JP3467028B2 - Mineral-containing food composition - Google Patents

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a mineral-containing food composition comprising a mineral yeast.

[0002]

2. Description of the Related Art Minerals are essential for maintaining good health, and it is considered important to ingest various minerals in good balance. Currently, several kinds of health foods with high mineral content are marketed. However, it is difficult to take various kinds of minerals in a well-balanced manner because such foods with high mineral content contain few kinds of minerals and have poor mineral balance. The situation. Also, there are few foods high in minerals containing trace elements such as copper, manganese, and molybdenum, and there is no product containing mineral yeast that has good absorption even if it contains these three kinds.

JP-A-11-269073 is known as a prior art for a preparation containing copper, but since the copper material used is copper chlorophyllin, a preparation design considering the absorbability of copper. Does not reach. Similarly, in the technique described in JP-A-8-208490, the calcium / magnesium ratio is not a composition suitable for absorbing calcium. Further, the technique described in Japanese Patent Laid-Open No. 5-117157 is poor in versatility because it is essential to add a polyol phosphate ester which is not allowed as a food additive. As described above, a mineral-containing food composition that can be used in a wide range of applications and has excellent absorbability has not been known.

Regarding the nutritional requirements of the 6th revised Japanese announced in 2000, 12 kinds of minerals (calcium,
Magnesium, iron, zinc, selenium, chromium, manganese,
Nutritional requirements are specified for copper, molybdenum, iodine, potassium, phosphorus). Although these minerals are indispensable for human life activity, they are currently in short supply due to the disorder of dietary habits unique to modern society. In addition, it is important to ingest minerals in a well-balanced manner, and for that purpose it is important to ingest various minerals based on their nutritional requirements.

[0005] Therefore, it is desired to provide a food composition in which minerals can be taken in a well-balanced manner.

[0006]

DISCLOSURE OF THE INVENTION The present invention is excellent in absorbability, allows a well-balanced intake of minerals, improves anemia, and reduces fatigue.
It is an object of the present invention to provide a food composition capable of recovering labor .

[0007]

[Means for Solving the Problems]

[0008] The present invention is, 1. A food composition having an anemia improving effect and a fatigue recovering effect
There are manganese, copper, molybdenum, zinc, selenium, black
As a source of ROM, at least manganese yeast, copper yeast,
Molybdenum yeast, zinc yeast, selenium yeast, chrome yeast
Mineral yeast consisting of 0.1 to 25 mass%, dolomite
40 mass% or more, heme iron 10 mass% or more, brown algae
One or more dry seaweeds selected from
1. A food composition containing 1 to 10 mass% ; Manganese yeast, copper yeast, molybdenum yeast, zinc fermentation
1-2 mass% of mother, selenium yeast, and chrome yeast
(Based on Table 1, the% of each yeast is a specific value, so the root
The food according to claim 1, wherein the food is contained.
A composition, 3. The forms of food are tablets, confectionery, granules, hard capsules.
Claim 1 or 2 in the form of a capsule or soft capsule.
The food composition described above .

The food composition of the present invention is useful for ingesting a standard amount of each mineral for maintaining and promoting health and preventing lifestyle-related diseases.

[0010]

BEST MODE FOR CARRYING OUT THE INVENTION The present invention is described in detail below.

At least the mineral yeast used in the present invention
, Manganese yeast, copper yeast, molybdenum yeast, zinc fermentation
Mother, selenium yeast, and chrome yeast. As real roots <br/> Lal yeasts containing these minerals (manganese, copper, molybdenum, iron, magnesium, zinc, selenium, chromium, iodine) by culturing the yeast in a medium supplemented with a high concentration, Yeast with absorbed minerals in the cells can be used.
These are obtained by culturing yeast in a medium to which minerals have been added, collecting the bacteria, and then performing steps such as concentration, sterilization, and drying.
Moreover, what is marketed can be used. As yeast, baker's yeast and brewer's yeast are commonly used.
Specifically, manganese yeast, copper yeast, molybdenum yeast,
Iron yeast, magnesium yeast, zinc yeast, selenium yeast, chrome yeast, iodine yeast and the like can be mentioned. In particular,
One or two of manganese yeast, copper yeast and molybdenum yeast
Combinations of more than one species can be used.

[0012] Such mineral yeast can be ingested without feeling metallic taste because the mineral is incorporated into the yeast cells. Further, the mineral yeast has a structure in which the mineral is bound to the protein to become an organism by incorporating the mineral into the yeast cells, and when applied to human, the absorption in the human body is better than that of the inorganic mineral.

These mineral yeasts are contained in the food composition,
It can be added in an amount of 0.1 to 25% by mass.

