JP5688902B2 - 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス - Google Patents

莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス Download PDF

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JP5688902B2
JP5688902B2 JP2009554744A JP2009554744A JP5688902B2 JP 5688902 B2 JP5688902 B2 JP 5688902B2 JP 2009554744 A JP2009554744 A JP 2009554744A JP 2009554744 A JP2009554744 A JP 2009554744A JP 5688902 B2 JP5688902 B2 JP 5688902B2
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protein
capsular polysaccharide
producing
diafiltration
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JP2010521972A (ja
JP2010521972A5 (https=
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ヨンホイ ユアン，
ヨンホイ ユアン，
マーク ラッペン，
マーク ラッペン，
ウェイ−チーアン サン，
ウェイ−チーアン サン，
リン チュー，
リン チュー，
ジョン シンプソン，
ジョン シンプソン，
ジェームス パッチ，
ジェームス パッチ，
シャルボノー， パメラ フィンク
シャルボノー， パメラ フィンク
ジャスティン ケー． モーラン，
ジャスティン ケー． モーラン，
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ワイス・エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2009554744A 2007-03-23 2008-03-20 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス Active JP5688902B2 (ja)

Applications Claiming Priority (3)

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US89661607P 2007-03-23 2007-03-23
US60/896,616 2007-03-23
PCT/US2008/057688 WO2008118752A2 (en) 2007-03-23 2008-03-20 Shortened purification process for the production of capsular streptococcus pneumoniae polysaccharides

Related Child Applications (1)

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JP2015013167A Division JP2015143225A (ja) 2007-03-23 2015-01-27 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス

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JP2010521972A JP2010521972A (ja) 2010-07-01
JP2010521972A5 JP2010521972A5 (https=) 2011-05-06
JP5688902B2 true JP5688902B2 (ja) 2015-03-25

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JP2009554744A Active JP5688902B2 (ja) 2007-03-23 2008-03-20 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス
JP2015013167A Withdrawn JP2015143225A (ja) 2007-03-23 2015-01-27 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス
JP2017056848A Active JP6825950B2 (ja) 2007-03-23 2017-03-23 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス
JP2018208647A Withdrawn JP2019048844A (ja) 2007-03-23 2018-11-06 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス
JP2020014532A Active JP6872649B2 (ja) 2007-03-23 2020-01-31 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス

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JP2015013167A Withdrawn JP2015143225A (ja) 2007-03-23 2015-01-27 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス
JP2017056848A Active JP6825950B2 (ja) 2007-03-23 2017-03-23 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス
JP2018208647A Withdrawn JP2019048844A (ja) 2007-03-23 2018-11-06 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス
JP2020014532A Active JP6872649B2 (ja) 2007-03-23 2020-01-31 莢膜Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅ多糖の生産のための短縮された精製プロセス

Country Status (29)

Country Link
US (3) US8652480B2 (https=)
EP (3) EP2436700B8 (https=)
JP (5) JP5688902B2 (https=)
KR (2) KR20150021127A (https=)
CN (1) CN101663327B (https=)
AU (1) AU2008231041B2 (https=)
BR (1) BRPI0809212B8 (https=)
CA (1) CA2681570C (https=)
CL (2) CL2008000831A1 (https=)
CO (1) CO6251324A2 (https=)
CR (1) CR11041A (https=)
DK (3) DK2129693T3 (https=)
EC (1) ECSP099652A (https=)
ES (3) ES2677353T3 (https=)
GT (1) GT200900249A (https=)
HN (1) HN2009001965A (https=)
HU (3) HUE031567T2 (https=)
IL (1) IL201106A (https=)
MX (1) MX2009010221A (https=)
MY (1) MY150927A (https=)
NI (1) NI200900172A (https=)
NZ (1) NZ580134A (https=)
PL (3) PL3406635T3 (https=)
PT (3) PT2129693T (https=)
RU (1) RU2516340C2 (https=)
SI (3) SI2436700T1 (https=)
UA (1) UA99278C2 (https=)
WO (1) WO2008118752A2 (https=)
ZA (1) ZA200906625B (https=)

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