JP2761440B2 - Method and apparatus for performing R-f Ablation - Google Patents

Method and apparatus for performing R-f Ablation

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JP2761440B2
JP2761440B2 JP7507576A JP50757695A JP2761440B2 JP 2761440 B2 JP2761440 B2 JP 2761440B2 JP 7507576 A JP7507576 A JP 7507576A JP 50757695 A JP50757695 A JP 50757695A JP 2761440 B2 JP2761440 B2 JP 2761440B2
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catheter system
ablation catheter
ablation
catheter body
electrode
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JPH09500810A (en
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ホーイ,マイケル・エフ
ミューリアー,ピーター・エム・ジェイ
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メドトロニック・インコーポレーテッド
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Description

【発明の詳細な説明】 発明の背景 本発明は、心臓手術用の装置の分野に関し、更に詳細には、心臓組織のR−Fアブレーショ(ablation、表皮剥脱)を行うための装置に関する。 DETAILED DESCRIPTION OF THE INVENTION BACKGROUND OF THE INVENTION The present invention relates to the field of devices for cardiac surgery, and more particularly, cardiac tissue R-F Aburesho (ablation, abrasions) relates to a device for performing.

本発明は、心臓の心房及び心室が極めて速い拍動を示す頻拍不整脈の治療に関する。 The present invention relates to the treatment of tachycardia arrhythmias atrial and ventricle of the heart exhibits a very fast beat. 特に、本発明は、心臓組織内の異所性病巣(ectopic foci)により、又は心臓組織内の迷走状態経路(aberrant condition pathway)の存在による頻拍の治療に関する。 In particular, the present invention is the ectopic foci in cardiac tissue (ectopic foci), or treatment related tachycardia due to the presence of stray states pathways within the cardiac tissue (aberrant condition pathway).

異所性病巣又は迷走状態経路を有することが確認さた心臓組織を破壊することによって頻泊を治療するための療法が開発された。 Therapy for treating Shikihaku by destroying cardiac tissue was confirmed to have ectopic foci or stray state path is developed. 前記エネルギ又は他の形態のエネルギを加えて望ましからぬ心臓組織を破壊することを含む種々の方法がとられた。 Various methods involves disrupting the energy or other forms undesirable cardiac tissue by adding energy was taken. 心臓組織のアブレーションは、 Ablation of heart tissue,
例として、無線周波数電流、マイクロ波エネルギ、熱、 As an example, a radio-frequency current, microwave energy, heat,
電気パルス、クライオサーミー(cryothermy)、及びレーザーによって行われた。 Electrical pulses, cryo Sir Me (cryothermy), and was conducted by a laser. 現在では、非切開心臓(clos At present, non-incision heart (clos
ed heart)に挿入したカテーテルによって実施できるアブレーション術に関し、R−Fエネルギを使用したアブレーションが恐らく最も広く実施されている。 Relates ablation procedure which can be performed by inserting the catheter ed heart), ablation using R-F energy is perhaps the most widely practiced.

多くのR−Fアブレーションカテーテルは、心臓の心内膜と接触するようになった電極を使用し、場合によっては、米国特許第5,083,565号におけるように、心内膜に侵入し、心筋に進入するようになっている。 Many R-F ablation catheters, using electrodes intended to come into contact with the endocardium of the heart, in some cases, as in U.S. Pat. No. 5,083,565, penetrate the endocardium and enter the myocardium It has become way. 一般的には、R−Fアブレーションカテーテルは、電極の直ぐ近くの心臓内膜及び心筋の内層を含む心臓組織の小さな病変を誘導する上で有効である。 In general, R-F ablation catheters are effective to induce small lesions in heart tissue including the inner layer of the immediate vicinity of endocardial and myocardial electrodes. しかしながら、医学会は、頻拍と関連した心臓組織を効果的にアブレーション処置するのに必要なR−Fエネルギ(焼灼)の適用数を少なくするため、大きな病変をつくりだす装置が望ましいと表明している。 However, the medical community, in order to reduce the number of applications of R-F energy required to effectively ablate treating cardiac tissue associated with tachycardia (cauterization), expressed as produce large lesions device is desirable there.

R−Fアブレーションは、電極と接触した組織を、組織の抵抗に誘導電流を流すことによって加熱する。 R-F ablation, the tissue in contact with the electrode is heated by passing an induction current to the resistance of the tissue. 実際の加熱の程度は、予期できないところがある。 The extent of actual heating, there is something that can not be anticipated. しかしながら、温度は、R−F信号の持続時間及び振幅が増大するに従って高くなる傾向がある。 However, the temperature is high tends accordance duration and amplitude of the R-F signal is increased. 所定の点を越えて組織を加熱すると、組織の剥離や炭化を引き起こし、結果的に、R−F電極と帰還電極との間のインピーダンスを高くし、そのため、加熱プロセスが停止し、場合によっては、炭化した組織に電極がくっついてしまう。 Heating the tissue beyond a certain point, causes peeling or carbonization of tissue, consequently, to increase the impedance between the R-F electrode and the return electrode, therefore, the heating process is stopped, in some cases , the electrodes will stick to the charred tissue. この現象に対する一つの方策は、電極の温度を設定されたパラメータに維持するようにR−F信号を変調するためのフィードバック制御と関連した熱電対をアブレーション電極内に設けることである。 One way for this phenomenon is to provide a thermocouple associated with feedback control to modulate the R-F signal to maintain the set temperature of the electrode parameters within the ablation electrode. 一つのこのようなシステムは、 One such system is,
米国特許第5,122,137号に開示されている。 It is disclosed in U.S. Patent No. 5,122,137.

発明の概要 本発明は、R−Fアブレーションの一貫性及び効力を改善することに関し、R−Fアブレーションによって誘導された病変の全体としての大きさ及び程度を大きくすることに関する。 The present invention relates to improving the consistency and efficacy of R-F ablation, particularly to increase the size and extent of the entire lesions induced by R-F ablation. これらの目的は、アブレーションを行う場所の心筋にねじ込まれるようになった螺旋状電極を使用したアブレーションカテーテルによって行われた。 These objects are made by ablation catheter using a spiral electrode adapted to be screwed into the myocardium of the location where ablation.
螺旋状電極は、心内膜に挿入するための比較的真っ直ぐな即ち針状の電極と比べて大きな表面を提供し、更に、 Helical electrode provides a large surface as compared to relatively straight i.e. needle-like electrodes for insertion into the endocardium, further,
R−F信号の適用中にカテーテルの位置を安定させるのに役立つ。 During application of R-F signals serve to stabilize the position of the catheter. 更に、螺旋状電極を除去した後、本質的に出血が起こらない。 Furthermore, after removing the helical electrode, it does not occur essentially bleeding. そのため遺伝地図作製(mapping)を行うため及びアブレーションを行うために多くの位置に安全に配置することができる。 Therefore it is possible to securely positioned in a number of positions in order to perform and ablation for performing genetic cartography (mapping).

本発明の好ましい実施例における本発明の特徴は、リンゲル液のような、毒性のない、不整脈を引き起こさない、導電性の溶液を、R−Fエネルギの適用前及び適用中に電極の領域に入れることである。 Feature of the present invention in a preferred embodiment of the present invention, such as Ringer's solution, non-toxic, not cause arrhythmia, the conductive solution, putting the region of the electrode during the application before and the application of R-F energy it is. 螺旋状電極は、その好ましい実施例では、中空であり、導電性の溶液は、 Spiral electrodes, in its preferred embodiment, is a hollow, a solution of conductivity,
電極に設けられた一つ又はそれ以上の開口部を通して患部に適用される。 It applied to the affected area through one or more openings provided in the electrode. R−F信号の適用前に注入された導電性の溶液は、電極の近くの血液を移動させると考えられている。 The solution of the injected conductive prior to the application of R-F signal is believed to move near the blood of the electrode. リンゲル液の導電性は、例えば、血液(約3倍乃至4倍)や心筋(約7倍)よりも遥かに大きく、誘導電流の誘導に対する全体として抵抗は、電流の有効適用領域を広い領域に亘って拡げることによって、病変の大きさを拡張するのを助けるものと考えられる。 Conductive Ringer's solution, for example, blood (about 3-fold to 4-fold) and myocardial (approximately 7 times) much greater than the resistance as a whole for the induction of induced current, over the effective application area of ​​the current over a wide area by spreading Te believed to assist in expanding the size of the lesion. 焼灼中に導電性溶液を適用することによって、組織の過熱を回避し、R−F信号を長期間に亘って、通常は火傷や炭化を生じる点を越えて適用できる。 By applying the conductive solution during the ablation, to avoid overheating of the tissue, over the R-F signal to the long term, usually can be applied beyond the point of causing burns or carbonization. これらの要因は、両方とも、R−Fエネルギを特定の位置に適用することによってつくりだされた病変の全体としての大きさを増大するのに寄与するものと考えられる。 These factors are both believed to contribute to increase the size of the entire lesions created by the applying R-F energy to a specific location.

図面の簡単な説明 第1図は、本発明による改良されたR−Fアブレーション法を実行するようになったカテーテルの平面図である。 BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a plan view of a catheter adapted to perform the R-F ablation, which is improved according to the present invention.

第2図は、第1図に示すカテーテルの先端の断面図である。 Figure 2 is a cross-sectional view of the distal end of the catheter shown in Figure 1.

第3図、第4図、及び第5図は、第1図及び第2図に示すカテーテルの螺旋状電極の変形例を示す部分断面側面図である。 Figure 3, Figure 4, and Figure 5 is a partial cross-sectional side view showing a modification of the spiral electrode catheter shown in FIGS. 1 and 2.

第6図は、R−Fエネルギの螺旋状電極への適用前及び適用中に導電性溶液を投与するための関連した装置の概略図である。 6 is a schematic diagram of a related device for administering the conductive solution during the application before and application to the helical electrode of the R-F energy.

好ましい実施例の詳細な説明 第1図は、本発明に従ってR−Fアブレーションを行うように特別に設計されたカテーテルの平面図である。 DETAILED DESCRIPTION OF THE PREFERRED Figure 1 embodiment is a plan view of a catheter specifically designed to perform R-F ablation according to the present invention.
カテーテルは、絶縁外シース12を持つ細長いカテーテル本体10を含む。 The catheter includes an elongated catheter body 10 having an insulating outer sheath 12. シースは、ポリウレタン、テフロン、又は他の生体親和性プラスチックでつくられているのがよい。 Sheath, polyurethane, teflon, or it is what is made of other biocompatible plastic. 螺旋状中空電極14がカテーテルの先端に配置されており、この電極は、カテーテルの長さに亘って延びる内部チューブ30の先端に連結されている。 Helical hollow electrode 14 is arranged at the distal end of the catheter, the electrode is connected to the distal end of the inner tube 30 extending over the length of the catheter. カテーテルの基端には継手16が配置されており、この継手にはルエルロック18が連結されている。 The proximal end of the catheter is disposed fitting 16, Ruerurokku 18 is connected to this joint. ルエルロック(luer lock)1 Ruerurokku (luer lock) 1
8は、内部チューブ30の基端に連結されている。 8 is connected to the proximal end of the inner tube 30. カテーテルがルエルロック(luer lock)22に対して回転できるように旋回取り付け対20がルエルロック18に取り付けられている。 Catheter swivel mounted pair 20 for rotation relative to Ruerurokku (luer lock) 22 is attached to Ruerurokku 18. ルエルロック22は、リンゲル液のような導電性の流体の供給源に連結されるようになっており、電極14が心臓組織にねじ込まれた状態で、カテーテル及び電極14を通してリンゲル液を供給することができる。 Ruerurokku 22 is adapted to be connected to a source of conductive fluid such as Ringer's solution, with the electrodes 14 is screwed into the heart tissue, it is possible to supply Ringer's solution through the catheter and the electrode 14. 電極14に接続された電気コネクタ24が継手16から出ており、R−Fエネルギを心臓組織に加えるのに電極14を使用できる。 Electrical connector 24 connected to the electrode 14 are out of the fitting 16, the electrodes 14 can be used for adding R-F energy to heart tissue. 更に、電極14は、心臓内の電気曲線図の計測や心臓の歩調取り即ちペーシングに適した低エネルギのパルスを加えることによって心臓組織のペーシングを行うといった他の関連した機能についても使用できる。 Furthermore, the electrode 14 may also be used for other related functions such as performing a pacing cardiac tissue by applying a pulse of low energy which is suitable for measurement and cardiac pacing i.e. pacing electrical curves within the heart. 使用に当たっては、所望のアブレーション位置までカテーテルを前進させる。 Use In advances the catheter to the desired ablation location. この位置は、好ましくは、R−Fアブレーション術で現在使用されている心臓遺伝地図作製と同様の方法で心臓遺伝地図作製を行うことによって予め確認してある。 This position, Aru preferably sure in advance by performing cardiac genetic map prepared in cardiac genetic map prepared similar to the method currently used in R-F ablation procedures. カテーテルは、例えばバッジャー等に賦与された米酷特許第5,030,204号に開示された操舵可能な即ち案内可能なカテーテルに次々に入れることによって、又は例えばイスナーに賦与された米国特許第5,10 Catheter, for example, such as by placing one after the other steerable That guidable catheter disclosed in US severe Patent No. 5,030,204 endowed in Badger, or for example, US Patent endowed in isnâ the 5,10
4,393号の固定形体案内カテーテルによって所望の位置まで案内できる。 By 4,393 No. of fixed configuration guide catheter can be guided to a desired position. これらの特徴について触れたことにより、両特許に開示されている内容は本明細書中に組み入れたものとする。 By touching on these features, the contents disclosed in both patents shall be incorporated herein. 変形例では、1993年3月18日に発行されたPCT特許出願第WO93/04724号に開示されているような変形自在のスタイレットによって、又はギャンベール等に賦与された米国特許第5,060,660号に開示されているような変形自在の案内ワイヤによって、カテーテルを心臓内の所望の場所まで前進させることができる。 In a variant, disclosed in the deformable stylet as disclosed in PCT Patent Application No. WO93 / 04 724, issued March 18, 1993, or U.S. Pat. No. 5,060,660 endowed in such Gyanberu the deformable guide wire as is, the catheter can be advanced to a desired location within the heart. これらの特許について触れたことにより、両特許に開示されている内容は本明細書中に組み入れたものとする。 By touching these patents, the contents disclosed in both patents shall be incorporated herein. 中空電極14は、所望の位置に配置されると、カテーテル本体を回転させることによって心臓組織にねじ込まれる。 The hollow electrode 14, when placed in the desired position, is screwed into heart tissue by rotating the catheter body. カテーテル本体内のトルクケーブルは、カテーテルの基端から中空電極14までトルクを1:1で伝達する。 Torque cable within the catheter body, the torque from the proximal end of the catheter to the hollow electrode 14 1: transmitting at 1.