Calcium, magnesium, iron, and iodine
As a material with a high content of minerals selected from elementary materials,
Contains dolomite, heme iron and seaweed, in addition to shell powder,
Minera like iron yeast, magnesium yeast, iodine yeast
Yeast or the like can be used. Further, for the purpose of adjusting the calcium content, for example, egg shell calcium, coral calcium, sea urchin shell calcium, petrified seaweed calcium, pearl calcium, beef bone calcium, fish bone meal calcium, fish scale calcium, all that can be used in foods such as milk calcium Natural calcium can be added.

Calcium is 5 to 35 mass%, magnesium is 2 to 22 mass%, iron is 0.1 to 0.7 mass%, zinc is 0.1 to 0.7 mass%, and selenium is 0.0006 to 0. ．
02 mass%, chromium is 0.0004 to 0.02 mass%,
It is preferable to add 0.001 to 0.01% by mass of iodine to the food composition.

The mixing ratio of calcium and magnesium is 2:
When it is 1, a food composition suitable for absorbing calcium can be obtained.

Dolomite is generally obtained by roughly crushing rough dolomite, heat-sterilizing it, and then crushing it. A commercially available product can be used. Dolomite can be added in an amount of 25 to 70% by mass in the food composition. Especially 4
It is preferable to add 0 mass% or more. Natural calcium, which is added for the purpose of controlling the calcium content, such as coral calcium, is generally obtained by washing coral fossils, removing foreign substances, heat sterilization, drying and crushing. A commercially available product can be used. The shell powder is generally obtained by roughly crushing shells such as scallops and oysters, sieving, heat sterilizing, and then crushing. A commercially available product can be used. The shell powder can be blended in the food composition in an amount of 2 to 25% by mass.

Heme iron accounts for about 40% of iron contained in meat, fish, and internal organs, and has better intestinal absorption than non-heme iron. Heme iron, after enzymatic treatment of hemoglobin,
It is generally obtained by performing ultrafiltration or isochoric point precipitation and drying, but a commercially available product can be used. Heme iron can be mixed in the food composition in an amount of 9 to 25% by mass. In particular, it is preferable to add 10% by mass or more. As the seaweed, brown algae, red algae and the like or a mixture thereof can be used, and these can be blended as a dried product or a pulverized product thereof. The dried product and its pulverized product are commercially available. Seaweed is 1 to 1 in a food composition as a dried product.
10 mass% can be blended. Iron yeast, zinc yeast,
Mineral yeasts such as selenium yeast, chrome yeast, and iodine yeast can be added in the food composition in an amount of 0.1 to 25% by mass.

The food composition of the present invention may further contain an inert ingredient such as a binder, an excipient, a disintegrant and a lubricant, in addition to mineral yeast and other mineral-rich materials.

As the inactive ingredient used in the present invention, lactose, crystalline cellulose, dextrin, starch, maltose, reduced lactose, reduced maltose, sorbitol, mannitol, erythritol, xylitol, guar gum, xanthan gum, sodium alginate, corn starch,
Examples include hydrogenated vegetable oil, gum arabic, soybean dietary fiber, methyl cellulose, agar, gelatin, sucrose, glucose, sucrose fatty acid ester, magnesium stearate, vegetable oil and fat powder and the like.

As a method of using the binder, there is a method of adding water or an aqueous solution of ethanol as a binder to a mixture of the mineral yeast, the other mineral-rich material and the inactive component. The ethanol concentration of the aqueous ethanol solution to be used can be adjusted by the hygroscopicity, the average particle size, the bulk specific gravity, etc. of the mixture of the mineral yeast, the other mineral-rich material and the inactive component. If necessary, use a highly viscous solution containing guar gum, xanthan gum, starch, dextrin, soybean dietary fiber, gelatin, gum arabic, carmellose, sodium alginate, methylcellulose, agar, etc. as a binder to granulate. The working time of the process can be made more efficient.

The food composition of the present invention can be in solid form, for example tablets, tablet confections, granules, hard capsules and soft capsules. These are manufactured according to a general manufacturing method.

For example, in the case of tablets and tablet confectionery, mineral yeast and other mineral-rich materials are used as they are, or those in which excipients, binders, disintegrants or other suitable additives are evenly mixed, After granulating by an appropriate method, an appropriate additive such as a lubricant is added and compression molding is performed. Alternatively, a suitable additive such as a lubricant may be added to the mineral yeast and other high mineral content materials, and the mixture may be used as it is, or an excipient, a binder, a disintegrant or other suitable additive may be uniformly mixed. It is produced by direct compression molding, or it is prepared by adding mineral yeast and other mineral-rich materials and appropriate additives such as lubricants to the granules produced in advance and mixing them evenly, followed by compression molding.

