JP6002675B2 - 細胞培養培地 - Google Patents

細胞培養培地 Download PDF

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Publication number
JP6002675B2
JP6002675B2 JP2013543905A JP2013543905A JP6002675B2 JP 6002675 B2 JP6002675 B2 JP 6002675B2 JP 2013543905 A JP2013543905 A JP 2013543905A JP 2013543905 A JP2013543905 A JP 2013543905A JP 6002675 B2 JP6002675 B2 JP 6002675B2
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laminin
cells
cell
cell culture
human
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JP2013545489A5 (https=
JP2013545489A (ja
Inventor
カルル トリュグヴァソン，
カルル トリュグヴァソン，
セルゲイ ロージン，
セルゲイ ロージン，
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ビオラミナ アーベー
ビオラミナ アーベー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/602—Sox-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/603—Oct-3/4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/605—Nanog
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/608—Lin28
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2013543905A 2010-12-17 2011-12-16 細胞培養培地 Active JP6002675B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201061424273P 2010-12-17 2010-12-17
US61/424,273 2010-12-17
US201161488353P 2011-05-20 2011-05-20
US61/488,353 2011-05-20
US201161533063P 2011-09-09 2011-09-09
US61/533,063 2011-09-09
US201161537940P 2011-09-22 2011-09-22
US61/537,940 2011-09-22
US201161565380P 2011-11-30 2011-11-30
US61/565,380 2011-11-30
US201161565849P 2011-12-01 2011-12-01
US61/565,849 2011-12-01
PCT/IB2011/003265 WO2012080844A1 (en) 2010-12-17 2011-12-16 Cell culture medium

Publications (3)

Publication Number Publication Date
JP2013545489A JP2013545489A (ja) 2013-12-26
JP2013545489A5 JP2013545489A5 (https=) 2015-02-05
JP6002675B2 true JP6002675B2 (ja) 2016-10-05

Family

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JP2013543905A Active JP6002675B2 (ja) 2010-12-17 2011-12-16 細胞培養培地
JP2013543904A Active JP5990531B2 (ja) 2010-12-17 2011-12-16 組換えラミニン−５２１

Family Applications After (1)

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JP2013543904A Active JP5990531B2 (ja) 2010-12-17 2011-12-16 組換えラミニン−５２１

Country Status (12)

Country Link
US (2) US10138292B2 (https=)
EP (2) EP2651973B1 (https=)
JP (2) JP6002675B2 (https=)
KR (3) KR101966033B1 (https=)
CN (2) CN103384680B (https=)
AU (1) AU2011342904B2 (https=)
BR (2) BR112013017629A2 (https=)
CA (2) CA2826252C (https=)
IL (2) IL226971B (https=)
MX (2) MX343462B (https=)
SG (3) SG10201510405PA (https=)
WO (2) WO2012080844A1 (https=)

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US10485829B2 (en) 2009-11-17 2019-11-26 Astellas Institute For Regenerative Medicine Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells
MX342995B (es) 2010-07-13 2016-10-21 Anthrogenesis Corp Métodos de generar células asesinas naturales.
CN103384680B (zh) 2010-12-17 2015-08-26 拜奥拉米那公司 细胞培养基
AU2012311233B2 (en) * 2011-09-22 2017-03-16 Sergey Rodin Cell culture substrate comprising a laminin and a cadherin
WO2013080051A2 (en) 2011-11-30 2013-06-06 Biolamina Ab Methods of enhancing genetic diagnosis
WO2013156855A1 (en) 2012-04-20 2013-10-24 Biolamina Ab Maintenance of differentiated cells with laminins
US20130330825A1 (en) * 2012-06-07 2013-12-12 City Of Hope Attachment substrates for directed differentiation of human embryonic stem cells in culture
DK2892996T3 (da) * 2012-09-07 2019-10-07 Biolamina Ab Stamcellebank
EP2925856B1 (en) 2012-12-03 2018-03-07 Biolamina AB Methods of producing rpe cells
AU2014215458A1 (en) 2013-02-05 2015-08-13 Anthrogenesis Corporation Natural killer cells from placenta
EP3546568A3 (en) 2013-07-02 2019-10-23 National University of Singapore Differentiation of pluripotent stem cells and cardiac progenitor cells into striated cardiomyocyte fibers using laminins ln-511, ln-521 and ln-221
EP3064572B1 (en) * 2013-11-01 2020-02-12 BBHC Co. Ltd. Method for producing induced pluripotent stem cell from mesenchymal stem cell and induced pluripotent stem cell produced by the method
BR112016011096A2 (pt) 2013-11-27 2017-09-19 Kyoto Prefectural Public Univ Corp Aplicação de laminina à cultura de célula endotelial da córnea
EP3213761B1 (en) * 2014-10-31 2021-05-19 Kyoto Prefectural Public University Corporation Novel treatment of retina using laminin
CN121891508A (zh) * 2014-10-31 2026-04-21 京都府公立大学法人 使用层粘连蛋白的新的角膜的治疗
ES2703167T5 (es) 2015-02-20 2022-09-30 Inst Nat Sante Rech Med Uso de una laminina para diferenciar células pluripotentes en células de linaje hepatocitario
WO2017034459A1 (en) * 2015-08-23 2017-03-02 Diamyd Medical Ab New use
WO2017072580A1 (en) * 2015-10-30 2017-05-04 Biolamina Ab Methods for producing hepatocytes
WO2017082026A1 (ja) * 2015-11-10 2017-05-18 日機装株式会社 細胞支持複合体および細胞支持複合体の製造方法
CN116121189A (zh) 2016-03-30 2023-05-16 阿斯特利亚斯生物治疗股份公司 少突胶质细胞祖细胞组合物
US20190211305A1 (en) * 2016-08-25 2019-07-11 Kyoto University Method for Culturing Pluripotent Stem Cells on Specific Laminin
SG11201903428XA (en) 2016-11-16 2019-05-30 Cynata Therapeutics Ltd Pluripotent stem cell assay
CN106591295B (zh) * 2016-12-31 2019-10-25 贵州北科生物科技有限公司 一种多功能干细胞培养方法及所用培养基
WO2018203834A1 (en) 2017-05-05 2018-11-08 National University Of Singapore Methods for culturing human keratinocytes
IL281628B2 (en) 2018-09-19 2025-06-01 Lineage Cell Therapeutics Inc Methods for differentiating pluripotent stem cells in dynamic suspension culture
WO2020154533A1 (en) 2019-01-23 2020-07-30 Asterias Biotherapeutics, Inc. Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells
CN111617105A (zh) * 2019-04-03 2020-09-04 成熙(上海)生物科技有限公司 一种脂肪干细胞多细胞活性因子冻干粉的制备方法
CN111621473A (zh) * 2019-04-03 2020-09-04 成熙(上海)生物科技有限公司 一种新型人源脂肪干细胞制剂的制备方法
WO2021233116A1 (zh) * 2020-05-21 2021-11-25 北京大学 多能干细胞的成分明确、无异源的培养系统
CN111569048B (zh) * 2020-05-22 2023-04-18 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 LamG5肽在制备修复睾丸中支持细胞损伤的药物中的应用
WO2025067551A1 (zh) * 2024-05-16 2025-04-03 北京百普赛斯生物科技股份有限公司 活性增强的改造型Laminin 521蛋白及应用

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CN103384680B (zh) 2010-12-17 2015-08-26 拜奥拉米那公司 细胞培养基

Also Published As

Publication number Publication date
KR101921350B1 (ko) 2018-11-22
MX343462B (es) 2016-11-07
MX345861B (es) 2017-02-20
SG10201510405PA (en) 2016-01-28
US20120156254A1 (en) 2012-06-21
CA2828794A1 (en) 2012-06-21
SG191216A1 (en) 2013-07-31
KR20190018024A (ko) 2019-02-20
CA2826252C (en) 2018-12-04
JP5990531B2 (ja) 2016-09-14
WO2012080844A1 (en) 2012-06-21
JP2014501101A (ja) 2014-01-20
BR112013017632A2 (pt) 2016-10-11
CA2826252A1 (en) 2012-06-21
CN103384679B (zh) 2015-08-26
AU2011342904B2 (en) 2016-05-12
WO2012080842A1 (en) 2012-06-21
KR20140016881A (ko) 2014-02-10
EP2651973B1 (en) 2016-08-31
CN103384679A (zh) 2013-11-06
SG191215A1 (en) 2013-07-31
MX2013006958A (es) 2013-12-16
BR112013017629A2 (pt) 2017-04-18
US10138292B2 (en) 2018-11-27
US20120156782A1 (en) 2012-06-21
CN103384680B (zh) 2015-08-26
US8415156B2 (en) 2013-04-09
EP2651974A1 (en) 2013-10-23
EP2651973A1 (en) 2013-10-23
JP2013545489A (ja) 2013-12-26
KR20140012047A (ko) 2014-01-29
EP2651974B1 (en) 2015-09-16
MX2013006959A (es) 2013-12-06
IL226971B (en) 2018-04-30
IL270186B (en) 2020-08-31
KR101966033B1 (ko) 2019-04-04
CA2828794C (en) 2021-07-13
CN103384680A (zh) 2013-11-06

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