JP5763342B2 - Adhesive patch for measuring acoustic signals - Google Patents

Adhesive patch for measuring acoustic signals Download PDF

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Publication number
JP5763342B2
JP5763342B2 JP2010538343A JP2010538343A JP5763342B2 JP 5763342 B2 JP5763342 B2 JP 5763342B2 JP 2010538343 A JP2010538343 A JP 2010538343A JP 2010538343 A JP2010538343 A JP 2010538343A JP 5763342 B2 JP5763342 B2 JP 5763342B2
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Prior art keywords
adhesive
member
means
adhesive patch
surface
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JP2011505997A (en
Inventor
ボー ボイェ クリステンセン,クラウス
ボー ボイェ クリステンセン,クラウス
ロン,ウェイミン
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アカリクス アクティーゼルスカブ
アカリクス アクティーゼルスカブ
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Priority to DKPA200701831 priority Critical
Priority to DKPA200701831 priority
Application filed by アカリクス アクティーゼルスカブ, アカリクス アクティーゼルスカブ filed Critical アカリクス アクティーゼルスカブ
Priority to PCT/DK2008/050310 priority patent/WO2009080040A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B7/00Instruments for auscultation
    • A61B7/02Stethoscopes
    • A61B7/04Electric stethoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683Means for maintaining contact with the body
    • A61B5/6832Means for maintaining contact with the body using adhesives
    • A61B5/6833Adhesive patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B7/00Instruments for auscultation
    • A61B7/006Detecting skeletal, cartilage or muscle noise
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0204Acoustic sensors

Description

  The present invention relates to an adhesive patch capable of detecting and recording an acoustic signal from a body.

  A device used for simple diagnosis widely used by doctors is a stethoscope, which is used to listen to changes in the function of the body through the skin of a human or animal. This stethoscope has been helping doctors to diagnose various diseases for hundreds of years. The problem with using a stethoscope is that the sound collected by the stethoscope is not properly amplified and reaches the doctor's ear through a flexible or rigid tubular material. This means that very small sounds in the body cannot be identified in real time with a stethoscope.

  One way to solve this problem is the invention of an electronic digital stethoscope that amplifies the level of sound from the body and processes it into a sound that is optimal for the doctor to listen to. It can be done. Older digital stethoscopes and conventional stethoscopes have the same drawback, which requires the doctor to listen in real time to the sound picked up by the stethoscope and make decisions based on that sound. That is what you have to do. However, modern digital stethoscopes can store a few seconds of recorded sound, and doctors can hear the sound stored in the digital stethoscope again.

  In Patent Document 1, this problem is sought to be solved by one or more wireless nodes forming a wireless network. The network communicates with a computer server type base station, and the node transmits patient data to the base station. It is designed to detect heart attacks or strokes.

  In the above-described apparatus, it is described that wireless nodes having various functions are collected, and one wireless node is an electronic stethoscope, and a heart sound using sound recorded from a patient's wrist is transmitted from the wireless node. Sent to the base station. Collecting wireless nodes needs to be continuously communicated to the base station. The disadvantage of this health care system is that the wireless node must communicate signals to the base station for analysis. This means that the user or doctor needs to communicate with the base station to obtain or access information about the patient's recorded data. Furthermore, since wireless communication is continuously performed with the base station, the amount of power used increases. This is because, in addition to sending recorded patient data, the collected nodes must be continuously checked and must receive confirmation.

  Coronary artery disease (CAD) is a threat to public health in Western societies, where smoking, increased stress, lack of exercise, obesity, etc. lead to coronary artery occlusion and direct and indirect coronary artery disease It has been reported to be a risk. In recent years, current methods for CAD diagnosis have become expensive and require complex instruments such as electrocardiograms, nuclear medicine examinations, angiography, CAT, MRI, etc. It takes a lot of time in the laboratory.

  Since these methods are expensive to perform, these methods are rarely used for screening, and CAD diagnosis for those showing signs of CAD such as chest pain is a problem. come.

US Patent Publication No. 2007/0276270

  Accordingly, there is a need for an improved method of monitoring CAD indications that utilizes acoustic signals from the human or animal body and the acoustic signals are selectively and / or continuously recorded and / or transmitted to external devices. is there. Selective transmission means that a normal signal is transmitted when an abnormal signal interrupts transmission.

