JP5732058B2 - 眼科用水性注射可能組成物およびその使用方法 - Google Patents
眼科用水性注射可能組成物およびその使用方法 Download PDFInfo
- Publication number
- JP5732058B2 JP5732058B2 JP2012530970A JP2012530970A JP5732058B2 JP 5732058 B2 JP5732058 B2 JP 5732058B2 JP 2012530970 A JP2012530970 A JP 2012530970A JP 2012530970 A JP2012530970 A JP 2012530970A JP 5732058 B2 JP5732058 B2 JP 5732058B2
- Authority
- JP
- Japan
- Prior art keywords
- composition
- therapeutic agent
- highly viscous
- viscous mass
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 CC*(C)=CCCCCCN Chemical compound CC*(C)=CCCCCCN 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24491609P | 2009-09-23 | 2009-09-23 | |
US61/244,916 | 2009-09-23 | ||
PCT/US2010/049623 WO2011037908A1 (en) | 2009-09-23 | 2010-09-21 | Injectable aqueous ophthalmic composition and method of use therefor |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015082366A Division JP2015129194A (ja) | 2009-09-23 | 2015-04-14 | 眼科用水性注射可能組成物およびその使用方法 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2013505934A JP2013505934A (ja) | 2013-02-21 |
JP2013505934A5 JP2013505934A5 (pt) | 2013-10-10 |
JP5732058B2 true JP5732058B2 (ja) | 2015-06-10 |
Family
ID=43034434
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012530970A Expired - Fee Related JP5732058B2 (ja) | 2009-09-23 | 2010-09-21 | 眼科用水性注射可能組成物およびその使用方法 |
JP2015082366A Withdrawn JP2015129194A (ja) | 2009-09-23 | 2015-04-14 | 眼科用水性注射可能組成物およびその使用方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015082366A Withdrawn JP2015129194A (ja) | 2009-09-23 | 2015-04-14 | 眼科用水性注射可能組成物およびその使用方法 |
Country Status (15)
Country | Link |
---|---|
US (3) | US20110071091A1 (pt) |
EP (1) | EP2480205B1 (pt) |
JP (2) | JP5732058B2 (pt) |
KR (2) | KR20120069741A (pt) |
CN (1) | CN102695497B (pt) |
AR (1) | AR078293A1 (pt) |
AU (1) | AU2010298480B2 (pt) |
BR (1) | BR112012006642A2 (pt) |
CA (1) | CA2772795A1 (pt) |
ES (1) | ES2568462T3 (pt) |
MX (1) | MX2012003196A (pt) |
PL (1) | PL2480205T3 (pt) |
TW (1) | TWI492769B (pt) |
WO (1) | WO2011037908A1 (pt) |
ZA (1) | ZA201201438B (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2393768T3 (es) | 2005-05-26 | 2012-12-27 | Neuron Systems, Inc | Derivado de quinolina para el tratamiento de enfermedades retinianas |
TWI492769B (zh) | 2009-09-23 | 2015-07-21 | Alcon Res Ltd | 可注射的水性眼用組成物及其使用之方法 |
US9498035B2 (en) | 2012-12-21 | 2016-11-22 | Coopervision International Holding Company, Lp | Silicone hydrogel contact lenses for sustained release of beneficial polymers |
US20140178327A1 (en) | 2012-12-21 | 2014-06-26 | Coopervision International Holding Company, Lp | Antimicrobial Ophthalmic Devices |
CA2898631C (en) | 2013-01-23 | 2023-06-13 | Aldeyra Therapeutics, Inc. | Toxic aldehyde related diseases and treatment |
US20160279055A1 (en) * | 2013-07-22 | 2016-09-29 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof |
US20150164882A1 (en) | 2013-07-22 | 2015-06-18 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions for intraocular administration and methods for fabricating thereof |
US20170119885A1 (en) * | 2014-04-28 | 2017-05-04 | Hampton Technologies | Ophthalmic compositions and methods for treating eyes |
US20150366311A1 (en) | 2014-06-19 | 2015-12-24 | Coopervision International Holding Company, Lp | Protection of Contact Lenses from Microbial Contamination Caused by Handling |
EP3302061A4 (en) * | 2015-06-05 | 2019-02-27 | Kato Pharmaceuticals, Inc. | EXTENDED RELEASE COMPOSITIONS |
US10550085B2 (en) | 2015-08-21 | 2020-02-04 | Aldeyra Therapeutics, Inc. | Deuterated compounds and uses thereof |
ES2908479T3 (es) | 2015-08-26 | 2022-04-29 | Achillion Pharmaceuticals Inc | Compuestos para el tratamiento de trastornos inmunitarios e inflamatorios |
AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
WO2017196881A1 (en) | 2016-05-09 | 2017-11-16 | Aldeyra Therapeutics, Inc. | Combination treatment of ocular inflammatory disorders and diseases |
JP7057290B2 (ja) | 2016-06-27 | 2022-04-19 | アキリオン ファーマシューティカルズ,インコーポレーテッド | 医学的障害を治療するためのキナゾリン及びインドール化合物 |
IL303696A (en) | 2017-03-01 | 2023-08-01 | Achillion Pharmaceuticals Inc | Aryl, heteroaryl and heterocyclic pharmaceutical compounds for the treatment of medical disorders |
JP7311162B2 (ja) | 2017-10-10 | 2023-07-19 | アルデイラ セラピューティクス, インコーポレイテッド | 炎症性障害の処置 |
JP2021533154A (ja) | 2018-08-06 | 2021-12-02 | アルデイラ セラピューティクス, インコーポレイテッド | 多形化合物およびその使用 |
WO2020041301A1 (en) | 2018-08-20 | 2020-02-27 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
WO2020081723A1 (en) | 2018-10-16 | 2020-04-23 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
WO2020118045A1 (en) * | 2018-12-05 | 2020-06-11 | Aldeyra Therapeutics, Inc. | Injectable formulations |
JP2022530967A (ja) | 2019-05-02 | 2022-07-05 | アルデイラ セラピューティクス, インコーポレイテッド | 多形化合物およびその使用 |
WO2021231792A1 (en) | 2020-05-13 | 2021-11-18 | Aldeyra Therapeutics, Inc. | Pharmaceutical formulations and uses thereof |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0244178A3 (en) * | 1986-04-28 | 1989-02-08 | Iolab, Inc | Intraocular dosage compositions and method of use |
US7947295B2 (en) * | 2003-06-13 | 2011-05-24 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
KR101352666B1 (ko) | 2004-09-24 | 2014-02-14 | 허큘레스 인코포레이티드 | 피부관리 제품용 높은 ds 양이온성 폴리갈락토만난 |
KR20070104931A (ko) * | 2005-02-09 | 2007-10-29 | 마커사이트, 인코포레이티드 | 안구 치료용 제제 |
CN100433805C (zh) * | 2005-06-29 | 2008-11-12 | 上海广电(集团)有限公司中央研究院 | 一种数字电视接收机及其信号传递方法 |
AU2006302212B2 (en) * | 2005-10-08 | 2012-12-20 | Apellis Pharmaceuticals, Inc. | Compstatin and analogs thereof for eye disorders |
US8168584B2 (en) * | 2005-10-08 | 2012-05-01 | Potentia Pharmaceuticals, Inc. | Methods of treating age-related macular degeneration by compstatin and analogs thereof |
JP5528708B2 (ja) | 2006-02-09 | 2014-06-25 | 参天製薬株式会社 | 安定な製剤ならびにそれらを調製および使用する方法 |