所望の位置まで前進したとき、ルエルロック22をリンゲル液加圧供給源に連結する。 When it advanced to a desired position, connecting the Ruerurokku 22 in Ringer pressurized supply. 適当な供給源を第6図と関連して以下に詳細に論じる。 A suitable source in connection with FIG. 6 discussed in detail below. しかしながら、本発明の目的について、リンゲル液を大気圧で毎分1cc送出できるリンゲル液供給源が適当であることがわかっている。 However, for the purposes of the present invention, Ringer's solution supply source capable min 1cc sends Ringer's solution at atmospheric pressure has been found to be suitable.
リンゲル液の送出は、アブレーションが行われるべき組織に電極14をねじ込む前、又はねじ込むときに開始しなければならない。 Ringer's solution delivery is prior to screwing the tissue to the electrode 14 to the ablation is performed, or must be started when screwing. 動物実験では、本発明者は、R−Fエネルギを送り出す前にリンゲル液を二分間に亘って送出すると、大きいが制御された規則的な病変をつくりだすのを補助するということがわかった。 In animal experiments, the present inventors, when sent over the Ringer's solution in two minutes before sending the R-F energy, it has been found that large, but to assist in creating a regular lesions controlled.

電極を配置し、リンゲル液を所望の期間に亘って投与した後、電気コネクタ24を、商業的に利用可能な種類の、電気凝固組織の切断に使用されるR−F電気外科電源に接続する。 The electrodes are arranged, after the Ringer's solution was administered over a desired period of time, to connect the electrical connector 24, commercially available types, the R-F electrosurgical power source used to cut the electrocoagulation tissue. 本発明者は、ブレンドトーム(Blendtom The present inventors have, blend storm (Blendtom
e)の商標の電気外科発電機第755型、凝固設定番号第7 Trademark of electrosurgical generator # 755 type e), coagulation setting number 7
番、切断設定番号第1番を使用した。 Turn, was using the No. 1 cutting setting number. これらの設定では、大きな制御された病変をつくりだすのに、R−Fエネルギを、長期間、例えば一分間位に亘って使用できる。 These settings to produce a large control lesion, the R-F energy, a long period of time, for example can be used over a minute position. しかしながら、期間をこれよりも長くしてもよいし短くしてもよく、二十秒以下の期間をカウンタに表示でき、このような短いR−F適用時間では、リンゲル液の冷却効果により、実際には、病変の効果的な大きさが小さくなるということがわかっているためである。 However, may be shortened may be longer than this period can display period twenty seconds or less to the counter, in such a short R-F application times, the cooling effect of the Ringer's solution, actually is because has been found that effective size of the lesion is small.

R−Fアブレーションを行った後、電極を心臓ペースメーカーに接続でき、ペーシング閾値を計測する試みにおいて、心臓ペーシングエネルギを病変場所に送ることができる。 After R-F ablation, the electrode can be connected to a heart pacemaker, in an attempt to measure the pacing threshold may send cardiac pacing energy to the lesion site. ペーシング閾値は、種々のエネルギレベルのペーシングパルスを送出することによって、例えばパルスの振幅又は幅を変化させて心臓組織を脱分極するのに有効な最小エネルギレベルを決定することによって計測できる。 Pacing threshold by delivering pacing pulses of different energy levels can be measured by determining the effective minimum energy level, for example, for varying the pulse amplitude or width to depolarize the cardiac tissue. 本発明者は、病変が比較的同構造であると仮定すると、ペーシング閾値が大きければ大きい程、病変の大きさが大きいと考えているる。 The present inventors, assuming lesion is relatively the same structure, the greater the pacing threshold, consider the magnitude of the lesion volume. このように、病変の全体としての大きさを概算するのに電極14を使用できる。 Thus, the electrode 14 can be used to estimate the size of the entire lesion.
更に、電極は、頻拍が持続するかどうか及び頻拍と関連した迷走状態又は異所性活性(ectopic activity)に電極近傍の組織が関与しているかどうかを決定するのを助けるカップルドEKG監視装置(coupled EKG monitoring Furthermore, the electrode-coupled EKG monitoring to assist in determining whether tachycardia associated with and whether tachycardia persists the vagus state or ectopic activity (ectopic activity) in the vicinity of the electrode structure is involved apparatus (coupled EKG monitoring
equipment)であるのがよい。 Good in the range of equipment).

電極14の螺旋形体は、アブレーション電極と関連して特に有利であると考えられる。 Spiral configuration of the electrode 14 is believed to be particularly advantageous in connection with the ablation electrode. 電極が、血流の外で、心臓組織内にねじ込まれ、この組織内に完全に配置されるため、R−Fエネルギは、組織自体に限定される。 Electrodes, outside the bloodstream, is screwed into the heart tissue, to be positioned entirely within this organization, R-F energy is limited to the tissue itself. 心内膜と接触するだけであるため、加えられたエネルギの大部分が電極の場所に隣接した心臓内の血液中に散逸する従来のR−Fアブレーション電極とは異なる。 Since it only contacts the endocardium, the majority of the applied energy is different from the conventional R-F ablation electrodes to dissipate in the blood within the heart adjacent to the location of the electrodes. 更に、血流に加わえられたR−Fエネルギは、電極近くの血液を凝結させ、電極が凝血により開路する(clots breaking Moreover, R-F energy is e Kuwawa the bloodstream, agglomerated electrodes near the blood, the electrode is open by coagulation (Clots breaking
loose of electrode)危険が大きくなる。 loose of electrode) danger increases.

更に、螺旋状の電極は、上文中で引用したパリンスの特許で提案された針状電極と比べて表面積がかなり大きく、また、R−Fエネルギを加えているときにカテーテルを確実に固定するのに役立つ。 Furthermore, spiral electrode is much larger surface area than the proposed needle electrode in patent Parinsu cited hereinabove, also, to reliably secure the catheter when it is added to R-F energy to help. 更に、真っ直ぐな中空電極を使用した場合には、電極が、液圧によってその挿入場所から後方に抜けてしまうが、電極が螺旋錠であるため、電極を通して加えられた導電性の溶液によって、 Furthermore, when using straight hollow electrode, electrodes, but fall out backward from the insertion location by a hydraulic, because the electrode is spiral tablet, with a solution of a conductive applied through the electrodes,
電極が、液圧によってその挿入場所から後方に引き抜けることがない。 Electrodes, never pulled out backward from the insertion location hydraulically. 更に、螺旋状電極が構成する細長い行路は、導電性の流体が針に沿って漏れ、心臓組織の外に出る可能性を小さくする。 Furthermore, the elongated path helical electrode constitutes the conductive fluid leakage along the needle, to reduce the possibility that out of the heart tissue.

第2図は、第1図に示すカテーテルの端部の断面図である。 Figure 2 is a cross-sectional view of an end portion of the catheter shown in Figure 1. この図では、螺旋状電極14は内腔26を有し、この内腔がチューブ30の内腔と連通しているということがわかる。 In this figure, the helical electrode 14 has a lumen 26, the lumen can be seen that communicates with the lumen of the tube 30. チューブ30は、カテーテルの基端まで延びており、上文中に論じたような、ルエルロック18と完全に連通している。 Tube 30 extends to the proximal end of the catheter, as discussed above, is in fluid fully coupled with Ruerurokku 18. チューブ30は、ポリイミド製チューブ又はステンレス鋼製チューブでできているのがよい。 Tube 30, it is preferable made of polyimide tubing or of stainless steel tubing. 本発明では、ステンレス鋼製チューブは、電極14を電気コネクタ24に接続し、カテーテルの全体としての導電性を高める追加の導体として役立つ。 In the present invention, stainless steel tubing, connect the electrodes 14 to the electrical connector 24, it serves as an additional conductor to increase the conductivity of the whole catheter. ポリイミド製チューブを使用すると、カテーテルの全体としての導電性が小さくなるが、可撓性が幾分高くなり、場合によっては有利である。 With polyimide tube, but the conductivity of the overall catheter is reduced, flexibility is somewhat higher, in some cases it is advantageous. カテーテルを脈管系を通して電極場所まで通過させるとき、可能であれば、リンゲル液の一定の流れをチューブを通して電極14に加えることが推奨される。 When passing the catheter to the electrode location through the vascular system, if possible, it is recommended to add a constant flow of Ringer's solution to the electrode 14 through the tube. この場合、リンゲル液の流れは、チューブ30の内腔の開存性の維持を助け、心筋内に前進させるときに電極の出口ポートが塞がらないようにする。 In this case, Ringer's solution flow helps maintain the patency of the lumen of the tube 30, so that the outlet port of the electrodes are not Fusagara when advancing into the myocardium.

チューブ30は、逆方向に巻いた二つのコイル32及び34 Tube 30, two coils 32 and 34 wound in the opposite direction
によって取り囲まれており、トルクケーブルを構成する。 Is surrounded by, it constitutes a torque cable. 本発明者が使用した特定の装置の場合には、ミネソタ州チャカスのレーク・リージョン製造社が製造したトルクケーブルを使用し、このトルクケーブルは、米国特許第5,165,421号に記載されている。 If the particular device that the present inventor has used, using a torque cable Lake Region manufacturer Minnesota mock is prepared, the torque cable is described in U.S. Patent No. 5,165,421. 同特許について触れたことにより、その特許に開示されている内容は本明細書中に組み入れたものとする。 By touching the same patent, what is disclosed in the patent shall be incorporated herein. コイル32及び34は、導体としても役立つ。 Coils 32 and 34, also serves as a conductor. 図示のように、チューブ30は、金属コイル32及び34と螺旋状電極14との間にある。 As shown, the tube 30 is between the metal coils 32 and 34 and helical electrode 14. しかしながら、ポリイミド製チューブを使用した場合には、コイル32及び34は、単なる導体として役立ち、かくして、溶接、ハンダ付け、又は機械的相互連結によって電極14に電気的に接続される。 However, when using the polyimide tube coils 32 and 34, it serves as a mere conductor, thus, welding, soldering, or is electrically connected to the electrode 14 by mechanical interlocking. 絶縁スリーブ12は、カテーテルに滑らかな外側を提供するのに役立ち、更に、金属コイル Insulating sleeve 12 serves to provide a smooth outer catheter, further, the metal coil
32及び34をカテーテルの長さに沿って絶縁するのに役立つ。 32 and 34 along the length of the catheter helps to insulate.

