JP5588131B2 - Liquid supply tool - Google Patents

Description

  The present invention relates to a liquid supply tool.

  Conventionally, a method of mixing two or more kinds of liquids and spraying them onto an affected area to form an adhesion preventing material, a biological tissue adhesive or the like has been known, and an applicator for that purpose has been developed.

  Such an applicator has a configuration in which components that coagulate when mixed, for example, a solution containing thrombin and a solution containing fibrinogen are separated from each other, sent to the vicinity of the affected area, and applied while mixing in the affected area. is there.

  As a conventional applicator, an applicator main body loaded with two syringes filled with different types of liquids, and an operation member (a plunger) connected to each syringe are operated together. Actuators) and long nozzles (barrels) that eject the liquid that has flowed out of the syringes by pressing the operating member toward the distal direction (see, for example, Patent Document 1).

  In the applicator described in Patent Document 1, for example, when the viscosity of the liquid filled in at least one of the two syringes is relatively high, the viscosity of the liquid is low even if the operation member is pressed. Due to the high cost, there has been a problem that, depending on the operator, the pressing operation is difficult or impossible. In addition, when the viscosities of the liquids of the two syringes are extremely different, the pressing force applied to each pusher by the operating member may not be uniform. Even in this case, it is difficult or impossible to perform the pressing operation. It was.

JP-T-2002-522177

  An object of the present invention is to provide a liquid supply tool capable of easily and reliably performing a pressing operation when pressing an operating member.

Such an object is achieved by the present inventions (1) to (10) below.
(1) A syringe outer cylinder having a mouth portion protruding from the tip, a gasket that is inserted into the syringe outer cylinder and moves along the longitudinal direction thereof, and an operation member that moves the gasket. The liquid supply comprising the first syringe and the second syringe for operating the operation member to discharge the liquid filled in the distal end side space surrounded by the syringe outer cylinder and the gasket from the mouth. Tools,
The syringe outer cylinder is hermetically sealed at its proximal end opening,
The second syringe has a smaller force required to move the gasket when discharging the liquid than the first syringe.
When operating the operation member, gas is supplied into the proximal side space closer to the proximal side than the gasket of the syringe outer cylinder of the first syringe and the second syringe, and the proximal side A press assisting means capable of pressing the gaskets of the first syringe and the second syringe toward the distal direction by pressurizing the space;
The liquid supply unit characterized in that the pressing assisting unit can select whether to operate with respect to the first syringe or to both the first syringe and the second syringe. Ingredients.

(2) an applicator body that holds the first syringe and the second syringe ;
The liquid material supply according to (1), further including a nozzle that ejects the liquid discharged from the mouth portion and applies it to a target site by pressing the operation member toward the distal direction. Ingredients.

(3) The nozzle is connected to gas supply means for supplying gas,
The pressing assist means includes a first gas flow path for supplying a part of the gas supplied from the gas supply means into the proximal end side space of the first syringe, and the second syringe. A second gas flow path for supplying the gas into the proximal end space, and the gas supply to the proximal end space of the second syringe and its stop, provided in the middle of the second gas flow path. The liquid supply tool according to (2), further including a switching unit for switching .

(4) The liquid supply according to (3) , wherein the operation member is configured by a tubular body, and a lumen portion of the tubular body functions as the first gas flow path and the second gas flow path. Ingredients.

(5) The pressing assist means is a through-hole formed in the tubular body, and has a through-hole that is closed when the gas is supplied and opened when the supply is stopped ( The liquid supply tool according to 4).

(6) The liquid supply tool according to (5) , wherein the gas is discharged into the atmosphere through the through hole when the through hole is open.

(7) The liquid supply tool according to any one of (3) to (6), wherein the switching unit is configured to be capable of adjusting a supply amount of the gas .

(8) Any one of the above (1) to (7), wherein the pressing force when the pressing assist means presses the gasket is smaller than the sliding resistance when the gasket slides in the syringe outer cylinder. The liquid supply tool according to 1.

(9) The liquid supply tool according to any one of (1) to (8), wherein the viscosity of the liquid filled in the first syringe is higher than the viscosity of the liquid filled in the second syringe.

(10) The liquid supply tool according to any one of (1) to (9), wherein an inner diameter of the syringe outer cylinder of the first syringe is larger than an inner diameter of the syringe outer cylinder of the second syringe.

  In the liquid supply tool of the present invention, it is preferable that the applicator main body is configured to hold the syringe outer cylinders of the two syringes side by side.

In the liquid supply tool of the present invention, one of the two syringes may have a liquid whose viscosity is higher than that of the other syringe or the outside of the syringe. The inner diameter of the cylinder is larger than the inner diameter of the syringe outer cylinder of the other syringe,
It is preferable that the pressing assist means can select whether to operate with respect to the one syringe or with respect to the two syringes.

  In the liquid supply tool of the present invention, it is preferable that at least one step portion having a top surface and a bottom surface having different heights in the liquid ejection direction is formed on the tip surface of the nozzle. .

  According to the present invention, when the gasket is moved by pressing the operating member, in addition to the pressing force, a force for moving the gasket by the pressing assist means is further generated. Will move. As a result, the pressing operation with respect to the operation member can be performed easily and reliably.

It is a fragmentary longitudinal cross-sectional view (figure which shows a use process in order) which shows 1st Embodiment at the time of applying the liquid supply tool of this invention to an applicator. It is a fragmentary longitudinal cross-sectional view (figure which shows a use process in order) which shows 1st Embodiment at the time of applying the liquid supply tool of this invention to an applicator. It is a perspective view which shows the front-end | tip part (nozzle head) of the nozzle in the applicator shown in FIG. It is a longitudinal cross-sectional view (the figure which shows the time-dependent change of the application | coating state of a nozzle) of the front-end | tip part vicinity of the nozzle in the applicator shown in FIG. It is a longitudinal cross-sectional view (the figure which shows the time-dependent change of the application | coating state of a nozzle) of the front-end | tip part vicinity of the nozzle in the applicator shown in FIG. It is a longitudinal cross-sectional view (the figure which shows the time-dependent change of the application | coating state of a nozzle) of the front-end | tip part vicinity of the nozzle in the applicator shown in FIG. It is a longitudinal cross-sectional view which shows the state which the front-end | tip of the nozzle in the applicator shown in FIG. 1 contact | abutted to the biological body. It is a longitudinal cross-sectional view which shows the operation member of an applicator (2nd Embodiment). It is a fragmentary longitudinal cross-section which shows 3rd Embodiment of an applicator. It is a longitudinal cross-sectional view which shows 4th Embodiment of an applicator. It is a fragmentary longitudinal cross-sectional view (figure which shows a use process in order) which shows embodiment at the time of applying the liquid supply tool of this invention to a syringe. It is a fragmentary longitudinal cross-sectional view (figure which shows a use process in order) which shows embodiment at the time of applying the liquid supply tool of this invention to a syringe. It is a fragmentary longitudinal cross-sectional view (figure which shows a use process in order) which shows embodiment at the time of applying the liquid supply tool of this invention to a syringe.

  Hereinafter, the liquid supply tool of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.

<First Embodiment>
FIG. 1 and FIG. 2 are partial longitudinal sectional views showing the first embodiment when the liquid material supply device of the present invention is applied to an applicator, respectively, and FIG. 3 shows FIG. The perspective view which shows the front-end | tip part (nozzle head) of the nozzle in the applicator shown, FIGS. 4-6 is respectively the longitudinal cross-sectional view of the front-end | tip part of the nozzle in the applicator shown in FIG. FIG. 7 is a longitudinal sectional view showing a state where the tip of the nozzle in the applicator shown in FIG. 1 is in contact with a living body. In the following, for convenience of explanation, the right side in FIGS. 1 to 7 (the same applies to FIGS. 8 to 13) is referred to as “base” or “rear”, and the left side is referred to as “tip” or “front”.

  The applicator 1 shown in FIG. 1 and FIG. 2 is inserted into the abdominal cavity, for example, during laparoscopic surgery, and two kinds of liquids (first liquid L1 and second liquid L2) having different liquid compositions are used. While mixing, the mixture (mixed solution) is applied to a target site such as an organ or abdominal wall.

  The applicator 1 is loaded with a first syringe (liquid supply means) 2 for storing the first liquid L1 and a second syringe (liquid supply means) 3 for storing the second liquid L2. Used. Since the 1st syringe 2 and the 2nd syringe 3 are the substantially the same structures, the 1st syringe 2 is demonstrated typically.

  The first syringe 2 includes an outer cylinder (syringe outer cylinder) 21 and a gasket 24 that can slide in the outer cylinder 21.

  The outer cylinder 21 is composed of a bottomed cylindrical member, and a mouth portion (reduced diameter portion) 22 that is reduced in diameter relative to the body portion of the outer cylinder 21 is integrally formed at the center of the bottom portion on the tip side. ing.

  A flange 23 is integrally formed in the vicinity of the base end opening of the outer cylinder 21 (outer periphery of the rear end). In the present embodiment, the flange 23 of the outer cylinder 21 of the first syringe 2 and the flange 23 of the outer cylinder 21 of the second syringe 3 are integrally formed. Thus, the first syringe 2 and the second syringe 3 constitute a syringe connected body.

  Further, a pusher portion 51a of the operation member 5 to be described later, which moves the gasket 24, is inserted from the proximal end opening of the outer cylinder 21. The base end opening of the outer cylinder 21 is hermetically sealed by a seal member 27. The seal member 27 is a ring-shaped member made of an elastic material (for example, the same material as the gasket 24). The pusher portion 51 a is inserted through the seal member 27, and when the pusher portion 51 a is operated, the outer peripheral surface of the pusher portion 51 a slides in close contact with the inner peripheral surface of the seal member 27. Thereby, the airtightness in the outer cylinder 21 (base end side space 212) is reliably maintained.

  A plurality of stoppers 25 are formed on the inner peripheral surface of the outer cylinder 21 so as to project the rearward movement limit of the gasket 24. The stoppers 25 are arranged at equal intervals along the circumferential direction of the inner peripheral surface of the outer cylinder 21.

A scale indicating the amount of liquid is attached to the outer peripheral surface of the outer cylinder 21.
The constituent material of the outer cylinder 21 is not particularly limited. For example, polyvinyl chloride, polyethylene, polypropylene, cyclic polyolefin, polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile-butadiene- Various resins such as styrene copolymers, polyesters such as polyethylene terephthalate, polyethylene naphthalate, butadiene-styrene copolymers, polyamides (for example, nylon 6, nylon 6,6, nylon 6,10, nylon 12) can be used. However, among them, resins such as polypropylene, cyclic polyolefin, and polyester are preferable because they are easy to mold and have low water vapor permeability. In addition, it is preferable that the constituent material of the outer cylinder 21 is substantially transparent in order to ensure internal visibility.

  In such an outer cylinder 21, a gasket 24 made of an elastic material is accommodated. The gasket 24 can move along the longitudinal direction of the outer cylinder 21. The movement of the gasket 24 is performed by moving the operation member 5 connected to the gasket 24 (pressing operation). When the gasket 24 moves toward the distal direction, the outer peripheral surface of the gasket 24 slides in close contact with the inner peripheral surface of the outer cylinder 21. Accordingly, the first liquid L1 can be pushed out toward the mouth portion 22 while the liquid tightness in the outer cylinder 21 is reliably maintained. The constituent material of the gasket 24 is not particularly limited. For example, various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, silicone rubber, polyurethane, polyester, polyamide, Examples thereof include elastic materials such as various thermoplastic elastomers such as olefins and styrenes, or mixtures thereof.

  Before the first syringe 2 is loaded into the applicator 1, the first liquid L <b> 1 is filled into the front end side space (liquid storage space) 211 surrounded by the outer cylinder 21 and the gasket 24. The second syringe 3 is filled with a second liquid L <b> 2 in a front end side space (liquid storage space) 211 surrounded by the outer cylinder 21 and the gasket 24.

  The first liquid L1 filled in the first syringe 2 and the second liquid L2 filled in the second syringe 3 have different compositions and components.

  In the present invention, the first liquid L1 and the second liquid L2 are appropriately selected according to the application, purpose of use, case, and the like of the applicator 1. For example, when used for administration of a biological tissue adhesive, one of the first liquid L1 and the second liquid L2 is a liquid containing thrombin (solution or the like), and the other is a liquid containing fibrinogen (solution or the like). ).

  In addition, when used for administration of the anti-adhesion material, one of the first liquid L1 and the second liquid L2 is a liquid (solution or the like) containing carboxymethyldextrin modified with a succinimidyl group, and the other is phosphorus It can be set as the liquid (solution etc.) containing disodium oxyhydrogen.

  The first liquid L1 and the second liquid L2 in such a combination are altered, that is, gelled (solidified) when they are mixed. By being gelled, for example, a mixture of the first liquid L1 and the second liquid L2 (hereinafter sometimes referred to as “mixture” or “mixed liquid”) is applied to a living tissue (purpose It is possible to stay securely in the region. In addition, since the mixture remains reliably at the target site, the function as a biological tissue adhesive or an adhesion preventing material can be reliably exhibited at the target site.

  Needless to say, the types and combinations of the first liquid L1 and the second liquid L2 are not limited to those described above.

  The first syringe 2 and the second syringe 3 having such a configuration are each connected to a nozzle 4 which will be described later, and the first flow path 44 of the nozzle 4 is first pressed by operating the operation member 5. The liquid L1 can be easily and reliably supplied to the second flow path 45. The pressing operation of the operation member 5 is manually performed by an operator (user) of the applicator 1. Therefore, the operator can apply the mixture at his / her arbitrary timing.

  The applicator 1 ejects the first liquid L1 and the second liquid L2 together with a sterile gas G (hereinafter simply referred to as “gas G”) (see FIGS. 2 and 5). The gas G atomizes the mixture, and the mixture can be uniformly applied to a target site (target site such as an affected area). The gas G is supplied by a gas cylinder (gas supply means) 300b. The gas cylinder 300b communicates with the nozzle 4 via the tube 302b.