Tablets or confectionery are plain tablets, coated tablets, sugar-coated tablets, multilayer tablets, dry-coated tablets, produced as described above,
Effervescent tablets, chewable tablets, buccal tablets, sublingual tablets, adhesive tablets,
It includes all tablets or confectionery such as troche tablets, dissolution tablets, reagent tablets, etc., and is not affected by its shape and weight.

In the case of granules, mineral yeast and other mineral-rich materials and excipients, binders, disintegrants or other suitable additives are uniformly mixed and granulated by a suitable method. After that, it is obtained by sizing to an appropriate particle size.

In the case of hard capsules, for example, mineral yeast and other mineral-rich materials can be used as they are, or those in which excipients, binders, disintegrating agents or other suitable additives are evenly mixed can be used in a suitable method. After forming into granules, a suitable additive such as a lubricant is added to fill capsules. Alternatively, a suitable additive such as a lubricant may be added to the mineral yeast and other high mineral content materials, and the mixture may be used as it is, or an excipient, a binder, a disintegrant or other suitable additive may be uniformly mixed. It is produced by directly filling capsules, or by adding mineral yeast and other mineral-rich materials and appropriate additives such as lubricants to the pre-prepared granules and mixing them evenly, and then filling capsules. The hard capsules of the present invention are all capsules produced as described above, and are not affected by the shape, size and material.

In the case of soft capsules, the above minerals in powder or granules are coated and molded with a general capsule base such as gelatin or a mixture of gelatin and glycerin. Specifically, it is obtained by diluting the minerals with an oily liquid and filling the capsule base. If necessary, a wax may be added for the purpose of preventing separation in the soft capsule, or the above-mentioned inactive ingredient, lecithin or the like may be added. The oily liquid in the present invention, wheat germ oil, salad oil, grape seed oil, olive oil, safflower oil, perilla oil, peanut oil, sesame oil,
Medium chain fat triglyceride, borage oil, soybean oil, DHA, E
Any ordinary oil used for food such as PA, liver oil, avocado oil, evening primrose oil, egg yolk oil, rice oil, octacosal, and propolis may be used. The wax in the present invention, beeswax, sucrose fatty acid ester, glycerin fatty acid ester, sorbitan fatty acid ester, propylene glycol fatty acid ester, rapeseed hydrogenated oil, safflower hydrogenated oil, palm hydrogenated oil, sitosterol, stigmasterol, All waxes that can be used in the food industry and pharmaceutical industry such as campesterol, brassicasterol, cocoa butter powder, carnauba wax, rice wax, wax and paraffin.

The food composition of the present invention can be formed into a pharmaceutical formulation as follows, for example.

After uniformly mixing the mineral yeast with other high mineral content materials and inactive ingredients, the binding solution is 3-40 parts by weight, preferably 4-35 parts by weight, per 100 parts by weight of the mixed powder. Particularly preferably, the mixture is added at a ratio of 5 to 30 parts by mass, granulated, dried, and then molded. If the amount of the binding solution added to the mixed powder of the mineral yeast and other high-mineral-content materials and inactive ingredients is less than 3 parts by mass with respect to 100 parts by mass of the mixed powder, the solvent will be added to the entire mixed powder. It is not permeated, and the high mineral content materials aggregate and separate, making uniform granulation difficult. Further, if the addition amount of the binding solution exceeds 40 parts by mass with respect to 100 parts by mass of the mixed powder, the mixed powder of the high mineral content material and the inactive component may cause blocking during granulation. Therefore,
The addition amount of the binding solution is preferably 3 to 40 parts by mass with respect to 100 parts by mass of the mixed powder of the mineral-rich material and the inactive component.

As the granulation method, a wet granulation method is suitable,
Specifically, the fluidized bed granulation method, the stirring granulation method, the extrusion granulation method, the crushing granulation method, the rolling granulation method and the like are effective. In the fluidized bed granulation method, the fluidized powder is granulated by spraying the binding liquid onto the fluidized powder in a fluidized bed granulator. In the stirring granulation method, powder is mixed, kneaded and granulated simultaneously in a closed structure by rotating a stirring blade at a high speed in a mixing tank while adding a binding solution. In the extrusion granulation method, the wet mass kneaded by adding the binding solution is forcedly extruded from a screen having an appropriate size by a screw type or basket type method. In the crushing and granulating method, the wet mass kneaded by adding the binding solution is sheared and ground by a rotary blade of a granulator, and the centrifugal force ejects it from the outer peripheral screen for granulation. In the rolling granulation method, the raw material powder that has been drawn to the outer wall by the centrifugal force of the rotating rotor rolls by the air blown up from the slit, and at this time the binding liquid sprayed from the spray gun creates a snowball type. Granulation is performed by growing spherical granules having a uniform particle size.

The granulated material can be dried by hot air heating type (shelf drying, vacuum shelf drying, fluidized bed drying), conduction heat transfer type (flat pan type,
Any method such as a shelf box type, a drum type) or freeze-drying can be used. In the hot air heating type, the material and hot air are brought into direct contact with each other, and at the same time, the evaporated water is removed. In the conductive heat transfer type, the material is indirectly heated through the heat transfer wall. In freeze-drying, the material is frozen at -10 to -40 degrees and then warmed under high vacuum (2-0.1 Torr) to sublime and remove water.

The food composition of the present invention comprises manganese yeast and copper.
Yeast, molybdenum yeast, zinc yeast, selenium yeast, chromium
Excellent yeast containing yeast and dolomite, heme iron, and seaweed
A lal-containing food composition is provided. In addition, shell powder, iron
Blending yeast, magnesium yeast, iodine yeast, etc.
Allows you to take minerals in good balance
A food composition is provided.

Further, the mineral yeast of the present invention and other mines
Improves the absorption rate of these minerals for materials with a high content of Ral
Vitamins for the purpose of improving health and maintaining and improving health.
C, vitamin B₆, Vitamin B₁₂, Folic acid, vitamin D
_Three, Vitamin E, vitamin K _Two, Isoflavone, casei
Phosphopeptide, lactose, sucrose, lactof
Formulation of erythrin, lysine, arginine, albumin, etc.
be able to.

By ingesting the food composition of the present invention, it is possible to improve and maintain health including anemia improvement and fatigue recovery, and it is also useful for preventing lifestyle-related diseases.

[0035]

EXAMPLES Examples of the present invention will be shown below, but the present invention is not limited thereto. In the examples, a fluidized bed granulation method was used as the granulation method, and water was used as the binding liquid at that time. A fluidized bed drying method was adopted as the drying method. Example 1 (tablet) By the formulation shown in Table 1, according to the following method,
Tablets were produced.

Raw materials other than vegetable oil and fat powder are put into a fluidized bed granulator (manufactured by Paulec), and water is mixed while being fluidized.
After adding 15 parts by mass to 00 parts by mass, the product was dried at 80 ° C. for 30 to 40 minutes so that the loss on drying was 5% or less. After drying, vegetable oil and fat powder was mixed, and the mixture was sized with a sieve (16 mesh) and then tableted. (Tabletting machine: rotary tableting machine, rotation speed: 30 rotations, tablet weight:
(340 mg, tableting pressure: 1000 kg)

[0037]

[Table 1] [Monitor test]

Using the tablets obtained in Example 1, ten women with anemia (people whose blood pigment content was less than 12 g / dL) were fed 6 tablets daily for 3 months, and a monitor test was conducted. . Regarding evaluation, improvement of anemia (hemoglobin level in blood ≧ 12 g / d
L) and improvement of feeling of fatigue (by the questionnaire by the self-filling method, each panelist selected the answer from among improved, normal, and deteriorated).

In the item of improvement of anemia, 7 persons were improved,
In the item of improvement of feeling of fatigue, 4 persons answered that they improved. There were 0 respondents who answered that they had worsened or worsened.

As can be seen from these results, the administration of the food composition of the present invention has the effects of improving anemia and relieving fatigue.

[0041]

INDUSTRIAL APPLICABILITY According to the present invention, a mineral-containing food composition having excellent absorbability of minerals is provided to improve anemia and fatigue.
Effect of labor recovery is obtained, by further compounded with other mineral-rich food material, mineral-containing food composition well-balanced blending various minerals are provided.

Claims (3)

(57) [Claims] 1. A food composition having an anemia improving effect and a fatigue recovering effect, which comprises at least manganese yeast as a source of manganese, copper, molybdenum, zinc, selenium and chromium,
0.1-25% by mass of mineral yeast consisting of copper yeast, molybdenum yeast, zinc yeast, selenium yeast, and chrome yeast, 40% by mass or more of dolomite, 10% by mass or more of heme iron,
A food composition comprising 1 to 10% by mass of one or more dry seaweeds selected from brown algae and red algae. 2. Manganese yeast, copper yeast, molybdenum yeast,
The food composition according to claim 1, which comprises 1 to 2 mass% each of zinc yeast, selenium yeast, and chromium yeast. 3. The food composition according to claim 1 or 2, wherein the food is in the form of tablets, confectionery, granules, hard capsules or soft capsules.