JP6911845B2 - Oral composition - Google Patents

Description

The present invention relates to an oral composition having excellent oral retention of tocopherol or a derivative thereof.

Tocopherol or a derivative thereof (vitamin E) is a component effective in the prevention and treatment of gingitis and periodontitis, and its excellent oral retention is considered to be useful in terms of the manifestation of the effect. In the oral composition, it has been difficult to sufficiently and satisfactorily retain tocopherol or a derivative thereof, which is an oil-soluble component and has a problem in stability, in the oral cavity where saliva is constantly secreted.

In Patent Document 1 (Patent No. 5682235), foaming performance is improved by blending xanthan gum, an alkyl sulfate, and an amphoteric surfactant in a toothpaste composition containing an oil-soluble component, and the oil-soluble component stays in the oral cavity. However, as a result of further studies on the improvement of the oral retention of vitamin E, the present inventors have found that the oral retention of vitamin E is particularly high when the amount of vitamin E is large. There was room for improvement.
Further, regarding the improvement of the stability of tocopherol or its derivative in the oral composition, Patent Document 2 (Japanese Patent Publication No. 7-88292) specifies the storage stability of tocopherol or its derivative in the presence of an alkyl sulfate ester salt. Improvement by amino acids, Patent Document 3 (Japanese Patent No. 4496429) describes a dentin composition containing vitamin E or a derivative thereof and an anionic surfactant, which is a composition of vitamin E or a derivative thereof in a container. Stability is maintained by a particular nonionic surfactant mixture, and Patent Document 4 (Japanese Patent Laid-Open No. 2015-110664) states that vitamin E or a derivative thereof is preserved together with ascorbic acid phosphate ester or a salt thereof. Although it has been disclosed that stability is improved by a specific nonionic surfactant, the oral retention of tocopherol or a derivative thereof has not been investigated and is not mentioned.

Japanese Patent No. 5682235 Special Fair 7-88292 Japanese Patent No. 4494629 JP-A-2015-110664

Therefore, in the oral composition, it has been a problem to improve the retention in the oral cavity of tocopherol or a derivative thereof.

The present invention has been made in view of the above circumstances, and an oral composition having excellent oral retention of tocopherol or a derivative thereof, excellent extrudability of a pharmaceutical product from a container, and good usability (spinnability). The purpose is to provide.

As a result of diligent studies to achieve the above object, the present inventors have identified both xanthan gum and carrageenan and a specific anionic surfactant in an oral composition containing tocopherol or a derivative thereof. It was found that by blending in an amount, the retention in the oral cavity of tocopherol or a derivative thereof is improved, the extrudability of the preparation from the container is excellent, and the usability is also good. That is, according to the present invention, one or more anionic surfactants selected from (A) tocopherol or a derivative thereof, (B) xanthan gum and carrageenan, (C) acylamino acid, acyltaurine and salts thereof. In the oral cavity of the component (A), the content of the component (B) is 1.2 to 3% by mass, and the content of the component (C) is 0.1 to 3% by mass. It has excellent retention and gives excellent extrudability that gives an appropriate hardness that allows the formulation to be extruded smoothly from the container, and gives good usability with good kneading (spinning property) when placed on a toothbrush. It was discovered that this can also be done, and the present invention was made.

More specifically, in the present invention, when the component (B) and the component (C) are combined with the component (A), the oral retention of the component (A) is determined by the combined system of the components (B) and (C). It is significantly improved and gives a special effect that cannot be achieved by adding an inappropriate binder or an inappropriate anionic surfactant. In this case, the use of xanthan gum or carrageenan alone does not satisfactorily improve the retention in the oral cavity of component (A), and the use of xanthan gum alone does not allow it to be kneaded (spinnable) when placed on a toothbrush. The properties were also inferior, and when both xanthan gum and carrageenan were mixed and used, the extrudability from the container of the preparation became hard after storage, which was a problem that did not occur when xanthan gum or carrageenan was used alone. On the other hand, by using the component (C) in combination with the component (B), the amount of the component (A) retained in the oral cavity can be increased without causing the above-mentioned problems related to usability such as extrudability and spinnability. It increased, and as shown in Examples described later, it was possible to impart excellent oral retention, in which most of the component (A) remains even after being applied to a gingival model and washed with water multiple times.

