JP5604248B2 - Endoscopic image display device - Google Patents

Endoscopic image display device Download PDF

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JP5604248B2
JP5604248B2 JP2010217961A JP2010217961A JP5604248B2 JP 5604248 B2 JP5604248 B2 JP 5604248B2 JP 2010217961 A JP2010217961 A JP 2010217961A JP 2010217961 A JP2010217961 A JP 2010217961A JP 5604248 B2 JP5604248 B2 JP 5604248B2
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light
intensity
display device
captured image
endoscope
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JP2012070935A (en
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弥 佐々木
悟朗 三浦
邦政 清水
充史 三沢
保宏 浅井
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富士フイルム株式会社
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002Operational features of endoscopes
    • A61B1/00004Operational features of endoscopes characterised by electronic signal processing
    • A61B1/00009Operational features of endoscopes characterised by electronic signal processing of image signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002Operational features of endoscopes
    • A61B1/00043Operational features of endoscopes provided with signal output arrangements
    • A61B1/00045Display arrangement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/063Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements for monochromatic illumination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0646Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements with illumination filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0653Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements with wavelength conversion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002Operational features of endoscopes
    • A61B1/00011Operational features of endoscopes characterised by data transmission
    • A61B1/00018Operational features of endoscopes characterised by data transmission using electrical cables
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/05Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion

Description

  The present invention relates to an endoscope image display device that reads captured image data in which a captured image output from an endoscope is recorded and displays the captured image.

  Endoscopes that obtain images by irradiating a subject with white illumination light to obtain images are widely used. In such an endoscope, in addition to normal light observation using visible light, narrow-band light (special light) with a visible short wavelength is irradiated to form fine patterns on the surface of capillaries and mucous membranes on the surface of living tissue. There is one capable of performing narrow-band light observation with highlighting (for example, see Patent Document 1).

  In general, light with a short visible wavelength (for example, purple or blue light) has a low depth of penetration into living tissue, and light with a long visible wavelength (for example, red light) has a deep depth of penetration into living tissue. In normal observation using white illumination light including long wavelength light, an image including reflected light from a relatively deep region of biological tissue is observed, whereas in special light observation, short wavelength light is used. Therefore, an image of reflected light from the tissue surface layer is mainly observed. Accordingly, both observation images are different even at the same observation position, and are used by appropriately switching during endoscopic diagnosis.

JP 2006-68113 A

  The illumination light at the time of narrow-band light observation contains a lot of purple and blue B light components, and thus the captured image is an image having a different color from the white illumination image at the time of normal observation. For this reason, if an image at the time of narrow-band light observation is subjected to image processing using various image processing algorithms for a normal observation image prepared in advance, the image luminance value is broken and the intended image is not obtained. Patent Document 1 describes that different white balance correction processing is performed for normal light and narrowband light. However, the image captured during narrowband light observation differs in color from the image captured during normal observation due to the difference in the spectrum of illumination light, and even if white balance is used, the difference in color is completely eliminated. It is difficult.

  In addition, there is an endoscope system that records a moving image output from an endoscope on a recording device and performs secondary interpretation after the examination. Generally, a moving image recorded on the recording device is a narrowband light observation. Either the time image or the normal observation image is only recorded. For this reason, even if it is desired to make the color of the image observed during narrow-band light observation the color tone of the image during normal observation using white light and to compare the two images, it is not possible in practice. Thus, even if an image at the time of narrow-band light observation is recorded, the actual situation is that there are many restrictions on its use range.

  In the present invention, even a recorded image using special light such as when observing narrow-band light can be easily converted into a color tone of an image during normal observation and displayed, thereby enabling comparison between images and various image processing. It is an object of the present invention to provide an endoscopic image display apparatus that can improve the accuracy of endoscopic diagnosis.

The present invention has the following configuration.
An endoscope that reads out captured image data including a captured image that is output from the endoscope and is captured by irradiating the subject with illumination light, and that reproduces and displays the captured image of the read captured image data by changing the color tone An image display device,
The illumination light is light in which each light amount of white illumination light and light having a center wavelength of 360 to 470 nm is set to a desired light amount ratio,
The captured image data includes information on the captured image including intensity information of a plurality of basic color components including blue, and information on an imaging condition including the light amount ratio at the time of capturing the captured image.
An intensity changing unit that changes only the intensity of the blue basic color component among the plurality of basic color components in response to the light intensity ratio read from the captured image data;
An endoscopic image display device comprising:

  According to the present invention, even a recorded image using special light such as during narrow-band light observation can be easily converted into the color tone of an image during normal observation and displayed. Image processing can be applied, and the accuracy of endoscopic diagnosis can be improved.

