JP7471660B2 - グリコーゲンシンターゼキナーゼ３型β阻害剤による特発性肺線維症の治療 - Google Patents
グリコーゲンシンターゼキナーゼ３型β阻害剤による特発性肺線維症の治療 Download PDFInfo
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
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| CN117981712B (zh) * | 2023-07-24 | 2025-02-28 | 南京鼓楼医院 | 一种腺病毒诱导肺纤维化急性加重动物模型的建立方法 |
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| WO2008077138A1 (en) | 2006-12-19 | 2008-06-26 | The Board Of Trustees Of The University Of Illinois | 3-benzofuranyl-4-indolyl maleimides as potent gsk3 inhibitors for neurogenerative disorders |
| JP2009508947A (ja) | 2005-09-20 | 2009-03-05 | ニューヨーク・ユニバーシティ | インターフェロンを用いる肺疾患の処置方法 |
| JP2014503598A (ja) | 2011-01-31 | 2014-02-13 | ジェノア ファーマシューティカルズ，インク． | エアロゾルのピルフェニドンおよびピリドンアナログの化合物、および、その使用 |
| JP2015535233A (ja) | 2012-10-31 | 2015-12-10 | ガレクト・バイオテック・エイビイ | ガレクチン−３のガラクトシド阻害剤及び肺線維症のためのその使用 |
| JP2016527275A (ja) | 2013-07-31 | 2016-09-08 | ウインドワード ファーマ，インク． | エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用 |
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| KR101862291B1 (ko) * | 2011-04-12 | 2018-05-29 | 모레 매트릭스 인코포레이티드 | 이상 섬유모세포 증식 및 세포외 기질 침착을 특징으로 하는 질병, 질환, 또는 과정을 예방하거나 치료하기 위한 조성물 및 방법 |
| US20160375006A1 (en) | 2012-10-12 | 2016-12-29 | The Broad Institute, Inc. | Uses of paralog-selective inhibitors of gsk3 kinases |
| WO2014165851A1 (en) | 2013-04-05 | 2014-10-09 | The Children's Hospital Of Philadelphia | Transient up-regulation of myc in b-cell lymphomas |
| US20170165230A1 (en) | 2014-04-09 | 2017-06-15 | Christopher Rudd | Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity |
| JP6534098B2 (ja) | 2014-09-12 | 2019-06-26 | 国立大学法人 鹿児島大学 | 成人ｔ細胞白血病治療薬 |
| EP3665176B1 (en) * | 2017-08-11 | 2024-01-24 | Actuate Therapeutics Inc. | Solid forms of 3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5h[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione |
| PL3697794T3 (pl) * | 2017-10-16 | 2026-04-07 | Actuate Therapeutics Inc. | Stałe postacie 3-(5-fluorobenzofuran-3-ylo)-4-(5-metylo-5h-[1,3]dioksolo[4,5-f]indol-7-ilo)pirolo-2,5-dionu |
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| WO2008077138A1 (en) | 2006-12-19 | 2008-06-26 | The Board Of Trustees Of The University Of Illinois | 3-benzofuranyl-4-indolyl maleimides as potent gsk3 inhibitors for neurogenerative disorders |
| JP2014503598A (ja) | 2011-01-31 | 2014-02-13 | ジェノア ファーマシューティカルズ，インク． | エアロゾルのピルフェニドンおよびピリドンアナログの化合物、および、その使用 |
| JP2015535233A (ja) | 2012-10-31 | 2015-12-10 | ガレクト・バイオテック・エイビイ | ガレクチン−３のガラクトシド阻害剤及び肺線維症のためのその使用 |
| JP2016527275A (ja) | 2013-07-31 | 2016-09-08 | ウインドワード ファーマ，インク． | エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用 |
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| EP3793545A1 (en) | 2021-03-24 |
| AU2019271285A1 (en) | 2020-12-03 |
| IL278761B1 (en) | 2024-11-01 |
| BR112020023422A2 (pt) | 2021-02-17 |
| IL278761B2 (en) | 2025-03-01 |
| JP2021523951A (ja) | 2021-09-09 |
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