MX2010003630A (es) * | 2007-10-02 | 2010-04-21 | Potentia Pharmaceuticals Inc | Administracion sostenida de analogos de compstatina desde geles. |
WO2010045506A2 (en) * | 2008-10-16 | 2010-04-22 | Kathleen Cogan Farinas | Sustained drug delivery system |
US8530189B2 (en) | 2008-10-16 | 2013-09-10 | Kathleen Cogan Farinas | Sustained drug delivery system |
TWI492769B (zh) | 2009-09-23 | 2015-07-21 | Alcon Res Ltd | 可注射的水性眼用組成物及其使用之方法 |
AU2011248129B2 (en) * | 2010-05-05 | 2014-10-09 | Alcon Inc. | Stabilized ophthalmic galactomannan formulations |
-
2010
- 2010-08-27 TW TW099128926A patent/TWI492769B/zh not_active IP Right Cessation
- 2010-09-20 AR ARP100103414A patent/AR078293A1/es unknown
- 2010-09-21 MX MX2012003196A patent/MX2012003196A/es active IP Right Grant
- 2010-09-21 AU AU2010298480A patent/AU2010298480B2/en not_active Ceased
- 2010-09-21 EP EP10757550.8A patent/EP2480205B1/en not_active Not-in-force
- 2010-09-21 PL PL10757550.8T patent/PL2480205T3/pl unknown
- 2010-09-21 JP JP2012530970A patent/JP5732058B2/ja not_active Expired - Fee Related
- 2010-09-21 KR KR1020127010271A patent/KR20120069741A/ko active Search and Examination
- 2010-09-21 CN CN201080042658.9A patent/CN102695497B/zh not_active Expired - Fee Related
- 2010-09-21 KR KR1020177001319A patent/KR20170008895A/ko not_active Application Discontinuation
- 2010-09-21 BR BR112012006642A patent/BR112012006642A2/pt not_active IP Right Cessation
- 2010-09-21 WO PCT/US2010/049623 patent/WO2011037908A1/en active Application Filing
- 2010-09-21 CA CA2772795A patent/CA2772795A1/en not_active Abandoned
- 2010-09-21 US US12/886,988 patent/US20110071091A1/en not_active Abandoned
- 2010-09-21 ES ES10757550.8T patent/ES2568462T3/es active Active
-
2012
- 2012-02-27 ZA ZA2012/01438A patent/ZA201201438B/en unknown
-
2013
- 2013-10-18 US US14/057,125 patent/US9446093B2/en not_active Expired - Fee Related
-
2015
- 2015-04-14 JP JP2015082366A patent/JP2015129194A/ja not_active Withdrawn
-
2016
- 2016-08-24 US US15/245,496 patent/US20160361254A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2480205B1 (en) | 2016-03-16 |
TW201111003A (en) | 2011-04-01 |
CN102695497B (zh) | 2016-01-06 |
AU2010298480A1 (en) | 2012-03-29 |
AU2010298480B2 (en) | 2014-08-07 |
JP2015129194A (ja) | 2015-07-16 |
MX2012003196A (es) | 2012-04-30 |
CN102695497A (zh) | 2012-09-26 |
JP2013505934A (ja) | 2013-02-21 |
ZA201201438B (en) | 2013-05-29 |
US9446093B2 (en) | 2016-09-20 |
ES2568462T3 (es) | 2016-04-29 |
US20140094419A1 (en) | 2014-04-03 |
PL2480205T3 (pl) | 2016-09-30 |
BR112012006642A2 (pt) | 2016-05-03 |
KR20170008895A (ko) | 2017-01-24 |
EP2480205A1 (en) | 2012-08-01 |
WO2011037908A1 (en) | 2011-03-31 |
US20110071091A1 (en) | 2011-03-24 |
TWI492769B (zh) | 2015-07-21 |
US20160361254A1 (en) | 2016-12-15 |
CA2772795A1 (en) | 2011-03-31 |
AR078293A1 (es) | 2011-10-26 |
KR20120069741A (ko) | 2012-06-28 |
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