  An object of the present invention is to provide an adhesive patch that can continuously measure an acoustic signal from a human body.

  Another object of the present invention is to provide an adhesive patch that alerts the user when the measured acoustic signal changes from a predetermined normal acoustic signal.

  It is a further object of the present invention to provide an adhesive patch that processes an acoustic signal in a predetermined manner, compares the processed signal with a standard value, and stores the acoustic signal for transmission to an external device. .

  Yet another object of the present invention is to provide an adhesive patch suitable for detecting early signs of coronary artery disease.

  The present invention is an adhesive patch for measuring an acoustic signal from a human body or an animal body, recording a skin contact surface and an acoustic signal, and converting the acoustic signal into a first electrical output signal. Converting means for transmitting, an adhesive element for attaching the converting means to the skin contact surface, transmitting means for transmitting the first electrical output signal to a surrounding device, the converting means and the skin contact surface Means for controlling the pressure between.

  The adhesive patch is provided with an adhesive layer on the skin contact surface, which ensures that the adhesive patch is attached in place after being placed on the user's skin surface. If the test results indicate that the conversion means is held in place with an analog or digital stethoscope by a user or expert and an acoustic signal is recorded, the conversion means is mechanical noise. The mechanical noise is caused by slight vibrations generated from the hand or human limb holding the conversion means in place. Some people have very stable hands, but it is impossible to remove all vibrations. This is because skeletal muscles are stimulated by periodic neural signals that cause very small vibrations in the muscles as each muscle fiber contracts.

  Vibration caused by the hand if the converting means is held in place using arms and / or hands to record the acoustic signal from the body, and the converting means is sensitive and can record weak signals Is a significant noise factor. This type of noise can be reduced by using embodiments of the present invention. In that embodiment, the converting means is attached to the skin surface using an adhesive patch so that it is not affected by vibrations in the hands of the specialist.

  It should be understood that the term “sound” is generally sent from the target site, such as the coronary artery, through the air and / or the human or animal body to the human body or transducing means. It is interpreted as a change in pressure. Mechanical noise caused by slight vibrations generated by the hand cannot be heard by the human ear without being processed, for example, by amplification and / or frequency modulation.

  Another advantage of attaching the transducing means to the skin surface is that the user can wear the adhesive patch for a long time and record the acoustic signal for a long time, depending on the need for diagnosis. .

  The recorded acoustic signal is converted into a first electrical output signal and transmitted directly to an external device by wireless or wired transmission means. It should be noted that the external device is a self-supporting unit independent of the adhesive patch, such as a personal computer (PC), mobile phone or PDA (personal digital assistant )). In the external device, the acoustic signal is further processed or not processed after an expert evaluates the content of the acoustic signal by listening with a loudspeaker, headphones or an electrical signal converter.

  The acoustic signal is recorded by positioning the transducer means or microphone in direct contact with the user's skin surface or by placing an acoustic transmission layer between the transducer means and the skin surface, in which case the acoustic transmission layer is It plays the role of sound transmission means. It has been discovered that any pressure change between the transducing means and the skin surface affects or reduces the transmission of sound between the skin surface and the transducing means. . Sound conduction, transmission and / or contact between the transducing means and the skin surface is achieved by keeping the pressure between the transducing means and the skin surface as stable as possible, ie changing the pressure when using an adhesive patch. It will be optimal by not letting it be, or by making the mounting pressure greater than any pressure fluctuation.

  This is accomplished by providing an elastic material that supports the surface of the converting means opposite the skin surface and that holds the converting means at a constant pressure against the skin surface, if the converting means to the skin. Alternatively, if the force acting on the conversion means from the skin surface changes, the elastic material absorbs at least a majority of the force and maintains the pressure between the skin surface and the conversion means.

  Another means for controlling the pressure between the conversion means and the skin surface is to provide a compression member on the skin contact surface. The compression member has one or more protrusions protruding from the skin contact surface. The protrusion is circular, oval, or an appropriate closed line shape, and the conversion means is disposed inside the closed line shape. Alternatively, the protrusions may be appropriately positioned protrusions located near and / or around the conversion means.

