JP7388750B2 - 動植物摂取用水溶性ナノコロイドシリカの製造方法、及び動植物摂取用水溶性ナノコロイドシリカ - Google Patents
動植物摂取用水溶性ナノコロイドシリカの製造方法、及び動植物摂取用水溶性ナノコロイドシリカ Download PDFInfo
- Publication number
- JP7388750B2 JP7388750B2 JP2021502100A JP2021502100A JP7388750B2 JP 7388750 B2 JP7388750 B2 JP 7388750B2 JP 2021502100 A JP2021502100 A JP 2021502100A JP 2021502100 A JP2021502100 A JP 2021502100A JP 7388750 B2 JP7388750 B2 JP 7388750B2
- Authority
- JP
- Japan
- Prior art keywords
- water
- soluble
- silica
- nanocolloidal
- nanocolloidal silica
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 title claims description 373
- 239000000377 silicon dioxide Substances 0.000 title claims description 177
- 238000004519 manufacturing process Methods 0.000 title claims description 30
- 241001465754 Metazoa Species 0.000 title claims description 11
- 230000037406 food intake Effects 0.000 title claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 39
- 229910052710 silicon Inorganic materials 0.000 claims description 33
- 239000010703 silicon Substances 0.000 claims description 32
- 235000012239 silicon dioxide Nutrition 0.000 claims description 32
- -1 silicate ion Chemical class 0.000 claims description 30
- 239000002245 particle Substances 0.000 claims description 23
- 239000011734 sodium Substances 0.000 claims description 18
- 239000000463 material Substances 0.000 claims description 17
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 14
- 229910001415 sodium ion Inorganic materials 0.000 claims description 13
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 11
- 229910052799 carbon Inorganic materials 0.000 claims description 11
- 239000000843 powder Substances 0.000 claims description 9
- 239000000376 reactant Substances 0.000 claims description 9
- 239000003513 alkali Substances 0.000 claims description 8
- 239000001257 hydrogen Substances 0.000 claims description 8
- 229910052739 hydrogen Inorganic materials 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 8
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 7
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 7
- 238000000921 elemental analysis Methods 0.000 claims description 7
- 239000001569 carbon dioxide Substances 0.000 claims description 6
- 239000007789 gas Substances 0.000 claims description 6
- 239000007864 aqueous solution Substances 0.000 claims description 5
- 238000002149 energy-dispersive X-ray emission spectroscopy Methods 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 229910052708 sodium Inorganic materials 0.000 claims description 3
- 238000001514 detection method Methods 0.000 claims description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 31
- 230000000694 effects Effects 0.000 description 23
- 238000005259 measurement Methods 0.000 description 21
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 18
- 239000013078 crystal Substances 0.000 description 15
- 230000036541 health Effects 0.000 description 15
- 238000006243 chemical reaction Methods 0.000 description 14
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 14
- 210000004027 cell Anatomy 0.000 description 12
- 238000000034 method Methods 0.000 description 12
- 239000010453 quartz Substances 0.000 description 12
- 229910052760 oxygen Inorganic materials 0.000 description 11
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 10
- 239000001301 oxygen Substances 0.000 description 10
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 description 10
- 206010028980 Neoplasm Diseases 0.000 description 9
- 201000011510 cancer Diseases 0.000 description 8
- 239000008119 colloidal silica Substances 0.000 description 8
- 235000013305 food Nutrition 0.000 description 8
- 235000012000 cholesterol Nutrition 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- 241000700159 Rattus Species 0.000 description 6
- 235000019353 potassium silicate Nutrition 0.000 description 6
- 239000002994 raw material Substances 0.000 description 6
- 235000011121 sodium hydroxide Nutrition 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 240000007594 Oryza sativa Species 0.000 description 5
- 235000007164 Oryza sativa Nutrition 0.000 description 5
- 229910004298 SiO 2 Inorganic materials 0.000 description 5
- 230000002411 adverse Effects 0.000 description 5
- 235000013361 beverage Nutrition 0.000 description 5
