manual work units in which the mixing work is performed by a person, and one or more automatic work units in which the mixing work is performed by a robot,
The allocation processing unit preferentially allocates preparation data that matches an automatic operation condition indicating a condition for allocation to the automatic operation unit to the automatic operation unit.
The mixed injection management system according to any one of appendix 1 to 12.

<Appendix 14>
The plurality of mixing work units includes one or more manual work units in which the mixing work is performed by a person, and one or more automatic work units in which the mixing work is performed by a robot,
The allocation processing unit preferentially allocates preparation data that matches a manual work condition indicating a condition for allocation to the manual work unit to the manual work unit.
The mixed injection management system according to any one of appendix 1 to 13.

<Appendix 15>
The presentation processing unit presents the preparation data sorted by the sorting processing unit in such a manner that the preparation data corresponding to the mixed injection work in which residual medicine is generated and the preparation data corresponding to the mixed injection work in which residual medicine is not generated can be distinguished from each other.
The mixed injection management system according to any one of appendix 1 to 14.

<Appendix 16>
The presentation processing unit presents, with respect to the preparation data allocated by the allocation processing unit, preparation data corresponding to a mixing operation using a remaining drug generated in a preceding mixing operation and preparation data corresponding to a mixing operation not using a remaining drug generated in a preceding mixing operation in a manner that allows them to be distinguished from each other.
The mixed injection management system according to any one of appendix 1 to 15.

<Appendix 17>
The presentation processing unit is capable of presenting a difference between a total amount of medicine required when the remaining medicine is used according to the allocation result by the allocation processing unit and a total amount of medicine required when the remaining medicine is not used.
The mixed injection management system according to any one of appendix 1 to 16.

<Appendix 18>
The presentation processing unit is capable of presenting an amount of money corresponding to the remaining medicine that will ultimately be wasted when a mixed injection operation corresponding to the plurality of preparation data is performed according to the allocation result by the allocation processing unit.
The mixed injection management system according to any one of appendix 1 to 17.

<Appendix 19>
a remaining amount calculation processing unit that calculates a remaining amount of a remaining drug generated in a mixed injection operation corresponding to the preparation data based on a dose of the drug indicated in the preparation data and the predetermined amount of the drug container in which the drug is contained;
Further provided is a management processing unit that manages the type and amount of remaining drugs remaining in one or more drug containers in each of the mixed injection work units based on the calculation result of the remaining amount calculation processing unit,
The presentation processing unit is capable of presenting the current remaining amount of each medicine based on the information on the type and remaining amount of the remaining medicine managed by the management processing unit.
The mixed injection management system according to any one of appendix 1 to 18.

<Appendix 20>
One or more processors,
A distribution step of distributing a plurality of preparation data related to a mixed injection operation of collecting a drug and injecting it into an infusion container to a plurality of mixed injection operation units where the mixed injection operation is performed based on a remaining drug generated in a preceding mixed injection operation;
a presentation step of presenting information regarding a result of the allocation step;
A mixed injection management program to implement the above.

<Appendix 21>
A distribution step of distributing a plurality of preparation data related to a mixed injection operation of collecting a drug and injecting it into an infusion container to a plurality of mixed injection operation units where the mixed injection operation is performed based on a remaining drug generated in a preceding mixed injection operation;
a presentation step of presenting information regarding a result of the allocation step;
A method for managing mixed injections, including:

Reference Signs List 1 Mixed injection management system 2 Mixed injection management device 21 Control unit 211 Allocation processing unit 212 Presentation processing unit 213 Remaining amount calculation processing unit 214 Remaining amount management processing unit 3 Client terminal 4 Mixed injection support device 5 Automatic mixed injection device 100 Safety cabinet 101 Working room 203 Mixed injection processing room

Claims (10)

A co-injection system that displays a display screen on a display unit that displays remaining drug information including at least drug identification information and remaining amount of the drug remaining in the drug container after dispensing, and includes a control unit that stores the remaining drug information displayed on the display screen in a storage unit in response to a user operation. The remaining medicine information is stored in the storage unit in association with identification information for identifying the medicine container corresponding to the remaining medicine information.
The co-infusion system of claim 1. The control unit is capable of changing at least a part of the remaining medicine information displayed on the display unit in response to a user operation.
The co-injection system according to claim 1 or 2. The control unit is capable of changing only the remaining amount of the remaining medicine information displayed on the display unit in response to a user operation, and does not change other information in response to a user operation.
The co-infusion system according to claim 3. When the control unit determines that a medicine remains in the medicine container after dispensing based on prescription data, the control unit displays the display screen based on the prescription data.
The mixed injection system according to any one of claims 1 to 4. When the control unit determines based on the prescription data that a medicine remains in the medicine container after dispensing, the control unit displays on the display unit an operation unit for receiving a user operation as to whether or not to store the remaining medicine information for the medicine, and then, when a user operation is performed to store the remaining medicine information, causes the control unit to display the display screen on the display unit, and when a user operation is performed not to store the remaining medicine information, does not display the display screen on the display unit and does not store the remaining medicine information in the storage unit.
The co-infusion system according to claim 5. The control unit changes an amount of the remaining medicine information to be displayed on the display unit depending on the type of medicine contained in the medicine container.
The mixed injection system according to any one of claims 1 to 6. When the type of the medicine is a powder medicine, the control unit causes the display unit to display the remaining medicine information including the amount of liquid after dissolving the medicine.
The co-infusion system according to claim 7. the control unit causes the display unit to display a value obtained by subtracting an amount of the drug used in dispensing from an amount of the drug contained in the drug container as the remaining amount.
The mixed injection system according to any one of claims 1 to 8. To the processor,
displaying, on a display unit, a display screen on which remaining medicine information including at least medicine identification information and a remaining amount of the medicine remaining in the medicine container after dispensing is displayed;
storing the remaining medicine information displayed on the display screen in a storage unit in response to a user operation;
A mixed injection management program to implement the above.