It is a figure for demonstrating embodiment of this invention, and is a block block diagram of an endoscope apparatus. It is an external view as an example of the endoscope apparatus shown in FIG. It is a graph which shows each spectral profile of the illumination light radiate | emitted from an irradiation port with the purple laser beam from a purple laser light source, and the blue laser beam from a blue laser light source. It is explanatory drawing which represented typically the blood vessel of the mucous membrane surface layer of a biological tissue. (A) is a schematic display example of an observation image by an endoscope apparatus, and is an explanatory view showing an observation image when narrow-band light containing many visible short wavelength components is used as illumination light, and (B) shows white light. It is explanatory drawing which shows the observation image at the time of setting it as illumination light. It is a block diagram of an endoscopic image display apparatus. It is a graph which shows the spectral profile of the illumination light at the time of narrow-band light observation. It is a graph which shows the spectral sensitivity characteristic of an image sensor. It is explanatory drawing which shows the correction coefficient with respect to B, G, R. It is a graph which shows the spectral profile of the illumination light with respect to the image equivalent to the captured image data after intensity | strength change. It is explanatory drawing which shows the inspection order recorded in an inspection order database, and its content. It is a graph which shows the relationship between the total lighting time of a laser diode, and emitted light intensity. It is a principal part block diagram which shows the other structural example of a light source device.

Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.
FIG. 1 is a diagram for explaining an embodiment of the present invention, and is a conceptual block diagram of an endoscope apparatus. FIG. 2 is an external view as an example of the endoscope apparatus shown in FIG.
As shown in FIGS. 1 and 2, the endoscope apparatus 100 includes an endoscope 11 and an endoscope control apparatus 13 to which the endoscope 11 is connected. The endoscope 11 is an electronic endoscope having an illumination optical system that emits illumination light from the distal end of the endoscope insertion portion 15 and an imaging optical system that includes an imaging element 17 that images an observation region. The endoscope 11 is detachably connected to the endoscope control device 13 via connector portions 19A and 19B. The endoscope control device 13 is connected to a display unit 21 that displays image information transmitted from the endoscope 11 and an input unit 23 that receives an input operation.

  As shown in FIG. 2, the endoscope 11 includes an endoscope insertion unit 15 that is inserted into a subject, and an operation unit 25 that performs an operation for bending and observing the distal end of the endoscope insertion unit 15. And connector portions 19A and 19B connected from the operation portion 25 via the universal cord 27. Although not shown in the drawing, various types of channels such as a forceps channel for inserting a tissue collection treatment tool and a channel for air supply / water supply are provided inside the endoscope insertion portion 15.

  The endoscope insertion portion 15 includes a flexible soft portion 31, a bending portion 33, and an endoscope distal end portion (hereinafter also referred to as a distal end portion) 35. As shown in FIG. 1, the endoscope distal end portion 35 has irradiation ports 37A and 37B for irradiating light to the observation region, a CCD (Charge Coupled Device) image sensor or CMOS for acquiring image information of the observation region. (Complementary Metal-Oxide Semiconductor) An image sensor 17 such as an image sensor is disposed. An objective lens unit 39 is attached in front of the optical path of the image sensor 17.

  The bending portion 33 is provided between the flexible portion 31 and the distal end portion 35 and can be bent by a turning operation of the angle knob 41 disposed in the operation portion 25. The bending portion 33 can be bent in an arbitrary direction and an arbitrary angle, and can direct the light emission direction of the irradiation ports 37A and 37B of the endoscope distal end portion 35 and the observation direction of the imaging element 17 to a desired observation site. it can. Although illustration is omitted, a cover glass and a lens are arranged outside the irradiation ports 37A and 37B of the endoscope insertion portion 15.

  In addition to the angle knob 41 described above, the operation unit 25 is provided with a switch 43 having various functions, and an observation mode changeover switch 45 shown in FIG.

  The endoscope control device 13 includes a light source device 47 that generates illumination light to be supplied to the irradiation ports 37A and 37B of the endoscope distal end portion 35, and a processor 49 that performs image processing on an image signal from the imaging device 17, and a connector. The endoscope 11 is connected via the sections 19A and 19B. The display unit 21 and the input unit 23 are connected to the processor 49. The processor 49 performs image processing on the imaging signal transmitted from the endoscope 11 based on an instruction from the operation unit 25 or the input unit 23 of the endoscope 11, and generates and supplies image data to the display unit 21. To do.

  The light source device 47 includes a blue laser light source LD1 which is a semiconductor light emitting element having a central wavelength of 445 nm and a violet laser light source LD2 which is a semiconductor light emitting element having a central wavelength of 405 nm as light emission sources. The light emission of each of the light sources LD1 and LD2 is individually controlled by the light source control unit 51, and the light quantity ratio between the emitted light of the blue laser light source LD1 and the emitted light of the violet laser light source LD2 can be freely changed. . That is, the light source control unit 51 can freely control the color tone of the illumination light.

