JP4398728B2 - 埋込み式流体配送装置と埋込み式電極 - Google Patents
埋込み式流体配送装置と埋込み式電極 Download PDFInfo
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- JP4398728B2 JP4398728B2 JP2003537531A JP2003537531A JP4398728B2 JP 4398728 B2 JP4398728 B2 JP 4398728B2 JP 2003537531 A JP2003537531 A JP 2003537531A JP 2003537531 A JP2003537531 A JP 2003537531A JP 4398728 B2 JP4398728 B2 JP 4398728B2
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F11/00—Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
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- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16804—Flow controllers
- A61M5/16813—Flow controllers by controlling the degree of opening of the flow line
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0541—Cochlear electrodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/0208—Subcutaneous access sites for injecting or removing fluids
- A61M2039/0241—Subcutaneous access sites for injecting or removing fluids having means for filtering
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
- A61M2039/025—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body through bones or teeth, e.g. through the skull
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/10—Tube connectors; Tube couplings
- A61M2039/1072—Tube connectors; Tube couplings with a septum present in the connector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/04—General characteristics of the apparatus implanted
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7518—General characteristics of the apparatus with filters bacterial
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0662—Ears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0662—Ears
- A61M2210/0668—Middle ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
- A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
Description
流体の配送は、蝸牛内の位置まで導かれたカテーテルに形成された空洞チャンネル1803を介してなされる。カテーテルに1801には1つ以上の出口1809が含まれる。チャンネル1803は、薬剤を外部に圧送する隔壁を含む内部マイクロポンプ又はポートに接続されてもよい。カテーテル1801の中心近く、又は、カテーテル1801の中心から縁の方へずれた位置に配設された空洞チャンネル1803はリバースモールディングによって成形される。これは、射出成形の前に、型に位置ホルダが含まれてもよいことを意味する。射出成形の後に位置ホルダは次に取り外され、空洞チャンネルはその位置に残される。流体配送チャネルの出口1809は基端及び/又は遠位端に位置されてもよい。流体配送のための出口1809は、時間経過に伴う組織の成長や出口の閉塞を防ぐために緩効性生物活性剤のリングでコーティングされてもよい。
Claims (21)
- 移植蝸牛刺激システムであって、
電極リード、
電極接触子と電極接触子の近くに1つ以上の流体出口を含む電極アレイ;
電極リード及び電極アレイに形成され、電極リード及び電極アレイを通して流体の搬送を可能にする流体搬送チャネルであり、流体出口に流体連通する流体搬送チャネル;及び
電極リードの流体搬送チャネルに隣接し取り付けられる埋込み可能なハウジングであり、電極接触子に送られる電流パルスを発生させる電子装置を含む埋込み可能なハウジング、
を含んでなる前記移植蝸牛刺激システム。 - 請求項1に記載の移植蝸牛刺激システムであり、電極リードの流体搬送チャネルに流体連通するマイクロ隔壁コネクタをさらに含み、前記マイクロ隔壁コネクタは、
隔壁を有する埋込み可能なポートコネクタ、及び
前記隔壁に挿入する針を有する埋込み可能なスピアコネクタを、
含んでなる、
前記移植蝸牛刺激システム。 - 請求項2に記載の移植蝸牛刺激システムであって、
前記埋込み可能なポートコネクタは、
前記針と流体連通する流体源、
前記隔壁に圧力をかける圧力リング、及び
前記針が前記隔壁に挿入されるときに前記針を案内する機構とを、
含んでなる、
前記移植蝸牛刺激システム。 - 請求項2に記載の移植蝸牛刺激システムであって、