Therefore, the present invention
(A) Tocopherol or a derivative thereof,
(B) Xanthan gum and carrageenan,
(C) Contains one or more anionic surfactants selected from acyl amino acids, acyl taurine and salts thereof, and the content of the component (B) is 1.2 to 3% by mass, (C). Provided is an oral composition characterized in that the content of the component is 0.1 to 3% by mass.

According to the present invention, it is possible to provide an oral composition having excellent oral retention of tocopherol or a derivative thereof, excellent extrudability of a pharmaceutical product from a container, and good usability such as spinnability. Furthermore, even in the oral cavity where saliva is constantly secreted, the component (A) can be satisfactorily retained, and prevention of gingitis and periodontitis and improvement of therapeutic effect can be expected, and for prevention or suppression of periodontal disease. Is suitable as.

Hereinafter, the present invention will be described in more detail. The oral composition of the present invention contains (A) tocopherol or a derivative thereof, (B) xanthan gum and carrageenan, (C) acylamino acid, acyltaurine and an anionic surfactant selected from salts thereof as essential components. ..

(A) Tocopherol or a derivative thereof has a blood circulation promoting action and is a component for preventing or suppressing gingival inflammation and periodontitis.
Examples of tocopherol or a derivative thereof include d-α-tocopherol, dl-α-tocopherol, β-tocopherol, γ-tocopherol, δ-tocopherol, and organic acids such as acetic acid, nicotinic acid, succinic acid, and linolenic acid. Esters, salts of these and the like. Specifically, such tocopherol derivatives include d-α-tocopherol acetate, dl-α-tocopherol acetate, d-α-tocopherol nicotinate, dl-α-tocopherol nicotinate, d-α-tocopherol succinate, and succinate. Examples thereof include dl-α-tocopherol acid, d-α-tocopherol linolenate, dl-α-tocopherol linolenate, and tocopherol calcium succinate. These may be used alone or in combination of two or more, and among them, dl-α-tocopherol, dl-α-tocopherol acetate, dl-α-tocopherol nicotinate, particularly dl-α-tocopherol acetate are the appearance (color tone) of the preparation. Is preferable in that

As tocopherol or a derivative thereof, a product conforming to the old cosmetic raw material standard (cosmetic raw material group) or quasi-drug raw material standard 2006 can be used, and is manufactured by DSM Nutrition Japan, Eisai Food & Chemical, BASF Japan, etc. Commercial products can be used.

The blending amount of the component (A) is 0.1% (mass%, the same applies hereinafter) or more, preferably 0.1 to 2%, more preferably 0.2 to 2%, and even more preferably 0. .3 to 1.5%, particularly preferably 0.5 to 1.5%. The larger the blending amount, the more effectively the medicinal effect is exhibited, but if the blending amount is too large, there is a possibility that problems may occur in terms of pharmaceutical characteristics and the like.

The component (B) is a mixture of xanthan gum and carrageenan, and when both are used in combination, the retention in the oral cavity of the component (A) is improved. When xanthan gum or carrageenan is used alone, the retention in the oral cavity is inferior.

The xanthan gum may be any one as long as it is usually used in a dentifrice composition, but the viscosity of the xanthan gum is 600 to 2,000 mPa · s with a viscosity of a 1% aqueous solution of xanthan gum containing 1% potassium chloride. The one is preferable, and the one of 1,000 to 2,000 mPa · s is particularly preferable.
The above viscosities are based on the Brookfield type rotational viscometer, rotor No. It is a value at 3, 60 rpm, 25 ° C., and a measurement time of 30 seconds.
As such xanthan gum, commercially available products such as Novazan manufactured by ADM Far East Co., Ltd., Monato gum DA manufactured by CP Kelco Co., Ltd., Kelzan T, Keldent, Echo gum manufactured by Dainippon Pharmaceutical Co., Ltd., and the like can be used.

Examples of carrageenan include κ (kappa) -carrageenan, ι (iota) -carrageenan, and λ (lambda) -carrageenan, and one or more types can be used, but ι (iota) -carrageenan should be preferably used. Can be done. Examples of ι-carrageenan include GENUVISCO manufactured by CP Kerco.