  As the blue laser light source LD1 and the violet laser light source LD2, a broad area type InGaN laser diode can be used, and an InGaNAs laser diode or a GaNAs laser diode can also be used. Moreover, the structure using light-emitting bodies, such as a light emitting diode, may be sufficient as the said light source.

  Laser light emitted from each of the light sources LD1 and LD2 is input to an optical fiber by a condensing lens (not shown), and is connected to a connector section via a combiner 53 that is a multiplexer and a coupler 55 that is a duplexer. It is guided to 19A.

  The laser beam obtained by combining the blue laser beam having the central wavelength of 445 nm and the purple laser beam having the central wavelength of 405 nm supplied to the connector unit 19A is guided to the distal end portion 35 of the endoscope by the optical fibers 57A and 57B. The Then, the blue laser light excites the phosphor 59 which is a wavelength conversion member disposed at the light emitting ends of the optical fibers 57A and 57B of the endoscope distal end portion 35 to generate fluorescence. A part of the blue laser light passes through the phosphor 59 as it is and is emitted as white illumination light together with the aforementioned fluorescence. On the other hand, the violet laser light is transmitted without strongly exciting the phosphor 59 and is emitted as illumination light having a narrow band wavelength.

  FIG. 3 shows spectral profiles of illumination light emitted from the irradiation ports 37A and 37B by the violet laser light from the violet laser light source LD2 and the blue laser light from the blue laser light source LD1. In the figure, the purple laser beam is represented by an emission line having a center wavelength of 405 nm, and the blue laser beam is represented by an emission line having a center wavelength of 445 nm. Further, the light excited and emitted by the phosphor 59 by the blue laser light has a spectral intensity distribution in which the emission intensity increases in a wavelength band of approximately 450 nm to 700 nm. White illumination light is formed by the profile of the excitation light and blue laser light.

  Here, the white light referred to in this specification is not limited to one that strictly includes all wavelength components of visible light, and may be any light that includes light in a specific wavelength band such as R, G, and B, for example. For example, light including a wavelength component from green to red, light including a wavelength component from blue to green, and the like are included in a broad sense.

The phosphor 59 absorbs a part of blue laser light and emits a plurality of kinds of phosphors that emit green to yellow light (for example, YAG phosphors, phosphors including BAM (BaMgAl 10 O 17 ), etc.). Consists of including. As a result, green to yellow excitation light using blue laser light as excitation light and blue laser light that is transmitted without being absorbed by the phosphor 59 are combined into white (pseudo-white) illumination light.

  Returning again to FIG. As described above, the excitation light emitted from the blue laser light and the phosphor 59 (white illumination light) and the illumination light (narrowband light) formed by the violet laser light are set to a desired light quantity ratio by the light source control unit 51. The illuminated light is emitted from the endoscope distal end portion 35 toward the observation region of the subject. The state of the observation area irradiated with the illumination light is imaged on the image sensor 17 by the objective lens unit 39 and imaged. That is, the obtained captured image data is image data captured using illumination light of a spectral profile including laser light and light obtained by exciting and emitting phosphors with the laser light.

  An image signal of a captured image output from the image sensor 17 after imaging is transmitted to the A / D converter 63 through the scope cable 61 and converted into a digital signal, and the endoscope control unit of the processor 49 via the connector unit 19b. 65 is input. The endoscope control unit 65 sends the input digital image signal to the image processing unit 67, and the image processing unit 67 converts the digital image signal into image data and performs appropriate image processing, thereby performing an endoscopic image. Generate data. Then, the endoscope control unit 65 outputs the obtained endoscopic image data to the display unit 21 as an endoscopic observation image for display, and causes the storage unit 69 including a memory and a storage device as necessary. Remember.

  The storage unit 69 may be built in the processor 49 as illustrated, may be connected to the processor 49 via a network, or may be built in a server 71 connected to the network.

  FIG. 4 is an explanatory diagram schematically showing blood vessels on the surface of the mucous membrane of a living tissue. It has been reported that the surface layer of the mucosa of the living tissue is formed between the blood vessel B1 of the deep mucosa and the capillary blood vessel B2 such as a resinous vascular network to the surface of the mucosa, and the lesion of the living tissue appears in the fine structure such as the capillary blood vessel B2. Has been. Therefore, in endoscopic examinations, capillary blood vessels on the mucosal surface layer are image-enhanced and observed, and early detection of micro-lesions and diagnosis of lesion areas have been attempted.

