JP5715241B2 - 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 - Google Patents

新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 Download PDF

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JP5715241B2
JP5715241B2 JP2013510364A JP2013510364A JP5715241B2 JP 5715241 B2 JP5715241 B2 JP 5715241B2 JP 2013510364 A JP2013510364 A JP 2013510364A JP 2013510364 A JP2013510364 A JP 2013510364A JP 5715241 B2 JP5715241 B2 JP 5715241B2
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compound
brd4
cell
certain embodiments
optionally substituted
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Japanese (ja)
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JP2013532130A5 (https=
JP2013532130A (ja
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ブラドナー，ジェームズ，エリオット
チー，チュン
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Dana Farber Cancer Institute Inc
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Dana Farber Cancer Institute Inc
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Priority claimed from PCT/US2011/036701 external-priority patent/WO2011143669A2/en
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2013510364A 2010-05-14 2011-05-16 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 Active JP5715241B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US33499110P 2010-05-14 2010-05-14
US61/334,991 2010-05-14
US37074510P 2010-08-04 2010-08-04
US61/370,745 2010-08-04
US37586310P 2010-08-22 2010-08-22
US61/375,863 2010-08-22
PCT/US2011/036701 WO2011143669A2 (en) 2010-05-14 2011-05-16 Compositions and methods for treating neoplasia, inflammatory disease and other disorders

Related Child Applications (1)

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JP2015049960A Division JP5937247B2 (ja) 2010-05-14 2015-03-12 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法

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JP2013532130A JP2013532130A (ja) 2013-08-15
JP2013532130A5 JP2013532130A5 (https=) 2014-11-06
JP5715241B2 true JP5715241B2 (ja) 2015-05-07

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JP2013510364A Active JP5715241B2 (ja) 2010-05-14 2011-05-16 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法
JP2015049960A Active JP5937247B2 (ja) 2010-05-14 2015-03-12 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法

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Families Citing this family (15)

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Publication number Priority date Publication date Assignee Title
JP3182721B2 (ja) 1997-08-06 2001-07-03 理兆 上田 自動車のペダル装置
PL2902030T3 (pl) 2010-05-14 2017-07-31 Dana-Farber Cancer Institute, Inc. Związki tienotriazolodiazepinowe do leczenia nowotworu
CN103119160B (zh) * 2010-05-14 2016-06-01 达那-法伯癌症研究所 用于调节代谢的组合物和方法
AU2013283378B2 (en) * 2012-06-25 2017-07-13 Oncoethix Gmbh Method of treating lymphoma using thienotriazolodiazepine compounds
JP2016529246A (ja) * 2013-08-06 2016-09-23 オンコエシックス ゲーエムベーハー Ｂｅｔブロモドメイン阻害剤を用いるびまん性大細胞型ｂ細胞性リンパ腫（ｄｌｂｃｌ）の治療方法
RU2016122654A (ru) 2013-11-08 2017-12-14 Дана-Фарбер Кэнсер Инститьют, Инк. Комбинированная терапия злокачественной опухоли с использованием ингибиторов бромодоменового и экстратерминального (вет) белка
JP2017506666A (ja) 2014-02-28 2017-03-09 テンシャ セラピューティクス，インコーポレイテッド 高インスリン血症に関連した症状の処置
US20180193350A1 (en) * 2015-06-26 2018-07-12 Tensha Therapeutics, Inc. Treatment of nut midline carcinoma
RU2018112953A (ru) 2015-09-11 2019-10-14 Дана-Фарбер Кэнсер Инститьют, Инк. Ацетамидтиенотриазолодиазепины и пути их применения
EP3347021A4 (en) * 2015-09-11 2019-07-24 Dana-Farber Cancer Institute, Inc. CYANOTHIENOTRIAZOLDIAZEPINE AND USES THEREOF
EP3355922A2 (en) * 2015-10-02 2018-08-08 Dana Farber Cancer Institute, Inc. Combination therapy of bromodomain inhibitors and checkpoint blockade
US11548899B2 (en) * 2016-02-15 2023-01-10 The Regents Of The University Of Michigan Fused 1,4-oxazepines and related analogs as BET bromodomain inhibitors
CA3041949A1 (en) * 2016-12-16 2018-06-21 F. Hoffmann-La Roche Ag Process for the manufacture of diazepine derivatives
CN109503618A (zh) * 2017-09-14 2019-03-22 成都海创药业有限公司 一种brd4抑制剂
AU2019284971A1 (en) * 2018-06-13 2020-12-03 Worg Pharmaceuticals (Zhejiang) Co., Ltd. Preparation of condensed triazepine derivatives and their use as BET inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2258053A1 (en) * 1996-06-12 1997-12-18 Yoshihisa Yamamoto Cytokine production inhibitors, triazepine compounds, and intermediates thereof
US7589167B2 (en) * 2000-02-22 2009-09-15 J. David Gladstone Institutes ZA loops of bromodomains
CA2515790C (en) * 2003-02-27 2012-11-27 Abbott Laboratories Heterocyclic kinase inhibitors
KR101600634B1 (ko) * 2007-12-28 2016-03-07 미쓰비시 타나베 파마 코퍼레이션 항암제
EP3050885B1 (en) * 2009-11-05 2017-10-18 GlaxoSmithKline LLC Benzodiazepine bromodomain inhibitor

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JP2015147777A (ja) 2015-08-20
JP5937247B2 (ja) 2016-06-22
JP2013532130A (ja) 2013-08-15

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