  When the skin contact surface of the adhesive patch is attached to the skin, the protrusion exerts a large pressure on the part of the skin in contact with the protrusion and the area defined by the protrusion. This means that when the skin contact surface of the adhesive patch is kept in contact with the adhesive patch, the skin surface inside the area defined by the protrusions is exposed to high tensile forces. ing. Even if the user moves or changes his / her posture, the compressive member maintains the skin pulling force inside the area defined by the protrusions, so that the pulling force on the skin surface does not change greatly. An acoustic medium can be applied to increase the tensile force of the skin surface within the skin contact surface defined by the area radially inward from the protrusion.

  By placing the conversion means on the skin surface inside the area defined by the protrusions so that the conversion means maintains a relative position in all directions with respect to the protrusions, the pressure of the conversion means when using the adhesive patch And the tension of the skin surface is controlled and maintained, so that the pressure between the conversion means and the skin surface is effectively controlled.

  Another way to control the pressure between the conversion means and the skin surface is to provide the conversion means inside a pressure cavity located in the adhesive patch. The skin contact surface of the adhesive patch acts as a gas and / or liquid impervious barrier between the adhesive patch and the skin surface. The pressure cavity has an outer wall that serves as an impervious barrier for gases and / or liquids to the atmosphere, and the barrier encloses gas or liquid that enters or enters the pressure cavity. I guarantee that. The adhesive patch may comprise a one-way valve and / or a two-way valve that introduces or pressures gas and / or liquid into the pressure cavity in order to control the pressure inside the pressure cavity. Used to release from the cavity. The conversion means may be placed in the pressure cavity in direct or indirect contact with the user's skin surface, and the pressure inside the pressure cavity is converted by either movement or change of the user's posture. The pressure between the means and the skin surface is not changed. In one embodiment of the invention, the adhesive patch may further comprise processing means for processing the first electrical output signal and converting it into a second electrical output signal. For this purpose, the adhesive patch has a processing means, which is a microprocessor, a microcontroller, an A / D converter, a digital signal processor and / or the necessary electrical circuitry, inside the adhesive patch. The acoustic signal is partially processed into a second electrical output signal.

  In the context of the present invention, the term “acoustic signal is partially processed” means that the acoustic signal is filtered, analog to digital conversion, digital or analog amplification, differential amplification, voltage amplification and similar signal processing. This means processing using analog or digital processing.

  In an embodiment of the invention, the adhesive patch further comprises analysis means for processing the first electrical output signal or the second electrical output signal and converting it into a third electrical output signal. . This means that the recorded acoustic signal is completely processed inside the adhesive patch.

  “Completely processing the recorded acoustic signal” means that the recorded signal is completely within the adhesive patch so that all signal processing that requires providing an indication of the abnormal signal is performed. It means that it has been processed. The signal processing steps are the same as described above. More fully processed signals have been processed into numerical values or mathematical formulas, which are compared to standard values or incorporated into a mathematical model, and the processing means can include some outliers in the recorded signal. If there is, you can display it.

  In one embodiment of the invention, the processing means determines whether the recorded signal deviates from a predetermined standard value. If the adhesive patch uses a standard value for comparison purposes, the standard value is selected based on the body acoustic signal to be monitored and the disease to be monitored. This is because the cardiac acoustic signal and the respiratory acoustic signal are not suitable for comparison.

  In one embodiment of the invention, the adhesive patch further comprises storage means for storing at least one of the first electrical output signal or the second electrical output signal or the third electrical output signal. Yes. This means that the expert can review some or all of the recorded signal after the user has installed the adhesive patch for monitoring purposes for a period of time. can do. Furthermore, the user does not need to go to the hospital when trying to perform monitoring. The user only needs to attach one or more adhesive patches, and then in normal life, the adhesive patch records an acoustic signal from the body.

  In one embodiment of the invention, the conversion means includes at least one microphone, which is used to record an acoustic signal from the body. The microphone generates a first electrical output signal that is stored inside the adhesive patch, transmitted to an external device, and processed and / or analyzed within the adhesive patch. In another embodiment of the invention, the conversion means may comprise at least two microphones, the first microphone is used for recording the acoustic signal from the body, and the second microphone is at least the surrounding microphone. Used to record a noise signal. By recording the acoustic signal simultaneously using two microphones, the noise signal obtained from the second microphone is used to remove the ambient noise recorded by the first microphone, which means that the noise The level is reduced and the remaining acoustic signal is the main acoustic signal from the body of interest in the diagnosis.

