JP4756218B2 - 光伝搬モードを用いる物質内の光不均質性およびその他特性の測定 - Google Patents
光伝搬モードを用いる物質内の光不均質性およびその他特性の測定Info
- Publication number
- JP4756218B2 JP4756218B2 JP2006515173A JP2006515173A JP4756218B2 JP 4756218 B2 JP4756218 B2 JP 4756218B2 JP 2006515173 A JP2006515173 A JP 2006515173A JP 2006515173 A JP2006515173 A JP 2006515173A JP 4756218 B2 JP4756218 B2 JP 4756218B2
- Authority
- JP
- Japan
- Prior art keywords
- sample
- light
- optical
- waveguide
- propagation mode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003287 optical effect Effects 0.000 title claims description 316
- 238000005259 measurement Methods 0.000 title claims description 49
- 239000000463 material Substances 0.000 title claims description 22
- 239000000523 sample Substances 0.000 claims description 398
- 230000010287 polarization Effects 0.000 claims description 92
- 238000000034 method Methods 0.000 claims description 67
- 230000005855 radiation Effects 0.000 claims description 55
- 238000001514 detection method Methods 0.000 claims description 52
- 230000003595 spectral effect Effects 0.000 claims description 46
- 239000000835 fiber Substances 0.000 claims description 31
- 230000036961 partial effect Effects 0.000 claims description 23
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 19
- 239000008103 glucose Substances 0.000 claims description 19
- 230000008859 change Effects 0.000 claims description 15
- 230000009977 dual effect Effects 0.000 claims description 15
- 230000004044 response Effects 0.000 claims description 14
- 230000008569 process Effects 0.000 claims description 7
- 239000000284 extract Substances 0.000 claims description 5
- 230000003993 interaction Effects 0.000 claims description 5
- 230000002500 effect on skin Effects 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 239000004973 liquid crystal related substance Substances 0.000 claims description 2
- 230000000644 propagated effect Effects 0.000 claims description 2
- 230000003111 delayed effect Effects 0.000 claims 4
- 238000003491 array Methods 0.000 claims 1
- 238000013461 design Methods 0.000 description 34
- 238000010521 absorption reaction Methods 0.000 description 22
- 230000006870 function Effects 0.000 description 15
- 239000013307 optical fiber Substances 0.000 description 11
- 239000000126 substance Substances 0.000 description 11
- 238000002281 optical coherence-domain reflectometry Methods 0.000 description 10
- 230000008901 benefit Effects 0.000 description 9
- 238000001228 spectrum Methods 0.000 description 9
- 210000004369 blood Anatomy 0.000 description 8
- 239000008280 blood Substances 0.000 description 8
- 210000002615 epidermis Anatomy 0.000 description 8
- 210000003491 skin Anatomy 0.000 description 8
- 210000001519 tissue Anatomy 0.000 description 7
- 230000001419 dependent effect Effects 0.000 description 6
- 210000004207 dermis Anatomy 0.000 description 6
- 238000001615 p wave Methods 0.000 description 6
- 230000001902 propagating effect Effects 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 4
- 238000009826 distribution Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- 238000012544 monitoring process Methods 0.000 description 4
- 230000000737 periodic effect Effects 0.000 description 4
- 230000010363 phase shift Effects 0.000 description 4
- 230000002441 reversible effect Effects 0.000 description 4
- 238000012512 characterization method Methods 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 230000005684 electric field Effects 0.000 description 3
- 238000011835 investigation Methods 0.000 description 3
- 230000008520 organization Effects 0.000 description 3
- 230000010355 oscillation Effects 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 238000000862 absorption spectrum Methods 0.000 description 2
- 230000001427 coherent effect Effects 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 210000003722 extracellular fluid Anatomy 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012014 optical coherence tomography Methods 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- 241000282461 Canis lupus Species 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000006117 anti-reflective coating Substances 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000005562 fading Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- GQYHUHYESMUTHG-UHFFFAOYSA-N lithium niobate Chemical compound [Li+].[O-][Nb](=O)=O GQYHUHYESMUTHG-UHFFFAOYSA-N 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 238000002310 reflectometry Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N titanium dioxide Inorganic materials O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14558—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters by polarisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/02001—Interferometers characterised by controlling or generating intrinsic radiation properties
- G01B9/0201—Interferometers characterised by controlling or generating intrinsic radiation properties using temporal phase variation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/02041—Interferometers characterised by particular imaging or detection techniques
- G01B9/02044—Imaging in the frequency domain, e.g. by using a spectrometer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/02055—Reduction or prevention of errors; Testing; Calibration
- G01B9/02056—Passive reduction of errors
- G01B9/02057—Passive reduction of errors by using common path configuration, i.e. reference and object path almost entirely overlapping
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/0209—Low-coherence interferometers
- G01B9/02091—Tomographic interferometers, e.g. based on optical coherence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/021—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using plane or convex mirrors, parallel phase plates, or particular reflectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0224—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using polarising or depolarising elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/42—Absorption spectrometry; Double beam spectrometry; Flicker spectrometry; Reflection spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/21—Polarisation-affecting properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
- G01N21/474—Details of optical heads therefor, e.g. using optical fibres
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/06—Means for illuminating specimens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
- A61B2562/0242—Special features of optical sensors or probes classified in A61B5/00 for varying or adjusting the optical path length in the tissue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
- G01B2290/35—Mechanical variable delay line
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
- G01B2290/40—Non-mechanical variable delay line
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
- G01B2290/45—Multiple detectors for detecting interferometer signals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B2290/00—Aspects of interferometers not specifically covered by any group under G01B9/02
- G01B2290/70—Using polarization in the interferometer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4704—Angular selective
- G01N2021/4709—Backscatter
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4792—Polarisation of scatter light
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Optics & Photonics (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Optical Integrated Circuits (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47567303P | 2003-06-04 | 2003-06-04 | |
| US60/475,673 | 2003-06-04 | ||
| US51476803P | 2003-10-27 | 2003-10-27 | |
| US60/514,768 | 2003-10-27 | ||
| US52693503P | 2003-12-04 | 2003-12-04 | |
| US60/526,935 | 2003-12-04 | ||
| US56158804P | 2004-04-12 | 2004-04-12 | |
| US60/561,588 | 2004-04-12 | ||
| PCT/US2004/017649 WO2005001522A2 (en) | 2003-06-04 | 2004-06-04 | Measurements of optical inhomogeneity and other properties in substances using propagation modes of light |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006526790A JP2006526790A (ja) | 2006-11-24 |
