JP6265740B2 - アプリケータ - Google Patents

アプリケータ Download PDF

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Publication number
JP6265740B2
JP6265740B2 JP2013537516A JP2013537516A JP6265740B2 JP 6265740 B2 JP6265740 B2 JP 6265740B2 JP 2013537516 A JP2013537516 A JP 2013537516A JP 2013537516 A JP2013537516 A JP 2013537516A JP 6265740 B2 JP6265740 B2 JP 6265740B2
Authority
JP
Japan
Prior art keywords
piston
applicator
spring
microneedle array
transmission member
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2013537516A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2013051568A1 (ja
Inventor
誠治 徳本
誠治 徳本
小倉　誠
誠 小倉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Publication of JPWO2013051568A1 publication Critical patent/JPWO2013051568A1/ja
Application granted granted Critical
Publication of JP6265740B2 publication Critical patent/JP6265740B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
JP2013537516A 2011-10-06 2012-10-02 アプリケータ Active JP6265740B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011222236 2011-10-06
JP2011222236 2011-10-06
PCT/JP2012/075534 WO2013051568A1 (ja) 2011-10-06 2012-10-02 アプリケータ

Publications (2)

Publication Number Publication Date
JPWO2013051568A1 JPWO2013051568A1 (ja) 2015-03-30
JP6265740B2 true JP6265740B2 (ja) 2018-01-24

Family

ID=48043725

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013537516A Active JP6265740B2 (ja) 2011-10-06 2012-10-02 アプリケータ

Country Status (5)

Country Link
US (1) US9498611B2 (https=)
EP (1) EP2764887B1 (https=)
JP (1) JP6265740B2 (https=)
TW (1) TW201330893A (https=)
WO (1) WO2013051568A1 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
US9220678B2 (en) 2007-12-24 2015-12-29 The University Of Queensland Coating method
WO2012006677A1 (en) 2010-07-14 2012-01-19 The University Of Queensland Patch applying apparatus
WO2013053022A1 (en) 2011-10-12 2013-04-18 The University Of Queensland Delivery device
US20150057604A1 (en) * 2012-04-05 2015-02-26 Hisamitsu Pharmaceutical Co., Inc. Puncture Device and Method for Manufacturing Same
US9913970B2 (en) 2012-12-21 2018-03-13 Hisamitsu Pharmaceutical Co., Ltd. Applicator
EP2958533B8 (en) 2013-02-20 2022-02-16 Cytrellis Biosystems, Inc. Methods and devices for skin tightening
SG11201509722PA (en) 2013-05-31 2015-12-30 3M Innovative Properties Co Microneedle injection apparatus comprising a dual cover
EP3030175B1 (en) * 2013-08-09 2023-10-04 Cytrellis Biosystems, Inc. Apparatuses for skin treatment using non-thermal tissue ablation
WO2015040697A1 (ja) * 2013-09-18 2015-03-26 コスメディ製薬株式会社 マイクロニードルパッチ適用装置及びパッチホルダー
EP3067088B1 (en) 2013-11-05 2019-09-04 Hisamitsu Pharmaceutical Co., Inc. Applicator
KR102670286B1 (ko) 2014-11-14 2024-05-30 사이트렐리스 바이오시스템즈, 인크. 피부 절제를 위한 디바이스 및 방법
AU2016214968B2 (en) 2015-02-02 2021-02-25 Vaxxas Pty Limited Microprojection array applicator and method
JP2017023404A (ja) 2015-07-22 2017-02-02 日本写真印刷株式会社 マイクロニードルパッチ用インパクト付加型アプリケータ及び先端部材
WO2017038499A1 (ja) * 2015-09-02 2017-03-09 久光製薬株式会社 アプリケータ
WO2017045031A1 (en) 2015-09-18 2017-03-23 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
EP3355981B1 (en) 2015-09-28 2025-11-19 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
EP3606760B1 (en) 2017-03-31 2023-09-27 Vaxxas Pty Limited Device and method for coating surfaces
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
US11464957B2 (en) 2017-08-04 2022-10-11 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (MAP)
US10945759B2 (en) 2017-12-28 2021-03-16 Refine Usa, Llc Microneedle device
JP7099189B2 (ja) * 2018-08-30 2022-07-12 ニプロ株式会社 マイクロニードルアプリケータ
JP7172293B2 (ja) * 2018-08-30 2022-11-16 ニプロ株式会社 マイクロニードルアプリケータ
CN112888474A (zh) * 2018-08-30 2021-06-01 尼普洛株式会社 微针敷贴器
DE102019200557A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
US20220347451A1 (en) * 2020-01-09 2022-11-03 Industry-Academic Cooperation Foundation, Yonsei University Microneedle applicator
USD1023303S1 (en) * 2021-12-08 2024-04-16 Guangzhou Ekai Electronic Technology Co., Ltd. Microneedling pen
USD1031036S1 (en) * 2021-12-08 2024-06-11 Guangzhou Ekai Electronic Technology Co., Ltd. Microneedling pen
WO2025254172A1 (ja) * 2024-06-04 2025-12-11 花王株式会社 注射キット及び保持具
JP2025183186A (ja) * 2024-06-04 2025-12-16 花王株式会社 注射具及び注射キット