前記埋込み可能なポートコネクタと前記埋込み可能なスピアコネクタが直接接触することを防ぐ停止装置、及び
前記隔壁から前記針が離脱することを防ぐロック装置
をさらに含んでなる、
前記移植蝸牛刺激システム。 - 請求項2に記載の移植蝸牛刺激システムであって、
前記埋込み可能なポートコネクタに流体連通するポートカテーテルをさらに含
んでなる、前記移植蝸牛刺激システム。 - 請求項5に記載の移植蝸牛刺激システムであって、前記埋込み可能なポートコ
ネクタは針と流体連通する流体源を含み、前記システムは前記流体源と前記ポ
ートカテーテルの間に配設された細菌ろ過器をさらに含んでなる、
前記移植蝸牛刺激システム。 - 請求項5に記載の移植蝸牛刺激システムであって、前記埋込み可能なポートコ
ネクタと前記ポートカテーテルの間に配設された細菌ろ過器をさらに含んでな
る、前記移植蝸牛刺激システム。 - 請求項2に記載の移植蝸牛刺激システムであって、前記針に流体連通するスピ
アカテーテルをさらに含んでなる前記移植蝸牛刺激システム。 - 請求項1に記載の移植蝸牛刺激システムであって、
埋込み可能な流体源、
前記流体源に流体連通する第1カテーテル、及び
前記電極リードの流体搬送チャネルと流体連通するマイクロ隔壁コネクタをさらに含んでなり、前記マイクロ隔壁コネクタは
前記第1カテーテルに連通し、かつ針を有する埋込み可能なスピアコネクタ、及び
前記針を挿入する隔壁を有する埋込み可能なポートコネクタを
含む、マイクロ隔壁コネクタ、
を含んでなる前記移植蝸牛刺激システム。 - 前記埋込み可能なポートコネクタに流体連通する第2カテーテ
ルをさらに含んでなる、請求項9に記載の移植蝸牛刺激システム。 - 前記流体源は液体ポンプである請求項9に記載の移植蝸牛刺激
システム。 - 前記流体源はリザーバである請求項9に記載の移植蝸牛刺激シ
ステム。 - 請求項1に記載の移植蝸牛刺激システムであって、
流体源に流体連通する第1カテーテルと、
マイクロ隔壁コネクタであり、
前記第1カテーテルに連通する埋込み可能なスピアコネクタを含み、前記埋込み可能なスピアコネクタは針を含み、及び
該針を挿入する隔壁を有する埋込み可能なポートコネクタを含んでなる、マイクロ隔壁コネクタ、及び
前記埋込み可能なポートコネクタに流体連通し、及び電極リードの流体搬送チャネルに流体連通する第2カテーテル
をさらに含んで成る、前記移植蝸牛刺激システム。 - 請求項1に記載の移植蝸牛刺激システムであって、
流体源に流体連通する第1カテーテル、
電極リードの流体搬送チャネルに流体連通するマイクロ隔壁コネクタであって、
マイクロ隔壁コネクタは、
前記第1カテーテルに連通する埋込み可能なスピアコネクタを含み、前記埋込み可能なスピアコネクタは針を含み、及び
該針を挿入する隔壁を有する埋込み可能なポートコネクタを含んでなる、マイクロ隔壁コネクタ、及び
前記埋込み可能なポートコネクタを対象の内耳に取り付けるための固定装置を、
さらに含んでなる移植蝸牛刺激システム。 - 前記埋込み可能なポートコネクタに流体連通する第2カテーテ
ルをさらに含んでなる、請求項14に記載の移植蝸牛刺激システム。 - 前記固定装置は前記対象の岬角骨に付けられる請求項14に記
載の移植蝸牛刺激システム。 - 請求項1に記載の移植蝸牛刺激システムであって、
第1隔壁を含む埋込み可能な流体リザーバと、
前記埋込み可能な流体リザーバに流体連通するカテーテルと、
前記カテーテルに流体連通する第1針とを、
さらに含んでなる前記移植蝸牛刺激システム。 - 前記埋込み可能な流体リザーバと前記カテーテルの間に配設された細菌ろ過器をさらに含んでなる請求項17に記載の移植蝸牛刺激システム。
- 前記埋込み可能な流体リザーバと前記カテーテルの間に配設された流れ拘束器をさらに含んでなる請求項17に記載の移植蝸牛刺激システム。
- 前記第1針を前記カテーテルに取り付けるためのアンカーをさらに含んでなる請求項17に記載の移植蝸牛刺激システム。
- 前記第1針に流体連通するアクセスポートをさらに含んでなる請求項17に記載の移植蝸牛刺激システムであって、前記アクセスポートは、マイクロリザーバを含む第2隔壁と、前記マイクロリザーバに流体連通する第2針とを含んでなる移植蝸牛刺激システム。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
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US33645201P | 2001-10-24 | 2001-10-24 | |
US39442702P | 2002-07-08 | 2002-07-08 | |
US39460202P | 2002-07-09 | 2002-07-09 | |
US41770402P | 2002-10-10 | 2002-10-10 | |
PCT/IB2002/004731 WO2003034960A1 (en) | 2001-10-24 | 2002-10-24 | Implantable fluid delivery apparatuses and implantable electrode |
Publications (2)
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JP2005506148A JP2005506148A (ja) | 2005-03-03 |
JP4398728B2 true JP4398728B2 (ja) | 2010-01-13 |
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JP2003537531A Expired - Lifetime JP4398728B2 (ja) | 2001-10-24 | 2002-10-24 | 埋込み式流体配送装置と埋込み式電極 |
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Country | Link |
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US (6) | US7044942B2 (ja) |
EP (3) | EP2226043B1 (ja) |
JP (1) | JP4398728B2 (ja) |
AU (3) | AU2002363103B2 (ja) |
CA (1) | CA2460676C (ja) |
WO (1) | WO2003034960A1 (ja) |
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AUPR148400A0 (en) | 2000-11-14 | 2000-12-07 | Cochlear Limited | Apparatus for delivery of pharmaceuticals to the cochlea |
US9089450B2 (en) * | 2000-11-14 | 2015-07-28 | Cochlear Limited | Implantatable component having an accessible lumen and a drug release capsule for introduction into same |
US7702394B2 (en) | 2001-05-01 | 2010-04-20 | Intrapace, Inc. | Responsive gastric stimulator |
AU2002363103B2 (en) | 2001-10-24 | 2008-10-16 | Med-El Elektromedizinische Gerate Ges.M.B.H. | Implantable fluid delivery apparatuses and implantable electrode |
US20070088335A1 (en) * | 2001-10-24 | 2007-04-19 | Med-El Elektromedizinische Geraete Gmbh | Implantable neuro-stimulation electrode with fluid reservoir |
AUPR879201A0 (en) * | 2001-11-09 | 2001-12-06 | Cochlear Limited | Subthreshold stimulation of a cochlea |
US20100030130A1 (en) * | 2001-11-09 | 2010-02-04 | Cochlear Limited | Pharmaceutical intervention for modulation of neural plasticity |
AUPS081502A0 (en) * | 2002-02-28 | 2002-03-21 | Cochlear Limited | Connector for drug delivery system |
US7009502B2 (en) | 2002-08-26 | 2006-03-07 | Automotive Technologies International, Inc. | Method for controlling output of a classification algorithm |
WO2004026199A2 (en) * | 2002-09-19 | 2004-04-01 | Advanced Bionics Corporation | Cochlear implant electrode and method of making same |
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- 2002-10-24 JP JP2003537531A patent/JP4398728B2/ja not_active Expired - Lifetime
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- 2002-10-24 WO PCT/IB2002/004731 patent/WO2003034960A1/en active Application Filing
- 2002-10-24 EP EP02801986.7A patent/EP1441679B8/en not_active Expired - Lifetime
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AU2009200181B2 (en) | 2010-03-04 |
CA2460676A1 (en) | 2003-05-01 |
US20110034857A1 (en) | 2011-02-10 |
EP1441679B8 (en) | 2018-05-30 |
US10272232B2 (en) | 2019-04-30 |
EP2226043A1 (en) | 2010-09-08 |
WO2003034960A1 (en) | 2003-05-01 |
AU2009200181A1 (en) | 2009-02-12 |
US20170028182A1 (en) | 2017-02-02 |
EP1441679A1 (en) | 2004-08-04 |
AU2002363103B2 (en) | 2008-10-16 |
JP2005506148A (ja) | 2005-03-03 |
US9498608B2 (en) | 2016-11-22 |
EP2226043B1 (en) | 2014-12-31 |
EP2221030A1 (en) | 2010-08-25 |
EP1441679B1 (en) | 2018-04-04 |
AU2010202239A1 (en) | 2010-06-24 |
US20060184143A1 (en) | 2006-08-17 |
US9550051B2 (en) | 2017-01-24 |
US7815615B2 (en) | 2010-10-19 |
AU2010202239B2 (en) | 2013-01-24 |
US20160220797A1 (en) | 2016-08-04 |
US20030097121A1 (en) | 2003-05-22 |
CA2460676C (en) | 2010-03-23 |
US20150025509A1 (en) | 2015-01-22 |
US7044942B2 (en) | 2006-05-16 |
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