The total amount of the component (B), xanthan gum and carrageenan, is 1.2% or more, particularly preferably 1.2 to 3%, and more preferably 1.4 to 2.5% of the total composition. The larger the blending amount, the higher the retention in the oral cavity of the component (A), and if it is less than 1.2%, the retention in the oral cavity is inferior. The larger the blending amount, the higher the retention in the oral cavity, but in order to maintain good extrudability of the preparation, it is preferably 3% or less.
Further, within the range of the above total blending amount, the blending amount of xanthan gum is preferably 0.6 to 2.8%, more preferably 0.9 to 2.1% of the entire composition, and the blending amount of carrageenan is It is preferably 0.2 to 2.4%, more preferably 0.4 to 1.6% of the total composition.

The mass ratio of xanthan gum / carrageenan, which indicates the mixing ratio of xanthan gum and carrageenan, is preferably 0.5 to 5, and more preferably 1 to 3. Within this range, the retention in the oral cavity of the component (A) is more excellent, and the spinnability is further improved. If it is less than 0.5, the retention in the oral cavity may not be sufficiently improved, and if it exceeds 5, the spinnability may be increased.

The anionic surfactant of the component (C) is one or more selected from acyl amino acids, acyl taurine and salts thereof.

As the acyl amino acid, those having an acyl group having 8 to 20 carbon atoms, particularly 12 to 16 are preferable, and the amino acid residues are glutamate, aspartic acid, glycine, sarcosin, alanine, methionine, phenylalanine and leucine. , Isoleucine and the like. Examples of the salt include alkali metal salts such as sodium salt and potassium salt, alkaline earth metal salts, organic amine salts and the like.
As the acyl amino acid and its salt, an acylglutamate having an acyl group having the above-mentioned carbon number, an acylaspartate, an acylglycine salt, particularly an acylglutamate, particularly sodium lauroyl glutamate, has a different taste than those having other amino acid residues. (Bitter taste) is weak and suitable.
Examples of the acyl amino acid salt include acyl glutamates such as sodium N-lauroyl-L-glutamate, sodium N-myristoyl-L-glutamate, and potassium N-palm fatty acid acyl-L-glutamate, and N-lauroyl-L-aspartic acid. Examples thereof include acyl aspartate such as sodium and acyl glycine salts such as N-palm oil fatty acid acyl glycine potassium.

Specific examples of the acyl amino acid and its salt include aminosurfact ALMS-P1 (N-lauroyl-L-monosodium glutamate, Asahi Kasei Chemicals Co., Ltd.), Amisoft LS-11 (N-lauroyl-L-monosodium glutamate, Ajinomoto Healthy). Supply Co., Ltd.), Amino Surfact AMMS-P1 (N-Millistoyl-L-sodium glutamate, Asahi Kasei Chemicals Co., Ltd.), Amisoft MS-11 (N-Millistoyl-L-sodium glutamate, Ajinomoto Healthy Supply Co., Ltd.), Amino Four Commercialized under trade names such as Mar FLDS-L (N-lauroyl-L-sodium aspartate, Asahi Kasei Chemicals Co., Ltd.), Amylite GCK-12K (N-palm oil amino acid acylglycine potassium, Ajinomoto Healthy Supply Co., Ltd.) You can use what you have.

The acyl taurine preferably has an acyl group having 8 to 20 carbon atoms, particularly 12 to 16, and the taurine residue is taurine, methyl taurine, or the like. Examples of the salt include alkali metal salts such as sodium salt and potassium salt.
Specific examples of the acyl taurine salt include cocoyl methyl taurine sodium, cocoyl methyl taurine potassium, lauroyl methyl taurine sodium, stearoyl methyl taurine sodium, myristoyl methyl taurine sodium, oleoyl methyl taurine sodium, palmitoyl methyl taurine sodium, and cocoyl taurine sodium. Be done.
Of these, acylmethyltaurine salts, especially sodium lauroylmethyltaurine, are preferred.

As the component (C), one selected from acyl amino acids, acyl taurine and salts thereof may be used alone, or two or more thereof may be used in combination, but in particular, the acyl taurine salt may be used in terms of extrudability. Is preferable.

The blending amount of the component (C) is 0.1 to 3%, preferably 0.3 to 1.5% of the total composition. If the blending amount is less than 0.1%, the oral retention of the component (A) is not sufficiently improved, and the pharmaceutical product is difficult to extrude from the container after storage, resulting in poor extrudability. The larger the amount, the better the retention in the oral cavity and the extrudability, but if it exceeds 3%, bitterness and irritation occur, and the stability of the component (A) decreases.