  When illumination light enters a living tissue, the incident light propagates diffusively through the living tissue, but the absorption and scattering characteristics of the living tissue have wavelength dependence, and the shorter the wavelength, the stronger the scattering characteristics. Tend. That is, the depth of light changes depending on the wavelength of illumination light. Therefore, blood vessel information from capillaries on the mucosal surface layer is obtained when the illumination light is in the wavelength region λa near 400 nm, and blood vessel information including deeper blood vessels is obtained in the wavelength region λb near the wavelength of 500 nm. Therefore, a light source with a central wavelength of 360 to 800 nm, preferably 365 to 515 nm, is used for blood vessel observation of a living tissue, and a light source with a central wavelength of 360 to 470 nm, preferably 400 to 420 nm, is used for observation of a surface blood vessel. It is done. In addition, a fine pattern on the surface of the mucous membrane of a living tissue can be highlighted as in the case of capillaries in the above wavelength range.

  As shown in FIGS. 5 (A) and 5 (B), a schematic display example of an observation image by an endoscope apparatus is shown. When narrow-band light containing a lot of visible short wavelength components is used as illumination light, the fineness of the mucous membrane surface layer is reduced. An image in which fine capillaries and fine patterns on the surface of the mucous membrane were clearly projected was obtained (FIG. 5A), and when the illumination light was white light, a blood vessel image of a relatively deep mucosa was projected. An overall image of the affected area is obtained (FIG. 5B).

  In other words, in the observation image irradiated with white illumination light and narrow band light simultaneously, the fine blood vessel on the surface of the mucosa of the living tissue and the fine pattern on the surface of the mucosa are emphasized, that is, an image that makes it easy to specify the properties and observation position of the affected part, This is an observation image that facilitates endoscopic diagnosis of the affected area. Therefore, in the endoscope apparatus 100 having the configuration shown in FIG. 1, the respective emitted light amounts of white light (blue laser light and phosphor emission) and narrow-band light (purple laser light) emitted from the endoscope distal end portion 35. Can be continuously changed independently by the light source controller 51 so that the reflected light of both illumination lights is included in one frame of the captured image.

  The ratio of the amount of emitted light between the white illumination light and the narrow band light is set to an appropriate ratio such as, for example, white illumination light: narrow band light = 1: 4 to 1: 8, thereby clearly observing the observation site with white illumination. In this way, an observation image can be obtained that can easily observe the fine blood vessel structure and the pits by emphasizing the fine pattern on the surface blood vessels and the mucous membrane surface with the narrow band light.

Next, description will be given of storing endoscope image data captured by the endoscope apparatus 100 having the above-described configuration in a storage unit and displaying image information obtained by performing an image operation on the stored endoscope image data. To do.
FIG. 6 is a block diagram of the endoscopic image display apparatus. An endoscope image display device 200 is connected to the network to which the endoscope device 100 is connected. The endoscopic image display device 200 is a device that reads captured image data in which a captured image output from the endoscope 11 is recorded, and reproduces and displays the captured image as it is or with appropriate arithmetic processing.

  The endoscopic image display device 200 includes intensity changing means for selectively reducing the intensity of the specific color component of the captured image data, in addition to reproducing the captured image data and displaying it as recorded. The image at the time of narrow-band light observation using the above-described narrow-band light can be displayed by changing the color tone to that at the time of white light observation.

  The endoscopic image display device 200 includes a control unit 81, an image analysis unit 83 that analyzes captured image data, an intensity changing unit 85 that changes the intensity of a specific color component of the captured image based on the analysis result, and an intensity. The changing unit 85 includes a correction value storage unit 87 in which correction values for increasing or decreasing a correction coefficient for changing the intensity of the specific color component are stored. The endoscopic image display apparatus 200 includes an input unit 89 that inputs various instructions to the control unit 81 and a display unit 91 that displays an image after intensity change.

  Now, it is assumed that captured image data obtained by imaging with illumination light including narrow-band light by the endoscope apparatus 100 is stored in the storage unit 69A of the server 71 connected to the endoscope apparatus 100 via a network. . Here, a process in which the endoscope image display apparatus 200 reads captured image data from the storage unit 69A, performs a desired image calculation on the captured image data, and displays the captured image data on the display unit 91 will be described below.

  The endoscopic image display device 200 selects and reads out desired captured image data from a plurality of captured image data groups from the storage unit 69A. The captured image data is still image or moving image data having a plurality of basic color components including blue (B), green (G), and red (R), and each of B, G, and R intensity values ( (Luminance value). In the case of captured image data recorded during narrow-band light observation, the captured image data generally has a higher intensity level than the R and G values.

  That is, at the time of narrow band light observation, illumination light having a distribution profile as shown in FIG. 7 is irradiated to generate captured image data. Therefore, the captured image data is narrow band light (particularly purple light with a center wavelength of 405 nm). This component is higher in intensity than other wavelength bands. Therefore, the captured image at the time of narrow-band light observation is a bluish image.

  When such a bluish captured image is processed by various image processing algorithms for a normal observation image prepared in advance, that is, for a white illumination image, an image luminance value collapses or the like occurs, and an intended image is obtained. Don't be. In addition, there are cases where it is desired to view a bluish captured image at the time of narrow band light observation in the color tone at the time of normal observation. Therefore, the endoscope image display apparatus 200 of this configuration selectively reduces the intensity of a specific color component corresponding to relatively strong illumination light, even for captured image data captured during narrowband light observation. Thus, a function of changing the color tone of the captured image obtained by pseudo white light illumination is provided. Thereby, the captured image data at the time of narrow band observation is converted into the color tone at the time of normal observation, and the image at the time of narrow band light observation and the image at the time of normal observation at the same position can be compared and observed. In addition, image processing using various image processing algorithms can be performed normally.

  Specifically, as shown in FIG. 8 showing the spectral sensitivity characteristics of the image sensor 17, in the illumination light at the time of narrow band light observation of the spectral profile shown in FIG. 7, the B light component detected by the image sensor is G light, High intensity level for R light. In view of this, the captured image data at the time of narrow-band light observation obtained from the image sensor is processed as follows to change the color tone of the image.

Fbp ij the B color component of the captured image data, FGP the G color component ij, and R color component Frp ij, FBQ the B color component of the captured image data after color change ij, Fgq ij a G color component, R color when the component and Frq ij, captured image data after color change (Fbp ij, Fgp ij, Frp ij) , and using the correction coefficient K (1) ~ (3) obtained from the equation. Here, i and j are indices representing the pixel position of the captured image.
Fbq ij = Kb · Fbp ij ··· (1)
Fgq ij = Kg · Fgp ij (2)
Frq ij = Kr · Frp ij (3)

  In the above equation, the correction coefficients Kb, Kg, and Kr are set so that the intensity value of the B color component of the captured image data (Fbp, Fgp, Frp) after the color tone change is selectively reduced. For example, the target value for intensity reduction for the B color component is set to at least one intensity of G color and R color other than B color. In the above example, Kb is set in a range of 1/4 to 1/8, and Kg and Kr are set to 1, as shown in FIG. 9, corresponding to the ratio of the amount of emitted light between white illumination light and narrowband light. Set.

  An image whose color tone has been changed by the correction coefficient Kb is equivalent to an image captured by illumination light having a spectral profile as shown in FIG. That is, when the changed captured image data is irradiated with the light amount of the narrowband light component near the center wavelength of 405 nm shown in FIG. 7 selectively reduced and the illumination light is irradiated as a flat spectral profile close to white light. The image is close to the captured image. In other words, the value of Kb is set to a value that can convert captured image data in which the B light component at the time of narrow-band light observation is enhanced to captured image data at the time of observation with white illumination light.

  The above process will be described with reference to FIG. In the endoscopic image display apparatus 200 shown in FIG. 6, when there is a request for intensity change processing from the input unit 89, the image analysis unit 83 performs B on the captured image data read from the storage unit 69 </ b> A of the server 71. By analyzing the intensity difference between the color component, the G color component, and the R color component, a specific color component for reducing the intensity is determined from the basic colors of the captured image data. In the captured image at the time of narrow band light observation, the blue component is the specific color component.

  The intensity changing unit 85 changes the intensity for the specific color component determined by the image analyzing unit 83 based on the above equations (1) to (3). The intensity changing unit 85 generates a captured image signal whose intensity of the specific color component is changed, and the control unit 81 converts the captured image signal into a display signal and causes the display unit 91 to display the signal.

  The correction coefficients Kb, Kg, and Kr can be arbitrarily changed by operating the input unit 89, in addition to setting predetermined predetermined values. For example, the input unit 89 can be constituted by a rotary switch, a slide switch, or the like, and the correction coefficient can be changed stepwise by operating the switch. Further, if a volume switch or the like is used, it can be continuously increased or decreased to an arbitrary value. When the correction coefficient is set by the input unit 89, the input unit 89 can be operated while observing the image displayed on the display unit 91, and can be adjusted while visually confirming the degree of intensity change of the specific color component. Can be easily adjusted to the desired image.

  By making the intensity of the specific color component arbitrarily changeable, when changing the intensity of the blue component of the captured image data in the narrowband light observation as described above, the state of microvessels that differ in the depth direction from the tissue surface layer It can be confirmed on the image. Thereby, the three-dimensional distribution of the blood vessel in the patient's living tissue can be examined, and the diagnostic accuracy is improved.

  In addition, when the captured image data is image data captured using illumination light having a broad spectral profile including narrow-band light by laser light and light obtained by exciting and emitting phosphors with this laser light, laser light It becomes easy to adjust the intensity level of only the narrow-band light component. For example, when obtaining captured image data with an imaging device that detects a plurality of basic color components, narrowband light is not detected across the plurality of basic color components, and light that is excited and emitted from a phosphor Can be included in only one of the different basic color components (for example, blue). As a result, it is possible to easily perform intensity correction only for the basic color component including narrowband light.

  In addition, the correction value storage unit 87 stores table information for determining the correction coefficients Kb, Kg, and Kr. The correction coefficients Kb, Kg, and Kr are determined by the operator of the endoscope image display apparatus 200, and the table information is used to determine the values of the correction coefficients Kb, Kg, and Kr that are determined by the endoscope. And an increase / decrease correction corresponding to the imaging condition, and a more appropriate intensity change is possible.

For example, the following cases can be cited as examples of correcting the values of the correction coefficients Kb, Kg, and Kr.
1) The correction coefficient is increased or decreased in accordance with the observation site of the subject displayed in the captured image data.
2) The correction coefficient is increased or decreased according to the calibration result of the imaging optical system of the endoscope apparatus 100.
3) The correction coefficient is increased or decreased according to the total lighting time of the light sources LD1 and LD2 of the light source device 47.

  Information on the observation site of the subject, information on the calibration result, and information on the total lighting time are recorded in the header portion of the data recording structure of the captured image data when the captured image data is recorded in the storage unit 69A. Keep it.

  The observation site of the subject is recorded by referring to the examination order database 72 of the server 71 when the captured image data captured by the endoscope apparatus is recorded in the storage unit 69 shown in FIG. It is determined which examination the captured image data is an image of, and information on the observation region corresponding to the image is written in the header portion of the captured image data.

  As shown in FIG. 11, the examination order recorded in the examination order database and the contents thereof, the captured image data of the examination performed by the endoscope apparatus is associated with the examination No., patient ID, etc. Whether it is of the order is specified. The endoscopic device refers to the contents of the specified examination order, and displays information on the observation site of the examination order, such as “esophagus”, “stomach”, “duodenum”, during the endoscopy or examination. It writes in the header part of captured image data later.

  Then, in the endoscopic image display device 200 that has read the captured image data, the control unit 81 reads information on the observation site from the header portion of the captured image data. The control unit 81 obtains a correction value corresponding to the observation site with reference to the correction value storage unit 87. In the correction value storage unit 87, the color of the image varies depending on the observation site of the patient. Therefore, in the “stomach” that has a strong reddish color, the correction value that decreases the intensity of the R color component, and the “duodenum” that increases the yellowish color. Then, correction values for reducing both the intensity of the G component and the R color component are registered in advance. That is, a suitable correction value is obtained from the correction value storage unit 87 in accordance with the observation site of the captured image data, and the intensity reduction target value for the specific color component of the captured image data is corrected based on this correction value. That is, the specific color component is specified, and the correction coefficients Kb, Kg, and Kr once set are increased or decreased by the correction value corresponding to the observation region.

  Next, a case where the correction coefficient is increased or decreased according to the calibration result of the imaging optical system will be described. In the white balance adjustment, a cylindrical white cap with a white inside is attached to the tip of the endoscope insertion portion 15 (see FIG. 2) before endoscopic examination, and imaging is performed by irradiating predetermined illumination light. The balance of the intensity values of the B color component, the G color component, and the R color component is adjusted so that the color tone of the captured image at that time is displayed in an accurate white color.

  The storage unit 69 (see FIG. 1) stores the set white balance information, and the image processing unit 67 refers to the white balance information for the image signal output from the image sensor 17 and always provides an appropriate color balance. Correct so that

  However, when the intensity of a specific color component is selectively reduced, it is not necessary to adjust the white balance of the captured image data. Rather, the intensity before white balance adjustment is used in that an accurate detection signal from the image sensor is used as it is. It is desirable to return to the value. Therefore, in order to change the captured image data recorded after the white balance adjustment to each intensity value before the white balance adjustment, the white balance information is read from the header portion of the captured image data, and the intensity value of the B color component described above is read. Arithmetic processing is performed together with processing that selectively decreases. By this processing, the intensity change due to the white balance adjustment is canceled, and more accurate captured image information can be displayed.

  Next, a case where the correction coefficient is increased or decreased according to the total lighting time of the light sources LD1 and LD2 of the light source device 47 will be described. The light sources LD1 and LD2 shown in FIG. 1 are controlled to be turned on by the control from the light source control unit 51. The timer 95 measures the time when the light sources LD1 and LD2 are turned on by the light source controller 51. In general, a light emitting element such as a laser diode has a characteristic in which a change in light emission intensity due to deterioration with time is recognized, and the light emission intensity gradually decreases as the lighting time increases.

  FIG. 12 shows the relationship between the total lighting time of the laser diode and the emission intensity. As shown in the figure, when the emission intensity is Pa at the total lighting time ta, when the correction coefficients Kb, Kg, Kr for reducing the specific color component are determined based on the emission intensity, When the emission intensity decreases to Pb at time tb, the correction coefficients Kb, Kg, and Kr deviate from appropriate values.

  Therefore, in order to make the correction coefficients Kb, Kg, and Kr appropriate according to the light amount of the light source at the time of inspection, information on the total lighting time is read from the header portion of the captured image data. Based on the relationship between the total lighting time and the light emission intensity stored in the storage unit 69 (see FIG. 1), a correction value corresponding to the decrease in the light emission intensity is obtained, and the correction coefficients Kb, Kg, Kr once set are obtained. The correction value is increased or decreased by this correction value. By this processing, accurate captured image information can always be displayed without being affected by the deterioration of the light source over time.

In the light source device 47 of the endoscope apparatus 100 described above, the narrow band light is generated by the violet laser light. However, the narrow band light can be generated by a light emitting diode, and other configurations can be adopted.
FIG. 13 shows another configuration example of the light source device. The light source device 47A includes a white light source 101 such as a xenon lamp, a halogen lamp, or a metal halide lamp, a movable slit 103 for adjusting the amount of light, a filter unit 109 that rotationally drives a rotary filter 107 by a motor 105, a white light source 101, and a movable slit. 103, and a light source control unit 111 for controlling the motor 105. The rotary filter 107 includes an R filter, a G filter, and a B filter for extracting each color light, and a special light filter for extracting the above-described narrow band light with a visible short wavelength.

  The light transmitted through the rotary filter 107 is incident on the optical fiber bundle 115 through the condenser lens 113 and guided to the distal end portion 35 of the endoscope 11 through the optical fiber bundle 115. And it irradiates to a subject from the endoscope front-end | tip part 35 as illumination light. The imaging optical system is the same as that shown in FIG.

  In this configuration example, an R image, a G image, a B image, and a narrowband light image are sequentially acquired by capturing images in synchronization with the rotation of the rotation filter 107, and these images (R image + G image + B image, G Image + narrowband light image, etc.) and a frame sequential optical system that generates a single color image.

  The captured image data obtained when performing narrow-band light observation using this light source device has a high intensity of the B color component due to the narrow-band light. Therefore, as described above, by performing processing for selectively reducing the intensity of the B color component with respect to the intensity of the other G and R color components, the image can be changed to an image observed during normal observation.

  The present invention is not limited to the above-described embodiments, and those skilled in the art can change or apply the present invention based on the description of the specification and well-known techniques. included. For example, the intensity of the blue component of the captured image data is selectively reduced for images during narrowband light observation, but even when the illumination light of a wavelength band other than blue light is strongly irradiated, the light component that is strongly irradiated By reducing the detection intensity, the same effects as described above can be obtained.

As described above, the following items are disclosed in this specification.
(1) An endoscope image display device that reads captured image data in which a captured image output from an endoscope is recorded and reproduces and displays the captured image,
The captured image data has intensity information of a plurality of basic color components,
An endoscope image display device comprising intensity changing means for selectively reducing the intensity of a specific color component of the captured image data.
According to this endoscopic image display device, even if the captured image data is image data captured using illumination light whose emitted light intensity in a specific wavelength band is increased, the intensity (luminance value) of the specific wavelength band component ) Can be selectively reduced so that it can be converted into a color tone during normal observation and displayed. Thereby, comparison between images and application of various image processing can be performed, and the accuracy of endoscopic diagnosis can be improved.

(2) The endoscope image display device according to (1),
An endoscopic image display device in which the specific color component is a blue component.
According to this endoscopic image display device, by reducing the blue basic color component, for example, it is possible to display an image in which the B light component is selectively reduced in the illumination light during narrowband light observation.

(3) The endoscope image display device according to (2),
An endoscope image display device, wherein the intensity of the blue component includes the intensity of a light component in a wavelength band of a wavelength of 400 nm to 420 nm.
According to this endoscopic image display device, it is possible to change the intensity of captured image data in which highlights are displayed in particular on capillaries on the surface of biological tissue and fine patterns on the mucous membrane surface.

(4) The endoscope image display device according to any one of (1) to (3),
An endoscopic image display device comprising: an input unit in which the intensity changing unit arbitrarily sets a target value for intensity reduction for the specific color component.
According to this endoscopic image display device, it is possible to freely change the degree of highlighting of a specific color component and cancel the highlighting.

(5) The endoscope image display device according to any one of (1) to (4),
An endoscopic image display device in which the intensity changing means uses an intensity for at least one basic color other than the specific color as a target value for reducing the intensity of the specific color component.
According to this endoscopic image display device, by reducing the intensity of the specific color component to the same level as the intensity of any other basic color, it is possible to approximate the same color tone as the captured image during normal observation.