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1033099A (en) 1911-12-11 1912-07-23 John W Harrison Drill-socket.
US2932277A (en) 1957-10-28 1960-04-12 John E Borah Moistening device
US4526171A (en) 1980-01-15 1985-07-02 Schachar Ronald A Cornea incision device
US4589412A (en) 1984-01-03 1986-05-20 Intravascular Surgical Instruments, Inc. Method and apparatus for surgically removing remote deposits
US4747842A (en) 1987-06-22 1988-05-31 David Dietz Article for applying styptic to a dog's bleeding nail
US5026388A (en) 1989-09-26 1991-06-25 Ingalz Thomas J Single-use skin puncture device
CN1195299A (zh) 1996-05-18 1998-10-07 金振燮 艾灸器械
GB9817662D0 (en) 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
WO2001043643A1 (en) * 1999-12-16 2001-06-21 Alza Corporation Device for enhancing transdermal flux of sampled agents
KR200209938Y1 (ko) 2000-07-25 2001-01-15 변영광 화장품 용기
PL360998A1 (en) 2000-10-13 2004-09-20 Alza Corporation Apparatus and method for piercing skin with microprotrusions
PL360978A1 (en) 2000-10-13 2004-09-20 Alza Corporation Microblade array impact applicator
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
CA2425312C (en) 2000-10-13 2010-02-16 Alza Corporation Microprotrusion member retainer for impact applicator
US6945952B2 (en) 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
AU2003243750A1 (en) 2002-06-25 2004-01-06 Sung-Yun Kwon Rapidly dissolving micro-perforator for drug delivery and other applications
KR20120087197A (ko) 2002-07-19 2012-08-06 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로 니들 장치, 마이크로 니들 장치를 사용하는 방법 및 마이크로 니들 장치를 송출하는 방법
CA2543641A1 (en) * 2003-10-31 2005-05-19 Alza Corporation Self-actuating applicator for microprojection array
US20070083151A1 (en) 2003-12-29 2007-04-12 Carter Chad J Medical devices and kits including same
JP4832082B2 (ja) 2004-02-03 2011-12-07 久光製薬株式会社 経皮薬物投与装置用インタフェース
EP1773444B1 (en) 2004-06-10 2017-09-20 3M Innovative Properties Company Patch application device and kit
EP1790375A4 (en) 2004-08-12 2009-06-17 Hisamitsu Pharmaceutical Co TRANSDERMAL MEDICINE ADMINISTRATION WITH MICRONADEL
JP2008520367A (ja) 2004-11-18 2008-06-19 スリーエム イノベイティブ プロパティズ カンパニー 皮膚非接触型のマイクロニードルアレイアプリケータ
KR20130026511A (ko) 2004-11-18 2013-03-13 쓰리엠 이노베이티브 프로퍼티즈 컴파니 로우-프로파일 미세 바늘 어레이 인가 장치
WO2006069053A2 (en) 2004-12-22 2006-06-29 Charm Sciences, Inc. Sampling method and device
JP2006341089A (ja) 2005-05-13 2006-12-21 Fujikura Ltd 医薬物運搬用器具およびその製造方法
JP5000866B2 (ja) 2005-08-01 2012-08-15 久光製薬株式会社 生体無毒性医薬物運搬用器具
WO2007015441A1 (ja) 2005-08-01 2007-02-08 Hisamitsu Pharmaceutical Co., Inc. 経皮または経粘膜投与のためのアジュバントおよび製剤
ATE532553T1 (de) 2006-02-10 2011-11-15 Hisamitsu Pharmaceutical Co Transdermales arzneiverabreichungsgerät mit mikronadeln
CN101400320A (zh) 2006-03-10 2009-04-01 阿尔扎公司 采用高防渗定位器的微突起阵列应用
