JP4225814B2 - Caffeine-containing catechin composition decaffeination method - Google Patents

Caffeine-containing catechin composition decaffeination method Download PDF

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JP4225814B2
JP4225814B2 JP2003086895A JP2003086895A JP4225814B2 JP 4225814 B2 JP4225814 B2 JP 4225814B2 JP 2003086895 A JP2003086895 A JP 2003086895A JP 2003086895 A JP2003086895 A JP 2003086895A JP 4225814 B2 JP4225814 B2 JP 4225814B2
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Prior art keywords
caffeine
weight
catechin
composition
clay
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JP2004222719A (en
Inventor
敦 小西
枝里 板屋
宏和 高橋
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花王株式会社
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Priority claimed from CN2006101695003A external-priority patent/CN1981586B/en
Priority claimed from AU2003275679A external-priority patent/AU2003275679A1/en
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Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a method for selectively removing caffeine from a caffeine-containing catechin composition.
[0002]
[Prior art]
Catechins are known to have an action to suppress cholesterol elevation, an action to inhibit α-amylase activity, and the like (see, for example, Patent Document 1 and Patent Document 2). In order to develop such physiological effects of catechins, it is necessary to drink 4-5 cups of tea per day for adults. For this reason, the technique of mix | blending catechins with high concentration in a drink is desired so that a large amount of catechins can be ingested more simply.
[0003]
However, although about 15% of catechins are contained in tea leaves, caffeine components are usually contained in 2-4%. Since caffeine exhibits central nervous excitability, it is used to suppress drowsiness, but it is also said to cause harmful effects such as irritability, nausea and insomnia due to excessive intake. For this reason, methods for selectively removing only caffeine from caffeine-containing compositions have been studied.
[0004]
For example, as a method for decaffeination of coffee, a method in which coffee is brought into contact with a caffeine adsorbent such as activated carbon at 120 to 250 atmospheres (Patent Document 3), or an aqueous solution containing caffeine as an active clay or acidic clay. There has been proposed a method (Patent Document 4) in which caffeine is selectively removed by contact.
[0005]
However, the former relates to the supercritical extraction technology, and the process equipment load is excessive, and lacks simplicity in implementation at the industrial level. In addition, this method has a problem that not only caffeine is selectively removed, but also the composition of catechins as active ingredients is changed. On the other hand, the latter method can selectively remove caffeine simply by using activated clay or acidic clay, but has a problem that the hue may deteriorate.
[0006]
[Patent Document 1]
JP-A-60-156614 [Patent Document 2]
Japanese Patent Laid-Open No. 3-133828 [Patent Document 3]
JP-A-53-18772 [Patent Document 4]
JP-A-6-142405 gazette
[Problems to be solved by the invention]
An object of the present invention is to provide a method for selectively removing caffeine in a caffeine-containing catechin composition without significantly changing the catechin composition and without deteriorating the hue.
[0008]
[Means for Solving the Problems]
The present inventor made catechin contact with activated carbon and acidic clay or activated clay in a state where caffeine contained in the catechin composition was dissolved in a mixed solution of a specific ratio of water and an organic solvent. The present inventors have found that caffeine can be selectively removed without significantly changing the composition and without deteriorating the hue. Furthermore, it has also been found that the tea extract thus obtained contains catechins and has good hue and stability, and is useful as a beverage or a beverage ingredient.
[0009]
The present invention is characterized in that a caffeine-containing catechin composition is dissolved in a mixed solution having an organic solvent / water weight ratio of 9/1 to 1/9 and brought into contact with activated carbon and acidic clay or activated clay. The present invention provides a method for selectively removing caffeine from a caffeine-containing catechin composition.
[0010]
The present invention also provides a mixed solution of a caffeine-containing catechin composition containing 25 to 90% by weight of non-polymer catechins in a solid content, wherein the organic solvent / water weight ratio is 9/1 to 1/9. And a method for producing a green tea extract, which comprises selectively dissolving caffeine by contact with activated carbon and acid clay or activated clay.
[0011]
The present invention also provides:
(A) The ratio of the gallate body in non-polymer catechins is 45 to 60% by weight,
(B) The weight ratio of non-polymer catechins / caffeine is 8 to 40,
(C) the weight ratio of non-polymer catechins / (sucrose + glucose) is 2-15,
(D) The present invention provides a caffeine-containing tea extract having a dietary fiber in a solid content of 0.5% by weight or less.