  A number of different types of microphones may be used to record acoustic signals from the body, and in one embodiment at least one microphone is a silicon microphone and in another embodiment at least one The microphone may be a pressure-sensitive contact microphone. In alternative embodiments of the present invention, the adhesive patch includes one or more microphones, and the microphones may be of various types. This has the following advantages: one type of microphone is suitable for recording noise, and the other type of microphone is suitable for recording acoustic signals from the body. It will be apparent to those skilled in the art that any type of microphone suitable for recording noise or acoustic signals from the body, etc. may be used in the adhesive patch based on the teachings of the present invention. .

  In order to improve the recording quality of the acoustic signal from the body, the adhesive patch may further include a sound collecting device. The sound collector is used to collect sound signals from a skin surface wider than the sound collection area of the conversion means. The sound collector focuses on acoustic signals that are directed to one or more sound collection areas. Specifically, a wide end collects an acoustic signal and has a funnel shape that collects the acoustic signal at a narrow end. By adding a sound collecting device, the converting means can target more acoustic signals than when using the converting means directly. This increases the sensitivity of the conversion means and allows the adhesive patch to acquire a weaker signal than when the sound collecting device is not used.

  In one embodiment of the present invention, the sound collecting device includes a bell-shaped section, and the converting means is disposed at the center of the section. The bell-shaped compartment allows the collected sound waves to be bounced off the wall and reflected towards the conversion means.

  In another embodiment, when the sound collector includes a diaphragm, the diaphragm vibrates when exposed to sound waves or vibrations based on a pressure differential acting on a skin surface area in communication with the diaphragm. Since the physical dimensions of the diaphragm affect the responsiveness of the diaphragm, the diaphragm acts as a filter.

  The adhesive patch includes a sound absorbing layer in order to reduce ambient noise that affects the converting means for recording or monitoring the acoustic signal from the body. The sound absorbing layer is used to block the conversion means from the outside and reduce noise from the surroundings.

  In one embodiment of the present invention, the sound absorbing layer comprises a high density material, such as a hydrocolloid material, and the hydrocolloid material may be an adhesive patch layer or a portion incorporated into the adhesive patch. Good. The sound insulation property of the hydrocolloid material depends on its thickness and its chemical composition. The thicker the material, the better the sound insulation property, and the material containing high-density particles attenuates noise and the sound insulation property is excellent. The hydrocolloid material is permeable to water vapor, and any water vapor introduced from the skin surface to the adhesive patch leaks from the adhesive patch through the hydrocolloid layer. The water vapor permeability of the hydrocolloid material reduces and protects the risk of electrical circuit water vapor damage within the adhesive patch.

  In order to facilitate acoustic transmission between the conversion means and the skin surface, the adhesive patch is provided with an acoustic transmission layer. The acoustic transmission layer improves the acoustic transmission characteristics between the transducing means and the skin surface. This is because the acoustic impedance between layers is reduced. This is because the acoustic transmission layer maintains the velocity of the sound wave received by reducing the acoustic impedance. This means that the sound wave traverses between the skin surface and the transducing means because the sound speed of the sound wave inside the acoustic transmission layer is maintained at the sound speed of the body by imitating the acoustic impedance of the skin layer. doing. Direct contact between the conversion means and the skin surface may reduce the acoustic properties of the acquired signal. This is because as the sound traverses from the skin surface toward the transducing means, an increase in acoustic impedance filters out a portion of the sound.

  In one embodiment of the invention, the acoustic transmission layer is made of an acoustic transmission gel. The speed of sound in the gel is the same as that of the skin layer. This means that sound is transmitted from the skin layer to the conversion means via the acoustic transmission gel without deterioration of sound quality due to the acoustic impedance described above.

  In one embodiment of the invention, the acoustic transmission layer is made of an acoustic transmission material provided as a coating covering a portion of the outer surface of the conversion means. The acoustic transmission material is a solid layer covering a part or the whole of the outer surface of the conversion means. Advantageously, the acoustic transmission material covers the outer surface of a suitable conversion means for obtaining an acoustic signal from the body.

