JP3648569B2 - Method for supplying and using aqueous solution for disinfection or disinfection purposes - Google Patents
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Description
技術分野
本発明は、生物を扱う実験室等における種々の器具や作業者の手の殺菌や、病院用における消毒、植物栽培等における消毒等の、医療、食品工業、飲食業、獣医、畜産業、衛生を要する公共的な場所や、殺菌消毒を要する場所等で用いる殺菌剤として使用する殺菌性、抗菌性等の消毒効果を有する酸性水溶液の新規な供給方法またはその使用方法に関する。
従来技術
除菌または消毒目的に使用される酸性水溶液として電解水が知られているが、従来このような電解水は、最低限でも電解用直流電源装置、アノード、カソード及び両電極の間に隔膜を有し、アノード室とカソード室とに分離された電解槽、原水導入管から供給される原水と、塩化ナトリウム水溶液添加手段から供給される塩化ナトリウム水溶液とを混合して成る被電解水を、該アノード室とカソード室に供給する導入管、該アノード室とカソード室のそれぞれから生成水を取り出す導出管、該アノード室から取り出された生成水と、該原水導入管から分岐させた希釈用原水導入管から供給される原水及び／または前記カソード室から取り出される生成水とを混合希釈する手段と有する電解水製造装置から製造されていた。
また、特開平４−９４７８５号公報には、カソードとアノードの両電極間に隔膜を有しない電解槽の一方に、原水と、塩化ナトリウム水溶液添加手段から供給される塩化ナトリウム水溶液と、塩酸水溶液添加手段から供給される塩酸水溶液とを混合して成る被電解水の供給導入管を接続し、該電解槽の他方に電解生成水を取り出す導出管を設け、上記の電解生成水と原水が混合可能になるように該原水導入管と該電解生成水導出管とを接続してなる電解水製造装置が記載されている。この電解水製造装置を用いれば、残留塩素濃度とｐＨが所定の範囲即ち残留塩素濃度１．０〜２００ｐｐｍ、ｐＨ３〜７に調整された電解水を製造することができる。
また、特開平１０−３０９５８２号公報には、一定濃度の電解質溶液を一定量電解して酸性電解水を生成し、該酸性電解水に酢酸、りん酸等の無機酸の緩衝液を添加して水素イオン濃度を調整し、酸性電解水中の次亜塩素酸濃度を安定させ、経時変化を減少させることを特徴とする酸性電解水の製造方法が記載されている。次亜塩素酸濃度は、水素イオン濃度をｐＨ値３．５〜５．５の範囲、好ましくは、ｐＨ４．５付近に調整することにより、経時変化による濃度の減少を抑制することができ、場合によっては、製造した電解水をｐＨが４．５より高い条件で保存し、殺菌等に使用するときに、ｐＨ４．５付近に調整して用いることができることが記載されている。
発明が解決しようとする課題
しかし、従来の製造装置や使用方法では、
▲１▼ｐＨ３以下の低いｐＨに調整するには、耐酸性のある特殊な材質を用いなければならず、そのような材質を装置全体に用いた場合、装置のコストが非常に高くなり、さらに低いｐＨの被電解水を用いて電気分解を行った場合に、その際に発生する塩素ガスの処理の問題等があること、
▲２▼従来の装置で製造されたｐＨ３以上の電解水をさらにｐＨ調整するには、その時の温度、量、電解水のｐＨによって、酸等の調整剤の量が異なるため、別途ｐＨ値を監視する装置が必要となること、
▲３▼従来の装置では、加温した原水を用いることは、電気分解の際に塩素ガスが多く発生するため不可能であることから、所定の温度に電解水を調整することが不可能であること、
▲４▼たとえ、製造したｐＨ３以上の電解水を加温した用いたり、加温した水で希釈したりしたとしても、次亜塩素酸濃度が低下し、充分な殺菌効果が得られないこと、
▲５▼家庭用や、個人病院等の小さな施設で使用するには、装置自体が高価であり、しかも、長期使用するには、電極、電解槽等の維持費用がかかること、
等のこの種の酸性水溶液を広く一般に普及させるには様々な問題があった。
本発明は、家庭用や、個人病院等の小さな施設においても、除菌または消毒を目的に低価格でしかも簡便に使用できる酸性水溶液の使用方法及び供給方法を提供することを目的とする。
課題を解決するための手段
本発明者は、上記課題を解決すべく鋭意検討した結果、高有効塩素濃度、高いｐＨ値の品質が管理された電解水、または次亜塩素酸及び／またはその塩を希釈した水溶液を大量に一括製造し、一定量を密閉容器に保存し、その容器の容量に合わせて使用するだけの量の電解水等の活性化剤を、容器詰めした電解水等と一緒に提供し、両者を混合しさらに所定の温度の水で希釈して使用することにより、電解水等の有する殺菌効果を失わずに、しかも低価格で簡便に使用することできることを見出し、本発明を完成するに至った。
すなわち、本発明は、
（１）有効塩素濃度が２０〜１０００ｐｐｍでありかつｐＨ５〜８の水溶液を容器内に密閉保存し、使用時までの間に、前記水溶液中の塩素成分の活性化を促進する活性化剤を添加し、所定温度の水で希釈して用いることを特徴とする水溶液の使用方法に関し、
（２）前記容器内に密閉保存した水溶液一定量と、該一定量に対して必要量の前記活性化剤を容器詰めし、提供することを特徴とする（１）に記載の水溶液の使用方法、
（３）前記水溶液中の塩素成分の活性化を促進する活性化剤を添加し、水で希釈した後の水溶液中の有効塩素濃度が２〜４０ｐｐｍ、ｐＨ２．０〜０．３の範囲であることを特徴とする（１）または（２）に記載の水溶液の使用方法、