[0012]
DETAILED DESCRIPTION OF THE INVENTION
The caffeine-containing catechin composition used in the present invention contains at least one non-polymer catechin. Non-polymer catechins include non-epimeric catechins such as catechin, gallocatechin, catechin gallate, gallocatechin gallate, and epicatechins such as epicatechin, epigallocatechin, epicatechin gallate, epigallocatechin gallate, etc. It is a general term.
[0013]
Examples of the caffeine-containing catechin composition containing such non-polymer catechins include extracts obtained from tea leaves such as green tea, black tea, and oolong tea. Other caffeine-containing plant origins such as a mixture of caffeine such as coffee and tea extract can also be used.
[0014]
More specifically, the tea leaves used here include tea leaves made from tea leaves obtained from the genus Camellia, for example, C. sinensis, C. assamica, and Yabuki species, or hybrids thereof. The tea leaves produced include green teas such as sencha, bancha, gyokuro, tencha, and kettle roasted tea.
Extraction of a caffeine-containing catechin composition from tea leaves can be performed by a method such as stirring extraction. At the time of extraction, an organic acid or an organic acid salt such as sodium ascorbate may be added to water in advance. Moreover, you may use together the method of extracting in so-called non-oxidative atmosphere, ventilating inert gas, such as boiling deaeration and nitrogen gas, and removing dissolved oxygen.
[0015]
Instead of extracting from tea leaves, a concentrate of tea extract may be used by dissolving or diluting in water, or an extract from tea leaves and a concentrate of tea extract may be used in combination.
Here, the concentrate of tea extract is obtained by concentrating an extract extracted from tea leaves with hot water or a water-soluble organic solvent. For example, JP-A-59-219384 and JP-A-4-20589. No. 5, 260-907, JP-A-5-306279, and the like.
As the raw material caffeine-containing catechins composition, a green tea extract containing 25 to 90% by weight, particularly 25 to 70% by weight, and further 25 to 40% by weight of non-polymer catechins in the solid content is used. However, it is preferable because taste components other than non-polymer catechins remain. Here, the solid content means the weight of the caffeine-containing catechin composition obtained when the caffeine-containing catechin composition is dried and solidified.
[0016]
Specifically, commercially available crude catechin preparations such as “Polyphenone” manufactured by Tokyo Food Techno Co., “Theafuran” manufactured by ITO EN Co., Ltd., “Sunphenon” manufactured by Taiyo Kagaku Co., Ltd. may be used.
[0017]
Examples of the organic solvent used in the present invention include ethanol, methanol, acetone, and ethyl acetate. Of these, hydrophilic organic solvents such as ethanol, methanol, and acetone are preferable, and ethanol is particularly preferable in consideration of use in foods.
[0018]
In the present invention, it is necessary to adjust the weight ratio of the organic solvent / water to the range of 9/1 to 1/9, preferably 9/1 to 5/5, more preferably 8/2 to 6/4. is there. When the ratio of the organic solvent exceeds 9/1, the extraction efficiency of catechins decreases, and when it is less than 1/9, the effect of improving the taste of the decaffeinated product becomes insufficient.
[0019]
The method for dissolving the caffeine-containing catechin composition in a mixed solution of an organic solvent and water is not particularly limited, and by dissolving the caffeine-containing catechin composition in water and then adding the organic solvent / The weight ratio of water may be in the range of 9/1 to 1/9. After the caffeine-containing catechin composition is suspended in an organic solvent, water may be gradually added to obtain a similar ratio. From the viewpoint of extraction efficiency, a method of adding an organic solvent after dissolving in water is preferable. In the treatment of a caffeine-containing catechin composition, catechins are adsorbed on activated carbon and acidic clay or activated clay when treated with water alone, whereas this influence can be eliminated in the presence of an organic solvent.
[0020]
In the present invention, the caffeine-containing catechin is treated by adding 10 to 40 parts by weight, particularly 15 to 30 parts by weight of the caffeine-containing catechin composition to 100 parts by weight of the mixed solution of the organic solvent and water. This is preferable because the composition can be processed efficiently.
[0021]
It is preferable that the required amount of water or organic solvent is slowly added dropwise over a period of about 10 to 30 minutes. Moreover, in order to raise the extraction efficiency of catechins, it is preferable to add dropwise with stirring. It is more preferable to provide an aging time of about 10 to 120 minutes after the completion of the dropwise addition of water.
These treatments can be carried out at 10 to 60 ° C., preferably 10 to 50 ° C., more preferably 10 to 40 ° C.