| JP2006526790A5 JP2006526790A5 (https=) | 2007-09-20 |
| JP4756218B2 true JP4756218B2 (ja) | 2011-08-24 |
Family
ID=37544710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006515173A Expired - Lifetime JP4756218B2 (ja) | 2003-06-04 | 2004-06-04 | 光伝搬モードを用いる物質内の光不均質性およびその他特性の測定 |
Country Status (4)
| Country | Link |
|---|---|
| US (11) | US6943881B2 (https=) |
| JP (1) | JP4756218B2 (https=) |
| CA (1) | CA2528417C (https=) |
| WO (1) | WO2005001522A2 (https=) |
Families Citing this family (297)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60141090D1 (de) | 2000-10-30 | 2010-03-04 | Gen Hospital Corp | Optische systeme zur gewebeanalyse |
| US9295391B1 (en) | 2000-11-10 | 2016-03-29 | The General Hospital Corporation | Spectrally encoded miniature endoscopic imaging probe |
| WO2002088705A2 (en) | 2001-05-01 | 2002-11-07 | The General Hospital Corporation | Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties |
| US7355716B2 (en) | 2002-01-24 | 2008-04-08 | The General Hospital Corporation | Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands |
| US7259906B1 (en) | 2002-09-03 | 2007-08-21 | Cheetah Omni, Llc | System and method for voice control of medical devices |
| US7289837B2 (en) | 2002-10-01 | 2007-10-30 | Nellcor Puritan Bennett Incorpoated | Forehead sensor placement |
| US8054468B2 (en) | 2003-01-24 | 2011-11-08 | The General Hospital Corporation | Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands |
| CA2519937C (en) | 2003-03-31 | 2012-11-20 | Guillermo J. Tearney | Speckle reduction in optical coherence tomography by path length encoded angular compounding |
| US9134231B2 (en) * | 2003-06-04 | 2015-09-15 | Tomophase, Inc. | Optical measurements of properties in substances using propagation modes of light |
| US6943881B2 (en) * | 2003-06-04 | 2005-09-13 | Tomophase Corporation | Measurements of optical inhomogeneity and other properties in substances using propagation modes of light |
| EP2280260B1 (en) | 2003-06-06 | 2017-03-08 | The General Hospital Corporation | Process and apparatus for a wavelength tuned light source |
| US7047056B2 (en) | 2003-06-25 | 2006-05-16 | Nellcor Puritan Bennett Incorporated | Hat-based oximeter sensor |
| US8412297B2 (en) | 2003-10-01 | 2013-04-02 | Covidien Lp | Forehead sensor placement |
| CA2541297C (en) | 2003-10-03 | 2013-12-10 | Academisch Medisch Centrum | System and method for imaging the reflectance of a substrate |
| JP5567246B2 (ja) | 2003-10-27 | 2014-08-06 | ザ ジェネラル ホスピタル コーポレイション | 周波数ドメイン干渉測定を利用して光学撮像を実行する方法および装置 |
| JP5214883B2 (ja) | 2003-11-28 | 2013-06-19 | ザ ジェネラル ホスピタル コーポレイション | 三次元分光的符号化撮像のための方法と装置 |
| US7230684B2 (en) * | 2004-03-10 | 2007-06-12 | Raytheon Company | Method and apparatus for range finding with a single aperture |
| WO2005117534A2 (en) | 2004-05-29 | 2005-12-15 | The General Hospital Corporation | Process, system and software arrangement for a chromatic dispersion compensation using reflective layers in optical coherence tomography (oct) imaging |
| AU2005270037B2 (en) | 2004-07-02 | 2012-02-09 | The General Hospital Corporation | Endoscopic imaging probe comprising dual clad fibre |
| EP1782020B1 (en) | 2004-08-06 | 2012-10-03 | The General Hospital Corporation | Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography |
| WO2006024015A1 (en) | 2004-08-24 | 2006-03-02 | The General Hospital Corporation | Method and apparatus for imaging of vessel segments |
| WO2006024014A2 (en) | 2004-08-24 | 2006-03-02 | The General Hospital Corporation | Process, system and software arrangement for measuring a mechanical strain and elastic properties of a sample |
| JP5215664B2 (ja) | 2004-09-10 | 2013-06-19 | ザ ジェネラル ホスピタル コーポレイション | 光学コヒーレンス撮像のシステムおよび方法 |
| JP4997112B2 (ja) | 2004-09-29 | 2012-08-08 | ザ ジェネラル ホスピタル コーポレイション | 少なくとも1つの電磁放射を伝送させるための装置およびその製造方法 |
| US8498681B2 (en) * | 2004-10-05 | 2013-07-30 | Tomophase Corporation | Cross-sectional mapping of spectral absorbance features |
| US7970458B2 (en) * | 2004-10-12 | 2011-06-28 | Tomophase Corporation | Integrated disease diagnosis and treatment system |
| JP5623692B2 (ja) * | 2004-11-02 | 2014-11-12 | ザ ジェネラル ホスピタル コーポレイション | 試料の画像形成のための光ファイバ回転装置、光学システム及び方法 |
| EP2278265A3 (en) | 2004-11-24 | 2011-06-29 | The General Hospital Corporation | Common-Path Interferometer for Endoscopic OCT |
| US8922781B2 (en) | 2004-11-29 | 2014-12-30 | The General Hospital Corporation | Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample |
| US9131861B2 (en) * | 2004-11-30 | 2015-09-15 | Academisch Medisch Centrum | Pulsed lighting imaging systems and methods |
| US7230710B2 (en) * | 2004-12-21 | 2007-06-12 | Axsun Technologies, Inc. | Polarization controlling fiber probe for semiconductor source spectroscopy system |
| US20060153739A1 (en) * | 2005-01-13 | 2006-07-13 | Hilderbrand Glen D | Methods and systems for testing materials |
| US7199870B2 (en) * | 2005-02-10 | 2007-04-03 | Picosolve Inc. | Polarization independent optical sampling arrangement |
| EP1869398B1 (en) * | 2005-03-17 | 2012-08-22 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and method for frequency-domain optical coherence tomography |
| US7369953B2 (en) | 2005-03-17 | 2008-05-06 | The Board Of Trustees Of The Leland Stanford Junior University | Femtosecond spectroscopy using minimum phase functions |
| US20060215076A1 (en) * | 2005-03-22 | 2006-09-28 | Karim John H | Selective light transmitting and receiving system and method |
| EP1866616B1 (en) | 2005-04-05 | 2013-01-16 | The Board Of Trustees Of The Leland Stanford Junior University | Optical image processing using minimum phase functions |
| KR20080013919A (ko) * | 2005-04-22 | 2008-02-13 | 더 제너럴 하스피탈 코포레이션 | 스펙트럼 도메인 편광 민감형 광간섭 단층촬영을 제공할 수있는 장치, 시스템 및 방법 |
| EP2085929A1 (en) | 2005-04-28 | 2009-08-05 | The General Hospital Corporation | Evaluating optical coherence tomography information for an anatomical structure |
| US7505150B2 (en) * | 2005-05-13 | 2009-03-17 | Laytec Gmbh | Device and method for the measurement of the curvature of a surface |
| WO2006130797A2 (en) | 2005-05-31 | 2006-12-07 | The General Hospital Corporation | Spectral encoding heterodyne interferometry techniques for imaging |
| EP1889037A2 (en) | 2005-06-01 | 2008-02-20 | The General Hospital Corporation | Apparatus, method and system for performing phase-resolved optical frequency domain imaging |
| US7783337B2 (en) | 2005-06-06 | 2010-08-24 | Board Of Regents, The University Of Texas System | OCT using spectrally resolved bandwidth |
| US7428053B2 (en) * | 2005-07-08 | 2008-09-23 | Imalux Corporation | Common path frequency domain optical coherence reflectometry/tomography device |
| ATE484727T1 (de) | 2005-08-09 | 2010-10-15 | Gen Hospital Corp | Gerät und verfahren zur durchführung von polarisationsbasierter quadraturdemodulation bei optischer kohärenztomographie |
| AU2006299659A1 (en) | 2005-09-29 | 2007-04-12 | General Hospital Corporation | Method and apparatus for method for viewing and analyzing of one or more biological samples with progressively increasing resolutions |
| US7450241B2 (en) * | 2005-09-30 | 2008-11-11 | Infraredx, Inc. | Detecting vulnerable plaque |
| US7831298B1 (en) | 2005-10-04 | 2010-11-09 | Tomophase Corporation | Mapping physiological functions of tissues in lungs and other organs |
| US7889348B2 (en) | 2005-10-14 | 2011-02-15 | The General Hospital Corporation | Arrangements and methods for facilitating photoluminescence imaging |
| US7728985B2 (en) * | 2005-11-14 | 2010-06-01 | Imalux Corporation | Polarization-sensitive common path optical coherence reflectometry/tomography device |
| US20070109554A1 (en) * | 2005-11-14 | 2007-05-17 | Feldchtein Felix I | Polarization sensitive optical coherence device for obtaining birefringence information |
| JP2007178409A (ja) * | 2005-12-28 | 2007-07-12 | Topcon Corp | 光画像計測装置 |
| EP1971848B1 (en) | 2006-01-10 | 2019-12-04 | The General Hospital Corporation | Systems and methods for generating data based on one or more spectrally-encoded endoscopy techniques |