(6) The endoscope image display device according to any one of (1) to (5),
The captured image data includes information on the intensity of the plurality of basic color components, and information on imaging conditions for the captured image data,
A correction value storage unit in which the intensity changing unit stores a correction value for correcting a target value for intensity reduction of the specific color component corresponding to the imaging condition;
The correction value corresponding to the imaging condition information read from the captured image data is obtained from the correction value storage unit, the intensity reduction target value is corrected with the obtained correction value, and the intensity of the specific color component is calculated. An endoscopic image display device comprising: an intensity changing unit for changing.
According to this endoscopic image display device, the intensity can be changed in accordance with the imaging condition by changing the target value for reducing the intensity of the specific color component in accordance with the imaging condition for the captured image data.

(7) The endoscope image display device according to (6),
An endoscope image display device in which the information on the imaging condition is information on an observation site of a subject with respect to the captured image data.
According to this endoscopic image display device, the degree of reduction in the intensity of the captured image data is adjusted according to the observation site of the subject, so that an appropriate intensity change can be made for each observation site.

(8) The endoscope image display device according to (6),
An endoscope image display device, wherein the information on the imaging condition is information on a white balance adjustment value for adjusting a white balance of a captured image output by the endoscope.
According to this endoscope image display device, the degree of decrease in intensity of the captured image data is adjusted according to the adjustment value of the white balance of the endoscope, so that the intensity change due to the white balance adjustment is canceled, More accurate captured image information can be displayed.

(9) The endoscope image display device according to (6),
An endoscope image display device in which the information of the captured image is lighting time information indicating a total lighting time of a light source included in the endoscope.
According to this endoscopic image display device, accurate captured image information can always be displayed without being affected by the deterioration of the light source with time.

(10) The endoscope image display device according to any one of (1) to (9),
An endoscope image display device, wherein the captured image data is image data captured using illumination light having a spectral profile including laser light and light obtained by exciting and emitting phosphors with the laser light.
According to this endoscopic image display device, since it is image data captured by irradiating a combination of narrow-band light from laser light and illumination light of a broad spectral profile that is light emitted from a phosphor, it is narrow. It becomes easy to adjust the intensity level of only the band light component. For example, in the case where captured image data is obtained by an image sensor that detects a plurality of basic color components, narrowband light is not detected across the plurality of basic color components, and light that is excited and emitted from a phosphor Can be included in only one of the different basic color components. As a result, it is possible to easily perform intensity correction of only the basic color component included in the narrowband light.

DESCRIPTION OF SYMBOLS 11 Endoscope 13 Endoscope control apparatus 17 Image pick-up element 47 Light source device 49 Processor 51 Light source control part 57A, 57B Optical fiber 59 Phosphor 65 Endoscope control part 67 Image processing part 69 Storage part 71 Server 81 Control part 83 Image Analysis unit 85 Intensity changing unit 87 Correction value storage unit 91 Display unit 95 Timer 100 Endoscope device 200 Endoscope image display device LD1 Blue laser light source LD2 Purple laser light source

Claims (6)

  1. An endoscope that reads out captured image data including a captured image that is output from the endoscope and is captured by irradiating the subject with illumination light, and that reproduces and displays the captured image of the read captured image data by changing the color tone An image display device,
    The illumination light is light in which each light amount of white illumination light and light having a center wavelength of 360 to 470 nm is set to a desired light amount ratio,
    The captured image data includes information on the captured image including intensity information of a plurality of basic color components including blue, and information on an imaging condition including the light amount ratio at the time of capturing the captured image.
    An intensity changing unit that changes only the intensity of the blue basic color component among the plurality of basic color components in response to the light intensity ratio read from the captured image data;
    An endoscopic image display device comprising:
  2. The endoscope image display device according to claim 1,
    A correction value storage unit storing a correction value for correcting an intensity reduction target value for reducing the intensity of the blue basic color component corresponding to the light amount ratio;
    The intensity changing unit obtains the correction value corresponding to the light amount ratio read from the captured image data from the correction value storage unit, and corrects the intensity reduction target value of the blue basic color component with the obtained correction value. An endoscopic image display device that changes only the intensity of a blue basic color component among the plurality of basic color components.
  3. The endoscopic image display device according to claim 1 or 2,
    Intensity of basic color component of the blue, the endoscopic image display device the intensity of light components in a wavelength band of wavelength 400nm to 420 nm.
  4. An endoscopic image display device according to any one of claims 1 to 3,
    An endoscope image display device in which the light having a central wavelength of 360 to 470 nm is laser light.
  5. An endoscopic image display device according to any one of claims 1 to 3,
    The endoscope image display device, wherein the light having a central wavelength of 360 to 470 nm is light generated by a light emitting diode.
  6. An endoscope image display device according to any one of claims 1 to 5,
    The endoscope image display device, wherein the white illumination light is illumination light having a spectral profile including laser light and light obtained by exciting and emitting a phosphor with the laser light.
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