  The acoustic transmission material may cover the entire surface of the transducer means, and the acoustic transmission material improves the acoustic transmission characteristics between the transducer means, the skin surface and the acoustic transmission material. In addition, the acoustic transmission material is also used to protect the transducer means from harmful contaminants that reduce the lifetime of the transducer means and degrade the performance of the transducer means for recording acoustic signals from the body, The pollutants are substances that are considered harmful, moisture, and pollutants.

  In one embodiment of the invention, the adhesive patch further comprises visual means for displaying the position of the adhesive patch by anatomical landmarks in the human or animal body. Visible means are used to facilitate the positioning of the adhesive patch with a predetermined anatomical landmark, the anatomical landmark depending on which acoustic measurement is performed. This means that the physical positioning of the adhesive patch facilitates certain types of acoustic measurements. This is important when the adhesive patch has one or more, eg 1D, 2D or 3D array conversion means for recording acoustic signals from the body. With respect to the output of the acoustic signal, which depends on the attachment of the adhesive patch, the exact position and spatial arrangement of the array is important.

  The adhesive patch may be used to measure respiratory signals, digestive signals, visceral signals, joint signals, urine signals and other signals from the body.

  In the present invention, an adhesive patch kit including an adhesive member and a conversion member is also disclosed. The adhesive member can be disposable after use, and the adhesive member can always be used with an optimum adhesive performance. The conversion member comprises an electrical circuit and conversion means necessary for recording an acoustic signal according to the invention. The individual parts of the conversion member, such as the conversion means, transmission means and / or processing means, are expensive compared to the adhesive member, and reducing the overall cost of diagnosis by using it many times. Is possible. The conversion member is attached to the adhesive member by provisional connection means, such as a hook-and-loop connection means, an adhesive means or an adhesive member and / or a mechanical connection means between the conversion members. Is. When the adhesive member and the conversion member are attached to each other, the two members form the adhesive patch in the present invention.

  The adhesive member may be a disinfected or non-sterilized adhesive member, and has a first connection means for temporarily connecting to a second connection means provided on the conversion member. Thus, the kit can be used such that the adhesive member is attached to the user's skin surface, and the conversion member is connected by connecting the adhesive member and the conversion member prior to attaching the adhesive patch to the user's skin surface. Subsequently, it is connected to the adhesive member. After the adhesive member kit is used to measure the acoustic signal from the body, the adhesive member and the conversion member are removed from the skin surface and each becomes a single member. The adhesive member is discarded, while the conversion member is prepared by a specialist for the next user by cleaning or disinfecting or reconditioning.

  The use of a disposable adhesive member ensures that the adhesive performance of the adhesive surface is optimal for attachment to the user's skin surface. It should also be understood that the adhesive surface is reusable so that the adhesive surface has the required adhesive performance until the last use of the kit adhesive member. Can be adjusted.

  The present invention further discloses a method for detecting an acoustic signal from a human body using an adhesive patch comprising conversion means, processing means and transmission means. The adhesive member is attached to the user's skin surface, and the conversion means is in direct or indirect contact with the skin surface. The converting means converts the recorded acoustic signal into an analog electrical signal, which is converted to a digital form using an A / D converter. The analog or digital signal is filtered using a bandpass filter having an upper and lower limit of a predetermined frequency to reduce the size. The upper and lower limits of the predetermined frequency are selected based on which acoustic signal of the body is measured.

  In one embodiment of the present invention, the converting means has two microphones, the first microphone records the acoustic signal from the body, the second microphone records the noise, and the two signals are the difference. Sent to the dynamic amplifier. The differential amplifier compares the input signals and reduces the value of the first microphone signal by the value of the synchronized signal of the second microphone. This means that the basic acoustic signal from the body is evident in the output signal of the differential amplifier.

  In one embodiment of the present invention, the output signal is transmitted to an external device using transmission means, and further signal processing is performed. In another embodiment, the output signal is sent to processing means and one or more signal processings are performed on the signal. The method is selected according to the type of acoustic signal from the body and may be selected from time-frequency analysis, statistical analysis and other well-known signal processing. The processing means may be supplemented by the analysis means, the processed signal or their mathematical representation may be compared with a standard value, and variations from the standard value can be detected by the analysis means. Yes.

  The acoustic signal acquired using the converting means is stored in a memory bank such as a flash memory or transmitted to an external device. Temporary storage or transmission is performed by a technician or expert. Further, a transmission means is used to program the adhesive patch, and gives instructions for each measurement to the adhesive patch.