| US8145018B2 (en) | 2006-01-19 | 2012-03-27 | The General Hospital Corporation | Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements |
| ES2847854T3 (es) | 2006-01-19 | 2021-08-04 | Massachusetts Gen Hospital | Catéter de globo de obtención de imágenes |
| EP1983921B1 (en) | 2006-02-01 | 2016-05-25 | The General Hospital Corporation | Systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures |
| JP2009537024A (ja) | 2006-02-01 | 2009-10-22 | ザ ジェネラル ホスピタル コーポレイション | 少なくとも一つのファイバの少なくとも二つの部位の少なくとも一つを制御する装置 |
| US7538859B2 (en) | 2006-02-01 | 2009-05-26 | The General Hospital Corporation | Methods and systems for monitoring and obtaining information of at least one portion of a sample using conformal laser therapy procedures, and providing electromagnetic radiation thereto |
| EP3143926B1 (en) | 2006-02-08 | 2020-07-01 | The General Hospital Corporation | Methods, arrangements and systems for obtaining information associated with an anatomical sample using optical microscopy |
| JP5044126B2 (ja) | 2006-02-23 | 2012-10-10 | オリンパス株式会社 | 内視鏡観察装置および画像形成を行う内視鏡の作動方法 |
| US7982879B2 (en) | 2006-02-24 | 2011-07-19 | The General Hospital Corporation | Methods and systems for performing angle-resolved fourier-domain optical coherence tomography |
| US7742173B2 (en) | 2006-04-05 | 2010-06-22 | The General Hospital Corporation | Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample |
| JP4925278B2 (ja) * | 2006-04-25 | 2012-04-25 | パナソニック株式会社 | 光学的生体情報測定方法及びその装置 |
| EP3150110B1 (en) | 2006-05-10 | 2020-09-02 | The General Hospital Corporation | Processes, arrangements and systems for providing frequency domain imaging of a sample |
| US7782464B2 (en) | 2006-05-12 | 2010-08-24 | The General Hospital Corporation | Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images |
| US7869054B2 (en) * | 2006-05-26 | 2011-01-11 | Medeikon Corporation | Polarization insensitive multiple probe |
| WO2008018001A2 (en) * | 2006-08-09 | 2008-02-14 | Koninklijke Philips Electronics N.V. | Light-emitting apparatus, particularly for flow measurements |
| US9867530B2 (en) | 2006-08-14 | 2018-01-16 | Volcano Corporation | Telescopic side port catheter device with imaging system and method for accessing side branch occlusions |
| EP2054712B1 (en) | 2006-08-25 | 2015-10-07 | The General Hospital Corporation | Apparatus and methods for enhancing optical coherence tomography imaging using volumetric filtering techniques |
| US20100087739A1 (en) * | 2006-09-26 | 2010-04-08 | Koninklijke Philips Electronics N.V. | Apparatus for optical body analysis |
| US8838213B2 (en) | 2006-10-19 | 2014-09-16 | The General Hospital Corporation | Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample, and effecting such portion(s) |
| JP2008139170A (ja) * | 2006-12-01 | 2008-06-19 | Fuji Heavy Ind Ltd | 衝撃探知システム |
| JP5052116B2 (ja) * | 2006-12-19 | 2012-10-17 | 富士フイルム株式会社 | 光断層画像化装置 |
| EP2104968A1 (en) | 2007-01-19 | 2009-09-30 | The General Hospital Corporation | Rotating disk reflection for fast wavelength scanning of dispersed broadband light |
| WO2008089406A2 (en) | 2007-01-19 | 2008-07-24 | The General Hospital Corporation | Apparatus and method for simultaneous inspection at different depths based on the principle of frequency domain optical coherence tomography |
| WO2008090599A1 (ja) * | 2007-01-22 | 2008-07-31 | School Juridical Person Kitasato Institute | オプティカル・コヒーレンス・トモグラフィー装置 |
| WO2008116010A1 (en) * | 2007-03-19 | 2008-09-25 | The General Hospital Corporation | System and method for providing noninvasive diagnosis of compartment syndrome exemplary laser speckle imaging procedure |
| EP2602651A3 (en) | 2007-03-23 | 2014-08-27 | The General Hospital Corporation | Methods, arrangements and apparatus for utilizing a wavelength-swept laser using angular scanning and dispersion procedures |
| WO2008121844A1 (en) | 2007-03-30 | 2008-10-09 | The General Hospital Corporation | System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque |
| US8045177B2 (en) | 2007-04-17 | 2011-10-25 | The General Hospital Corporation | Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy |
| US7706646B2 (en) * | 2007-04-24 | 2010-04-27 | Tomophase Corporation | Delivering light via optical waveguide and multi-view optical probe head |
| WO2008137637A2 (en) | 2007-05-04 | 2008-11-13 | The General Hospital Corporation | Methods, arrangements and systems for obtaining information associated with a sample using brillouin microscopy |
| US9622706B2 (en) | 2007-07-12 | 2017-04-18 | Volcano Corporation | Catheter for in vivo imaging |
| US9596993B2 (en) | 2007-07-12 | 2017-03-21 | Volcano Corporation | Automatic calibration systems and methods of use |
| US10219780B2 (en) | 2007-07-12 | 2019-03-05 | Volcano Corporation | OCT-IVUS catheter for concurrent luminal imaging |
| EP2173254A2 (en) | 2007-07-31 | 2010-04-14 | The General Hospital Corporation | Systems and methods for providing beam scan patterns for high speed doppler optical frequency domain imaging |
| US8040608B2 (en) | 2007-08-31 | 2011-10-18 | The General Hospital Corporation | System and method for self-interference fluorescence microscopy, and computer-accessible medium associated therewith |
| WO2009073259A2 (en) * | 2007-09-14 | 2009-06-11 | University Of Rochester | Common-path interferometer rendering amplitude and phase of scattered light |
| US20090131801A1 (en) * | 2007-10-12 | 2009-05-21 | The General Hospital Corporation | Systems and processes for optical imaging of luminal anatomic structures |
| WO2009059034A1 (en) | 2007-10-30 | 2009-05-07 | The General Hospital Corporation | System and method for cladding mode detection |
| US11123047B2 (en) | 2008-01-28 | 2021-09-21 | The General Hospital Corporation | Hybrid systems and methods for multi-modal acquisition of intravascular imaging data and counteracting the effects of signal absorption in blood |
| US9332942B2 (en) * | 2008-01-28 | 2016-05-10 | The General Hospital Corporation | Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging |
| WO2009108950A2 (en) * | 2008-02-29 | 2009-09-03 | Tomophase Corporation | Temperature profile mapping and guided thermotherapy |
| FR2930048B1 (fr) * | 2008-04-15 | 2010-05-28 | Commissariat Energie Atomique | Test non destructif d'un coupleur optique integre dans un circuit optique integre. |
| US9125562B2 (en) | 2009-07-01 | 2015-09-08 | Avinger, Inc. | Catheter-based off-axis optical coherence tomography imaging system |
| US9498600B2 (en) | 2009-07-01 | 2016-11-22 | Avinger, Inc. | Atherectomy catheter with laterally-displaceable tip |
| US8062316B2 (en) | 2008-04-23 | 2011-11-22 | Avinger, Inc. | Catheter system and method for boring through blocked vascular passages |
| US7898656B2 (en) | 2008-04-30 | 2011-03-01 | The General Hospital Corporation | Apparatus and method for cross axis parallel spectroscopy |
| EP2274572A4 (en) | 2008-05-07 | 2013-08-28 | Gen Hospital Corp | SYSTEM, METHOD AND COMPUTER MEDIUM FOR TRACKING A VASCULAR MOVEMENT IN A THREE-DIMENSIONAL CORONARTERTERIC MICROSCOPY |
| EP2288948A4 (en) | 2008-06-20 | 2011-12-28 | Gen Hospital Corp | Fused fiber optic coupler arrangement and method for use thereof |
| WO2010005874A1 (en) | 2008-07-08 | 2010-01-14 | Hinds Instruments, Inc. | High throughput birefringence measurement |
| WO2010009136A2 (en) | 2008-07-14 | 2010-01-21 | The General Hospital Corporation | Apparatus and methods for color endoscopy |
| US8364220B2 (en) | 2008-09-25 | 2013-01-29 | Covidien Lp | Medical sensor and technique for using the same |
| US8257274B2 (en) | 2008-09-25 | 2012-09-04 | Nellcor Puritan Bennett Llc | Medical sensor and technique for using the same |
| JPWO2010044322A1 (ja) * | 2008-10-17 | 2012-03-15 | コニカミノルタオプト株式会社 | 光断層測定装置 |
| EP2348967A4 (en) * | 2008-11-06 | 2014-07-02 | Univ Drexel | CONTACTLESS FREQUENCY DOMAIN NEAR-FRACTURE ABSORPTION DEVICE (FNIR) FOR THE ASSESSMENT OF TISSUE DAMAGE |
| ES2957932T3 (es) | 2008-12-10 | 2024-01-30 | Massachusetts Gen Hospital | Sistemas, aparatos y procedimientos para ampliar el rango de profundidad de imagen de tomografía de coherencia óptica mediante submuestreo óptico |