JP4963849B2 (ja) 2006-03-13 2012-06-27 シスメックス株式会社 微細孔形成システム
JP4908893B2 (ja) 2006-03-30 2012-04-04 久光製薬株式会社 医薬物運搬用器具とその製造方法及び医薬物運搬用器具製造用金型の製造方法
WO2007116959A1 (ja) 2006-04-07 2007-10-18 Hisamitsu Pharmaceutical Co., Inc. マイクロニードルデバイスおよびマイクロニードル付き経皮薬物投与装置
US20070293816A1 (en) 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
DK2054109T3 (en) 2006-08-24 2018-03-19 Hoffmann La Roche INTRODUCTION DEVICE FOR INTRODUCTION HEADS, ESPECIALLY FOR INFUSION KITS
AU2008209537B2 (en) 2007-01-22 2013-01-31 Corium Pharma Solutions, Inc. Applicators for microneedle arrays
US7381003B1 (en) 2007-01-24 2008-06-03 Chia-Sheng Chang Applicator of cosmetic cream jar
JP5275047B2 (ja) 2007-01-31 2013-08-28 久光製薬株式会社 経皮または経粘膜投与のためのアジュバントおよびこれを含む医薬製剤
JP5241517B2 (ja) 2007-02-06 2013-07-17 久光製薬株式会社 アレルギー診断用マイクロニードルデバイス
US8771781B2 (en) 2007-05-15 2014-07-08 Hisamitsu Pharmaceutical Co., Inc. Method of coating microneedle
WO2009051147A1 (ja) 2007-10-18 2009-04-23 Hisamitsu Pharmaceutical Co., Inc. マイクロニードルデバイス
USD598173S1 (en) 2008-06-13 2009-08-11 Hartel David D Tool for cleaning the outer surface of a tube
EP2327419B1 (en) 2008-06-30 2020-05-13 Hisamitsu Pharmaceutical Co., Inc. Microneedle device for enhancing the efficacy of influenza vaccine by using microneedle device
USD612939S1 (en) 2008-07-29 2010-03-30 Envy Medical, Inc. Microdermabrasion treatment tip mount
JP2010233803A (ja) 2009-03-31 2010-10-21 Sysmex Corp 微細孔形成用穿刺装置
WO2010143689A1 (ja) 2009-06-10 2010-12-16 久光製薬株式会社 マイクロニードルデバイス
WO2011010605A1 (ja) 2009-07-23 2011-01-27 久光製薬株式会社 マイクロニードルアレイ
JP2011078711A (ja) 2009-10-05 2011-04-21 Kosumedei Seiyaku Kk 磁力反発を利用したマイクロニードルアレイ投与装置
US20110172639A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Device and method for delivery of microneedle to desired depth within the skin
JP2011164723A (ja) 2010-02-04 2011-08-25 Tokai Rika Co Ltd 遠隔入力装置
US8911422B2 (en) 2010-02-24 2014-12-16 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device
SG183421A1 (en) * 2010-02-24 2012-09-27 Hisamitsu Pharmaceutical Co Micro-needle device and preparation method
EP2566568B1 (en) 2010-05-04 2019-04-10 Corium International, Inc. Applicators for microneedles
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
JP5562138B2 (ja) 2010-06-24 2014-07-30 シスメックス株式会社 微細孔形成装置
US20130226098A1 (en) 2010-10-07 2013-08-29 Hisamitsu Pharmaceutical Co., Inc. Applicator

Also Published As

Publication number Publication date
EP2764887A4 (en) 2015-12-09
EP2764887B1 (en) 2020-12-02
WO2013051568A1 (ja) 2013-04-11
TW201330893A (zh) 2013-08-01
US20140243747A1 (en) 2014-08-28
TWI561272B (https=) 2016-12-11
JPWO2013051568A1 (ja) 2015-03-30
US9498611B2 (en) 2016-11-22
EP2764887A1 (en) 2014-08-13

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