JP7454855B2 - 抗preS1抗体およびその用途 - Google Patents

抗preS1抗体およびその用途 Download PDF

Info

Publication number
JP7454855B2
JP7454855B2 JP2020561546A JP2020561546A JP7454855B2 JP 7454855 B2 JP7454855 B2 JP 7454855B2 JP 2020561546 A JP2020561546 A JP 2020561546A JP 2020561546 A JP2020561546 A JP 2020561546A JP 7454855 B2 JP7454855 B2 JP 7454855B2
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
seq
antibody
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2020561546A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2020130138A5 (https=
JPWO2020130138A1 (ja
Inventor
一彰 茶山
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hiroshima University NUC
Original Assignee
Hiroshima University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hiroshima University NUC filed Critical Hiroshima University NUC
Publication of JPWO2020130138A1 publication Critical patent/JPWO2020130138A1/ja
Publication of JPWO2020130138A5 publication Critical patent/JPWO2020130138A5/ja
Application granted granted Critical
Publication of JP7454855B2 publication Critical patent/JP7454855B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2020561546A 2018-12-21 2019-12-20 抗preS1抗体およびその用途 Active JP7454855B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018239719 2018-12-21
JP2018239719 2018-12-21
PCT/JP2019/050139 WO2020130138A1 (ja) 2018-12-21 2019-12-20 抗preS1抗体およびその用途

Publications (3)

Publication Number Publication Date
JPWO2020130138A1 JPWO2020130138A1 (ja) 2021-11-25
JPWO2020130138A5 JPWO2020130138A5 (https=) 2022-11-30
JP7454855B2 true JP7454855B2 (ja) 2024-03-25

Family

ID=71101303

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020561546A Active JP7454855B2 (ja) 2018-12-21 2019-12-20 抗preS1抗体およびその用途

Country Status (2)

Country Link
JP (1) JP7454855B2 (https=)
WO (1) WO2020130138A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112920277B (zh) * 2021-01-27 2022-08-09 中国农业大学 分析溴氰虫酰胺和氯虫苯甲酰胺残留的vhh-elisa试剂盒及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018519804A (ja) 2015-05-22 2018-07-26 フアフイ ヘルス リミテッドHuahui Health Ltd. 抗Pre−S1 HBV抗体
JP2018533937A (ja) 2015-10-09 2018-11-22 シャアメン ユニバーシティ B型肝炎表面抗原に対する抗体及びその使用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018519804A (ja) 2015-05-22 2018-07-26 フアフイ ヘルス リミテッドHuahui Health Ltd. 抗Pre−S1 HBV抗体
JP2018533937A (ja) 2015-10-09 2018-11-22 シャアメン ユニバーシティ B型肝炎表面抗原に対する抗体及びその使用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MAENG, Cheol-Young et al.,Fine Mapping of Virus-Neutralizing Epitopes on Hepatitis B virus PreS1,Virology,2000年,Vol. 270,p. 9-16,abstract, p. 10 , FIG.1

Also Published As

Publication number Publication date
WO2020130138A1 (ja) 2020-06-25
JPWO2020130138A1 (ja) 2021-11-25

Similar Documents

Publication Publication Date Title
JP7837375B2 (ja) ピログルタメートアミロイド-βに対する抗体及びその使用
US20210403536A1 (en) Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
TWI673287B (zh) 抗b7-h3抗體、其抗原結合片段及其醫藥用途
KR101889466B1 (ko) FcRn 특이적 인간 항체 및 이를 포함하는 자가면역질환 치료용 조성물
US10047156B2 (en) Anti-CXCL1, CXCL7 and CXCL8 antibodies and their applications
JP2022115986A (ja) ピログルタメートアミロイド-βに対する抗体及びその使用
KR102661060B1 (ko) 항인간 IgG4 모노클로날 항체, 및 그 항체를 이용한 인간 IgG4 측정 시약
MX2011001363A (es) Anticuerpos selectivos de anti-hepcidina-25 y usos de los mismos.
CN113227148B (zh) 抗gpc3抗体、其抗原结合片段及其医药用途
WO2022176970A1 (ja) 新規抗pad4抗体
JP2025020209A (ja) インターロイキン-19を標的とする化合物および方法
CN112243443A (zh) 抗trop-2抗体、其抗原结合片段及其医药用途
JP7454855B2 (ja) 抗preS1抗体およびその用途
KR20220110522A (ko) 항gdf15 항체
RU2846901C1 (ru) Антитело против trop-2, его антигенсвязывающий фрагмент или его мутант и его медицинское применение
JP2024089366A (ja) 抗HBs抗体およびその用途
RU2025105360A (ru) Связывание антител с рецептором тиреотропного гормона и их применение
RU2822520C2 (ru) Методы предсказания, обнаружения и уменьшения неспецифической интерференции белков в способах анализа с использованием одиночных вариабельных доменов иммуноглобулинов
RU2798971C2 (ru) Методы предсказания, обнаружения и уменьшения неспецифической интерференции белков в способах анализа с использованием одиночных вариабельных доменов иммуноглобулинов
CN119677537A (zh) 用于治疗狼疮性肾炎的组合物和方法
US20230374149A1 (en) Anti-trop-2 antibody, antigen-binding fragment thereof or mutant thereof, and medical use thereof
HK40049006B (en) Anti-gpc3 antibody, antigen-binding fragment thereof, and medical use thereof
HK40049006A (en) Anti-gpc3 antibody, antigen-binding fragment thereof, and medical use thereof
HK40036076A (en) Anti-trop-2 antibody, antigen binding fragment thereof and medical use thereof
JP2011160696A (ja) 修飾ヒトigf−1/eペプチドに対する抗体

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20221121

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20221121

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20231031

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20231212

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20240220

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20240305

R150 Certificate of patent or registration of utility model

Ref document number: 7454855

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350