  The present invention will be described in detail below with reference to the drawings.

FIG. 1 is an exploded view of an adhesive patch for detecting an acoustic signal from a main body according to the present invention. FIG. 2 is a cross-sectional view of the adhesive patch as viewed from the direction of arrows II-II in FIG. FIG. 3 is a cross-sectional view of the adhesive patch, and the adhesive patch includes a conversion member independent of the adhesive member. FIG. 4a is a cross-sectional view of an adhesive patch with a compression member. FIG. 4b is a cross-sectional view of an adhesive patch with a compression member. FIG. 5 is a cross-sectional view of an adhesive patch according to the present invention attached to a user's skin surface.

  FIG. 1 is an exploded view of an adhesive patch 1 for detecting an acoustic signal from a main body according to the present invention. The adhesive patch 1 is provided with a protective layer 2, which may appear as an envelope layer. The protective layer 2 includes a protruding portion 3, the protruding portion 3 is disposed substantially at the central portion of the protective layer, and protrudes away from the distal end of the protective layer 2 in the axial direction. The protective layer 2 comprises an adhesive layer 4, which ensures that the adhesive patch 1 can adhere to the skin surface of the object to be monitored. The adhesive layer 4 extends from the distal end of the protective layer and extends radially inward toward the central portion of the protective layer 2. In this embodiment, the adhesive layer 4 extends from the distal end, and extends radially inward toward the portion where the protruding portion 3 begins.

  The microphone 5 is provided on the inner surface of the protruding portion 3, that is, the surface adjacent to the adhesive layer 4. In this embodiment, the microphone 5 is in direct contact with the skin surface of the object, and when the adhesive patch 1 is attached to the skin surface, the protective layer does not separate the microphone and the skin surface. . This can be understood from the fact that the adhesive layer has an opening in the central portion that is the same size as the protruding portion 3. Furthermore, a pad 6 or a block of elastic material is arranged on the inner surface of the protruding part 3 between the protective layer 2 and the microphone 5 and provides support for the microphone 5. The elastic pad 6 ensures that the microphone 5 is pressed against the skin surface when the adhesive patch is attached to the skin surface of the user. The selection of the elastic material of the elastic pad 6 can be changed so that the contact between the skin surface and the microphone is at an optimum pressure under different circumstances.

  The microphone 5 is in electrical communication with the control unit 9 through a lead wire 7, and the lead wire 7 is taken out to the outer surface of the protective layer 2 through a small opening 8 in the protective layer 2. The lead wire 7 is connected to the control unit 9 at the assembly stage, and can communicate with the control unit 9. The opening 8 is large enough to allow the lead wire to pass through, but has a snug fit so that noise does not pass through the hole and prevent recording by the microphone 5.

  In one embodiment, the control unit 9 may be permanently connected to the protective layer 2, and in another embodiment the control unit 9 is removed if the protective layer 2 is discarded. The control unit 9 may be temporarily connected to the outer surface of the protective layer 2 so that it can. In this embodiment of the present invention, a second microphone 10 is attached to the outer surface of the protective layer 2, and the second microphone 10 is used to record noise from the surroundings. The second microphone 10 can perform electrical communication with the control unit via the lead wire 11.

  In another embodiment of the adhesive patch, the protective layer 2 may be an adhesive material, which means that no special adhesive layer 4 is required to attach the adhesive patch to the user's skin surface. I mean. In this case, the outer surface of the adhesive patch may include a protective film so that the outer surface of the adhesive patch 1 does not adhere.

  FIG. 2 is a cross-sectional view of the adhesive patch as viewed from the direction of arrows II-II in FIG. 1, in which various parts of the adhesive patch are assembled. In this assembled state, the first microphone 5 protrudes from the surface defined by the adhesive layer 4, and when the adhesive patch is adhered to the skin surface, the microphone is pushed into the skin surface and the elastic pad 6. The elastic pad 6 provides an optimum pressure between the first microphone 5 and the skin surface.

  In the present embodiment, the first microphone 5 is in electrical communication with the control unit 9, and the lead wire 7 passes through the opening 8 from the inner space 12 of the adhesive patch to the outer surface of the adhesive patch. .

  In the present invention, the control unit 9 has the electrical circuitry necessary to convert, process, transmit, store and analyze the electrical signals from the first microphone 5 and the second microphone 10. The electrical circuit for processing the electrical signal may be selected from the group of prior art filter components, A / D converters, microprocessors, wireless transmission modules, flash memory chips, USB controllers or similar electronic components. The control unit 9 may further comprise an on / off switch that is used to activate or deactivate the adhesive patch.

  The control unit 9 further comprises a power source for supplying current to the electrical circuit and electrical or electronic components of the adhesive patch, the power source being a disposable battery or a rechargeable battery, a power converter, etc. It is.

  FIG. 3 is a schematic view of one embodiment of an adhesive patch 30 according to the present invention, wherein the adhesive member 31 and the conversion member 32 are connected to each other via a first connection means 33 and a second connection means 34. It is detachably connected. Adhesive member 31 includes an adhesive surface 35 that provides a skin contact surface and a non-adhesive outer surface 36 that does not face skin contact surface 35. The adhesive member has an opening 37 through which the adhesive member 31 passes, and the opening 37 communicates from the outer surface 36 of the adhesive member 31 to the skin contact surface 35.

  The conversion member 32 includes a housing 38 having a cylindrical wall 39 and a rear wall 40 defining an internal cavity 41, the internal cavity 41 being a pressure treatment element (a pressure) of an elastic foam or similar material. management element) 42 and conversion means 43 in the form of a microphone or acoustic transducer. The conversion member 32 may be connected to the first connection means 33 surrounding the opening 37 in the shape of a connection ring, so that the ring 33 cannot be removed from the outer surface 36 of the adhesive member 31. It is attached. The free end of the housing 38 comprises a second connecting means 34 in the form of a first radial protrusion 44 adapted to engage the second protrusion, the second protrusion being connected. It is provided as a protrusion 45 or rim at the free end of the ring 33. Since the conversion member is attached to the adhesive member, the skin contact surface 46 of the conversion means 43 is substantially parallel to the skin contact surface of the adhesive member 31, which means that the adhesive patch 40 is attached to the user's skin surface. As such, the conversion member is meant to contact the skin surface. Based on the teachings of the present invention, modifications relating to the selection of dimensions, shapes and materials may be made.

FIG. 4 a is a schematic view of the adhesive member 31 having a compression member 47 on the skin contact surface 35 of the adhesive member 31. The compression member 47 is formed as an inclined surface portion 48 of the skin contact surface 35 and protrudes in a direction away from the adhesive member 31. Although the inclined surface portion 48 can be seen the thickness of the adhesive member 31 is increased, the thickness of the adhesive member thin no longer in a portion spaced radially from the opening, and thicker at the portion close to the opening 37 It has become.

  FIG. 4 b has a compression member 50 in the form of an annular protrusion 51 on the skin contact surface 35 of the adhesive member 31.

  FIG. 5 shows an adhesive patch 60 attached to the user's skin surface according to the present invention, the adhesive patch 60 having the compression member 62 illustrated in FIG. 4a, the compression member 62 being open. Surrounding the portion 63, the inclined surface 64 or protrusion shown in FIG. 4b stretches the skin surface 65 inside the user's opening 63 and / or increases the surface tension when the adhesive patch 60 is attached. As the adhesive patch 60 continues to be used, the tensile force of the skin surface 63 is maintained. In this embodiment, even if the skin surface 66 surrounding the adhesive patch 60 is stretched, deformed or moved, the surface tension of the skin surface 63 inside the opening 63 is maintained, Therefore, the pressure between the conversion member 67 and the skin surface 65 is controlled. In this embodiment, the acoustic transmission layer 68 is attached between the skin surface 64 and the conversion member 67.

  The acoustic transmission layer 68 extends over the entire opening 63 or a part thereof. Layer 68 has an adherent skin contact surface and an adhesive layer on the opposite surface. The layer 68 may be in the form of a gel or a gas such as air. Any suitable acoustic transmission material in the prior art may be used to facilitate acoustic transmission between the skin surface and the transducing member.

  In the embodiment in FIGS. 4 and 5, a two-part device is shown, wherein the conversion member is detachably connected to the adhesive member. In other embodiments, the same or similar compression member is provided, and the adhesive member is non-removably attached to the conversion member, as illustrated in FIG.

  Modifications to the shape, size, and structure of the compression members in FIGS. 4 and 5 may be made.