（４）前記水溶液中の塩素成分の活性化を促進する活性化剤が、クエン酸、りん酸、塩酸からなる群から選ばれる少なくとも１種を含有する水溶液であることを特徴とする（１）〜（３）のいずれかに記載の水溶液の使用方法、
（５）有効塩素濃度が２０〜１０００ｐｐｍでありかつｐＨ５〜８の水溶液が、水または電解質を含む水溶液を電気分解して得られた電解水であることを特徴とする（１）〜（４）のいずれかに記載の水溶液の使用方法、
（６）有効塩素濃度が５０〜２００ｐｐｍであり、かつｐＨ５〜８の電解水が、塩化ナトリウムを０．２〜０．８重量％添加した水溶液またはさらに重炭酸ナトリウムもしくは水酸化ナトリウムを添加した水溶液を電解槽中で電気分解して得られた電解水であることを特徴とする（１）〜（５）のいずれかに記載の水溶液の使用方法、
（７）有効塩素濃度が２０〜１０００ｐｐｍでありかつｐＨ５〜８の水溶液が、次亜塩素酸及び／またはその塩を希釈して調整された水溶液であることを特徴とする（１）〜（４）のいずれかに記載の水溶液の使用方法、
（８）（１）〜（７）のいずれかに記載された使用方法で使用されることを特徴とする水溶液に関する。
さらに、
（９）有効塩素濃度が２０〜１０００ｐｐｍでありかつｐＨ５〜８の容器内に密閉保存された一定量の水溶液と、該一定量の水溶液に使用時までの間に添加される必要量容器詰めされた前記水溶液中の塩素成分の活性化を促進する活性化剤を、提供することを特徴とする水溶液の供給方法に関し、
（１０）該一定量の水溶液に使用時までの間に添加される必要量が、前記水溶液中の塩素成分の活性化を促進する活性化剤を添加し、水で５〜１０倍に希釈した後の水溶液中の有効塩素濃度が２〜４０ｐｐｍ、ｐＨ２．０〜３．０の範囲にする量であることを特徴とする（９）に記載の水溶液の供給方法、
（１１）前記水溶液中の塩素成分の活性化を促進する活性化剤が、クエン酸、りん酸、塩酸からなる群から選ばれる少なくとも１種を含有する水溶液であることを特徴とする（９）または（１０）に記載の水溶液の供給方法、
（１２）有効塩素濃度が２０〜１０００ｐｐｍでありかつｐＨ５〜８の水溶液が、水または電解質を含む水溶液を電気分解して得られた電解水であることを特徴とする（９）〜（１１）のいずれかに記載の水溶液の供給方法、
（１３）有効塩素濃度が５０〜２００ｐｐｍであり、かつｐＨ５〜８の電解水が、塩化ナトリウムを０．２〜０．８重量％添加した水溶液またはさらに重炭酸ナトリウムもしくは水酸化ナトリウムを添加した水溶液を電解槽中で電気分解して得られた電解水であることを特徴とする（９）〜（１２）のいずれかに記載の水溶液の供給方法、
（１４）有効塩素濃度が２０〜１０００ｐｐｍでありかつｐＨ５〜８の水溶液が、次亜塩素酸及び／またはその塩を希釈して調整された水溶液であることを特徴とする（９）〜（１２）のいずれかに記載の水溶液の使用方法、
（１５）（９）〜（１４）のいずれかに記載された供給方法で使用されることを特徴とする水溶液に関する。
発明の実施の形態
本発明である電解水等の水溶液の使用方法は、有効塩素濃度が２０〜１０００ｐｐｍでありかつｐＨ５〜８の電解水を容器内に密閉保存し、使用時までの間に、前記水溶液中の塩素の活性化を促進する活性化剤を添加し、所定温度の水で希釈して用いることを特徴とする。
また、本発明である電解水等の水溶液の供給方法は、有効塩素濃度が２０〜１０００ｐｐｍでありかつｐＨ５〜８の容器内に密閉保存された一定量の水溶液と、該一定量の水溶液に使用時までの間に添加される必要量容器詰めされた前記水溶液中の塩素の活性化を促進する活性化剤を、提供することを特徴とする。
本発明に使用または供給される電解水等の水溶液は、有効塩素濃度が、２０〜１０００ｐｐｍでありかつ、ｐＨ５〜８の電解水等の水溶液であれば、その製造方法は特に限定されず、アノードとカソードの間に隔膜を有する電解槽、または隔膜を有さない電解槽を用いて少量の電解質の溶解した溶液を電気分解する方法等の公知の方法で製造することができる。
また、市販等されている次亜塩素酸及び／またはその塩またはその水溶液を、有効塩素濃度が２０〜１０００ｐｐｍの範囲になるように希釈し、ｐＨが５〜８の範囲に入るように調整することによっても得ることができる。
電解水を得る具体的な方法としては、蒸留水または水道水に塩化ナトリウムを０．２〜０．８重量％添加した水溶液、または、ｐＨが７〜８の電解水を得るために電解によって生成する酸を中和するために該水溶液にさらに必要量の重炭酸ナトリウムまたは水酸化ナトリウムを添加し、アノード側とカソード側の間に隔膜を有さない無隔膜電解槽を用いて電解する方法を例示することができる。
隔膜を有する電解槽を用いた場合、陽極側に酸性電解水、陰極側にアルカリ性電解水が生成されるので、必要に応じて両者を混合してｐＨ調整した電解水溶液を本発明に用いることもできる。
本発明に用いられる電解水等の水溶液の有効塩素濃度は、２０〜１０００ｐｐｍの範囲が好ましい。２０ｐｐｍ未満では、密閉保存したとしても有効塩素濃度の低下により使用時に充分な殺菌活性をしめさず、容器詰めして運搬する場合に容器本数が増え不便である。また、有効塩素濃度が高ければ保存する点では好ましいが、１０００ｐｐｍより高い濃度場合、運搬、保存上の安全の問題、活性化剤を添加した際に発熱により一時的に発生する塩素ガス等の酸性ガスの臭気が強くなるという問題がある。
以上のように調整した電解水等の本発明水溶液を保存する容器としては、密閉できるものであれば特に制限されないが、ｐＨが７以下の場合には、耐酸性を有する材質の容器、ｐＨが８以上の場合には耐アルカリ性を有する材質の容器を用いるのが好ましく、持ち運ぶための重量を考慮した場合に、樹脂製容器が好ましい。また、容器の容量は、１度に使用する量によって任意に選択することができ、例えば、５００ｍｌ〜１Ｌ詰め程度の容量で提供し、５〜１０倍に希釈すれば、一度に電解水として、２Ｌ〜１０Ｌ程度を調整でき、個人病院等で治療行為に使用した１日分の医療器具の殺菌に使用する場合に、ある程度充分な量であるといえる。