第3図、第4図、及び第5図は、第2図に示す螺旋状電極の変形例を示す。 Figure 3, Figure 4, and Figure 5 shows a variant of the helical electrode illustrated in Figure 2. 第2図の電極は、中空チューブからなり、単一の出口レポートがその先端に配置されている。 Electrode of the second figure, a hollow tube, a single outlet report is arranged at the tip. 第3図に示す電極36は、螺旋状電極の長さに沿ってリンゲル液を出すことができる追加の出口ポート38、4 Electrode 36 shown in FIG. 3, the additional outlet port can issue Ringer's solution along the length of the spiral electrode 38,4
0、及び42が設けられていることを除き、電極14と同じである。 0, and 42 except that is provided is the same as the electrode 14. ポートは、レーザーを使用して穿孔されているのがよく、電極36の周囲に亘って及び電極36の長さに沿って任意の所望の方法で間隔を隔てられているのがよい。 Port may have what is drilled using a laser, it is preferable along the length of the around the circumference of electrode 36 and electrode 36 are spaced in any desired manner. リンゲル液を均等に分配し且つ分散するため、ポートは、好ましくは、電極の全周に亘って間隔が隔てられているのが望ましいと考えられている。 To evenly distribute to and dispersed Ringer's solution, port, preferably, it has been considered a desirable interval over the entire circumference of the electrodes are separated.

第4図に示す電極44は、電極14と対応する螺旋状電極の第2の変形例であり、電極の基端部分を覆う絶縁スリーブ46が加えられている。 Electrode 44 shown in FIG. 4 is a second modification of the electrode 14 corresponding helical electrode, an insulating sleeve 46 covering the proximal portion of the electrode is added. スリーブ46は、R−Fエネルギが電極の先端部分だけで適用されるようにする。 The sleeve 46, R-F energy is to be applied only at the tip portions of the electrodes. 随意であるが、図3に示すポート38、40、及び42と対応する追加の出口ポートを電極44と関連して使用してもよい。 Is a optionally may be used in connection with the additional outlet port corresponding to the port 38, 40, and 42 shown in FIG. 3 and the electrode 44.
これらの追加の出口ポートは、電極44の露呈された絶縁されていない部分に限定されるか或いは電極44の全長に亘って設けられている。 These additional exit ports are provided over the entire length of the or electrodes 44 are limited to the exposed insulating that are not part of the electrode 44.

第5図に示す電極48は、全体に電極14と対応する第3 Electrode 48 shown in Fig. 5, third corresponding to the entire and the electrode 14
の変形例である。 Modification of a. しかしながら、この例では、電極48の先端に熱電対50が設けられている。 However, in this example, the thermocouple 50 is provided on the tip of the electrode 48. 熱電対の導線52及び Conductor 52 of the thermocouple and
54は、電極48の内腔を通って後方に延びており、これらの導線は、上文中で引用したレノックス等の特許に記載されているように、電極に加えられる電力のフィードバック制御で使用するため、電極先端の温度を監視するのに使用される。 54 extends rearwardly through the lumen of the electrode 48, these conductors, as described in patents such as Lenox cited hereinabove, for use in feedback control of the power applied to the electrode Therefore, it is used to monitor the temperature of the electrode tip. 熱電対の導線52及び54の一方だけが絶縁され、他方は、電極48の内部に接続される。 Only one of the conductors 52 and 54 of the thermocouple is insulated, the other is connected to the internal electrode 48. 第5図の電極を使用するためには、電極48に接続されていない熱電対の導線に接続できるようにするため、追加の電気コネクタを第5図に示す実施例に加えなければならない。 To use the electrode of FIG. 5, in order to be able to connect to the conductors of the thermocouple that is not connected to the electrode 48, it must be added to the embodiment shown an additional electrical connector in FIG. 5. 変形例では、熱電対の両導線を絶縁する。 In a variant, it insulates both conductors of the thermocouple. この場合には、 In this case,
熱電対の一本の導線に各々接続された二つの追加の電気コネクタを装置の基端に設ける必要がある。 It is necessary to provide the proximal end of the two additional electrical connector device which is respectively connected to one conductor of the thermocouple. 熱電対50が電極48の内腔の先端開口部を効果的に塞ぎ、そのため、 Thermocouple 50 is effectively blocks the distal opening of the lumen of the electrode 48, therefore,
リンゲル液が側ポート56、58、及び60からしか分配されないということに着目されたい。 Want Ringer's solution is focused on the fact that not only dispensed from the side ports 56, 58, and 60.

第6図は、第1図に示すカテーテルと関連して使用できるリンゲル液加圧供給源を示す。 Figure 6 shows a Ringer pressurized supply that may be used in connection with the catheter shown in Figure 1. ブロック・メディカル社が商業的に製造し、「ホンムポンプ」の商標で販売しているリザーバ100が設けられている。 Block Medical Inc. commercially manufactured, a reservoir 100 which is sold under the trademark "Honmuponpu" are provided. リザーバにはリンゲル液が入っており、リンゲル液を一気圧の圧力でフィルタ104を介して流れ制御装置102に提供する。 The reservoir has entered Ringer's solution, providing a Ringer's solution through the filter 104 at a pressure of one atmosphere to the flow control device 102. 流れ制御装置102は、例えば、流れを毎分20滴又は1ccに制限する。 Flow control device 102, for example, to restrict the flow per minute 20 drops or 1 cc. 流れ制御装置102は、第2流れ制御要素104に連結されている。 Flow control device 102 is connected to the second flow control element 104. 第2流れ制御要素104は、本発明者が使用する実験装置において、流量を追加に調節できるようにする。 The second flow control element 104, in the experimental apparatus to which the present invention's use, to be able to adjust the flow rate added. 流れ制御要素104は、第1図に示すルエルロック2 Flow control element 104, Ruerurokku 2 shown in Figure 1
2に連結されており、これは、電極14(第1図参照)と流体連通しており、リンゲル液を電極に送出することができる。 2 is connected to, this electrode 14 and (first see figure) and in fluid communication, capable of delivering Ringer's solution to the electrode. R−F電気エネルギを提供するための電気外科発電機200が、機能を示すブロックの形体で示してある。 Electrosurgical generator 200 for providing R-F electrical energy is illustrated in the form of a block showing the function. この発電機は、電気コネクタ24及び接地プレート電極202(等縮尺でない)に接続されている。 The generator is connected to the electrical connector 24 and the ground plate electrode 202 (not to scale). この他の全ての要素は、第1図に示したものと対応する。 This all other elements, corresponding to those shown in Figure 1.

上掲の実施例は、カテーテルを前進させ所望の位置に位置決めするための第2要素(例えば、案内カテーテル又は案内ワイヤ)を必要とするが、上文中に開示した基本的な装置を、臨床研究で現在用いられているR−Fアブレーションカテーテルと同様の、それ自体が操舵可能であり即ち変形可能なカテーテルに組み込むこともできると考えられている。 EXAMPLE supra, the second element for positioning in a desired position to advance the catheter (e.g., guide catheter or guide wire) requires a, the basic apparatus disclosed hereinabove, clinical studies in believed may be incorporated into the R-F similar to the ablation catheter itself is steerable i.e. deformable catheters currently used. 同様に、商業的実施例において、 Similarly, in the commercial embodiment,
リンゲル液の流れを制御するための別の機構(例えば、 Another mechanism for controlling the flow of Ringer's solution (for example,
精密なポンプ)を使用できると考えられている。 It is believed that precise pump) can be used. 同様に、本発明者はリンゲル液を使用したが、これとは異なる流体を使用してもよい。 Similarly, the present inventor has been using Ringer's solution, it may use different fluids thereto. このように、上文中に論じた実施例は、限定的でなく例示の実施例であると考えられるべきである。 Thus, the embodiments discussed above are to be considered as illustrative examples, not limiting.

───────────────────────────────────────────────────── フロントページの続き (58)調査した分野(Int.Cl. 6 ,DB名) A61B 17/39 ────────────────────────────────────────────────── ─── of the front page continued (58) investigated the field (Int.Cl. 6, DB name) A61B 17/39

Claims (9)

    (57)【特許請求の範囲】 (57) [the claims]
  1. 【請求項1】基端部分と、先端部分と、長手方向の内腔とを有する、細長いカテーテル本体と、 前記カテーテル本体の先端部分に取り付けられ、かつ、 And 1. A proximal portion has a distal end portion, and a longitudinal lumen, the elongated catheter body is attached to the distal portion of the catheter body, and,
    前記カテーテル本体の前記内腔に連結された内腔を有する、身体組織に所望位置において侵入するための中空針と、 導電性流体を前記カテーテル本体の前記内腔に送出するため、前記カテーテル本体の内腔に連結された、導線性流体供給源と、 R−Fエネルギを前記所望位置に送出するため、前記カテーテル本体の前記先端部分に取り付けられた、導電性の電極表面と、 前記電極表面に接続されたR−F電気エネルギ源とを有し、 前記中空針は導電性を有し、前記電極表面は前記中空針の表面からなり、前記中空針は螺旋状の針からなることを特徴とする、アブレーションカテーテルシステム。 Having said lumen coupled to the lumen of the catheter body, for delivery and hollow needle to penetrate at a desired position in body tissue, the conductive fluid to said lumen of said catheter body, said catheter body coupled to the lumen, and lead fluid supply source, for delivering R-F energy to said desired position, the attached to the distal portion of the catheter body, and a conductive electrode surface, the electrode surface and a connected R-F electrical energy source, said hollow needle is conductive, the electrode surface is made from a surface of said hollow needle, said hollow needle and characterized by comprising a spiral needle to, ablation catheter system.
  2. 【請求項2】請求項1に記載のアブレーションカテーテルシステムにおいて、前記流体送出手段はリンゲル液を送出するための手段を有する、前記アブレーションカテーテルシステム。 2. A ablation catheter system according to claim 1, wherein the fluid delivery means comprises means for delivering Ringer's solution, the ablation catheter system.
  3. 【請求項3】請求項2に記載のアブレーションカテーテルシステムにおいて、前記導線性流体を送出するための手段は、前記導電性流体を収容するリザーバと、流体の流れを制御するための手段とを有する、前記アブレーションカテーテルシステム。 3. The ablation catheter system according to claim 2, means for delivering the wire fluid has a reservoir containing said conductive fluid, and means for controlling the flow of fluid the ablation catheter system.
  4. 【請求項4】請求項1に記載のアブレーションカテーテルシステムにおいて、前記カテーテル本体は、前記カテーテル本体に沿って長手方向に延在するトルク伝達ケーブルを有する、前記アブレーションカテーテルシステム。 4. A ablation catheter system according to claim 1, wherein the catheter body has a torque transmission cable extending longitudinally along said catheter body, the ablation catheter system.
  5. 【請求項5】請求項1に記載のアブレーションカテーテルシステムにおいて、前記カテーテル本体は、前記カテーテル本体に沿って長手方向に延在するトルク伝達ケーブルを有し、前記ケーブルは前記中空針と前記R−Fエネルギ源とに接続されている、前記アブレーションカテーテルシステム。 5. The ablation catheter system according to claim 1, wherein the catheter body has a torque transmission cable extending longitudinally along said catheter body, the cable is the said hollow needle R- It is connected to the F energy source, the ablation catheter system.
  6. 【請求項6】請求項1に記載のアブレーションカテーテルシステムにおいて、前記カテーテル本体は前記カテーテル本体に沿って長手方向に延在する導電性チューブを有し、前記チューブは前記中空針と前記R−Fエネルギ源とに接続されている、前記アブレーションカテーテルシステム。 6. The ablation catheter system according to claim 1, wherein the catheter body has a conductive tube extending longitudinally along said catheter body, wherein the tube and the hollow needle R-F It is connected to the energy source, the ablation catheter system.
  7. 【請求項7】請求項1に記載のアブレーションカテーテルシステムにおいて、前記カテーテル本体は、前記カテーテル本体に沿って延在するプラスチックチューブを有し、前記チューブは前記中空針と前記送出手段とに連結されている、前記アブレーションカテーテルシステム。 7. The ablation catheter system according to claim 1, wherein the catheter body has a plastic tube which extends along said catheter body, said tube is connected to said delivery means and said hollow needle and that the ablation catheter system.
  8. 【請求項8】請求項1に記載のアブレーションカテーテルシステムにおいて、前記アブレーションカテーテルシステムは、更に、電気信号を検出するための電気信号検出手段を有し、前記電気信号検出手段は前記電極表面に連結されている、前記アブレーションカテーテルシステム。 8. The ablation catheter system according to claim 1, wherein the ablation catheter system further comprises an electrical signal detection means for detecting an electrical signal, the electrical signal detection means coupled to the electrode surface It is, the ablation catheter system.
  9. 【請求項9】請求項1又は8に記載のアブレーションカテーテルシステムにおいて、前記アブレーションカテーテルシステムは、更に、刺激パルスを送出するための刺激パルス送出手段を有し、前記刺激パルス送出手段は前記電極表面に接続されている、前記アブレーションカテーテルシステム。 9. The ablation catheter system according to claim 1 or 8, wherein the ablation catheter system further includes a stimulation pulse delivery means for delivering the stimulation pulses, the stimulation pulse delivery means the electrode surface It is connected to, the ablation catheter system.
JP7507576A 1993-08-27 1994-07-25 Method and apparatus for performing R-f Ablation Expired - Lifetime JP2761440B2 (en)