[0022]
The activated carbon used in the present invention is not particularly limited as long as it is generally used at an industrial level. For example, ZN-50 (manufactured by Hokuetsu Carbon Co., Ltd.), Kuraray Coal GLC, Kuraray Coal PK-D, Kuraray Coal PW Commercially available products such as -D (manufactured by Kuraray Chemical Co., Ltd.), white birch AW50, white birch A, white birch M, white birch C (manufactured by Takeda Pharmaceutical Company Limited) can be used.
The pore volume of the activated carbon is preferably 0.01 to 0.8 mL / g, particularly preferably 0.1 to 0.7 mL / g. The specific surface area is preferably in the range of 800 to 1300 m 2 / g, particularly 900 to 1200 m 2 / g. These physical property values are values based on the nitrogen adsorption method.
[0023]
Activated carbon is preferably added in an amount of 0.5 to 5 parts by weight, particularly 0.5 to 3 parts by weight, based on 100 parts by weight of a mixed solution of an organic solvent and water. If the amount of activated carbon added is too small, the caffeine removal efficiency will deteriorate, and if it is too large, the cake resistance in the filtration step will increase, which is not preferable.
[0024]
The acid clay or activated clay used in the present invention contains SiO 2 , Al 2 O 3 , Fe 2 O 3 , CaO, MgO, etc. as general chemical components, but SiO 2 / Al 2 O. 3 The ratio is preferably 3-12, especially 4-9. A composition containing 2 to 5% by weight of Fe 2 O 3 , 0 to 1.5% by weight of CaO and 1 to 7% by weight of MgO is preferable.
Activated clay is a naturally occurring acidic clay (montmorillonite clay) treated with a mineral acid such as sulfuric acid, and is a compound having a porous structure having a large specific surface area and adsorption capacity. It is known that when acid clay is further acid-treated, the specific surface area is changed to improve the decolorization ability and change physical properties.
[0025]
The specific surface area of the acid clay or the activated clay varies depending on the degree of acid treatment, etc., but is preferably 50 to 350 m 2 / g, and the pH (5% suspension) is 2.5 to 8, particularly 3.6 to 7. Are preferred. For example, as the acid clay, commercially available products such as Mizuka Ace # 600 (manufactured by Mizusawa Chemical Co., Ltd.) can be used.
[0026]
The acid clay or activated clay is preferably added in an amount of 2.5 to 25 parts by weight, particularly 2.5 to 15 parts by weight, based on 100 parts by weight of a mixed solution of an organic solvent and water. If the amount of acid clay or activated clay added is too small, the caffeine removal efficiency will deteriorate, and if too much, the cake resistance in the filtration step will increase, which is not preferable.
[0027]
Moreover, it is preferable that the ratio of activated carbon and acid clay or activated clay is 1-10 with respect to activated carbon 1 by weight ratio, and especially activated carbon: acid clay or activated clay = 1: 1 to 1: 6. Is preferred.
Furthermore, when contacting with a caffeine-containing catechin composition, activated carbon and acid clay or activated clay may be contacted at the same time, or may be contacted one by one (the order is not limited).
[0028]
The contact treatment between the caffeine-containing catechin composition and the activated carbon and the acid clay or activated clay may be performed by any method such as a batch method or a continuous treatment using a column. In general, powdered activated carbon or the like is added and stirred, and after selectively adsorbing caffeine, it is continuously obtained using a method of obtaining a filtrate from which caffeine has been removed by filtration, or a column packed with granular activated carbon or the like. A method of selectively adsorbing caffeine by treatment is employed.
The solution containing the catechin composition after being brought into contact with the activated carbon and the acid clay or the activated clay is distilled off using a method such as vacuum distillation to remove the organic solvent from the system. The catechins composition after treatment may be either liquid or solid, but when prepared as a solid, it may be pulverized by a method such as freeze drying or spray drying.
[0029]
It is preferable that the composition of the non-polymer catechins contained in the catechin composition after the decaffeination treatment according to the present invention is essentially unchanged from that before the treatment. The yield of the non-polymer catechins in the mixed solution of the organic solvent and water before and after the treatment is preferably 70% by weight or more, particularly preferably 80% by weight or more. Therefore, the non-polymer catechin content in the composition after the decaffeination treatment is preferably 80 to 95% by weight, particularly 85 to 95% by weight, and more preferably 90 to 95% by weight in the solid content.
[0030]
In addition, the non-polymer catechins in the catechin composition after the decaffeination treatment according to the present invention are epigallocatechin gallate, gallocatechin gallate, gallo body composed of epigallocatechin and gallocatechin, and epicatechin gallate It is preferable that the ratio of the non-gallo body consisting of catechin gallate, epicatechin and catechin maintain the composition of natural green tea leaves. That is, it is preferable that the total amount of the four types of galloforms always exceeds the total amount of the four types of non-galloforms in that the composition of natural green tea leaves is maintained even in the purified product.
[0031]
The caffeine concentration in the catechin composition after decaffeination treatment according to the present invention is such that the weight ratio of non-polymer catechins / caffeine is 7 to 60, more preferably 7 to 50 with respect to the non-polymer catechins. In particular, it is preferably 8 to 40.
Further, the proportion of gallate bodies composed of catechin gallate, epicatechin gallate, gallocatechin gallate and epigallocatechin gallate in the catechin gallate composition after decaffeination treatment according to the present invention is 45 wt. % Or more, particularly 45 to 60% by weight, is preferable in view of the effectiveness of physiological effects of non-polymer catechins.
[0032]
The weight ratio of non-polymer catechins / (sucrose + glucose) in the catechin composition after decaffeination is preferably 2-15, more preferably 2-10, even more preferably 2-8, and 3-7. Particularly preferred. If the ratio exceeds 15, there is a problem with the flavor of the tea extract. On the other hand, a tea extract with a ratio of less than 2 is not preferred because it contains too much sugar. The dietary fiber in the solid content of the catechin composition after decaffeination treatment is 0.5% by weight or less, preferably not contained because of the ease of transfer of non-polymer catechins into the body. .
[0033]
【Example】
Measurement of catechins After diluting a catechin composition with distilled water and filtering with a filter (0.8 μm), using a high performance liquid chromatograph (model SCL-10AVP) manufactured by Shimadzu Corporation, for an octadecyl group-introduced liquid chromatograph Packed column L-column TM ODS (4.6 mmφ × 250 mm: manufactured by Chemical Substances Evaluation and Research Institute) was attached, and the column temperature was 35 ° C. and the gradient method using liquid A and liquid B was performed. The mobile phase A solution was a distilled aqueous solution containing 0.1 mol / L of acetic acid, the B solution was an acetonitrile solution containing 0.1 mol / L of acetic acid, the sample injection amount was 20 μL, and the UV detector wavelength was 280 nm. .
[0034]
Measurement of caffeine (analytical instrument)
Uses HPLC (Hitachi, Ltd.) equipment.
Plotter: D-2500, Detector: L-4200
Pump: L-7100, Autosampler: L-7200
Column: lnertsil ODS-2, inner diameter 2.1 mm x length 250 mm
(Analysis conditions)
Sample injection volume: 10 μL, flow rate: 1.0 mL / min
UV absorption photometer detection wavelength: 280nm
Eluent A: 0.1M acetic acid aqueous solution, eluent B: 0.1M acetic acid acetonitrile solution
From the area% obtained here, the weight% was obtained from the standard substance.
[0035]
Hue evaluation (absorbance)
(Analytical equipment)
UV MINI1240 (manufactured by Shimadzu Corporation) apparatus is used.
The value at an absorbance of 450 nm was measured with a spectrophotometer. In the measurement, the purified catechin composition was diluted with ion-exchanged water so that the concentration of catechin was 100 mg%, and the absorbance was measured using the sample to obtain a hue index.
[0036]
Visual evaluation of stability The purified catechin composition was diluted with ion-exchanged water so that the catechin concentration was 100 mg%, and the evaluation sample contained in the 50 mL vial was observed on the illuminator. Visual judgment was made.
[0037]
Examples 1-2 and Comparative Examples 1-2
Under the conditions shown in Table 1, caffeine was removed from the caffeine-containing catechin composition.
The caffeine-containing catechin composition used (Polyphenone HG, manufactured by Tokyo Food Techno Co., Ltd.) has a non-polymer catechin content of 33.70% by weight, a caffeine content of 5.5% by weight, and a non-polymer catechin. Class / caffeine = 6.1, gallate body ratio 50.7% by weight.