保存方法は、有効成分の一つである次亜塩素酸の分解を防ぐため、冷暗所に保存するのが好ましく、紫外線等を遮光するために着色した容器を用いた方が好ましい場合がある。
本発明に用いられる電解水等の水溶液中の塩素成分の活性化を促進する活性化剤は、化学的に安定な型で保存されていた塩素成分を、殺菌作用がもっとも強く現れる型に変化させる剤をいう。なお、塩素成分とは、塩素原子を含み、殺菌効果を有する化合物群をいい、具体的には、次亜塩素酸、亜塩素酸、塩素酸、または、それらの無機塩等を例示することができ、特に、次亜塩素酸、次亜塩素酸塩を好ましく例示することができる。
上記活性化剤として、具体的には、ｐＨ調節剤を例示することができ、特に、ｐＨを１〜３、好ましくは１〜２の強酸性にする調整する剤を例示することができる。具体的には、有機酸、無機酸等例示することができ、中でも、クエン酸、りん酸、塩酸等を好ましく例示することができる。
調整剤を添加した後のｐＨが１より低い場合には、塩素成分の分解が速く、ｐＨが３より大きい場合には、希釈して使用するする際ｐＨの上昇が見られ充分な殺菌効果が得られないというおそれがある。
提供する電解水等の本発明水溶液は、一定の品質管理のもと工業的にある程度大量に製造され密閉保存されるため、容器単位で、活性化剤の必要量をあらかじめ把握することができるので、一定量の電解水に対して、必要量の活性化剤を容器づめして提供することにより、使用する側は、ｐＨ計等を用いてｐＨを管理する必要がなく、使用時に両者を混合して希釈するだけで、殺菌効果の高いしかも安全な電解水等の本発明水溶液を簡便に入手することができるので好ましい。
上記活性化剤を密閉保存された高有効塩素濃度を有する電解水等の水溶液に添加する時期は、実際に使用する前であれば特に制限されないが、塩素成分は徐々に分解するため、使用直前に添加するのが好ましい。活性化剤を添加後、特に攪拌等を行うことなく、上水で希釈して使用することができる。
本発明の電解水等の水溶液は、活性剤添加後、所定温度の水で希釈して用いることを特徴とする。とくに、従来の電解水製造装置では、実現か困難であった電解水等の水溶液の温度調整を、本発明の使用方法では、希釈に用いる水の温度を適度に調整することによって容易に行うことができる。
本発明の水で希釈した後の使用時の電解水等の水溶液中の有効塩素濃度は、２〜４０ｐｐｍ、ｐＨが２．０〜３．０の範囲であるのが好ましい。有効塩素濃度が２ｐｐｍ未満では、充分な殺菌効果が得られず、４０ｐｐｍを超える濃度では、生体への刺激性が発現される。また、ｐＨ２未満では、塩素成分の分解が速く、ｐＨ３を超えると、前記有効塩素濃度では、充分な殺菌効果が得られない。すなわち、ｐＨを２〜３の比較的低い範囲で使用することにより、２〜４０ｐｐｍという低い有効塩素濃度でも充分な殺菌効果が得られ、それ故に、任意の温度に設定した水で希釈することによって多少塩素成分が分解、揮散したとしても充分な殺菌効果が得られるため、本発明のような使用方法が可能になったといえる。電解水を所定温度に調整できることにより、特に、外気温の低い冬の季節において電解水等の本発明水溶液を皮膚等の殺菌に用いる場合には、低い水温による刺激が少なく効果的に使用することができるといえる。
また、低い有効塩素濃度で使用できるため、人体への影響がまったくなく、電解水で殺菌後、水洗い等の別の処理をすることなく、殺菌されたものを使用することができ、食品であれば、そのまま食用に供することもできる。
また、本発明の使用方法または供給方法は、有効塩素濃度が２０〜１０００ｐｐｍでありかつｐＨ５〜８の電解水等の水溶液を容器内に密閉保存し、使用時までの間にさらに、あらかじめ次亜塩素酸で処理した香料を添加することもできる。本発明の電解水等の水溶液は、器具等の殺菌のみならず、皮膚、粘膜または創傷面の殺菌、口腔内の殺菌等の医療行為に使用されている。その場合、塩素系臭気の問題が生じる場合がある。
このような問題を解決する手段として、香料を用いることはよく行われるが、通常使用される香料を前記電解水等の本発明水溶液に添加して使用すると多くの場合に、有効塩素成分が香料と反応し、殺菌効果を著しく低下させるという問題があった。この問題に対して、電気分解法等で生成された有効塩素成分である次亜塩素酸またはその塩であらかじめ処理された香料を用いることで解決することができた。
用いる香料は、次亜塩素酸またはその塩で処理した場合に香気成分が変質するものは好ましくないが、多くのものはこの種の変質が見られない。具体的には、ロース、ラベンダー、ペパーミント等の香料を用いることができる。香料の処理方法は、例えばアルコール等の水溶性溶媒の香料溶液に、次亜塩素酸またはその塩及び酸を添加する方法、または香料の含まれる電解質含有水溶液を用いて電気分解する方法等例示することがきる。
以上のように調整された香料を前記した高濃度の電解水等の本発明水溶液、活性化剤添加後の電解水等の本発明水溶液、または希釈後の電解水等の本発明水溶液に添加して使用することにより、臭気の問題を解決することができ、治療に用いる場合には、香気成分による治療効果をプラスすることもできる。
本発明の電解水等の水溶液、または添加用香料には、必要に応じて他の成分を添加することもできる。例えば、口腔内洗浄用として、薬用成分であるグルコン酸クロルヘキシン、フッ化ナトリウム等、甘味成分としてキシリトール、保湿剤としてのグリセリン等を添加することができる。
以下、本発明を実施例を用いて更に詳細に説明するが、本発明は実施例に限定されるものではない。