| JP2012515576A (ja) | 2009-01-20 | 2012-07-12 | ザ ジェネラル ホスピタル コーポレイション | 内視鏡生検装置、システム、及び方法 |
| JP2012515930A (ja) | 2009-01-26 | 2012-07-12 | ザ ジェネラル ホスピタル コーポレーション | 広視野の超解像顕微鏡を提供するためのシステム、方法及びコンピューターがアクセス可能な媒体 |
| CN104134928A (zh) | 2009-02-04 | 2014-11-05 | 通用医疗公司 | 利用高速光学波长调谐源的设备和方法 |
| WO2010105197A2 (en) | 2009-03-12 | 2010-09-16 | The General Hospital Corporation | Non-contact optical system, computer-accessible medium and method for measuring at least one mechanical property of tissue using coherent speckle techniques(s) |
| US8515515B2 (en) | 2009-03-25 | 2013-08-20 | Covidien Lp | Medical sensor with compressible light barrier and technique for using the same |
| US8781548B2 (en) | 2009-03-31 | 2014-07-15 | Covidien Lp | Medical sensor with flexible components and technique for using the same |
| WO2010129075A1 (en) | 2009-04-28 | 2010-11-11 | Avinger, Inc. | Guidewire support catheter |
| US8467858B2 (en) * | 2009-04-29 | 2013-06-18 | Tomophase Corporation | Image-guided thermotherapy based on selective tissue thermal treatment |
| EP4145111B1 (en) | 2009-05-28 | 2025-12-31 | Lumivascular, Inc. | Optical Coherence Tomography for Biological Imaging |
| JP5626687B2 (ja) * | 2009-06-11 | 2014-11-19 | 国立大学法人 筑波大学 | 2ビーム型光コヒーレンストモグラフィー装置 |
| US11490826B2 (en) | 2009-07-14 | 2022-11-08 | The General Hospital Corporation | Apparatus, systems and methods for measuring flow and pressure within a vessel |
| WO2011028628A2 (en) * | 2009-08-26 | 2011-03-10 | Tomophase Corporation | Optical tissue imaging based on optical frequency domain imaging |
| JP5629455B2 (ja) * | 2009-12-14 | 2014-11-19 | キヤノン株式会社 | 干渉計 |
| HRP20201813T1 (hr) | 2010-03-05 | 2021-03-19 | The General Hospital Corporation | Uređaj za pružanje elektromagnetnog zračenja na uzorak |
| US9743020B2 (en) | 2010-03-23 | 2017-08-22 | California Institute Of Technology | Super resolution optofluidic microscopes for 2D and 3D imaging |
| US9069130B2 (en) | 2010-05-03 | 2015-06-30 | The General Hospital Corporation | Apparatus, method and system for generating optical radiation from biological gain media |
| EP2573544A4 (en) * | 2010-05-19 | 2014-01-22 | Shionogi & Co | DEFINED DEVICE FOR OPTICAL ROTATION MEASUREMENT, OPTICAL ROTATION MEASUREMENT METHOD AND DEFOCOUSED GLASS FIBER SYSTEM |
| EP2575597B1 (en) | 2010-05-25 | 2022-05-04 | The General Hospital Corporation | Apparatus for providing optical imaging of structures and compositions |
| WO2011150069A2 (en) | 2010-05-25 | 2011-12-01 | The General Hospital Corporation | Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images |
| GB201009233D0 (en) | 2010-06-02 | 2010-07-21 | Univ St Andrews | Optical coherence tomography |
| WO2011153434A2 (en) | 2010-06-03 | 2011-12-08 | The General Hospital Corporation | Apparatus and method for devices for imaging structures in or at one or more luminal organs |
| US9116300B2 (en) | 2010-06-25 | 2015-08-25 | Nanjing University | Multi-mode interferometer techniques |
| US10548478B2 (en) | 2010-07-01 | 2020-02-04 | Avinger, Inc. | Balloon atherectomy catheters with imaging |
| US11382653B2 (en) | 2010-07-01 | 2022-07-12 | Avinger, Inc. | Atherectomy catheter |
| US9345510B2 (en) | 2010-07-01 | 2016-05-24 | Avinger, Inc. | Atherectomy catheters with longitudinally displaceable drive shafts |
| US9643184B2 (en) | 2010-10-26 | 2017-05-09 | California Institute Of Technology | e-Petri dishes, devices, and systems having a light detector for sampling a sequence of sub-pixel shifted projection images |
| US9569664B2 (en) * | 2010-10-26 | 2017-02-14 | California Institute Of Technology | Methods for rapid distinction between debris and growing cells |
| CN103154662A (zh) | 2010-10-26 | 2013-06-12 | 加州理工学院 | 扫描投影无透镜显微镜系统 |
| EP2632324A4 (en) | 2010-10-27 | 2015-04-22 | Gen Hospital Corp | DEVICES, SYSTEMS AND METHOD FOR MEASURING BLOOD PRESSURE IN AT LEAST ONE VESSEL |
| CN103282764A (zh) * | 2010-10-29 | 2013-09-04 | 尼尔科学公司 | 用于分析物检测的方法和装置 |
| KR101652399B1 (ko) * | 2010-12-07 | 2016-09-12 | 삼성전자주식회사 | 3차원 디스플레이 장치 및 3차원 영상 디스플레이 방법 |
| US11141063B2 (en) | 2010-12-23 | 2021-10-12 | Philips Image Guided Therapy Corporation | Integrated system architectures and methods of use |
| US11040140B2 (en) | 2010-12-31 | 2021-06-22 | Philips Image Guided Therapy Corporation | Deep vein thrombosis therapeutic methods |
| CN103534627A (zh) | 2011-03-03 | 2014-01-22 | 加州理工学院 | 光导像素 |
| CA2831306C (en) | 2011-03-28 | 2018-11-20 | Avinger, Inc. | Occlusion-crossing devices, imaging, and atherectomy devices |
| US9949754B2 (en) | 2011-03-28 | 2018-04-24 | Avinger, Inc. | Occlusion-crossing devices |
| WO2012149175A1 (en) | 2011-04-29 | 2012-11-01 | The General Hospital Corporation | Means for determining depth-resolved physical and/or optical properties of scattering media |
| EP2715422B1 (en) | 2011-05-23 | 2021-07-21 | Intuitive Surgical Operations, Inc. | Variable polarization separation via beam splitter rotation |
| US9574941B2 (en) * | 2011-05-31 | 2017-02-21 | Tornado Spectral Systems, Inc. | Dispersed fourier transform spectrometer, methods and systems |
| JP2014523536A (ja) | 2011-07-19 | 2014-09-11 | ザ ジェネラル ホスピタル コーポレイション | 光コヒーレンストモグラフィーにおいて偏波モード分散補償を提供するためのシステム、方法、装置およびコンピュータアクセス可能な媒体 |
| WO2013013220A2 (en) | 2011-07-20 | 2013-01-24 | University Of Washington Through Its Center For Commercialization | Photonic blood typing |
| WO2013029047A1 (en) | 2011-08-25 | 2013-02-28 | The General Hospital Corporation | Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures |
| WO2013033592A1 (en) | 2011-08-31 | 2013-03-07 | Volcano Corporation | Optical-electrical rotary joint and methods of use |
| WO2013059363A1 (en) | 2011-10-17 | 2013-04-25 | Avinger, Inc. | Atherectomy catheters and non-contact actuation mechanism for catheters |
| US9341783B2 (en) | 2011-10-18 | 2016-05-17 | The General Hospital Corporation | Apparatus and methods for producing and/or providing recirculating optical delay(s) |
| US20130107274A1 (en) * | 2011-10-28 | 2013-05-02 | Tomophase Corporation | Optical imaging and mapping using propagation modes of light |
| US9345406B2 (en) | 2011-11-11 | 2016-05-24 | Avinger, Inc. | Occlusion-crossing devices, atherectomy devices, and imaging |
| US10031138B2 (en) | 2012-01-20 | 2018-07-24 | University Of Washington Through Its Center For Commercialization | Hierarchical films having ultra low fouling and high recognition element loading properties |
| WO2013134361A1 (en) * | 2012-03-08 | 2013-09-12 | Alcatel-Lucent Usa Inc. | Multi-mode optical communication with mode mixtures |
| US20130317368A1 (en) | 2012-03-12 | 2013-11-28 | Ivwatch, Llc | System for Mitigating the Effects of Tissue Blood Volume Changes to Aid in Diagnosing Infiltration or Extravasation in Animalia Tissue |
| US9629528B2 (en) | 2012-03-30 | 2017-04-25 | The General Hospital Corporation | Imaging system, method and distal attachment for multidirectional field of view endoscopy |
| US11406412B2 (en) | 2012-05-14 | 2022-08-09 | Avinger, Inc. | Atherectomy catheters with imaging |
| WO2013172974A1 (en) | 2012-05-14 | 2013-11-21 | Avinger, Inc. | Atherectomy catheter drive assemblies |
| EP2849636B1 (en) | 2012-05-14 | 2020-04-22 | Avinger, Inc. | Optical coherence tomography with graded index fiber for biological imaging |
| EP2852315A4 (en) | 2012-05-21 | 2016-06-08 | Gen Hospital Corp | DEVICE, APPARATUS AND METHOD FOR CAPSULE MICROSCOPY |
| DE102012104874B4 (de) * | 2012-06-05 | 2016-05-19 | Technische Universität München | Optisches Messsystem mit Polarisationskompensation, sowie entsprechendes Verfahren |
| US9766126B2 (en) | 2013-07-12 | 2017-09-19 | Zyomed Corp. | Dynamic radially controlled light input to a noninvasive analyzer apparatus and method of use thereof |
| JP6227652B2 (ja) | 2012-08-22 | 2017-11-08 | ザ ジェネラル ホスピタル コーポレイション | ソフトリソグラフィを用いてミニチュア内視鏡を製作するためのシステム、方法、およびコンピュータ・アクセス可能媒体 |
| US11284916B2 (en) | 2012-09-06 | 2022-03-29 | Avinger, Inc. | Atherectomy catheters and occlusion crossing devices |
| US10335173B2 (en) | 2012-09-06 | 2019-07-02 | Avinger, Inc. | Re-entry stylet for catheter |
| US9498247B2 (en) | 2014-02-06 | 2016-11-22 | Avinger, Inc. | Atherectomy catheters and occlusion crossing devices |