- 235000021186 dishes Nutrition 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 235000009566 rice Nutrition 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 239000004115 Sodium Silicate Substances 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 210000004204 blood vessel Anatomy 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 238000009826 distribution Methods 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000009467 reduction Effects 0.000 description 4
- 229910052911 sodium silicate Inorganic materials 0.000 description 4
- 108010023302 HDL Cholesterol Proteins 0.000 description 3
- 108010028554 LDL Cholesterol Proteins 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- 235000003953 Solanum lycopersicum var cerasiforme Nutrition 0.000 description 3
- 240000003040 Solanum lycopersicum var. cerasiforme Species 0.000 description 3
- 244000269722 Thea sinensis Species 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000003610 charcoal Substances 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 239000010419 fine particle Substances 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 229910021421 monocrystalline silicon Inorganic materials 0.000 description 3
- 230000000149 penetrating effect Effects 0.000 description 3
- IEQIEDJGQAUEQZ-UHFFFAOYSA-N phthalocyanine Chemical compound N1C(N=C2C3=CC=CC=C3C(N=C3C4=CC=CC=C4C(=N4)N3)=N2)=C(C=CC=C2)C2=C1N=C1C2=CC=CC=C2C4=N1 IEQIEDJGQAUEQZ-UHFFFAOYSA-N 0.000 description 3
- 239000002244 precipitate Substances 0.000 description 3
- 230000001603 reducing effect Effects 0.000 description 3
- 235000013311 vegetables Nutrition 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 102000018832 Cytochromes Human genes 0.000 description 2
- 108010052832 Cytochromes Proteins 0.000 description 2
- 102000053602 DNA Human genes 0.000 description 2
- 108020004414 DNA Proteins 0.000 description 2
- 208000032928 Dyslipidaemia Diseases 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 239000005909 Kieselgur Substances 0.000 description 2
- 208000017170 Lipid metabolism disease Diseases 0.000 description 2
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 2
- RYMZZMVNJRMUDD-UHFFFAOYSA-N SJ000286063 Natural products C12C(OC(=O)C(C)(C)CC)CC(C)C=C2C=CC(C)C1CCC1CC(O)CC(=O)O1 RYMZZMVNJRMUDD-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 206010000496 acne Diseases 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 239000006229 carbon black Substances 0.000 description 2
- 230000020411 cell activation Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000010411 cooking Methods 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000002542 deteriorative effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 238000001962 electrophoresis Methods 0.000 description 2
- 229940088598 enzyme Drugs 0.000 description 2
- 235000009569 green tea Nutrition 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 235000010755 mineral Nutrition 0.000 description 2
- 210000003470 mitochondria Anatomy 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000002101 nanobubble Substances 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000007670 refining Methods 0.000 description 2
- 235000014102 seafood Nutrition 0.000 description 2
- RYMZZMVNJRMUDD-HGQWONQESA-N simvastatin Chemical compound C([C@H]1[C@@H](C)C=CC2=C[C@H](C)C[C@@H]([C@H]12)OC(=O)C(C)(C)CC)C[C@@H]1C[C@@H](O)CC(=O)O1 RYMZZMVNJRMUDD-HGQWONQESA-N 0.000 description 2
- 229960002855 simvastatin Drugs 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 239000008399 tap water Substances 0.000 description 2
- 235000020679 tap water Nutrition 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 239000000052 vinegar Substances 0.000 description 2
- 235000021419 vinegar Nutrition 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 238000000733 zeta-potential measurement Methods 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 description 1
- 206010003645 Atopy Diseases 0.000 description 1
- 235000007319 Avena orientalis Nutrition 0.000 description 1
- 244000075850 Avena orientalis Species 0.000 description 1
- 208000037157 Azotemia Diseases 0.000 description 1
- 208000035985 Body Odor Diseases 0.000 description 1
- 235000011293 Brassica napus Nutrition 0.000 description 1
- 240000008100 Brassica rapa Species 0.000 description 1
- 235000000540 Brassica rapa subsp rapa Nutrition 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 102000011727 Caspases Human genes 0.000 description 1
- 108010076667 Caspases Proteins 0.000 description 1
