JP6893914B2 - 光開裂可能標識を使用する抗原検出の方法 - Google Patents

光開裂可能標識を使用する抗原検出の方法 Download PDF

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JP6893914B2
JP6893914B2 JP2018506118A JP2018506118A JP6893914B2 JP 6893914 B2 JP6893914 B2 JP 6893914B2 JP 2018506118 A JP2018506118 A JP 2018506118A JP 2018506118 A JP2018506118 A JP 2018506118A JP 6893914 B2 JP6893914 B2 JP 6893914B2
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antigen
ligand
binding complex
photocleavable
sample
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JP2018523826A5 (https=
JP2018523826A (ja
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ミミ ヘアリー
ミミ ヘアリー
チーイー チェン
チーイー チェン
ジンチュン ワン
ジンチュン ワン
ウェイドン ウ
ウェイドン ウ
ソフィア ペトリチェンコ
ソフィア ペトリチェンコ
ス チャン
ス チャン
ステイシー フライ
ステイシー フライ
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Agilent Technologies Inc
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Agilent Technologies Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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    • G01—MEASURING; TESTING
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/302—Stain compositions
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    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00138—Slides
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/10—Oligonucleotides as tagging agents for labelling antibodies

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  • Immunology (AREA)
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  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Clinical Laboratory Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2018506118A 2015-08-06 2016-08-08 光開裂可能標識を使用する抗原検出の方法 Active JP6893914B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562201978P 2015-08-06 2015-08-06
US62/201,978 2015-08-06
PCT/US2016/045981 WO2017024298A1 (en) 2015-08-06 2016-08-08 Antigen detection using photocleavable labels

Publications (3)

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JP2018523826A JP2018523826A (ja) 2018-08-23
JP2018523826A5 JP2018523826A5 (https=) 2019-10-17
JP6893914B2 true JP6893914B2 (ja) 2021-06-23

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US (2) US10942176B2 (https=)
EP (1) EP3332253A1 (https=)
JP (1) JP6893914B2 (https=)
CN (1) CN107949790B (https=)
AU (2) AU2016304599A1 (https=)
BR (1) BR112018002525A2 (https=)
CA (2) CA3138794C (https=)
MX (1) MX2018001519A (https=)
WO (1) WO2017024298A1 (https=)

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EP3431173A1 (en) * 2017-07-19 2019-01-23 Bayer Pharma Aktiengesellschaft Continuous manufacture of guidance molecule drug conjugates
JP2021511799A (ja) * 2018-01-30 2021-05-13 ラッシュ ユニヴァーシティ メディカル センター 組織および細胞の多重分析のための連続染色
WO2019236522A1 (en) * 2018-06-04 2019-12-12 Dana-Farber Cancer Institute, Inc. Compositions and methods for targeted immunotherapy
CA3125920A1 (en) 2019-01-07 2020-07-16 Agilent Technologies, Inc. Compositions and methods for genomic dna and gene expression analysis in single cells
JP2020143015A (ja) * 2019-03-06 2020-09-10 ソニー株式会社 粒子標識用試薬、粒子染色方法、及び顕微鏡システム
EP3983803A2 (en) * 2019-06-14 2022-04-20 Akoya Biosciences, Inc. Multiplexed tissue imaging
CN111381034A (zh) * 2020-03-03 2020-07-07 武汉生之源生物科技股份有限公司 一种gpc-3抗体包被磁珠及其制备方法、试剂盒
US20230390773A1 (en) * 2020-10-05 2023-12-07 Clara Biotech, Inc. Apparatus, system, and method for analyte release
CN112595845B (zh) * 2020-12-09 2022-10-21 深圳普门科技股份有限公司 透明质酸检测试剂盒及检测系统
CN121248767A (zh) * 2025-08-25 2026-01-02 北京科技大学 用于免疫共沉淀测序的含光裂解基团抗体、方法及试剂盒

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Publication number Publication date
AU2022210222B2 (en) 2025-09-18
EP3332253A1 (en) 2018-06-13
CA3138794A1 (en) 2017-02-09
CN107949790A (zh) 2018-04-20
WO2017024298A1 (en) 2017-02-09
CA2993993A1 (en) 2017-02-09
US20210181191A1 (en) 2021-06-17
CA3138794C (en) 2024-01-23
US20170052175A1 (en) 2017-02-23
US10942176B2 (en) 2021-03-09
BR112018002525A2 (pt) 2018-09-25
CN107949790B (zh) 2024-07-26
AU2022210222A1 (en) 2022-08-25
MX2018001519A (es) 2018-08-01
JP2018523826A (ja) 2018-08-23
CA2993993C (en) 2022-01-04
AU2016304599A1 (en) 2018-02-15

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