| EP2903532B1 (en) | 2012-10-05 | 2022-08-17 | Nathaniel J. Kemp | System for operation of three-dimesional imaging systems |
| US9292918B2 (en) | 2012-10-05 | 2016-03-22 | Volcano Corporation | Methods and systems for transforming luminal images |
| US10568586B2 (en) | 2012-10-05 | 2020-02-25 | Volcano Corporation | Systems for indicating parameters in an imaging data set and methods of use |
| US11272845B2 (en) | 2012-10-05 | 2022-03-15 | Philips Image Guided Therapy Corporation | System and method for instant and automatic border detection |
| US9307926B2 (en) | 2012-10-05 | 2016-04-12 | Volcano Corporation | Automatic stent detection |
| US9286673B2 (en) | 2012-10-05 | 2016-03-15 | Volcano Corporation | Systems for correcting distortions in a medical image and methods of use thereof |
| WO2014055880A2 (en) | 2012-10-05 | 2014-04-10 | David Welford | Systems and methods for amplifying light |
| US9367965B2 (en) | 2012-10-05 | 2016-06-14 | Volcano Corporation | Systems and methods for generating images of tissue |
| US9324141B2 (en) | 2012-10-05 | 2016-04-26 | Volcano Corporation | Removal of A-scan streaking artifact |
| US10070827B2 (en) | 2012-10-05 | 2018-09-11 | Volcano Corporation | Automatic image playback |
| US9858668B2 (en) | 2012-10-05 | 2018-01-02 | Volcano Corporation | Guidewire artifact removal in images |
| EP2720388A1 (en) | 2012-10-15 | 2014-04-16 | Koninklijke Philips N.V. | An optical frequency domain reflectometry (OFDR) system |
| US9840734B2 (en) | 2012-10-22 | 2017-12-12 | Raindance Technologies, Inc. | Methods for analyzing DNA |
| US9417127B2 (en) * | 2012-10-23 | 2016-08-16 | Eric Udd | Fiber grating sensor system for measuring key parameters during high speed |
| JP6038619B2 (ja) * | 2012-12-04 | 2016-12-07 | 株式会社日立エルジーデータストレージ | 偏光感受型光計測装置 |
| WO2014093374A1 (en) | 2012-12-13 | 2014-06-19 | Volcano Corporation | Devices, systems, and methods for targeted cannulation |
| US10942022B2 (en) | 2012-12-20 | 2021-03-09 | Philips Image Guided Therapy Corporation | Manual calibration of imaging system |
| US11406498B2 (en) | 2012-12-20 | 2022-08-09 | Philips Image Guided Therapy Corporation | Implant delivery system and implants |
| WO2014113188A2 (en) | 2012-12-20 | 2014-07-24 | Jeremy Stigall | Locating intravascular images |
| US10939826B2 (en) | 2012-12-20 | 2021-03-09 | Philips Image Guided Therapy Corporation | Aspirating and removing biological material |
| US9709379B2 (en) | 2012-12-20 | 2017-07-18 | Volcano Corporation | Optical coherence tomography system that is reconfigurable between different imaging modes |
| US10595820B2 (en) | 2012-12-20 | 2020-03-24 | Philips Image Guided Therapy Corporation | Smooth transition catheters |
| JP2016502884A (ja) | 2012-12-21 | 2016-02-01 | ダグラス メイヤー, | 延在カテーテル本体テレスコープを有する回転可能超音波撮像カテーテル |
| WO2014099672A1 (en) | 2012-12-21 | 2014-06-26 | Andrew Hancock | System and method for multipath processing of image signals |
| JP2016508233A (ja) | 2012-12-21 | 2016-03-17 | ナサニエル ジェイ. ケンプ, | 光学スイッチを用いた電力効率のよい光学バッファリング |
| WO2014099760A1 (en) | 2012-12-21 | 2014-06-26 | Mai Jerome | Ultrasound imaging with variable line density |
| US10058284B2 (en) | 2012-12-21 | 2018-08-28 | Volcano Corporation | Simultaneous imaging, monitoring, and therapy |
| JP2016507272A (ja) | 2012-12-21 | 2016-03-10 | ヴォルカノ コーポレイションVolcano Corporation | 機能的利得の測定技術及び表示 |
| JP2016508757A (ja) | 2012-12-21 | 2016-03-24 | ジェイソン スペンサー, | 医療データのグラフィカル処理のためのシステムおよび方法 |
| WO2014100530A1 (en) | 2012-12-21 | 2014-06-26 | Whiseant Chester | System and method for catheter steering and operation |
| US9226711B2 (en) | 2012-12-21 | 2016-01-05 | Volcano Corporation | Laser direct structured catheter connection for intravascular device |
| US9486143B2 (en) | 2012-12-21 | 2016-11-08 | Volcano Corporation | Intravascular forward imaging device |
| CA2896006A1 (en) | 2012-12-21 | 2014-06-26 | David Welford | Systems and methods for narrowing a wavelength emission of light |
| US9612105B2 (en) | 2012-12-21 | 2017-04-04 | Volcano Corporation | Polarization sensitive optical coherence tomography system |
| JP6053138B2 (ja) | 2013-01-24 | 2016-12-27 | 株式会社日立エルジーデータストレージ | 光断層観察装置及び光断層観察方法 |
| EP2948758B1 (en) | 2013-01-28 | 2024-03-13 | The General Hospital Corporation | Apparatus for providing diffuse spectroscopy co-registered with optical frequency domain imaging |
| US10893806B2 (en) | 2013-01-29 | 2021-01-19 | The General Hospital Corporation | Apparatus, systems and methods for providing information regarding the aortic valve |
| WO2014121082A1 (en) | 2013-02-01 | 2014-08-07 | The General Hospital Corporation | Objective lens arrangement for confocal endomicroscopy |
| US10226597B2 (en) | 2013-03-07 | 2019-03-12 | Volcano Corporation | Guidewire with centering mechanism |
| WO2014138555A1 (en) | 2013-03-07 | 2014-09-12 | Bernhard Sturm | Multimodal segmentation in intravascular images |
| CN105228518B (zh) | 2013-03-12 | 2018-10-09 | 火山公司 | 用于诊断冠状微脉管疾病的系统和方法 |
| US20140276923A1 (en) | 2013-03-12 | 2014-09-18 | Volcano Corporation | Vibrating catheter and methods of use |
| US9301687B2 (en) | 2013-03-13 | 2016-04-05 | Volcano Corporation | System and method for OCT depth calibration |
| JP6339170B2 (ja) | 2013-03-13 | 2018-06-06 | ジンヒョン パーク | 回転式血管内超音波装置から画像を生成するためのシステム及び方法 |
| US11026591B2 (en) | 2013-03-13 | 2021-06-08 | Philips Image Guided Therapy Corporation | Intravascular pressure sensor calibration |
| US12343198B2 (en) | 2013-03-14 | 2025-07-01 | Philips Image Guided Therapy Corporation | Delivery catheter having imaging capabilities |
| US10219887B2 (en) | 2013-03-14 | 2019-03-05 | Volcano Corporation | Filters with echogenic characteristics |
| US10292677B2 (en) | 2013-03-14 | 2019-05-21 | Volcano Corporation | Endoluminal filter having enhanced echogenic properties |
| US20160030151A1 (en) | 2013-03-14 | 2016-02-04 | Volcano Corporation | Filters with echogenic characteristics |
| EP2967367B1 (en) | 2013-03-15 | 2019-02-20 | Avinger, Inc. | Optical pressure sensor assembly |
| WO2014144709A2 (en) | 2013-03-15 | 2014-09-18 | The General Hospital Corporation | Methods and systems for characterizing an object |
| WO2014142954A1 (en) | 2013-03-15 | 2014-09-18 | Avinger, Inc. | Tissue collection device for catheter |
| EP2967371B1 (en) | 2013-03-15 | 2024-05-15 | Avinger, Inc. | Chronic total occlusion crossing devices with imaging |
| JP6094300B2 (ja) * | 2013-03-25 | 2017-03-15 | 株式会社東京精密 | 白色干渉測定方法及び白色干渉測定装置 |
| EP2792996A1 (en) * | 2013-04-17 | 2014-10-22 | Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO | Interferometric distance sensing device and method |
| WO2014179292A1 (en) * | 2013-04-29 | 2014-11-06 | The Charlotte-Mecklenburg Hospital Authority D/B/A Carolinas Healthcare System | Device, system, and method for insertion of a medical device into a subject |
| US9784681B2 (en) | 2013-05-13 | 2017-10-10 | The General Hospital Corporation | System and method for efficient detection of the phase and amplitude of a periodic modulation associated with self-interfering fluorescence |
| WO2015006353A1 (en) | 2013-07-08 | 2015-01-15 | Avinger, Inc. | Identification of elastic lamina to guide interventional therapy |
| EP3021735A4 (en) | 2013-07-19 | 2017-04-19 | The General Hospital Corporation | Determining eye motion by imaging retina. with feedback |
| EP3692887B1 (en) | 2013-07-19 | 2024-03-06 | The General Hospital Corporation | Imaging apparatus which utilizes multidirectional field of view endoscopy |
| EP3910282B1 (en) | 2013-07-26 | 2024-01-17 | The General Hospital Corporation | Method of providing a laser radiation with a laser arrangement utilizing optical dispersion for applications in fourier-domain optical coherence tomography |
| JP6517832B2 (ja) | 2013-11-18 | 2019-05-22 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 誘導血栓分散カテーテル |
| CN105744901B (zh) | 2013-11-18 | 2020-08-04 | 皇家飞利浦有限公司 | 用于血栓疏散的方法和设备 |
| US9733460B2 (en) | 2014-01-08 | 2017-08-15 | The General Hospital Corporation | Method and apparatus for microscopic imaging |