  The gas cylinder 300b is filled with compressed gas G in its internal space, and can supply the gas G flowing at high speed to the applicator 1 (nozzle 4). An openable / closable valve (not shown) for controlling supply / stop of supply of the gas G to the applicator 1 is installed in the middle of the gas cylinder 300b or the tube 302b. When applying the mixture, the valve is opened. The gas G is not particularly limited, and examples thereof include air, an inert gas such as nitrogen, oxygen, carbon dioxide (carbon dioxide gas), and among these, air, which is a gas having poor water solubility, Nitrogen and oxygen are preferred.

  As shown in FIGS. 1 and 2, the applicator 1 includes an applicator main body 7, a nozzle 4 installed on the distal end side of the applicator main body 7, and an operation member installed on the proximal end side of the applicator main body 7. And 5.

  The applicator main body 7 has a syringe holding portion 71 that holds the outer cylinder 21 of the first syringe 2 and the outer cylinder 21 of the second syringe 3.

  The syringe holding part 71 fixes the 1st syringe 2 (outer cylinder 21) and the 2nd syringe 3 (outer cylinder 21) side by side. This syringe holding part 71 is comprised with the member which makes a flat block shape, has the fitting part 711 which opens to the base end surface, and the opening part 22 of each outer cylinder 21 fits.

  When the mouth portion 22 of each outer cylinder 21 is fitted to the fitting portion 711, the mouth portion 22 of the first syringe 2 is connected to the first flow path 44 of the nozzle 4, and the mouth portion of the second syringe 3. 22 is connected to the second flow path 45. As a result, the first liquid L1 can be supplied to the first flow path 44, and the second liquid L2 can be supplied to the second flow path 45 (see FIGS. 2 and 5).

  In addition, the syringe holding part 71 has a connection part 73 constituted by a through-hole penetrating between the two fitting parts 711. The connection part 73 is open to the distal end face and the proximal end face of the syringe holding part 71, and the distal end side part is a nozzle connection part 731 to which the nozzle 4 is connected. The base end side portion of the connection portion 73 is an operation member connection portion 732 to which the operation member 5 is connected. Further, in the middle of the connecting portion 73, an end portion of the tube 302b through which the gas G from the gas cylinder 300b passes is connected. When the gas G that has passed through the tube 302b flows into the connecting portion 73, the gas G is divided into one that goes to the nozzle 4 and one that goes to the operation member 5 (see FIGS. 1 and 2).

  As a constituent material of the syringe holding part 71, for example, various resins as described in the description of the outer cylinder 21 can be used.

  As shown in FIGS. 1 and 2, a nozzle 4 is installed on the distal end side of the applicator main body 7. The nozzle 4 ejects the first liquid L1 and the second liquid L2 (mixture) together with the gas G. The nozzle 4 has a long nozzle body 43 and a nozzle head 42 whose diameter is larger than the outer diameter of the nozzle body 43.

  As shown in FIGS. 4 to 6, the nozzle body 43 includes a first flow path 44 through which the first liquid L <b> 1 supplied from the first syringe 2 passes and a second flow path supplied from the second syringe 3. The liquid channel 41 includes a second channel 45 through which the second liquid L2 passes. Further, the nozzle body 43 has a third flow path 46 through which the gas G supplied from the gas cylinder 300b passes.

  The first flow path 44 and the second flow path 45 through which each liquid passes are each configured by a lumen defined by inner tubes (inner pipes) 44a and 45a. The proximal end portion of the inner tube 44 a constituting the first flow path 44 extends to the fitting portion 711 of the applicator main body 7 to which the mouth portion 22 of the first syringe 2 is connected. Similarly, the inner tube 45a constituting the second flow path 45 has a base end portion extending to the fitting portion 711 to which the mouth portion 22 of the second syringe 3 is connected.

  The first flow path 44 and the second flow path 45 merge with each other at their front end portions (front end portions). As a result, the junction 47 can be provided in the liquid channel 41. As shown in FIG. 5, in this junction 47, the first liquid L1 and the second liquid L2 merge to form a mixed liquid that is uniformly and reliably mixed.

  The joining portion 47 may be an extension of each of the inner tubes, but in the configuration shown in the figure, the joining portion 47 is constituted by a tube (merging portion forming tube) 47a that is separate from the inner tube. ing. The distal end portion 471 of the tube 47a is fitted to the inner peripheral portion 461 of the distal end of an outer tube (outer tube) 46a constituting a third flow path 46 described later. Further, the base end portion 472 of the tube 47a is collectively fitted to the distal end portions 441 and 451 of the inner tubes 44a and 45a constituting the first flow path 44 and the second flow path 45, respectively. As a result, both ends of the tube 47a are supported and fixed securely.

The entire wall portion of the tube 47a is composed of a gas permeable membrane 473.
The gas permeable membrane 473 is permeable to the gas G in the nozzle body 43. As a result, the gas G can flow into the tube 47a (merging portion 47) via the gas permeable membrane 473. Therefore, the gas G that has flowed in is mixed with the first liquid L1 and the first liquid L1 mixed in the merging portion 47. The two liquids L2 are ejected from the ejection port 424 (see FIG. 5). Thereby, a liquid mixture becomes mist-like and is apply | coated to an affected part.

  As described above, since the entire wall portion of the tube 47a is composed of the gas permeable membrane 473, the gas G flows into the tube 47a from any portion in the circumferential direction of the tube 47a via the gas permeable membrane 473. can do. As a result, the gas G can be supplied into the tube 47a without excess or deficiency, so that the mixed liquid ejected from the ejection port 424 is surely atomized. Thus, when the liquid mixture becomes mist-like, the liquid mixture is a mixture of the first liquid L1 and the second liquid L2 uniformly, and is applied to the affected part in a uniformly mixed state. As shown in FIG. 6, when the discharge of the mixed liquid is stopped, the gas G that has flowed in through the gas permeable membrane 473 reliably pushes the mixed liquid in the tube 47a outward. Thereby, it is prevented that a liquid mixture remains in the jet nozzle 424, Therefore, it is prevented that clogging arises in the said jet nozzle 424 (nozzle 4). In addition, the remaining liquid of the mixed liquid (the first liquid L1 and the second liquid L2) is reliably prevented from leaking from the ejection port 424.

  A large number of pores (not shown) are formed in the gas permeable membrane 473 through which such gas G passes. Each pore penetrates the gas permeable membrane 473 in the thickness direction. The average pore diameter of these pores is not particularly limited, but is preferably 2 μm or less, for example. Examples of the air-permeable membrane 473 having such pores include “Pore-Flon tube (TB-0201)” manufactured by Sumitomo Electric Fine Polymer Co., Ltd. This is a gas permeable membrane 473 having an average pore diameter of about 1 μm.

  In addition, by setting the pore diameter to 0.01 to 0.45 μm, the gas G can surely permeate and the gas permeable membrane 473 has a bacteria-impermeable property. Since the gas permeable membrane 473 is impermeable to bacteria, even if the gas G in the gas cylinder 300b is not in a sterile state, fungi in the gas G are removed by the gas permeable membrane 473, and the fungi are removed from the nozzle 4 Inflow is reliably prevented. Thereby, the aseptic mixture can be applied to the affected area.

  Moreover, the film thickness of the ventilation film 473 is not specifically limited, For example, it is preferable that it is 0.1-1 mm, and it is more preferable that it is 0.3-0.8 mm.

Moreover, it is preferable that the area of the ventilation film 473 is 20-200 mm < ² >, and it is more preferable that it is 40-100 mm < ² >.

  The gas permeable membrane 473 is impermeable (water repellency) to the first liquid L1 and the second liquid L2, that is, has hydrophobicity. This reliably prevents the first liquid L1 and the second liquid L2 in the tube 47a from flowing back into the third flow path 46 (outer tube 46a) via the gas permeable membrane 473. Such a gas permeable membrane 473 is made of the hydrophobic material, or the surface thereof is subjected to a hydrophobic treatment. Examples of the hydrophobic material (component material) include polytetrafluoroethylene (PTFE), a copolymer of tetrafluoroethylene and hexafluoropropylene (FEP), and a copolymer of tetrafluoroethylene and perfluoroalkyl vinyl ether ( PFA), polychlorotrifluoroethylene (PCTFE), polyvinylidene fluoride (PVDF), copolymer of ethylene and tetrafluoroethylene (ETFE), copolymer of ethylene and chlorotrifluoroethylene (ECTFE), polypropylene (PP) Etc. As the gas permeable membrane 473, a material obtained by making these materials porous by a stretching method, a microphase separation method, an electron beam etching method, a sintering method, argon plasma particles, or the like is preferably used. The method for the hydrophobization treatment is not particularly limited, and examples thereof include a method of coating the surface of the gas permeable membrane 473 with the hydrophobic material.

  The third flow path 46 through which the gas G passes is located on the outer peripheral side of the inner tubes 44a and 45a constituting the first flow path 44 and the second flow path 45, that is, each inner tube 44a. And a gap defined by the outer tube 46a through which 45a is inserted. The outer tube 46 a has a base end connected to the nozzle connection portion 731 of the applicator main body 7. Further, the distal end 463 of the outer tube 46a (nozzle 4) has a circular shape when viewed from the distal end side, and the center thereof is open (see FIG. 3). The opening functions as an outlet 424 through which the mixed liquid formed by mixing the first liquid L1 and the second liquid L2 in the junction 47 is ejected together with the gas G. Moreover, since the liquid mixture is ejected together with the gas G, it is atomized and applied uniformly to the target portion.

  Further, as shown in FIG. 3, two stepped portions 464 are formed at the tip 463 of the nozzle 4 via the ejection port 424. Each stepped portion 464 is a portion having a top surface 465 and a bottom surface 466 having different heights in the front-rear direction (mixed liquid ejection direction). In the present embodiment, the two step portions 464 share one bottom surface 466. A spout 424 is disposed at the center of the bottom surface 466.

  As shown in FIG. 7, even when the tip 463 of the nozzle 4 comes into contact with, for example, the organ 900 when using the applicator 1, the top surface 465 of each stepped portion 464 is positioned on the bottom surface 466 at the tip 463. Therefore, the jet outlet 424 is prevented from being blocked by the organ 900. As described above, each stepped portion 464 exhibits a function of preventing the ejection port 424 from being blocked by, for example, the organ 900 or the like when the applicator 1 is used.

  As described above, the two stepped portions 464 are disposed to face each other via the ejection port 424, that is, intermittently disposed along the circumferential direction at the outer peripheral portion of the tip 463 of the nozzle 4. Thereby, the jet nozzle 424 is surrounded by the two step portions 464. In addition, each stepped portion 464 has an arc shape along the circumferential direction of the outer peripheral portion of the tip 463 of the nozzle 4 when viewed from the tip side.

  A groove 467 is formed between the two stepped portions 464 thus formed. The groove 467 communicates with the merging portion 47 through the ejection port 424 (see, for example, FIG. 7). Even when the application of the mixed liquid is performed in a state where the tip 463 of the nozzle 4 shown in FIG. 7 is in contact with the organ 900, the mixed liquid containing the gas G in the merging portion 47 passes through the ejection port 424 and the groove 467 in order. Pass through and gushes reliably outward. Further, since the liquid mixture is surely ejected, it is ensured that the liquid mixture flows backward in the merging portion 47 or that the gas G flows backward from the merging portion 47 to the third flow path 46 through the ventilation film 473. Can be prevented.

  Each stepped portion 464 has a flat top surface 465. As a result, as shown in FIG. 7, even if the top surface 465 of the stepped portion 464 contacts the organ 900, the organ 900 can be reliably prevented from being damaged by the top surface 465.

  The constituent materials of the two inner tubes 44a and 45a and the outer tube 46a constituting the nozzle 4 are not particularly limited. For example, polyvinyl chloride, polyethylene, polypropylene, cyclic polyolefin, polystyrene, poly- (4-methylpentene) -1), polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, polyester such as polyethylene terephthalate, polyethylene naphthalate, butadiene-styrene copolymer, polyamide (for example, nylon 6, nylon 6,6, nylon 6)・ Various soft or hard resins such as 10, nylon 12), natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, various rubber materials such as silicone rubber, polyurethane, polyester Polyamide, olefin, various thermoplastic elastomers of styrene such as, stainless steel, aluminum, various metal materials such as copper or copper-based alloy, various kinds of glass, alumina, various ceramics such as silica and the like.

  As shown in FIGS. 1 and 2, an operation member 5 is installed on the base end side of the applicator main body 7. The operation member 5 collectively presses the gaskets 24 of the first syringe 2 and the second syringe 3. Further, in the applicator 1, the operation member 5 is provided with a pressing assist means (hereinafter simply referred to as “auxiliary means”) 6 that assists the pressing operation when the operating member 5 is pressed.

  The operation member 5 has a tubular support part 52 supported by the applicator main body 7, a gasket 53 installed at the tip of the support part 52, and a tubular part arranged on the outer peripheral side via the support part 52. It has the pusher portions 51a and 51b.

  The support 52 is inserted into the operation member connection portion 732 of the applicator main body 7 at the tip side, and can move along the longitudinal direction of the operation member connection portion 732 (connection portion 73). Further, as shown in FIG. 2, the through hole of the support portion 52 functions as a finger contact portion 521 on which the finger 800 is hung when the operation member 5 is pressed. The finger pad 521 is preferably made of an elastic material. Thereby, when the finger 800 is addressed to the finger contact portion 521, the finger contact portion 521 is deformed along the shape of the finger 800, and thus the pressing operation is facilitated.

  A gasket 53 is connected and fixed to the tip of the support portion 52 by, for example, screwing. Further, the gasket 53 has a ring shape, and the lumen portion thereof communicates with the lumen portion of the support portion 52. Such a gasket 53 can move together with the support portion 52, and in this case, the outer peripheral surface of the gasket 53 slides while being in close contact with the inner peripheral surface of the operation member connecting portion 732. Accordingly, the gas G flowing into the connection portion 73 via the tube 302b is prevented from leaking from the operation member connection portion 732, and thus, into the lumen portion of the support portion 52 via the lumen portion of the gasket 53. It can flow in reliably. Therefore, the lumen portion of the gasket 53 and the lumen portion of the support portion 52 function as a gas flow path 54 through which the gas G passes. In addition, as a constituent material of the gasket 53, the elastic material similar to the gasket 24 can be used.

  The pusher 51a is connected and fixed to the gasket 24 of the first syringe 2 by, for example, screwing. Further, the proximal end portion of the pusher portion 51 a is connected to the middle of the support portion 52. The pusher portion 51b is connected and fixed to the gasket 24 of the second syringe 3 by screwing, for example, like the pusher portion 51a. Further, the proximal end portion of the pusher portion 51 b is connected to the middle of the support portion 52.

  When the finger contact part 521 of the support part 52 is pressed, the pusher parts 51a and 51b are moved together with the operation. Thereby, each gasket 24 of the 1st syringe 2 and the 2nd syringe 3 can be collectively moved reliably.

  The pusher portions 51a and 51b are connected to the support portion 52, respectively. As a result, the lumen portions of the pusher portions 51a and 51b communicate with the lumen portion of the support portion 52, that is, the gas flow path 54, respectively. Thereby, as shown in FIG. 2, when the finger 800 is put on the finger contact portion 521 of the support portion 52, the finger contact portion 521 is blocked, and the gas G that has passed through the gas flow path 54 is separated from the pusher portion 51 a and 51b can flow into each lumen. Accordingly, the lumen portions of the pusher portions 51a and 51b become gas flow paths 55 and 56, respectively.

  Each of the pusher portions 51 a and 51 b is formed with a supply port 511 that is configured by a through-hole penetrating the tube wall and opens to the proximal end side space 212. The gas G is supplied to the proximal end space 212 through the supply port 511 (see FIG. 2).

  Further, as shown in FIG. 1, in a state where the finger pad 521 is opened, the gas G that has passed through the gas flow path 54 is preferentially directed toward the finger pad 521, and thus the finger pad 521. Through the atmosphere.

  Although it does not specifically limit as a constituent material of the support part 52 and the pusher parts 51a and 51b, For example, various resin raised with description about the outer cylinder 21 can be used.

Next, the auxiliary means 6 will be described.
The auxiliary means 6 assists the pressing operation when the operating member 5 is pressed. A part of the auxiliary means 6 is constituted by gas flow paths 54 to 56. As described above, the gas G that has passed through the gas flow path 54 branches into the gas flow path 55 and the gas flow path 56 and passes through the respective flow paths. A flow path composed of gas flow paths 54 and 55 (hereinafter referred to as “first gas flow path 57”) and a flow path composed of gas flow paths 54 and 56 (hereinafter referred to as “second gas flow path 58”). ”) Has the same function, and therefore, the first gas channel 57 will be representatively described below.

  As shown in FIG. 2, in a state where the finger resting part 521 is closed with the finger 800, the gas G that has passed through the first gas flow path 57 passes through the supply port 511 and is on the proximal end side of the first syringe 2. It is supplied to the space 212. By the supply of the gas G, the pressure in the base end side space 212 increases (the base end side space 212 is pressurized). Therefore, the pressing force that presses and moves the gasket 24 toward the tip end direction. F1 occurs.

  When using the applicator 1, the operator puts the finger 800 on the finger rest 521 and presses the operation member 5 to move each gasket 24 in the distal direction. At that time, since the pressing force F1 is generated as described above, the pressing operation with respect to the gasket 24 can be easily and reliably performed through the operation member 5 together with the pressing force F2 by the finger 800.

  For example, if the auxiliary means 6 is omitted, the pressing force F1 does not occur. Therefore, when operating the applicator, the operating member 5 can be pressed only with the pressing force F2. In this case, an operator who has a relatively weak gripping force such as a woman generally presses the operation member 5 easily if the viscosity of the first liquid L1 or the second liquid L2 is relatively high. It cannot be operated or a pressing operation becomes impossible at all. However, in the applicator 1, since the pressing force F2 by the auxiliary means 6 is generated, such a problem can be reliably prevented.

  The pressing force F1 is set to be smaller than the sliding resistance when the gasket 24 slides in the outer cylinder 21. Thereby, even when the finger contact part 521 is closed unintentionally, it is possible to reliably prevent the gasket 24 from moving due to the pressing force F1. A method for setting such a magnitude relationship of the force is not particularly limited. For example, a method of appropriately setting the degree of fitting between the gasket 24 and the outer cylinder 21, a lubricating liquid between the gasket 24 and the outer cylinder 21. And a method of appropriately setting the amount and type of the above.

  In addition, as shown in FIG. 1, in a state where the finger contact part 521 is not blocked by the finger 800 and is opened, the gas G is discharged into the atmosphere through the opened finger contact part 521. In this case, the supply of the gas G to each proximal end space 212 of the first syringe 2 and the second syringe 3 is stopped. Thereby, application | coating of the liquid mixture of the 1st liquid L1 and the 2nd liquid L2 is also stopped.

  Thus, in the applicator 1, it can be said that the finger contact part 521 functions as a switching part for switching the supply and stop of the gas G to the proximal-side spaces 212 of the auxiliary means 6. . By providing this switching portion, it is possible to reliably generate the pressing force F1 when it is desired to perform the coating operation, and to reliably prevent the pressing force F1 from occurring when it is desired to stop the coating operation.

  Further, as described above, in the application tool 1 in the application stop state shown in FIG. 1, a part of the gas G flowing into the application tool 1 from the gas cylinder 300b through the tube 302b is discharged from the finger contact unit 521. The Thereby, in the application stop state, even if the nozzle 4 is inserted into the abdominal cavity and only the gas G is ejected from the abdominal cavity, the gas G is discharged, so that the excessive flow of the gas G into the abdominal cavity is caused. Therefore, it is possible to reliably prevent the insufficiency of the abdominal pressure in the abdominal cavity.

  Further, as described above, even if the tip 463 of the nozzle 4 comes into contact with the organ 900, the step 464 prevents the ejection port 424 from being blocked by the organ 900 (see FIG. 7). Thereby, even when the tip 463 of the nozzle 4 contacts the organ 900 in the application state shown in FIG. 2, the first liquid L1, the second liquid L2, and the gas G are each prevented from losing their place. Thus, the pressing force F1 acts reliably, and the first liquid L1 and the second liquid L2 can be reliably pushed out by the gaskets 24, respectively.

  Next, the first syringe 2 filled with the first liquid L1 and the second syringe 3 filled with the second liquid L2 are loaded, and the gas cylinder 300b is ready for use. The application state of the applicator 1 (nozzle 4) in a state of being connected to will be described.

  The first syringe 2 and the second syringe 3 are respectively filled with the first liquid L1 and the second liquid L2 having sufficient liquid amounts to be applied to the affected area. In this state, as shown in FIGS. 1 and 4, the first liquid L1 is not supplied to the first flow path 44, and the second liquid L2 is not supplied to the second flow path 45. Not supplied. Further, when the valve of the gas cylinder 300b is opened, the gas G is supplied into the applicator 1 through the tube 302b. As a result, as shown in FIG. 4, the gas G toward the nozzle 4 flows into the merging portion 47 via the gas permeable membrane 473 that defines the merging portion 47, passes through the merging portion 47, and then is ejected from the jet port 424. Erupts from.

  Then, when the finger 800 is operated to press the finger contact portion 521 of the operation member 5 of the applicator 1 with the pressing force F2 from the state shown in FIG. 1, the first liquid L1 is supplied to the first flow path 44. The second liquid L2 is supplied to the second flow path 45 (see FIGS. 2 and 5). At this time, as described above, the auxiliary means 6 operates, that is, the gas G enters the proximal end side space 212 of each syringe through the first gas passage 57 and the second gas passage 58, respectively. Supplied. Thereby, the pressing force F1 is generated, and the pressing operation on the operation member 5 can be easily performed by the resultant force of the pressing force F1 and the pressing force F2 (see FIG. 2). This state continues until the finger 800 is separated from the finger rest 521.

  Further, when the pressing of the applicator 1 against the operation member 5 is continued, the first liquid L1 and the second liquid L2 flow into the joining portion 47 and are mixed. On the other hand, the gas G continues to flow into the merging portion 47 via the gas permeable membrane 473 as described above. And the liquid mixture spouts with the gas G from the jet nozzle 424 (refer FIG. 5). This mixed liquid is atomized by the gas G ejected at a high speed, and is applied to the affected area.

  Then, after the application of the predetermined amount of the mixed liquid to the affected part is completed, the finger 800 is separated from the finger contact part 521. As a result, the supply of the first liquid L1 to the first flow path 44 is stopped, and the supply of the second liquid L2 to the second flow path 45 is stopped.

  In addition, since the supply of the gas G to the applicator 1 is not stopped, a part of the gas G continues to flow into the junction 47. Thereby, in the confluence | merging part 47, a liquid mixture is extruded from the jet nozzle 424 by the gas G which flowed in through the ventilation film 473 (refer FIG. 6). As a result, the tip P1 of the first liquid L1 is positioned near the tip 441 of the first flow path 44, and the tip P2 of the second liquid L2 is positioned near the tip 451 of the second flow path 45. . With such a configuration, the mixed liquid is prevented from remaining in the junction portion 47, particularly in the vicinity of the ejection port 424, and further, the mixed liquid is prevented from gelling. This reliably prevents clogging at the jet nozzle 424. Then, the applicator 1 in a state where the clogging does not occur can be used again for application to the affected area.

Second Embodiment
FIG. 8 is a longitudinal sectional view showing an operation member of the applicator (second embodiment).

  Hereinafter, the second embodiment of the liquid supply tool of the present invention will be described with reference to this figure, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

  This embodiment is the same as the first embodiment except that the degree of contact of the fingertip with the operation member is different.

  As shown in FIG. 8, in the applicator 1, when the finger 800 is applied to the finger contact portion 521 of the operation member 5, the finger 800 can be applied to the extent that the finger contact portion 521 is not completely blocked. . As a result, a gap 522 is formed between the finger contact portion 521 and the finger 800. Since the gas G leaks through the gap 522, the supply amount of the gas G to the proximal end side space 212 of the first syringe 2 and the second syringe 3 can be reduced accordingly. Thereby, the magnitude of the pressing force F1 is adjusted. For example, when it is desired to suppress the degree of the auxiliary action by the auxiliary means 6 when performing the application operation, as shown in FIG. 8, if the finger 800 is applied to such an extent that the finger contact part 521 is not completely blocked, the suppression is suppressed. Can be performed reliably.

<Third Embodiment>
FIG. 9 is a partial longitudinal sectional view showing a third embodiment of the applicator.

  Hereinafter, the third embodiment of the liquid supply device of the present invention will be described with reference to this figure, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

  This embodiment is the same as the first embodiment except that the configuration of the pressing assist means is different.

  In the applicator 1A shown in FIG. 9, when the size of the outer cylinder 21 of the first syringe 2A is compared with the size of the outer cylinder 21 of the second syringe 3, the outer cylinder 21 of the second syringe 3 is better. It is getting bigger.

  Further, in the applicator 1A, a switching valve 59 is installed in the middle of the gas flow path 55 toward the first syringe 2A. The switching valve 59 switches the supply and stop of the gas G to the proximal end side space 212 of the first syringe 2A, and is constituted by, for example, a three-way cock. The state shown in FIG. 9 is a state in which the switching valve 59 can stop the supply of the gas G. And if application | coating operation is performed in this state, the pressing force F1 will not arise in the 1st syringe 2A among the 1st syringe 2A and the 2nd syringe 3, but the pressing force F1 will be applied to the 2nd syringe 3. That is, the auxiliary means 6 acts only on the second syringe 3.

  When performing the coating operation, the first syringe 2A is smaller than the second syringe 3, so that the action of the auxiliary means 6 on the first syringe 2A can be omitted, but the second syringe having a large size 3 can be easily applied when the auxiliary means 6 acts.

  In addition, unlike the state shown in FIG. 9, when the switching valve 59 is rotated 90 degrees counterclockwise in the drawing so that the gas G can be supplied also to the first syringe 2A, the first valve A pressing force F1 is generated in both the syringe 2A and the second syringe 3, that is, the auxiliary unit 6 acts on both.

  As described above, in the applicator 1A, depending on the state of the switching valve 59, whether the auxiliary means 6 operates for one of the first syringe 2A and the second syringe 3 or both. Can be selected.

  In the present embodiment, the applicator 1A is configured such that the auxiliary means 6 always acts on the larger syringe (second syringe 3). The applicator 1A is not limited to such a configuration. For example, when the viscosity of one of the first liquid L1 and the second liquid L2 is higher than the viscosity of the other liquid, The auxiliary means 6 may always be configured to act on a syringe filled with a high liquid.

<Fourth embodiment>
FIG. 10 is a longitudinal sectional view showing a fourth embodiment of the applicator.

  Hereinafter, the fourth embodiment of the liquid supply device of the present invention will be described with reference to this drawing, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

  This embodiment is the same as the first embodiment except that the configuration of the pressing assist means is different.

  In the applicator 1 </ b> B shown in FIG. 10, the auxiliary means 6 is a switching mechanism (switching unit) 61 that switches between supplying and stopping the gas G to the proximal end side spaces 212 of the first syringe 2 and the second syringe 3. It has. The switching mechanism 61 includes a finger contact member 62 inserted into the support portion 52 of the operation member 5 from the proximal end side, and a biasing member 63 that biases the finger contact member 62 toward the proximal end side. ing.

  The finger contact member 62 is formed of a cylindrical member whose base end side is closed, and flange portions 621 and 622 each having an enlarged outer diameter are formed at both ends thereof. As shown in FIG. 10A, the flange portion 621 contacts the reduced diameter portion 523 formed at the proximal end portion of the support portion 52 of the operation member 5, and the finger contact member 62 moves in the proximal direction. This is the part that regulates the limits. As shown in FIG. 10B, the flange portion 622 is a portion to which the finger 800 is applied when the finger contact member 62 is pressed with the finger 800. Note that the reduced diameter portion 523 of the support portion 52 of the operation member 5 has two exhaust ports 524 and 525 each having a through hole penetrating the portion at a base end side of the gas flow paths 55 and 56. Is formed.

  Further, two through holes 623 and 624 that penetrate the wall portion are formed in the middle of the finger contact member 62. The through holes 623 and 624 are arranged symmetrically with respect to the center axis of the finger contact member 62. In the state where the coating operation shown in FIG. 10A is stopped, the through hole 623 opens toward the exhaust port 524, and the through hole 624 opens toward the exhaust port 525. Thereby, the gas flow path 54 communicates with each of the exhaust ports 524 and 525 via the finger contact member 62, and can discharge the gas G from each of the exhaust ports 524 and 525.

  In the state where the application operation shown in FIG. 10B is performed, when the finger contact member 62 is pressed with the finger 800, the through hole 623 opens toward the gas flow path 55 toward the first syringe 2. The through-hole 624 opens toward the gas flow path 56 toward the second syringe 3. Thereby, the gas flow path 54 communicates with each of the gas flow paths 55 and 56 via the finger contact member 62, and can supply the gas G to the first syringe 2 and the second syringe 3, respectively. Therefore, the pressing force F1 is obtained.

  The biasing member 63 is configured by a coil spring. In the urging member 63, the finger contact member 62 is inserted in a contracted state, the distal end 631 contacts the proximal end surface of the support portion 52 of the operation member 5, and the proximal end 632 is the distal end of the flange portion 622 of the finger contact member 62. It is in contact with the surface. Thereby, the finger contact member 62 can be reliably urged toward the proximal direction. Further, the finger contact member 62 can be pressed against the urging force of the urging member 63 (the state shown in FIG. 10B), and when the operation is released, the finger contact is performed by the urging force of the urging member 63. The member 62 returns (state shown in FIG. 10A).

  With the switching mechanism 61 having such a configuration, the operation timing of the auxiliary means 6 can be reliably controlled.

  In the state shown in FIG. 10A, the gas G discharged from the exhaust ports 524 and 525 is discharged toward the side. Thereby, it is prevented that the discharged gas G is blown toward the operator located on the base end side of the applicator 1B.

<Fifth Embodiment>
FIG. 11 to FIG. 13 are partial vertical cross-sectional views (drawing steps in order) showing an embodiment when the liquid supply tool of the present invention is applied to a syringe.

  Hereinafter, the fifth embodiment of the liquid supply tool of the present invention will be described with reference to these drawings, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

  In the first to fourth embodiments, the case where the liquid supply tool of the present invention is applied to an applicator has been described. However, in the present embodiment, the liquid supply tool of the present invention is applied to a syringe. Will be described.

  The syringe 10 shown in FIGS. 11 to 13 is used when sucking a liquid L3 such as a drug solution and administering the sucked liquid. The syringe 10 pushes the gasket 24 toward the distal end when operating the first syringe 2 as a syringe, the puncture needle 8 attached to the mouth portion 22 of the first syringe 2, and the operation member 5D. Auxiliary means 6D. In the syringe 10 (first syringe 2), an operation member 5D as a pusher is connected to the gasket 24, and the gasket 24 can be moved by operating the operation member 5D. In the initial state shown in FIG. 11, the syringe 10 is in an empty state. Then, by pulling the operating member 5D in the proximal direction from the state shown in FIG. 11, the liquid L3 can be sucked into the distal end space 211 of the first syringe 2 (see FIG. 12). Furthermore, the sucked liquid L3 can be discharged by pressing the operating member 5D in the distal direction from the state shown in FIG. 12 (see FIG. 13).

  The puncture needle 8 is composed of a needle body 81 having a sharp needle tip 811 at the tip and a hub 82 installed at the proximal end portion of the needle body 81. The needle body 81 is a hollow needle and can puncture a rubber stopper (not shown) at the mouth of the storage container 400 in which the liquid L3 is stored (see FIG. 11). The hub 82 is attached to the mouth portion 22 of the first syringe 2. The hub 82 has a cylindrical shape and can be fitted into the mouth portion 22. Thereby, the puncture needle 8 is attached to the mouth portion 22 of the first syringe 2, and the inside of the needle body 81 and the distal end side space 211 communicate with each other through the mouth portion 22. In this state, the liquid L3 in the storage container 400 can be sucked into the distal end side space 211 of the first syringe 2 by pulling the operating member 5D in the proximal direction (see FIGS. 11 and 12). ).

  The operation member 5D is formed of a tubular body. As shown in FIG. 13, the lumen of the operation member 5D functions as a gas flow path 54 through which the gas G passes. Further, the operation member 5 </ b> D is formed with a supply port 511 that is configured by a through-hole penetrating the tube wall and opens to the proximal end side space 212. The gas G that has passed through the gas flow path 54 is supplied to the proximal end space 212 through the supply port 511.

  Further, a switching mechanism 61 of the auxiliary means 6D is disposed at the base end portion of the operation member 5D. The switching mechanism 61 switches the supply and stop of the gas G to the proximal end space 212 of the first syringe 2. The switching mechanism 61 includes a finger contact member 62 inserted into the operation member 5D from the proximal end side, and a biasing member 63 that biases the finger contact member 62 toward the proximal end side.

  The finger contact member 62 is formed of a cylindrical member whose base end side is closed, and flange portions 621 and 622 each having an enlarged outer diameter are formed at both ends thereof. As shown in FIGS. 11 and 12, the flange portion 621 contacts the reduced diameter portion 512 formed at the proximal end portion of the operation member 5 </ b> D, and the finger contact member 62 moves in the proximal direction with respect to the operation member 5 </ b> D. This is the part that regulates the limits. As shown in FIG. 13, the flange portion 622 is a portion to which the finger 800 is applied when the finger contact member 62 is pressed with the finger 800.

A through-hole 625 that penetrates the wall portion is formed in the middle of the finger contact member 62.
Further, the tube 302b is connected to the reduced diameter portion 512 of the operation member 5D. As shown in FIG. 13, when the finger contact member 62 is pressed through the tube 302b, the gas G can flow into the gas flow path 54 from the gas cylinder 300b. Further, the reduced diameter portion 512 of the operation member 5D is formed with an exhaust port 513 configured with a through hole penetrating the portion at a base end side with respect to a portion to which the tube 302b is connected. In addition, it is preferable that the exhaust port 513 is provided with a filter member 11 having a bacteria-impermeable property.

  In the suction operation state shown in FIG. 11, the through hole 625 opens toward the exhaust port 513 and the through hole 624 opens toward the exhaust port 525. Thereby, the gas G1 existing in the proximal end side space 212 of the first syringe 2 in the initial state can be discharged from the exhaust port 513. Therefore, the pulling operation of the operation member 5D can be easily and reliably performed.

  Further, even when the operation shown in FIG. 12 is stopped, the through hole 624 opens toward the exhaust port 525. Since the filter member 11 is installed at the exhaust port 513, air is prevented from flowing through the exhaust port 513, so that the inside of the proximal end side space 212 can be maintained in a sterile state.

  In the state where the application operation shown in FIG. 13 is performed, when the finger contact member 62 is pressed with the finger 800, the through hole 625 opens toward the tube 302b. Thereby, the gas flow path 54 communicates with the tube 302b via the finger contact member 62, and can supply the gas G into the proximal end side space 212, thereby obtaining the pressing force F1. Then, the pressing force F1 and the pressing force F2 by the finger 800 are combined, so that the pressing operation on the operation member 5D can be easily and reliably performed.

  The biasing member 63 is configured by a coil spring. In the urging member 63, the finger contact member 62 is inserted in the contracted state, the distal end 631 contacts the proximal end surface of the operation member 5D, and the proximal end 632 contacts the distal end surface of the flange portion 622 of the finger contacting member 62. ing. Thereby, the finger contact member 62 can be reliably urged toward the proximal direction. Also, the finger contact member 62 can be pressed against the urging force of the urging member 63 (state shown in FIG. 13), and when the operation is released, the finger contact member 62 is moved by the urging force of the urging member 63. Return (state shown in FIG. 12).

  With the switching mechanism 61 having such a configuration, the operation timing of the auxiliary means 6D can be reliably controlled.

  As mentioned above, although the liquid supply tool of this invention was demonstrated about embodiment of illustration, this invention is not limited to this, Each part which comprises a liquid supply tool is arbitrary which can exhibit the same function. It can be replaced with the configuration of Moreover, arbitrary components may be added.

  Moreover, the liquid supply tool of the present invention may be a combination of any two or more configurations (features) of the above embodiments.

  Moreover, although the applicator to which the liquid supply tool of the present invention is applied is used by loading two syringes in this embodiment, the present invention is not limited to this. For example, one or three or more It may be used by loading a syringe.

  The gas used for the auxiliary means is also used as the gas used for ejecting the liquid, that is, the gas supplied from one gas supply means, but is not limited to this, and the gas supply means It may be a gas supplied from another gas supply means. As a result, as the gas used for the auxiliary means, it is possible to use a sterile gas or a non-sterile gas.

1, 1A, 1B Applicator 10 Syringe 2, 2A First syringe (liquid supply means)
21 outer cylinder (syringe outer cylinder)
211 Front end side space (Liquid storage space)
212 Base side space 22 Mouth (reduced diameter part)
23 Flange 24 Gasket 25 Stopper 27 Seal member 3 Second syringe (liquid supply means)
4 Nozzle 41 Liquid Channel 42 Nozzle Head 424 Jet Port 43 Nozzle Body 44 First Channel 44a Inner Tube (Inner Tube)
441 Tip 45 Second flow path 45a Inner tube (inner tube)
451 tip 46 third channel (gas channel)
46a Outer tube (outer tube)
461 Tip inner periphery 463 Tip 464 Stepped portion 465 Top surface 466 Bottom surface 467 Groove 47 Merge portion 47a Tube (Merge portion forming tube)
471 Tip portion 472 Base end portion 473 Venting membrane 5, 5D Operation member 51 a, 51 b Pusher portion 511 Supply port 512 Reduced diameter portion 513 Exhaust port 52 Support unit 521 Finger contact portion 522 Gap 523 Reduced diameter portion 524, 525 Exhaust port 53 Gasket 54, 55, 56 Gas flow path 57 First gas flow path 58 Second gas flow path 59 Switching valve 6, 6D Press auxiliary means (auxiliary means)
61 Switching mechanism (switching section)
62 Finger contact member 621, 622 Flange part 623, 624, 625 Through hole 63 Biasing member 631 Tip 632 Base end 7 Application tool body 71 Syringe holding part 711 Fitting part 73 Connection part 731 Nozzle connection part 732 Operation member connection part 8 Puncture needle 81 Needle body 811 Needle tip 82 Hub 11 Filter member 300b Gas cylinder (gas supply means)
302b tube 400 storage container 800 finger 900 organ F1, F2 pressing force G, G1 gas (sterile gas)
L1 1st liquid L2 2nd liquid L3 Liquid P1, P2 tip

Claims (10)

A syringe outer cylinder having a mouth projecting from the tip; a gasket that is inserted into the syringe outer cylinder and moves along a longitudinal direction thereof; and an operation member that moves the gasket. A liquid supply device including a first syringe and a second syringe that operates a member to discharge a liquid filled in a distal end side space surrounded by the syringe outer cylinder and the gasket from the mouth. And
The syringe outer cylinder is hermetically sealed at its proximal end opening,
The second syringe has a smaller force required to move the gasket when discharging the liquid than the first syringe.
When operating the operation member, gas is supplied into the proximal side space closer to the proximal side than the gasket of the syringe outer cylinder of the first syringe and the second syringe, and the proximal side A press assisting means capable of pressing the gaskets of the first syringe and the second syringe toward the distal direction by pressurizing the space;
The liquid supply unit characterized in that the pressing assisting unit can select whether to operate with respect to the first syringe or to both the first syringe and the second syringe. Ingredients. An applicator body that holds the first syringe and the second syringe;
The liquid supply device according to claim 1, further comprising: a nozzle that ejects the liquid ejected from the mouth portion and applies it to a target site by pressing the operation member toward a distal direction. . The nozzle is connected to a gas supply means for supplying a gas;
The pressing assist means includes a first gas flow path for supplying a part of the gas supplied from the gas supply means into the proximal end side space of the first syringe, and the second syringe. A second gas flow path for supplying the gas into the proximal end space, and the gas supply to the proximal end space of the second syringe and its stop, provided in the middle of the second gas flow path. The liquid supply tool according to claim 2, further comprising a switching unit for switching.   The liquid supply tool according to claim 3, wherein the operation member is formed of a tube, and a lumen portion of the tube functions as the first gas channel and the second gas channel. The said pressing assistance means is a through-hole formed in the said tubular body, Comprising: It is closed at the time of supply of the said gas, and has a through-hole opened at the time of the stop of the supply. Liquid supply tool.   The liquid supply tool according to claim 5, wherein the gas is discharged into the atmosphere through the through hole when the through hole is open.   The liquid supply tool according to claim 3, wherein the switching unit is configured to be capable of adjusting a supply amount of the gas.   The liquid material supply according to any one of claims 1 to 7, wherein a pressing force when the pressing auxiliary means presses the gasket is smaller than a sliding resistance when the gasket slides in the syringe outer cylinder. Ingredients.   The liquid supply tool according to any one of claims 1 to 8, wherein a viscosity of the liquid filled in the first syringe is higher than a viscosity of the liquid filled in the second syringe.   10. The liquid supply tool according to claim 1, wherein an inner diameter of the syringe outer cylinder of the first syringe is larger than an inner diameter of the syringe outer cylinder of the second syringe.

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