Further, (B) / (C) indicating the blending ratio of the component (B) and the component (C) is preferably 0.5 to 10 as a mass ratio, more preferably 1 to 8, and particularly preferably 1.2. ~ 6. Within this range, the retention in the oral cavity is more excellent, and the extrudability and the spinnability are further improved.

The anionic surfactant other than the component (C) can be blended within a range that does not interfere with the effect of the present invention, but is preferably 50% or less, preferably 20% or less of the total amount of the anionic surfactant. ..

The oral composition of the present invention can be prepared in the form of liquid, liquid, gel, paste, etc. in the form of dentifrices such as dentifrices, liquid dentifrices, liquid dentifrices, and gargles, and mouthwashes. However, dentifrices are particularly suitable. In this case, in addition to the above-mentioned components according to the purpose, dosage form and the like of the composition, other known components may be blended as necessary and prepared by a conventional method. For example, in the case of dentifrices, abrasives, binders, thickeners, surfactants, sweeteners, colorants, preservatives, pH adjusters, fragrances, active ingredients and the like can be mentioned.

Examples of the polishing agent include silica-based abrasives such as precipitated silica, aluminosilicate and zirconosilicate, calcium dibasic phosphate / dihydrate and anhydrous, calcium phosphate-based compounds such as calcium primary phosphate and calcium tertiary phosphate, and calcium carbonate. , Calcium hydroxide, aluminum hydroxide and the like. The blending amount of the abrasive is usually 2 to 40%, preferably 10% or less, more preferably 5% or less, and may be non-blended (0%).
In the oral composition, it is preferable to reduce the number of times of rinsing with water after use in order to retain the medicinal component in the oral cavity. Also in the present invention, water-insoluble powder, particularly silica-based polishing, is performed from the viewpoint of easiness of rinsing. It is preferable that the amount of abrasive such as an agent is small. The composition of the present invention is more preferably a dentifrice containing no abrasive (abrasive amount 0%) and having a gel composition, particularly an aqueous gel composition.

As the binder, a binder other than xanthan gum and carrageenan can be blended as long as the effects of the present invention are not impaired. Specifically, thickening silica such as gelling silica as an inorganic binder, cellulose derivatives such as sodium carboxymethyl cellulose, methyl cellulose and hydroxymethyl cellulose as organic binders, alginate derivatives such as sodium alginate, sodium polyacrylate and the like. In particular, an inorganic binder such as thickening silica is preferable in terms of retention feeling, appearance (moldability), and extrudability.
The blending amount of these binders is preferably 0.5 to 10%, particularly preferably 1 to 8%.
The amount of the organic binder other than the component (B) should be 0.2% or less, particularly 0.1% or less, in terms of the retention in the oral cavity of the component (A) and the extrudability of the preparation. Is preferable, and it is also preferable that the compound is not blended (0%).

Examples of the thickener include sugar alcohols such as sorbitol and xylit, and polyhydric alcohols such as glycerin and propylene glycol. The blending amount is usually 5 to 50%, particularly 20 to 45%.

As a surfactant, in addition to the above-mentioned anionic surfactant, as a nonionic surfactant, a sugar fatty acid ester such as sucrose fatty acid ester, a sugar alcohol fatty acid ester, a sorbitan fatty acid ester, a glycerin fatty acid ester, and a polyglycerin fatty acid ester. , Polyoxyethylene sorbitan fatty acid ester, polyoxyethylene fatty acid ester such as polyoxyethylene hydrogenated castor oil, polyoxyethylene higher alcohol ether such as polyoxyethylene lauryl ether, and the like can be blended.
Further, a cationic surfactant such as an alkylammonium type such as distearylmethylammonium chloride and an amphoteric surfactant such as a betaine type, a betaine acetate type and an imidazoline type can also be blended.
The blending amount of these surfactants is usually 0.01 to 10%, particularly 0.1 to 5%.

Examples of the sweetening agent include sodium saccharin and the like. Examples of the colorant include Blue No. 1, Yellow No. 4, Titanium Dioxide and the like.
Examples of the preservative include paraoxybenzoic acid esters such as methyl paraoxybenzoate, benzoic acid such as sodium benzoate, or salts thereof.
Further, a pH adjuster may be added, and examples thereof include alkali metal hydroxides such as sodium hydroxide, hydrogen carbonates, carbonates and sulfates.