| EP3094241B1 (en) | 2014-01-14 | 2018-07-04 | Volcano Corporation | Systems and methods for evaluating hemodialysis arteriovenous fistula maturation |
| US11260160B2 (en) | 2014-01-14 | 2022-03-01 | Philips Image Guided Therapy Corporation | Systems and methods for improving an AV access site |
| WO2015108942A1 (en) | 2014-01-14 | 2015-07-23 | Volcano Corporation | Vascular access evaluation and treatment |
| JP2017509366A (ja) | 2014-01-14 | 2017-04-06 | ボルケーノ コーポレイション | 血管アクセス部位創成のためのカテーテルアセンブリ |
| WO2015108973A1 (en) | 2014-01-14 | 2015-07-23 | Volcano Corporation | Methods and systems for clearing thrombus from a vascular access site |
| US10238816B2 (en) | 2014-01-14 | 2019-03-26 | Volcano Corporation | Devices and methods for forming vascular access |
| US10736494B2 (en) | 2014-01-31 | 2020-08-11 | The General Hospital Corporation | System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device |
| MX2016010141A (es) | 2014-02-06 | 2017-04-06 | Avinger Inc | Cateteres de aterectomia y dispositivos de cruce de oclusion. |
| US10228556B2 (en) | 2014-04-04 | 2019-03-12 | The General Hospital Corporation | Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s) |
| WO2015156945A1 (en) | 2014-04-11 | 2015-10-15 | Jeremy Stigall | Imaging and treatment device |
| MX2017000303A (es) | 2014-07-08 | 2017-07-10 | Avinger Inc | Dispositivos para oclusion transversal cronica total de alta velocidad. |
| WO2016009337A2 (en) | 2014-07-15 | 2016-01-21 | Koninklijke Philips N.V. | Devices and methods for intrahepatic shunts |
| US10912462B2 (en) | 2014-07-25 | 2021-02-09 | The General Hospital Corporation | Apparatus, devices and methods for in vivo imaging and diagnosis |
| DE102014216829B4 (de) * | 2014-08-25 | 2021-08-05 | Trumpf Laser- Und Systemtechnik Gmbh | Vorrichtung und Verfahren zur temperaturkompensierten interferometrischen Abstandsmessung beim Laserbearbeiten von Werkstücken |
| EP3201310B1 (en) * | 2014-10-01 | 2021-02-17 | Purdue Research Foundation | Microorganism identification |
| WO2016094940A1 (en) * | 2014-12-14 | 2016-06-23 | Cylite Pty Ltd | Multichannel optical receivers |
| EP3234500A4 (en) * | 2014-12-19 | 2018-07-04 | University of Utah Research Foundation | Interferometry system and associated methods |
| KR102356454B1 (ko) * | 2015-02-17 | 2022-01-27 | 삼성전자주식회사 | 이중 커플러 소자, 상기 이중 커플러를 포함하는 분광기, 및 상기 분광기를 포함하는 비침습형 생체 센서 |
| WO2016132241A1 (en) | 2015-02-20 | 2016-08-25 | Koninklijke Philips N.V. | Atherectomy apparatus with imaging |
| US9970819B2 (en) * | 2015-03-23 | 2018-05-15 | Si-Ware Systems | High performance parallel spectrometer device |
| US10905394B2 (en) | 2015-04-20 | 2021-02-02 | Philips Image Guided Therapy Corporation | Dual lumen diagnostic catheter |
| EP3106828B1 (en) | 2015-06-16 | 2023-06-07 | Academisch Medisch Centrum | Common-path integrated low coherence interferometry system and method therefor |
| EP3322338B1 (en) | 2015-07-13 | 2025-02-12 | Avinger, Inc. | Micro-molded anamorphic reflector lens for image guided therapeutic/diagnostic catheters |
| RU2615035C1 (ru) * | 2015-09-22 | 2017-04-03 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия" Министерства Здравоохранения Российской Федерации (ГБОУ ВПО НижГМА Минздрава России) | Устройство для регистрации изображений кросс-поляризационной низкокогерентной оптической интерферометрии |
| WO2017132247A1 (en) | 2016-01-25 | 2017-08-03 | Avinger, Inc. | Oct imaging catheter with lag correction |
| US10732113B2 (en) * | 2016-02-26 | 2020-08-04 | Single Technologies Ab | Method and device for high throughput imaging |
| US9554738B1 (en) * | 2016-03-30 | 2017-01-31 | Zyomed Corp. | Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing |
| WO2017173370A1 (en) | 2016-04-01 | 2017-10-05 | Avinger, Inc. | Atherectomy catheter with serrated cutter |
| WO2018044363A2 (en) * | 2016-05-11 | 2018-03-08 | Massachusetts Institute Of Technology | Methods and apparatus for mode-locking on-chip lasers |
| CN109152534A (zh) | 2016-05-20 | 2019-01-04 | 皇家飞利浦有限公司 | 基于血管内压力和壁厚测量的用于针对肾脏去神经支配的患者分层的设备、系统和方法 |
| EP3263018A1 (en) | 2016-06-29 | 2018-01-03 | Koninklijke Philips N.V. | Devices and methods for stratification of patients for renal denervation based on intravascular pressure and wall thickness measurements |
| WO2017198800A1 (en) | 2016-05-20 | 2017-11-23 | Koninklijke Philips N.V. | Devices and methods for stratification of patients for renal denervation based on intravascular pressure and cross-sectional lumen measurements |
| US9952269B2 (en) * | 2016-05-20 | 2018-04-24 | Kerim Akel | Measurement of complex dielectric constant and permeability |
| JP2019518543A (ja) | 2016-06-03 | 2019-07-04 | アビンガー・インコーポレイテッドAvinger, Inc. | 着脱可能な遠位端部を有するカテーテル装置 |
| US11162781B2 (en) | 2016-06-23 | 2021-11-02 | University Of Utah Research Foundation | Interferometry systems and methods |
| WO2017223542A1 (en) | 2016-06-23 | 2017-12-28 | University Of Utah Research Foundation | Interferometry system and associated methods |
| US11224459B2 (en) | 2016-06-30 | 2022-01-18 | Avinger, Inc. | Atherectomy catheter with shapeable distal tip |
| CN106595863B (zh) * | 2016-12-29 | 2018-05-15 | 中国科学院光电技术研究所 | 一种提高液晶可调谐滤波器光谱重建精度和分辨率的方法 |
| DE102017115922C5 (de) * | 2017-07-14 | 2023-03-23 | Precitec Gmbh & Co. Kg | Verfahren und Vorrichtung zur Messung und Einstellung eines Abstands zwischen einem Bearbeitungskopf und einem Werkstück sowie dazugehöriges Verfahren zur Regelung |
| EP3545821A1 (en) * | 2018-03-27 | 2019-10-02 | Koninklijke Philips N.V. | Device, system and method for extracting physiological information indicative of at least one vital sign of a subject |
| EP3781021B1 (en) | 2018-04-19 | 2023-03-22 | Avinger, Inc. | Occlusion-crossing devices |
| EP3784112A4 (en) | 2018-04-26 | 2022-01-12 | Voxeleron LLC | METHODS AND SYSTEM FOR DISEASE ANALYSIS AND INTERPRETATION |
| JP2021529038A (ja) | 2018-06-28 | 2021-10-28 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 活性治療薬の外部標的化送達 |
| WO2020002177A1 (en) | 2018-06-28 | 2020-01-02 | Koninklijke Philips N.V. | Internal ultrasound assisted local therapeutic delivery |
| CN109062018A (zh) * | 2018-10-19 | 2018-12-21 | 许之敏 | 一种三波长反射式数字全息显微镜 |
| EP3895120A4 (en) * | 2018-12-10 | 2022-08-24 | Voxeleron LLC | SYSTEM AND METHOD FOR OBTAINING MEASUREMENTS FROM IMAGING DATA |
| US11500154B1 (en) * | 2019-10-18 | 2022-11-15 | Apple Inc. | Asymmetric optical power splitting system and method |
| US11793400B2 (en) | 2019-10-18 | 2023-10-24 | Avinger, Inc. | Occlusion-crossing devices |
| IL272180B (en) * | 2020-01-22 | 2022-07-01 | Evgeny Seider | A non-invasive device for testing blood sugar |
| US12553885B2 (en) | 2020-05-07 | 2026-02-17 | Hand Held Products, Inc. | Apparatuses, systems, and methods for sample testing |
| US12196672B2 (en) | 2020-05-07 | 2025-01-14 | Hand Held Products, Inc. | Apparatuses, systems, and methods for sample testing |
| US12498328B2 (en) | 2020-05-07 | 2025-12-16 | Hand Held Products, Inc. | Apparatuses, systems, and methods for sample testing |
| CN111678894B (zh) * | 2020-06-30 | 2024-07-23 | 上海师范大学 | 一种正入射式透射光相位信息表征光路系统及方法 |
| US12372724B2 (en) | 2020-09-23 | 2025-07-29 | Apple Inc. | Light splitting device |
| US11906778B2 (en) | 2020-09-25 | 2024-02-20 | Apple Inc. | Achromatic light splitting device with a high V number and a low V number waveguide |
| US11846574B2 (en) | 2020-10-29 | 2023-12-19 | Hand Held Products, Inc. | Apparatuses, systems, and methods for sample capture and extraction |
| US12567569B2 (en) * | 2020-11-12 | 2026-03-03 | Applied Materials, Inc. | Optical cable for interferometric endpoint detection |
| US12487407B2 (en) | 2021-09-24 | 2025-12-02 | Apple Inc. | Compact light splitting devices and methods |
| US11971574B2 (en) | 2021-09-24 | 2024-04-30 | Apple Inc. | Multi-mode devices for multiplexing and de-multiplexing |
| EP4273599A1 (en) | 2022-05-05 | 2023-11-08 | Apple Inc. | Compact optical splitter |
| US12372719B2 (en) | 2022-09-06 | 2025-07-29 | Apple Inc. | Compact optical coupler |
| US12359972B2 (en) * | 2022-10-17 | 2025-07-15 | Lawrence Livermore National Security, Llc | Three phase spectral interferometry |