Claims (9)

  1. An adhesive patch for measuring acoustic signals from the human or animal body,
    An adhesive member (31) and a conversion member (32);
    The adhesive member (31) includes an adhesive surface (35) that provides a skin contact surface, and a non-adhesive outer surface (36) that does not face the skin contact surface. A through opening (37) leading from the outer surface (36) of the adhesive member (31) to the skin contact surface;
    The conversion member (32) includes a housing (38) having a cylindrical wall surface (39) and a rear wall surface ( 40 ) defining an internal cavity (41), and the internal cavity (41) is elastic. Containing pressure processing means (42) in the form of a foam or similar material and a converting means (43) for detecting the acoustic signal and converting the detected acoustic signal into a first electrical output signal; The conversion means (43) includes a skin contact surface (46), and the pressure treatment means (42) supports the side of the conversion means (43) opposite to the skin contact surface (46). , Disposed between the rear wall surface (40) and the converting means (43),
    The adhesive patch further comprises a transmission means for transmitting the electrical output signal to a surrounding device.
    When the conversion member is connected to the adhesive member, the skin contact surface (46) of the conversion means (43) disposed in the through opening (37) is the surface of the adhesive member (31). Being substantially parallel to the skin contact surface results in the conversion member coming into contact with the skin surface when the adhesive patch is attached to the user's skin surface, and the skin of the adhesive member. A compression member (47, 50) in the form of one or more protrusions (48, 51) projecting from the contact surface, arranged close to and / or surrounding the conversion means The compression member (47, 50) is provided on the skin contact surface of the adhesive member, and the adhesive member and the conversion member are mutually connected via the first connection means (33) and the second connection means (34). Releasably connectable And wherein a call, adhesive patch.
  2.   The compression member (47) is formed as a sloped surface portion (48) that provides an increase in the thickness of the adhesive member (31), the adhesive member being radially away from the through opening (37). The adhesive patch according to claim 1, wherein the patch is thin at a portion and the inclined surface portion (48) is thick at a portion close to the opening (37).
  3.   The adhesive patch according to claim 1, wherein the compression member (50) is in the form of an annular protrusion (51) in the skin contact surface (35) of the adhesive member (31).
  4.   The adhesive patch according to claim 1 or 2, wherein the compression member is formed to increase the surface tension of a user's skin.
  5.   The adhesive member comprises an acoustic transmission layer, and the acoustic transmission layer is made of an acoustic transmission material provided as a film covering at least a part of the outer surface of the conversion means. Adhesive patch.
  6.   The adhesive patch according to any one of claims 1 to 5, wherein the conversion means includes at least one microphone.
  7.   The adhesive patch according to claim 6, wherein the at least one microphone is a silicon microphone or a pressure-sensitive contact microphone.
  8.   The adhesive patch according to claim 1, further comprising processing means (9) for processing the first electrical output signal and converting the signal into at least a second electrical output signal.
  9.   The adhesive patch according to claim 1, wherein the adhesive member is a disposable part and the conversion member is a reusable part.
JP2010538343A 2007-12-20 2008-12-16 Adhesive patch for measuring acoustic signals Active JP5763342B2 (en)

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DKPA200701831 2007-12-20
PCT/DK2008/050310 WO2009080040A1 (en) 2007-12-20 2008-12-16 An adhesive patch for monitoring acoustic signals

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PL2230997T3 (en) 2014-07-31
DK2230997T3 (en) 2014-05-12
CN101951830A (en) 2011-01-19
BRPI0821411A2 (en) 2015-06-16
CA2709637C (en) 2016-10-04
ES2455040T3 (en) 2014-04-14
AU2008340865B2 (en) 2014-01-23
AU2008340865A1 (en) 2009-07-02
RU2484764C2 (en) 2013-06-20
CN101951830B (en) 2012-11-28
EP2230997B1 (en) 2014-03-05
CA2709637A1 (en) 2009-07-02
WO2009080040A1 (en) 2009-07-02
EP2230997A1 (en) 2010-09-29
US20110034831A1 (en) 2011-02-10
US8911383B2 (en) 2014-12-16
US20150099998A1 (en) 2015-04-09
JP2011505997A (en) 2011-03-03
US9566041B2 (en) 2017-02-14
RU2010130080A (en) 2012-01-27

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