Fragrances include peppermint oil, sparemint oil, anis oil, eucalyptus oil, winter green oil, cassia oil, clove oil, thyme oil, sage oil, lemon oil, orange oil, peppermint oil, cardamon oil, coriander oil, mandarin oil, Lime oil, lavender oil, rosemary oil, laurel oil, camomill oil, caraway oil, majorum oil, bay oil, lemongrass oil, origanum oil, pine needle oil, neroli oil, rose oil, jasmine oil, grapefruit oil, sweetie Natural fragrances such as oil, yuzu oil, iris concrete, absolute peppermint, absolute rose, orange flower, and processing of these natural fragrances (front reservoir cut, rear reservoir cut, distilling, liquid extraction, essence, powder Fragrances (such as fragrances) and menthol, carboxylic, anator, cineole, methyl salicylate, synamic aldehyde, eugenol, 3-l-mentoxypropane-1,2-diol, timol, linalol, linaryl acetate, limonene, Menton, Menthylacetate, N-Substituted-Peppermint-3-Carboxamide, Pinen, Octylaldehyde, Citral, Pregon, Calvia Acetate, Anisaldehyde, Ethylacetate, Ethylbutyrate, Allylcyclohexanepropionate, Methylanthranilate, Ethyl Single flavors such as methylphenylglycidate, vanillin, undecalactone, hexanal, butanol, isoamyl alcohol, hexenol, dimethylsulfide, cycloten, furfural, trimethylpyrazine, ethyllactate, ethylthioacetate, as well as strawberry flavor, apple flavor, banana Known flavoring materials used in oral compositions can be used in combination, such as flavors, pineapple flavors, grape flavors, mango flavors, butter flavors, milk flavors, fruit mix flavors, tropical fruit flavors and other blended flavors. , The fragrance is not limited to the fragrances described in the examples.
Further, the blending amount is not particularly limited, but it is preferable to use 0.000001 to 1% of the above-mentioned fragrance material in the composition. Further, as a perfume for perfume using the above perfume material, it is preferable to use 0.1 to 2% in the composition.

As the active ingredient, in addition to the ingredient (A), other medicinal ingredients can be blended, specifically, a nonionic bactericide such as isopropylmethylphenol, and cations such as cetylpyridinium chloride, benzalkonium chloride, and benzethonium chloride. Examples thereof include sex bactericides, anti-inflammatory agents, enzymes such as dextranase, fluorides such as sodium fluoride and sodium monofluorophosphate, vitamins, anti-dental agents, anti-plaque agents and the like. The active ingredient can be blended in an effective amount within a range that does not interfere with the effects of the present invention.

Hereinafter, the present invention will be specifically described with reference to Examples, Comparative Examples, and Formulation Examples, but the present invention is not limited to the following Examples. In the following examples,% indicates mass% unless otherwise specified.

[Examples, comparative examples]
The dentifrice compositions having the compositions shown in Tables 1 to 3 were prepared by the following methods and evaluated by the following methods. The results are also shown in the table.
Production method: After blending a water-soluble component in purified water, the component (B) dispersed in propylene glycol is added and mixed, and then the fragrance, the component (A), and the component (C) are sequentially added and defoamed and mixed. Made.
The xanthan gum used had a viscosity of a 1% aqueous solution of xanthan gum containing 1% potassium chloride (Brookfield type rotational viscometer, rotor No. 3, 60 rpm, 25 ° C., measurement time 30 seconds) at about 1,500 mPa · s. Yes, carrageenan is ι-carrageenan.

<Evaluation method of oral retention>
40 μL of a dentifrice diluent obtained by diluting the dentifrice composition 3-fold with water was placed on a hamster teak pouch (manufactured by Nippon SLC Co., Ltd., 3 weeks old ♂ Syrian) punched out to a diameter of 10 mm. After allowing to stand for 3 minutes, the mixture was washed 7 times with water, extracted with 1 mL of ethanol, and the oil-soluble component tocopherol or a derivative thereof was quantified by the following method by liquid chromatography.
The measurement conditions were a column in which a stainless steel tube having an inner diameter of 4.6 mm and a length of 15 cm was filled with 5 μm octadecylsilylated silica gel for liquid chromatography, and methanol was used as the mobile phase, and the column temperature was 25 ° C. and 1.0 mL / min. It was measured by the absolute calibration curve method at the ultraviolet absorptiometry (measurement wavelength 284 nm).
For the amount of tocopherol or its derivative retained in the oral cavity, the average value was repeatedly calculated three times, and the ratio of the residual amount to the initial value amount (the amount of tocopherol or its derivative contained in 40 μL of the first treated 3-fold diluted solution) was calculated. It was calculated and evaluated according to the following criteria.
Evaluation criteria ⊚: Retention amount is 30% or more ○: Retention amount is 20% or more and less than 30% Δ: Retention amount is 10% or more and less than 20% ×: Retention amount is less than 10%