[0038]
(Example 1 treatment method)
100 g of caffeine-containing catechin composition (Polyphenone HG, manufactured by Tokyo Food Techno Co., Ltd.) was suspended in 490.9 g of 95% ethanol aqueous solution under normal temperature and 250 rpm stirring conditions, and activated carbon (Kuraray Coal GLC, manufactured by Kuraray Chemical Co., Ltd.) After adding 20 g and 100 g of acid clay (Mizuka Ace # 600, manufactured by Mizusawa Chemical Co., Ltd.), stirring was continued for about 10 minutes. Then, 409.1 g of 40% ethanol aqueous solution was dropped over 10 minutes, and then the stirring treatment was continued for about 30 minutes at room temperature. Thereafter, the activated carbon and the precipitate were filtered with No. 2 filter paper, and then re-filtered with a 0.2 μm membrane filter. Finally, 200 g of ion-exchanged water was added to the filtrate, and ethanol was distilled off at 40 ° C. and 25 Torr to obtain a product.
[0039]
(Example 2 treatment method)
300 g of a caffeine-containing catechin composition (Polyphenone HG, manufactured by Tokyo Food Techno Co., Ltd.) was suspended in 630 g of a 47.5% ethanol aqueous solution at room temperature and 250 rpm stirring condition, dissolved for 20 minutes, and then 570 g of a 95% ethanol aqueous solution was added to 20 g. Added dropwise over a period of minutes. Next, 30 g of acid clay (Mizuka Ace # 600, manufactured by Mizusawa Chemical Co., Ltd.) was added and stirring was continued for 2 hours. Thereafter, the acid clay and precipitate were filtered with No. 2 filter paper. Next, 30 g of activated carbon (Kuraray Coal GLC, manufactured by Kuraray Chemical Co., Ltd.) was added to the filtrate and stirred for 2 hours. Thereafter, the activated carbon was filtered with No. 2 filter paper and re-filtered with a 0.2 μm membrane filter. Finally, 230 g of ion-exchanged water was added to the filtrate, and ethanol was distilled off at 40 ° C. and 25 Torr to obtain a product.
[0040]
(Comparative Example 1 treatment method)
100 g of caffeine-containing catechin composition (Polyphenone HG, manufactured by Tokyo Food Techno Co., Ltd.) is suspended in 900 g of water under stirring at room temperature and 250 rpm, and 100 g of acid clay (Mizuka Ace # 600, manufactured by Mizusawa Chemical Co., Ltd.) is added. The stirring was continued for about 20 minutes. Thereafter, the stirring process was continued for about 30 minutes at room temperature. Next, after filtering with No. 2 filter paper, it re-filtered with the 0.2 micrometer membrane filter. Finally, the water was gradually evaporated with a drier until the water content was the same as in Example 1 to obtain a product.
[0041]
(Comparative Example 2 treatment method)
100 g of a caffeine-containing catechin composition (polyphenone HG, manufactured by Tokyo Food Techno Co., Ltd.) is suspended in 900 g of water at room temperature and 250 rpm under stirring, and 20 g of activated carbon (Kuraray Coal GLC, manufactured by Kuraray Chemical Co., Ltd.) and acid clay ( After introducing 100 g of Mizuka Ace # 600 (manufactured by Mizusawa Chemical Co., Ltd.), stirring was continued for about 20 minutes. Thereafter, the stirring process was continued for about 30 minutes at room temperature. Next, after filtering with No. 2 filter paper, it re-filtered with the 0.2 micrometer membrane filter. Finally, the water was gradually evaporated with a drier until the water content was the same as in Example 1 to obtain a product.
[0042]
[Table 1]
[0043]
As is apparent from the results in Table 1, by treating a caffeine-containing catechin composition according to the present invention, catechins that are selectively removed and have improved hues while maintaining the catechin composition. A composition can be obtained.
[0044]
Example 3
Caffeine-containing catechins composition (polyphenone HG, manufactured by Tokyo Food Techno Co., Ltd .: non-polymer catechins content 33.70% by weight, caffeine content 5.5% by weight, non-polymer catechins / caffeine = 6 1 and 12.8 kg of gallate body ratio 50.7% by weight) are dissolved in 13.44 kg of deionized water. Next, 13.44 kg of 95% ethanol was added and mixed and stirred. Next, 95% ethanol was similarly mixed at a dropping rate of 22 kg / hr to perform extraction. 2 kg of acid clay was added to 64 kg of the extract obtained after 30 minutes of extraction, and the clay was treated. After the clay treatment, solid-liquid separation was performed by filtration. Activated carbon treatment was performed by adding 1 kg of activated carbon to the clay-treated filtrate thus obtained. After the activated carbon treatment, filtration was performed to collect the filtrate. The obtained filtrate was concentrated to remove ethanol, and then the solid content concentration was adjusted with deionized water to obtain a predetermined product.
[0045]
[Table 2]
[0046]
【The invention's effect】
According to the present invention, caffeine in a caffeine-containing catechin composition can be selectively removed without significantly changing the catechin composition and without deteriorating the hue.

Claims (6)

  1.   A caffeine-containing catechin composition, wherein a caffeine-containing catechin composition is dissolved in a mixed solution having a weight ratio of ethanol / water of 9/1 to 6/4 and contacted with activated carbon and acidic clay. How to selectively remove caffeine from.
  2.   The method according to claim 1, wherein the caffeine-containing catechin composition is a green tea extract containing 25 to 90% by weight of non-polymer catechins in the solid content.
  3.   The method according to claim 1 or 2, wherein the weight ratio of non-polymerized catechins / caffeine in the caffeine-containing catechin composition after caffeine removal treatment is 7 to 60.
  4.   A caffeine-containing green tea extract containing 25 to 90% by weight of non-polymer catechins in a solid content is dissolved in a mixed solution having an ethanol / water weight ratio of 9/1 to 6/4, and activated carbon and acid clay. A method for producing a green tea extract, wherein the weight ratio of non-polymer catechins / caffeine is 7 to 60, characterized in that the green tea extract is brought into contact with the mixture.
  5. The production method according to claim 4 , wherein the weight ratio of non-polymer catechins / caffeine in the obtained green tea extract is 8 to 40 .
  6. Obtained by the method of claim 5,
    (A) The ratio of the gallate body in non-polymer catechins is 45 to 60% by weight,
    (B) The weight ratio of non-polymer catechins / caffeine is 8 to 40,
    (C) the weight ratio of non-polymer catechins / (sucrose + glucose) is 2-15,
    (D) Green tea extract whose dietary fiber in solid content is 0.5 wt% or less.
JP2003086895A 2002-11-29 2003-03-27 Caffeine-containing catechin composition decaffeination method Expired - Fee Related JP4225814B2 (en)

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Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
JP2003086895A JP4225814B2 (en) 2002-11-29 2003-03-27 Caffeine-containing catechin composition decaffeination method
AU2003275679A AU2003275679A1 (en) 2002-10-28 2003-10-27 Method of removing caffeine from caffeine-containing catechin compound composition
PCT/JP2003/013700 WO2004037022A1 (en) 2002-10-28 2003-10-27 Method of removing caffeine from caffeine-containing catechin compound composition
EP03758933.0A EP1557097B1 (en) 2002-10-28 2003-10-27 Method of removing caffeine from caffeine-containing catechin compound composition
KR1020057005930A KR101049391B1 (en) 2002-10-28 2003-10-27 Decaffeine Method of Caffeine-Containing Catechin Compositions
US10/532,727 US7883734B2 (en) 2002-10-28 2003-10-27 Method of removing caffeine from caffeine-containing catechin compound composition
EP13178703.8A EP2659791B1 (en) 2002-10-28 2003-10-27 Caffeine-containing catechin compound composition
CN2006101695003A CN1981586B (en) 2002-10-28 2003-10-27 Method for purifying condensate of tea extraction compound
EP11173763.1A EP2382877B8 (en) 2002-10-28 2003-10-27 Green tea extract
EP11173762.3A EP2382876B1 (en) 2002-10-28 2003-10-27 Method of purifying a solid concentrate of a tea extract.
TW099122034A TWI365048B (en) 2002-10-28 2003-10-28
TW092129912A TWI344822B (en) 2002-10-28 2003-10-28
US12/971,555 US8574655B2 (en) 2002-10-28 2010-12-17 Packaged beverage with caffeine-containing catechin composition
US14/029,259 US9198946B2 (en) 2002-10-28 2013-09-17 Green tea extract

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JP5162594B2 (en) 2007-09-05 2013-03-13 花王株式会社 Method for producing purified tea extract
US20110223310A1 (en) * 2008-11-21 2011-09-15 Kao Corporation Purified green tea extract
JP4951109B2 (en) * 2010-10-08 2012-06-13 花王株式会社 Method for producing decaffeinated green coffee bean extract
JP6338845B2 (en) * 2013-11-15 2018-06-06 キリンビバレッジ株式会社 Method for producing tea beverage or coffee beverage
US20200238251A1 (en) 2017-09-05 2020-07-30 National Institute For Materials Science Purine base adsorption material, purine base adsorption filter using the same, purine base adsorption column filler, and purine base removal system using the same
TW202037274A (en) 2018-12-06 2020-10-16 日商花王股份有限公司 Powdered green tea extract composition

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