実施例１
水道水４０００ｍｌも１６ｇの塩化ナトリウムを加え、単層平板型電解槽にて３０分間通電して電気分解を行ったところ、ｐＨ７．２、酸化還元電位５６０ｍＶ、活性塩素濃度２２０ｐｐｍの電解水を得た。これら電解水を１０００ｍｌ容量の角型プラスチック容器に４本に分注し密栓した。そのうち、２本を室温で暗所に保存し、表１に示す各経過日数において１部を採取し、希塩酸を用いてｐＨを調整し水で１０倍に希釈した後、有効塩素濃度、酸化還元電位を測定した。その結果を表１にまとめて示す。
比較例１
実施例１で１Ｌプラスチック容器に分注した電解水に希塩酸を加えｐＨ２．２に調整後、密栓し、室温で暗所に保存した。表１に示す経過日数において１部採取し１０倍に希釈した後、有効塩素濃度、酸化還元電位を測定した。その結果を表１にまとめて示す。
実施例２
実施例１と同様にして製造、分注して２８日間保存した後、希塩酸（濃塩酸４ｍｌを適当に希釈したもの）を加え、さらに１０倍に希釈して電解水を調整した。その時のｐＨは２．６であり、有効塩素濃度は、１５ｐｐｍであった。表２に示す各菌液０．１ｍｌを０．９ｍｌの調整した前記電解水で３分間処理した後、ｎｕｔｒｉｅｎｔ ｂｒｏｔｈで１０倍段階希釈して生菌数を求めた。尚、比較のために電解水未処理区を設けた。
実施例２において、密閉保存した電解水を希釈する水の温度を６０℃にして行った以外同様の電解水を調整した。調整した電解水のｐＨは、２．７であり、有効塩素濃度は１３ｐｐｍであり、同様の殺菌効果を有していた。
発明の効果
以上、述べたように、本発明の使用方法を用いることで、安価に、簡便にしかも安全に強酸性電解水を使用することができ、しかも、温度調節を容易に行うことができる。強酸性電解水は、人体に対しても無害であるにも係わらず、強い殺菌効果を有しことから、医療、食品加工等の現場で使用することができ、本発明の方法を用いることで、更に産業上の利用価値が向上するといえる。 Technical field The present invention relates to medical, food industry, food and beverage industry, veterinary medicine, such as sterilization of various instruments and workers' hands in laboratories that handle living organisms, disinfection in hospitals, disinfection in plant cultivation, etc. The present invention relates to a novel method for supplying an acidic aqueous solution having a disinfecting effect such as bactericidal and antibacterial properties used in a livestock industry, a public place requiring sanitation, a place requiring sterilization and the like, or a method for using the same.
Prior art Electrolyzed water is known as an acidic aqueous solution used for the purpose of sterilization or disinfection. Conventionally, such electrolyzed water is, as a minimum, a DC power supply for electrolysis, an anode, a cathode, and both electrodes. And an electrolytic cell separated into an anode chamber and a cathode chamber, a raw water supplied from a raw water introduction pipe, and a sodium chloride aqueous solution supplied from a sodium chloride aqueous solution adding means. An introduction pipe for supplying electrolyzed water to the anode chamber and the cathode chamber, a discharge pipe for taking out generated water from each of the anode chamber and the cathode chamber, a generated water taken out from the anode chamber, and a branch from the raw water introduction pipe In addition, the electrolyzed water producing apparatus has a means for mixing and diluting the raw water supplied from the diluting raw water introduction pipe and / or the produced water taken out from the cathode chamber.
Japanese Patent Application Laid-Open No. 4-94785 discloses addition of raw water, a sodium chloride aqueous solution supplied from a sodium chloride aqueous solution adding means, and a hydrochloric acid aqueous solution to one of the electrolytic cells having no diaphragm between the cathode and the anode. Connected supply pipe for electrolyzed water mixed with hydrochloric acid aqueous solution supplied from the means, and provided with a lead-out pipe for taking out the electrolyzed water in the other of the electrolyzer, so that the electrolyzed water and raw water can be mixed Thus, an electrolyzed water production apparatus is described in which the raw water introduction pipe and the electrolyzed water outlet pipe are connected. If this electrolyzed water production apparatus is used, it is possible to produce electrolyzed water whose residual chlorine concentration and pH are adjusted to a predetermined range, that is, a residual chlorine concentration of 1.0 to 200 ppm and a pH of 3 to 7.
Japanese Patent Application Laid-Open No. 10-309582 discloses that an electrolytic solution of a certain concentration is electrolyzed to produce an acidic electrolyzed water, and a buffer solution of an inorganic acid such as acetic acid or phosphoric acid is added to the acidic electrolyzed water. There is described a method for producing acidic electrolyzed water characterized by adjusting the hydrogen ion concentration, stabilizing the hypochlorous acid concentration in the acidic electrolyzed water, and reducing the change with time. Hypochlorous acid concentration can suppress decrease in concentration due to change over time by adjusting the hydrogen ion concentration to a pH value in the range of 3.5 to 5.5, preferably around pH 4.5. In some cases, the produced electrolyzed water is stored under conditions where the pH is higher than 4.5, and can be adjusted to around pH 4.5 when used for sterilization or the like.
Problems to be solved by the invention However, in the conventional manufacturing apparatus and method of use,
(1) In order to adjust to a low pH of pH 3 or lower, a special material having acid resistance must be used. If such a material is used for the entire apparatus, the cost of the apparatus becomes very high. When electrolysis is performed using low pH electrolyzed water, there is a problem of the treatment of chlorine gas generated at that time,
(2) In order to further adjust the pH of electrolyzed water having a pH of 3 or higher produced by a conventional apparatus, the amount of the adjusting agent such as acid differs depending on the temperature, amount, and pH of the electrolyzed water. The need for monitoring equipment,
(3) In the conventional apparatus, it is impossible to adjust the electrolyzed water to a predetermined temperature because it is impossible to use heated raw water because a large amount of chlorine gas is generated during electrolysis. There is,
(4) Even if the produced electrolyzed water having a pH of 3 or higher is used warmed or diluted with warmed water, the hypochlorous acid concentration is lowered and a sufficient sterilizing effect cannot be obtained.
(5) The device itself is expensive for use in homes and small facilities such as private hospitals, and for long-term use, it requires maintenance costs for electrodes, electrolyzers, etc.
There have been various problems in widely disseminating this kind of acidic aqueous solution.
An object of the present invention is to provide a method for using and supplying an acidic aqueous solution that can be used at low cost and simply for the purpose of sterilization or disinfection even in small facilities such as households and private hospitals.
Means for Solving the Problems As a result of diligent studies to solve the above problems, the present inventors have found that electrolyzed water in which the quality of high effective chlorine concentration and high pH value is controlled, or hypochlorous acid and / Or manufacture a large amount of an aqueous solution diluted with its salt, store a certain amount in a sealed container, and electrolyze the amount of activator such as electrolyzed water enough to use according to the capacity of the container Providing together with water, etc., mixing both and further diluting with water of a predetermined temperature, it can be used easily at a low price without losing the bactericidal effect of electrolytic water, etc. The headline and the present invention were completed.
That is, the present invention
(1) An aqueous solution having an effective chlorine concentration of 20 to 1000 ppm and a pH of 5 to 8 is hermetically stored in a container, and an activator that promotes activation of the chlorine component in the aqueous solution is added until use. And using an aqueous solution characterized by being diluted with water at a predetermined temperature,
(2) A method of using the aqueous solution according to (1), wherein a certain amount of the aqueous solution sealed and stored in the container and a necessary amount of the activator are packed in the container and provided. ,
(3) The effective chlorine concentration in the aqueous solution after adding an activator for promoting the activation of the chlorine component in the aqueous solution and diluting with water is in the range of 2 to 40 ppm, pH 2.0 to 0.3. A method of using the aqueous solution according to (1) or (2),
(4) The activator for promoting the activation of the chlorine component in the aqueous solution is an aqueous solution containing at least one selected from the group consisting of citric acid, phosphoric acid and hydrochloric acid (1) Use method of aqueous solution in any one of-(3),
(5) The aqueous solution having an effective chlorine concentration of 20 to 1000 ppm and a pH of 5 to 8 is electrolyzed water obtained by electrolyzing water or an aqueous solution containing an electrolyte (1) to (4) A method of using the aqueous solution according to any one of
(6) An aqueous solution having an effective chlorine concentration of 50 to 200 ppm and an electrolyzed water having a pH of 5 to 8 added with 0.2 to 0.8% by weight of sodium chloride, or an aqueous solution further added with sodium bicarbonate or sodium hydroxide. The method for using the aqueous solution according to any one of (1) to (5), wherein the aqueous solution is electrolyzed water obtained by electrolysis in an electrolytic cell,
(7) The aqueous solution having an effective chlorine concentration of 20 to 1000 ppm and a pH of 5 to 8 is an aqueous solution prepared by diluting hypochlorous acid and / or a salt thereof (1) to (4) ) A method of using the aqueous solution according to any one of
(8) It is related with the aqueous solution characterized by being used by the usage method described in any one of (1)-(7).
further,
(9) A certain amount of aqueous solution sealed in a container having an effective chlorine concentration of 20 to 1000 ppm and pH 5 to 8 and a necessary amount to be added to the certain amount of aqueous solution until use In addition, the present invention relates to a method for supplying an aqueous solution, characterized by providing an activator that promotes activation of a chlorine component in the aqueous solution.
(10) Necessary amount to be added to the fixed amount of aqueous solution before use is the addition of an activator for promoting the activation of the chlorine component in the aqueous solution, and diluted 5 to 10 times with water The method for supplying an aqueous solution according to (9), wherein the effective chlorine concentration in the subsequent aqueous solution is an amount that makes the pH range from 2 to 40 ppm and a pH of 2.0 to 3.0,
(11) The activator for promoting the activation of the chlorine component in the aqueous solution is an aqueous solution containing at least one selected from the group consisting of citric acid, phosphoric acid and hydrochloric acid (9) Or the method for supplying an aqueous solution according to (10),
(12) The aqueous solution having an effective chlorine concentration of 20 to 1000 ppm and a pH of 5 to 8 is electrolyzed water obtained by electrolyzing water or an aqueous solution containing an electrolyte (9) to (11) A method for supplying the aqueous solution according to any one of
(13) An aqueous solution having an effective chlorine concentration of 50 to 200 ppm and an electrolyzed water of pH 5 to 8 added with 0.2 to 0.8% by weight of sodium chloride, or an aqueous solution further added with sodium bicarbonate or sodium hydroxide The method for supplying an aqueous solution according to any one of (9) to (12), wherein the aqueous solution is electrolyzed water obtained by electrolysis in an electrolytic cell,
(14) The aqueous solution having an effective chlorine concentration of 20 to 1000 ppm and a pH of 5 to 8 is an aqueous solution prepared by diluting hypochlorous acid and / or a salt thereof (9) to (12 ) A method of using the aqueous solution according to any one of
(15) The present invention relates to an aqueous solution characterized by being used in the supply method described in any one of (9) to (14).
Using an aqueous solution of electrolyte such as water forms <br/> a present invention embodiment of the invention, the effective chlorine concentration was sealed save a is and the electrolytic water pH5~8 into the container 20～1000Ppm, until use In the meantime, an activator for accelerating the activation of chlorine in the aqueous solution is added and diluted with water at a predetermined temperature.
In addition, the method for supplying an aqueous solution such as electrolyzed water according to the present invention is used for a certain amount of aqueous solution sealed in a container having an effective chlorine concentration of 20 to 1000 ppm and pH 5 to 8, and the certain amount of aqueous solution. It is characterized by providing an activator that promotes the activation of chlorine in the aqueous solution in a required amount container that is added by the time.
The aqueous solution such as electrolyzed water used or supplied in the present invention is not particularly limited as long as the effective chlorine concentration is 20 to 1000 ppm and the aqueous solution such as electrolyzed water having a pH of 5 to 8 is used. It can be produced by a known method such as an electrolysis method in which an electrolytic cell having a diaphragm between the cathode and the cathode or an electrolytic cell having no diaphragm is used to electrolyze a solution in which a small amount of electrolyte is dissolved.
Further, commercially available hypochlorous acid and / or a salt thereof or an aqueous solution thereof is diluted so that the effective chlorine concentration is in the range of 20 to 1000 ppm and adjusted so that the pH is in the range of 5 to 8. Can also be obtained.
As a specific method for obtaining electrolyzed water, an aqueous solution obtained by adding 0.2 to 0.8% by weight of sodium chloride to distilled water or tap water, or generated by electrolysis to obtain electrolyzed water having a pH of 7 to 8 A method of adding a necessary amount of sodium bicarbonate or sodium hydroxide to the aqueous solution to neutralize the acid to be electrolyzed, and electrolyzing using a non-diaphragm electrolyzer having no diaphragm between the anode side and the cathode side. It can be illustrated.
When an electrolytic cell having a diaphragm is used, acidic electrolyzed water is generated on the anode side and alkaline electrolyzed water is generated on the cathode side. Therefore, if necessary, an electrolytic aqueous solution in which both are mixed and pH adjusted may be used in the present invention. it can.
The effective chlorine concentration of the aqueous solution such as electrolyzed water used in the present invention is preferably in the range of 20 to 1000 ppm. If it is less than 20 ppm, even if it is stored in a sealed state, the effective chlorine concentration is lowered, so that it does not show sufficient bactericidal activity at the time of use, and the number of containers is increased and inconvenient when packed and transported. In addition, if the effective chlorine concentration is high, it is preferable in terms of storage, but if the concentration is higher than 1000 ppm, the safety of transportation and storage, acidity such as chlorine gas that is temporarily generated due to heat generation when an activator is added, etc. There is a problem that the odor of gas becomes strong.
The container for storing the aqueous solution of the present invention such as electrolyzed water adjusted as described above is not particularly limited as long as it can be sealed, but when the pH is 7 or less, the container is made of a material having acid resistance, and the pH is In the case of 8 or more, it is preferable to use a container made of a material having alkali resistance, and a resin container is preferable in consideration of the weight for carrying. In addition, the capacity of the container can be arbitrarily selected according to the amount used at a time, for example, provided in a capacity of about 500 ml to 1 L, and diluted 5 to 10 times as electrolyzed water at once, About 2L-10L can be adjusted, and it can be said that it is a sufficient amount to some extent when it is used for sterilization of medical equipment for one day used for therapeutic action in a private hospital or the like.
In order to prevent the decomposition of hypochlorous acid, which is one of the active ingredients, the storage method is preferably stored in a cool and dark place, and in some cases, it is preferable to use a colored container for shielding ultraviolet rays or the like.
The activator for accelerating the activation of the chlorine component in the aqueous solution such as electrolyzed water used in the present invention changes the chlorine component stored in a chemically stable form into a form in which the bactericidal action is most strongly exhibited. An agent. The chlorine component refers to a group of compounds containing a chlorine atom and having a bactericidal effect. Specifically, hypochlorous acid, chlorous acid, chloric acid, or inorganic salts thereof may be exemplified. In particular, hypochlorous acid and hypochlorite can be preferably exemplified.
Specific examples of the activator include a pH adjuster, and in particular, an agent for adjusting the pH to a strong acidity of 1 to 3, preferably 1 to 2. Specifically, organic acids and inorganic acids can be exemplified, and among them, citric acid, phosphoric acid, hydrochloric acid and the like can be preferably exemplified.
When the pH after adding the regulator is lower than 1, the decomposition of the chlorine component is fast, and when the pH is higher than 3, the pH is increased when used diluted, and a sufficient bactericidal effect is obtained. There is a risk that it cannot be obtained.
Since the aqueous solution of the present invention such as electrolyzed water to be provided is manufactured and stored in a large amount industrially under a certain quality control, the necessary amount of the activator can be grasped in advance for each container. By providing the required amount of activator in a container for a certain amount of electrolyzed water, the user does not need to control the pH using a pH meter, etc. The aqueous solution of the present invention, such as electrolyzed water having a high bactericidal effect and safe, can be easily obtained simply by diluting.
The timing of adding the activator to an aqueous solution such as electrolyzed water having a high effective chlorine concentration stored in a hermetically sealed state is not particularly limited as long as it is before actual use, but the chlorine component is gradually decomposed. It is preferable to add to. After adding an activator, it can be used by diluting with clean water without particularly stirring.
The aqueous solution such as electrolyzed water of the present invention is characterized by being diluted with water at a predetermined temperature after addition of an activator. In particular, it is easy to adjust the temperature of an aqueous solution such as electrolyzed water, which has been difficult to achieve with conventional electrolyzed water production apparatuses, by appropriately adjusting the temperature of water used for dilution in the method of use of the present invention. Can do.
The effective chlorine concentration in the aqueous solution such as electrolyzed water at the time of use after being diluted with the water of the present invention is preferably 2 to 40 ppm and the pH is in the range of 2.0 to 3.0. If the effective chlorine concentration is less than 2 ppm, a sufficient bactericidal effect cannot be obtained, and if it exceeds 40 ppm, irritation to the living body is expressed. When the pH is less than 2, the chlorine component is rapidly decomposed. When the pH exceeds 3, the sufficient sterilizing effect cannot be obtained at the effective chlorine concentration. That is, by using the pH in a relatively low range of 2 to 3, a sufficient bactericidal effect can be obtained even at an effective chlorine concentration as low as 2 to 40 ppm. Therefore, by diluting with water set at an arbitrary temperature. Even if the chlorine component is decomposed or volatilized to some extent, a sufficient bactericidal effect can be obtained, and it can be said that the method of use as in the present invention is now possible. The ability to adjust the electrolyzed water to a predetermined temperature, especially when the aqueous solution of the present invention such as electrolyzed water is used for sterilization of the skin etc. in the winter season when the outside air temperature is low, should be used effectively with little irritation due to the low water temperature. Can be said.
In addition, since it can be used at a low effective chlorine concentration, it has no effect on the human body, and after being sterilized with electrolyzed water, it can be sterilized without further treatment such as washing with water. For example, it can be used for food.
In addition, according to the method of use or supply of the present invention, an aqueous solution such as electrolyzed water having an effective chlorine concentration of 20 to 1000 ppm and a pH of 5 to 8 is sealed and stored in a container. A fragrance treated with chloric acid can also be added. The aqueous solution such as electrolyzed water of the present invention is used not only for sterilization of instruments and the like, but also for medical activities such as sterilization of skin, mucous membrane or wound surface, and sterilization of oral cavity. In that case, a problem of chlorine-based odor may occur.
As a means for solving such problems, a fragrance is often used. However, when a commonly used fragrance is added to the aqueous solution of the present invention such as the electrolyzed water, the effective chlorine component is often used as a fragrance. There is a problem that the bactericidal effect is remarkably lowered. This problem could be solved by using a perfume pretreated with hypochlorous acid or a salt thereof, which is an effective chlorine component produced by electrolysis.
As the fragrance to be used, those which change the flavor component when treated with hypochlorous acid or a salt thereof are not preferable, but many of them do not show this kind of alteration. Specifically, fragrances such as loin, lavender and peppermint can be used. Examples of the method for treating a fragrance include a method of adding hypochlorous acid or a salt thereof and an acid to a fragrance solution of a water-soluble solvent such as alcohol, or a method of performing electrolysis using an electrolyte-containing aqueous solution containing the fragrance. I can do it.
The perfume prepared as described above is added to the aqueous solution of the present invention such as high-concentration electrolytic water as described above, the aqueous solution of the present invention such as electrolytic water after addition of an activator, or the present aqueous solution such as electrolytic water after dilution. By using it, the problem of odor can be solved, and when used for treatment, the therapeutic effect of the fragrance component can be added.
Other components may be added to the aqueous solution of the present invention, such as electrolyzed water, or the perfume for addition, if necessary. For example, chlorhexine gluconate and sodium fluoride that are medicinal components, xylitol as a sweetening component, glycerin and the like as a moisturizing agent, and the like can be added for oral cleaning.
EXAMPLES Hereinafter, although this invention is demonstrated still in detail using an Example, this invention is not limited to an Example.
Example 1
When 4000 ml of tap water was added with 16 g of sodium chloride and electrolysis was carried out for 30 minutes in a single-layer flat plate electrolytic cell, electrolyzed water having a pH of 7.2, an oxidation-reduction potential of 560 mV, and an active chlorine concentration of 220 ppm was obtained. . The electrolyzed water was dispensed into four 1000 ml capacity square plastic containers and sealed. Two of them were stored at room temperature in a dark place, 1 part was collected at each elapsed time shown in Table 1, pH was adjusted with dilute hydrochloric acid and diluted 10 times with water, then effective chlorine concentration, redox The potential was measured. The results are summarized in Table 1.
Comparative Example 1
Diluted hydrochloric acid was added to the electrolyzed water dispensed in a 1 L plastic container in Example 1 to adjust the pH to 2.2, and then sealed and stored at room temperature in a dark place. After collecting 1 part and diluting 10 times in the elapsed days shown in Table 1, the effective chlorine concentration and the oxidation-reduction potential were measured. The results are summarized in Table 1.
Example 2
The product was prepared and dispensed in the same manner as in Example 1 and stored for 28 days. Diluted hydrochloric acid (a solution obtained by appropriately diluting 4 ml of concentrated hydrochloric acid) was added, and the mixture was further diluted 10 times to prepare electrolyzed water. The pH at that time was 2.6, and the effective chlorine concentration was 15 ppm. Each bacterial solution 0.1 ml shown in Table 2 was treated with 0.9 ml of the adjusted electrolyzed water for 3 minutes, and then diluted 10-fold with a nutrient broth to determine the viable cell count. For comparison, an electrolyzed water untreated section was provided.
In Example 2, the same electrolyzed water was prepared except that the temperature of the water for diluting the electrolyzed water stored hermetically was changed to 60 ° C. The pH of the adjusted electrolyzed water was 2.7, the effective chlorine concentration was 13 ppm, and the same bactericidal effect was obtained.
Effect of the invention As described above, by using the method of use of the present invention, it is possible to use strongly acidic electrolyzed water at a low cost, simply and safely, and easily adjust the temperature. It can be carried out. Although strongly acidic electrolyzed water is harmless to the human body, it has a strong bactericidal effect, so it can be used in the field of medicine, food processing, etc. Furthermore, it can be said that the industrial utility value is further improved.
Claims (7)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001399351 | 2001-12-28 | ||
| JP2001399351 | 2001-12-28 | ||
| PCT/JP2002/013872 WO2003057261A1 (en) | 2001-12-28 | 2002-12-27 | Method of supplying aqueous solution for sterilization and disinfection and method of using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2003057261A1 JPWO2003057261A1 (en) | 2005-05-12 |
| JP3648569B2 true JP3648569B2 (en) | 2005-05-18 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003557618A Expired - Fee Related JP3648569B2 (en) | 2001-12-28 | 2002-12-27 | Method for supplying and using aqueous solution for disinfection or disinfection purposes |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP3648569B2 (en) |
| AU (1) | AU2002367269A1 (en) |
| WO (1) | WO2003057261A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015029263A1 (en) * | 2013-08-30 | 2015-03-05 | 株式会社エピオス | Cleaning solution and manufacturing method therefor |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH078768B2 (en) * | 1988-06-06 | 1995-02-01 | ジプコム株式会社 | Sterilized water |
| JP2619756B2 (en) * | 1991-11-07 | 1997-06-11 | 株式会社オムコ | Sterilized water production method |
| JPH08164189A (en) * | 1994-12-15 | 1996-06-25 | Morinaga Milk Ind Co Ltd | Sterilization method |
| JP3553242B2 (en) * | 1995-11-02 | 2004-08-11 | 日機装株式会社 | Hemodialysis equipment Weakly acidic electrolyzed acidic water generator for sterilization |
| JP3728018B2 (en) * | 1996-05-10 | 2005-12-21 | ホシザキ電機株式会社 | Weakly acidic chlorinated water, method and apparatus for producing the same |
| JP2000070346A (en) * | 1998-09-01 | 2000-03-07 | Kinosui Kenkyusho:Kk | Electrolyzed water storage device |
| JP3475875B2 (en) * | 1998-10-15 | 2003-12-10 | ダイキン工業株式会社 | Electrolytic sterilizing water and its manufacturing apparatus |
| JP2001029955A (en) * | 1999-07-16 | 2001-02-06 | Terumo Corp | Electrolyzed water and electrolyzed water |
-
2002
- 2002-12-27 AU AU2002367269A patent/AU2002367269A1/en not_active Abandoned
- 2002-12-27 JP JP2003557618A patent/JP3648569B2/en not_active Expired - Fee Related
- 2002-12-27 WO PCT/JP2002/013872 patent/WO2003057261A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003057261A1 (en) | 2003-07-17 |
| AU2002367269A1 (en) | 2003-07-24 |
| JPWO2003057261A1 (en) | 2005-05-12 |
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