<Evaluation method of extrudability>
50 g of the dentifrice composition is filled in a laminated tube container having a diameter of 8 mm, and after storing 3 of each composition at -5 ° C for 1 month, the dentifrice composition is extruded and the degree of extruded hardness is determined in the following 4 steps. evaluated.
Evaluation Criteria ◎: The dentifrice composition can be extruded smoothly ○: Slightly hard but the dentifrice composition can be extruded without problems △: Hard and the dentifrice composition is slightly difficult to extrude ×: Hard and the dentifrice composition is difficult to extrude

<Evaluation method of spinnability>
A laminated tube container having a diameter of 8 mm was filled with a dentifrice composition, and about 1 g of the dentifrice composition was placed on the toothbrush from the tube. The spinnability refers to the property that the dentifrice composition stretches like a string when taken out from the tube, and the length thereof is measured. It was evaluated according to the following criteria.
Evaluation criteria ◎: Spinning property is less than 0.5 cm and kneading is good ○: Spinning property of 0.5 cm or more and less than 1 cm is observed, but there is no problem in use Δ: 1 cm or more and less than 1.5 cm Spinning property is recognized and there is some problem in use. ×: Spinning property of 1.5 cm or more is recognized and there is a problem in use.

[Prescription Example 1] Toothpaste (A) Tocopherol acetate 1.0%
(B) Xanthan gum 1.5
(B) Carrageenan 0.5
(C) Sodium lauroylmethyl taurine 1.0
Abrasive silica 10
Viscous silica 5
70% sorbitol liquid 40
Saccharin sodium 0.2
Isopropylmethylphenol 0.1
Sodium fluoride 0.21
Polyoxyethylene (20) hardened castor oil 1.2
Polyoxyethylene (5) Stearyl Ether 1.2
Propylene glycol 3
Sodium hydroxide 0.1
Sodium dihydrogen phosphate 0.1
Fragrance 0.8
Purified water balance
Total 100.0%
Xanthan gum / carrageenan ratio; 3 (B) / (C); 2

Claims (11)

(A) Tocopherol or a derivative thereof,
It contains (B) xanthan gum and carrageenan, and (C) one or more anionic surfactants selected from acyl amino acids, acyl taurine and salts thereof, and the content of (B) component is 1.2. An oral composition having a content of ~ 3% by mass and the content of the component (C) of 0.1 to 3% by mass. The oral composition according to claim 1, wherein the content mass ratio of xanthan gum and carrageenan represented by xanthan gum / carrageenan is 0.5 to 5. The oral composition according to claim 1 or 2, wherein the content of xanthan gum is 0.6 to 2.8% by mass and the content of carrageenan is 0.2 to 2.4% by mass. The component (C) is an acyl glutamate, an acyl aspartate and an acyl glycine salt having an acyl group having 8 to 20 carbon atoms, and an acyl taurine salt and an acyl methyl taurine salt having an acyl group having 8 to 20 carbon atoms. The oral composition according to any one of claims 1 to 3, which is one or more anionic surfactants selected from the above. The oral composition according to any one of claims 1 to 4, wherein the amount of the anionic surfactant other than the component (C) is 50% by mass or less of the total amount of the anionic surfactant. The oral composition according to any one of claims 1 to 5 , wherein the content mass ratio of the component (B) represented by (B) / (C) to the component (C) is 0.5 to 10. .. The oral composition according to any one of claims 1 to 6 , wherein the content of the component (A) is 0.1 to 2% by mass. The oral composition according to any one of claims 1 to 7 , further comprising 10% by mass of an abrasive. The oral composition according to any one of claims 1 to 8 , which does not contain an abrasive. The oral composition according to any one of claims 1 to 9 , further comprising 0.5 to 10% by mass of an inorganic binder. The oral composition according to any one of claims 1 to 10 , which is a dentifrice.