- 241000196222 Codium fragile Species 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 206010010144 Completed suicide Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 206010019133 Hangover Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000004044 Hypesthesia Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000589248 Legionella Species 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 206010060862 Prostate cancer Diseases 0.000 description 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 229910004283 SiO 4 Inorganic materials 0.000 description 1
- 206010040904 Skin odour abnormal Diseases 0.000 description 1
- 206010040954 Skin wrinkling Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 244000062793 Sorghum vulgare Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 208000002495 Uterine Neoplasms Diseases 0.000 description 1
- 208000005735 Water intoxication Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000007059 acute toxicity Effects 0.000 description 1
- 231100000403 acute toxicity Toxicity 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000003905 agrochemical Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 229910021417 amorphous silicon Inorganic materials 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000001640 apoptogenic effect Effects 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 238000002619 cancer immunotherapy Methods 0.000 description 1
- 239000003575 carbonaceous material Substances 0.000 description 1
- 210000003855 cell nucleus Anatomy 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 239000013626 chemical specie Substances 0.000 description 1
- 239000003245 coal Substances 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 231100000517 death Toxicity 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 238000002296 dynamic light scattering Methods 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000006486 human diet Nutrition 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 150000002431 hydrogen Chemical class 0.000 description 1
- 230000009610 hypersensitivity Effects 0.000 description 1
- 208000034783 hypoesthesia Diseases 0.000 description 1
- 230000002631 hypothermal effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 208000028169 periodontal disease Diseases 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229910021420 polycrystalline silicon Inorganic materials 0.000 description 1
- 235000012015 potatoes Nutrition 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000001226 reprecipitation Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 125000005624 silicic acid group Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 208000009852 uremia Diseases 0.000 description 1
- 206010046766 uterine cancer Diseases 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B33/00—Silicon; Compounds thereof
- C01B33/113—Silicon oxides; Hydrates thereof
- C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
- C01B33/14—Colloidal silica, e.g. dispersions, gels, sols
- C01B33/141—Preparation of hydrosols or aqueous dispersions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Non-Alcoholic Beverages (AREA)
- Silicon Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023191562A JP2024023263A (ja) | 2019-02-19 | 2023-11-09 | 水溶性ナノコロイドシリカの製造方法、及び水溶性ナノコロイドシリカ |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019027411 | 2019-02-19 | ||
| JP2019027411 | 2019-02-19 | ||
| PCT/JP2020/006600 WO2020171132A1 (ja) | 2019-02-19 | 2020-02-19 | 水溶性ナノコロイドシリカの製造方法、及び水溶性ナノコロイドシリカ |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023191562A Division JP2024023263A (ja) | 2019-02-19 | 2023-11-09 | 水溶性ナノコロイドシリカの製造方法、及び水溶性ナノコロイドシリカ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2020171132A1 JPWO2020171132A1 (https=) | 2020-08-27 |
| JP7388750B2 true JP7388750B2 (ja) | 2023-11-29 |
Family
ID=72143687
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021502100A Active JP7388750B2 (ja) | 2019-02-19 | 2020-02-19 | 動植物摂取用水溶性ナノコロイドシリカの製造方法、及び動植物摂取用水溶性ナノコロイドシリカ |
| JP2023191562A Pending JP2024023263A (ja) | 2019-02-19 | 2023-11-09 | 水溶性ナノコロイドシリカの製造方法、及び水溶性ナノコロイドシリカ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023191562A Pending JP2024023263A (ja) | 2019-02-19 | 2023-11-09 | 水溶性ナノコロイドシリカの製造方法、及び水溶性ナノコロイドシリカ |
Country Status (2)
| Country | Link |
|---|---|
| JP (2) | JP7388750B2 (https=) |
| WO (1) | WO2020171132A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7348681B1 (ja) | 2022-04-04 | 2023-09-21 | 株式会社 life park. biz | 水溶性ケイ素溶液の製造方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008072637A1 (ja) | 2006-12-12 | 2008-06-19 | Fuso Chemical Co. Ltd. | コロイダルシリカの製造方法 |
| JP2010506814A (ja) | 2006-10-20 | 2010-03-04 | エボニック デグサ ゲーエムベーハー | 安定性を有する水性シリカ分散液 |
| JP2010052951A (ja) | 2008-08-26 | 2010-03-11 | Central Glass Co Ltd | シリコンの製造方法 |
| JP2011225381A (ja) | 2010-04-15 | 2011-11-10 | Furukawa Electric Co Ltd:The | 表層制御積層シリカナノ粒子及びその製造方法 |
| JP2014208585A (ja) | 2013-03-29 | 2014-11-06 | 株式会社アドマテックス | シリカ粒子、シリカ粒子の製造方法、及び、表面改質シリカ粒子の製造方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2614995A (en) * | 1951-06-13 | 1952-10-21 | Du Pont | Silica sols and preparation thereof from metallic silicon |
| US4309216A (en) * | 1980-03-26 | 1982-01-05 | Union Carbide Corporation | Low density compacts of prepared mix for use in the production of silicon and ferrosilicon |
| JPS61117110A (ja) * | 1984-11-07 | 1986-06-04 | Kawasaki Steel Corp | 金属珪素の製造方法ならびにその製造装置 |
| WO2014052911A1 (en) * | 2012-09-28 | 2014-04-03 | The Regents Of The University Of California | Degradable silica nanoshells for ultrasonic imaging/therapy |
| JP6687933B2 (ja) * | 2015-03-23 | 2020-04-28 | 国立研究開発法人物質・材料研究機構 | 水溶性近赤外発光ナノ粒子の製造方法 |
| IL254053B (en) * | 2016-08-19 | 2021-03-25 | Univ Nat Taiwan | Nanoparticles of hollow silica with thermalized biologically active components, a process for their preparation and their applications |
-
2020
- 2020-02-19 WO PCT/JP2020/006600 patent/WO2020171132A1/ja not_active Ceased
- 2020-02-19 JP JP2021502100A patent/JP7388750B2/ja active Active
-
2023
- 2023-11-09 JP JP2023191562A patent/JP2024023263A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010506814A (ja) | 2006-10-20 | 2010-03-04 | エボニック デグサ ゲーエムベーハー | 安定性を有する水性シリカ分散液 |
| WO2008072637A1 (ja) | 2006-12-12 | 2008-06-19 | Fuso Chemical Co. Ltd. | コロイダルシリカの製造方法 |
| JP2010052951A (ja) | 2008-08-26 | 2010-03-11 | Central Glass Co Ltd | シリコンの製造方法 |
| JP2011225381A (ja) | 2010-04-15 | 2011-11-10 | Furukawa Electric Co Ltd:The | 表層制御積層シリカナノ粒子及びその製造方法 |
| JP2014208585A (ja) | 2013-03-29 | 2014-11-06 | 株式会社アドマテックス | シリカ粒子、シリカ粒子の製造方法、及び、表面改質シリカ粒子の製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2020171132A1 (https=) | 2020-08-27 |
| WO2020171132A1 (ja) | 2020-08-27 |
| JP2024023263A (ja) | 2024-02-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7700404B2 (ja) | エクオール製造方法 | |
| TWI332009B (https=) | ||
| KR100993571B1 (ko) | 미네랄 함유수의 제조방법 및 이에 의해 제조된 미네랄 함유수 | |
| KR102207608B1 (ko) | 카르복실산으로 유기화된 규소 이온 복합체 및 복합체의 제조방법과 이를 이용한 제품 | |
| JP2024113015A (ja) | 水溶性ケイ素を含有する美容健康用組成物の製造方法および水溶性イオン化ケイ素の調整方法 | |
| JP6112308B2 (ja) | 苦味マスキング食材、及び苦味マスキング方法 | |
| JP2024023263A (ja) | 水溶性ナノコロイドシリカの製造方法、及び水溶性ナノコロイドシリカ | |
| KR101917180B1 (ko) | 규소 기반의 식품첨가물 제조 방법 | |
| CN102018158A (zh) | 一种芦荟果酱 | |
| Asouzu et al. | Rheology and acceptance of pap (Zea mays) enriched with Jatropha carcus leaves to improve iron status in children | |
| CN106954771A (zh) | 花粉保健饮料 | |
| KR101285973B1 (ko) | 녹색입홍합 된장 제조방법 | |
| CN101473983A (zh) | 一种菠萝、马尾藻复合饮料的生产方法 | |
| CN1916064B (zh) | 芦荟凝胶多糖干粉及制备方法和制剂 | |
| JP2013013390A (ja) | 苦味マスキング食材、及び苦味マスキング方法 | |
| JP7655524B2 (ja) | 機能性食用炭および水素パウダーの製造方法 | |
| KR102268307B1 (ko) | 진주에서 추출된 미네랄을 포함하는 음용수 및 이의 제조방법 | |
| CN100493362C (zh) | 木瓜籽奶饮料及其生产工艺 | |
| JP4960591B2 (ja) | マンノオリゴ糖類を含有する抗アレルゲン組成物 | |
| CN109288041A (zh) | 一种辣木复合液体制剂及制备方法 | |
| JP2012528586A (ja) | ゼオライト含有食品 | |
| JP5668018B2 (ja) | アルコール摂取障害予防剤 | |
| RU2482698C1 (ru) | Состав для приготовления безалкогольного желейного напитка | |
| JP4694547B2 (ja) | パパイア果実発酵物及びパパイア加工食品 | |
| KR20130010238A (ko) | 해초 알카리 농축액의 제조방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20211216 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20221208 |
|
| A871 | Explanation of circumstances concerning accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A871 Effective date: 20221208 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20230228 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230406 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20230627 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230822 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20231010 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20231109 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 7388750 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |