JP6078153B2 - チアンジンアミド誘導体、並びにその医薬組成物及び使用 - Google Patents

チアンジンアミド誘導体、並びにその医薬組成物及び使用 Download PDF

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JP6078153B2
JP6078153B2 JP2015527749A JP2015527749A JP6078153B2 JP 6078153 B2 JP6078153 B2 JP 6078153B2 JP 2015527749 A JP2015527749 A JP 2015527749A JP 2015527749 A JP2015527749 A JP 2015527749A JP 6078153 B2 JP6078153 B2 JP 6078153B2
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carbon atoms
branched alkyl
disease
linear
pharmaceutically acceptable
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JP2015526447A (ja
JP2015526447A5 (https=
Inventor
ソン リー
ソン リー
ジュインハイ シャオ
ジュインハイ シャオ
ダン ハン
ダン ハン
ウー ジョン
ウー ジョン
リリ ワン
リリ ワン
ジビーン ジュヨン
ジビーン ジュヨン
ユインデ シエ
ユインデ シエ
シンボ ジョウ
シンボ ジョウ
シーンジョウ リー
シーンジョウ リー
シャオクイ ワーン
シャオクイ ワーン
ダン ジアーン
ダン ジアーン
ウェイ チェン
ウェイ チェン
ホーンイーン リウ
ホーンイーン リウ
Original Assignee
インスティテュート オブ ファーマコロジー アンド トキシコロジー アカデミー オブ ミリタリー メディカル サイエンシズ ピー．エル．エー．チャイナ
インスティテュート オブ ファーマコロジー アンド トキシコロジー アカデミー オブ ミリタリー メディカル サイエンシズ ピー．エル．エー．チャイナ
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Application filed by インスティテュート オブ ファーマコロジー アンド トキシコロジー アカデミー オブ ミリタリー メディカル サイエンシズ ピー．エル．エー．チャイナ, インスティテュート オブ ファーマコロジー アンド トキシコロジー アカデミー オブ ミリタリー メディカル サイエンシズ ピー．エル．エー．チャイナ filed Critical インスティテュート オブ ファーマコロジー アンド トキシコロジー アカデミー オブ ミリタリー メディカル サイエンシズ ピー．エル．エー．チャイナ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
JP2015527749A 2012-08-24 2012-08-24 チアンジンアミド誘導体、並びにその医薬組成物及び使用 Active JP6078153B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2012/080539 WO2014029102A1 (zh) 2012-08-24 2012-08-24 噻嗪酰胺衍生物及其药物组合物和用途

Publications (3)

Publication Number Publication Date
JP2015526447A JP2015526447A (ja) 2015-09-10
JP2015526447A5 JP2015526447A5 (https=) 2015-10-29
JP6078153B2 true JP6078153B2 (ja) 2017-02-08

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ID=50149362

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Application Number Title Priority Date Filing Date
JP2015527749A Active JP6078153B2 (ja) 2012-08-24 2012-08-24 チアンジンアミド誘導体、並びにその医薬組成物及び使用

Country Status (7)

Country Link
US (1) US9359314B2 (https=)
EP (1) EP2889293B1 (https=)
JP (1) JP6078153B2 (https=)
KR (1) KR101899777B1 (https=)
CA (1) CA2882289C (https=)
ES (1) ES2629019T3 (https=)
WO (1) WO2014029102A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106316982B (zh) * 2015-06-30 2020-08-14 中国人民解放军军事医学科学院毒物药物研究所 噻嗪酰胺衍生物及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1173960C (zh) * 2001-12-06 2004-11-03 中国人民解放军军事医学科学院毒物药物研究所 取代六元氮杂环类化合物及其作为神经调节剂的用途
US9623000B2 (en) * 2008-07-31 2017-04-18 Dekel Pharmaceuticals Ltd Compositions and methods for treating inflammatory disorders
CN102675244B (zh) * 2011-03-16 2016-03-30 中国人民解放军军事医学科学院毒物药物研究所 噻嗪酰胺衍生物及其在制备神经退行性疾病防治药物的用途

Also Published As

Publication number Publication date
CA2882289C (en) 2019-09-17
US20150203460A1 (en) 2015-07-23
EP2889293B1 (en) 2017-04-26
KR20150046257A (ko) 2015-04-29
JP2015526447A (ja) 2015-09-10
HK1206019A1 (en) 2015-12-31
ES2629019T3 (es) 2017-08-07
KR101899777B1 (ko) 2018-09-20
CA2882289A1 (en) 2014-02-27
EP2889293A1 (en) 2015-07-01
WO2014029102A1 (zh) 2014-02-27
EP2889293A4 (en) 2015-12-30
US9359314B2 (en) 2016-06-07

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