| US12578076B2 (en) | 2023-06-05 | 2026-03-17 | Hamamatsu Photonics K.K. | Dual-output laser-driven light source |
| US12085387B1 (en) * | 2023-09-23 | 2024-09-10 | Hamamatsu Photonics K.K. | Optical coherence tomography system for subsurface inspection |
| US20260104246A1 (en) * | 2024-10-10 | 2026-04-16 | Wojciech Jan Walecki | Polarization-sensitive probe for low coherence interferometer system |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1172431A (ja) * | 1997-08-28 | 1999-03-16 | Olympus Optical Co Ltd | 光断層イメージング装置 |
| JP2000131222A (ja) * | 1998-10-22 | 2000-05-12 | Olympus Optical Co Ltd | 光断層画像装置 |
| JP2001066245A (ja) * | 1999-08-26 | 2001-03-16 | Japan Science & Technology Corp | 光波反射断層像観測装置 |
| JP2001241929A (ja) * | 2000-03-01 | 2001-09-07 | Nikon Corp | 非球面形状測定方法、非球面形状測定装置、投影光学系、および露光方法 |
| JP2001330558A (ja) * | 2000-05-25 | 2001-11-30 | Japan Science & Technology Corp | 2次元光ヘテロダイン検出法を用いた光画像計測装置 |
| JP2002013907A (ja) * | 2000-06-30 | 2002-01-18 | Mitsutoyo Corp | 位相シフト干渉縞同時撮像装置における平面形状計測方法 |
| US6501551B1 (en) * | 1991-04-29 | 2002-12-31 | Massachusetts Institute Of Technology | Fiber optic imaging endoscope interferometer with at least one faraday rotator |
| JP2003172690A (ja) * | 2001-12-07 | 2003-06-20 | Olympus Optical Co Ltd | 光イメージング装置 |
| US6725073B1 (en) * | 1999-08-17 | 2004-04-20 | Board Of Regents, The University Of Texas System | Methods for noninvasive analyte sensing |
Family Cites Families (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55130640A (en) * | 1979-03-30 | 1980-10-09 | Olympus Optical Co | Endoscope |
| IT1206462B (it) * | 1984-08-07 | 1989-04-27 | Anic Spa | Fotometro a luce impulsata a lunghezza d'onda multipla per monitoraggio non-invasivo. |
| US4878492A (en) * | 1987-10-08 | 1989-11-07 | C. R. Bard, Inc. | Laser balloon catheter |
| JPH0711613B2 (ja) * | 1988-02-10 | 1995-02-08 | 日立電線株式会社 | 偏波面保存光ファイバ用ロータリージョイント |
| US4991938A (en) * | 1989-04-07 | 1991-02-12 | Gte Laboratories Incorporated | Quasi-achromatic optical isolators and circulators using prisms with total internal fresnel reflection |
| DE69029712T2 (de) | 1989-11-20 | 1997-05-28 | Hamamatsu Photonics Kk | Mit einem Laserstrahlengenerator versehene Einrichtung für die Diagnose und Behandlung von Krebs |
| US5202745A (en) * | 1990-11-07 | 1993-04-13 | Hewlett-Packard Company | Polarization independent optical coherence-domain reflectometry |
| US5784162A (en) * | 1993-08-18 | 1998-07-21 | Applied Spectral Imaging Ltd. | Spectral bio-imaging methods for biological research, medical diagnostics and therapy |
| US6111645A (en) * | 1991-04-29 | 2000-08-29 | Massachusetts Institute Of Technology | Grating based phase control optical delay line |
| US6134003A (en) * | 1991-04-29 | 2000-10-17 | Massachusetts Institute Of Technology | Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope |
| WO1992019930A1 (en) * | 1991-04-29 | 1992-11-12 | Massachusetts Institute Of Technology | Method and apparatus for optical imaging and measurement |
| US6485413B1 (en) * | 1991-04-29 | 2002-11-26 | The General Hospital Corporation | Methods and apparatus for forward-directed optical scanning instruments |
| JPH0538369A (ja) | 1991-08-05 | 1993-02-19 | Ishikawajima Harima Heavy Ind Co Ltd | 癌の治療装置 |
| TW275570B (https=) * | 1994-05-05 | 1996-05-11 | Boehringer Mannheim Gmbh | |
| US6423055B1 (en) * | 1999-07-14 | 2002-07-23 | Cardiofocus, Inc. | Phototherapeutic wave guide apparatus |
| US5803909A (en) | 1994-10-06 | 1998-09-08 | Hitachi, Ltd. | Optical system for measuring metabolism in a body and imaging method |
| WO1996023315A1 (en) * | 1995-01-24 | 1996-08-01 | International Business Machines Corporation | Cathode ray tube display apparatus with reduced stray magnetic fields |
| US5659392A (en) * | 1995-03-22 | 1997-08-19 | Eastman Kodak Company | Associated dual interferometric measurement apparatus for determining a physical property of an object |
| EP0889703B1 (en) * | 1996-02-05 | 2001-11-21 | Diasense, Inc. | Apparatus for non-invasive glucose sensing |
| US5912762A (en) | 1996-08-12 | 1999-06-15 | Li; Li | Thin film polarizing device |
| CA2283949A1 (en) * | 1997-03-13 | 1998-09-17 | Haishan Zeng | Methods and apparatus for detecting the rejection of transplanted tissue |
| RU2148378C1 (ru) | 1998-03-06 | 2000-05-10 | Геликонов Валентин Михайлович | Устройство для оптической когерентной томографии, оптоволоконное сканирующее устройство и способ диагностики биоткани in vivo |
| US6201608B1 (en) * | 1998-03-13 | 2001-03-13 | Optical Biopsy Technologies, Inc. | Method and apparatus for measuring optical reflectivity and imaging through a scattering medium |
| US6034774A (en) * | 1998-06-26 | 2000-03-07 | Eastman Kodak Company | Method for determining the retardation of a material using non-coherent light interferometery |
| JP4286351B2 (ja) * | 1998-11-13 | 2009-06-24 | 富士通株式会社 | 光アッド/ドロップ回路 |
| US6522407B2 (en) * | 1999-01-22 | 2003-02-18 | The Regents Of The University Of California | Optical detection dental disease using polarized light |
| EP1147398B1 (en) * | 1999-01-29 | 2004-06-09 | June Iris Medford | Optical coherence microscope and method for rapid 3d-in-vivo visualization of biological functions |
| US6615072B1 (en) | 1999-02-04 | 2003-09-02 | Olympus Optical Co., Ltd. | Optical imaging device |
| JP4076003B2 (ja) * | 1999-02-19 | 2008-04-16 | 株式会社日立製作所 | 生体光計測装置 |
| WO2000057793A1 (fr) * | 1999-03-29 | 2000-10-05 | Hitachi Medical Corporation | Instrument de mesure optique biologique |
| US6377840B1 (en) * | 1999-06-03 | 2002-04-23 | Hutchinson Technology Incorporated | Signal acquisition and processing system for reduced output signal drift in a spectrophotometric instrument |
| ATE258768T1 (de) * | 1999-08-05 | 2004-02-15 | Broncus Tech Inc | Verfahren und vorrichtungen zur herstellung von kollateralen kanälen in den lungen |
| AU6894500A (en) | 1999-08-06 | 2001-03-05 | Board Of Regents, The University Of Texas System | Optoacoustic monitoring of blood oxygenation |
| US6687010B1 (en) | 1999-09-09 | 2004-02-03 | Olympus Corporation | Rapid depth scanning optical imaging device |
| US6738144B1 (en) | 1999-12-17 | 2004-05-18 | University Of Central Florida | Non-invasive method and low-coherence apparatus system analysis and process control |
| EP1264170B1 (en) * | 2000-03-10 | 2009-02-04 | Textron Systems Corporation | Optical probes and methods for spectral analysis |
| CN1252468C (zh) * | 2000-05-02 | 2006-04-19 | 富士胶片株式会社 | 超声波探头及使用其的超声波诊断装置 |
| US6451009B1 (en) * | 2000-09-12 | 2002-09-17 | The Regents Of The University Of California | OCDR guided laser ablation device |
| US6585639B1 (en) * | 2000-10-27 | 2003-07-01 | Pulmonx | Sheath and method for reconfiguring lung viewing scope |
| EP1362252A4 (en) * | 2001-01-12 | 2006-02-01 | Univ Texas | METHOD AND DEVICE FOR THE OPTICAL DIFFERENTIAL PHASE COHERENCE TOMOGRAPHY |
| US20020126347A1 (en) * | 2001-03-07 | 2002-09-12 | Hogan Josh N. | High data rate multiple wavelength encoding |
| JP2002263055A (ja) * | 2001-03-12 | 2002-09-17 | Olympus Optical Co Ltd | 内視鏡先端フード |
| US6570659B2 (en) * | 2001-03-16 | 2003-05-27 | Lightlab Imaging, Llc | Broadband light source system and method and light source combiner |
| US6498492B1 (en) * | 2001-03-23 | 2002-12-24 | Rosemount Analytical Inc. | Process of measuring conductivity using a pH analyzer |
| AU2002337666A1 (en) * | 2001-08-03 | 2003-02-17 | Joseph A. Izatt | Aspects of basic oct engine technologies for high speed optical coherence tomography and light source and other improvements in oct |
| US6847453B2 (en) | 2001-11-05 | 2005-01-25 | Optiphase, Inc. | All fiber autocorrelator |
| WO2003047145A2 (en) * | 2001-11-26 | 2003-06-05 | E. I. Du Pont De Nemours And Company | Methods and devices to minimize the optical loss when multiplexing a plurality of tunable laser sources |
| US6746465B2 (en) * | 2001-12-14 | 2004-06-08 | The Regents Of The University Of California | Catheter based balloon for therapy modification and positioning of tissue |
| CN1623085A (zh) | 2002-01-24 | 2005-06-01 | 通用医疗公司 | 使用光谱带并行检测的低相干干涉测量法(lci)和光学相干层析成像(oct)信号的测距和降噪的装置和方法 |
