JP6275278B2 - 酸触媒の組合せ混合物を用いた糖アルコールの脱水 - Google Patents
酸触媒の組合せ混合物を用いた糖アルコールの脱水 Download PDFInfo
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- JP6275278B2 JP6275278B2 JP2016561354A JP2016561354A JP6275278B2 JP 6275278 B2 JP6275278 B2 JP 6275278B2 JP 2016561354 A JP2016561354 A JP 2016561354A JP 2016561354 A JP2016561354 A JP 2016561354A JP 6275278 B2 JP6275278 B2 JP 6275278B2
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- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/001—General concepts, e.g. reviews, relating to catalyst systems and methods of making them, the concept being defined by a common material or method/theory
- B01J2531/002—Materials
- B01J2531/007—Promoter-type Additives
Description
本出願は、各々の内容が参照により本明細書に組み込まれる、2014年4月10日に出願された国際出願第PCT/US2014/033580号および第PCT/US2014/033581号、ならびに2014年11月19日に出願された国際出願第PCT/US2014/66298号の優先権の利益を主張する。
本明細書に記載される方法の有利な特徴は、ソルビトールの脱水を用いて例証されるが、本方法は、様々な糖アルコールまたは糖アルコールの脱水生成化合物(例えば、ソルビトール、マンニトール、イジトール、キシリトール、および1,2,5,6−ヘキサンテトラオール(HTO))をそれらの脱水生成物の調製において変化させるために使用することができる。
図1〜20は、表1で概括されているデータをグラフ形式で示している。これらの図は、様々な反応条件(すなわち、温度および時間)の下、様々な触媒添加レベルのホスホン酸(H3PO3)触媒と、様々な触媒添加レベルの強いブレンステッド酸および/またはルイス酸触媒とを、単独で、ならびに強いブレンステッド酸および/またはルイス酸触媒と共に用いて、イソソルビドに変換されたソルビトールの百分率および生成物組成アカウンタビリティーの百分率を示している。
Claims (7)
- 環式脱水生成物を調製する方法であって、アルミニウムトリフルオロメタンスルホネート(Al(OTf) 3 )、ガリウムトリフルオロメタンスルホネート(Ga(OTf) 3 )、ビスマストリフルオロメタンスルホネート(Bi(OTf) 3 )、スカンジウムトリフルオロメタンスルホネート(Sc(OTf) 3 )、インジウムトリフルオロメタンスルホネート(In(OTf) 3 )、スズトリフレート(Sn(OTf) 2 )、およびハフニウムトリフレート(Hf(OTf) 4 )からなる群から選択されるルイス酸と一緒に、ホスホン酸(H 3 PO 3 )である還元性ブレンステッド酸を含有する混合酸触媒反応混合物に、糖アルコールをある温度で十分な時間接触させて、前記糖アルコールを脱水および閉環して生成混合物中で糖アルコールの対応する環式脱水生成物とすることを含む、方法。
- 前記糖アルコールが、ソルビトール、マンニトール、イジトール、キシリトール、エリスリトール、および1,2,5,6−ヘキサンテトラオール(HTO)のうちの少なくとも1つである、請求項1に記載の方法。
- 前記還元性ブレンステッド酸の、前記ルイス酸に対する比率が、1000:1〜5:1である、請求項1に記載の方法。
- 前記温度が120℃〜190℃である、請求項1に記載の方法。
- 前記還元性ブレンステッド酸が、前記糖アルコールに対して1.0mol.%〜20mol.%の濃度で存在する、請求項1に記載の方法。
- 前記還元性ブレンステッド酸が、前記糖アルコールに対して2mol.%〜15mol.%の濃度で存在する、請求項5に記載の方法。
- 前記ルイス酸が、前記糖アルコールに対して0.005mol.%〜0.5mol.%の濃度で存在する、請求項1に記載の方法。
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USPCT/US2014/033580 | 2014-04-10 | ||
PCT/US2014/033580 WO2015156802A1 (en) | 2014-04-10 | 2014-04-10 | Synthesis of reduced sugar alcohols, furan derivatives |
PCT/US2014/033581 WO2015156803A1 (en) | 2014-04-10 | 2014-04-10 | Synthesis of r-glucosides, sugar alcohols, reduced sugar alcohols, and furan derivatives of reduced sugar alcohols |
USPCT/US2014/033581 | 2014-04-10 | ||
PCT/US2014/066298 WO2015156839A1 (en) | 2014-04-10 | 2014-11-19 | Phosphonic acid catalyst in dehydrative cyclization of 5 and 6 carbon polyols with improved color and product accountability |
USPCT/US2014/066298 | 2014-11-19 | ||
PCT/US2014/070050 WO2015156846A1 (en) | 2014-04-10 | 2014-12-12 | Dehydration of a sugar alcohol with mixed combination of acid catalysts |
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JP2016561856A Pending JP2017513840A (ja) | 2014-04-10 | 2015-04-10 | より短鎖のポリオールの合成 |
JP2016561730A Pending JP2017515803A (ja) | 2014-04-10 | 2015-04-10 | 擬似移動床式クロマトグラフィーを使用して、1,2,5,6−ヘキサンテトラオールをソルビトール水素化分解反応混合物から単離するためのプロセス |
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JP2016561730A Pending JP2017515803A (ja) | 2014-04-10 | 2015-04-10 | 擬似移動床式クロマトグラフィーを使用して、1,2,5,6−ヘキサンテトラオールをソルビトール水素化分解反応混合物から単離するためのプロセス |
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