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Families Citing this family (437)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6770071B2 (en) * 1995-06-07 2004-08-03 Arthrocare Corporation Bladed electrosurgical probe
US6896674B1 (en) 1993-05-10 2005-05-24 Arthrocare Corporation Electrosurgical apparatus having digestion electrode and methods related thereto
US6832996B2 (en) 1995-06-07 2004-12-21 Arthrocare Corporation Electrosurgical systems and methods for treating tissue
US5683366A (en) * 1992-01-07 1997-11-04 Arthrocare Corporation System and method for electrosurgical tissue canalization
US5697882A (en) 1992-01-07 1997-12-16 Arthrocare Corporation System and method for electrosurgical cutting and ablation
US6763836B2 (en) 1998-06-02 2004-07-20 Arthrocare Corporation Methods for electrosurgical tendon vascularization
US6159194A (en) * 1992-01-07 2000-12-12 Arthrocare Corporation System and method for electrosurgical tissue contraction
US6620155B2 (en) 1996-07-16 2003-09-16 Arthrocare Corp. System and methods for electrosurgical tissue contraction within the spine
US5586982A (en) * 1992-04-10 1996-12-24 Abela; George S. Cell transfection apparatus and method
US5370675A (en) * 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
US5743870A (en) * 1994-05-09 1998-04-28 Somnus Medical Technologies, Inc. Ablation apparatus and system for removal of soft palate tissue
US6805128B1 (en) 1996-10-22 2004-10-19 Epicor Medical, Inc. Apparatus and method for ablating tissue
US6840936B2 (en) * 1996-10-22 2005-01-11 Epicor Medical, Inc. Methods and devices for ablation
US6237605B1 (en) 1996-10-22 2001-05-29 Epicor, Inc. Methods of epicardial ablation
US6311692B1 (en) 1996-10-22 2001-11-06 Epicor, Inc. Apparatus and method for diagnosis and therapy of electrophysiological disease
US8709007B2 (en) 1997-10-15 2014-04-29 St. Jude Medical, Atrial Fibrillation Division, Inc. Devices and methods for ablating cardiac tissue
US6719755B2 (en) 1996-10-22 2004-04-13 Epicor Medical, Inc. Methods and devices for ablation
US7052493B2 (en) 1996-10-22 2006-05-30 Epicor Medical, Inc. Methods and devices for ablation
US6161543A (en) 1993-02-22 2000-12-19 Epicor, Inc. Methods of epicardial ablation for creating a lesion around the pulmonary veins
US7297145B2 (en) * 1997-10-23 2007-11-20 Arthrocare Corporation Bipolar electrosurgical clamp for removing and modifying tissue
US5921982A (en) * 1993-07-30 1999-07-13 Lesh; Michael D. Systems and methods for ablating body tissue
WO1995003843A1 (en) * 1993-07-30 1995-02-09 The Regents Of The University Of California Endocardial infusion catheter
US5980516A (en) * 1993-08-27 1999-11-09 Medtronic, Inc. Method and apparatus for R-F ablation
US5807395A (en) * 1993-08-27 1998-09-15 Medtronic, Inc. Method and apparatus for RF ablation and hyperthermia
US5431649A (en) * 1993-08-27 1995-07-11 Medtronic, Inc. Method and apparatus for R-F ablation
US6569159B1 (en) 1993-11-08 2003-05-27 Rita Medical Systems, Inc. Cell necrosis apparatus
US6059780A (en) 1995-08-15 2000-05-09 Rita Medical Systems, Inc. Multiple antenna ablation apparatus and method with cooling element
US6689127B1 (en) * 1995-08-15 2004-02-10 Rita Medical Systems Multiple antenna ablation apparatus and method with multiple sensor feedback
US5599346A (en) 1993-11-08 1997-02-04 Zomed International, Inc. RF treatment system
US6632221B1 (en) 1993-11-08 2003-10-14 Rita Medical Systems, Inc. Method of creating a lesion in tissue with infusion
US20080167649A1 (en) * 1994-08-12 2008-07-10 Angiodynamics, Inc. Ablation apparatus and method
US5536267A (en) 1993-11-08 1996-07-16 Zomed International Multiple electrode ablation apparatus
US6641580B1 (en) * 1993-11-08 2003-11-04 Rita Medical Systems, Inc. Infusion array ablation apparatus
US5865738A (en) * 1993-12-10 1999-02-02 Regents Of The University Of California Tissue viability monitor
US5458596A (en) * 1994-05-06 1995-10-17 Dorsal Orthopedic Corporation Method and apparatus for controlled contraction of soft tissue
US5735846A (en) * 1994-06-27 1998-04-07 Ep Technologies, Inc. Systems and methods for ablating body tissue using predicted maximum tissue temperature
US6113591A (en) * 1994-06-27 2000-09-05 Ep Technologies, Inc. Systems and methods for sensing sub-surface temperatures in body tissue
US5609151A (en) * 1994-09-08 1997-03-11 Medtronic, Inc. Method for R-F ablation
US5876398A (en) * 1994-09-08 1999-03-02 Medtronic, Inc. Method and apparatus for R-F ablation
US5551427A (en) * 1995-02-13 1996-09-03 Altman; Peter A. Implantable device for the effective elimination of cardiac arrhythmogenic sites
US5782771A (en) * 1995-04-17 1998-07-21 Hussman; Karl L. Dual, fused, and grooved optical localization fibers
US5688267A (en) * 1995-05-01 1997-11-18 Ep Technologies, Inc. Systems and methods for sensing multiple temperature conditions during tissue ablation
US6053912A (en) * 1995-05-01 2000-04-25 Ep Techonologies, Inc. Systems and methods for sensing sub-surface temperatures in body tissue during ablation with actively cooled electrodes
WO1996034570A1 (en) * 1995-05-01 1996-11-07 Ep Technologies, Inc. Systems and methods for obtaining desired lesion characteristics while ablating body tissue
US5800432A (en) * 1995-05-01 1998-09-01 Ep Technologies, Inc. Systems and methods for actively cooling ablation electrodes using diodes
US6322548B1 (en) 1995-05-10 2001-11-27 Eclipse Surgical Technologies Delivery catheter system for heart chamber
US7276063B2 (en) 1998-08-11 2007-10-02 Arthrocare Corporation Instrument for electrosurgical tissue treatment
US6224584B1 (en) 1997-01-14 2001-05-01 Eclipse Surgical Technologies, Inc. Therapeutic and diagnostic agent delivery
US5840059A (en) * 1995-06-07 1998-11-24 Cardiogenesis Corporation Therapeutic and diagnostic agent delivery
DE69634014D1 (en) 1995-06-23 2005-01-13 Gyrus Medical Ltd An electrosurgical instrument
US6780180B1 (en) 1995-06-23 2004-08-24 Gyrus Medical Limited Electrosurgical instrument
CA2224975A1 (en) 1995-06-23 1997-01-09 Gyrus Medical Limited An electrosurgical instrument
US6293942B1 (en) 1995-06-23 2001-09-25 Gyrus Medical Limited Electrosurgical generator method
US6023638A (en) 1995-07-28 2000-02-08 Scimed Life Systems, Inc. System and method for conducting electrophysiological testing using high-voltage energy pulses to stun tissue
WO1997004702A1 (en) * 1995-07-28 1997-02-13 Ep Technologies, Inc. Systems and methods for conducting electrophysiological testing using high-voltage energy pulses to stun heart tissue
US6156031A (en) * 1995-08-09 2000-12-05 Eclipse Surgical Technologies Transmyocardial revascularization using radiofrequency energy
US6267757B1 (en) 1995-08-09 2001-07-31 Eclipse Surgical Technologies, Inc. Revascularization with RF ablation
US5824005A (en) * 1995-08-22 1998-10-20 Board Of Regents, The University Of Texas System Maneuverable electrophysiology catheter for percutaneous or intraoperative ablation of cardiac arrhythmias
US5649936A (en) * 1995-09-19 1997-07-22 Real; Douglas D. Stereotactic guide apparatus for use with neurosurgical headframe
US6428538B1 (en) 1995-10-20 2002-08-06 United States Surgical Corporation Apparatus and method for thermal treatment of body tissue
US5897553A (en) * 1995-11-02 1999-04-27 Medtronic, Inc. Ball point fluid-assisted electrocautery device
US6013076A (en) * 1996-01-09 2000-01-11 Gyrus Medical Limited Electrosurgical instrument
US6015406A (en) 1996-01-09 2000-01-18 Gyrus Medical Limited Electrosurgical instrument
GB9600377D0 (en) * 1996-01-09 1996-03-13 Gyrus Medical Ltd Electrosurgical instrument
US6090106A (en) 1996-01-09 2000-07-18 Gyrus Medical Limited Electrosurgical instrument
US6033397A (en) * 1996-03-05 2000-03-07 Vnus Medical Technologies, Inc. Method and apparatus for treating esophageal varices
EP0969773B1 (en) 1997-03-04 2007-01-03 Vnus Medical Technologies, Inc. Apparatus for treating venous insufficiency using directionally applied energy
US6139527A (en) * 1996-03-05 2000-10-31 Vnus Medical Technologies, Inc. Method and apparatus for treating hemorrhoids
US6036687A (en) * 1996-03-05 2000-03-14 Vnus Medical Technologies, Inc. Method and apparatus for treating venous insufficiency
US6152899A (en) 1996-03-05 2000-11-28 Vnus Medical Technologies, Inc. Expandable catheter having improved electrode design, and method for applying energy
AU733465B2 (en) 1996-03-05 2001-05-17 Tyco Healthcare Group, Lp Vascular catheter-based system for heating tissue
US6016452A (en) * 1996-03-19 2000-01-18 Kasevich; Raymond S. Dynamic heating method and radio frequency thermal treatment
US5779699A (en) * 1996-03-29 1998-07-14 Medtronic, Inc. Slip resistant field focusing ablation catheter electrode
NL1003024C2 (en) * 1996-05-03 1997-11-06 Tjong Hauw Sie Stimulus Conduction Block Instrument.
US5800428A (en) * 1996-05-16 1998-09-01 Angeion Corporation Linear catheter ablation system
DE19621099C2 (en) * 1996-05-24 1999-05-20 Sulzer Osypka Gmbh Device having a catheter and a pierceable from the inside into the heart wall as the high frequency needle electrode
GB9612993D0 (en) 1996-06-20 1996-08-21 Gyrus Medical Ltd Electrosurgical instrument
GB2314274A (en) 1996-06-20 1997-12-24 Gyrus Medical Ltd Electrode construction for an electrosurgical instrument
US6565561B1 (en) 1996-06-20 2003-05-20 Cyrus Medical Limited Electrosurgical instrument
EP0928135B1 (en) 1996-07-17 2006-06-14 Medtronic, Inc. System for enhancing cardiac signal sensing by cardiac pacemakers through genetic treatment
DE69736862T2 (en) * 1996-07-17 2007-05-31 Medtronic, Inc., Minneapolis Delivery system for delivering genetic material to cardiac tissue
US6126682A (en) 1996-08-13 2000-10-03 Oratec Interventions, Inc. Method for treating annular fissures in intervertebral discs
US6106521A (en) * 1996-08-16 2000-08-22 United States Surgical Corporation Apparatus for thermal treatment of tissue
US6544260B1 (en) * 1996-08-20 2003-04-08 Oratec Interventions, Inc. Method for treating tissue in arthroscopic environment using precooling and apparatus for same
EP1007111B1 (en) 1996-10-02 2005-09-14 Medtronic, Inc. Fluid-assisted electrocautery device
US8308719B2 (en) 1998-09-21 2012-11-13 St. Jude Medical, Atrial Fibrillation Division, Inc. Apparatus and method for ablating tissue
AU775394B2 (en) 1999-07-19 2004-07-29 St. Jude Medical, Atrial Fibrillation Division, Inc. Apparatus and method for ablating tissue
US5827268A (en) * 1996-10-30 1998-10-27 Hearten Medical, Inc. Device for the treatment of patent ductus arteriosus and method of using the device
US20030178032A1 (en) * 1997-08-13 2003-09-25 Surx, Inc. Noninvasive devices, methods, and systems for shrinking of tissues
US7317949B2 (en) * 1996-11-08 2008-01-08 Ams Research Corporation Energy induced bulking and buttressing of tissues for incontinence
US6091995A (en) * 1996-11-08 2000-07-18 Surx, Inc. Devices, methods, and systems for shrinking tissues
US6071303A (en) * 1996-12-08 2000-06-06 Hearten Medical, Inc. Device for the treatment of infarcted tissue and method of treating infarcted tissue
GB9626512D0 (en) 1996-12-20 1997-02-05 Gyrus Medical Ltd An improved electrosurgical generator and system
US6749617B1 (en) * 1997-11-04 2004-06-15 Scimed Life Systems, Inc. Catheter and implants for the delivery of therapeutic agents to tissues
US6086582A (en) * 1997-03-13 2000-07-11 Altman; Peter A. Cardiac drug delivery system
US6416510B1 (en) 1997-03-13 2002-07-09 Biocardia, Inc. Drug delivery catheters that attach to tissue and methods for their use
US6547787B1 (en) 1997-03-13 2003-04-15 Biocardia, Inc. Drug delivery catheters that attach to tissue and methods for their use
US5906615A (en) * 1997-03-31 1999-05-25 Femrx, Inc. Serpentine ablation/coagulation electrode
US5971983A (en) * 1997-05-09 1999-10-26 The Regents Of The University Of California Tissue ablation device and method of use
US6024740A (en) 1997-07-08 2000-02-15 The Regents Of The University Of California Circumferential ablation device assembly
US6012457A (en) 1997-07-08 2000-01-11 The Regents Of The University Of California Device and method for forming a circumferential conduction block in a pulmonary vein
EP0996380B1 (en) 1997-07-18 2005-01-05 Medtronic, Inc. Electrosurgery device
US6096037A (en) 1997-07-29 2000-08-01 Medtronic, Inc. Tissue sealing electrosurgery device and methods of sealing tissue
US6480746B1 (en) 1997-08-13 2002-11-12 Surx, Inc. Noninvasive devices, methods, and systems for shrinking of tissues
US9023031B2 (en) 1997-08-13 2015-05-05 Verathon Inc. Noninvasive devices, methods, and systems for modifying tissues
US6035238A (en) * 1997-08-13 2000-03-07 Surx, Inc. Noninvasive devices, methods, and systems for shrinking of tissues
WO1999008614A1 (en) 1997-08-13 1999-02-25 Surx, Inc. Noninvasive devices, methods, and systems for shrinking of tissues
US6081749A (en) * 1997-08-13 2000-06-27 Surx, Inc. Noninvasive devices, methods, and systems for shrinking of tissues
US6402719B1 (en) 1997-09-05 2002-06-11 Cordis Webster, Inc. Steerable DMR catheter with infusion tube
US6024739A (en) * 1997-09-05 2000-02-15 Cordis Webster, Inc. Method for detecting and revascularizing ischemic myocardial tissue
US6179832B1 (en) * 1997-09-11 2001-01-30 Vnus Medical Technologies, Inc. Expandable catheter having two sets of electrodes
US5995875A (en) * 1997-10-01 1999-11-30 United States Surgical Apparatus for thermal treatment of tissue
US6045565A (en) * 1997-11-04 2000-04-04 Scimed Life Systems, Inc. Percutaneous myocardial revascularization growth factor mediums and method
US6416490B1 (en) * 1997-11-04 2002-07-09 Scimed Life Systems, Inc. PMR device and method
US6151525A (en) * 1997-11-07 2000-11-21 Medtronic, Inc. Method and system for myocardial identifier repair
US6775574B1 (en) 1997-11-07 2004-08-10 Medtronic, Inc. Method and system for myocardial infarction repair
US7031775B2 (en) 1997-11-07 2006-04-18 Medtronic, Inc. Method and system for myocardial infarction repair
AU2001215860C1 (en) 2000-09-01 2006-09-07 Medtronic, Inc. Method and system for myocardial infarction repair
US6671558B1 (en) 1997-11-07 2003-12-30 Medtronic, Inc. Method and system for myocardial infarction repair
US6120476A (en) * 1997-12-01 2000-09-19 Cordis Webster, Inc. Irrigated tip catheter
US6280441B1 (en) 1997-12-15 2001-08-28 Sherwood Services Ag Apparatus and method for RF lesioning
US6997885B2 (en) * 1998-04-08 2006-02-14 Senorx, Inc. Dilation devices and methods for removing tissue specimens
US6659105B2 (en) 1998-02-26 2003-12-09 Senorx, Inc. Tissue specimen isolating and damaging device and method
US6540695B1 (en) 1998-04-08 2003-04-01 Senorx, Inc. Biopsy anchor device with cutter
CA2321671C (en) 1998-03-02 2009-07-14 Atrionix, Inc. Tissue ablation system and method for forming long linear lesion
US6875182B2 (en) 1998-03-03 2005-04-05 Senorx, Inc. Electrosurgical specimen-collection system
US6638234B2 (en) 1998-03-03 2003-10-28 Senorx, Inc. Sentinel node location and biopsy
US6679851B2 (en) 1998-09-01 2004-01-20 Senorx, Inc. Tissue accessing and anchoring device and method
US6497706B1 (en) 1998-03-03 2002-12-24 Senorx, Inc. Biopsy device and method of use
US6261241B1 (en) * 1998-03-03 2001-07-17 Senorx, Inc. Electrosurgical biopsy device and method
US6517498B1 (en) 1998-03-03 2003-02-11 Senorx, Inc. Apparatus and method for tissue capture
US6758848B2 (en) * 1998-03-03 2004-07-06 Senorx, Inc. Apparatus and method for accessing a body site
US6540693B2 (en) 1998-03-03 2003-04-01 Senorx, Inc. Methods and apparatus for securing medical instruments to desired locations in a patients body
US6047700A (en) * 1998-03-30 2000-04-11 Arthrocare Corporation Systems and methods for electrosurgical removal of calcified deposits
AU3374799A (en) * 1998-03-31 1999-10-18 Cardiogenesis Corporation Delivery of an angiogenic substance
GB9807303D0 (en) 1998-04-03 1998-06-03 Gyrus Medical Ltd An electrode assembly for an electrosurgical instrument
US6296630B1 (en) 1998-04-08 2001-10-02 Biocardia, Inc. Device and method to slow or stop the heart temporarily
US6493589B1 (en) 1998-05-07 2002-12-10 Medtronic, Inc. Methods and apparatus for treatment of pulmonary conditions
US6327505B1 (en) 1998-05-07 2001-12-04 Medtronic, Inc. Method and apparatus for rf intraluminal reduction and occlusion
US6527767B2 (en) * 1998-05-20 2003-03-04 New England Medical Center Cardiac ablation system and method for treatment of cardiac arrhythmias and transmyocardial revascularization
US6428537B1 (en) 1998-05-22 2002-08-06 Scimed Life Systems, Inc. Electrophysiological treatment methods and apparatus employing high voltage pulse to render tissue temporarily unresponsive
US6837885B2 (en) * 1998-05-22 2005-01-04 Scimed Life Systems, Inc. Surgical probe for supporting inflatable therapeutic devices in contact with tissue in or around body orifices and within tumors
US6107699A (en) * 1998-05-22 2000-08-22 Scimed Life Systems, Inc. Power supply for use in electrophysiological apparatus employing high-voltage pulses to render tissue temporarily unresponsive
US6575931B1 (en) 1998-06-04 2003-06-10 Biosense Webster, Inc. Catheter with injection needle
US6905476B2 (en) * 1998-06-04 2005-06-14 Biosense Webster, Inc. Catheter with injection needle
US6623473B1 (en) * 1998-06-04 2003-09-23 Biosense Webster, Inc. Injection catheter with multi-directional delivery injection needle
US6540725B1 (en) * 1998-06-04 2003-04-01 Biosense Webster, Inc. Injection catheter with controllably extendable injection needle
US8079982B1 (en) 1998-06-04 2011-12-20 Biosense Webster, Inc. Injection catheter with needle electrode
US7416547B2 (en) * 1999-03-29 2008-08-26 Biosense Webster Inc. Injection catheter
US6623474B1 (en) 1998-06-04 2003-09-23 Biosense Webster, Inc. Injection catheter with needle stop
US6322559B1 (en) * 1998-07-06 2001-11-27 Vnus Medical Technologies, Inc. Electrode catheter having coil structure
US6537248B2 (en) 1998-07-07 2003-03-25 Medtronic, Inc. Helical needle apparatus for creating a virtual electrode used for the ablation of tissue
US6706039B2 (en) * 1998-07-07 2004-03-16 Medtronic, Inc. Method and apparatus for creating a bi-polar virtual electrode used for the ablation of tissue
US6238393B1 (en) 1998-07-07 2001-05-29 Medtronic, Inc. Method and apparatus for creating a bi-polar virtual electrode used for the ablation of tissue
US6537272B2 (en) 1998-07-07 2003-03-25 Medtronic, Inc. Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue
US6494902B2 (en) * 1998-07-07 2002-12-17 Medtronic, Inc. Method for creating a virtual electrode for the ablation of tissue and for selected protection of tissue during an ablation
US6409722B1 (en) 1998-07-07 2002-06-25 Medtronic, Inc. Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue
US6302903B1 (en) 1998-07-07 2001-10-16 Medtronic, Inc. Straight needle apparatus for creating a virtual electrode used for the ablation of tissue
US6315777B1 (en) 1998-07-07 2001-11-13 Medtronic, Inc. Method and apparatus for creating a virtual electrode used for the ablation of tissue
WO2000002612A2 (en) * 1998-07-10 2000-01-20 Medtronic, Inc. Medical device and method for transmyocardial revascularization
US6112123A (en) * 1998-07-28 2000-08-29 Endonetics, Inc. Device and method for ablation of tissue
US6102887A (en) * 1998-08-11 2000-08-15 Biocardia, Inc. Catheter drug delivery system and method for use
EP1104328A1 (en) * 1998-08-14 2001-06-06 K.U. Leuven Research & Development Expandable wet electrode
US6208881B1 (en) 1998-10-20 2001-03-27 Micropure Medical, Inc. Catheter with thin film electrodes and method for making same
US6190383B1 (en) 1998-10-21 2001-02-20 Sherwood Services Ag Rotatable electrode device
US6328735B1 (en) 1998-10-30 2001-12-11 E.P., Limited Thermal ablation system
WO2000025850A1 (en) * 1998-10-30 2000-05-11 Windsor Ting Medicinal agent administration catheter device
US6463334B1 (en) 1998-11-02 2002-10-08 Cardiac Pacemakers, Inc. Extendable and retractable lead
US6171275B1 (en) 1998-12-03 2001-01-09 Cordis Webster, Inc. Irrigated split tip electrode catheter
CA2320097C (en) 1998-12-09 2009-04-14 Cook Incorporated Hollow, curved, superelastic medical needle
US6620139B1 (en) 1998-12-14 2003-09-16 Tre Esse Progettazione Biomedica S.R.L. Catheter system for performing intramyocardiac therapeutic treatment
GB2347084B (en) * 1999-02-26 2003-02-12 Medtronic Inc Ablation lead for atrial flutter
US6165164A (en) * 1999-03-29 2000-12-26 Cordis Corporation Catheter for injecting therapeutic and diagnostic agents
US8285393B2 (en) * 1999-04-16 2012-10-09 Laufer Michael D Device for shaping infarcted heart tissue and method of using the device
US6577902B1 (en) * 1999-04-16 2003-06-10 Tony R. Brown Device for shaping infarcted heart tissue and method of using the device
US6939346B2 (en) 1999-04-21 2005-09-06 Oratec Interventions, Inc. Method and apparatus for controlling a temperature-controlled probe
US6292700B1 (en) 1999-09-10 2001-09-18 Surx, Inc. Endopelvic fascia treatment for incontinence
US7229469B1 (en) * 1999-10-02 2007-06-12 Quantumcor, Inc. Methods for treating and repairing mitral valve annulus
US6514248B1 (en) * 1999-10-15 2003-02-04 Neothermia Corporation Accurate cutting about and into tissue volumes with electrosurgically deployed electrodes
US6745080B2 (en) 1999-11-22 2004-06-01 Scimed Life Systems, Inc. Helical and pre-oriented loop structures for supporting diagnostic and therapeutic elements in contact with body tissue
US6711444B2 (en) 1999-11-22 2004-03-23 Scimed Life Systems, Inc. Methods of deploying helical diagnostic and therapeutic element supporting structures within the body
US7097641B1 (en) 1999-12-09 2006-08-29 Cryocath Technologies Inc. Catheter with cryogenic and heating ablation
US6501990B1 (en) 1999-12-23 2002-12-31 Cardiac Pacemakers, Inc. Extendable and retractable lead having a snap-fit terminal connector
US6520927B1 (en) * 2000-01-14 2003-02-18 John D. Unsworth Method and device to prevent cardiac dysrhythmias
US7706882B2 (en) 2000-01-19 2010-04-27 Medtronic, Inc. Methods of using high intensity focused ultrasound to form an ablated tissue area
US8221402B2 (en) 2000-01-19 2012-07-17 Medtronic, Inc. Method for guiding a medical device
EP1435867B1 (en) 2001-09-05 2010-11-17 Salient Surgical Technologies, Inc. Fluid-assisted medical devices and systems
US8048070B2 (en) 2000-03-06 2011-11-01 Salient Surgical Technologies, Inc. Fluid-assisted medical devices, systems and methods
JP2004500207A (en) 2000-03-06 2004-01-08 ティシューリンク・メディカル・インコーポレーテッドTissuelink Medical,Inc. Fluid delivery system and electrosurgical instrument controller
US7811282B2 (en) 2000-03-06 2010-10-12 Salient Surgical Technologies, Inc. Fluid-assisted electrosurgical devices, electrosurgical unit with pump and methods of use thereof
US6770070B1 (en) 2000-03-17 2004-08-03 Rita Medical Systems, Inc. Lung treatment apparatus and method
US6478776B1 (en) 2000-04-05 2002-11-12 Biocardia, Inc. Implant delivery catheter system and methods for its use
US20020107514A1 (en) * 2000-04-27 2002-08-08 Hooven Michael D. Transmural ablation device with parallel jaws
US6514250B1 (en) * 2000-04-27 2003-02-04 Medtronic, Inc. Suction stabilized epicardial ablation devices
US6546935B2 (en) 2000-04-27 2003-04-15 Atricure, Inc. Method for transmural ablation
DE60111517T2 (en) 2000-04-27 2006-05-11 Medtronic, Inc., Minneapolis Vibration-sensitive ablation
US6458123B1 (en) 2000-04-27 2002-10-01 Biosense Webster, Inc. Ablation catheter with positional sensor
US6558382B2 (en) * 2000-04-27 2003-05-06 Medtronic, Inc. Suction stabilized epicardial ablation devices
US6488680B1 (en) 2000-04-27 2002-12-03 Medtronic, Inc. Variable length electrodes for delivery of irrigated ablation
WO2001095820A1 (en) 2000-06-13 2001-12-20 Atrionix, Inc. Surgical ablation probe for forming a circumferential lesion
US6669691B1 (en) 2000-07-18 2003-12-30 Scimed Life Systems, Inc. Epicardial myocardial revascularization and denervation methods and apparatus
US6493591B1 (en) * 2000-07-19 2002-12-10 Medtronic, Inc. Implantable active fixation lead with guidewire tip
US6613017B1 (en) * 2000-08-08 2003-09-02 Scimed Life Systems, Inc. Controlled depth injection device and method
US6893421B1 (en) 2000-08-08 2005-05-17 Scimed Life Systems, Inc. Catheter shaft assembly
US6595958B1 (en) * 2000-08-08 2003-07-22 Scimed Life Systems, Inc. Tortuous path injection device and method
US6558385B1 (en) * 2000-09-22 2003-05-06 Tissuelink Medical, Inc. Fluid-assisted medical device
US7306591B2 (en) 2000-10-02 2007-12-11 Novasys Medical, Inc. Apparatus and methods for treating female urinary incontinence
US6926669B1 (en) 2000-10-10 2005-08-09 Medtronic, Inc. Heart wall ablation/mapping catheter and method
US6582400B1 (en) * 2000-10-24 2003-06-24 Scimed Life Systems, Inc. Variable tip catheter
US6530914B1 (en) 2000-10-24 2003-03-11 Scimed Life Systems, Inc. Deflectable tip guide in guide system
US6616626B2 (en) * 2000-12-21 2003-09-09 Scimed Life Systems, Inc. Infusion devices and method
US6447443B1 (en) * 2001-01-13 2002-09-10 Medtronic, Inc. Method for organ positioning and stabilization
US7628780B2 (en) * 2001-01-13 2009-12-08 Medtronic, Inc. Devices and methods for interstitial injection of biologic agents into tissue
US7740623B2 (en) 2001-01-13 2010-06-22 Medtronic, Inc. Devices and methods for interstitial injection of biologic agents into tissue
ES2257539T3 (en) * 2001-02-28 2006-08-01 Rex Medical, L.P. Apparatus for supplying fluid for ablative treatment of injuries.
US6989004B2 (en) 2001-02-28 2006-01-24 Rex Medical, L.P. Apparatus for delivering ablation fluid to treat lesions
US7087040B2 (en) 2001-02-28 2006-08-08 Rex Medical, L.P. Apparatus for delivering ablation fluid to treat lesions
US6689131B2 (en) 2001-03-08 2004-02-10 Tissuelink Medical, Inc. Electrosurgical device having a tissue reduction sensor
US6497704B2 (en) * 2001-04-04 2002-12-24 Moshe Ein-Gal Electrosurgical apparatus
US6989010B2 (en) 2001-04-26 2006-01-24 Medtronic, Inc. Ablation system and method of use
US7250048B2 (en) * 2001-04-26 2007-07-31 Medtronic, Inc. Ablation system and method of use
US6699240B2 (en) 2001-04-26 2004-03-02 Medtronic, Inc. Method and apparatus for tissue ablation
US7959626B2 (en) 2001-04-26 2011-06-14 Medtronic, Inc. Transmural ablation systems and methods
US6663627B2 (en) 2001-04-26 2003-12-16 Medtronic, Inc. Ablation system and method of use
US6807968B2 (en) 2001-04-26 2004-10-26 Medtronic, Inc. Method and system for treatment of atrial tachyarrhythmias
US6648883B2 (en) 2001-04-26 2003-11-18 Medtronic, Inc. Ablation system and method of use
WO2003026525A1 (en) * 2001-09-28 2003-04-03 Rita Medical Systems, Inc. Impedance controlled tissue ablation apparatus and method
US8396549B2 (en) * 2001-11-29 2013-03-12 Medtronic, Inc. Papillary muscle stimulation
US7546166B2 (en) * 2001-11-29 2009-06-09 Medtronic, Inc. Medical lead designs for lead placement through tissue
US20040230283A1 (en) * 2001-11-29 2004-11-18 Medtronic, Inc. Trans-septal pacing method and apparatus
US6656175B2 (en) 2001-12-11 2003-12-02 Medtronic, Inc. Method and system for treatment of atrial tachyarrhythmias
US7311708B2 (en) 2001-12-12 2007-12-25 Tissuelink Medical, Inc. Fluid-assisted medical devices, systems and methods
US7967816B2 (en) 2002-01-25 2011-06-28 Medtronic, Inc. Fluid-assisted electrosurgical instrument with shapeable electrode
US6827715B2 (en) * 2002-01-25 2004-12-07 Medtronic, Inc. System and method of performing an electrosurgical procedure
WO2003068055A2 (en) * 2002-02-11 2003-08-21 Arthrocare Corporation Electrosurgical apparatus and methods for laparoscopy
US8882755B2 (en) * 2002-03-05 2014-11-11 Kimberly-Clark Inc. Electrosurgical device for treatment of tissue
US6896675B2 (en) 2002-03-05 2005-05-24 Baylis Medical Company Inc. Intradiscal lesioning device
US8518036B2 (en) 2002-03-05 2013-08-27 Kimberly-Clark Inc. Electrosurgical tissue treatment method
US8043287B2 (en) * 2002-03-05 2011-10-25 Kimberly-Clark Inc. Method of treating biological tissue
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
ITBS20020046U1 (en) 2002-04-23 2003-10-23 Fogazzi Di Venturelli Andrea & Instrument with at least two radio frequency active filaments to treat tumors
CA2487280A1 (en) * 2002-05-08 2003-11-20 The Regents Of The University Of California System and method for forming a substantially non-ablative cardiac conduction block
US6953461B2 (en) 2002-05-16 2005-10-11 Tissuelink Medical, Inc. Fluid-assisted medical devices, systems and methods
US7294143B2 (en) 2002-05-16 2007-11-13 Medtronic, Inc. Device and method for ablation of cardiac tissue
US7118566B2 (en) 2002-05-16 2006-10-10 Medtronic, Inc. Device and method for needle-less interstitial injection of fluid for ablation of cardiac tissue
US6887237B2 (en) * 2002-07-22 2005-05-03 Medtronic, Inc. Method for treating tissue with a wet electrode and apparatus for using same
US7156803B2 (en) 2002-08-19 2007-01-02 Depuy Spine, Inc. Devices for controlling fluid flow through a medium
US8361067B2 (en) 2002-09-30 2013-01-29 Relievant Medsystems, Inc. Methods of therapeutically heating a vertebral body to treat back pain
US10028753B2 (en) 2008-09-26 2018-07-24 Relievant Medsystems, Inc. Spine treatment kits
US7103418B2 (en) * 2002-10-02 2006-09-05 Medtronic, Inc. Active fluid delivery catheter
AU2002952318A0 (en) * 2002-10-29 2002-11-14 Advanced Metal Coatings Pty Limited Production of lesions in a body
JP2006504472A (en) 2002-10-29 2006-02-09 ティシューリンク・メディカル・インコーポレーテッドTissuelink Medical,Inc. Fluid auxiliary electrosurgical scissors and methods
US7083620B2 (en) 2002-10-30 2006-08-01 Medtronic, Inc. Electrosurgical hemostat
US7317950B2 (en) * 2002-11-16 2008-01-08 The Regents Of The University Of California Cardiac stimulation system with delivery of conductive agent
US20040106896A1 (en) * 2002-11-29 2004-06-03 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US7844347B2 (en) * 2002-12-06 2010-11-30 Medtronic, Inc. Medical devices incorporating carbon nanotube material and methods of fabricating same
US20040138621A1 (en) 2003-01-14 2004-07-15 Jahns Scott E. Devices and methods for interstitial injection of biologic agents into tissue
US6984232B2 (en) * 2003-01-17 2006-01-10 St. Jude Medical, Daig Division, Inc. Ablation catheter assembly having a virtual electrode comprising portholes
US7387629B2 (en) * 2003-01-21 2008-06-17 St. Jude Medical, Atrial Fibrillation Division, Inc. Catheter design that facilitates positioning at tissue to be diagnosed or treated
US6932804B2 (en) 2003-01-21 2005-08-23 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US7819866B2 (en) * 2003-01-21 2010-10-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation catheter and electrode
US6960207B2 (en) * 2003-01-21 2005-11-01 St Jude Medical, Daig Division, Inc. Ablation catheter having a virtual electrode comprising portholes and a porous conductor
US9408592B2 (en) 2003-12-23 2016-08-09 Senorx, Inc. Biopsy device with aperture orientation and improved tip
US6923808B2 (en) * 2003-02-24 2005-08-02 Boston Scientific Scimed, Inc. Probes having helical and loop shaped inflatable therapeutic elements
EP1605866B1 (en) * 2003-03-03 2016-07-06 Syntach AG Electrical conduction block implant device
US9398967B2 (en) * 2004-03-02 2016-07-26 Syntach Ag Electrical conduction block implant device
US7938828B2 (en) * 2003-03-28 2011-05-10 Boston Scientific Scimed, Inc. Cooled ablation catheter
US7497857B2 (en) 2003-04-29 2009-03-03 Medtronic, Inc. Endocardial dispersive electrode for use with a monopolar RF ablation pen
US8246974B2 (en) 2003-05-02 2012-08-21 Surmodics, Inc. Medical devices and methods for producing the same
WO2004098565A2 (en) 2003-05-02 2004-11-18 Surmodics, Inc. Implantable controlled release bioactive agent delivery device
US7789877B2 (en) 2003-07-02 2010-09-07 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation catheter electrode arrangement
US7235070B2 (en) * 2003-07-02 2007-06-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation fluid manifold for ablation catheter
US7101362B2 (en) 2003-07-02 2006-09-05 St. Jude Medical, Atrial Fibrillation Division, Inc. Steerable and shapable catheter employing fluid force
EP1651127B1 (en) 2003-07-16 2012-10-31 Arthrocare Corporation Rotary electrosurgical apparatus
US7945337B2 (en) * 2003-08-27 2011-05-17 Medtronic, Inc. High impedance and low polarization electrode
US7156843B2 (en) * 2003-09-08 2007-01-02 Medtronic, Inc. Irrigated focal ablation tip
US7207989B2 (en) * 2003-10-27 2007-04-24 Biosense Webster, Inc. Method for ablating with needle electrode
SE526861C2 (en) * 2003-11-17 2005-11-15 Syntach Ag The tissue lesion creating device and a set of devices for treatment of disorders in the heart rhythm regulation system
US8360990B2 (en) 2004-12-16 2013-01-29 Senorx, Inc. Biopsy device with aperture orientation and improved tip
US20050267467A1 (en) * 2004-01-16 2005-12-01 Saurav Paul Bipolar conforming electrode catheter and methods for ablation
US7727232B1 (en) 2004-02-04 2010-06-01 Salient Surgical Technologies, Inc. Fluid-assisted medical devices and methods
US20050187545A1 (en) * 2004-02-20 2005-08-25 Hooven Michael D. Magnetic catheter ablation device and method
US7530980B2 (en) * 2004-04-14 2009-05-12 Atricure, Inc Bipolar transmural ablation method and apparatus
US20070016181A1 (en) * 2004-04-29 2007-01-18 Van Der Weide Daniel W Microwave tissue resection tool
US7244254B2 (en) * 2004-04-29 2007-07-17 Micrablate Air-core microwave ablation antennas
US20060276781A1 (en) * 2004-04-29 2006-12-07 Van Der Weide Daniel W Cannula cooling and positioning device
WO2006127847A2 (en) * 2005-05-24 2006-11-30 Micrablate, Llc Microwave surgical device
US7467015B2 (en) * 2004-04-29 2008-12-16 Neuwave Medical, Inc. Segmented catheter for tissue ablation
US8333764B2 (en) 2004-05-12 2012-12-18 Medtronic, Inc. Device and method for determining tissue thickness and creating cardiac ablation lesions
WO2005112812A1 (en) 2004-05-14 2005-12-01 Medtronic, Inc. Method and devices for treating atrial fibrillation by mass ablation
WO2005112814A2 (en) 2004-05-17 2005-12-01 C.R. Bard, Inc. Irrigated catheter
WO2005120376A2 (en) 2004-06-02 2005-12-22 Medtronic, Inc. Ablation device with jaws
EP1750607A2 (en) 2004-06-02 2007-02-14 Medtronic, Inc. Loop ablation apparatus and method
EP1750606B1 (en) 2004-06-02 2010-05-05 Medtronic, Inc. Compound bipolar ablation device
EP1761188B1 (en) 2004-06-02 2011-07-20 Medtronic, Inc. Clamping ablation tool
US8926635B2 (en) * 2004-06-18 2015-01-06 Medtronic, Inc. Methods and devices for occlusion of an atrial appendage
US8409219B2 (en) 2004-06-18 2013-04-02 Medtronic, Inc. Method and system for placement of electrical lead inside heart
US8663245B2 (en) 2004-06-18 2014-03-04 Medtronic, Inc. Device for occlusion of a left atrial appendage
US7226447B2 (en) * 2004-06-23 2007-06-05 Smith & Nephew, Inc. Electrosurgical generator
WO2006002366A2 (en) * 2004-06-24 2006-01-05 Surmodics, Inc. Biodegradable ocular devices, methods and systems
WO2006023130A2 (en) * 2004-08-12 2006-03-02 Surmodics, Inc. Biodegradable controlled release bioactive agent delivery device
US7635353B2 (en) * 2004-09-22 2009-12-22 St. Jude Medical, Atrial Fibrillation Division, Inc. Transseptal puncture needles and needle assemblies
US8114110B2 (en) * 2004-09-22 2012-02-14 St. Jude Medical, Atrial Fibrillation Division, Inc. Transseptal puncture needle and needle assemblies
WO2006042246A2 (en) * 2004-10-08 2006-04-20 Syntach Ag Two-stage scar generation for treating atrial fibrillation
US7455670B2 (en) * 2005-01-14 2008-11-25 Co-Repair, Inc. System and method for the treatment of heart tissue
US20070156210A1 (en) * 2005-01-14 2007-07-05 Co-Repair, Inc., A California Corporation Method for the treatment of heart tissue
US7536225B2 (en) * 2005-01-21 2009-05-19 Ams Research Corporation Endo-pelvic fascia penetrating heating systems and methods for incontinence treatment
US10064540B2 (en) 2005-02-02 2018-09-04 Intuitive Surgical Operations, Inc. Visualization apparatus for transseptal access
US8137333B2 (en) 2005-10-25 2012-03-20 Voyage Medical, Inc. Delivery of biological compounds to ischemic and/or infarcted tissue
US8078266B2 (en) 2005-10-25 2011-12-13 Voyage Medical, Inc. Flow reduction hood systems
US8050746B2 (en) 2005-02-02 2011-11-01 Voyage Medical, Inc. Tissue visualization device and method variations
US7860556B2 (en) 2005-02-02 2010-12-28 Voyage Medical, Inc. Tissue imaging and extraction systems
US8221310B2 (en) 2005-10-25 2012-07-17 Voyage Medical, Inc. Tissue visualization device and method variations
US9510732B2 (en) 2005-10-25 2016-12-06 Intuitive Surgical Operations, Inc. Methods and apparatus for efficient purging
US7930016B1 (en) 2005-02-02 2011-04-19 Voyage Medical, Inc. Tissue closure system
US7860555B2 (en) 2005-02-02 2010-12-28 Voyage Medical, Inc. Tissue visualization and manipulation system
US9055906B2 (en) 2006-06-14 2015-06-16 Intuitive Surgical Operations, Inc. In-vivo visualization systems
US7918787B2 (en) 2005-02-02 2011-04-05 Voyage Medical, Inc. Tissue visualization and manipulation systems
US9095325B2 (en) 2005-05-23 2015-08-04 Senorx, Inc. Tissue cutting member for a biopsy device
JP2008541878A (en) * 2005-05-26 2008-11-27 スミス アンド ネフュー インコーポレーテッド Electric heating intervertebral disc treatment
US7419486B2 (en) * 2005-06-15 2008-09-02 St. Jude Medical, Atrial Fibrillation Division, Inc. Treatment and diagnostic catheters with hydrogel electrodes
US7776034B2 (en) * 2005-06-15 2010-08-17 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation catheter with adjustable virtual electrode
US7819868B2 (en) 2005-06-21 2010-10-26 St. Jude Medical, Atrial Fibrilation Division, Inc. Ablation catheter with fluid distribution structures
US7655003B2 (en) 2005-06-22 2010-02-02 Smith & Nephew, Inc. Electrosurgical power control
US7879030B2 (en) 2005-07-27 2011-02-01 St. Jude Medical, Atrial Fibrillation Division, Inc. Multipolar, virtual-electrode catheter with at least one surface electrode and method for ablation
US8317725B2 (en) 2005-08-05 2012-11-27 Senorx, Inc. Biopsy device with fluid delivery to tissue specimens
US7572236B2 (en) 2005-08-05 2009-08-11 Senorx, Inc. Biopsy device with fluid delivery to tissue specimens
US7416552B2 (en) 2005-08-22 2008-08-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Multipolar, multi-lumen, virtual-electrode catheter with at least one surface electrode and method for ablation
US20080294229A1 (en) * 2006-10-17 2008-11-27 Friedman Paul A Helical Electrodes for Intramyocardial Pacing and Sensing
CA2638029A1 (en) * 2006-01-27 2007-08-09 Medtronic, Inc. Ablation device and system for guiding said ablation device into a patient's body
US8099177B2 (en) * 2006-03-02 2012-01-17 St. Jude Medical Ab Implantable medical lead and method for the manufacture thereof
EP1998698A1 (en) * 2006-03-24 2008-12-10 Micrablate Transmission line with heat transfer ability
WO2007112102A1 (en) * 2006-03-24 2007-10-04 Micrablate Center fed dipole for use with tissue ablation systems, devices, and methods
EP2010276B1 (en) * 2006-04-26 2014-01-22 Covidien LP Multi-stage microporation device
US20090318804A1 (en) * 2006-05-02 2009-12-24 Galil Medical Ltd. Cryotherapy Planning and Control System
US9326756B2 (en) * 2006-05-17 2016-05-03 St. Jude Medical, Atrial Fibrillation Division, Inc. Transseptal catheterization assembly and methods
US20080039746A1 (en) 2006-05-25 2008-02-14 Medtronic, Inc. Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions
US20080027350A1 (en) * 2006-07-13 2008-01-31 Advanced Cardiovascular Systems, Inc. Methods and apparatus for localization, diagnosis, contact or activity detection of bio-electric tissue
US20080045938A1 (en) * 2006-07-14 2008-02-21 Micrablate Energy delivery systems and uses thereof
US10004388B2 (en) 2006-09-01 2018-06-26 Intuitive Surgical Operations, Inc. Coronary sinus cannulation
JP2010502313A (en) 2006-09-01 2010-01-28 ボエッジ メディカル, インコーポレイテッド Method and apparatus for the treatment of atrial fibrillation
US20080097476A1 (en) 2006-09-01 2008-04-24 Voyage Medical, Inc. Precision control systems for tissue visualization and manipulation assemblies
US20080172012A1 (en) * 2006-10-31 2008-07-17 Hiniduma-Lokuge Prasanga D Injection needle having lateral delivery ports and method for the manufacture thereof
EP2094352A4 (en) 2006-12-06 2010-05-19 Cleveland Clinic Foundation Method and system for treating acute heart failure by neuromodulation
US8131350B2 (en) 2006-12-21 2012-03-06 Voyage Medical, Inc. Stabilization of visualization catheters
US8758229B2 (en) 2006-12-21 2014-06-24 Intuitive Surgical Operations, Inc. Axial visualization systems
CN100574719C (en) * 2006-12-26 2009-12-30 上海导向医疗系统有限公司 Gas throttling cooling type radio frequency ablation electrode
AU2008245600B2 (en) 2007-04-27 2013-07-04 Covidien Lp Systems and methods for treating hollow anatomical structures
JP2010524651A (en) 2007-04-27 2010-07-22 ボエッジ メディカル, インコーポレイテッド Steerable tissue visualization and manipulation the catheter with a complex shape
US8657805B2 (en) 2007-05-08 2014-02-25 Intuitive Surgical Operations, Inc. Complex shape steerable tissue visualization and manipulation catheter
EP2155036B1 (en) 2007-05-11 2016-02-24 Intuitive Surgical Operations, Inc. Visual electrode ablation systems
US8235985B2 (en) 2007-08-31 2012-08-07 Voyage Medical, Inc. Visualization and ablation system variations
US8353907B2 (en) 2007-12-21 2013-01-15 Atricure, Inc. Ablation device with internally cooled electrodes
US8998892B2 (en) 2007-12-21 2015-04-07 Atricure, Inc. Ablation device with cooled electrodes and methods of use
WO2009086448A1 (en) 2007-12-28 2009-07-09 Salient Surgical Technologies, Inc. Fluid-assisted electrosurgical devices, methods and systems
US8255035B2 (en) * 2007-12-31 2012-08-28 St. Jude Medical, Atrial Fibrillation Division, Inc. Coated hypodermic needle
US8858609B2 (en) 2008-02-07 2014-10-14 Intuitive Surgical Operations, Inc. Stent delivery under direct visualization
US20090254083A1 (en) * 2008-03-10 2009-10-08 Hansen Medical, Inc. Robotic ablation catheter
EP2359762B1 (en) 2008-03-31 2013-03-06 Applied Medical Resources Corporation Electrosurgical system selectively configurable for cutting or coagulation
US8801665B2 (en) * 2008-04-10 2014-08-12 Henry Ford Health System Apparatus and method for controlled depth of injection into myocardial tissue
US7959648B2 (en) * 2008-04-22 2011-06-14 Medtronic Vascular, Inc. Device and method for effecting hemostasis about a puncture
US20090275894A1 (en) * 2008-05-01 2009-11-05 Curtis Guy P Transvenous soaker catheter
US8821488B2 (en) 2008-05-13 2014-09-02 Medtronic, Inc. Tissue lesion evaluation
US9770297B2 (en) * 2008-06-04 2017-09-26 Covidien Lp Energy devices and methods for treating hollow anatomical structures
US9101735B2 (en) 2008-07-07 2015-08-11 Intuitive Surgical Operations, Inc. Catheter control systems
US20100204690A1 (en) * 2008-08-13 2010-08-12 Arthrocare Corporation Single aperture electrode assembly
US8747400B2 (en) 2008-08-13 2014-06-10 Arthrocare Corporation Systems and methods for screen electrode securement
US8333012B2 (en) 2008-10-10 2012-12-18 Voyage Medical, Inc. Method of forming electrode placement and connection systems
US8894643B2 (en) 2008-10-10 2014-11-25 Intuitive Surgical Operations, Inc. Integral electrode placement and connection systems
US9468364B2 (en) 2008-11-14 2016-10-18 Intuitive Surgical Operations, Inc. Intravascular catheter with hood and image processing systems
WO2010062394A2 (en) * 2008-11-26 2010-06-03 Surmodics, Inc. Implantable ocular drug delivery device and methods
US8355799B2 (en) 2008-12-12 2013-01-15 Arthrocare Corporation Systems and methods for limiting joint temperature
US9320565B2 (en) * 2008-12-31 2016-04-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Ablation devices, systems and method for measuring cooling effect of fluid flow
US9254168B2 (en) 2009-02-02 2016-02-09 Medtronic Advanced Energy Llc Electro-thermotherapy of tissue using penetrating microelectrode array
JP5592409B2 (en) 2009-02-23 2014-09-17 サリエント・サージカル・テクノロジーズ・インコーポレーテッド Fluid assisted electrosurgical devices and methods of use thereof
WO2011017168A2 (en) 2009-07-28 2011-02-10 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US9072890B2 (en) 2009-09-03 2015-07-07 Mayo Foundation For Medical Education And Research Pacing, sensing or defibrillator leads for implantation into the myocardium
JP2013503723A (en) 2009-09-08 2013-02-04 サリエント・サージカル・テクノロジーズ・インコーポレーテッド Cartridge assembly, electrosurgical unit for the electrosurgical device, and methods for their use
US8317786B2 (en) 2009-09-25 2012-11-27 AthroCare Corporation System, method and apparatus for electrosurgical instrument with movable suction sheath
US8323279B2 (en) 2009-09-25 2012-12-04 Arthocare Corporation System, method and apparatus for electrosurgical instrument with movable fluid delivery sheath
EP2327366B1 (en) * 2009-11-30 2012-03-14 Sorin CRM SAS Kit for piercing the cardiac septum and implanting a transseptal probe, in particular a probe for detection/stimulation of a left cavity of the heart
US8694071B2 (en) 2010-02-12 2014-04-08 Intuitive Surgical Operations, Inc. Image stabilization techniques and methods
WO2011112991A1 (en) 2010-03-11 2011-09-15 Salient Surgical Technologies, Inc. Bipolar electrosurgical cutter with position insensitive return electrode contact
US9814522B2 (en) 2010-04-06 2017-11-14 Intuitive Surgical Operations, Inc. Apparatus and methods for ablation efficacy
US8696659B2 (en) 2010-04-30 2014-04-15 Arthrocare Corporation Electrosurgical system and method having enhanced temperature measurement
CA2800312A1 (en) 2010-05-03 2011-11-10 Neuwave Medical, Inc. Energy delivery systems and uses thereof
US8979838B2 (en) 2010-05-24 2015-03-17 Arthrocare Corporation Symmetric switching electrode method and related system
US20110295249A1 (en) * 2010-05-28 2011-12-01 Salient Surgical Technologies, Inc. Fluid-Assisted Electrosurgical Devices, and Methods of Manufacture Thereof
US9138289B2 (en) 2010-06-28 2015-09-22 Medtronic Advanced Energy Llc Electrode sheath for electrosurgical device
US8906012B2 (en) 2010-06-30 2014-12-09 Medtronic Advanced Energy Llc Electrosurgical devices with wire electrode
US8920417B2 (en) 2010-06-30 2014-12-30 Medtronic Advanced Energy Llc Electrosurgical devices and methods of use thereof
EP2593028B1 (en) * 2010-09-15 2017-08-16 Icecure Medical Ltd. Cryosurgical instrument for treating large volume of tissue
EP2621389B1 (en) 2010-10-01 2015-03-18 Applied Medical Resources Corporation Electrosurgical instrument with jaws and with an electrode
US9023040B2 (en) 2010-10-26 2015-05-05 Medtronic Advanced Energy Llc Electrosurgical cutting devices
JP6023071B2 (en) * 2010-11-30 2016-11-09 フューグリスタ,ファビアン,ヘルマン,ウルバン Spiral insertion tool
US9486275B2 (en) 2010-12-30 2016-11-08 Avent, Inc. Electrosurgical apparatus having a sensor
JP6317927B2 (en) 2012-01-09 2018-04-25 ムー・メディカル・デバイスズ・エルエルシーMoe Medical Devices Llc Plasma-assisted skin treatment
US9427281B2 (en) 2011-03-11 2016-08-30 Medtronic Advanced Energy Llc Bronchoscope-compatible catheter provided with electrosurgical device
KR20140022883A (en) 2011-04-12 2014-02-25 써메디컬, 인코포레이티드 Devices and methods for shaping therapy in fluid enhanced ablation
US8657212B2 (en) * 2011-07-29 2014-02-25 Biomet Biologics, Llc Multi-fluid blending spray tip for coaxial syringe
US9351790B2 (en) 2011-09-17 2016-05-31 M.O.E. Medical Devices Llc Electrode geometries and method for applying electric field treatment to parts of the body
US9750565B2 (en) 2011-09-30 2017-09-05 Medtronic Advanced Energy Llc Electrosurgical balloons
US9629675B2 (en) 2011-10-19 2017-04-25 Confluent Medical Technologies, Inc. Tissue treatment device and related methods
US8870864B2 (en) 2011-10-28 2014-10-28 Medtronic Advanced Energy Llc Single instrument electrosurgery apparatus and its method of use
JP2015503963A (en) 2011-12-21 2015-02-05 ニューウェーブ メディカル,インコーポレイテッドNeuwave Medical,Inc. Energy supply system and methods of use thereof
US9308355B2 (en) 2012-06-01 2016-04-12 Surmodies, Inc. Apparatus and methods for coating medical devices
US9827401B2 (en) 2012-06-01 2017-11-28 Surmodics, Inc. Apparatus and methods for coating medical devices
US9226792B2 (en) 2012-06-12 2016-01-05 Medtronic Advanced Energy Llc Debridement device and method
US8951296B2 (en) * 2012-06-29 2015-02-10 Medtronic Ardian Luxembourg S.A.R.L. Devices and methods for photodynamically modulating neural function in a human
US10022176B2 (en) 2012-08-15 2018-07-17 Thermedical, Inc. Low profile fluid enhanced ablation therapy devices and methods
CN104703556B (en) * 2012-08-28 2017-05-24 波士顿科学西美德公司 Having renal radiofrequency ablation system and related method for using the movable dummy electrodes
CN102824197B (en) * 2012-09-21 2017-11-17 复旦大学附属华山医院 A method for the left ventricle helical electrode stem cell transplantation
CN102940525A (en) * 2012-10-17 2013-02-27 上海安通医疗科技有限公司 Multi-pole helicoidal radiofrequency ablation conduit
EP2914186B1 (en) 2012-11-05 2019-03-13 Relievant Medsystems, Inc. Systems for creating curved paths through bone and modulating nerves within the bone
US10231867B2 (en) 2013-01-18 2019-03-19 Auris Health, Inc. Method, apparatus and system for a water jet
US9717551B2 (en) 2013-02-21 2017-08-01 Carefusion 2200, Inc. Intravertebral tissue ablation device and method
US20140276764A1 (en) * 2013-03-14 2014-09-18 Gyrus ACM, Inc. (d.b.a Olympus Surgical Technologies America) Flexible RF Ablation Needle
US9033972B2 (en) 2013-03-15 2015-05-19 Thermedical, Inc. Methods and devices for fluid enhanced microwave ablation therapy
US9498112B1 (en) 2013-03-15 2016-11-22 Brent Stewart Laryngoscope
US9610396B2 (en) 2013-03-15 2017-04-04 Thermedical, Inc. Systems and methods for visualizing fluid enhanced ablation therapy
US9724151B2 (en) 2013-08-08 2017-08-08 Relievant Medsystems, Inc. Modulating nerves within bone using bone fasteners
US9987082B2 (en) 2013-09-05 2018-06-05 Mitragen, Inc. Valve treatment devices, systems, and methods
CN104688331A (en) * 2013-12-09 2015-06-10 上海安通医疗科技有限公司 Catheter device used for regulating nerves
US9855402B2 (en) 2014-02-15 2018-01-02 Rex Medical, L.P. Apparatus for delivering fluid to treat renal hypertension
US9526556B2 (en) 2014-02-28 2016-12-27 Arthrocare Corporation Systems and methods systems related to electrosurgical wands with screen electrodes
EP3117779A4 (en) * 2014-03-12 2017-11-15 Olympus Corporation Treatment device and treatment system
JP2017515645A (en) 2014-05-16 2017-06-15 アプライド メディカル リソーシーズ コーポレイション Electrosurgical system
US9649148B2 (en) 2014-07-24 2017-05-16 Arthrocare Corporation Electrosurgical system and method having enhanced arc prevention
US9597142B2 (en) 2014-07-24 2017-03-21 Arthrocare Corporation Method and system related to electrosurgical procedures
US9974599B2 (en) 2014-08-15 2018-05-22 Medtronic Ps Medical, Inc. Multipurpose electrosurgical device
USD748259S1 (en) 2014-12-29 2016-01-26 Applied Medical Resources Corporation Electrosurgical instrument
US10188456B2 (en) 2015-02-18 2019-01-29 Medtronic Xomed, Inc. Electrode assembly for RF energy enabled tissue debridement device
US10231793B2 (en) 2015-10-30 2019-03-19 Auris Health, Inc. Object removal through a percutaneous suction tube
CA3015372A1 (en) 2016-03-09 2017-09-14 CARDIONOMIC, Inc. Cardiac contractility neurostimulation systems and methods
US9743984B1 (en) 2016-08-11 2017-08-29 Thermedical, Inc. Devices and methods for delivering fluid to tissue during ablation therapy
US10194975B1 (en) 2017-07-11 2019-02-05 Medtronic Advanced Energy, Llc Illuminated and isolated electrosurgical apparatus

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US35330A (en) * 1862-05-20 Improved foot corn-planter
DE651428C (en) * 1935-12-13 1937-10-13 Koch & Sterzel Ag Electrode for electro-medical purposes, preferably coagulation, for connection to a high frequency apparatus
US3380448A (en) * 1964-11-24 1968-04-30 Abbott Lab Cervical-pudendal indwelling catheter set with tissue piercing means
US4026301A (en) * 1975-04-21 1977-05-31 Medtronic, Inc. Apparatus and method for optimum electrode placement in the treatment of disease syndromes such as spinal curvature
US4209019A (en) * 1979-01-05 1980-06-24 Medtronic, Inc. Stylet insertion guide and rotation control device for use with body implantable lead
US4674499A (en) * 1980-12-08 1987-06-23 Pao David S C Coaxial bipolar probe
US4524770A (en) * 1983-01-25 1985-06-25 Ahmad Orandi Endoscope injection needle
SE459711B (en) * 1987-03-20 1989-07-31 Swedemed Ab Equipment foer anvaendning in surgery PROGRAM TO avlaegsna vaevnader
US5165421A (en) * 1987-09-30 1992-11-24 Lake Region Manufacturing Co., Inc. Hollow lumen cable apparatus
DE3825631C2 (en) * 1988-07-28 1992-03-19 Peter Dr.-Ing. 7889 Grenzach-Wyhlen De Osypka
US5030204A (en) * 1988-09-28 1991-07-09 Advanced Cardiovascular Systems, Inc. Guiding catheter with controllable distal tip
US5003992A (en) * 1989-08-23 1991-04-02 Holleman Timothy W Atraumatic screw-in lead
US5002067A (en) * 1989-08-23 1991-03-26 Medtronic, Inc. Medical electrical lead employing improved penetrating electrode
US5104393A (en) * 1989-08-30 1992-04-14 Angelase, Inc. Catheter
US5060660A (en) * 1990-02-28 1991-10-29 C. R. Bard, Inc. Steerable extendable guidewire with adjustable tip
US5122137A (en) * 1990-04-27 1992-06-16 Boston Scientific Corporation Temperature controlled rf coagulation
US5083565A (en) * 1990-08-03 1992-01-28 Everest Medical Corporation Electrosurgical instrument for ablating endocardial tissue
US5122138A (en) * 1990-11-28 1992-06-16 Manwaring Kim H Tissue vaporizing accessory and method for an endoscope
WO1992020290A1 (en) * 1991-05-17 1992-11-26 Innerdyne Medical, Inc. Method and device for thermal ablation
GB9118670D0 (en) * 1991-08-30 1991-10-16 Mcnicholas Thomas A Surgical devices and uses thereof
EP0680351B1 (en) * 1991-09-05 1998-08-05 Mayo Foundation For Medical Education And Research Flexible tubular device for use in medical applications
US5246014A (en) * 1991-11-08 1993-09-21 Medtronic, Inc. Implantable lead system
US5437660A (en) * 1991-12-30 1995-08-01 Trimedyne, Inc. Tissue ablation and a lateral-lasing fiber optic device therefor
US5242441A (en) * 1992-02-24 1993-09-07 Boaz Avitall Deflectable catheter with rotatable tip electrode
US5281218A (en) * 1992-06-05 1994-01-25 Cardiac Pathways Corporation Catheter having needle electrode for radiofrequency ablation
US5370675A (en) * 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
US5334193A (en) * 1992-11-13 1994-08-02 American Cardiac Ablation Co., Inc. Fluid cooled ablation catheter
US5348554A (en) * 1992-12-01 1994-09-20 Cardiac Pathways Corporation Catheter for RF ablation with cooled electrode
US5336222A (en) * 1993-03-29 1994-08-09 Boston Scientific Corporation Integrated catheter for diverse in situ tissue therapy
US5403311A (en) * 1993-03-29 1995-04-04 Boston Scientific Corporation Electro-coagulation and ablation and other electrotherapeutic treatments of body tissue
US5542944A (en) * 1993-04-19 1996-08-06 Bhatta; Krishan M. Surgical device and method
US5454807A (en) * 1993-05-14 1995-10-03 Boston Scientific Corporation Medical treatment of deeply seated tissue using optical radiation
US5431649A (en) * 1993-08-27 1995-07-11 Medtronic, Inc. Method and apparatus for R-F ablation
US5458597A (en) * 1993-11-08 1995-10-17 Zomed International Device for treating cancer and non-malignant tumors and methods

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