| US6709402B2 (en) * | 2002-02-22 | 2004-03-23 | Datex-Ohmeda, Inc. | Apparatus and method for monitoring respiration with a pulse oximeter |
| US20030187319A1 (en) * | 2002-03-29 | 2003-10-02 | Olympus Optical Co., Ltd. | Sentinel lymph node detecting apparatus, and method thereof |
| US6819810B1 (en) * | 2002-04-09 | 2004-11-16 | Oplink Communications, Inc. | Depolarizer |
| US20050053109A1 (en) * | 2002-06-03 | 2005-03-10 | Josh Hogan | Integrated multiple wavelength system |
| US6891984B2 (en) | 2002-07-25 | 2005-05-10 | Lightlab Imaging, Llc | Scanning miniature optical probes with optical distortion correction and rotational control |
| US6813333B2 (en) * | 2002-11-27 | 2004-11-02 | Ge Medical Systems Global Technology Company, Llc | Methods and apparatus for detecting structural, perfusion, and functional abnormalities |
| US7023563B2 (en) | 2003-02-14 | 2006-04-04 | Chian Chiu Li | Interferometric optical imaging and storage devices |
| JP2004317437A (ja) | 2003-04-18 | 2004-11-11 | Olympus Corp | 光イメージング装置 |
| US7263394B2 (en) | 2003-06-04 | 2007-08-28 | Tomophase Corporation | Coherence-gated optical glucose monitor |
| US6943881B2 (en) * | 2003-06-04 | 2005-09-13 | Tomophase Corporation | Measurements of optical inhomogeneity and other properties in substances using propagation modes of light |
| US7353055B2 (en) * | 2003-06-18 | 2008-04-01 | Hogan Josh N | Non-invasive analysis system |
| US7120340B2 (en) * | 2003-06-19 | 2006-10-10 | Corning Incorporated | Single polarization optical fiber laser and amplifier |
| US7254429B2 (en) * | 2004-08-11 | 2007-08-07 | Glucolight Corporation | Method and apparatus for monitoring glucose levels in a biological tissue |
| US8498681B2 (en) | 2004-10-05 | 2013-07-30 | Tomophase Corporation | Cross-sectional mapping of spectral absorbance features |
| US7970458B2 (en) | 2004-10-12 | 2011-06-28 | Tomophase Corporation | Integrated disease diagnosis and treatment system |
| US7248907B2 (en) * | 2004-10-23 | 2007-07-24 | Hogan Josh N | Correlation of concurrent non-invasively acquired signals |
| US7428053B2 (en) * | 2005-07-08 | 2008-09-23 | Imalux Corporation | Common path frequency domain optical coherence reflectometry/tomography device |
| US7831298B1 (en) * | 2005-10-04 | 2010-11-09 | Tomophase Corporation | Mapping physiological functions of tissues in lungs and other organs |
| US20080033300A1 (en) * | 2006-08-04 | 2008-02-07 | Anh Hoang | Systems and methods for monitoring temperature during electrosurgery or laser therapy |
| EP2095064A4 (en) * | 2006-11-03 | 2013-04-10 | Volcano Corp | ANALYTE SENSOR METHOD AND APPARATUS |
| US7706646B2 (en) | 2007-04-24 | 2010-04-27 | Tomophase Corporation | Delivering light via optical waveguide and multi-view optical probe head |
| WO2009108950A2 (en) | 2008-02-29 | 2009-09-03 | Tomophase Corporation | Temperature profile mapping and guided thermotherapy |
| US8467858B2 (en) * | 2009-04-29 | 2013-06-18 | Tomophase Corporation | Image-guided thermotherapy based on selective tissue thermal treatment |
-
2004
- 2004-06-03 US US10/860,094 patent/US6943881B2/en not_active Expired - Lifetime
- 2004-06-04 WO PCT/US2004/017649 patent/WO2005001522A2/en not_active Ceased
- 2004-06-04 CA CA2528417A patent/CA2528417C/en not_active Expired - Lifetime
- 2004-06-04 US US10/861,697 patent/US6903820B2/en not_active Expired - Lifetime
- 2004-06-04 US US10/567,185 patent/US7595879B2/en not_active Expired - Lifetime
- 2004-06-04 JP JP2006515173A patent/JP4756218B2/ja not_active Expired - Lifetime
-
2005
- 2005-08-08 US US11/200,498 patent/US7259851B2/en not_active Expired - Lifetime
-
2007
- 2007-08-21 US US11/842,913 patent/US7456965B2/en not_active Expired - Lifetime
-
2008
- 2008-11-25 US US12/323,396 patent/US20090073444A1/en not_active Abandoned
-
2009
- 2009-09-29 US US12/569,835 patent/US7999938B2/en not_active Expired - Lifetime
- 2009-10-02 US US12/572,889 patent/US20100091282A1/en not_active Abandoned
-
2010
- 2010-11-16 US US12/947,823 patent/US20110063616A1/en not_active Abandoned
-
2011
- 2011-08-01 US US13/195,823 patent/US20110285996A1/en not_active Abandoned
-
2012
- 2012-05-25 US US13/481,733 patent/US20130100442A1/en not_active Abandoned
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6501551B1 (en) * | 1991-04-29 | 2002-12-31 | Massachusetts Institute Of Technology | Fiber optic imaging endoscope interferometer with at least one faraday rotator |
| JPH1172431A (ja) * | 1997-08-28 | 1999-03-16 | Olympus Optical Co Ltd | 光断層イメージング装置 |
| JP2000131222A (ja) * | 1998-10-22 | 2000-05-12 | Olympus Optical Co Ltd | 光断層画像装置 |
| US6725073B1 (en) * | 1999-08-17 | 2004-04-20 | Board Of Regents, The University Of Texas System | Methods for noninvasive analyte sensing |
| JP2001066245A (ja) * | 1999-08-26 | 2001-03-16 | Japan Science & Technology Corp | 光波反射断層像観測装置 |
| JP2001241929A (ja) * | 2000-03-01 | 2001-09-07 | Nikon Corp | 非球面形状測定方法、非球面形状測定装置、投影光学系、および露光方法 |
| JP2001330558A (ja) * | 2000-05-25 | 2001-11-30 | Japan Science & Technology Corp | 2次元光ヘテロダイン検出法を用いた光画像計測装置 |
| JP2002013907A (ja) * | 2000-06-30 | 2002-01-18 | Mitsutoyo Corp | 位相シフト干渉縞同時撮像装置における平面形状計測方法 |
| JP2003172690A (ja) * | 2001-12-07 | 2003-06-20 | Olympus Optical Co Ltd | 光イメージング装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20100091282A1 (en) | 2010-04-15 |
| US20110285996A1 (en) | 2011-11-24 |
| US20100014093A1 (en) | 2010-01-21 |
| US7595879B2 (en) | 2009-09-29 |
| US6943881B2 (en) | 2005-09-13 |
| US20050286055A1 (en) | 2005-12-29 |
| JP2006526790A (ja) | 2006-11-24 |
| US20070103683A1 (en) | 2007-05-10 |
| CA2528417A1 (en) | 2005-01-06 |
| US20090073444A1 (en) | 2009-03-19 |
| US20050018202A1 (en) | 2005-01-27 |
| US20130100442A1 (en) | 2013-04-25 |
| US20110063616A1 (en) | 2011-03-17 |
| US6903820B2 (en) | 2005-06-07 |
| US7999938B2 (en) | 2011-08-16 |
| US20040246490A1 (en) | 2004-12-09 |
| WO2005001522A3 (en) | 2005-08-18 |
| US7456965B2 (en) | 2008-11-25 |
| CA2528417C (en) | 2012-09-11 |
| WO2005001522A2 (en) | 2005-01-06 |
| US7259851B2 (en) | 2007-08-21 |
| US20080030740A1 (en) | 2008-02-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4756218B2 (ja) | 光伝搬モードを用いる物質内の光不均質性およびその他特性の測定 | |
| US8498681B2 (en) | Cross-sectional mapping of spectral absorbance features | |
| US7263394B2 (en) | Coherence-gated optical glucose monitor | |
| EP1804661B1 (en) | Integrated disease diagnosis and treatment system | |
| US9134231B2 (en) | Optical measurements of properties in substances using propagation modes of light | |
| EP1639331B1 (en) | Measurements of optical inhomogeneity and other properties in substances using propagation modes of light | |
| US7831298B1 (en) | Mapping physiological functions of tissues in lungs and other organs | |
| US10682061B2 (en) | Photoacoustic remote sensing (PARS) | |
| US7869054B2 (en) | Polarization insensitive multiple probe | |
| KR20060086843A (ko) | 광 전달 모드를 이용한 물질 내의 광학적 불균등성 및 기타특성의 측정 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20070604 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20070604 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20070711 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20100317 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20100615 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20100622 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20100716 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20100726 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20100816 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20100823 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20100916 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20110413 |
|
| RD03 | Notification of appointment of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7423 Effective date: 20110512 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20110512 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20110512 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 4756218 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20140610 Year of fee payment: 3 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |